Spike, karakter Tom and Jerry, adalah seekor anjing bulldog penjaga yang galak dan pemarah, yang selalu menyerang Tom. Ia biasanya berteman-baik dengan Jerry, menjadi pengawal dan pelindung tikus itu. Di dalam beberapa episode, ia mempunyai anak yang bernama Tyke. Spike kadang-kadang dijuluki "Killer".

Penampilan

Tom and Jerry 
 Dog Trouble
 The Bodyguard
 Puttin' on the Dog
 Quiet Please!
 Solid Serenade
 Cat Fishin'
 The Invisible Mouse
 The Truce Hurts
 Love That Pup
 The Framed Cat
 Slicked-up Pup
 Cat Napping
 Fit to be Tied
 The Dog House
 That's My Pup!
 Two Little Indians
 Life with Tom
 Hic-cup Pup
 Pet Peeve
 Pup on a Picnic
 Smarty Cat
 Barbecue Brawl
 Tops with Pops
 Tom's Photo Finish
 Tot Watcher
 Mathee Mouse'
  The Karate Guard Spike and Tyke 
 Give and Tyke Scat Cats The Tom and Jerry Comedy Show 
 Spike's Birthday Tom and Jerry Works 
 Football Fail
 Franken-Spike
 Scrambled Cakes
 Jailbirds
 Delivery Cat
 Dog Pounded
 Sailor Mouse
 Achoo!

 Tom and Jerry Tales 
 Feeding Time Joy Riding Jokers Spook House Mouse Beefcake Tom Spaced Out Cat Dog-Gone Hill Hog Beach Bully Bingo Tomcat Jetpack Jackhammered Cat
 Zent Out of Shape
 I Dream of Meanie
  Bend It Like Thomas
 Game, Set, Match! 24 Karat Kat Catfish Follies DJ Jerry Game of Mouse & Cat The Tom and Jerry Show 2014 TV series 
 Spike Gets Skooled Sleep Disorder Birth day Bashed Birds of a Feather Enter in dand Bred kind Tom-Foolery Belly Achin Dog Daze For the Love or Ruggles Sleuth or Consequenses Here' s Lookin'A-choo kid What a Pain Top-Cat Domestic Kingdom Just Plane Nuts  Pets Not Welcome  Crusin' For a Brusin'  Road Trippin' Penampilan lain 
 Tom and Jerry Show 2014 Tom and Jerry Kids Tom and Jerry Comedy Show The Mansion Cat Tom and Jerry: The Magic Ring Tom and Jerry: Blast Off to Mars Tom and Jerry: Shiver Me Whiskers Tom and Jerry: The Fast and the Furry Pengisi suara 
 Billy Bletcher (1944 - 1948)
 Daws Butler (1949 - 1957)
 John Stephenson: The Tom and Jerry Show (1975) Lou Scheimer: The Tom and Jerry Comedy Show Dick Gautier: Tom & Jerry Kids Jim Cummings; Tom and Jerry Works Maurice LaMarche: Tom and Jerry: The Magic Ring Frank Welker: Tom and Jerry: Blast Off to Mars John Di Maggio: Tom and Jerry: The Fast and the Furry John Di Maggio & Jeff Bergman: Tom and Jerry Tales Phill LaMarr Tom and Jerry Meet Sherlock Holmes,Tom and Jerry Robin Hood and his Merry Mouse,Tom and Jerry Giant Adventure''
 Yu Shimaka

Catatan 
 Tokoh Spike tidak merugikan tokoh Droopy.
 Selama tahun 1950-an, Spike terlihat memiliki anak laki-laki bernama Tyke, sebuah karakter tambahan yang menyebabkan melunaknya sikap keras Spike dan munculnya seri animasi "Spike and Tyke" yang berumur pendek. Tyke kadang-kadang berbicara, menggunakan suara dan ekspresi seperti pelawak Jimmy Durante.

Lihat pula 
 Tom and Jerry
 Tom Cat
 Jerry Mouse
 Tuffy
 Tyke

Tom and Jerry