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<TITLE>sv8</TITLE>
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<DIV style="width: 94%; margin-left: 3%"><!-- BEGIN LOGICAL PAGE -->


<DIV align="center" style="margin-left: 0%; margin-right: 0%; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
    As filed with the Securities and Exchange Commission on June 8, 2007
</DIV>



<DIV align="right" style="margin-left: 0%; margin-right: 0%; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
    Registration<FONT style="white-space: nowrap">No.
&#160;333-&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</FONT>
</DIV>


<DIV align="center" style="margin-left: 0%; margin-right: 0%; margin-top: 3pt; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
    <B>
    <CENTER style="font-size: 1pt; width: 100%; border-bottom: 2pt solid #000000"></CENTER><!-- callerid=128 iwidth=540 length=0 --></B>
</DIV>

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    <B><FONT style="font-size: 14pt"> UNITED STATES SECURITIES AND EXCHANGE COMMISSION </FONT></B>
</DIV>

<DIV align="center" style="margin-left: 0%; margin-right: 0%; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
    <B><FONT style="font-size: 12pt"> Washington, &#160;D.C. 20549</FONT></B>
</DIV>

<DIV style="margin-top: 3pt; font-size: 1pt">&nbsp;</DIV>


<DIV align="center" style="margin-left: 0%; margin-right: 0%; margin-top: 6pt; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
<FONT style="font-size: 18pt"><FONT style="white-space: nowrap"><B>FORM&#160;S-8</B></FONT></FONT>
</DIV>

<DIV align="center" style="margin-left: 0%; margin-right: 0%; margin-top: 12pt; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
    <FONT style="font-size: 12pt"><B>REGISTRATION STATEMENT</B></FONT>
</DIV>

<DIV align="center" style="margin-left: 0%; margin-right: 0%; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
    <B><FONT style="font-size: 12pt"> UNDER</FONT></B>
</DIV>

<DIV align="center" style="margin-left: 0%; margin-right: 0%; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
    <B><FONT style="font-size: 12pt">THE SECURITIES ACT OF 1933 </FONT></B>
</DIV>

<DIV style="margin-top: 3pt; font-size: 1pt">&nbsp;</DIV>

<DIV align="center" style="margin-left: 0%; margin-right: 0%; margin-top: 6pt; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
   <FONT style="font-size: 24pt"> <B>AVALON PHARMACEUTICALS, INC.</B></FONT>
</DIV>

<DIV align="center" style="margin-left: 0%; margin-right: 0%; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
    <FONT style="font-size: 10pt">(Exact name of registrant as specified in its charter)</FONT>
</DIV>

<DIV style="margin-top: 12pt; font-size: 1pt">&nbsp;</DIV>


<TABLE border="0" width="100%" align="center" cellpadding="0" cellspacing="0" style="font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
<!-- Table Width Row -->
<TR style="font-size: 1pt" valign="bottom">
    <TD width="47%">&nbsp;</TD>
    <TD width="6%">&nbsp;</TD>
    <TD width="47%">&nbsp; </TD>
</TR>
<TR valign="bottom">
<TD nowrap align="center" valign="top">
    <B><FONT style="font-size: 10pt">Delaware </FONT></B></TD>
<TD>&nbsp;</TD>
<TD nowrap align="center" valign="top">
    <B><FONT style="font-size: 10pt">52-2209310</FONT></B></TD>
</TR>
<TR valign="bottom">
<TD align="center" valign="top">
    <FONT style="font-size: 10pt">(State or other jurisdiction of <BR>
 incorporation or Organization) </FONT></TD>
<TD>&nbsp;</TD>
<TD align="center" valign="top">
    <FONT style="font-size: 10pt"> (I.R.S. Employer<BR>
Identification No. </FONT></TD>
</TR>
</TABLE>

<DIV style="margin-top: 12pt; font-size: 1pt">&nbsp;</DIV>

<TABLE border="0" width="100%" align="center" cellpadding="0" cellspacing="0" style="font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
<!-- Table Width Row -->
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    <TD width="47%">&nbsp;</TD>
    <TD width="4%">&nbsp;</TD>
    <TD width="47%">&nbsp;</TD>
</TR>
<TR valign="bottom">
<TD nowrap align="center" valign="top">
    <B><FONT style="font-size: 10pt">20358 Seneca Meadows Parkway,</FONT></B></TD>
<TD>&nbsp;</TD>
<TD nowrap align="center" valign="top">
    <B><FONT style="font-size: 10pt">&nbsp;</FONT></B>
</TD>
</TR>

<TR valign="bottom">
<TD nowrap align="center" valign="top">
    <B><FONT style="font-size: 10pt">Germantown, Maryland </FONT></B></TD>
<TD>&nbsp;</TD>
<TD nowrap align="center" valign="top">
    <B><FONT style="font-size: 10pt">20876</FONT></B></TD>
</TR>

<TR valign="bottom">
<TD align="center" valign="top">
    <FONT style="font-size: 10pt">(Address of Principal Executive Offices)</FONT>
</TD>
<TD>&nbsp;</TD>
<TD align="center" valign="top">
    <FONT style="font-size: 10pt">(Zip Code)</FONT></TD>
</TR>
</TABLE>



<DIV align="left" style="margin-left: 0%; margin-right: 0%; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">

</DIV>

<DIV style="margin-top: 12pt; font-size: 1pt">&nbsp;</DIV>


<DIV align="center" style="margin-left: 0%; margin-right: 0%; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
    <B> Avalon Pharmaceuticals, Inc. 2005 Omnibus Long-Term Incentive Plan </B><BR>
(Full title of the plan) </DIV>

<DIV style="margin-top: 12pt; font-size: 1pt">&nbsp;</DIV>

<DIV align="center" style="margin-left: 0%; margin-right: 0%; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
    <B> Kenneth C. Carter, Ph.D.<BR>
President and Chief Executive Officer<BR>
Avalon Pharmaceuticals, Inc. <BR>
20358 Seneca Meadows Parkway<BR>
Germantown, Maryland 20876</B>
</DIV>

<DIV align="center" style="margin-left: 0%; margin-right: 0%; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">(Name and address of agent for service)
</DIV>

<DIV style="margin-top: 12pt; font-size: 1pt">&nbsp;</DIV>

<DIV align="center" style="margin-left: 0%; margin-right: 0%; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
    <B>(301) 556-9900</B>
</DIV>

<DIV align="center" style="margin-left: 0%; margin-right: 0%; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
<FONT style="font-size: 10pt">(Telephone number, including area code, of agent for service) </FONT>
</DIV>

<DIV style="margin-top: 3pt; font-size: 1pt">&nbsp;</DIV>


<DIV style="margin-top: 12pt; font-size: 1pt">&nbsp;</DIV>

<DIV align="center" style="margin-left: 0%; margin-right: 0%; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
Copy to:</DIV>

<DIV align="center" style="margin-left: 0%; margin-right: 0%; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
    <B> Michael J. Silver<BR>
Hogan &#38; Hartson L.L.P. <BR>
111 South Calvert Street, 16th Floor<BR>
Baltimore, Maryland 21202<BR>
Telephone: (410) 659-2700<BR>
Telecopy: (410) 539-6981</B>
</DIV>


<DIV style="margin-top: 12pt; font-size: 1pt">&nbsp;</DIV>

<DIV align="center" style="margin-left: 0%; margin-right: 0%; font-size: 10pt; font-family: Arial, Helvetica; color: #000000; background: #FFFFFF">

    <B><FONT style="font-family: 'Times New Roman', Times">CALCULATION
    OF REGISTRATION FEE</FONT></B>
</DIV>

<DIV style="margin-top: 12pt; font-size: 1pt">&nbsp;</DIV>

<TABLE border="0" width="100%" align="center" cellpadding="0" cellspacing="0" style="font-size: 9pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
<!-- Table Width Row -->
<TR style="font-size: 1pt" valign="bottom">
    <TD width="40%">&nbsp;</TD>         <!-- colindex=01 type=maindata -->
    <TD width="1%">&nbsp;</TD>  <!-- colindex=02 type=gutterleft -->
    <TD width="1%">&nbsp;</TD>  <!-- colindex=02 type=gutterright -->
    <TD width="13%">&nbsp;</TD>         <!-- colindex=02 type=maindata -->
    <TD width="1%">&nbsp;</TD>  <!-- colindex=03 type=gutterleft -->
    <TD width="1%">&nbsp;</TD>  <!-- colindex=03 type=gutterright -->
    <TD width="13%">&nbsp;</TD>         <!-- colindex=03 type=maindata -->
    <TD width="1%">&nbsp;</TD>  <!-- colindex=04 type=gutterleft -->
    <TD width="1%">&nbsp;</TD>  <!-- colindex=04 type=gutterright -->
    <TD width="13%">&nbsp;</TD>         <!-- colindex=04 type=maindata -->
    <TD width="1%">&nbsp;</TD>  <!-- colindex=05 type=gutterleft -->
    <TD width="1%">&nbsp;</TD>  <!-- colindex=05 type=gutterright -->
    <TD width="13%">&nbsp;</TD>         <!-- colindex=05 type=maindata -->
</TR>

<TR style="font-size: 8pt" valign="bottom" align="center">
<TD nowrap align="center" valign="bottom" style="border-top: 3px double #000000">
    <B>Title of securities</B>
</TD>
<TD style="border-right: 1px solid #000000; padding-right: 2pt; border-top: 3px double #000000">
&nbsp;
</TD>
<TD style="border-top: 3px double #000000">
&nbsp;
</TD>
<TD nowrap align="center" valign="bottom" style="border-top: 3px double #000000">
    <B> Amount to be</B><BR>
</TD>
<TD style="border-right: 1px solid #000000; padding-right: 2pt; border-top: 3px double #000000">
&nbsp;
</TD>
<TD style="border-top: 3px double #000000">
&nbsp;
</TD>
<TD nowrap align="center" valign="bottom" style="border-top: 3px double #000000">
    <B>Proposed Maximum</B><BR>

</TD>
<TD style="border-right: 1px solid #000000; padding-right: 2pt; border-top: 3px double #000000">
&nbsp;
</TD>
<TD style="border-top: 3px double #000000">
&nbsp;
</TD>
<TD nowrap align="center" valign="bottom" style="border-top: 3px double #000000">
    <B>Proposed Maximum<BR>
    </B>
</TD>
<TD style="border-right: 1px solid #000000; padding-right: 2pt; border-top: 3px double #000000">
&nbsp;
</TD>
<TD style="border-top: 3px double #000000">
&nbsp;
</TD>
<TD nowrap align="center" valign="bottom" style="border-top: 3px double #000000">
    <B> Amount of<BR></B>
</TD>
</TR>



<TR style="font-size: 8pt" valign="bottom" align="center">
<TD nowrap align="center" valign="bottom">
    <B>to be registered </B></TD>
<TD style="border-right: 1px solid #000000; padding-right: 2pt">
&nbsp;</TD>
<TD>&nbsp;</TD>
<TD nowrap align="center" valign="bottom">
    <B>Registered</B></TD>
<TD style="border-right: 1px solid #000000; padding-right: 2pt">
&nbsp;</TD>
<TD>&nbsp;</TD>
<TD nowrap align="center" valign="bottom">
    <B>offering price per share (1)</B>
</TD>
<TD style="border-right: 1px solid #000000; padding-right: 2pt">
&nbsp;
</TD>
<TD>
&nbsp;
</TD>
<TD nowrap align="center" valign="bottom">
    <B>aggregate offering price (1)
</B>
</TD>
<TD style="border-right: 1px solid #000000; padding-right: 2pt">
&nbsp;
</TD>
<TD>
&nbsp;
</TD>
<TD nowrap align="center" valign="bottom">
    <B>registration fee (1)</B>
</TD>
</TR>

<TR valign="bottom">
<TD align="left" valign="top" style="border-top: 1px solid #000000">
    <FONT style="font-size: 9pt"> Common Stock, par value $0.01 per share (2)
    </FONT>
</TD>
<TD style="border-right: 1px solid #000000; padding-right: 2pt; border-top: 1px solid #000000">
&nbsp;</TD>
<TD style="border-top: 1px solid #000000">
&nbsp;
</TD>
<TD nowrap align="center" valign="bottom" style="border-top: 1px solid #000000">
800,000 shares (3)</TD>
<TD style="border-right: 1px solid #000000; padding-right: 2pt; border-top: 1px solid #000000">&nbsp;</TD>
<TD style="border-top: 1px solid #000000">
&nbsp;</TD>
<TD nowrap align="center" valign="bottom" style="border-top: 1px solid #000000">
$5.35
</TD>
<TD style="border-right: 1px solid #000000; padding-right: 2pt; border-top: 1px solid #000000">
&nbsp;
</TD>
<TD style="border-top: 1px solid #000000">
&nbsp;
</TD>
<TD nowrap align="center" valign="bottom" style="border-top: 1px solid #000000">
    <FONT style="font-size: 9pt">$4,280,000    </FONT>
</TD>
<TD style="border-right: 1px solid #000000; padding-right: 2pt; border-top: 1px solid #000000">
&nbsp;
</TD>
<TD style="border-top: 1px solid #000000">
&nbsp;
</TD>
<TD nowrap align="center" valign="bottom" style="border-top: 1px solid #000000">
    <FONT style="font-size: 9pt"> $131.40    </FONT>
</TD>
</TR>
<TR valign="bottom">
<TD nowrap align="left" valign="bottom" style="border-top: 3px double #000000">
&nbsp;
</TD>
<TD style="border-top: 3px double #000000">
&nbsp;
</TD>
<TD style="border-top: 3px double #000000">
&nbsp;
</TD>
<TD nowrap align="left" valign="bottom" style="border-top: 3px double #000000">
&nbsp;
</TD>
<TD style="border-top: 3px double #000000">
&nbsp;
</TD>
<TD style="border-top: 3px double #000000">
&nbsp;
</TD>
<TD nowrap align="left" valign="bottom" style="border-top: 3px double #000000">
&nbsp;
</TD>
<TD style="border-top: 3px double #000000">
&nbsp;
</TD>
<TD style="border-top: 3px double #000000">
&nbsp;
</TD>
<TD nowrap align="left" valign="bottom" style="border-top: 3px double #000000">
&nbsp;
</TD>
<TD style="border-top: 3px double #000000">
&nbsp;
</TD>
<TD style="border-top: 3px double #000000">
&nbsp;
</TD>
<TD nowrap align="left" valign="bottom" style="border-top: 3px double #000000">
&nbsp;
</TD>
</TR>
</TABLE>





<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">

<TR style="font-size: 1px">
    <TD width="3%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="96%">&nbsp;</TD>
</TR>

<TR>
    <TD align="right" valign="top">
    <FONT style="font-size: 9pt">(1)
    </FONT></TD>
    <TD></TD>
    <TD valign="bottom">
    <FONT style="font-size: 9pt">Estimated pursuant to Rule 457(c) and (h) of the Securities Act of 1933, as amended (the &#147;Securities Act&#148;) solely for purposes of calculating the registration fee, based on the average of the high and low prices reported for the shares on The Nasdaq Global Market on June 6, 2007.
    </FONT></TD>
</TR>

<TR style="line-height: 3pt; font-size: 1pt"><TD>&nbsp;</TD></TR>

<TR>
    <TD align="right" valign="top">
    <FONT style="font-size: 9pt">(2)
    </FONT></TD>
    <TD></TD>
    <TD valign="bottom">
    <FONT style="font-size: 9pt"> Includes Series C Junior Participating Preferred Stock Purchase Rights attached thereto, for which no separate fee is payable pursuant to Rule 457(i) of the Securities Act.
    </FONT></TD>
</TR>

<TR style="line-height: 3pt; font-size: 1pt"><TD>&nbsp;</TD></TR>

<TR>
    <TD align="right" valign="top">
    <FONT style="font-size: 9pt">(3)
    </FONT></TD>
    <TD></TD>
    <TD valign="bottom">
    <FONT style="font-size: 9pt">  Pursuant to Rule 416 under the Securities Act, this Registration Statement shall also cover any additional shares of common stock which become issuable under the above-named plan by reason of any stock dividend, stock split, recapitalization or any other similar transaction effected without the receipt of consideration which results in an increase in the number of our outstanding shares of common stock.</FONT></TD>
</TR>



</TABLE>

<DIV style="margin-top: 6pt; font-size: 1pt">&nbsp;</DIV>

<DIV align="left" style="margin-left: 0%; margin-right: 0%; text-indent: 5%; font-size: 9pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
</DIV>

<DIV style="margin-top: 4pt; font-size: 1pt">&nbsp;</DIV>

<CENTER style="font-size: 1pt; width: 100%; border-bottom: 1pt solid #000000"></CENTER><!-- callerid=999 iwidth=528 length=0 -->

<CENTER style="font-size: 1pt; width: 100%; border-bottom: 2pt solid #000000"></CENTER><!-- callerid=999 iwidth=528 length=0 -->

<P align="left" style="font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">

</DIV><!-- END LOGICAL PAGE -->


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<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>
<DIV style="width: 87%; margin-left: 6%"><!-- BEGIN LOGICAL PAGE -->

<DIV align="center" style="margin-left: 0%; margin-right: 0%; font-size: 10pt; font-family: Arial, Helvetica; color: #000000; background: #FFFFFF">

    <B><FONT style="font-family: 'Times New Roman', Times">EXPLANATORY NOTE </FONT></B>
</DIV>

<DIV style="margin-top: 6pt; font-size: 1pt">&nbsp;</DIV>

<DIV align="left" style="margin-left: 0%; margin-right: 0%; text-indent: 4%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
This Registration Statement on Form S-8 for Avalon Pharmaceuticals, Inc.
(the &#147;Company&#148;) is being filed pursuant to General Instruction E of Form S-8 to
register 800,000 additional shares of common stock for issuance under
the Company&#146;s 2005
Omnibus Long-Term Incentive Plan (the &#147;Plan&#148;). The Company previously registered
(i)&nbsp;989,738 shares of common stock for issuance under the Plan, along with 546,123 shares
of common stock for issuance upon the exercise of outstanding options
granted under the Company&#146;s
Amended and Restated 1999 Stock Plan, under a Registration Statement on Form S-8 (File No. 333-128904),
filed with the Securities and Exchange Commission on October 7, 2005 (the &#147;Initial Registration
Statement&#148;), and (ii)&nbsp;an additional 591,844 shares of common stock for issuance under the Plan
under a Registration Statement on Form S-8 (File No. 333-138408) filed with the Securities and Exchange
Commission on November 3, 2006 (together with the Initial Registration Statement, the &#147;Prior
Registration Statements&#148;). The contents of the Prior Registration Statements
are incorporated herein by reference. </DIV>

<DIV style="margin-top: 12pt; font-size: 1pt">&nbsp;</DIV>

<DIV align="center" style="margin-left: 0%; margin-right: 0%; text-indent: 4%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
    <B><FONT style="font-family: 'Times New Roman', Times">PART II<BR>
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
</FONT></B>
</DIV>


<DIV style="margin-top: 12pt; font-size: 1pt">&nbsp;</DIV>

<DIV align="left" style="margin-left: 0%; margin-right: 0%; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
    <B><FONT style="font-family: 'Times New Roman', Times"> Item 8. Exhibits.
</FONT></B>
</DIV>

<DIV style="margin-top: 12pt; font-size: 1pt">&nbsp;</DIV>

<DIV align="left" style="margin-left: 0%; margin-right: 0%; text-indent: 4%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">Reference is made to the attached Exhibit Index, which is incorporated by reference herein.
</DIV>

<DIV style="margin-top: 12pt; font-size: 1pt">&nbsp;</DIV>

<DIV align="center" style="margin-left: 0%; margin-right: 0%; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
 <B><FONT style="font-family: 'Times New Roman', Times">SIGNATURES
</FONT></B>
</DIV>

<DIV style="margin-top: 12pt; font-size: 1pt">&nbsp;</DIV>

<DIV align="left" style="margin-left: 0%; margin-right: 0%; text-indent: 4%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
Pursuant to the requirements of the Securities Act of 1933, the registrant certifies that it has reasonable
grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this
Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the
County of Montgomery, State of Maryland, on June&nbsp;8, 2007.
</DIV>





 <DIV align="center" style="margin-top: 12pt">
<TABLE cellspacing="0" border="0" cellpadding="0" width="100%" style="font-size: 10pt">
<TR style="font-size: 6pt">
    <TD width="6%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="18%">&nbsp;</TD>
    <TD width="22%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="37%">&nbsp;</TD>
    <TD width="12%">&nbsp;</TD>
</TR>

<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD colspan="3" align="left"><B>AVALON PHARMACEUTICALS, INC.</B></TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>
<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>
<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">By: </TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;/s/ Kenneth C. Carter</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR style="font-size: 1px">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left" style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">Name: Kenneth C. Carter, Ph.D. </TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
   <TD nowrap align="left">Title: President and Chief Executive Officer</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 12pt; font-size: 1pt">&nbsp;</DIV>

<DIV align="center" style="margin-left: 0%; margin-right: 0%; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
<B>POWER OF ATTORNEY </B>
</DIV>



<DIV style="margin-top: 12pt; font-size: 1pt">&nbsp;</DIV>

<DIV align="left" style="margin-left: 0%; margin-right: 0%; text-indent: 4%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Kenneth C. Carter and Thomas G. David and each of them his or her true and lawful attorney-in-fact and agent, with full power of substitution and resubstitution, for him or her and in his or her name, place and stead, in any and all capacities (including his or her capacity as a director and/or officer) to sign any or all amendments (including post-effective amendments) to this registration statement, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorney-in-fact and agent full power and authority to do and perform each and every act and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorney-in-fact and agent or his substitute or substitutes, may lawfully do or cause to be done by virtue hereof.
</DIV>



<P align="center" style="font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
    <BR>
    &nbsp;
</DIV><!-- END LOGICAL PAGE -->
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<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>
<DIV style="width: 87%; margin-left: 6%"><!-- BEGIN LOGICAL PAGE -->



<DIV style="margin-top: 12pt; font-size: 1pt">&nbsp;</DIV>

<DIV align="left" style="margin-left: 0%; margin-right: 0%; text-indent: 4%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed by the following persons in the capacities indicated on June&nbsp;8, 2007.
 </DIV>
<DIV align="center" style="margin-top: 12pt">
<TABLE cellspacing="0" border="0" cellpadding="0" width="100%" style="font-size: 10pt">
<TR style="font-size: 6pt">
    <TD width="45%">&nbsp;</TD>
    <TD width="10%">&nbsp;</TD>
    <TD width="45%">&nbsp;</TD>
</TR>

<TR style="font-size: 8pt">
    <TD nowrap align="center"><B>Signature</B></TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="center"><B>Title</B></TD>
</TR>

<TR style="font-size: 1px">
    <TD nowrap align="left" style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left" style="border-top: 1px solid #000000">&nbsp;</TD>
</TR>

<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left"> President, Chief Executive Officer and Director </TD>
</TR>

<TR valign="top">
    <TD nowrap align="center">&nbsp;/s/ Kenneth C. Carter</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left"> <I>(Principal Executive Officer)</I>
 </TD>
</TR>

<TR style="font-size: 1px">
    <TD nowrap align="left" style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
  <TD nowrap align="center"> Kenneth C. Carter, Ph.D.</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>
<TR valign="top">
  <TD nowrap align="center"> /s/ Gary Lessing</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">Chief Financial Officer <I>(Principal Financial Officer)</I>
 </TD>
</TR>

<TR style="font-size: 1px">
    <TD nowrap align="left" style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
  <TD nowrap align="center"> Gary Lessing</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
  <TD nowrap align="center"> /s/ Glen A. Farmer</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left"> Controller <I>(Principal Accounting Officer)</I>
 </TD>
</TR>

<TR style="font-size: 1px">
    <TD nowrap align="left" style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
  <TD nowrap align="center">Glen A. Farmer</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
  <TD nowrap align="center"> /s/ David S. Kabakoff</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">Director</TD>
</TR>

<TR style="font-size: 1px">
    <TD nowrap align="left" style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
  <TD nowrap align="center"> David S. Kabakoff, Ph.D.</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>


<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>
<TR valign="top">
  <TD nowrap align="center"> /s/ Bradley G. Lorimier</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">Director</TD>
</TR>

<TR style="font-size: 1px">
    <TD nowrap align="left" style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
  <TD nowrap align="center">Bradley G. Lorimier</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>
<TR valign="top">
  <TD nowrap align="center"> /s/ Ivor Royston</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left"> Director </TD>
</TR>

<TR style="font-size: 1px">
    <TD nowrap align="left" style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
  <TD nowrap align="center">Ivor Royston, M.D.</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>
<TR valign="top">
  <TD nowrap align="center"> /s/ William A. Scott</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">Director</TD>
</TR>

<TR style="font-size: 1px">
    <TD nowrap align="left" style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
  <TD nowrap align="center">William A. Scott, Ph.D.</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>
<TR valign="top">
  <TD nowrap align="center"> /s/ Alan G. Walton</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">Chairman of the Board of Directors</TD>
</TR>

<TR style="font-size: 1px">
    <TD nowrap align="left" style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
  <TD nowrap align="center">Alan G. Walton, Ph.D., D.Sc.</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
  <TD nowrap align="center"> /s/ William H. Washecka</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">Director</TD>
</TR>

<TR style="font-size: 1px">
    <TD nowrap align="left" style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
  <TD nowrap align="center">William H. Washecka</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

</TABLE>
</DIV>


<P align="center" style="font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
    <BR>
    &nbsp;
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<DIV style="width: 87%; margin-left: 6%"><!-- BEGIN LOGICAL PAGE -->



<DIV style="margin-top: 12pt; font-size: 1pt">&nbsp;</DIV>

<DIV align="center" style="margin-left: 0%; margin-right: 0%; text-indent: 0%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: #FFFFFF">
<B>EXHIBIT INDEX </B></DIV>
<DIV align="center" style="margin-top: 12pt">
<TABLE cellspacing="0" border="0" cellpadding="0" width="100%" style="font-size: 10pt">
<TR style="font-size: 6pt">
    <TD width="7%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="90%">&nbsp;</TD>
</TR>

<TR style="font-size: 8pt">
    <TD nowrap align="center"><B>Exhibit</B></TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR style="font-size: 8pt">
    <TD nowrap align="center"><B>Number</B></TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left"><B>Description</B></TD>
</TR>

<TR style="font-size: 1px">
    <TD nowrap align="left" style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left" style="border-top: 1px solid #000000">&nbsp;</TD>
</TR>

<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>


<TR valign="top">
    <TD nowrap align="right">4.1</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD align="left">Specimen Common Stock Certificate, incorporated by
reference to Exhibit 4.1 of the Registrant&#146;s S-1 Registration
Statement (File No. 333-124565).</TD>
</TR>

<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>

<TR valign="top">
    <TD nowrap align="right">10.1</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD align="left">Avalon Pharmaceuticals, Inc. 2005
Omnibus Long-Term Incentive Plan, as amended, incorporated
by reference to Exhibit 10.1 of the Registrant&#146;s
Current Report on Form 8-K filed on June 7, 2007.</TD>
</TR>


<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>


<TR valign="top">
    <TD nowrap align="right">5.1</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">Opinion of Hogan &#38; Hartson L.L.P.</TD>
</TR>


<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>


<TR valign="top">
    <TD nowrap align="right">23.1</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">Consent of Ernst &#38; Young LLP.
</TD>
</TR>

<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>


<TR valign="top">
    <TD nowrap align="right">23.2 </TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">Consent of Hogan &#38; Hartson, L.L.P. (included in Exhibit 5.1)</TD>
</TR>

<TR valign="top">
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left">&nbsp;</TD>
</TR>



<TR valign="top">
    <TD nowrap align="right">24.1</TD>
    <TD nowrap align="left">&nbsp;</TD>
    <TD nowrap align="left"> Powers of Attorney (included in Part II)</TD>
</TR>

</TABLE>
</DIV>






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</BODY>
</HTML>
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sv8
As filed with the Securities and Exchange Commission on June 8, 2007
Registration
No.
 333-
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington,  D.C. 20549
FORM S-8
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
AVALON PHARMACEUTICALS, INC.
(Exact name of registrant as specified in its charter)
Delaware
52-2209310
(State or other jurisdiction of
incorporation or Organization)
(I.R.S. Employer
Identification No.
20358 Seneca Meadows Parkway,
Germantown, Maryland
20876
(Address of Principal Executive Offices)
(Zip Code)
Avalon Pharmaceuticals, Inc. 2005 Omnibus Long-Term Incentive Plan
(Full title of the plan)
Kenneth C. Carter, Ph.D.
President and Chief Executive Officer
Avalon Pharmaceuticals, Inc.
20358 Seneca Meadows Parkway
Germantown, Maryland 20876
(Name and address of agent for service)
(301) 556-9900
(Telephone number, including area code, of agent for service)
Copy to:
Michael J. Silver
Hogan & Hartson L.L.P.
111 South Calvert Street, 16th Floor
Baltimore, Maryland 21202
Telephone: (410) 659-2700
Telecopy: (410) 539-6981
CALCULATION
    OF REGISTRATION FEE
Title of securities
Amount to be
Proposed Maximum
Proposed Maximum
Amount of
to be registered
Registered
offering price per share (1)
aggregate offering price (1)
registration fee (1)
Common Stock, par value $0.01 per share (2)
800,000 shares (3)
$5.35
$4,280,000
$131.40
(1)
Estimated pursuant to Rule 457(c) and (h) of the Securities Act of 1933, as amended (the "Securities Act") solely for purposes of calculating the registration fee, based on the average of the high and low prices reported for the shares on The Nasdaq Global Market on June 6, 2007.
(2)
Includes Series C Junior Participating Preferred Stock Purchase Rights attached thereto, for which no separate fee is payable pursuant to Rule 457(i) of the Securities Act.
(3)
Pursuant to Rule 416 under the Securities Act, this Registration Statement shall also cover any additional shares of common stock which become issuable under the above-named plan by reason of any stock dividend, stock split, recapitalization or any other similar transaction effected without the receipt of consideration which results in an increase in the number of our outstanding shares of common stock.
EXPLANATORY NOTE
This Registration Statement on Form S-8 for Avalon Pharmaceuticals, Inc.
(the "Company") is being filed pursuant to General Instruction E of Form S-8 to
register 800,000 additional shares of common stock for issuance under
the Company's 2005
Omnibus Long-Term Incentive Plan (the "Plan"). The Company previously registered
(i) 989,738 shares of common stock for issuance under the Plan, along with 546,123 shares
of common stock for issuance upon the exercise of outstanding options
granted under the Company's
Amended and Restated 1999 Stock Plan, under a Registration Statement on Form S-8 (File No. 333-128904),
filed with the Securities and Exchange Commission on October 7, 2005 (the "Initial Registration
Statement"), and (ii) an additional 591,844 shares of common stock for issuance under the Plan
under a Registration Statement on Form S-8 (File No. 333-138408) filed with the Securities and Exchange
Commission on November 3, 2006 (together with the Initial Registration Statement, the "Prior
Registration Statements"). The contents of the Prior Registration Statements
are incorporated herein by reference.
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 8. Exhibits.
Reference is made to the attached Exhibit Index, which is incorporated by reference herein.
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, the registrant certifies that it has reasonable
grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this
Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the
County of Montgomery, State of Maryland, on June 8, 2007.
AVALON PHARMACEUTICALS, INC.
By:
/s/ Kenneth C. Carter
Name: Kenneth C. Carter, Ph.D.
Title: President and Chief Executive Officer
POWER OF ATTORNEY
KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Kenneth C. Carter and Thomas G. David and each of them his or her true and lawful attorney-in-fact and agent, with full power of substitution and resubstitution, for him or her and in his or her name, place and stead, in any and all capacities (including his or her capacity as a director and/or officer) to sign any or all amendments (including post-effective amendments) to this registration statement, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorney-in-fact and agent full power and authority to do and perform each and every act and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorney-in-fact and agent or his substitute or substitutes, may lawfully do or cause to be done by virtue hereof.
Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed by the following persons in the capacities indicated on June 8, 2007.
Signature
Title
President, Chief Executive Officer and Director
/s/ Kenneth C. Carter
(Principal Executive Officer)
Kenneth C. Carter, Ph.D.
/s/ Gary Lessing
Chief Financial Officer
(Principal Financial Officer)
Gary Lessing
/s/ Glen A. Farmer
Controller
(Principal Accounting Officer)
Glen A. Farmer
/s/ David S. Kabakoff
Director
David S. Kabakoff, Ph.D.
/s/ Bradley G. Lorimier
Director
Bradley G. Lorimier
/s/ Ivor Royston
Director
Ivor Royston, M.D.
/s/ William A. Scott
Director
William A. Scott, Ph.D.
/s/ Alan G. Walton
Chairman of the Board of Directors
Alan G. Walton, Ph.D., D.Sc.
/s/ William H. Washecka
Director
William H. Washecka
EXHIBIT INDEX
Exhibit
Number
Description
4.1
Specimen Common Stock Certificate, incorporated by
reference to Exhibit 4.1 of the Registrant's S-1 Registration
Statement (File No. 333-124565).
10.1
Avalon Pharmaceuticals, Inc. 2005
Omnibus Long-Term Incentive Plan, as amended, incorporated
by reference to Exhibit 10.1 of the Registrant's
Current Report on Form 8-K filed on June 7, 2007.
5.1
Opinion of Hogan & Hartson L.L.P.
23.1
Consent of Ernst & Young LLP.
23.2
Consent of Hogan & Hartson, L.L.P. (included in Exhibit 5.1)
24.1
Powers of Attorney (included in Part II)