cryo interactive
external engines with the same name that target other cryo interactive games are listed below .
announced to have acquired the intellectual rights to all of the former cryo interactive video games catalogue as well as all of the cryo brands .
had flopped. parts of the company were absorbed by dreamcatcher interactive, who had published cryo' s games in north america since 1996. successful series like
cryo is the publisher behind the upcoming massively multiplayer online sci - fi role - playing game dune generations. a number of other cryo games have been published in north america through a partnership with canada - based dreamcatcher interactive .
cryo interactive was a french gaming company that was founded in 1992, and closed in 2002 following bankruptcy. many of their games have been highly criticised by critics and gamers .
cryo interactive / networks was dismantled in 2002, due to ongoing debts, and the failure of their last few games, including a true - to - form adaptation of dune .
formed in 1997. the company developed and published online multiplayer games and software applications. cryo networks also maintained a proprietary online multimedia development framework named scol (standard cryo on line) .
on hellboy, the logo popped up still with
cryo studios north america
below it .
. cryo was not a registered company at this time, just a development team. their original logo showed what would become the familiar cryo logo - image (a woman' s face, in a cryo - tube), set inside an inverted form of the exxos logo - image .
the famous logo with a woman' s face in blue cryo - tube (or a space suit) .
the following is a list of windows 95 games published by cryo interactive in the centre for computing history collection. it is not an exhaustive list of and other games may have been published. if you have any games or software that you would like to donate to our collection, please view our donations page .
a compilation of all cryo interactive opening logos, excluding the still versions. oh yeah, the version from aliens: a comic book adventure is included too. the quality for this video is lower than the original because rendering hd videos in sony vegas makes my pc overheat. hopefully, i can render an hd version in the future .
french game company cryo and its subsidiary, cryonetworks, have shut down, according to a report on gaming news site urltoken. the closure is due to a failure to negotiate a deal with the company' s creditors, and cryo shares have been suspended from trading awaiting an announcement from the company' s board of directors .
cryo networks' headquarters was located in france and it opened two divisions in quebec, canada (montreal and laval) which handled sales and distributions to the united states and canada. in january of 2001 the company acquired
38 years old, phd in fundamental computer science. technical architect, project manager and auditor (cryo networks, hsbc, bnp paribas): writing of technical specifications, optimization, process rationalization and automation, development, displaying .
as i searched the cryo titles today, im nearly shocked. only 8 titles in gog market? ?? why? i know cryo games need much more patients sometimes the dated graphipcs, sometimes the crungy and not too logical ui but they definetely has the atmosphere which many modern games doesnt. at least since lost eden has added, but not necronomicon? why its already in steam. or maybe some rights needed? and dune, oh my god? why on earth dune missing from gog? ? ?
if you plan on road tripping around the south this summer, check out the southern foodways alliance' s oral history interactive map. the map features restaurants, roadside stands, and purveyors from virginia to texas with an oral history about each location. use the trip builder to plan an itinerary around the eateries along your route. there are also specific trails for barbecue, boudin, gumbo, and tamales .
the company is a victim of the fallout from the closure of publisher cryo last year, and this news will come as a blow to fans of classic football games such as kick off, goal! and player manager, whose creator dino dini was working with trecision on a new football game .
37 years old, polytechnique degree (x92), phd in economic science, bac + 5 in social science. he worked as a directing consultant, project manager and auditor (cryo networks, hsbc, natexis): strategy, management, organization, process, quality, innovation and networks management .
this is something extremely sad ,
commented trecision managing director pietro montelatici ,
after 12 years with our best game ever in development it' s even worse. cryo' s closure last year hit us heavily and now shareholders decided not to sustain trecision anymore so we had no choice but to close. i would like to thank all the people i worked with here in trecision, they are simply great .
italy' s oldest development studio, trecision, has gone into liquidation after 12 years in business - but the company is hopeful that a buyer may step in to allow the completion of work on its forthcoming football title .
the studio' s previous football title, football generation, is set to be published by midas, and the company is hopeful that it will be able to complete and deliver this title under the court' s supervision. the future of the other football game, however, hinges on a buyer being found for the game assets .
i strongly hope that an interested party will see the huge opportunity to buy part of trecision' s asset, employ the team and finish what can be one of the best soccer game in the market ,
montelatici told gi. biz .
both the project and the team deserve this .
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uk charts: jurassic world narrowly misses no. 1 as crash bandicoot holds firm
, which was published that year, also by virgin. a wide variety of games followed, including early cd - rom best - seller
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there is a purple triangle depicting the anabiosis chamber with face inside. the word
in a decorative (and very abstract) yellow font slides in from the bottom - left corner to the center, and
presents
in the futuristic white font appears at the bottom - right corner .
, which appears in an shell looking right to the bottom. the word
we see the female android again, wearing a space suit with light playing, looking right .
there is a red planet (presumably mars) on the screen. the face slowly pans and turns to look on us, then it freezes and fades through black to
is seen below in the dungeon font. the logo is taken into a box .
for sega cd, the logo is tinted sky blue, due to color limitations .
same action as before, but the red planet is replaced with earth below .
is written directly on it, this time in times new roman font. the name casts shadows .
we start in a close - up of the female android' s face inside the space suit, turned left .
there is a starfield around and a planet is seen. the face pans to the right, with light playing on the glass, and then the box zooms in, with
then two comets are shown, orange and blue, swirling in the skies. the view changes to the face, then to comets again, and to her right eye. the android opens her eyes. then the comets collide and create the
a much more longer version exists, which was likely used for promotional uses .
this is a remake of 6th logo animation. instead of the space suit, a segmented shell opens and show the female android' s face (features changed) inside. the further action is copied from the previous logo, with minor changes .
the videos for the logos above have been found. 4th - urltoken also, here' s an extra logo history. urltoken
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notes: based on wagner' s opera the ring of the nibelungen. it comes on six cds. available in english, french, and greek (only subtitles) .
notes: the cd version is called conspiracy and features a new hint system, interlaced video, and stars donald sutherland .
they have made a number of decent point - and - click adventure games that are still fondly remembered by many nostalgic gamers (although they tend to be short and easy) .
can' t find a community you love? create your own and start something epic .
sony santa monica makes us care about kratos in this stunning revival of the series .
far cry 5' s story is a real let - down, but the action still makes for a solid co - op experience .
there are some elements around the edges that haven' t aged all that well, but burnout paradise is still a fantastic racing game .
podcasts giant bombcast the giant beastcast giant bombcast (premium) the giant beastcast (premium) giant bombcast aftermath! all systems goku premium podcasts giant bomb presents gaming minute 8 - 4 play alt + f1 bombin' the a. m. with scoops and the wolf !
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uk ebay has persian wars. . two listing right now that they are selling to the states one of which is brand new and sealed. . sure there is more than than for sale if you sign into uk ebay. . i am signed into usa ebay
persian wars might play fine if you mess with the hardware acceleration moving it lower away from full or you might try downloading zeus software nglide or dgvoodoo 2 wrapper. . i never played that game. . only played about half of this list
i lost my persian wars cd some time ago, unfortunately. also, last time i tried playing it, there was a weird lag issue when giving commands in combat. i hope gog can get us these games .
yeah mate, i cant seem to find
persian wars
anywhere. gog has t oadd this stuff .
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the engine to support lost eden has been merged into the main tree and the game is completable .
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video games producer and publisher microïds is one of the world leaders in the adventure games segment (with international bestsellers such as still life, syberia, dracula and amerzone). its extensive and varied games catalog has won over every section of the public, from toddlers to hardened gamers, and from collectors of cultural games to adventure fans. microïds' publishing line today is focused on mainstream games, where the core objectives will continue to be gaming and entertainment, fiction and fantasy worlds. some of its titles will also touch on the learning sector (history, science, heritage, current affairs, and much more) .
toki 🐒 sera disponible sur nintendo switch dès le 22 novembre et dévoile son édition retrollector qui contient... - toki en version boite - une bd toki de 16p - des lithographies - des stickers - une mini borne d’arcade pour accueillir l’écran de la nintendo switch !
toki 🐒 sera disponible sur nintendo switch dès le 22 novembre et dévoile son édition retrollector qui contient... … urltoken
le remaster d' astérix et obélix xxl 2 sortira le 29 novembre 2018 sur nintendo switch, playstation 4, xbox one et pc. deux éditions spéciales sont disponibles en précommande! - l’édition limitée astérix & obélix xxl2 qui comprendra le jeu vidéo (playstation 4, nintendo switch ou xbox one) avec 3 figurines d' astérix, obélix et idéfix. - l’édition collector « ils sont fous ces gaulois! » qui inclura le jeu (playstation 4 et nintendo switch), une figure en résine et d’autres surprises à découvrir très prochainement... fin 2019, les joueurs découvriront astérix et obélix xxl 3, un nouveau jeu d' aventure fidèle à l' univers de la bd .
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robyn lee used to take and edit many of the photos for serious eats. she' d also doodle cute stuff when necessary. read more from robyn at her personal food blog, the girl who ate everything .
post whatever you want, just keep it seriously about eats, seriously. we reserve the right to delete off - topic or inflammatory comments. learn more in the comment policy section of our terms of use page .
if you see something not so nice, please, report an inappropriate comment .
and merged it into the montreal location. by december 2001 the laval, canada, location no longer existed. the ceo of the company at that time was
, was abandoned and never released. the scol technology was subsequently released as an open source project .
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is founded by a strong and qualified team, experienced both in technology and television. the team is made of 5 partners, with common values and highly complementary expertise. several of us have already worked together as a team for several years on critical missions .
30 years old, master in finance from hec business school. he worked for france télévisions financial management department (2002 - 2006). he was in charge of financial issues in the launching of dtt tv channels as france 4 and gulli and of the news tv channel france 24. in 2006, he joined france télévisions general management department to develop a performance analysis tool on aired programs. in addition to his responsibilities, he became general manager of a sofica (investment fund dedicated to cinema and tv programs) in july 2005 .
36 years old, master 2 of the european business school. co - founder and commercial manager of degetel, a computer engineering service company specialized in new technologies and the media. it developed its turnover from 0 to 45 m€ in 7 years and was out with a lbo in 2007. cofounder of openbridge, a consulting company .
the viral rna of tmv is infectious by itself, but rna on its own is very unstable. the addition of a 17 - kda coat protein (cp) around the rna protects the rna from degrading and makes tmv very stable. the assembly of a rod - shaped virion begins at a two - turn helical cp complex, called the 20s aggregate (11), which recognizes the initiation motif. this motif contains an aag repeat (11), with the last g being the most conserved (12). each mature tmv is composed of 2, 130 cp molecules and a 6 - kb linear positive - strand rna, organized in a helical rod of 3, 000 å in length and 180 å in diameter. with the protection of cp, tmv can survive for years in cigars and cigarettes made from infected leaves .
here we take advantage of these latest technical developments and further improve the helical reconstruction method. by doing so, we have determined the structure of tmv in its metastable calcium - free state at 3. 3 å resolution by cryoem helical reconstruction. our structure reveals the mechanisms by which the tmv coat protein swaps base favorability (g * a to a * g) in response to the removal of calcium ions from its calcium switches. our structure also explains why both assembly and disassembly can happen with the same components in the same environment .
as detailed in methods, we optimized the acquisition of high - resolution images in three aspects. first, we used a thoroughly cleaned and extensively “baked” holey carbon grid as well as a small beam size to minimize specimen charging. second, we used parallel illumination to eliminate magnification differences across images at different defocus settings. third, we minimized beam tilt to reduce phase errors. electron micrographs of frozen hydrated tmv in the metastable calcium - free state show characteristic striations perpendicular to the helical axes (fig. 1 a). these particles were boxed into segments (see box in fig. 1 a) which were subjected to reference - free 2d classification to obtain class averages. the incoherent average of fourier transforms of these class averages shows layer lines beyond a spacial frequency of 1 / (3. 2 å) (fig. s1 a), demonstrating the resolution limit of the images beyond 3. 2 å .
cryoem reconstruction of tmv at 3. 3 å resolution. (a) cryoem micrograph showing natural striations of the tmv rods embedded in vitreous ice. (scale bar, 600 å .) the image was denoised by applying a wiener filter, a median filter, and a low - pass filter to enhance the contrast. (b) central slice from the final 3d reconstructed map. (c) overview of the helical density map. (d) a single turn of 16 subunits of capsid protein (ribbons in rainbow colors) and bound rna (atomic model at low radius). (e) ribbon diagrams of one cp and its three bound rna bases superimposed with the cryoem density map. see also movie s1. lr, rr, ls, rs: left radial, right radial, left slewed, and right slewed α - helices, respectively .
we first find the upper limit of δ based on the targeted resolution and the crowther formula (21). for the case of tmv, δ has to be less than 1° to achieve 3. 3 å resolution; it also has to be an integral fraction of the angular span of the asymmetric unit, ϕ (in the case of tmv, ϕ = 22. 04°), for the vernier strategy to work. therefore, the available choices of δ for tmv here are ϕ / 22, ϕ / 23, ϕ / 24, and so forth. then we experiment on different combinations of θ and δ that satisfy the following three relationships: first, θ is an integral fraction or an integral multiplicity of ϕ (i. e. , ϕ = mθ); second, δ equals an integral fraction of θ (θ = nδ); and third, n × m is an integer. the nominal angular locations (0, 1θ − 1δ, 2θ − 2δ…), in turn, fall into different asymmetric units at effective angular positions 0, (n − 1 mod mn) δ, (2n − 2 mod mn) δ, (3n − 3 mod mn) δ… relative to the beginnings of each asymmetric unit when helical symmetry is considered (fig. s2 b). after calculating these numbers, we would know whether a certain (θ, δ) pair passes the last quality control: whether the effective angular positions cover all of the 0, δ, 2δ… (mn − 1) δ positions in the asymmetric unit and whether these effective angular positions are evenly distributed within the asymmetric unit (the number of nominal projection locations can be more than the effective positions; in this case, we would like the effective positions of the extra projections to be evenly distributed in the asymmetric unit). if it does not, we try a different pair of θ and δ .
resolution assessment of the 3. 3 å cryoem map. (a – c) representative structural features resolved beyond 3. 3 å resolution. atomic models are shown as sticks and cryoem densities are shown as wire frames. in b, the higher - density regions are displayed in navy color, showing that sugar and phosphate groups 3. 3 å apart are well - resolved. (a and c) the two stacked base groups of the rna (a) and the side chains of the two arginines that are stacked with their π - bonds (c) are 3. 3 å apart. (d – f) representative regions of the map fitted with their atomic model, showing the quality of the map. (d and f) two hydrophobic regions showing the quality of the side - chain densities. (e) the sole small β - sheet region of cp, showing the separation of the strands. see stereo views of d – f in fig. s2 .
carbonyl densities. representative areas of the density map that match with the shape of corresponding backbone carbonyl groups (arrows) .
our reconstructed tmv structure (fig. 1 b – e) has the same overall shape as that of the high - calcium state solved by x - ray fiber diffraction (6). the calculated helicity of our structure is 16. 338 subunits per turn, or 49. 013 subunits per three turns, which is slightly different from those used in previous studies (49. 02 in refs. 6 and 9, and 49. 019 in ref. 23). each asymmetric unit of tmv contains one cp and three rna bases (fig. 1 e). each cp consists of four major helices, two minor helices, and one tiny β - sheet (fig. 2 e). these secondary - structure elements are joined by loops, one of which runs radially and binds rna (rna - binding loop) (fig. 1 e). these loops are well - resolved in our cryoem structure, unlike the previous lower - resolution cryoem structure (9) .
based on this map, we built a full - atom model de novo (methods). in each cp subunit, 155 ordered residues (ser3–ala157) and 3 bases are resolved. using side - chain densities resolved in our map and the counting criterion as described previously (24), we identified in each cp 113 fully resolved amino acids (73 %), 24 partially resolved residues (16 %), 11 ambiguous residues (7 %), and 6 glycines (4 %). notably, even most of the “ambiguous” and glycine residues have defined cα positions. carbonyl groups are at times (> 15 %) visible in the density as protrusions (fig. 3). the rna densities are also well - resolved. phosphate groups sharply stand out at higher contour levels. the densities for the base moieties are in pie shapes similar to those of tryptophan residues .
the other calcium switch, located closer to the helical axis (fig. s4, blue circle), has been described previously (9). the opening of this second switch results in lower affinity between adjacent cp subunits in the lateral direction .
in sum, the net effect of losing calcium ions in the calcium switches is threefold: the lateral interaction between cps is considerably weakened; the axial interaction between cps is strengthened; and the affinity between cp and bound rna is decreased. such effects have changed the tightly bound helical assembly into a loosely bound “beads on a string” structure that is held together by encircling (but not as strongly binding to) the viral rna, making possible the cotranslational stripping of cp by ribosomes during disassembly (6, 26 – 28) .
changes in cp–rna base hydrogen - bonding networks triggered by low - calcium concentration .
environments of the three bases in the low - calcium state shown in stereo. (a and b) environment of base 1: the cases for adenine (a) and guanine (b). the backbone oxygens of gly85 and asp88 make a hydrogen bond with n6 of adenine and n2 of guanine, respectively. when protonated, asp115 can form a hydrogen bond with n3 of this purine (blue dashed lines). (c) environment of base 2. as observed in our structure, the size of the density of this base fits a pyrimidine. if it is a uracil, its o4 forms a hydrogen bond with arg46; its n3 participates in the hydrogen - bond network mediated by a water molecule. (d) environment of base 3. thr89 forms a hydrogen bond with any base in this position with its side - chain oxygen, either as a donor or an acceptor. base 3 favors guanine because only guanine gets an extra hydrogen bond with gln39 .
on the other hand, base 3 now favors guanine. the backbone oxygen of thr89 now turns and its hydrogen bond with base 1 in the high - calcium state is broken. as a consequence, its side - chain oxygen now forms a hydrogen bond with base 3 (fig. 5 d). this hydrogen bond can be formed for all bases. if this base is a guanine, an additional hydrogen bond may form between its n2 and gln39 (fig. 5 d). thus, guanine is more favorable at this base position .
for base 2, the size of the density is too small for a purine; therefore, we model a uracil base at this location (fig. 5 c). o4 of this uracil forms a hydrogen bond with arg46 (fig. 5 c). this hydrogen bond can also be formed with a guanine. a water molecule mediates a hydrogen - bonding network between arg90, thr42, and n3 of this uracil (fig. 5 c). this hydrogen bond can be formed for all bases. it was suggested that this base favors adenine (29); however, in our experiment, we were unable to capture the conformation of an adenine bound in base 2, possibly due to the relatively low abundance of adenine at this base position in the whole viral genome .
the above observations about the changed hydrogen - bonding network at low - calcium concentration on the three base slots are consistent with the notion that an aag - repeating motif is necessary to initiate the encapsidation process (12) .
in the fiber diffraction structure it was concluded that the rna binding site specifically favors a g * a motif. however, the rna binding site revealed in our structure favors an a * g motif instead. both motifs match with the aag motif observed as the initiation motif (12) (the g * a motif can be converted to * ag by applying a frameshift operation). because our structure represents the conformation in a low - calcium - concentration environment, which is the same as that which the virus encounters during assembly, the a * g motif revealed in our structure now offers direct evidence as to why the aag motif initiates the encapsidation process (12) .
particles on the micrographs were selected manually by the helixboxer program in the eman package (31) and subsequently boxed out automatically with a custom - designed program helixbatchboxer that is deposited in the eman repository. this program also cut the helical particles into segments using user - selected overlapping schema. reference - free 2d classification was done with the eman urltoken module (results). the starting model was generated in a similar fashion as previously (32). the 3d structure was refined iteratively as follows for 10 iterations. for every iteration, the current best structure is used as a reference to obtain a refined structure using the eman refine module for one single round; this refined structure is used to refine the helical parameters by the hsearch _ lorentz module of ihrsr (20); the newly determined helical parameters are used to generate a new structure by helicizing the eman reconstruction with the himpose module of ihrsr (20). we used the vernier method to guide projection generation in the eman refinement (results) .
for the himpose program, we made three modifications that are critical for reaching atomic resolutions. first, we modified it to use the central 1 / 5 segment of the volume for averaging, instead of the 2 / 3 that is hard - coded in the original ihrsr program. second, we introduced a new feature so that the helicized map will not shift or rotate in relation to the starting model as the original program does. third, we implemented an oversampling scheme into himpose to minimize interpolation errors introduced during averaging and back - and - forth conversions between cylindrical and cartesian coordinate systems .
upon reaching convergence of the above iterative refinement, we switched to a refinement method similar to that described previously (9), except that we generated our 3d reconstruction by merging class averages (as in eman) instead of individual particles. the reconstructed volume was helicized in real space with the ihrsr himpose program. an initial atomic model was built from the resulting density as described below, and the fourier amplitude of the resulting density map was rescaled by a one - dimensional structure factor (24) which was derived from our initial atomic model. the map was further sharpened by deconvolution of an envelope function with a 60 å 2 b factor .
we used 61, 708 particle segments in our refinement process. each segment has a length of 512 pixels, or 445 å. although a recent paper recommends a large overlap between neighboring segments for objects with small rise per subunit (33), we initially chose an overlapping level of 90% as previously used (2, 9, 32) (si discussion). therefore, each particle segment has 10% (or 51 pixels) of fresh data, which represents 31 asymmetric units. all these segments represent about 1. 9 million asymmetric units, or 31, 882 icosahedral particle equivalents (compare with 20, 473 in ref. 18). bad segments were excluded based on lack of mutual similarity, and about 43, 000 segments (22, 000 icosahedral particle equivalents; compare with 18, 646 in ref. 18) were included in the final reconstruction .
author contributions: p. g. and z. h. z. designed research; p. g. performed research; p. g. and z. h. z. analyzed data; and p. g. and z. h. z. wrote the paper .
data deposition: the cryoem density map and the atomic model have been deposited in the emdb and protein data bank (id codes emd - 5185 and 3j06, respectively) .
structure of tobacco mosaic virus at 3. 6 å resolution: implications for assembly
visualization of protein - nucleic acid interactions in a virus. refined structure of intact tobacco mosaic virus at 2. 9 å resolution by x - ray fiber diffraction
structure of the u2 strain of tobacco mosaic virus refined at 3. 5 å resolution using x - ray fiber diffraction
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researchers used field data from 2012 to 2015 to study mortality and allele frequency changes in the sea star pisaster ochraceus during a mass mortality event in northcentral california, and found that surviving adult and juvenile sea stars experienced 81% mortality and allele shifts, according to the authors .
a survey of more than 4, 600 american adults conducted in 1995 - 1996 and in 2011 - 2014 suggests that among individuals of low socioeconomic status, negative affect increased significantly between the two survey waves, whereas life satisfaction and psychological well - being decreased .
a study of cognitive ability in norwegian males born from 1962 to 1991 suggests that environmental factors rather than changing genetic composition of families likely account for most of the change in norwegian population iq .
the mathematical tools behind recent gerrymandering cases have brought a modicum of precision into the political arena—but this rigor hasn’t always been enough to spur policy changes .
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urltoken is a gaming blog for pc and console gamers who are interested in several genres from rpg to strategy, adventure, and action. we focus on classic computer games but also write articles on xboxone, playstation4 and retro consoles such as nes / snes .
meaning of this library is to give access to browse release date / publisher and game rating info of specific games and link
lets play videos
to them. this list is heavily focused in traditional and modern rpg and adventure games. some of action games are accepted if they: contain adventure or rpg elements, extensive storyline, classic fantasy setting or are survival type of horror action / adventure games (like system shock or grand theft auto for instance which are hybrids). does include some indie rpg' s - i might remove some very minor releases with no info available. this list is by no means perfect, but i aim to include majority of new and old rpg, rpg / adventure, adventure, action / adventure and adventure / puzzle type of games here .
ratings are based on gamespot user average and urltoken average score of all magazines the site knows. more the known game, more reliable score since it' s score is generally based on more reviews. minimum user reviews to be accepted (gamespot): twenty .
what it doesn' t have - - simulations, sports, mmorpg' s (unless tba), straight forward action shooters or fps without adventure element, strategy games in general. any ps3 / xbox360 or other console exclusive games .
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gr = urltoken rating (average out of every game magazine the website knows - gamespot / ign / pcgamer etc. )
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cryo interactive entertainment was a french video game development and publishing company founded in 1992 , but existing unofficially since 1989 as a developer group under the name cryo . 
cryo interactive entertainment was a french video game development and publishing company founded in 1992, but existing unofficially since 1989 as a developer group under the name cryo.
cryo interactive entertainment was a french video game development and publishing company founded in 1992, but existing unofficially since 1989 as a developer group under the name cryo.