<PAGE>

      As filed with the Securities and Exchange Commission on June 2, 2006

                                                     Registration No. 333-______
================================================================================

                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                          -----------------------------

                                    FORM S-8
                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933

                          -----------------------------

                                LITTELFUSE, INC.
               (Exact name of issuer as specified in its charter)

                Delaware                                         36-3795742
     (State or other jurisdiction of                          (I.R.S. Employer
     incorporation or organization)                          Identification No.)

       800 East Northwest Highway
          Des Plaines, Illinois                                     60016
(Address of principal executive offices)                         (Zip Code)

                             LITTELFUSE, INC. EQUITY
                           INCENTIVE COMPENSATION PLAN
                            (Full title of the plan)

        Gordon Hunter                               Copies of Communications to:
    Chairman, President                                  William C. Hermann
 and Chief Executive Officer                           Chapman and Cutler LLP
      Littelfuse, Inc.                                 111 West Monroe Street
 800 East Northwest Highway                           Chicago, Illinois  60603
Des Plaines, Illinois  60016                               (312) 845-3000
       (847) 824-1188
(Name, address and telephone
number of agent for service)

                            -------------------------

                         CALCULATION OF REGISTRATION FEE

<TABLE>
<CAPTION>
============================================================================================
                                               Proposed          Proposed
 Title of                                       maximum           maximum
securities                Amount               offering          aggregate        Amount of
   to be                   to be                price            offering       registration
registered           registered(1)(2)        per share(3)          price            fee
----------           ----------------        ------------        ---------      ------------
<S>                  <C>                     <C>                 <C>            <C>
Common Stock,
$.01 par value       1,250,000 Shares           $34.67          $43,337,500       $4,637.11

============================================================================================
</TABLE>

(1) Pursuant to Rule 416, this Registration Statement also covers an
indeterminate number of shares as may be issued as a result of the anti-dilution
provisions of the Plan.

(2) In addition, pursuant to Rule 416(c) under the Securities Act of 1933, as
amended (the "Securities Act"), to the extent applicable, this registration
statement also covers an indeterminate amount of interests to be offered or sold
pursuant to the employee benefit plan described herein.

(3) Pursuant to Rule 457(c) and (h), the proposed maximum offering price per
share and maximum aggregate offering price and amount of registration fee are
calculated based upon a price per share of $34.67, the average of the high and
low price for the shares of Littelfuse, Inc. Common Stock as reported by the
Nasdaq Stock Market National Market System on May 30, 2006, a date within five
business days prior to the date of filing the Registration Statement.

================================================================================

<PAGE>

                                     PART I

                       INFORMATION REQUIRED IN PROSPECTUS.

ITEM 1.  PLAN INFORMATION.

         The documents containing the information specified in this Item 1 will
be sent or given to employees, officers or others as specified by Rule
428(b)(1). In accordance with the rules and regulations of the Securities and
Exchange Commission (the "Commission") and the instructions to Form S-8, such
documents are not being filed with the Commission either as part of this
Registration Statement or as prospectuses or prospectus supplements pursuant to
Rule 424.

ITEM 2.  REGISTRATION INFORMATION AND EMPLOYEE PLAN ANNUAL INFORMATION.

         The documents containing the information specified in this Item 2 will
be sent or given to employees, officers, directors or others as specified by
Rule 428(b)(1). In accordance with the rules and regulations of the Commission
and the instructions to Form S-8, such documents are not being filed with the
Commission either as part of this Registration Statement or as prospectuses or
prospectus supplements pursuant to Rule 424. Such documents, together with the
documents incorporated by reference herein pursuant to Item 3 of Part II of this
Registration Statement on Form S-8, constitute a prospectus that meets the
requirements of Section 10(a) of the Securities Act, and are available, free of
charge, upon written or oral request as follows: Littelfuse, Inc., 800 East
Northwest Highway, Des Plaines, Illinois 60016, attention Secretary; Tel. No.:
(847) 824-1188.


                                     PART II

               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

ITEM 3.  INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

         The following documents which have been filed with the Commission by
the Company pursuant to the Securities Exchange Act of 1934 ("1934 Act") are
incorporated herein by reference:

                  (a) The Company's Annual Report on Form 10-K for the fiscal
         year ended December 31, 2005 (1934 Act File No. 0-20388).

                  (b) The Company's Quarterly Report on Form 10-Q for the fiscal
         quarter ended April 1, 2006 (1934 Act File No. 0-20388).

                  (c) The Company's Current Reports on Form 8-K filed on
         February 7, 2006, February 8, 2006, February 10, 2006, February 23,
         2006, March 1, 2006, March 6, 2006,


                                      II-1
<PAGE>

         March 7, 2006, March 10, 2006, March 20, 2006, May 5, 2006 (including
         as amended), May 9, 2006 and May 11, 2006 (excluding any portions of
         such reports that were furnished).

                  (d) The description of the Company's Common Stock which is
         contained in the Form 10: General Form for Registration of Securities
         pursuant to Section 12(b) or (g) of the 1934 Act filed with the
         Commission on July 7, 1992 (1934 Act File No. 0-20388).

         All documents subsequently filed by the Company pursuant to Sections
13(a), 13(c), 14 and 15(d) of the 1934 Act (excluding any portions of such
documents that were furnished), prior to the filing of a post-effective
amendment which indicates that all securities offered hereby have been sold or
which deregisters all such securities then remaining unsold, shall be deemed to
be incorporated by reference into this Registration Statement and to be a part
hereof from the date of filing such documents. Any statement contained in an
incorporated document shall be deemed to be modified or superseded to the extent
that a statement contained herein or in any subsequently filed incorporated
document modifies or supersedes such statement.

ITEM 4.  DESCRIPTION OF SECURITIES.

         Not applicable.

ITEM 5.  INTERESTS OF NAMED EXPERTS AND COUNSEL.

         The consolidated financial statements of Littelfuse, Inc. incorporated
by reference in Littelfuse, Inc.'s Annual Report (Form 10-K) for the year ended
December 31, 2005 (including the schedule appearing therein), and Littelfuse,
Inc. management's assessment of the effectiveness of internal control over
financial reporting as of December 31, 2005 included therein, have been audited
by Ernst & Young LLP, independent registered public accounting firm, as set
forth in their reports thereon, incorporated by reference therein, and
incorporated herein by reference. Such consolidated financial statements and
management's assessment are incorporated herein by reference in reliance upon
such reports given on the authority of such firm as experts in accounting and
auditing.

ITEM 6.  INDEMNIFICATION OF DIRECTORS AND OFFICERS

         Section 145 of the Delaware General Corporation Law ("DGCL") gives
Delaware corporations the power to indemnify present and former officers and
directors under certain circumstances. The Certificate of Incorporation of the
Company provides for indemnification by the Company to the fullest extent
permitted by Section 145 of the DGCL of certain persons (including officers and
directors) in connection with any threatened, pending or completed action, suit
or proceeding brought or threatened against such person by reason of his
position with the Company or service at the request of the Company. The
Certificate of Incorporation further provides that indemnification shall not be
exclusive of any rights to which those indemnified may be entitled under any
bylaw, agreement, vote of stockholders or disinterested directors or otherwise.

         In addition, the Company maintains a directors' and officers' liability
insurance policy to insure its liability under the above-described provision of
its Certificate of Incorporation and to insure its individual directors and
officers certain obligations not covered by such provisions.


                                      II-2
<PAGE>

ITEM 8.  EXHIBITS

         The following exhibits are submitted herewith or incorporated by
reference herein.

EXHIBIT
NUMBER                                DESCRIPTION
-------                               -----------

  4.1       Littelfuse, Inc. Equity Incentive Compensation Plan (filed as
            Exhibit A to the Company's Proxy Statement for Annual Meeting of
            Stockholders to be held on May 5, 2006 (1934 Act File No. 0-20388),
            and incorporated herein by reference)

  4.2       Certificate of Incorporation of Littelfuse, Inc. (filed as Exhibit
            3.1 to the Company's Form 10-K for the fiscal year ended January 3,
            1998 (1934 Act File No. 0-20388), and incorporated herein by
            reference)

  4.3       Bylaws of Littelfuse, Inc. (filed as Exhibit 3(II) to the Company's
            Form 8-K/A dated May 5, 2006 (1934 Act File No. 0-20388), and
            incorporated herein by reference)

  5.1       Opinion of Chapman and Cutler LLP

 23.1       Consent of Chapman and Cutler LLP (included in Exhibit 5.1)

 23.2       Consent of Ernst & Young LLP

 24.1       Power of Attorney (set forth on page II-7 of this Registration
            Statement)


                                      II-3

<PAGE>


ITEM 9.  UNDERTAKINGS

(a)      The undersigned registrant hereby undertakes:

         (1)      To file, during any period in which offers or sales are being
                  made, a post-effective amendment to this registration
                  statement

                  (i)      To include any prospectus required by Section
                           10(a)(3) of the Securities Act of 1933;

                  (ii)     To reflect in the prospectus any facts or events
                           arising after the effective date of the registration
                           statement (or the most recent post-effective
                           amendment thereof) which, individually or in the
                           aggregate, represent a fundamental change in the
                           information set forth in the registration statement.
                           Notwithstanding the foregoing, any increase or
                           decrease in volume of securities offered (if the
                           total dollar value of securities offered would not
                           exceed that which was registered) and any deviation
                           from the low or high end of the estimated maximum
                           offering range may be reflected in the form of
                           prospectus filed with the Commission pursuant to Rule
                           424(b) if, in the aggregate, the changes in volume
                           and price represent no more than a 20 percent change
                           in the maximum aggregate offering price set forth in
                           the "Calculation of Registration Fee" table in the
                           effective registration statement;

                  (iii)    To include any material information with respect to
                           the plan of distribution not previously disclosed in
                           the registration statement or any material change to
                           such information in the registration statement;

                  provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii) do
                  not apply if the information required to be included in a
                  post-effective amendment by those paragraphs is contained in
                  reports filed with or furnished to the Commission by the
                  registrant pursuant to Section 13 or Section 15(d) of the
                  Securities Exchange Act of 1934 that are incorporated by
                  reference in the registration statement.

         (2)      That, for the purpose of determining any liability under the
                  Securities Act of 1933, each such post-effective amendment
                  shall be deemed to be a new registration statement relating to
                  the securities offered therein, and the offering of such
                  securities at that time shall be deemed to be the initial bona
                  fide offering thereof.

         (3)      To remove from registration by means of a post-effective
                  amendment any of the securities being registered which remain
                  unsold at the termination of the offering.

(b)      The undersigned registrant hereby undertakes that, for purposes of
         determining any liability under the Securities Act of 1933, each filing
         of the registrant's annual report pursuant to Section 13(a) or Section
         15(d) of the Securities Exchange Act


                                      II-4
<PAGE>

         of 1934 (and, where applicable, each filing of an employee benefit
         plan's annual report pursuant to Section 15(d) of the Securities
         Exchange Act of 1934) that is incorporated by reference in the
         Registration Statement shall be deemed to be a new registration
         statement relating to the securities offered therein, and the offering
         of such securities at that time shall be deemed to be the initial bona
         fide offering thereof.

(c)      Insofar as indemnification for liabilities arising under the Securities
         Act of 1933 may be permitted to directors, officers and controlling
         persons of the registrant pursuant to the provisions described under
         Item 6 above, or otherwise, the registrant has been advised that in the
         opinion of the Commission such indemnification is against public policy
         as expressed in the Securities Act of 1933 and is, therefore,
         unenforceable. In the event that a claim for indemnification against
         such liabilities (other than the payment by the registrant of expenses
         incurred or paid by a director, officer or controlling person of the
         registrant in the successful defense of any action, suit or proceeding)
         is asserted by such director, officer or controlling person in
         connection with the securities being registered, the registrant will,
         unless in the opinion of its counsel the matter has been settled by
         controlling precedent, submit to a court of appropriate jurisdiction
         the question whether such indemnification by it is against public
         policy as expressed in the Securities Act of 1933 and will be governed
         by the final adjudication of such issue.


                                      II-5
<PAGE>


                                   SIGNATURES

         Pursuant to the requirements of the Securities Act of 1933, the
registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of Des Plaines, State of Illinois, on June 2, 2006.


                                        LITTELFUSE, INC.


                                        By:         /s/ Gordon Hunter
                                           -------------------------------------
                                                      Gordon Hunter,
                                                    Chairman, President
                                                and Chief Executive Officer



                                      II-6

<PAGE>




                                POWER OF ATTORNEY

         Each person whose signature appears below hereby constitutes and
appoints Gordon Hunter and Philip G. Franklin and each of them, his true and
lawful attorneys-in-fact and agents, with full power and substitution and
resubstitution for him or her in his or her name, place and stead, in any and
all capacities to sign any and all pre-effective and/or post-effective
amendments to this Registration Statement and to file the same, with all
exhibits thereto, and other documents in connection therewith with the
Securities and Exchange Commission under the Securities Act of 1933.

         Pursuant to the requirements of the Securities Act of 1933, this
registration statement has been signed by the following persons in the
capacities indicated on May 22, 2006.

           SIGNATURE                                        TITLE
           ---------                                        -----

     /s/ Gordon Hunter                              Chairman, President
------------------------------                   and Chief Executive Officer
         Gordon Hunter                          (Principal executive officer)

   /s/ Philip G. Franklin                     Vice President, Operations Support
------------------------------                    and Chief Financial Officer
       Philip G. Franklin                          (Principal financial and
                                                     accounting officer)

    /s/ John P. Driscoll                                   Director
------------------------------
        John P. Driscoll

    /s/ Anthony Grillo                                     Director
------------------------------
        Anthony Grillo

    /s/ Bruce A. Karsh                                     Director
------------------------------
        Bruce A. Karsh

    /s/ John E. Major                                      Director
------------------------------
        John E. Major

   /s/ Ronald L. Schubel                                   Director
------------------------------
       Ronald L. Schubel


                                      II-7
<PAGE>

EXHIBIT
NUMBER                                DESCRIPTION
-------                               -----------

  4.1       Littelfuse, Inc. Equity Incentive Compensation Plan (filed as
            Exhibit A to the Company's Proxy Statement for Annual Meeting of
            Stockholders to be held on May 5, 2006 (1934 Act File No. 0-20388),
            and incorporated herein by reference)

  4.2       Certificate of Incorporation of Littelfuse, Inc. (filed as Exhibit
            3.1 to the Company's Form 10-K for the fiscal year ended January 3,
            1998 (1934 Act File No. 0-20388), and incorporated herein by
            reference)

  4.3       Bylaws of Littelfuse, Inc. (filed as Exhibit 3(II) to the Company's
            Form 8-K/A dated May 5, 2006 (1934 Act File No. 0-20388), and
            incorporated herein by reference)

  5.1       Opinion of Chapman and Cutler LLP

 23.1       Consent of Chapman and Cutler LLP (included in Exhibit 5.1)

 23.2       Consent of Ernst & Young LLP

 24.1       Power of Attorney (set forth on page II-7 of this Registration
            Statement)


                                       E-1
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{"company-data": {"conformed-name": "LITTELFUSE INC /DE", "cik": "0000889331", "assigned-sic": "3613", "irs-number": "363795742", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-134700", "film-number": "06883563"}, "business-address": {"street1": "800 E NORTHWEST HWY", "city": "DES PLAINES", "state": "IL", "zip": "60016", "phone": "7088241188"}, "mail-address": {"street1": "800 E. NORTHWEST HWY", "city": "DES PLAINES", "state": "IL", "zip": "60016"}}
As filed with the Securities and Exchange Commission on June 2, 2006

                                                     Registration No. 333-______
================================================================================

                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                          -----------------------------

                                    FORM S-8
                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933

                          -----------------------------

                                LITTELFUSE, INC.
               (Exact name of issuer as specified in its charter)

                Delaware                                         36-3795742
     (State or other jurisdiction of                          (I.R.S. Employer
     incorporation or organization)                          Identification No.)

       800 East Northwest Highway
          Des Plaines, Illinois                                     60016
(Address of principal executive offices)                         (Zip Code)

                             LITTELFUSE, INC. EQUITY
                           INCENTIVE COMPENSATION PLAN
                            (Full title of the plan)

        Gordon Hunter                               Copies of Communications to:
    Chairman, President                                  William C. Hermann
 and Chief Executive Officer                           Chapman and Cutler LLP
      Littelfuse, Inc.                                 111 West Monroe Street
 800 East Northwest Highway                           Chicago, Illinois  60603
Des Plaines, Illinois  60016                               (312) 845-3000
       (847) 824-1188
(Name, address and telephone
number of agent for service)

                            -------------------------

                         CALCULATION OF REGISTRATION FEE
============================================================================================
                                               Proposed          Proposed
 Title of                                       maximum           maximum
securities                Amount               offering          aggregate        Amount of
   to be                   to be                price            offering       registration
registered           registered(1)(2)        per share(3)          price            fee
----------           ----------------        ------------        ---------      ------------
Common Stock,
$.01 par value       1,250,000 Shares           $34.67          $43,337,500       $4,637.11

============================================================================================
(1) Pursuant to Rule 416, this Registration Statement also covers an
indeterminate number of shares as may be issued as a result of the anti-dilution
provisions of the Plan.

(2) In addition, pursuant to Rule 416(c) under the Securities Act of 1933, as
amended (the "Securities Act"), to the extent applicable, this registration
statement also covers an indeterminate amount of interests to be offered or sold
pursuant to the employee benefit plan described herein.

(3) Pursuant to Rule 457(c) and (h), the proposed maximum offering price per
share and maximum aggregate offering price and amount of registration fee are
calculated based upon a price per share of $34.67, the average of the high and
low price for the shares of Littelfuse, Inc. Common Stock as reported by the
Nasdaq Stock Market National Market System on May 30, 2006, a date within five
business days prior to the date of filing the Registration Statement.

================================================================================
PART I

                       INFORMATION REQUIRED IN PROSPECTUS.

ITEM 1.  PLAN INFORMATION.

         The documents containing the information specified in this Item 1 will
be sent or given to employees, officers or others as specified by Rule
428(b)(1). In accordance with the rules and regulations of the Securities and
Exchange Commission (the "Commission") and the instructions to Form S-8, such
documents are not being filed with the Commission either as part of this
Registration Statement or as prospectuses or prospectus supplements pursuant to
Rule 424.

ITEM 2.  REGISTRATION INFORMATION AND EMPLOYEE PLAN ANNUAL INFORMATION.

         The documents containing the information specified in this Item 2 will
be sent or given to employees, officers, directors or others as specified by
Rule 428(b)(1). In accordance with the rules and regulations of the Commission
and the instructions to Form S-8, such documents are not being filed with the
Commission either as part of this Registration Statement or as prospectuses or
prospectus supplements pursuant to Rule 424. Such documents, together with the
documents incorporated by reference herein pursuant to Item 3 of Part II of this
Registration Statement on Form S-8, constitute a prospectus that meets the
requirements of Section 10(a) of the Securities Act, and are available, free of
charge, upon written or oral request as follows: Littelfuse, Inc., 800 East
Northwest Highway, Des Plaines, Illinois 60016, attention Secretary; Tel. No.:
(847) 824-1188.

                                     PART II

               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

ITEM 3.  INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

         The following documents which have been filed with the Commission by
the Company pursuant to the Securities Exchange Act of 1934 ("1934 Act") are
incorporated herein by reference:

                  (a) The Company's Annual Report on Form 10-K for the fiscal
         year ended December 31, 2005 (1934 Act File No. 0-20388).

                  (b) The Company's Quarterly Report on Form 10-Q for the fiscal
         quarter ended April 1, 2006 (1934 Act File No. 0-20388).

                  (c) The Company's Current Reports on Form 8-K filed on
         February 7, 2006, February 8, 2006, February 10, 2006, February 23,
         2006, March 1, 2006, March 6, 2006,

                                      II-1
March 7, 2006, March 10, 2006, March 20, 2006, May 5, 2006 (including
         as amended), May 9, 2006 and May 11, 2006 (excluding any portions of
         such reports that were furnished).

                  (d) The description of the Company's Common Stock which is
         contained in the Form 10: General Form for Registration of Securities
         pursuant to Section 12(b) or (g) of the 1934 Act filed with the
         Commission on July 7, 1992 (1934 Act File No. 0-20388).

         All documents subsequently filed by the Company pursuant to Sections
13(a), 13(c), 14 and 15(d) of the 1934 Act (excluding any portions of such
documents that were furnished), prior to the filing of a post-effective
amendment which indicates that all securities offered hereby have been sold or
which deregisters all such securities then remaining unsold, shall be deemed to
be incorporated by reference into this Registration Statement and to be a part
hereof from the date of filing such documents. Any statement contained in an
incorporated document shall be deemed to be modified or superseded to the extent
that a statement contained herein or in any subsequently filed incorporated
document modifies or supersedes such statement.

ITEM 4.  DESCRIPTION OF SECURITIES.

         Not applicable.

ITEM 5.  INTERESTS OF NAMED EXPERTS AND COUNSEL.

         The consolidated financial statements of Littelfuse, Inc. incorporated
by reference in Littelfuse, Inc.'s Annual Report (Form 10-K) for the year ended
December 31, 2005 (including the schedule appearing therein), and Littelfuse,
Inc. management's assessment of the effectiveness of internal control over
financial reporting as of December 31, 2005 included therein, have been audited
by Ernst & Young LLP, independent registered public accounting firm, as set
forth in their reports thereon, incorporated by reference therein, and
incorporated herein by reference. Such consolidated financial statements and
management's assessment are incorporated herein by reference in reliance upon
such reports given on the authority of such firm as experts in accounting and
auditing.

ITEM 6.  INDEMNIFICATION OF DIRECTORS AND OFFICERS

         Section 145 of the Delaware General Corporation Law ("DGCL") gives
Delaware corporations the power to indemnify present and former officers and
directors under certain circumstances. The Certificate of Incorporation of the
Company provides for indemnification by the Company to the fullest extent
permitted by Section 145 of the DGCL of certain persons (including officers and
directors) in connection with any threatened, pending or completed action, suit
or proceeding brought or threatened against such person by reason of his
position with the Company or service at the request of the Company. The
Certificate of Incorporation further provides that indemnification shall not be
exclusive of any rights to which those indemnified may be entitled under any
bylaw, agreement, vote of stockholders or disinterested directors or otherwise.

         In addition, the Company maintains a directors' and officers' liability
insurance policy to insure its liability under the above-described provision of
its Certificate of Incorporation and to insure its individual directors and
officers certain obligations not covered by such provisions.

                                      II-2
ITEM 8.  EXHIBITS

         The following exhibits are submitted herewith or incorporated by
reference herein.

EXHIBIT
NUMBER                                DESCRIPTION
-------                               -----------

  4.1       Littelfuse, Inc. Equity Incentive Compensation Plan (filed as
            Exhibit A to the Company's Proxy Statement for Annual Meeting of
            Stockholders to be held on May 5, 2006 (1934 Act File No. 0-20388),
            and incorporated herein by reference)

  4.2       Certificate of Incorporation of Littelfuse, Inc. (filed as Exhibit
            3.1 to the Company's Form 10-K for the fiscal year ended January 3,
            1998 (1934 Act File No. 0-20388), and incorporated herein by
            reference)

  4.3       Bylaws of Littelfuse, Inc. (filed as Exhibit 3(II) to the Company's
            Form 8-K/A dated May 5, 2006 (1934 Act File No. 0-20388), and
            incorporated herein by reference)

  5.1       Opinion of Chapman and Cutler LLP

 23.1       Consent of Chapman and Cutler LLP (included in Exhibit 5.1)

 23.2       Consent of Ernst & Young LLP

 24.1       Power of Attorney (set forth on page II-7 of this Registration
            Statement)

                                      II-3
ITEM 9.  UNDERTAKINGS

(a)      The undersigned registrant hereby undertakes:

         (1)      To file, during any period in which offers or sales are being
                  made, a post-effective amendment to this registration
                  statement

                  (i)      To include any prospectus required by Section
                           10(a)(3) of the Securities Act of 1933;

                  (ii)     To reflect in the prospectus any facts or events
                           arising after the effective date of the registration
                           statement (or the most recent post-effective
                           amendment thereof) which, individually or in the
                           aggregate, represent a fundamental change in the
                           information set forth in the registration statement.
                           Notwithstanding the foregoing, any increase or
                           decrease in volume of securities offered (if the
                           total dollar value of securities offered would not
                           exceed that which was registered) and any deviation
                           from the low or high end of the estimated maximum
                           offering range may be reflected in the form of
                           prospectus filed with the Commission pursuant to Rule
                           424(b) if, in the aggregate, the changes in volume
                           and price represent no more than a 20 percent change
                           in the maximum aggregate offering price set forth in
                           the "Calculation of Registration Fee" table in the
                           effective registration statement;

                  (iii)    To include any material information with respect to
                           the plan of distribution not previously disclosed in
                           the registration statement or any material change to
                           such information in the registration statement;

                  provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii) do
                  not apply if the information required to be included in a
                  post-effective amendment by those paragraphs is contained in
                  reports filed with or furnished to the Commission by the
                  registrant pursuant to Section 13 or Section 15(d) of the
                  Securities Exchange Act of 1934 that are incorporated by
                  reference in the registration statement.

         (2)      That, for the purpose of determining any liability under the
                  Securities Act of 1933, each such post-effective amendment
                  shall be deemed to be a new registration statement relating to
                  the securities offered therein, and the offering of such
                  securities at that time shall be deemed to be the initial bona
                  fide offering thereof.

         (3)      To remove from registration by means of a post-effective
                  amendment any of the securities being registered which remain
                  unsold at the termination of the offering.

(b)      The undersigned registrant hereby undertakes that, for purposes of
         determining any liability under the Securities Act of 1933, each filing
         of the registrant's annual report pursuant to Section 13(a) or Section
         15(d) of the Securities Exchange Act

                                      II-4
of 1934 (and, where applicable, each filing of an employee benefit
         plan's annual report pursuant to Section 15(d) of the Securities
         Exchange Act of 1934) that is incorporated by reference in the
         Registration Statement shall be deemed to be a new registration
         statement relating to the securities offered therein, and the offering
         of such securities at that time shall be deemed to be the initial bona
         fide offering thereof.

(c)      Insofar as indemnification for liabilities arising under the Securities
         Act of 1933 may be permitted to directors, officers and controlling
         persons of the registrant pursuant to the provisions described under
         Item 6 above, or otherwise, the registrant has been advised that in the
         opinion of the Commission such indemnification is against public policy
         as expressed in the Securities Act of 1933 and is, therefore,
         unenforceable. In the event that a claim for indemnification against
         such liabilities (other than the payment by the registrant of expenses
         incurred or paid by a director, officer or controlling person of the
         registrant in the successful defense of any action, suit or proceeding)
         is asserted by such director, officer or controlling person in
         connection with the securities being registered, the registrant will,
         unless in the opinion of its counsel the matter has been settled by
         controlling precedent, submit to a court of appropriate jurisdiction
         the question whether such indemnification by it is against public
         policy as expressed in the Securities Act of 1933 and will be governed
         by the final adjudication of such issue.

                                      II-5
SIGNATURES

         Pursuant to the requirements of the Securities Act of 1933, the
registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of Des Plaines, State of Illinois, on June 2, 2006.

                                        LITTELFUSE, INC.

                                        By:         /s/ Gordon Hunter
                                           -------------------------------------
                                                      Gordon Hunter,
                                                    Chairman, President
                                                and Chief Executive Officer

                                      II-6
POWER OF ATTORNEY

         Each person whose signature appears below hereby constitutes and
appoints Gordon Hunter and Philip G. Franklin and each of them, his true and
lawful attorneys-in-fact and agents, with full power and substitution and
resubstitution for him or her in his or her name, place and stead, in any and
all capacities to sign any and all pre-effective and/or post-effective
amendments to this Registration Statement and to file the same, with all
exhibits thereto, and other documents in connection therewith with the
Securities and Exchange Commission under the Securities Act of 1933.

         Pursuant to the requirements of the Securities Act of 1933, this
registration statement has been signed by the following persons in the
capacities indicated on May 22, 2006.

           SIGNATURE                                        TITLE
           ---------                                        -----

     /s/ Gordon Hunter                              Chairman, President
------------------------------                   and Chief Executive Officer
         Gordon Hunter                          (Principal executive officer)

   /s/ Philip G. Franklin                     Vice President, Operations Support
------------------------------                    and Chief Financial Officer
       Philip G. Franklin                          (Principal financial and
                                                     accounting officer)

    /s/ John P. Driscoll                                   Director
------------------------------
        John P. Driscoll

    /s/ Anthony Grillo                                     Director
------------------------------
        Anthony Grillo

    /s/ Bruce A. Karsh                                     Director
------------------------------
        Bruce A. Karsh

    /s/ John E. Major                                      Director
------------------------------
        John E. Major

   /s/ Ronald L. Schubel                                   Director
------------------------------
       Ronald L. Schubel

                                      II-7
EXHIBIT
NUMBER                                DESCRIPTION
-------                               -----------

  4.1       Littelfuse, Inc. Equity Incentive Compensation Plan (filed as
            Exhibit A to the Company's Proxy Statement for Annual Meeting of
            Stockholders to be held on May 5, 2006 (1934 Act File No. 0-20388),
            and incorporated herein by reference)

  4.2       Certificate of Incorporation of Littelfuse, Inc. (filed as Exhibit
            3.1 to the Company's Form 10-K for the fiscal year ended January 3,
            1998 (1934 Act File No. 0-20388), and incorporated herein by
            reference)

  4.3       Bylaws of Littelfuse, Inc. (filed as Exhibit 3(II) to the Company's
            Form 8-K/A dated May 5, 2006 (1934 Act File No. 0-20388), and
            incorporated herein by reference)

  5.1       Opinion of Chapman and Cutler LLP

 23.1       Consent of Chapman and Cutler LLP (included in Exhibit 5.1)

 23.2       Consent of Ernst & Young LLP

 24.1       Power of Attorney (set forth on page II-7 of this Registration
            Statement)

                                       E-1