<PAGE>   1

      As filed with the Securities and Exchange Commission on May 16, 2000
                                                  REGISTRATION NO. 333 - _____

===============================================================================

                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                              --------------------

                                    FORM S-8

                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933

                                   ----------

                            PER-SE TECHNOLOGIES, INC.
             (Exact name of registrant as specified in its charter)

                  DELAWARE                                 58-1651222
       (State or other jurisdiction of                  (I.R.S. Employer
       incorporation or organization)                  Identification No.)

                           2840 MT. WILKINSON PARKWAY
                             ATLANTA, GEORGIA 30339
   (Address, including zip code, of registrant's principal executive offices)

                            PER-SE TECHNOLOGIES, INC.
               NON-EMPLOYEE DIRECTOR STOCK OPTION PLAN, AS AMENDED
                              (Full title of plan)

                              RANDOLPH L. M. HUTTO
                  EXECUTIVE VICE PRESIDENT AND GENERAL COUNSEL
                           2840 MT. WILKINSON PARKWAY
                             ATLANTA, GEORGIA 30339
                                 (770) 444-5300
                (Name, address, including zip code, and telephone
               number, including area code, of agent for service)


                         CALCULATION OF REGISTRATION FEE


<TABLE>
<CAPTION>

-----------------------------------------------------------------------------------------------------------------
                                                                Proposed Maximum  Proposed Maximum     Amount of
Title of Securities to be Registered              Amount to      Offering Price       Aggregate      Registration
                                                be Registered     Per Share(1)    Offering Price(1)       Fee
-----------------------------------------------------------------------------------------------------------------
<S>                                             <C>             <C>               <C>                <C>
Common Stock, par value $.01 per share........     250,000           $6.84          $1,710,000.00       $451.44
-----------------------------------------------------------------------------------------------------------------
</TABLE>

(1)      Estimated solely for the purpose of computing the registration fee
         pursuant to Rule 457(h) on the basis of the high and low prices of
         Common Stock of Per-Se Technologies, Inc. on May 10, 2000.



<PAGE>   2

================================================================================


                                     PART II

               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

      The contents of the Registrant's Registration Statement on Form S-8, File
Number 33-95746 are incorporated herein by reference.

Item 3. Incorporation of Certain Documents by Reference.

      The following documents previously filed by the Registrant with the
Securities and Exchange Commission are incorporated by reference in this
Registration Statement:

             (a) The Registrant's Annual Report on Form 10-K for the fiscal year
      ended December 31, 1999, filed on March 27, 2000;

             (b) All reports filed by the Registrant pursuant to Section 13(a)
      or 15(d) of the Securities Exchange Act of 1934, as amended (the "Exchange
      Act"), since December 31, 1999;

             (c) The description of the Registrant's common stock, par value
      $.01 per share ("Common Stock"), contained in the Registration Statement
      on Form 8-A/A dated May 22, 1996, and any amendment or report filed for
      the purpose of updating such description; and

             (d) The description of Rights set forth in the Registration
      Statement on Form 8-A filed February 12, 1999, and any amendment or report
      filed for the purpose of updating such description.

      All documents filed by the Registrant subsequent to the date of this
Registration Statement pursuant to Sections 13(a), 13(c), 14 and 15(d) of the
Exchange Act and prior to the filing of a post-effective amendment which
indicates that all securities offered hereunder have been sold or which
deregisters all securities then remaining unsold shall be deemed to be
incorporated by reference in this Registration Statement and to be a part of
this Registration Statement from the date of filing of such documents.

Item 5. Interests of Named Experts and Counsel

         The opinion of counsel as to the legality of the securities registered
hereunder is given by Randolph L. M. Hutto, Executive Vice President, General
Counsel and Secretary of the Registrant. As of the date hereof, Mr. Hutto
beneficially owns approximately 67,556 shares of the Registrant's Common Stock.

Item 6. Indemnification of Directors and Officers

      The following summary is qualified in its entirety by reference to the
complete text of the statute, the Restated Certificate of Incorporation,
Restated By-Laws and agreement referred to below.

      The Registrant's Restated By-Laws provide that each person who was or is
made a party to, is threatened to be made a party to or is otherwise involved in
any action, suit or proceeding, whether civil, criminal, administrative or
investigative, by reason of the fact that he is or was a director, officer,
employee or agent of the Registrant (or is or was serving at the request of the
Registrant as a director, officer, employee or agent of another entity), will be
indemnified and held harmless by the Registrant to the fullest extent permitted
by the Delaware General Corporation Law as it currently exists or is later
amended.



<PAGE>   3

      Under Section 145 of the Delaware General Corporation Law, a corporation
may indemnify a director, officer, employee or agent of the corporation (or
other entity if such person is serving in such capacity at the corporation's
request) against expenses (including attorneys' fees), judgments, fines and
amounts paid in settlement actually and reasonably incurred by him if he acted
in good faith and in a manner he reasonably believed to be in, or not opposed
to, the best interests of the corporation and, with respect to any criminal
action or proceeding, had no reasonable cause to believe his conduct was
unlawful. In the case of an action brought by or in the right of the
corporation, the corporation may indemnify a director, officer, employee or
agent of the corporation (or other entity if such person is serving in such
capacity at the corporation's request) against expenses (including attorneys'
fees) actually and reasonably incurred by him if he acted in good faith and in a
manner he reasonably believed to be in, or not opposed to, the best interests of
the corporation, except that no indemnification shall be made in respect of any
claim, issue or matter as to which such persons shall have been adjudged to be
liable to the corporation unless a court determines that, despite the
adjudication of liability but in view of all the circumstances of the case, such
person is fairly and reasonably entitled to indemnification for such expenses as
the court shall deem proper. Expenses (including attorneys' fees) incurred by an
officer or director in defending any civil, criminal, administrative or
investigative action, suit or proceeding may be paid by the corporation in
advance of the final disposition of such action, suit or proceeding upon receipt
of an undertaking by or on behalf of such director or officer to repay such
amount if it shall ultimately be determined that he is not entitled to be
indemnified by the corporation.

      The Registrant's Restated Certificate of Incorporation provides that a
director of the Registrant shall not be personally liable to the Registrant or
its stockholders for monetary damages for breach of fiduciary duty as a
director, except for liability (i) for any breach of the director's duty of
loyalty to the Registrant or its stockholders, (ii) for any acts or omissions
not in good faith or which involve intentional misconduct or a knowing violation
of law, (iii) under Section 174 of the Delaware General Corporation Law or (iv)
for any transaction in which the director derived an improper personal benefit.

      In addition, the Registrant and David E. McDowell are parties to an
agreement pursuant to which the Registrant has agreed to indemnify and hold
harmless Mr. McDowell to the fullest extent permitted by the Delaware General
Corporation Law as it presently exists or to such greater extent as such law may
subsequently be amended.

      The Registrant maintains directors and officers liability insurance. Such
policies have a deductible of $150,000 and an annual per occurrence and
aggregate cap on coverage of $50 million.

Item 8.      Exhibits.

<TABLE>
<CAPTION>
Exhibit             Description
-------             -----------

<S>                 <C>
4.1                 Restated Certificate of Incorporation of Registrant (incorporated by reference to Exhibit 3.1
                    to Annual Report on Form 10-K for the year ended December 31, 1999).

4.2                 Restated By-Laws of Registrant (incorporated  by reference to Exhibit 3.2 to Annual Report on
                    Form 10-K for the year ended December 31, 1999).

4.3                 Specimen Common Stock Certificate (incorporated by reference to Exhibit 4.1 to Annual Report
                    on Form 10-K for the year ended December 31, 1999).

4.4                 Rights Agreement dated as of February 11, 1999, between Registrant and American Stock Transfer &
                    Trust Company (including form of rights certificates) (incorporated by reference to Exhibit 4
                    to Current Report on Form 8-K filed on February 12, 1999).

4.5                 First Amendment to Rights Agreement dated as of February 11, 1999, between Registrant and
                    American Stock Transfer & Trust Company, entered into as of May 4, 2000 (incorporated by
                    reference to Exhibit 4.4 to Quarterly Report on Form 10-Q for the quarter ended March 31,
                    2000).
</TABLE>




                                      -3-
<PAGE>   4

<TABLE>
<S>                 <C>
5                   Opinion of Randolph L. M. Hutto, Esq. regarding the legality of shares being registered.

23.1                Consent of PricewaterhouseCoopers LLP

99.1                Form of Option Agreement relating to Registrant's Non-Employee Director Stock Option Plan
                    (incorporated by reference to Exhibit 4.5 to Annual Report on Form 10-K for the year
                    ended December 31, 1999).

99.2                Registrant's Non-Employee Director Stock Option Plan, dated as of August 12, 1994
                    (incorporated by reference to Exhibit 10.2 to Quarterly Report on Form 10-Q for the
                    quarter ended September 30, 1994).

99.3                First Amendment to Registrant's Non-Employee Director Stock Option Plan (incorporated
                    by reference to Exhibit 10.25 to Annual Report on Form 10-K for the year ended
                    December 31, 1998).

99.4                Second Amendment to Registrant's Non-Employee Director Stock Option Plan (incorporated
                    by reference to Exhibit 10.1 to Quarterly Report on Form 10-Q for the quarter ended
                    March 31, 1999).

99.5                Third Amendment to Registrant's Non-Employee Director Stock Option Plan (incorporated
                    by reference to Exhibit 10.16 to Annual Report on Form 10-K for the year ended
                    December 31, 1999).

99.6                Fourth Amendment to Registrant's Non-Employee Director Stock Option Plan (incorporated
                    by reference to Exhibit 10.46 to Annual Report on Form 10-K for the year ended
                    December  31, 1999).
</TABLE>



                                   SIGNATURES


      Pursuant to the requirements of the Securities Act of 1933, Per-Se
Technologies, Inc. certifies that it has reasonable grounds to believe that it
meets all of the requirements for filing on Form S-8 and has duly caused this
Registration Statement to be signed on its behalf by the undersigned, thereunto
duly authorized, in the City of Atlanta, State of Georgia, on this 16th day of
May, 2000.


                                      PER-SE TECHNOLOGIES, INC.



                                      By:   /s/ ALLEN W. RITCHIE
                                         ---------------------------
                                            Allen W. Ritchie
                                            President and
                                            Chief Executive Officer

                                      -4-


<PAGE>   5

      Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed by the following persons in the
capacities and on the dates indicated.

<TABLE>
<CAPTION>
Signature                                         Title                                     Date

<S>                                               <C>                                       <C>
 /s/ DAVID E. MCDOWELL                            Chairman and Director                     May 16, 2000
-------------------------------------
David E. McDowell



 /s/ ALLEN W. RITCHIE                             President, Chief Executive                May 16, 2000
-------------------------------------             Officer and Director
Allen W. Ritchie



 /s/ WAYNE A. TANNER                              Executive Vice President and              May 16, 2000
-------------------------------------             Chief Financial Officer
Wayne A. Tanner



 /s/ MARY C. BLACKADAR                            Vice President and Controller             May 16, 2000
-------------------------------------             (Principal Accounting Officer)
Mary C. Blackadar



 /s/ RODERICK M. HILLS                            Director                                  May 16, 2000
-------------------------------------
Roderick M. Hills



 /s/ DAVID R. HOLBROOKE                           Director                                  May 16, 2000
-------------------------------------
David R. Holbrooke, M.D.



 /s/ KEVIN E. MOLEY                               Director                                  May 16, 2000
-------------------------------------
Kevin E. Moley



 /s/ JOHN C. POPE                                 Director                                  May 16, 2000
-------------------------------------
John C. Pope



 /s/ C. CHRISTOPHER TROWER                        Director                                  May 16, 2000
-------------------------------------
C. Christopher Trower
</TABLE>



<PAGE>   6

                                  EXHIBIT INDEX

<TABLE>
<CAPTION>
Exhibit                                   Description                                             Page
-------                                   -----------                                             ----

<S>               <C>                                                                             <C>
4.1               Restated Certificate of Incorporation of Registrant
                  (incorporated by reference to Exhibit 3.1 to Annual Report on
                  Form 10-K for the year ended December 31, 1999).

4.2               Restated By-Laws of Registrant (incorporated by reference to
                  Exhibit 3.2 to Annual Report on Form 10-K for the year ended
                  December 31, 1999).

4.3               Specimen Common Stock Certificate (incorporated by reference
                  to Exhibit 4.1 to Annual Report on Form 10-K for the year
                  ended December 31, 1999).

4.4               Rights Agreement dated as of February 11, 1999, between
                  Registrant and American Stock Transfer & Trust Company
                  (including form of rights certificates) (incorporated by
                  reference to Exhibit 4 to Current Report on Form 8-K filed on
                  February 12, 1999).

4.5               First Amendment to Rights Agreement dated as of February 11,
                  1999, between Registrant and American Stock Transfer & Trust
                  Company, entered into as of May 4, 2000 (incorporated by
                  reference to Exhibit 4.4 to Quarterly Report on Form 10-Q for
                  the quarter ended March 31, 2000).

5                 Opinion of Randolph L. M. Hutto, Esq. regarding the legality
                  of shares being registered.

23.1              Consent of PricewaterhouseCoopers LLP

99.1              Form of Option Agreement relating to Registrant's Non-Employee
                  Director Stock Option Plan (incorporated by reference to
                  Exhibit 4.5 to Annual Report on Form 10-K for the year ended
                  December 31, 1999).

99.2              Registrant's Non-Employee Director Stock Option Plan, dated as
                  of August 12, 1994 (incorporated by reference to Exhibit 10.2
                  to Quarterly Report on Form 10-Q for the quarter ended
                  September 30, 1994).

99.3              First Amendment to Registrant's Non-Employee Director Stock
                  Option Plan (incorporated by reference to Exhibit 10.25 to
                  Annual Report on Form 10-K for the year ended December 31,
                  1998).

99.4              Second Amendment to Registrant's Non-Employee Director Stock
                  Option Plan (incorporated by reference to Exhibit 10.1 to
                  Quarterly Report on Form 10-Q for the quarter ended March 31,
                  1999).

99.5              Third Amendment to Registrant's Non-Employee Director Stock
                  Option Plan (incorporated by reference to Exhibit 10.16 to
                  Annual Report on Form 10-K for the year ended December 31,
                  1999).

99.6              Fourth Amendment to Registrant's Non-Employee Director Stock
                  Option Plan (incorporated by reference to Exhibit 10.46 to
                  Annual Report on Form 10-K for the year ended December 31,
                  1999).
</TABLE>
[{"type": "S-8", "sequence": "1", "description": "PER-SE TECHNOLOGIES, INC.", "secsgml_size_bytes": 18851}]
{"company-data": {"conformed-name": "PER SE TECHNOLOGIES INC", "cik": "0000878556", "assigned-sic": "7374", "irs-number": "581651222", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-37152", "film-number": "637744"}, "business-address": {"street1": "2840 MT WILKINSON PARKWAY", "street2": "SUITE 300", "city": "ATLANTA", "state": "GA", "zip": "30339", "phone": "7704445300"}, "mail-address": {"street1": "2700 CUMBERLAND PKWY", "street2": "STE 300", "city": "ATLANTA", "state": "GA", "zip": "30339"}, "former-company": {"former-conformed-name": "MEDAPHIS CORP", "date-changed": "19931027"}}
1

      As filed with the Securities and Exchange Commission on May 16, 2000
                                                  REGISTRATION NO. 333 - _____

===============================================================================

                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                              --------------------

                                    FORM S-8

                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933

                                   ----------

                            PER-SE TECHNOLOGIES, INC.
             (Exact name of registrant as specified in its charter)

                  DELAWARE                                 58-1651222
       (State or other jurisdiction of                  (I.R.S. Employer
       incorporation or organization)                  Identification No.)

                           2840 MT. WILKINSON PARKWAY
                             ATLANTA, GEORGIA 30339
   (Address, including zip code, of registrant's principal executive offices)

                            PER-SE TECHNOLOGIES, INC.
               NON-EMPLOYEE DIRECTOR STOCK OPTION PLAN, AS AMENDED
                              (Full title of plan)

                              RANDOLPH L. M. HUTTO
                  EXECUTIVE VICE PRESIDENT AND GENERAL COUNSEL
                           2840 MT. WILKINSON PARKWAY
                             ATLANTA, GEORGIA 30339
                                 (770) 444-5300
                (Name, address, including zip code, and telephone
               number, including area code, of agent for service)

                         CALCULATION OF REGISTRATION FEE
-----------------------------------------------------------------------------------------------------------------
                                                                Proposed Maximum  Proposed Maximum     Amount of
Title of Securities to be Registered              Amount to      Offering Price       Aggregate      Registration
                                                be Registered     Per Share(1)    Offering Price(1)       Fee
-----------------------------------------------------------------------------------------------------------------
Common Stock, par value $.01 per share........     250,000           $6.84          $1,710,000.00       $451.44
-----------------------------------------------------------------------------------------------------------------
(1)      Estimated solely for the purpose of computing the registration fee
         pursuant to Rule 457(h) on the basis of the high and low prices of
         Common Stock of Per-Se Technologies, Inc. on May 10, 2000.
2

================================================================================

                                     PART II

               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

      The contents of the Registrant's Registration Statement on Form S-8, File
Number 33-95746 are incorporated herein by reference.

Item 3. Incorporation of Certain Documents by Reference.

      The following documents previously filed by the Registrant with the
Securities and Exchange Commission are incorporated by reference in this
Registration Statement:

             (a) The Registrant's Annual Report on Form 10-K for the fiscal year
      ended December 31, 1999, filed on March 27, 2000;

             (b) All reports filed by the Registrant pursuant to Section 13(a)
      or 15(d) of the Securities Exchange Act of 1934, as amended (the "Exchange
      Act"), since December 31, 1999;

             (c) The description of the Registrant's common stock, par value
      $.01 per share ("Common Stock"), contained in the Registration Statement
      on Form 8-A/A dated May 22, 1996, and any amendment or report filed for
      the purpose of updating such description; and

             (d) The description of Rights set forth in the Registration
      Statement on Form 8-A filed February 12, 1999, and any amendment or report
      filed for the purpose of updating such description.

      All documents filed by the Registrant subsequent to the date of this
Registration Statement pursuant to Sections 13(a), 13(c), 14 and 15(d) of the
Exchange Act and prior to the filing of a post-effective amendment which
indicates that all securities offered hereunder have been sold or which
deregisters all securities then remaining unsold shall be deemed to be
incorporated by reference in this Registration Statement and to be a part of
this Registration Statement from the date of filing of such documents.

Item 5. Interests of Named Experts and Counsel

         The opinion of counsel as to the legality of the securities registered
hereunder is given by Randolph L. M. Hutto, Executive Vice President, General
Counsel and Secretary of the Registrant. As of the date hereof, Mr. Hutto
beneficially owns approximately 67,556 shares of the Registrant's Common Stock.

Item 6. Indemnification of Directors and Officers

      The following summary is qualified in its entirety by reference to the
complete text of the statute, the Restated Certificate of Incorporation,
Restated By-Laws and agreement referred to below.

      The Registrant's Restated By-Laws provide that each person who was or is
made a party to, is threatened to be made a party to or is otherwise involved in
any action, suit or proceeding, whether civil, criminal, administrative or
investigative, by reason of the fact that he is or was a director, officer,
employee or agent of the Registrant (or is or was serving at the request of the
Registrant as a director, officer, employee or agent of another entity), will be
indemnified and held harmless by the Registrant to the fullest extent permitted
by the Delaware General Corporation Law as it currently exists or is later
amended.
3

      Under Section 145 of the Delaware General Corporation Law, a corporation
may indemnify a director, officer, employee or agent of the corporation (or
other entity if such person is serving in such capacity at the corporation's
request) against expenses (including attorneys' fees), judgments, fines and
amounts paid in settlement actually and reasonably incurred by him if he acted
in good faith and in a manner he reasonably believed to be in, or not opposed
to, the best interests of the corporation and, with respect to any criminal
action or proceeding, had no reasonable cause to believe his conduct was
unlawful. In the case of an action brought by or in the right of the
corporation, the corporation may indemnify a director, officer, employee or
agent of the corporation (or other entity if such person is serving in such
capacity at the corporation's request) against expenses (including attorneys'
fees) actually and reasonably incurred by him if he acted in good faith and in a
manner he reasonably believed to be in, or not opposed to, the best interests of
the corporation, except that no indemnification shall be made in respect of any
claim, issue or matter as to which such persons shall have been adjudged to be
liable to the corporation unless a court determines that, despite the
adjudication of liability but in view of all the circumstances of the case, such
person is fairly and reasonably entitled to indemnification for such expenses as
the court shall deem proper. Expenses (including attorneys' fees) incurred by an
officer or director in defending any civil, criminal, administrative or
investigative action, suit or proceeding may be paid by the corporation in
advance of the final disposition of such action, suit or proceeding upon receipt
of an undertaking by or on behalf of such director or officer to repay such
amount if it shall ultimately be determined that he is not entitled to be
indemnified by the corporation.

      The Registrant's Restated Certificate of Incorporation provides that a
director of the Registrant shall not be personally liable to the Registrant or
its stockholders for monetary damages for breach of fiduciary duty as a
director, except for liability (i) for any breach of the director's duty of
loyalty to the Registrant or its stockholders, (ii) for any acts or omissions
not in good faith or which involve intentional misconduct or a knowing violation
of law, (iii) under Section 174 of the Delaware General Corporation Law or (iv)
for any transaction in which the director derived an improper personal benefit.

      In addition, the Registrant and David E. McDowell are parties to an
agreement pursuant to which the Registrant has agreed to indemnify and hold
harmless Mr. McDowell to the fullest extent permitted by the Delaware General
Corporation Law as it presently exists or to such greater extent as such law may
subsequently be amended.

      The Registrant maintains directors and officers liability insurance. Such
policies have a deductible of $150,000 and an annual per occurrence and
aggregate cap on coverage of $50 million.

Item 8.      Exhibits.
Exhibit             Description
-------             -----------
4.1                 Restated Certificate of Incorporation of Registrant (incorporated by reference to Exhibit 3.1
                    to Annual Report on Form 10-K for the year ended December 31, 1999).

4.2                 Restated By-Laws of Registrant (incorporated  by reference to Exhibit 3.2 to Annual Report on
                    Form 10-K for the year ended December 31, 1999).

4.3                 Specimen Common Stock Certificate (incorporated by reference to Exhibit 4.1 to Annual Report
                    on Form 10-K for the year ended December 31, 1999).

4.4                 Rights Agreement dated as of February 11, 1999, between Registrant and American Stock Transfer &
                    Trust Company (including form of rights certificates) (incorporated by reference to Exhibit 4
                    to Current Report on Form 8-K filed on February 12, 1999).

4.5                 First Amendment to Rights Agreement dated as of February 11, 1999, between Registrant and
                    American Stock Transfer & Trust Company, entered into as of May 4, 2000 (incorporated by
                    reference to Exhibit 4.4 to Quarterly Report on Form 10-Q for the quarter ended March 31,
                    2000).
-3-
4
5                   Opinion of Randolph L. M. Hutto, Esq. regarding the legality of shares being registered.

23.1                Consent of PricewaterhouseCoopers LLP

99.1                Form of Option Agreement relating to Registrant's Non-Employee Director Stock Option Plan
                    (incorporated by reference to Exhibit 4.5 to Annual Report on Form 10-K for the year
                    ended December 31, 1999).

99.2                Registrant's Non-Employee Director Stock Option Plan, dated as of August 12, 1994
                    (incorporated by reference to Exhibit 10.2 to Quarterly Report on Form 10-Q for the
                    quarter ended September 30, 1994).

99.3                First Amendment to Registrant's Non-Employee Director Stock Option Plan (incorporated
                    by reference to Exhibit 10.25 to Annual Report on Form 10-K for the year ended
                    December 31, 1998).

99.4                Second Amendment to Registrant's Non-Employee Director Stock Option Plan (incorporated
                    by reference to Exhibit 10.1 to Quarterly Report on Form 10-Q for the quarter ended
                    March 31, 1999).

99.5                Third Amendment to Registrant's Non-Employee Director Stock Option Plan (incorporated
                    by reference to Exhibit 10.16 to Annual Report on Form 10-K for the year ended
                    December 31, 1999).

99.6                Fourth Amendment to Registrant's Non-Employee Director Stock Option Plan (incorporated
                    by reference to Exhibit 10.46 to Annual Report on Form 10-K for the year ended
                    December  31, 1999).
SIGNATURES

      Pursuant to the requirements of the Securities Act of 1933, Per-Se
Technologies, Inc. certifies that it has reasonable grounds to believe that it
meets all of the requirements for filing on Form S-8 and has duly caused this
Registration Statement to be signed on its behalf by the undersigned, thereunto
duly authorized, in the City of Atlanta, State of Georgia, on this 16th day of
May, 2000.

                                      PER-SE TECHNOLOGIES, INC.

                                      By:   /s/ ALLEN W. RITCHIE
                                         ---------------------------
                                            Allen W. Ritchie
                                            President and
                                            Chief Executive Officer

                                      -4-
5

      Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed by the following persons in the
capacities and on the dates indicated.
Signature                                         Title                                     Date
/s/ DAVID E. MCDOWELL                            Chairman and Director                     May 16, 2000
-------------------------------------
David E. McDowell

 /s/ ALLEN W. RITCHIE                             President, Chief Executive                May 16, 2000
-------------------------------------             Officer and Director
Allen W. Ritchie

 /s/ WAYNE A. TANNER                              Executive Vice President and              May 16, 2000
-------------------------------------             Chief Financial Officer
Wayne A. Tanner

 /s/ MARY C. BLACKADAR                            Vice President and Controller             May 16, 2000
-------------------------------------             (Principal Accounting Officer)
Mary C. Blackadar

 /s/ RODERICK M. HILLS                            Director                                  May 16, 2000
-------------------------------------
Roderick M. Hills

 /s/ DAVID R. HOLBROOKE                           Director                                  May 16, 2000
-------------------------------------
David R. Holbrooke, M.D.

 /s/ KEVIN E. MOLEY                               Director                                  May 16, 2000
-------------------------------------
Kevin E. Moley

 /s/ JOHN C. POPE                                 Director                                  May 16, 2000
-------------------------------------
John C. Pope

 /s/ C. CHRISTOPHER TROWER                        Director                                  May 16, 2000
-------------------------------------
C. Christopher Trower
6

                                  EXHIBIT INDEX
Exhibit                                   Description                                             Page
-------                                   -----------                                             ----
4.1               Restated Certificate of Incorporation of Registrant
                  (incorporated by reference to Exhibit 3.1 to Annual Report on
                  Form 10-K for the year ended December 31, 1999).

4.2               Restated By-Laws of Registrant (incorporated by reference to
                  Exhibit 3.2 to Annual Report on Form 10-K for the year ended
                  December 31, 1999).

4.3               Specimen Common Stock Certificate (incorporated by reference
                  to Exhibit 4.1 to Annual Report on Form 10-K for the year
                  ended December 31, 1999).

4.4               Rights Agreement dated as of February 11, 1999, between
                  Registrant and American Stock Transfer & Trust Company
                  (including form of rights certificates) (incorporated by
                  reference to Exhibit 4 to Current Report on Form 8-K filed on
                  February 12, 1999).

4.5               First Amendment to Rights Agreement dated as of February 11,
                  1999, between Registrant and American Stock Transfer & Trust
                  Company, entered into as of May 4, 2000 (incorporated by
                  reference to Exhibit 4.4 to Quarterly Report on Form 10-Q for
                  the quarter ended March 31, 2000).

5                 Opinion of Randolph L. M. Hutto, Esq. regarding the legality
                  of shares being registered.

23.1              Consent of PricewaterhouseCoopers LLP

99.1              Form of Option Agreement relating to Registrant's Non-Employee
                  Director Stock Option Plan (incorporated by reference to
                  Exhibit 4.5 to Annual Report on Form 10-K for the year ended
                  December 31, 1999).

99.2              Registrant's Non-Employee Director Stock Option Plan, dated as
                  of August 12, 1994 (incorporated by reference to Exhibit 10.2
                  to Quarterly Report on Form 10-Q for the quarter ended
                  September 30, 1994).

99.3              First Amendment to Registrant's Non-Employee Director Stock
                  Option Plan (incorporated by reference to Exhibit 10.25 to
                  Annual Report on Form 10-K for the year ended December 31,
                  1998).

99.4              Second Amendment to Registrant's Non-Employee Director Stock
                  Option Plan (incorporated by reference to Exhibit 10.1 to
                  Quarterly Report on Form 10-Q for the quarter ended March 31,
                  1999).

99.5              Third Amendment to Registrant's Non-Employee Director Stock
                  Option Plan (incorporated by reference to Exhibit 10.16 to
                  Annual Report on Form 10-K for the year ended December 31,
                  1999).

99.6              Fourth Amendment to Registrant's Non-Employee Director Stock
                  Option Plan (incorporated by reference to Exhibit 10.46 to
                  Annual Report on Form 10-K for the year ended December 31,
                  1999).