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<TITLE>KOS PHARMACEUTICALS</TITLE>
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<P align="center"><FONT size="2"><B>SECURITIES AND EXCHANGE COMMISSION<BR>
Washington, D.C. 20549</B></FONT>

<P align="center"><FONT size="2"><B>Form&nbsp;S-8<BR>
REGISTRATION STATEMENT<BR>
UNDER<BR>
THE SECURITIES ACT OF 1933</B></FONT>

<P align="center"><FONT size="2"><B>KOS PHARMACEUTICALS, INC.</B><BR>
<I>(Exact name of registrant as specified in its charter)</I></FONT>

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        <TD width="3%">&nbsp;</TD>
        <TD width="47%">&nbsp;</TD>
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        <TD align="center" valign="top"><FONT size="2"><B>Florida</B><BR>
<I>(State or other jurisdiction of incorporation or organization)</I></FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="center" valign="top"><FONT size="2">
<B>65-0670898</B><BR>
<I>(I.R.S. Employer Identification No.)</I></FONT></TD>
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<P align="center"><FONT size="2"><B>1001 Brickell Bay Drive, 25th Floor<BR>
Miami, Florida 33131<BR>
(305)&nbsp;577-3464</B><BR>
<I>(Address, including zip code, and telephone number, including area code,<BR>
of registrant&#146;s principal executive offices)</I></FONT>

<P align="center"><FONT size="2"><B>KOS PHARMACEUTICALS, INC. 1996 STOCK OPTION PLAN, AS AMENDED</B><BR>
<I>(Full titles of the Plans)</I></FONT>

<P align="center"><FONT size="2">Adrian Adams<BR>
President and Chief Executive Officer<BR>
Kos Pharmaceuticals, Inc.<BR>
1001 Brickell Bay Drive, 25th Floor<BR>
Miami, FL 33131<BR>
(305)&nbsp;577-3464<BR>
<I>(Name, address, including zip code, and telephone number,<BR>
including area code, of agent for service)</I></FONT>

<P align="center"><FONT size="2">Copies of all communications to:</FONT>

<P align="center"><FONT size="2">Steven Sonberg, Esq.<BR>
Holland &#038; Knight LLP<BR>
701 Brickell Avenue<BR>
Suite&nbsp;3000<BR>
Miami, FL 33131<BR>
(305)&nbsp;374-8500<BR>
<I>(Name, address, including zip code, and telephone number,<BR>
including area code, of agent for service)</I></FONT>

<P align="center"><FONT size="2"><B>CALCULATION OF REGISTRATION FEE</B></FONT>

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<TABLE cellspacing="0" border="0" cellpadding="0" width="75%">
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        <TD width="5%">&nbsp;</TD>
        <TD width="6%">&nbsp;</TD>
        <TD width="1%">&nbsp;</TD>
        <TD width="7%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="4%">&nbsp;</TD>
        <TD width="1%">&nbsp;</TD>
        <TD width="4%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="8%">&nbsp;</TD>
        <TD width="1%">&nbsp;</TD>
        <TD width="9%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="6%">&nbsp;</TD>
        <TD width="1%">&nbsp;</TD>
        <TD width="7%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><FONT size="1"><B>Title of Securities</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1"><B>Proposed Maximum</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1"><B>Proposed Maximum</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><FONT size="1"><B>to be</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1"><B>Amount to</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1"><B>Offering Price Per</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1"><B>Aggregate Offering</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1"><B>Amount of</B></FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><FONT size="1"><B>Registered</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1"><B>be Registered(1)</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1"><B>Share(2)</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1"><B>Price(2)</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1"><B>Registration Fee(3)</B></FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><HR size="1" noshade></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD colspan="3"><HR size="1" noshade></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD colspan="3"><HR size="1" noshade></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD colspan="3"><HR size="1" noshade></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD colspan="3"><HR size="1" noshade></TD>
</TR>
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        <TD><DIV style="margin-left:10px; text-indent:-10px"><FONT size="2">Common Stock,
$.01 par value</FONT></DIV></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="right"><FONT size="2">5,000,000</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="right"><FONT size="2">$</FONT></TD>
        <TD align="right"><FONT size="2">17.6795</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="right"><FONT size="2">$</FONT></TD>
        <TD align="right"><FONT size="2">88,397,500</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="right"><FONT size="2">$</FONT></TD>
        <TD align="right"><FONT size="2">8,132.57</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR>
        <TD><DIV style="margin-left:10px; text-indent:-10px"><FONT size="2">&nbsp;</FONT></DIV></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><HR size="4" noshade></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
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        <TD><FONT size="2">&nbsp;</FONT></TD>
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        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><HR size="4" noshade></TD>
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        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
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<P>
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<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR valign="top">
      <TD width="1%" align="left" nowrap><FONT size="2">(1)</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="96%"><FONT size="2">Represents additional shares of Kos Pharmaceuticals, Inc. Common
Stock, par value $.01 per share (the &#147;Common Stock&#148;), to be issued
pursuant to the Kos Pharmaceuticals, Inc. 1996 Stock Option Plan, as
amended.</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="top">
      <TD width="1%" align="left" nowrap><FONT size="2">(2)</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="96%"><FONT size="2">Estimated solely for the purpose of calculating the registration
fee pursuant to Rule&nbsp;457(h) of the Securities Act of 1933, as
amended, and based on the average of the high and low prices reported
on the Nasdaq National Market on June&nbsp;11, 2002.</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="top">
      <TD width="1%" align="left" nowrap><FONT size="2">(3)</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="96%"><FONT size="2">Registration fees were previously paid for the Kos
Pharmaceuticals, Inc. 1996 Stock Option Plan (the &#147;Plan&#148;) filed on a
Form&nbsp;S-8 registration statement (4,000,000 shares; Registration No.
333-35533) and for an amendment to the Plan filed on a Form&nbsp;S-8
Registration Statement (3,000,000 shares Registration No.&nbsp;333-59396).
The Plan has been further amended to increase the number of covered
shares from 7,000,000 to 12,000,000. The fee being paid with this
Registration Statement pertains to the 5,000,000 additional shares.</FONT></TD>
</TR>
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<P align="center"><FONT size="2"><B>EXPLANATORY NOTE</B></FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;As permitted by General Instruction E of Form&nbsp;S-8, Kos Pharmaceuticals,
Inc. (the &#147;Company&#148;) hereby incorporates by reference the information contained
in the earlier registration statements on Form&nbsp;S-8 (Registration No.&nbsp;333-35533)
and (Registration No.&nbsp;333-59396) relating to the Kos Pharmaceuticals, Inc. 1996
Stock Option Plan (the &#147;Plan&#148;), filed with the Securities and Exchange
Commission on September&nbsp;12, 1997 and April&nbsp;23, 2001, respectively, in
connection with an increase from 7,000,000 to 12,000,000 in the number of
shares of the Company&#146;s Common Stock that may be issued under the Plan.
</FONT>
<P align="center"><FONT size="2"><B>PART II</B></FONT>

<P align="center"><FONT size="2"><B>INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</B></FONT>

<P align="left"><FONT size="2"><B>Item&nbsp;8. Exhibits</B>.</FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The exhibits filed as part of this Registration Statement are as follows:
</FONT>
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        <TD width="8%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="3%">&nbsp;</TD>
        <TD width="8%">&nbsp;</TD>
        <TD width="76%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><FONT size="1"><B>Exhibit Number</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="left"><FONT size="1"><B>Description</B></FONT></TD>
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        <TD nowrap align="center"><HR size="1" noshade></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
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        <TD nowrap align="center"><HR size="1" noshade></TD>
</TR>
<TR><TD>&nbsp;</TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">5</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
&#151;
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">Opinion of Holland &#038; Knight LLP</FONT></TD>
</TR>
<TR><TD>&nbsp;</TD></TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">23.1</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
&#151;
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">Consent of Holland &#038; Knight LLP (included in Exhibit&nbsp;5)</FONT></TD>
</TR>
<TR><TD>&nbsp;</TD></TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">24</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
&#151;
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">Powers of Attorney (included on the signature page to this
Registration Statement)</FONT></TD>
</TR>
</TABLE>
</CENTER>
<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;As permitted by Rule&nbsp;437a of the Securities Act of 1933 (the &#147;Securities
Act&#148;), the Company has not filed the written consent of Arthur Andersen LLP as
required by Section&nbsp;7 of the Securities Act. The Company has made reasonable
efforts to obtain a written consent from Arthur Andersen LLP in connection with
this Registration Statement, but such efforts have been unsuccessful. As a
result of the foregoing, investors may be unable to recover against Arthur
Andersen LLP under Section&nbsp;11 of the Securities Act for any untrue statements
of material fact contained in the financial statements audited by Arthur
Andersen LLP for the fiscal year ended December&nbsp;31, 2001 or any omissions to
state a material fact required to be stated therein, which financial statements
are incorporated in this Registration Statement.
</FONT>
<P align="center"><FONT size="2">2</FONT>
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<P align="center"><FONT size="2"><B>SIGNATURES</B></FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act of 1933, the
registrant, Kos Pharmaceuticals, Inc., certifies that it has reasonable grounds
to believe that it meets all of the requirements for filing on Form&nbsp;S-8 and has
duly caused this Registration Statement to be signed on its behalf by the
undersigned, thereunto duly authorized, in the city of Miami, State of Florida,
on the 4th day of June, 2002.
</FONT>
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        <TD width="45%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="50%">&nbsp;</TD>
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        <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
<B>KOS PHARMACEUTICALS, INC</B></FONT></TD>
</TR>
<TR><TD>&nbsp;</TD></TR>
<TR><TD>&nbsp;</TD></TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
By: /s/ Adrian Adams</FONT></TD>
</TR>
<TR>
        <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
<HR size="1" noshade></FONT></TD>
</TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Adrian Adams, President and
Chief Executive Officer</FONT></TD>
</TR>
</TABLE>
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<P align="center"><FONT size="2"><B>POWER OF ATTORNEY</B></FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears below
constitutes and appoints Adrian Adams and Juan F. Rodriguez and each of them,
his true and lawful attorney-in-fact and agents, with full power of
substitution and resubstitution for him and in his name, place and stead, in
any and all capacities, to sign any and all amendments (including
post-effective amendments) to this Registration Statement and to file the same,
with all exhibits thereto, and other documents in connection therewith, with
the Securities and Exchange Commission, granting unto said attorneys-in-fact
and agents full power and authority to do and perform each and every act and
thing requisite and necessary to be done in and about the premises, as fully to
all intents and purposes as he might or could do in person, hereby ratifying
and confirming all that each of said attorneys-in-fact or his substitute or
substitutes, may lawfully do or cause to be done by virtue hereof.
</FONT>
<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed below by the following persons on the
dates indicated.
</FONT>
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<TR valign="bottom">
        <TD width="38%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="41%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="11%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><FONT size="1"><B>Signature</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center"><FONT size="1"><B>Title</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center"><FONT size="1"><B>Date</B></FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><HR size="1" noshade></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center"><HR size="1" noshade></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center"><HR size="1" noshade></TD>
</TR>
<TR><TD>&nbsp;</TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ Michael Jaharis
<HR size="1" noshade>
Michael Jaharis</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Chairman Emeritus of the Board of
Directors
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">June&nbsp;4, 2002</FONT></TD>
</TR>
<TR><TD>&nbsp;</TD></TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ Daniel M. Bell
<HR size="1" noshade>
Daniel M. Bell</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Chairman of the Board of Directors
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">June&nbsp;4, 2002</FONT></TD>
</TR>
<TR><TD>&nbsp;</TD></TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ Robert E. Baldini
<HR size="1" noshade>
Robert E. Baldini</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Vice Chairman of the Board
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">June&nbsp;4, 2002</FONT></TD>
</TR>
<TR><TD>&nbsp;</TD></TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ Adrian Adams
<HR size="1" noshade>
Adrian Adams</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
President, Chief Executive
Officer, and Director<BR>
(Principal Executive Officer)
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">June&nbsp;4, 2002</FONT></TD>
</TR>
<TR><TD>&nbsp;</TD></TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ Christopher P. Kiritsy
<HR size="1" noshade>
Christopher P. Kiritsy</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Senior Vice President, Chief<BR>
Financial Officer<BR>
(Principal Financial Officer)
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">June&nbsp;4, 2002</FONT></TD>
</TR>
<TR><TD>&nbsp;</TD></TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ Juan F. Rodriguez
<HR size="1" noshade>
Juan F. Rodriguez</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Vice President, Controller<BR>
(Principal Accounting Officer)
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">June&nbsp;4, 2002</FONT></TD>
</TR>
<TR><TD>&nbsp;</TD></TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ John Brademas
<HR size="1" noshade>
John Brademas</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Director
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">June&nbsp;4, 2002</FONT></TD>
</TR>
<TR><TD>&nbsp;</TD></TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ Steve Jaharis
<HR size="1" noshade>
Steven Jaharis</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Director
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">June&nbsp;4, 2002</FONT></TD>
</TR>
<TR><TD>&nbsp;</TD></TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ Louis C. Lasagna
<HR size="1" noshade>
Louis C. Lasagna</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Director
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">June&nbsp;4, 2002</FONT></TD>
</TR>

</TR>
<TR><TD>&nbsp;</TD></TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ Nicolaos E. Madias
<HR size="1" noshade>
Nicolaos E. Madias</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Director
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">June&nbsp;10, 2002</FONT></TD>
</TR>

<TR><TD>&nbsp;</TD></TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ Mark Novitch
<HR size="1" noshade>
Mark Novitch</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Director
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">June&nbsp;4, 2002</FONT></TD>
</TR>
<TR><TD>&nbsp;</TD></TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ Frederick B. Whittemore
<HR size="1" noshade>
Frederick B. Whittemore</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Director
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">June&nbsp;4, 2002</FONT></TD>
</TR>
</TABLE>
</CENTER>
<P align="center"><FONT size="2">3</FONT>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>
<P align="center"><FONT size="2"><B>EXHIBIT INDEX</B></FONT>

<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="85%">
<TR valign="bottom">
        <TD width="6%">&nbsp;</TD>
        <TD width="3%">&nbsp;</TD>
        <TD width="3%">&nbsp;</TD>
        <TD width="6%">&nbsp;</TD>
        <TD width="82%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><FONT size="1"><B>Exhibit Number</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center"><FONT size="1"><B>Description</B></FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><HR size="1" noshade></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center"><HR size="1" noshade></TD>
</TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">5</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
&#151;
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">Opinion of Holland &#038; Knight LLP</FONT></TD>
</TR>
<TR><TD>&nbsp;</TD></TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">23.1</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
&#151;
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">Consent of Holland &#038; Knight LLP (included in Exhibit&nbsp;5)</FONT></TD>
</TR>
<TR><TD>&nbsp;</TD></TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">24</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
&#151;
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">Powers of Attorney (included on the signature page to this Registration Statement)</FONT></TD>
</TR>
</TABLE>
</CENTER>





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{"company-data": {"conformed-name": "KOS PHARMACEUTICALS INC", "cik": "0001018952", "assigned-sic": "2834", "irs-number": "650670898", "state-of-incorporation": "FL", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-90382", "film-number": "02677872"}, "business-address": {"street1": "1001 BRICKELL BAY DR STE 25", "city": "MIAMI", "state": "FL", "zip": "33131", "phone": "3055773464"}}
KOS PHARMACEUTICALS
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
Form S-8
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
KOS PHARMACEUTICALS, INC.
(Exact name of registrant as specified in its charter)
Florida
(State or other jurisdiction of incorporation or organization)
65-0670898
(I.R.S. Employer Identification No.)
1001 Brickell Bay Drive, 25th Floor
Miami, Florida 33131
(305) 577-3464
(Address, including zip code, and telephone number, including area code,
of registrant's principal executive offices)
KOS PHARMACEUTICALS, INC. 1996 STOCK OPTION PLAN, AS AMENDED
(Full titles of the Plans)
Adrian Adams
President and Chief Executive Officer
Kos Pharmaceuticals, Inc.
1001 Brickell Bay Drive, 25th Floor
Miami, FL 33131
(305) 577-3464
(Name, address, including zip code, and telephone number,
including area code, of agent for service)
Copies of all communications to:
Steven Sonberg, Esq.
Holland & Knight LLP
701 Brickell Avenue
Suite 3000
Miami, FL 33131
(305) 374-8500
(Name, address, including zip code, and telephone number,
including area code, of agent for service)
CALCULATION OF REGISTRATION FEE
Title of Securities
Proposed Maximum
Proposed Maximum
to be
Amount to
Offering Price Per
Aggregate Offering
Amount of
Registered
be Registered(1)
Share(2)
Price(2)
Registration Fee(3)
Common Stock,
$.01 par value
5,000,000
$
17.6795
$
88,397,500
$
8,132.57
(1)
Represents additional shares of Kos Pharmaceuticals, Inc. Common
Stock, par value $.01 per share (the "Common Stock"), to be issued
pursuant to the Kos Pharmaceuticals, Inc. 1996 Stock Option Plan, as
amended.
(2)
Estimated solely for the purpose of calculating the registration
fee pursuant to Rule 457(h) of the Securities Act of 1933, as
amended, and based on the average of the high and low prices reported
on the Nasdaq National Market on June 11, 2002.
(3)
Registration fees were previously paid for the Kos
Pharmaceuticals, Inc. 1996 Stock Option Plan (the "Plan") filed on a
Form S-8 registration statement (4,000,000 shares; Registration No.
333-35533) and for an amendment to the Plan filed on a Form S-8
Registration Statement (3,000,000 shares Registration No. 333-59396).
The Plan has been further amended to increase the number of covered
shares from 7,000,000 to 12,000,000. The fee being paid with this
Registration Statement pertains to the 5,000,000 additional shares.
EXPLANATORY NOTE
As permitted by General Instruction E of Form S-8, Kos Pharmaceuticals,
Inc. (the "Company") hereby incorporates by reference the information contained
in the earlier registration statements on Form S-8 (Registration No. 333-35533)
and (Registration No. 333-59396) relating to the Kos Pharmaceuticals, Inc. 1996
Stock Option Plan (the "Plan"), filed with the Securities and Exchange
Commission on September 12, 1997 and April 23, 2001, respectively, in
connection with an increase from 7,000,000 to 12,000,000 in the number of
shares of the Company's Common Stock that may be issued under the Plan.
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 8. Exhibits
.
The exhibits filed as part of this Registration Statement are as follows:
Exhibit Number
Description
5
—
Opinion of Holland & Knight LLP
23.1
—
Consent of Holland & Knight LLP (included in Exhibit 5)
24
—
Powers of Attorney (included on the signature page to this
Registration Statement)
As permitted by Rule 437a of the Securities Act of 1933 (the "Securities
Act"), the Company has not filed the written consent of Arthur Andersen LLP as
required by Section 7 of the Securities Act. The Company has made reasonable
efforts to obtain a written consent from Arthur Andersen LLP in connection with
this Registration Statement, but such efforts have been unsuccessful. As a
result of the foregoing, investors may be unable to recover against Arthur
Andersen LLP under Section 11 of the Securities Act for any untrue statements
of material fact contained in the financial statements audited by Arthur
Andersen LLP for the fiscal year ended December 31, 2001 or any omissions to
state a material fact required to be stated therein, which financial statements
are incorporated in this Registration Statement.
2
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, the
registrant, Kos Pharmaceuticals, Inc., certifies that it has reasonable grounds
to believe that it meets all of the requirements for filing on Form S-8 and has
duly caused this Registration Statement to be signed on its behalf by the
undersigned, thereunto duly authorized, in the city of Miami, State of Florida,
on the 4th day of June, 2002.
KOS PHARMACEUTICALS, INC
By: /s/ Adrian Adams
Adrian Adams, President and
Chief Executive Officer
POWER OF ATTORNEY
KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears below
constitutes and appoints Adrian Adams and Juan F. Rodriguez and each of them,
his true and lawful attorney-in-fact and agents, with full power of
substitution and resubstitution for him and in his name, place and stead, in
any and all capacities, to sign any and all amendments (including
post-effective amendments) to this Registration Statement and to file the same,
with all exhibits thereto, and other documents in connection therewith, with
the Securities and Exchange Commission, granting unto said attorneys-in-fact
and agents full power and authority to do and perform each and every act and
thing requisite and necessary to be done in and about the premises, as fully to
all intents and purposes as he might or could do in person, hereby ratifying
and confirming all that each of said attorneys-in-fact or his substitute or
substitutes, may lawfully do or cause to be done by virtue hereof.
Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed below by the following persons on the
dates indicated.
Signature
Title
Date
/s/ Michael Jaharis
Michael Jaharis
Chairman Emeritus of the Board of
Directors
June 4, 2002
/s/ Daniel M. Bell
Daniel M. Bell
Chairman of the Board of Directors
June 4, 2002
/s/ Robert E. Baldini
Robert E. Baldini
Vice Chairman of the Board
June 4, 2002
/s/ Adrian Adams
Adrian Adams
President, Chief Executive
Officer, and Director
(Principal Executive Officer)
June 4, 2002
/s/ Christopher P. Kiritsy
Christopher P. Kiritsy
Senior Vice President, Chief
Financial Officer
(Principal Financial Officer)
June 4, 2002
/s/ Juan F. Rodriguez
Juan F. Rodriguez
Vice President, Controller
(Principal Accounting Officer)
June 4, 2002
/s/ John Brademas
John Brademas
Director
June 4, 2002
/s/ Steve Jaharis
Steven Jaharis
Director
June 4, 2002
/s/ Louis C. Lasagna
Louis C. Lasagna
Director
June 4, 2002
/s/ Nicolaos E. Madias
Nicolaos E. Madias
Director
June 10, 2002
/s/ Mark Novitch
Mark Novitch
Director
June 4, 2002
/s/ Frederick B. Whittemore
Frederick B. Whittemore
Director
June 4, 2002
3
EXHIBIT INDEX
Exhibit Number
Description
5
—
Opinion of Holland & Knight LLP
23.1
—
Consent of Holland & Knight LLP (included in Exhibit 5)
24
—
Powers of Attorney (included on the signature page to this Registration Statement)