grace bio - labs
grace bio - labs secureslip™ silicone supported coverglass diam. 12 mm | sigma - aldrich
jennipher grudzien, chief executive officer at grace bio - labs, inc. - relationship science
glassdoor gives you an inside look at what it' s like to work at grace bio labs, including salaries, reviews, office photos, and more. this is the grace bio labs company profile. all content is posted anonymously by employees working at grace bio labs .
i applied through a recruiter. i interviewed at grace bio labs (bend, or) in march 2017 .
( p37004) from grace bio - labs allows integration of microscope array technology with automated microtitre plate processing. individual
grace bio - labs strives to be the industry’s elite supplier of research grade cell culture, hybridization, and immunoassay solutions .
the cornerstone of grace bio - labs is our unique capacity to solve intricate research problems. how can we help you ?
hybridization and incubation seals ad chambers from grace bio - labs are ideally suited for in situ - hybridization assays. the adhesive seal of…
grace bio - labs microarray surface chemistry is based on the well - known protein - binding properties of nitrocellulose. a range of different formulations have…
grace bio - labs employees work in a manufacturing area of the company' s building on cyber drive in june. grace bio - labs has leased a building on emkay drive to house the headquarters, manufacturing and customer reception and meeting area. (andy tullis / bulletin file photo )
grace bio - labs employees work in a manufacturing area of the company' s building on cyber drive in june. grace bio - labs has leased a building on emkay drive to house the headquarters, manufacturing and customer reception and meeting area. (andy tullis / bulletin file photo) - bulletin
mcgrath’s scientific innovations at grace - bio labs have advanced cancer research and therapies. he is a proponent of research and education in the bioscience fields .
grace bio - labs is an industry leader for providing high quality tools and protocols to facilitate the use of robust protein and dna microarrays around the world .
grace 7500 grace drive columbia, maryland 21044, usa t + 1 410. 531. 4000
the cornerstone of grace bio - labs’ evolution and success has been our unique capacity to envision and design tools to facilitate protein and cell analysis research and discovery .
grace bio - labs is committed to providing competitive benefits, a healthy environment and flexibility to enjoy all that central oregon has to offer. our 2018 benefits include :
this privacy policy (“policy”) explains how information about you is collected, used, and disclosed by grace bio - labs when you access or use our website .
grace bio - labs is a globally recognized company in biomarker discovery and precision medicine. we strive to be the life science industry’s elite supplier of research - grade cell culture, hybridization, and immunoassay solutions. we started grace bio - labs more than 30 years ago with the desire to gain a deeper understanding of how protein and single - cell interactions were relevant in cancer detection .
grace bio - labs products are 100% satisfaction guaranteed. we sell products which we manufacture in bend oregon. quality is our highest priority, and satisfaction is guaranteed or your product will be replaced .
grace bio - labs’ custom product development also includes partnering with oems to translate their needs into scalable manufacturing and products. we help companies solve the value equation for molecular diagnostics. grace bio - labs is consistently adding new capabilities to meet the needs of our growing customer base better. in 2017, we are pleased to announce the expansion of our research, development, and manufacturing facilities in bend, oregon .
grace bio - labs takes reasonable measures, including administrative, technical, and physical safeguards, to protect information about you from loss, theft, misuse, unauthorized access, disclosure, alteration, and destruction .
oregon state university – cascades has received a $ 1 million gift from charles mcgrath, the founder and president of grace - bio labs of bend, to help construct the next academic building planned on its new campus .
grace bio - labs manufacture innovative labware for the molecular study of cells in situ. the range includes nitrocellulose and nylon - coated microscope slides and a great variety of press to seal enclosures for cell culture and high throughput cytochemistry .
grace bio - labs is growing its customer base in terms of geography and scientific discipline, hale said. she was not available to discuss the company’s growth in detail but answered questions via email while on a medical leave of absence .
grace catalysts technologies and grace materials technologies provide innovative products, technologies and services that improve the products and processes of our customers around the world .
“there’s been definitely an influx of businesses that want to locate close to the college, ” said ron ross, the compass commercial real estate services broker who represented both grace bio - labs and rivers east in the 10 - year lease transaction .
responsive customer service and quality research products are at the foundation of everything we do. grace bio - labs’ quality management system meets all of the requirements for iso 13485 certification. our development partner capabilities help pharmaceutical, biotechnology, and academic researchers advance the field of precision medicine .
the emkay building will house grace’s headquarters offices, manufacturing space and a new “customer experience center” for workshops, scientific meetings, guest speakers and training sessions on grace products, hale said .
promotional communications. you may opt out of receiving promotional emails from grace bio - labs by following the instructions in those communications. if you opt out of receiving promotional communications, we may still send you non - promotional emails, such as emails about your purchases, account, membership or our ongoing business relations .
our microarray technologies, developed early on, include microporous nitrocellulose - coated slides and small incubation chambers. these discoveries soon led to a robust family of molecular diagnostic tools and products as well as our custom manufacturing and product development capabilities. over the past three decades, many scientific discoveries and advancements in precision medicine were made possible with grace bio - labs’ molecular diagnostic tools .
today, grace bio - labs continues to serve the needs of the fast - growing field of biotechnology. we pride ourselves on our ability to develop custom molecular diagnostic tools and products to improve the speed and accuracy of protein and cell analysis research—this is at the foundation of our success. our life science products and custom manufacturing capabilities help researchers innovate solutions for their research .
grace bio - labs inc. , which designs and manufactures lab supplies for researchers around the world, leased 1015 sw emkay drive and plans a major renovation, said lisa hale, the firm’s vice president of commercial development. at the same time, the company grew from 35 to 55 employees last year and plans to add another 20 employees ﻿this year, she said .
grace bio - labs has been designing and developing molecular diagnostics tools, services, and consumable products for more than 30 years. our agile, research - driven biotechnology company prides itself on responsive customer service and is globally recognized for quality in everything we do. we achieve this by inspiring growth and innovative solutions through customer focus, commitment to quality, teamwork, and sustainability .
grace bio - labs may change this policy from time to time. if we make changes, we will notify you by revising the effective date above and, in some cases we may provide you with more prominent notice (such as adding a statement to our homepage or sending you an email notification). we encourage you to review the policy to stay informed about our information practices and the ways you can help protect your privacy .
mcgrath recently led the expansion of grace - bio labs. a second location was established in a district near the new osu campus that is increasingly attracting innovative tech and bioscience companies. meanwhile, the company’s research innovation experts and osu - cascades’ academic leaders are exploring opportunities for collaboration. these opportunities include potential new academic degree offerings and public - private partnerships, with a focus on developing a skilled and professional workforce, and enhancing job creation in the bioscience industry .
with the additional lobby space, grace will occupy 16, 000 square feet, twice as much space as the company has on cyber drive .
the company makes film slides, reagents and other lab supplies for academic and private - industry researchers. grace also designs and makes custom products to facilitate protein and cell analysis. grace was founded by chuck mcgrath and jennipher grudzien, who moved the company to bend from the detroit area in the mid - 1990s .
grace strives to be a premier specialty chemical and materials company. we provide innovative technologies and value - added products and services around the world to enhance the quality of life .
we are dedicated to our vision to develop a biomarker - based companion diagnostic platform that leverages grace’s proprietary film surface and instrumentation technology. this platform is designed to expedite the adoption of personalized or precision medicine for management of chronic diseases, cancer detection and treatment therapies .
the emkay building has been vacant since it was sold by bellatrix systems to a portland investor, rivers east llc, last year for $ 2 million. grace is planning a renovation, plus the addition of a new atrium lobby and outdoor patios and break areas for employees, hale said .
grace’s current home on cyber drive will become an “innovation center” and get its own makeover to accommodate additional lab space and new research disciplines, hale said. the company will provide bicycles and skis or snow shoes for employees to travel about a half - mile between the two sites, she said .
anastassia voronova erin coyne, ashraf al madhoun, joel v. fair, neven bosiljcic, catherine st - louis, grace li, sherry thurig, valerie a. wallace, nadine wiper - bergeron, and ilona s. skerjanc (2013) hedgehog signaling regulates myod expression and activity j biol chem; 288 (6), 4389–4404. pubmedid: 23266826
this product is licensed from bio - rad laboratories, inc. under u. s. pat. nos. 6, 627, 424, 7, 541, 170, 7, 670, 808, 7, 666, 645 and corresponding patents in other countries for use only in: (a) standard (non - real time) pcr in the research field only, but not real - time pcr or digital pcr; (b) any
grace began contemplating an expansion last year, and after considering sites across central oregon decided to stay near the osu - cascades campus, hale said. the company supports an effort at osu - cascades to build a bioscience incubator. the incubator, which is still in fundraising mode, would house startups and eventually broaden the local bioscience industry, which has been driven largely by bend research and its offshoots .
we use the hybriwell system in our transfection array studies, where several hundred cdna clones spotted in an microarray format on a glass slide are incubated with transfection agent. the chamber has turned out to be very reliable in terms of its stable attachment to the glass surface and fluid impermeability. we tested several other small chamber incubation systems and the hybriwell system appeared to be the most efficient one. what is very important is that hybriwell is very easy to position on the surface due to its elasticity. removal of the solution using a pasteur pipet attached to a vacuum does not disturb the chamber, which in our case is crucial to preserve an array arrangement of the cdna spots .
the stability of the once attached hybriwell chamber, however, has its price. detachment of the chamber from the glass surface requires a firm and uniform pull with tipped forceps. it takes some time to get the right feeling for a smooth and uniform removal of the well. we also realized that one should be careful when using highly viscous solutions. we recommend applying them directly onto the chamber surface and then attaching the well to the slide surface .
in summary, the hybriwell system is a straightforward solution for small volume incubations on glass surfaces. it is an efficient way of saving on expensive reagents (e. g. transfection reagents). because of this and our overall good experiences with the hybriwell system, i recommend it to researchers who are looking for this type of tool in the fields of histology and microarray technology .
biocompare is the leading resource for up - to - date product information, product reviews, and new technologies for life scientists .
stay up to date on news and special offers related these products. free subscription !
this website requires javascript to be enabled in order to work properly. please enable javascript to improve your experience .
protein crystallization is a key assay for structural studies of proteins. the protocols for crystallization of protein are challenging due to the stringent requirement for pure samples and control of environmental conditions during the crystallization process. vapor diffusion using hanging drop is a preferred method for obtaining quality crystals with…
proplates® were specifically designed to enable automated robotic liquid handling. two main configurations are available: the proplate® microtiter plate is comprised…
silicone isolators allow researchers to isolate specimens using removable hydrophobic barriers. they may be used to isolate cells grown in…
fastwells™ are sticky, flexible silicone gaskets that form hydrophobic reagent barriers around specimens without messy adhesives or special slides. gaskets may…
coverwell™ incubation chambers are reusable, easy to apply chambers that attach without the use of adhesive. coverwells™ enclose a large…
coverwell ™ perfusion press - to - seal covers form water - tight, multiwell cell incubation or cytochemistry chambers when pressed to coverslips or microscope slides. …
imaging spacers are ultra - thin adhesive spacers which peel - and - stick to coverglass or microscope slides to confine specimens without compression. layer multiple…
adhesive seal tabs complement secureseal™ hybridization chambers, hybriwell™ sealing system and coverwell™ perfusion chambers. once the paper liner is removed, …
to prevent evaporation apply seal strips using the plastic applicator to the top surface of the chamber. seal strips remove cleanly…
silicone isolator™ sheet material allows researchers to create their own removable hydrophobic barriers to isolate specimens. where additional sealing is…
coverwell ™ imaging chambers are designed to stabilize and support thick and free - floating specimens for confocal microscopy and imaging applications. …
mutlislip™ inserts with 8 (18mm x 18mm) or 15 (12mm x 12mm) no. 1. 5 german glass coverglass per insert are…
these adhesive sheets are made using the same secureseal™ adhesive as is used to make hybriwell™ and secureseal™ incubation chambers. thin, …
culturewell™ chambered coverglass products consist of removable and reusable, non - cytotoxic silicone gaskets secured to number 1. 5 german coverglass. chambered coverglass…
gaskets are ideal for forming wells on glass microscope slides or in polystyrene dishes. gaskets are non - sterile and may be…
culturewell™ clear silicone sheet material allows researchers to create their own removable hydrophobic barriers to isolate specimens. they may be…
culturewell™ non removable chambered coverglass, 16 well, no. 1. 5 german borosilicate coverglass. product consists of cell culture vessels, with a…
our innovations in proteomic profiling and microarray technologies are driving leading edge assay development .
our advanced hybridization and incubation chambers include: secureseal™ hybridization chambers; hybriwell™ and coverwell™ incubation chambers; and secureseal™ imaging spacers, which work together to create innovative microfluidic solutions for cell and protein analysis .
our culturewell™ chambered and coverglass products include reusable gaskets, coverglass inserts, and silicone sheet material, which are specifically designed for high resolution microscopy applications. a leak - proof design eliminates well - to - well cross contamination .
as a development partner, our custom manufacturing capabilities help drive research and development in university research laboratories, biotech companies, private research facilities, and pharmaceutical companies. our ability to customize products gives companies the tools they need to better innovate solutions for research and development in precision medicine .
as a leader in the development and manufacture of products that are critical to furthering life science research, we are dedicated to seeking talented, energetic and qualified individuals to join our team .
while the work environment here is informal, our expectations are high, and we understand the best performances come from individuals who know they are part of a valued team .
we encourage thoughtful, energetic, innovative and talented job seekers to check here frequently for opportunities as they change with business necessities. we’re always seeking qualified professionals in the following areas :
401 (k) plan with the company auto - contributing to your retirement regardless if you contribute or not .
community “give back” opportunities; including supporting the fight against cancer, cancer survivorship and clean - up our environment .
direct: 541 - 318 - 1208 toll free: tel: + 1 - 800 - 813 - 7339 internat. : (011) 541 - 318 - 1208 fax: 541 - 318 - 0242
organization name (i. e. , business, school, etc. )
as a leader in the development and manufacture of products critical to furthering life science research, we are dedicated to seeking talented, energetic and qualified individuals to join our team .
a bend bioscience supply company is growing at a rapid clip and will move into a new headquarters building this summer .
“we pride ourselves on not only developing innovative products, but also full - scale manufacturing and (a) world - class quality assurance department, ” hale said in an email. “the new site will allow us to expand our manufacturing, quality and operations capabilities with the addition of new equipment and new employees. ”
type in product names, product numbers, or cas numbers to see suggestions .
our team of scientists has experience in all areas of research including life science, material science, chemical synthesis, chromatography, analytical and many others .
© 2018 merck kgaa, darmstadt, germany and / or its affiliates. all rights reserved. reproduction of any materials from the site is strictly forbidden without permission. sigma - aldrich products are sold exclusively through sigma - aldrich, inc. site use terms | privacy
glassdoor will not work properly unless browser cookie support is enabled. learn how to enable cookies .
explore the many benefits of having a premium branded profile on glassdoor, like increased influence and advanced analytics .
lovely company and people. i enjoyed my interview and ended up getting the job. good pay. i took a different job for scheduling reasons. informal interview but very professional .
copyright © 2008–2018, glassdoor, inc .
glassdoor
and logo are proprietary trademarks of glassdoor, inc .
sign up for a free crunchbase account to follow and track organizations you care about .
terms of service | privacy policy | © 2018 crunchbase inc. all rights reserved .
was founded in 1986 to set new standards for speed and accuracy in cell analysis and molecular pathology. the company has grown through creativity, developing and patenting its own technology .
coverwell imaging chambers are designed to stabilise and support thick and free - floating specimens for confocal microscopy and imaging applications. reusable press - to - seal silicone chambers form removable enclosures for repeat staining or specimen repositioning. flexible coverslip material allows these chambers to be removed from the thinnest coverglass witout breaking the glass or damaging the specimen. new adhesive coverwells are designed to form peel - and - stick leak - proof enclosures for the permanent mounting of thick specimens .
coverwell imaging chambers are designed to stabilise and support thick and free - floating specimens for confocal microscopy and imaging applications. reusable press - to - seal silicone chambers form removable enclosures for repeat staining or specimen repositioning. flexible coverslip material allows these chambers to be removed from the thinnest coverglass witout breaking the glass or damaging the specimen .
reusable culturewell gaskets from culturewell chambered coverglass and culturewell chambered coverglass inserts are available in bulk packages. gaskets are ideal for forming wells in glass microscope slides or in polystyrene dishes. gaskets are non - sterile and may be sterilised by autoclaving, uv or alcohol .
chambered coverglass products consist of removable / reusable non - cytotoxic silicone gaskets secured to 24 mm x 50 mm, number 1. 5 german coverglass. they may be placed in sterile culture plates or 100 mm diameter culture dishes. the thin flat coverglass is the optimal platform for high resolution microscopy and high - sensitivity, quantitative, fluorescent imaging. leak - proof design eliminates well - to - well cross contamination. gaskets stabilise coverglass and provide convenient handling using conventional microscope slide holders and accessories. gaskets are removable for high resolution imaging. gaskets may be resterilised and reused. well spacing facilitates liquid handling utilising multichannel pipettes and robotic dispensers .
four chambered coverglasses, assembled in a disposable frame, placed in a standard 86 mm x 128 mm culture plate, sterile and ready to use. the stabilising insert design and accessory hardware allow fragile coverglass to be easily integrated into protocols for high throughput handling of microscope slides and microtitre plates .
16 well chambered coverglass cell culture vessel has a 2 x 8 format with standard 96 well plate volumes and well spacing. non - cytotoxic silicone well gasket forms a leak proof seal between polystyrene upper structure and coverglass; product is sterile and ready to use. coverglass removal is facilitated using a very simple, single piece device that reliably separates the parts without the need for excessive force or risk of coverglass breakage. silicone removal leaves no residue. components are manufactured and assembled with special orientation features for ease of handling and convenient identification of specimen location after structure removal .
culturewell silicone sheets allow researchers to isolate specimens using removable hydrophobic barriers. they may be used to isolate cells grown in culture dishes or separate multiple specimens affixed to microscope slides .
flow cytometry on a glass slide. designed for multiplex analysis: multiple assays performed on the same cell. binding of virtually all cells .
sticky, flexible silicone gaskets form hydrophobic reagent barriers around specimens without messy adhesives or special slides. fastwells may be stacked to increase depth and volume. they remain sealed during agitated washing steps. fastwells peel off quickly and cleanly, leaving no residue to interfere with specimen coverslip. they can be washed, autoclaved and reused. fastwells can also be sealed to form incubation chambers using flexible hybrislip covers .
flexwells silicone gaskets form wells on slides using clean release adhesive to isolate up to 16 specimens per slide. slides fit into a reusable slide tray, organising wells into the footprint of a microtitre plate. gaskets may be sealed for mixing and to prevent evaporation. fluorescent friendly chambers for sensitive dna microarrays - hybrislip hybridisation covers - hybriwell sealing system - modular hybridisation system - multislip cell culture coverglass inserts - multislip cell culture coverglass inserts .
these new microarray chambers are designed specifically for compatibility with cy5 and alexafluor™ 647 direct labelled dna probes for hybridisation assays. these chambers as well as the original hybriwells can also be used with all other fluorochrome labelled probes .
hybrislips are flexible, thin (0. 25 mm) covers that minimise fluid friction and facilitate uniform reagent distribution. rnase free, hydrophobic covers will not trap or bind probes to their surfaces like coverglass. product is ready - to - use without pre - treatment. working surfaces are protected with clean release liners to prevent rnase contamination. hybrislips remain flat and will not curl, even at high temperatures. product is ideally suited for in situ hybrdisation, in situ pcr and hybridisation to genomic arrays on glass slides .
hybriwell sealing system seals securely to a microscope slide surface in seconds to enclose single or multiple specimens in a small reagent volume and eliminate evaporation. access ports in the chamber surface allow for the addition or removal of reactants. ports are easily sealed using adhesive seal tabs (port seals), provided with each order. sealed chambers are watertight and ideally suited for water bath incubations. rnase free, hydrophobic surfaces will not trap or bind probes. disposable chamber removes cleanly and easily even after heating .
an assortment of flexible, press - to - seal gasket and coverglass enclosures can be quickly assembled and disassembled for the specialised challenges of hybridising and imaging thick and free floating specimens. multiple chambers can be built on one microscope slide. this product is ideally suited for overnight hybridisations and agitated washing steps .
non - gasketed film slides are designed especially for cytocentrifuge preparations. from sealed chambers for incubations using secure - seals .
oncyte is a 3 - dimensional microarray substrate bound to a standard 25 mm x 75 mm glass slide. a combinationof nitrocellulose polymer and proprietary chemistry maximise protein binding and stability. the film is compatible with virtually all detection systems, including fluorescent, chemiluminescent, radiographic and colourimetric. the center - to - center spacing of oncyte multi - films matches that of 96 and 384 well microtitre plate formats. multi - films can be processed using the proplate multiarray system .
multiple nitrocellulose dots affixed to glass microscope slides can be used for cytochemical high throughput screening. nitrocellulose, specially formulated for fluorescent imaging is cast as ultra - thin coatings on premium white glass microscope slides. microporous coating ensures uniform binding of cells and macromolecules. nitrocellulose becomes transparent for microscopy and imaging using a variety of mounting media. removable silicone multiwells isolate specimens and reagents to prevent cross contamination. press - to - seal silicone chambers seal easily to prevent evaporation. gaskets are removed cleanly and easily, simply by peeling them off .
silicone isolators allow researchers to isolate specimens using removable hydrophobic barriers. they may be used to isolate cells grown in culture dishes or separate multiple specimens affixed to microscope slides .
silicone isolators allow researchers to isolate specimens using removable hydrophobic barriers. they may be used to isolate cells grown in culture dishes or separate multiple specimens affixed to microscope slides. silicone isolators are available in silicone thickness 0. 5 to 2. 5 mm. isolators are pre - cut into gaskets or as sheet material with and without secureseal clean release adhesive on one or both surfaces. isolators remain sealed to smooth surfaces during washing steps. non - adhesive isolators are autoclavable and reusable. closed chambers may be formed using flexible rnase free, hybrislip covers .
proplate integrates microscope slide based array technology with automated microtitre plate processing. sixteen individual arrays can be assayed per slide. four slides fit into a tray, producing a modular plate with a standard microtitre plate footprint and well spacing allowing automated robotic processing of 64 arrays. form up to 16 leak - proof wells on any slide surface without the use of adhesive. microtitre plate well - spacing facilitates use with multichannel pipettes. 7 x 7 mm square wells are ideal for high content arrays. 15 - 350 ul well volumes accommodate small reagent and large wash volumes. slides can be assembled easily for processing and disassembled quickly for reading with conventional chip readers due to adhesive - free, snap - clip design .
secureseal imaging spacers are ultra thin adhesive spacers which peel - and - stick to coverglass or microscope slides to confine specimens without compression. layer multiple spacers to custom build chambers to any depth desired. for high resolution microscopy, sandwich specimen and spacer between two no. 0 coverglass .
coverglass is affixed to a thin, microscopically transparent silicone base, which secures it to culture vessels by electrostatic charge (no adhesive), to prevent movement during cultivation, and cells from growing on the back surface. the silicone also acts as a hydrophobic barrier to isolate liquid reagents on glass. individual coverglass with silicone backing can be adhered to a petri dish or plate. these can be easily removed one at a time from the dish during culture. once removed, coverglass can be affixed to microscope slides by means of the tacky silicone backing for routine processing, or placed cell side down onto a reagent using the silicone backing as a cover to prevent evaporation. silicone backing removes easily (by peeling) for conventional mounting on microscope slides. during culture, cells may be imaged without interference from the optical grade silicone .
silicone isolators allow researchers to isolate specimens using removable hydrophobic barriers. they may be used to isolate cells grown in culture dishes or separate multiple specimens affixed to microscope slides. silicone isolators are available in silicone thickness 0. 5 to 2. 5 mm. i solators are pre - cut into gaskets or as sheet material with and without secureseal clean release adhesive on one or both surfaces. isolators remain sealed to smooth surfaces during washing steps. non - adhesive isolators are autoclavable and reusable. closed chambers may be formed using flexible rnase free, hybrislip covers .
proplate® 24 well, silicone gasket only, 6. 8mm x 5. 4mm - 10 pack
if the product you are returning was sent to you in error or is defective, we will pay for return shipping .
if the product you are returning was purchased in error or doesn’t work for your application, you will be responsible for return shipping .
products must be returned undamaged and in original packaging with undamaged labels. products shipped sterile must be unopened .
if you wish to return a product, please contact our customer service department at 1 - 800 - 813 - 7339 or email customer service and we will initiate the return process and provide your return reference number .
information you provide to us. we collect information you provide directly to us. for example, we collect information when you create an online account or profile; make a purchase or and when you email, call, or otherwise communicate with us. the types of information we may collect include :
online account information, such as your name, address, phone number, fax number, email address, demographic information, and information about your interests and preferences .
transaction information, such as your name, billing address, shipping address, phone number, email address, and transaction history .
information we collect when you use our services. we may also automatically collect information about you when you access or use the services, including :
log information: we obtain information about your use of our services, including the type of browser you use, access times, pages viewed, your ip address and the page you visited before navigating to our services .
information we collect from other sources. we may also receive personal information about you from other sources and combine or link that with information we have about you .
your information. you may update or correct information about you by logging into your online account or calling customer service at 1 - 800 - 813 - 7339. you may also email us at service @ urltoken. if you wish to deactivate your account, but note that we may retain information about you for legitimate business purposes or as required by law .
if you have any questions, comments or concerns about this policy or about our privacy practices, please call our customer service department at 1 - 800 - 813 - 7339 or send an email message to service @ urltoken. you may also direct your privacy - related comments or questions to the following address :
the future building will be the second academic building on the campus and will focus on the steam disciplines of science, technology, engineering, arts and mathematics .
“chuck’s gift is an extraordinary statement of leadership and vision, ” said becky johnson, vice president of osu - cascades. “it demonstrates his personal commitment to higher education in central oregon, for osu - cascades’ expansion, as well as for innovative science education. ”
this gift pushes the total funds raised to $ 8. 9 million toward a $ 10 million match required for the state bonding proposed for the new building .
osu - cascades received $ 9. 5 million in capital funding from the oregon state legislature in the recently concluded legislative session. the funding will support the initiation of the campus expansion, allowing for site preparation on the university - owned 46 - acre property adjacent to the existing campus. the state funding also will enable classroom, office and security improvements to the nearby osu - cascades graduate & research center .
osu will seek additional funding for the academic building in the february 2018 legislative session. other donations toward the campus expansion have included a $ 5 million gift from an anonymous donor, $ 1 million gift from the tykeson family foundation, and $ 500, 000 gift from the bend foundation. with the commitment of state funding, the donations will be applied to construction costs for the new academic building .
osu - cascades: oregon state university’s campus in bend, ore. , features outstanding faculty in degree programs that reflect central oregon’s vibrant economy and abundant natural resources. nearly 20 undergraduate majors, 30 minors and options, and 4 graduate programs include computer science, energy systems engineering, kinesiology, hospitality management, and tourism, recreation and adventure leadership. the branch campus expanded to a four - year university in 2015; its new campus opened in 2016 .
cascade business news (cbn), central oregon' s business newspaper, is local and family - owned and operated by jeff martin. cbn is published the first and third wednesdays of each month. cbn is a division of cascade publications inc .
calcium ions (ca2 +) play a crucial physiological role in the body: signalling, blood clotting, in cellular communication, as a messenger, and forming important relationships with proteins and regulators such as vitamin d and parathormone. as a key player in muscle contraction and neuron function, calcium ions have been the subject of thousands of research studies. this research has driven the need for accurate calcium indicators .
scientists at the university of california berkley developed the first fluorescein - based calcium indicator in the 1980s. this breakthrough meant intracellular calcium could be visualised and quantified. this quickly led to the advent of calcium probes such as fluo - 3 am and fluo - 4 am which are now widely used. these fluorescein - based acetoxymethyl (am) esters are hydrophobic and will pass through the cell membrane easily. esterases within the cell hydrolyse the esters soon after entering the cell which enables them to detect calcium. fluo - 3 and fluo - 4 bind to calcium and when shown a ~ 490 nm excitation light, they will fluoresce at ~ 520 nm signal .
unfortunately, the new - found benefits associated with the use of fluorescein - based dyes arrived alongside some significant difficulties. the results obtained were difficult to read accurately because of high background fluorescence (‘noise’). data analysis and bioassays with fluorescein - based dyes became problematic as the calcium probes created false signals, obscured significant results and hid true positives .
calcium indicators have great importance in many fields of research. the issues caused by background fluorescence of fluo - 3 am and fluo - 4 am have been problematic enough to warrant much investigation. the results of extensive research indicate two probable reasons for the generation of this background noise :
the chemical properties of am esters. these esters, like fluo - 3 am and fluo - 4 am, tend to hydrolyse in solution, the acetoxymethyl group is separated from the ester rendering it impermeable and unable to pass through the cell membrane. there will now be a significant proportion of the probe outside the cell creating more background fluorescence. due to the reduced amount of probe that enters the cell the results will show a lower fluorescence signal .
the dyes are also thought to leak through organic anion transporters, possibly because they are poorly localised in the cytosol. this becomes significant later in the article when looking at solutions to the problems. once the dyes are loaded into the cells it appears that fluo - 3 and fluo - 4 can be transported into intracellular organelles or into the extracellular matrix. the result is a similar effect, the fluo - 3 and fluo - 4 that are now outside the cell will fluoresce causing increased baseline fluorescence and potentially masking significant results. this phenomenon is particularly problematic for calcium flux assays and calcium imaging where geospatial quantification of calcium is so important .
to enable interpretation of the results of these bioassays, it is crucial to localise the calcium probe carefully and check that it is being transported efficiently .
clearly, the issues with fluo - 3 and fluo - 4 as calcium indicators needed to be resolved. researchers have suggested many possible solutions, one of which was to use fluo - 3 and fluo - 4 alongside the drug probenecid. probenecid is used in the treatment of gout and hyperuricemia; it also prolongs the physiological effect of other drugs such as penicillin. it is thought that its efficacy is due to its inhibitory effect on organic anion transporter activity within the kidney. this inhibition leads to retention of some compounds like pharmaceutical drugs, prolonging their efficacy. this same mechanism inhibits the organic anion transporter activity that is responsible for causing leakage of fluo - 3 and fluo - 4 from the cell. using probenecid in conjunction with the fluo - 3 and fluo - 4 improves retention, thereby reducing background fluorescence .
fig. 1 atp stimulated calcium response of endogenous p2y receptor in cho - k1 cells. 100 µl of 5 mm fluo - 4 am with (blue) and without (red) the presence of 2. 5 mm probenecid
however, it quickly became apparent that this solution was less than perfect. whilst it had the beneficial effects of reducing fluorescence, it couldn’t be ignored that it is a drug, therefore causing changes to normal cellular functioning. the precise effects on the cell weren’t clear, neither were the implications of those effects to results. this indicated the need to impose additional controls such as probenecid dose, making it a less viable option .
aat bioquest recognised the need to find a solution to the problem of background fluorescence. the result is a [ three - step process ] producing a new, efficient cal - 520 ® indicator, which successfully reduces the amount of background fluorescence .
step 1. to improve localisation and cellular retention. firstly, changes were made to the molecular structure of fluo - 3 and fluo - 4, thereby changing chemical properties that would make the am ester bond far more stable. the result was a greatly reduced incidence of hydrolysis when in solution to improve cell loading. the changes enhanced cellular retention as well as improving localisation .
step 2. synthesis of compound. aat bioquest chemists discovered a reaction path that produced a good yield, thereby keeping costs of production to a minimum .
step 3. scale of production the manufacturing process was fine tuned to ensure the best quality calcium indicator compounds could be produced efficiently, representing good value for the researcher in every respect .
cal - 520 ® am is a dramatic improvement on existing calcium dyes. cal - 520 benefits include :
fig. 2 100 µl of 4 µm fluo - 4 am (left, cat # 20552 - aat), cal 520™ am (right, cat # 21130 - aat) cho - m1 cells illustrating response of endogenous p2y receptor to atp with probenecid. images from a fluorescence microscope using fitc channel .
the result provided by cal - 520 am is significantly lower background fluorescence as well as a greatly improved signal to background ratio. researchers will also find that cal - 520 ® am maintains the spectra seen from fluo - 3 and fluo - 4, this enables the transition from the fluo - 3 am and fluo - 4 am compounds to the cal - 520 ® am compound with no need to alter equipment used .
fig. 3 atp stimulated calcium response of endogenous p2y receptor in cho - k1 cells with cal - 520 ® am (red) compared to fluo - 4 am (blue) .
the cal 520 ® am has also been adapted for use in multiplexing. 590tm am and cal - 630tm am compounds have been created for longer wavelengths. these compounds are equally as reliable and are compatible for use with green fluorescence indicators such as gfp .
cal - 520 ® am is an excellent probe for use with fluorescence - based assay detection of intracellular calcium mobilisation. it allows easy analysis and quantification of gpcr and calcium channel targets and enables screening of agonists and antagonists. cal - 520 ® am can be used with fluorescence spectroscopy, fluorescence microscopy, fluorescence microplate platform and flow cytometry. its applications in the field of research are varied and increasing as its qualities are being realised: neurobiology, cardiology and cell signalling included. cal - 520 ® am is proving extremely valuable in a growing number of research areas, it’s applications in the study of intracellular calcium
stratech scientific have been providing dyes and probes for assay and test research for several years. we are pleased to include the product range from aat bioquest focusing on photometric detection enabling biomedical researchers to obtain an improved understanding in the research areas of molecular biology, cell biology, immunology and biochemistry .
relsci relationships are individuals jennipher grudzien likely has professional access to. a relationship does not necessarily indicate a personal connection .
empower your business applications with industry - leading relationship data from the relsci api .
the cybersecurity 202: twitter' s fake account purge can help turn the tide again ...
creating a news feed is your most valuable research tool. relsci sends you actionable updates so you can keep tabs on the people and organizations you care about most .
browse in - depth profiles on 10 million influential people and organizations. find relsci relationships, employment history, board memberships, donations, awards, and more .
explore notable alumni from top universities and organizations. expand your fundraising pool and make warm introductions to potential new business connections .
harness the power of your relationships with relsci pro, the powerful platform for identifying relationship - driven business opportunities and connections that can propel your career forward .
© 2018 relationship science llc. all rights reserved. certain information provided by factset research system inc .
school of chemical, biological and environmental engineering 116 johnson hall 105 sw 26th st. corvallis, or 97331
it looks like your browser does not have javascript enabled. please turn on javascript and try again .
we are dedicated to our customers. they trust us to provide products, knowledge, technologies, services, and the people to make their products work better .
teamwork: treat each other with respect. work safely and effectively with each other to win in the marketplace. communicate openly and candidly .
speed: work with a sense of urgency to meet our customers' needs. move quickly to seize opportunities in the marketplace. anticipate market shifts and respond before our competitors .
the secureslip ™ coverglass is affixed to a thin microscopically transparent silicone base which secures to culture vessels by an electrostatic charge, not an adhesive, to prevent movement during cultivation. the silicone also acts as a hydrophobic barrier to isolate liquid reagents on glass. individual coverglass with silicone backing can be adhered to a petri dish or plate. these can be easily removed one at a time from the dish during culture. once removed, coverglass can be affixed to a microscope slide by means of the tacky silicone backing for routine processing, or placed cell side down onto a drop of reagent using the silicone backing as a cover to prevent evaporation. • silicone backing peels off easily for conventional mounting on microscope slides • during culture, cells may be imaged without interference from the optical grade silicone • eliminates coverglass overlapping during culture • easily identify
cell side
of coverglass • recommended use temperature is - 62 °c to 218 °c
this was a remarkable project and proud moment for trinamix being the implementation partner for one of the cloud early adopter customer globally .
trinamix is helping multiple customers including a segment leader in digital marketing, a pioneer of biofertilizer industry on their journey to adopt oracle pbcs (planning budgeting cloud services) in record time and empowering them for enterprise budgeting and planning .
oracle scm cloud – the most comprehensive scm suite in the cloud. oracle scm cloud allows customer to deploy functionality incrementally with nominal risk, lower cost and maximum flexibility—all with the benefit of ongoing functional innovation .
– complete, modern suite delivering continuous innovation in key technologies such as mobile, social and analytics deployed in the cloud to achieve more, faster, and with less resources. this helps business to increase productivity with automated financial processing with real time data .
about trinamix: trinamix, is a global company headquartered in california (usa) with sales office in bay area, including regional offices in india, uae, japan & australia. trinamix is a leading implementation specialists for oracle cloud applications, oracle value chain planning and e - business suite. an oracle platinum partner, trinamix partnered with justransform to design cloud based integrated solutions for key interfaces between oracle cloud applications and on premise applications. trinamix brings a rare combination of flawless technical proficiency in oracle cloud products; versatility and innovation; sharp business insights and valuable experience from a wide range of industry and client base .
trinamix is one of the leading implementation specialists for oracle cloud applications. since 2009, trinamix is recognized for customer focus & excellence in solution delivery that ensures clients achieve their vision of an integrated, orchestrated and seamless business process .
get the sharpest, brightest images. try new invitrogen™ prolong™ glass antifade mountant with glass - matching refractive index of 1. 52. learn more
please purchase this product by removing it from your on - site supply center. stocked items are not available for online purchase .
this item is not currently available on - site. depending on your supply center settings you may be able to add the item to cart above else use the order non - stocked items' tab on the supply center home page .
, covered with seal strips (p37002), fit into a tray (p37003), producing a modular plate with a standard microtitre plate footprint, and well spacing. the modular design allows loading of 1 - - 4 slides per tray for plate washing and reading. individual proplate modules may also be processed by hand without the use of the tray. the large well volumes and isolation of 16 individual arrays (2x8) on a single microscope slide is particularly well suited for proteomics applications, including protein expression analysis, protein - protein interactions, antibody profiling, and htp automated analysis of multiple proteins. the proplate system can also be used to process cdna or oligonucleotide arrays .
html public
- / / w3c / / dtd html 4. 01 transitional / / en
urltoken
note: you clicked on an external link, which has been disabled in order to keep your shopping session open .
shared lists are a new way to save products. create a list for each of your projects to share with collaborators like your lab manager. then select and buy products as a team .
click “save to list” to create your first list, give it a name, and add the product. access your shared lists in the account link on urltoken
grace bio-labs is a global supplier of pharmaceutical , biomedical , and biochemical research products based in bend , oregon , united states . they develop the thin-cast nitrocellulose biochip ( aka : nitrocellulose slide , nitrocellulose film slide ) and the modern hybridization and incubation chambers for glass microscope slides . 
grace bio-labs is a global supplier of pharmaceutical, biomedical, and biochemical research products based in bend, oregon, united states. they develop the thin-cast nitrocellulose biochip (aka: nitrocellulose slide, nitrocellulose film slide) and the modern hybridization and incubation chambers for glass microscope slides.
grace bio-labs is a global supplier of pharmaceutical, biomedical, and biochemical research products based in bend, oregon, united states. they develop the thin-cast nitrocellulose biochip (aka: nitrocellulose slide, nitrocellulose film slide) and the modern hybridization and incubation chambers for glass microscope slides.