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<DIV align="center" style="font-size: 10pt; margin-top: 18pt">As filed with the Securities and Exchange Commission on June&nbsp;30, 2006
</DIV>


<DIV align="right" style="font-size: 10pt; margin-top: 6pt">Registration No.&nbsp;333-
</DIV>

<DIV align="center" style="font-size: 14pt; margin-top: 6pt"><B>SECURITIES AND EXCHANGE COMMISSION</B>
</DIV>

<DIV align="center" style="font-size: 12pt"><B>Washington, D. C. 20549</B>
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<DIV style="font-size: 3pt; margin-top: 12pt; width: 26%; border-top: 1px solid #000000">&nbsp;</DIV>
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<DIV align="center" style="font-size: 12pt; margin-top: 12pt"><B>FORM S-8</B>
</DIV>

<DIV align="center" style="font-size: 12pt"><B>REGISTRATION STATEMENT<BR>
UNDER<BR>
THE SECURITIES ACT OF 1933</B>
</DIV>


<DIV align="center">
<DIV style="font-size: 3pt; margin-top: 12pt; width: 26%; border-top: 1px solid #000000">&nbsp;</DIV>
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<DIV align="center" style="font-size: 24pt; margin-top: 12pt"><B>TRIPATH IMAGING, INC.</B>
</DIV>

<DIV align="center" style="font-size: 10pt">(Exact Name of Registrant as Specified in Its Charter)
</DIV>

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<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
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    <TD width="45%">&nbsp;</TD>
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<TR valign="bottom">
    <TD align="center" valign="top"><B>Delaware</B>
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top"><B>56-1995728</B></TD>
</TR>
<TR valign="bottom">
    <TD align="center" valign="top">(State or Other Jurisdiction of
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">(I.R.S. Employer</TD>
</TR>
<TR valign="bottom">
    <TD align="center" valign="top">Incorporation or Organization)
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">Identification No.)</TD>
</TR>
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<DIV align="center" style="font-size: 10pt; margin-top: 12pt"><B>780 Plantation Drive<BR>
Burlington, North Carolina 27215</B><BR>
(Address of Principal Executive Offices)
</DIV>


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<DIV style="font-size: 3pt; margin-top: 12pt; width: 26%; border-top: 1px solid #000000">&nbsp;</DIV>
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<DIV align="center" style="font-size: 10pt; margin-top: 12pt"><B>AMENDED AND RESTATED 1997 DIRECTOR EQUITY PLAN<BR>
(formerly entitled 1997 Director Stock Option Plan)</B><BR>
(Full Title of the Plan)
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 12pt"><B>PAUL R. SOHMER, M.D.<BR>
PRESIDENT AND CHIEF EXECUTIVE OFFICER</B><BR>
TriPath Imaging, Inc.<BR>
780 Plantation Drive<BR>
Burlington, North Carolina 27215<BR>
(336)&nbsp;222-9707<BR>
(Name, Address and Telephone Number of Agent for Service)
</DIV>


<DIV align="center">
<DIV style="font-size: 3pt; margin-top: 12pt; width: 26%; border-top: 1px solid #000000">&nbsp;</DIV>
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<DIV align="center" style="font-size: 10pt; margin-top: 12pt">with copies to:
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 12pt"><B>JAMES T. BARRETT, ESQ.</B><BR>
Edwards Angell Palmer &#038; Dodge LLP<BR>
111 Huntington Avenue<BR>
Boston, Massachusetts 02199<BR>
(617)&nbsp;239-0100
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 12pt"><B>CALCULATION OF REGISTRATION FEE</B>
</DIV>

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    <TD width="54%">&nbsp;</TD>
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    <TD width="2%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="2%">&nbsp;</TD><!-- VRule -->
    <TD width="2%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="2%">&nbsp;</TD><!-- VRule -->
    <TD width="2%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="2%">&nbsp;</TD><!-- VRule -->
    <TD width="2%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>

    <TD width="1%">&nbsp;</TD>
</TR><TR style="font-size: 1px" valign="bottom">
    <TD nowrap align="left" colspan="23" style="border-bottom: 1px double #000000">&nbsp;</TD>
</TR>
<TR style="font-size: 8pt" valign="bottom">    <TD width="1%">&nbsp;</TD>

    <TD>&nbsp;</TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Proposed Maximum</B></TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Proposed Maximum</B></TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
</TR>
<TR style="font-size: 8pt" valign="bottom">    <TD width="1%">&nbsp;</TD>

    <TD nowrap align="left"><B>Title Of Securities</B></TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Amount To Be</B></TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Offering Price Per</B></TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Aggregate Offering</B></TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Amount of</B></TD>
    <TD width="1%">&nbsp;</TD>
</TR>
<TR style="font-size: 8pt" valign="bottom">    <TD width="1%">&nbsp;</TD>

    <TD nowrap align="left"><B>To Be Registered</B></TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Registered(1)(2)</B></TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Share(3)</B></TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Price(3)</B></TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Registration Fee</B></TD>
    <TD width="1%">&nbsp;</TD>
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    <TD width="1%" style="border-top: 1px solid #000000">&nbsp;</TD>
                    <TD style="border-top: 1px solid #000000"><DIV style="margin-left:15px; text-indent:-15px">Common Stock, $0.01 par value</DIV></TD>
    <TD style="border-right: 1px solid #000000; border-top: 1px solid #000000">&nbsp;</TD>
    <TD style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD nowrap colspan="3" align="center" style="border-top: 1px solid #000000">150,000 shares</TD>
    <TD style="border-right: 1px solid #000000; border-top: 1px solid #000000">&nbsp;</TD>
    <TD style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD align="right" style="border-top: 1px solid #000000">$</TD>
    <TD align="right" style="border-top: 1px solid #000000">6.52</TD>
    <TD style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD style="border-right: 1px solid #000000; border-top: 1px solid #000000">&nbsp;</TD>
    <TD style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD align="right" style="border-top: 1px solid #000000">$</TD>
    <TD align="right" style="border-top: 1px solid #000000">978,000</TD>
    <TD style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD style="border-right: 1px solid #000000; border-top: 1px solid #000000">&nbsp;</TD>
    <TD style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD align="right" style="border-top: 1px solid #000000">$</TD>
    <TD align="right" style="border-top: 1px solid #000000">105</TD>
    <TD style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD width="1%" style="border-top: 1px solid #000000">&nbsp;</TD>
</TR>
<TR style="font-size: 1px" valign="bottom">
    <TD nowrap align="left" colspan="23" style="border-top: 1px double #000000">&nbsp;</TD>
</TR>

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<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">(1)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Pursuant to Rule&nbsp;416 under the Securities Act of 1933, to the extent additional shares of our
Common Stock may be issued or issuable as a result of a stock split or other distribution
declared at any time by our Board of Directors while this Registration Statement is in effect,
this Registration Statement is hereby deemed to cover all such additional shares of Common
Stock.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">(2)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>This Registration Statement registers an additional 150,000 shares issuable under our Amended
and Restated 1997 Director Equity Plan (the &#147;Plan&#148;). We have previously registered 450,000
shares issuable under the Plan (Registration Statement No.&nbsp;333-41467, Registration Statement
No.&nbsp;333-74936 and Registration Statement No.&nbsp;333-116274).</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">(3)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Estimated solely for the purpose of determining the registration fee and computed pursuant to
Rule 457(c) and Rule&nbsp;457(h)(1) and based upon the average of the high and low sale prices on
June&nbsp;26, 2006 as reported by the Nasdaq National Market.</TD>
</TR>

</TABLE>
</DIV>
<P align="center" style="font-size: 10pt">&nbsp;
</DIV>

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<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">



</TABLE>
</DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>Part II</B>
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 11pt"><B>INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 12pt">Statement regarding incorporation by reference from effective registration statements:
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;This Registration Statement registers additional securities of the same class as other
securities for which registration statements filed on Forms S-8 relating to our Amended and
Restated 1997 Director Equity Plan (the &#147;Plan&#148;) are already effective. Pursuant to Instruction E
to Form S-8, we incorporate by reference into this Registration Statement the contents of the
registration statements we filed on Forms S-8 (File Nos. 333-41467, 333-74936 and 333-116274) with
the Securities and Exchange Commission on December&nbsp;4, 1997, December&nbsp;12, 2001 and June&nbsp;8, 2004 in
their entirety and including exhibits thereto, relating to the registration of 100,000, 200,000 and
150,000 shares of our Common Stock, $0.01 par value per share, respectively, authorized for
issuance under the Plan. This Registration Statement provides for the registration of an
additional 150,000 shares of Common Stock to be issued under the Plan.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>Item&nbsp;8. Exhibits.</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;See Exhibit&nbsp;Index immediately following the signature page.
</DIV>

<P align="center" style="font-size: 10pt">&nbsp;
</DIV>

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<DIV style="font-family: 'Times New Roman',Times,serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>SIGNATURES</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it
has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and
has duly caused this Registration Statement to be signed on its behalf by the undersigned,
thereunto duly authorized, in the City of Burlington, North Carolina, on this 29th day of June
2006.
</DIV>
<DIV align="center">
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    <TD width="50%">&nbsp;</TD>
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    <TD width="2%">&nbsp;</TD>
    <TD width="40%">&nbsp;</TD>
</TR>
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<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD colspan="3" align="left" valign="top"><B>TRIPATH IMAGING, INC.</B></TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">By:
</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">/s/ Paul R. Sohmer, M.D.</TD>
</TR>
<TR style="font-size: 1px">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top" style="border-top: 1px solid #000000">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Paul R. Sohmer, M.D.<BR>
President and Chief Executive Officer</TD>
</TR>
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</TABLE>
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>POWER OF ATTORNEY</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;We, the undersigned officers and directors of TriPath Imaging, Inc., hereby severally
constitute and appoint Paul R. Sohmer, Stephen P. Hall and James T. Barrett, and each of them
singly, our true and lawful attorneys-in-fact, with full power to them in any and all capacities,
to sign any and all amendments to this Registration Statement on Form S-8 including any
post-effective amendments thereto, and to file the same, with exhibits thereto and other documents
in connection therewith, with the Securities and Exchange Commission, hereby ratifying and
confirming all that each of said attorneys-in-fact may do or cause to be done by virtue hereof.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has
been signed below by the following persons in the capacities and on the dates indicated:
</DIV>
<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
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<TR valign="bottom">
    <TD width="30%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="50%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="10%">&nbsp;</TD>
</TR>
<TR style="font-size: 8pt" valign="bottom">
    <TD nowrap align="center" style="border-bottom: 1px solid #000000"><B>Signature</B></TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" style="border-bottom: 1px solid #000000"><B>Title</B></TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" style="border-bottom: 1px solid #000000"><B>Date</B></TD>
</TR>

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<TR valign="bottom">
    <TD align="center" nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom" style="padding-top: 1em">
    <TD align="center" nowrap valign="top">/s/ Paul R. Sohmer, M.D.
<DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
Paul R. Sohmer, M.D.</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">
President, Chief Executive Officer
and Chairman of the Board
(Principal Executive Officer)
</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">June 29, 2006</TD>
</TR>
<TR valign="bottom" style="padding-top: 1em">
    <TD align="center" nowrap valign="top">/s/ Stephen P. Hall
<DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
Stephen P. Hall</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">
Senior Vice-President and Chief
Financial Officer
(Principal Financial Officer and
Principal Accounting Officer)
</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">June 29, 2006</TD>
</TR>
<TR valign="bottom" style="padding-top: 1em">
    <TD align="center" nowrap valign="top">&nbsp;<BR>
<DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
Haywood D. Cochrane, Jr.</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">
Director
</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">June 29, 2006</TD>
</TR>
<TR valign="bottom" style="padding-top: 1em">
    <TD align="center" nowrap valign="top">/s/ Robert E. Curry, Ph.D.
<DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
Robert E. Curry, Ph.D.</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">
Director
</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">June 29, 2006</TD>
</TR>
<TR valign="bottom" style="padding-top: 1em">
    <TD align="center" nowrap valign="top">/s/ Richard A. Franco, R. Ph.
<DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
Richard A. Franco, R. Ph</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">
Director
</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">June 29, 2006</TD>
</TR>
<TR valign="bottom" style="padding-top: 1em">
    <TD align="center" nowrap valign="top">/s/ Arthur T. King, Ph.D.
<DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
Arthur T. King, Ph.D.</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">
Director
</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">June 29, 2006</TD>
</TR>
<TR valign="bottom" style="padding-top: 1em">
    <TD align="center" nowrap valign="top">/s/ Gail F. Lieberman
<DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
Gail F. Lieberman</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">
Director
</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">June 29, 2006</TD>
</TR>
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</TABLE>
</DIV>


<P align="center" style="font-size: 10pt">&nbsp;
</DIV>

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<DIV style="font-family: 'Times New Roman',Times,serif">


<DIV align="center" style="font-size: 10pt; margin-top: 12pt"><U><B>EXHIBIT INDEX</B></U>
</DIV>

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="12%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="83%">&nbsp;</TD>
</TR>
<TR style="font-size: 8pt" valign="bottom">
    <TD nowrap align="center" style="border-bottom: 1px solid #000000">Exhibit Number</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" style="border-bottom: 1px solid #000000">Description</TD>
</TR>

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<TR>
        <TD>&nbsp;<BR></TD>
</TR>
<TR valign="bottom">
    <TD valign="top" align="center"><DIV style="margin-left:0px; text-indent:-0px">4.1
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Restated Certificate of Incorporation of the Registrant. Filed as
Exhibit&nbsp;3.1 to the Registrant&#146;s Quarterly Report on Form&nbsp;10-Q for the
quarter ended June&nbsp;30, 2002 (File No.&nbsp;0-22885) and incorporated herein
by reference.</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top" align="center"><DIV style="margin-left:0px; text-indent:-0px">4.2
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Amended and Restated By-laws of the Registrant. Filed as Exhibit&nbsp;3.2 to
the Registrant&#146;s Quarterly Report on Form&nbsp;10-Q for the quarter ended
June&nbsp;30, 2002 (File No.&nbsp;0-22885) and incorporated herein by reference.</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top" align="center"><DIV style="margin-left:0px; text-indent:-0px">5.1
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Opinion of Edwards Angell Palmer &#038; Dodge LLP as to the legality of the
securities registered hereunder. Filed herewith.</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top" align="center"><DIV style="margin-left:0px; text-indent:-0px">23.1
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Consent of Independent Registered Public Accounting Firm. Filed herewith</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top" align="center"><DIV style="margin-left:0px; text-indent:-0px">23.2
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Consent of Edwards Angell Palmer &#038; Dodge LLP (contained in Opinion of
Edwards Angell Palmer &#038; Dodge LLP, filed as Exhibit&nbsp;5.1 herewith).</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top" align="center"><DIV style="margin-left:0px; text-indent:-0px">24.1
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Power of Attorney (set forth on the signature page to this Registration
Statement).</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>


<P align="center" style="font-size: 10pt">&nbsp;
</DIV>

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{"company-data": {"conformed-name": "TRIPATH IMAGING INC", "cik": "0001041426", "assigned-sic": "3826", "irs-number": "561995728", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-135498", "film-number": "06936123"}, "business-address": {"street1": "780 PLANTATION DR", "city": "BURLINGTON", "state": "NC", "zip": "27215", "phone": "3362229707"}, "mail-address": {"street1": "PO BOX 1029", "city": "BURLINGTON", "state": "NC", "zip": "27216-1029"}, "former-company": {"former-conformed-name": "AUTOCYTE INC", "date-changed": "19970620"}}
Tripath Imaging Director Plan
As filed with the Securities and Exchange Commission on June 30, 2006
Registration No. 333-
SECURITIES AND EXCHANGE COMMISSION
Washington, D. C. 20549
FORM S-8
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
TRIPATH IMAGING, INC.
(Exact Name of Registrant as Specified in Its Charter)
Delaware
56-1995728
(State or Other Jurisdiction of
(I.R.S. Employer
Incorporation or Organization)
Identification No.)
780 Plantation Drive
Burlington, North Carolina 27215
(Address of Principal Executive Offices)
AMENDED AND RESTATED 1997 DIRECTOR EQUITY PLAN
(formerly entitled 1997 Director Stock Option Plan)
(Full Title of the Plan)
PAUL R. SOHMER, M.D.
PRESIDENT AND CHIEF EXECUTIVE OFFICER
TriPath Imaging, Inc.
780 Plantation Drive
Burlington, North Carolina 27215
(336) 222-9707
(Name, Address and Telephone Number of Agent for Service)
with copies to:
JAMES T. BARRETT, ESQ.
Edwards Angell Palmer & Dodge LLP
111 Huntington Avenue
Boston, Massachusetts 02199
(617) 239-0100
CALCULATION OF REGISTRATION FEE
Proposed Maximum
Proposed Maximum
Title Of Securities
Amount To Be
Offering Price Per
Aggregate Offering
Amount of
To Be Registered
Registered(1)(2)
Share(3)
Price(3)
Registration Fee
Common Stock, $0.01 par value
150,000 shares
$
6.52
$
978,000
$
105
(1)
Pursuant to Rule 416 under the Securities Act of 1933, to the extent additional shares of our
Common Stock may be issued or issuable as a result of a stock split or other distribution
declared at any time by our Board of Directors while this Registration Statement is in effect,
this Registration Statement is hereby deemed to cover all such additional shares of Common
Stock.
(2)
This Registration Statement registers an additional 150,000 shares issuable under our Amended
and Restated 1997 Director Equity Plan (the "Plan"). We have previously registered 450,000
shares issuable under the Plan (Registration Statement No. 333-41467, Registration Statement
No. 333-74936 and Registration Statement No. 333-116274).
(3)
Estimated solely for the purpose of determining the registration fee and computed pursuant to
Rule 457(c) and Rule 457(h)(1) and based upon the average of the high and low sale prices on
June 26, 2006 as reported by the Nasdaq National Market.
Part II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Statement regarding incorporation by reference from effective registration statements:
This Registration Statement registers additional securities of the same class as other
securities for which registration statements filed on Forms S-8 relating to our Amended and
Restated 1997 Director Equity Plan (the "Plan") are already effective. Pursuant to Instruction E
to Form S-8, we incorporate by reference into this Registration Statement the contents of the
registration statements we filed on Forms S-8 (File Nos. 333-41467, 333-74936 and 333-116274) with
the Securities and Exchange Commission on December 4, 1997, December 12, 2001 and June 8, 2004 in
their entirety and including exhibits thereto, relating to the registration of 100,000, 200,000 and
150,000 shares of our Common Stock, $0.01 par value per share, respectively, authorized for
issuance under the Plan. This Registration Statement provides for the registration of an
additional 150,000 shares of Common Stock to be issued under the Plan.
Item 8. Exhibits.
See Exhibit Index immediately following the signature page.
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it
has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and
has duly caused this Registration Statement to be signed on its behalf by the undersigned,
thereunto duly authorized, in the City of Burlington, North Carolina, on this 29th day of June
2006.
TRIPATH IMAGING, INC.
By:
/s/ Paul R. Sohmer, M.D.
Paul R. Sohmer, M.D.
President and Chief Executive Officer
POWER OF ATTORNEY
We, the undersigned officers and directors of TriPath Imaging, Inc., hereby severally
constitute and appoint Paul R. Sohmer, Stephen P. Hall and James T. Barrett, and each of them
singly, our true and lawful attorneys-in-fact, with full power to them in any and all capacities,
to sign any and all amendments to this Registration Statement on Form S-8 including any
post-effective amendments thereto, and to file the same, with exhibits thereto and other documents
in connection therewith, with the Securities and Exchange Commission, hereby ratifying and
confirming all that each of said attorneys-in-fact may do or cause to be done by virtue hereof.
Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has
been signed below by the following persons in the capacities and on the dates indicated:
Signature
Title
Date
/s/ Paul R. Sohmer, M.D.
Paul R. Sohmer, M.D.
President, Chief Executive Officer
and Chairman of the Board
(Principal Executive Officer)
June 29, 2006
/s/ Stephen P. Hall
Stephen P. Hall
Senior Vice-President and Chief
Financial Officer
(Principal Financial Officer and
Principal Accounting Officer)
June 29, 2006
Haywood D. Cochrane, Jr.
Director
June 29, 2006
/s/ Robert E. Curry, Ph.D.
Robert E. Curry, Ph.D.
Director
June 29, 2006
/s/ Richard A. Franco, R. Ph.
Richard A. Franco, R. Ph
Director
June 29, 2006
/s/ Arthur T. King, Ph.D.
Arthur T. King, Ph.D.
Director
June 29, 2006
/s/ Gail F. Lieberman
Gail F. Lieberman
Director
June 29, 2006
EXHIBIT INDEX
Exhibit Number
Description
4.1
Restated Certificate of Incorporation of the Registrant. Filed as
Exhibit 3.1 to the Registrant's Quarterly Report on Form 10-Q for the
quarter ended June 30, 2002 (File No. 0-22885) and incorporated herein
by reference.
4.2
Amended and Restated By-laws of the Registrant. Filed as Exhibit 3.2 to
the Registrant's Quarterly Report on Form 10-Q for the quarter ended
June 30, 2002 (File No. 0-22885) and incorporated herein by reference.
5.1
Opinion of Edwards Angell Palmer & Dodge LLP as to the legality of the
securities registered hereunder. Filed herewith.
23.1
Consent of Independent Registered Public Accounting Firm. Filed herewith
23.2
Consent of Edwards Angell Palmer & Dodge LLP (contained in Opinion of
Edwards Angell Palmer & Dodge LLP, filed as Exhibit 5.1 herewith).
24.1
Power of Attorney (set forth on the signature page to this Registration
Statement).