<HTML>
<HEAD>
<TITLE>s-8</TITLE>
</HEAD>
<BODY bgcolor="#FFFFFF">
<!-- PAGEBREAK -->

<P align="right">Registration No.&nbsp;333-____

<P align="center"><B>UNITED STATES<BR>
SECURITIES AND EXCHANGE COMMISSION<BR>
Washington, D.C. 20549<BR>
FORM S-8<BR>
REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933</B>

<P align="center"><U>DIGENE CORPORATION</U>
<BR>
<B>(Exact name of registrant as specified in its charter)</B>

<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="100%" align="center">
<TR valign="bottom">
        <TD width="50%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="45%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD align="left" valign="top"><FONT size="2">Delaware</FONT></TD>
        <TD></TD>
        <TD  align="center" valign="top"><FONT size="2">
52-1536128</FONT></TD>
</TR>
<TR valign="bottom">
        <TD align="left" valign="top"><FONT size="2"><HR size="1" width="44%"></FONT></TD>
        <TD></TD>
        <TD  align="center" valign="top"><FONT size="2"><HR size="1" width="30%"></FONT></TD>
</TR>
<TR valign="bottom">
        <TD align="left" valign="top"><FONT size="2"><B>(State or other jurisdiction of<BR>
incorporation or organization)</B></FONT></TD>
        <TD></TD>
        <TD  align="center" valign="top"><FONT size="2">
<B>(I.R.S. Employer<BR>
Identification No.)</B></FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD><TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD><TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD align="left" valign="top"><FONT size="2">1201 Clopper Road<BR>
Gaithersburg, Maryland</FONT></TD>
        <TD></TD>
        <TD  align="center" valign="top"><FONT size="2">
<BR>20878</FONT></TD>
</TR>

<TR valign="bottom">
        <TD align="left" valign="top"><FONT size="2"><HR size="1" width="57%"></FONT></TD>
        <TD></TD>
        <TD  align="center" valign="top"><FONT size="2"><HR size="1" width="20%"></FONT></TD>
</TR>
<TR valign="bottom">
        <TD align="left" valign="top"><FONT size="2"><B>(Address of Principal Executive Offices)</B></FONT></TD>
        <TD></TD>
        <TD  align="center" valign="top"><FONT size="2">
<B>(Zip Code)</B></FONT></TD>
</TR>
</TABLE>
</CENTER>
<P align="center"><U>Digene Corporation Amended and Restated 1999 Incentive Plan</U>
<BR><B>(Full title of the plan)</B>

<P align="center">Charles M. Fleischman<BR>
President and Chief Operating Officer<BR>
1201 Clopper Road<BR>
<U>Gaithersburg, Maryland 20878</U><BR>
<B>(Name and address of agent for service)</B><BR>
<U>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
(301)&nbsp;944-7000
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U><br>
<B>(Telephone number, including area code, of agent for service)</B>

<P align="center">with a copy to:<BR>
Morris Cheston, Jr., Esquire<BR>
Ballard Spahr Andrews &#38; Ingersoll, LLP<BR>
1735 Market Street<BR>
Philadelphia, Pennsylvania 19103-7599<BR>
(215)&nbsp;665-8500

<P align="center"><B><U>CALCULATION OF REGISTRATION FEE</U></B>

<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="75%" align="center">
<TR valign="bottom">
        <TD width="25%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="6%">&nbsp;</TD>
        <TD width="1%">&nbsp;</TD>
        <TD width="7%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="4%">&nbsp;</TD>
        <TD width="1%">&nbsp;</TD>
        <TD width="4%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="8%">&nbsp;</TD>
        <TD width="1%">&nbsp;</TD>
        <TD width="9%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="6%">&nbsp;</TD>
        <TD width="1%">&nbsp;</TD>
        <TD width="7%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD colspan="17"><HR size="1"></TD>
</TR>
<TR valign="bottom">
        <TD></TD>
        <TD></TD>
        <TD></TD>
        <TD></TD>
        <TD></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>Proposed</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>Proposed</B></FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><FONT size="2"><B>Title of</B></FONT></TD>
        <TD></TD>
        <TD></TD>
        <TD></TD>
        <TD></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>maximum</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>maximum</B></FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><FONT size="2"><B>securities</B></FONT></TD>
        <TD nowrap align="center" colspan="5"><FONT size="2"><B>Amount</B></FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>offering</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>aggregate</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>Amount of</B></FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><FONT size="2"><B>to be</B></FONT></TD>
        <TD nowrap align="center" colspan="5"><FONT size="2"><B>to be</B></FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>price per</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>offering</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>registration</B></FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><FONT size="2"><B>registered</B></FONT></TD>
        <TD nowrap align="center" colspan="5"><FONT size="2"><B>registered(1)</B></FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>share(2)</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>price(2)</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>fee</B></FONT></TD>
</TR>

<TR valign="bottom">
        <TD colspan="17"><HR size="1"></TD>
</TR>

<TR valign="bottom">
        <TD><FONT size="2">Common Stock,
par value $.01
per share</FONT></TD>
        <TD></TD>
        <TD></TD>
        <TD align="right"><FONT size="2">1,000,000</FONT></TD>
        <TD></TD>
        <TD></TD>
        <TD align="right"><FONT size="2">$</FONT></TD>
        <TD align="right"><FONT size="2">22.930</FONT></TD>
        <TD></TD>
        <TD></TD>
        <TD align="right"><FONT size="2">$</FONT></TD>
        <TD align="right"><FONT size="2">22,930,000</FONT></TD>
        <TD></TD>
        <TD></TD>
        <TD align="right"><FONT size="2">$</FONT></TD>
        <TD align="right"><FONT size="2">5,732.50</FONT></TD>
        <TD></TD>
</TR>

<TR valign="bottom">
        <TD colspan="17"><HR size="1"></TD>
</TR>
</TABLE>
</CENTER>
<P>


<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR valign="top">
      <TD width="1%" align="left">(1)</TD>
        <TD width="3%">&nbsp;</TD>
        <TD width="96%">In addition, pursuant to Rule&nbsp;416(a) under the Securities Act of 1933,
this registration statement shall be deemed to cover an indeterminate
number of additional shares of Common Stock issuable in the event the
number of outstanding shares of the Company is increased by stock split,
reclassification, stock dividend or the like.</TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="top">
      <TD width="1%" align="left">(2)</TD>
        <TD width="3%">&nbsp;</TD>
        <TD width="96%">Estimated solely for the purpose of calculating the registration fee. In
accordance with Rule&nbsp;457(h), the price shown is based upon the average of
the high and low price of the Company&#146;s Common Stock on
September&nbsp;21, 2001, as reported on the Nasdaq National Market for the Company&#146;s Common
Stock.</TD>
</TR>
</TABLE>
<P align="center">&nbsp;
<!-- PAGEBREAK -->
<P><HR noshade><P>




<P align="left"><B>PART I &#151;INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS</B>

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Part I and Items 4-7 and 9 of Part II of Digene Corporation&#146;s Registration
Statement on Form&nbsp;S-8 (File No.&nbsp;333-47782) are incorporated by reference herein
pursuant to Instruction E of Form&nbsp;S-8.

<P align="left"><B>PART II &#151;INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</B>

<TABLE cellspacing="0" border="0" cellpadding="0" width="100%" align="center">
<TR valign="bottom">
        <TD width="8%">&nbsp;</TD>
        <TD width="4%">&nbsp;</TD>
        <TD width="88%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD valign="top"><B>Item&nbsp;3.</B></TD>
        <TD></TD>
        <TD valign="top"><B>Incorporation of Certain Documents by Reference.</B></TD>
</TR>
</TABLE>

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The following documents filed with the Securities and Exchange Commission
(the &#147;Commission&#148;) pursuant to the Securities Exchange Act of 1934, as amended
(the &#147;Exchange Act&#148;) by Digene Corporation (the &#147;Company&#148;) (File No.&nbsp;0-28194)
or pursuant to the Securities Act of 1933, as amended (the &#147;Securities Act&#148;)
are incorporated herein by reference:

<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="75%" align="center">
<TR valign="bottom">
        <TD width="8%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="87%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD valign="top">(a)</TD>
        <TD></TD>
        <TD  align="left" valign="top">
Quarterly Report on Form&nbsp;10-Q for the fiscal
quarter ended March&nbsp;31, 2001;</TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top">(b)</TD>
        <TD></TD>
        <TD  align="left" valign="top">
Quarterly Report on Form&nbsp;10-Q for the fiscal
quarter ended December&nbsp;31, 2000;</TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top">(c)</TD>
        <TD></TD>
        <TD  align="left" valign="top">
Quarterly Report on Form&nbsp;10-Q for the fiscal
quarter ended September&nbsp;30, 2000;</TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top">(d)</TD>
        <TD></TD>
        <TD  align="left" valign="top">
Annual Report on Form&nbsp;10-K for the fiscal year
ended June&nbsp;30, 2000; and</TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top">(e)</TD>
        <TD></TD>
        <TD  align="left" valign="top">
Item&nbsp;1 of Registration Statement of the Company
on Form&nbsp;8-A dated April&nbsp;11, 1996.</TD>
</TR>
</TABLE>
</CENTER>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;All documents filed by the Company pursuant to Sections&nbsp;13(a), 13(c), 14
or 15(d) of the Exchange Act, after the date of this Registration Statement and
prior to the termination of the offering, shall be deemed to be incorporated by
reference herein and to be part hereof from the date of filing such documents.
Any statement contained herein or in a document incorporated by reference or
deemed to be incorporated by reference herein shall be deemed to be modified or
superseded for purposes of this Registration Statement to the extent that such
statement is modified or superseded by any other subsequently filed document
which is incorporated or is deemed to be incorporated by reference herein. Any
such statement so modified or superseded shall not be deemed, except as so
modified or superseded, to constitute a part of this Registration Statement.

<TABLE cellspacing="0" border="0" cellpadding="0" width="100%" align="center">
<TR valign="bottom">
        <TD width="8%">&nbsp;</TD>
        <TD width="4%">&nbsp;</TD>
        <TD width="88%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD valign="top"><B>Item&nbsp;8.</B></TD>
        <TD></TD>
        <TD valign="top"><B>Exhibits.</B></TD>
</TR>
</TABLE>

<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="90%" align="center">
<TR valign="bottom">
        <TD width="5%">&nbsp;</TD>
        <TD width="3%">&nbsp;</TD>
        <TD width="92%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD valign="top">4.1</TD>
        <TD></TD>
        <TD  align="left" valign="top">
Digene Corporation Amended and Restated 1999 Incentive Plan.</TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top">4.2</TD>
        <TD></TD>
        <TD  align="left" valign="top">
Specimen copy of Common Stock Certificate (incorporated by
reference to Exhibit&nbsp;4.1 to the Company&#146;s Registration Statement on
Form&nbsp;S-1, as amended (File No.&nbsp;333-2968)).</TD>
</TR>
</TABLE>
</CENTER>
<P align="center">2
<!-- PAGEBREAK -->
<P><HR noshade><P>

<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="90%" align="center">
<TR valign="bottom">
        <TD width="5%">&nbsp;</TD>
        <TD width="3%">&nbsp;</TD>
        <TD width="92%">&nbsp;</TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">5</FONT></TD>
        <TD></TD>
        <TD  align="left" valign="top">
Opinion of Ballard Spahr Andrews &#38; Ingersoll, LLP as to the
legality of the securities to be offered.</TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top">23.1</TD>
        <TD></TD>
        <TD  align="left" valign="top">
Consent of Ernst &#38; Young LLP.</TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top">23.2</TD>
        <TD></TD>
        <TD  align="left" valign="top">
Consent of Ballard Spahr Andrews &#38; Ingersoll, LLP (included
as part of Exhibit&nbsp;5).</TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top">24</TD>
        <TD></TD>
        <TD  align="left" valign="top">
Power of Attorney (included in signature page).</TD>
</TR>
</TABLE>
</CENTER>
<P align="center">3
<!-- PAGEBREAK -->
<P><HR noshade><P>

<P align="center"><B>SIGNATURES</B>

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act of 1933, the registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form&nbsp;S-8 and has duly caused this registration
statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of Gaithersburg, State of Maryland, on September&nbsp;26, 2001.

<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="40%" align="center">
<TR valign="bottom">
        <TD width="10%">&nbsp;</TD>
        <TD width="8%">&nbsp;</TD>
        <TD width="82%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD colspan="3" align="left" valign="top">DIGENE CORPORATION</TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top">By</TD>
        <TD></TD>
        <TD  align="left" valign="top">
<U>/s/ Charles M. Fleischman&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U><BR>
Charles M. Fleischman, President,<BR>
Chief Operating Officer and<BR>
Chief Financial Officer</TD>
</TR>
</TABLE>
</CENTER>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Each person whose signature appears below in so signing also makes,
constitutes and appoints Evan Jones and Charles M. Fleischman, and each of
them, his true and lawful attorney-in-fact, with full power of substitution,
for him in any and all capacities, to execute and cause to be filed with the
Securities and Exchange Commission any and all amendments and post-effective
amendments to this Registration Statement, with exhibits thereto and other
documents in connection therewith, and hereby ratifies and confirms all that
said attorney-in-fact or his substitute or substitutes may do or cause to be
done by virtue hereof.

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act of 1933, this
registration statement has been signed by the following persons in the
capacities and on the date indicated.

<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="100%" align="center">

<TR valign="bottom">
        <TD width="40%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="27%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="23%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><FONT size="2"><U>Signature</U></FONT></TD>
        <TD></TD>
        <TD nowrap align="center"><FONT size="2"><U>Title</U></FONT></TD>
        <TD></TD>
        <TD nowrap align="left"><FONT size="2"><U>Date</U></FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD><TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top">/s/ Evan Jones<BR>
<HR size="1">
<center>Evan Jones</center></TD>
        <TD></TD>
        <TD  align="left" valign="top">
Chairman and Chief
Executive Officer
(principal
executive officer)
</TD>
        <TD></TD>
        <TD nowrap align="left" valign="top">September 26, 2001</TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top">/s/ Charles M. Fleischman<BR>
<HR size="1">
<center>Charles M. Fleischman</center></TD>
        <TD></TD>
        <TD  align="left" valign="top">
President, Chief
Operating Officer,
Chief Financial
Officer and
Director (principal
financial officer)
</TD>
        <TD></TD>
        <TD nowrap align="left" valign="top">September 26, 2001</TD>
</TR>
</TABLE>
</CENTER>
<P align="center">4
<!-- PAGEBREAK -->
<P><HR noshade><P>

<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="100%" align="center">
<TR valign="bottom">
        <TD width="40%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="27%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="23%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD valign="top">/s/ Joseph P. Slattery<BR>
<HR size="1">
<center>Joseph P. Slattery</center></TD>
        <TD></TD>
        <TD  align="left" valign="top">
Vice President,
Finance<BR>
(principal
accounting officer)
</TD>
        <TD></TD>
        <TD  align="left" valign="top">September 26, 2001</TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top">/s/ Wayne T. Hockmeyer<BR>
<HR size="1">
<CENTER>Wayne T. Hockmeyer</CENTER></TD>
        <TD></TD>
        <TD  align="left" valign="top">
Director
</TD>
        <TD></TD>
        <TD  align="left" valign="top">September 26,  2001</TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top">/s/ John H. Landon<BR>
<HR size="1">
<CENTER>John H. Landon</CENTER></TD>
        <TD></TD>
        <TD  align="left" valign="top">
Director
</TD>
        <TD></TD>
        <TD  align="left" valign="top">September 26, 2001</TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top">/s/ Joseph M. Migliara<BR>
<HR size="1">
<CENTER>Joseph M. Migliara</CENTER></TD>
        <TD></TD>
        <TD  align="left" valign="top">
Director
</TD>
        <TD></TD>
        <TD  align="left" valign="top">September 26, 2001</TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top">/s/ John J. Whitehead<BR>
<HR size="1">
<CENTER>John J. Whitehead</CENTER></TD>
        <TD></TD>
        <TD  align="left" valign="top">
Director
</TD>
        <TD></TD>
        <TD  align="left" valign="top">September 26, 2001</TD>
</TR>
</TABLE>
</CENTER>
<P align="center">5
<!-- PAGEBREAK -->
<P><HR noshade><P>

<P align="center"><B>EXHIBIT INDEX</B>

<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="75%" align="center">
<TR valign="bottom">
        <TD width="8%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="87%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><u>Number</u></TD>
        <TD></TD>
        <TD nowrap align="center"><u>Exhibit</u></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD><TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top">4.1</TD>
        <TD></TD>
        <TD  align="left" valign="top">
Digene Corporation Amended and Restated 1999 Incentive Plan.</TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top">4.2</TD>
        <TD></TD>
        <TD  align="left" valign="top">
Specimen copy of Common Stock Certificate (incorporated by reference to
Exhibit&nbsp;4.1 to the Company&#146;s Registration Statement on Form&nbsp;S-1, as
amended (File No.&nbsp;333-2968)).</TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top">5</TD>
        <TD></TD>
        <TD  align="left" valign="top">
Opinion of Ballard Spahr Andrews &#38; Ingersoll, LLP as to the legality of
the securities to be offered.</TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top">23.1</TD>
        <TD></TD>
        <TD  align="left" valign="top">
Consent of Ernst &#38; Young LLP.</TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top">23.2</TD>
        <TD></TD>
        <TD  align="left" valign="top">
Consent of Ballard Spahr Andrews &#38; Ingersoll, LLP (included as part of
Exhibit&nbsp;5).</TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top">24</TD>
        <TD></TD>
        <TD  align="left" valign="top">
Power of Attorney (included in signature page).</TD>
</TR>
</TABLE>
</CENTER>

<P align="center">

</BODY>
</HTML>
[{"type": "S-8", "sequence": "1", "filename": "w53403s-8.htm", "description": "REGISTRATION STATEMENT, FORM S-8", "secsgml_size_bytes": 21671}]
{"company-data": {"conformed-name": "DIGENE CORP", "cik": "0001011582", "assigned-sic": "2835", "irs-number": "521536128", "state-of-incorporation": "DE", "fiscal-year-end": "0630"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-70196", "film-number": "1745030"}, "business-address": {"street1": "1201 CLOPPER ROAD", "city": "GAITHERSBURG", "state": "MD", "zip": "20878", "phone": "3019447000"}, "mail-address": {"street1": "2301 B BROADBIRCH DRIVE", "street2": "1201 CLOPPER ROAD", "city": "GAITHERSBURG", "state": "MD", "zip": "20904"}}
s-8
Registration No. 333-____
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-8
REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933
DIGENE CORPORATION
(Exact name of registrant as specified in its charter)
Delaware
52-1536128
(State or other jurisdiction of
incorporation or organization)
(I.R.S. Employer
Identification No.)
1201 Clopper Road
Gaithersburg, Maryland
20878
(Address of Principal Executive Offices)
(Zip Code)
Digene Corporation Amended and Restated 1999 Incentive Plan
(Full title of the plan)
Charles M. Fleischman
President and Chief Operating Officer
1201 Clopper Road
Gaithersburg, Maryland 20878
(Name and address of agent for service)
(301) 944-7000
(Telephone number, including area code, of agent for service)
with a copy to:
Morris Cheston, Jr., Esquire
Ballard Spahr Andrews & Ingersoll, LLP
1735 Market Street
Philadelphia, Pennsylvania 19103-7599
(215) 665-8500
CALCULATION OF REGISTRATION FEE
Proposed
Proposed
Title of
maximum
maximum
securities
Amount
offering
aggregate
Amount of
to be
to be
price per
offering
registration
registered
registered(1)
share(2)
price(2)
fee
Common Stock,
par value $.01
per share
1,000,000
$
22.930
$
22,930,000
$
5,732.50
(1)
In addition, pursuant to Rule 416(a) under the Securities Act of 1933,
this registration statement shall be deemed to cover an indeterminate
number of additional shares of Common Stock issuable in the event the
number of outstanding shares of the Company is increased by stock split,
reclassification, stock dividend or the like.
(2)
Estimated solely for the purpose of calculating the registration fee. In
accordance with Rule 457(h), the price shown is based upon the average of
the high and low price of the Company's Common Stock on
September 21, 2001, as reported on the Nasdaq National Market for the Company's Common
Stock.
PART I —INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS
Part I and Items 4-7 and 9 of Part II of Digene Corporation's Registration
Statement on Form S-8 (File No. 333-47782) are incorporated by reference herein
pursuant to Instruction E of Form S-8.
PART II —INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 3.
Incorporation of Certain Documents by Reference.
The following documents filed with the Securities and Exchange Commission
(the "Commission") pursuant to the Securities Exchange Act of 1934, as amended
(the "Exchange Act") by Digene Corporation (the "Company") (File No. 0-28194)
or pursuant to the Securities Act of 1933, as amended (the "Securities Act")
are incorporated herein by reference:
(a)
Quarterly Report on Form 10-Q for the fiscal
quarter ended March 31, 2001;
(b)
Quarterly Report on Form 10-Q for the fiscal
quarter ended December 31, 2000;
(c)
Quarterly Report on Form 10-Q for the fiscal
quarter ended September 30, 2000;
(d)
Annual Report on Form 10-K for the fiscal year
ended June 30, 2000; and
(e)
Item 1 of Registration Statement of the Company
on Form 8-A dated April 11, 1996.
All documents filed by the Company pursuant to Sections 13(a), 13(c), 14
or 15(d) of the Exchange Act, after the date of this Registration Statement and
prior to the termination of the offering, shall be deemed to be incorporated by
reference herein and to be part hereof from the date of filing such documents.
Any statement contained herein or in a document incorporated by reference or
deemed to be incorporated by reference herein shall be deemed to be modified or
superseded for purposes of this Registration Statement to the extent that such
statement is modified or superseded by any other subsequently filed document
which is incorporated or is deemed to be incorporated by reference herein. Any
such statement so modified or superseded shall not be deemed, except as so
modified or superseded, to constitute a part of this Registration Statement.
Item 8.
Exhibits.
4.1
Digene Corporation Amended and Restated 1999 Incentive Plan.
4.2
Specimen copy of Common Stock Certificate (incorporated by
reference to Exhibit 4.1 to the Company's Registration Statement on
Form S-1, as amended (File No. 333-2968)).
2
5
Opinion of Ballard Spahr Andrews & Ingersoll, LLP as to the
legality of the securities to be offered.
23.1
Consent of Ernst & Young LLP.
23.2
Consent of Ballard Spahr Andrews & Ingersoll, LLP (included
as part of Exhibit 5).
24
Power of Attorney (included in signature page).
3
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, the registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form S-8 and has duly caused this registration
statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of Gaithersburg, State of Maryland, on September 26, 2001.
DIGENE CORPORATION
By
/s/ Charles M. Fleischman
Charles M. Fleischman, President,
Chief Operating Officer and
Chief Financial Officer
Each person whose signature appears below in so signing also makes,
constitutes and appoints Evan Jones and Charles M. Fleischman, and each of
them, his true and lawful attorney-in-fact, with full power of substitution,
for him in any and all capacities, to execute and cause to be filed with the
Securities and Exchange Commission any and all amendments and post-effective
amendments to this Registration Statement, with exhibits thereto and other
documents in connection therewith, and hereby ratifies and confirms all that
said attorney-in-fact or his substitute or substitutes may do or cause to be
done by virtue hereof.
Pursuant to the requirements of the Securities Act of 1933, this
registration statement has been signed by the following persons in the
capacities and on the date indicated.
Signature
Title
Date
/s/ Evan Jones
Evan Jones
Chairman and Chief
Executive Officer
(principal
executive officer)
September 26, 2001
/s/ Charles M. Fleischman
Charles M. Fleischman
President, Chief
Operating Officer,
Chief Financial
Officer and
Director (principal
financial officer)
September 26, 2001
4
/s/ Joseph P. Slattery
Joseph P. Slattery
Vice President,
Finance
(principal
accounting officer)
September 26, 2001
/s/ Wayne T. Hockmeyer
Wayne T. Hockmeyer
Director
September 26,  2001
/s/ John H. Landon
John H. Landon
Director
September 26, 2001
/s/ Joseph M. Migliara
Joseph M. Migliara
Director
September 26, 2001
/s/ John J. Whitehead
John J. Whitehead
Director
September 26, 2001
5
EXHIBIT INDEX
Number
Exhibit
4.1
Digene Corporation Amended and Restated 1999 Incentive Plan.
4.2
Specimen copy of Common Stock Certificate (incorporated by reference to
Exhibit 4.1 to the Company's Registration Statement on Form S-1, as
amended (File No. 333-2968)).
5
Opinion of Ballard Spahr Andrews & Ingersoll, LLP as to the legality of
the securities to be offered.
23.1
Consent of Ernst & Young LLP.
23.2
Consent of Ballard Spahr Andrews & Ingersoll, LLP (included as part of
Exhibit 5).
24
Power of Attorney (included in signature page).