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<P align="center"><FONT size="2"><B>As filed with the Securities and Exchange Commission on July&nbsp;9, 2002</B>
</FONT>

<P align="right"><FONT size="2"><B>Registration No.&nbsp;333-<u>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U></B>
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<p>
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<P align="center"><FONT size="2"><B>SECURITIES AND EXCHANGE COMMISSION<BR>
Washington, D.C. 20549</B>
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<P align="center"><hr noshade width="15%" size="1">
<P align="center"><FONT size="2"><B>FORM S-8<BR>
REGISTRATION STATEMENT<BR>
Under the Securities Act of 1933</B>
</FONT>
<P align="center"><hr noshade width="15%" size="1">
<P align="center"><FONT size="2"><B>BIORELIANCE CORPORATION<BR>
(Exact name of registrant as specified in its charter)</B>
</FONT>

<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="65%">
<TR valign="bottom">
        <TD width="46%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="49%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD align="center"><FONT size="2"><B>Delaware</B><BR>
(State or other jurisdiction of<BR>
incorporation or organization)</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="center" valign="top"><FONT size="2">
<B>52-1541583</B><BR>
(I.R.S. Employer Identification No.)</FONT></TD>
</TR>
</TABLE>
</CENTER>
<P align="center"><FONT size="2"><B>14920 Broschart Road<BR>
Rockville, MD 20850</b><BR>
(Address of principal executive offices, including zip code)
</FONT>

<P align="center"><FONT size="2"><B>AMENDED AND RESTATED BIORELIANCE 1997 INCENTIVE PLAN</b><BR>
(Full title of the plans)
</FONT>

<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="65%">
<TR valign="bottom">
        <TD width="38%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="57%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="center" valign="top"><FONT size="2">
Copy to:</FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD align="center" valign="top"><FONT size="2"><B>Capers W. McDonald</B><BR>
BioReliance Corporation<BR>
14920 Broschart Road<BR>
Rockville, MD  20850<BR>
(301) 762-5260</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="center" valign="top"><FONT size="2">
<B>Lanae Holbrook</B><BR>
Fried, Frank, Harris, Shriver &#038; Jacobson<BR>
1001 Pennsylvania Avenue, N.W.<BR>
Washington, DC 20004<BR>
(202) 639-7303</FONT></TD>
</TR>
</TABLE>
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<P align="center"><FONT size="2">(Name, address and telephone number, including area code, of agent for service)<BR>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
</FONT>
<P align="center"><hr noshade width="15%" size="1">
<P align="center"><FONT size="2"><B>CALCULATION OF REGISTRATION FEE</B>
</FONT>

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<TABLE cellspacing="0" border="0" cellpadding="0" width="100%">
<TR valign="bottom">
        <TD width="45%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="3%">&nbsp;</TD>
        <TD width="1%">&nbsp;</TD>
        <TD width="3%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="2%">&nbsp;</TD>
        <TD width="1%">&nbsp;</TD>
        <TD width="2%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="8%">&nbsp;</TD>
        <TD width="1%">&nbsp;</TD>
        <TD width="9%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="2%">&nbsp;</TD>
        <TD width="1%">&nbsp;</TD>
        <TD width="2%">&nbsp;</TD>
</TR>
<tr><td colspan="17"><hr noshade size="4"></td></tr>

<TR valign="bottom">
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1"><B>Proposed Maximum</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1"><B>Proposed Maximum</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
</TR>
<TR valign="bottom">
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1"><B>Amount to be</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1"><B>offering price per</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1"><B>aggregate offering</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1"><B>Amount of</B></FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><FONT size="1"><B>Title of securities to be registered</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1"><B>registered</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1"><B>share(1)</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1"><B>price</B></FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1"><B>registration fee (2)</B></FONT></TD>
</TR>
<tr><td colspan="17"><hr noshade size="1"></td></tr>
<TR valign="bottom" bgcolor="#eeeeee">
        <TD><DIV style="margin-left:10px; text-indent:-10px"><FONT size="2">Common stock, $0.01 par value</FONT></DIV></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="right"><FONT size="2">178,483</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="right"><FONT size="2">$</FONT></TD>
        <TD align="right"><FONT size="2">12.90</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="right"><FONT size="2">$</FONT></TD>
        <TD align="right"><FONT size="2">2,302,430.70</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="right"><FONT size="2">$211.83</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
        <TD><DIV style="margin-left:10px; text-indent:-10px"><FONT size="2">Common stock, $0.01 par value</FONT></DIV></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="right"><FONT size="2">321,517</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="right"><FONT size="2">25.46</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="right"><FONT size="2">8,185,822.82</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="right"><FONT size="2">753.10</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom" bgcolor="#eeeeee">
        <TD><DIV style="margin-left:10px; text-indent:-10px"><FONT size="2">Total</FONT></DIV></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="right"><FONT size="2">500,000</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="right"><FONT size="2">$</FONT></TD>
        <TD align="right"><FONT size="2">10,488,253.52</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="right"><FONT size="2">$964.93</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>
<tr><td colspan="17"><hr noshade size="4"></td></tr>
</TABLE>
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<P>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR valign="top">
      <TD width="1%" align="left" nowrap><FONT size="2">(1)</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="96%"><FONT size="2">The proposed maximum offering price and registration fee for the
shares underlying the 178,483 options that have been granted under
the Amended and Restated BioReliance 1997 Incentive Plan were
calculated based on the weighted average exercise price of $12.90 of
the options granted. The proposed maximum offering price per share
and registration fee for the shares underlying the 321,517 options
not yet granted under the Amended and Restated BioReliance 1997
Incentive Plan were calculated based on the average of the high and
low prices of BioReliance&#146;s common stock on July&nbsp;1, 2002 as quoted on
Nasdaq Stock Market, in accordance with Rule&nbsp;457 (c)&nbsp;and (h).</FONT></TD>
</TR>
<TR>
        <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR valign="top">
      <TD width="1%" align="left" nowrap><FONT size="2">(2)</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="96%"><FONT size="2">This registration fee was previously paid in connection with prior
filings of BioReliance, Inc. with the Securities and Exchange
Commission.</FONT></TD>
</TR>
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<P align="center"><FONT size="2">&nbsp;</FONT>
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<P align="center"><FONT size="2"><B>EXPLANATORY NOTE</B>
</FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;This Registration Statement on Form&nbsp;S-8 registers 500,000 shares of common
stock of BioReliance Corporation that may be issued in connection with stock
options. These options have previously been or will be granted under the
Amended and Restated BioReliance 1997 Incentive Plan to employees, officers,
directors and consultants of BioReliance Corporation. The contents of
BioReliance&#146;s Registration Statement on Form&nbsp;S-8 (File No.&nbsp;333-34341) filed on
August&nbsp;26, 1997 is hereby incorporated by reference pursuant to Instruction E
of Form&nbsp;S-8.
</FONT>
<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<B>PART II. INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</B>
</FONT>
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<TABLE cellspacing="0" border="0" cellpadding="0" width="100%">
<TR valign="bottom">
        <TD width="9%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="86%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2"><B>Item 8.</B></FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
<B>Exhibits</B></FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2"><B>Exhibit<BR>
<u>No.</u></B></FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="bottom"><FONT size="2">
<B><u>Description of Exhibit</u></B></FONT></TD>
</TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">4.1*</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Amended and Restated BioReliance 1997 Incentive Plan.</FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">5.1*</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Opinion of Fried, Frank, Harris, Shriver &#038; Jacobson as to the validity of the<BR>
shares of common stock covered by the Registration Statement.</FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">23.1*</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Consent of PricewaterhouseCoopers LLP.</FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">23.2*</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Consent of Fried, Frank, Harris, Shriver &#038; Jacobson (included in Exhibit 5.1).</FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">24.1</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Powers of Attorney (included on signature page).</FONT></TD>
</TR>
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<P>
<HR size="1" width="18%" align="left" noshade>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR valign="top">
      <TD width="1%" align="left" nowrap><FONT size="2">*</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="96%"><FONT size="2">Filed herewith.</FONT></TD>
</TR>
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<P align="center"><FONT size="2">&nbsp;</FONT>
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<P align="center"><FONT size="2"><B>SIGNATURES</B>
</FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act of 1933, the Registrant
certifies that it has reasonable grounds to believe that it meets all the
requirements for filing on Form&nbsp;S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of Rockville, State of Maryland, on July&nbsp;9, 2002.
</FONT>
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<TABLE cellspacing="0" border="0" cellpadding="0" width="35%">
<TR valign="bottom">
        <TD width="100%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">BioReliance Corporation<BR>
(Registrant)</FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">By:     <u>/s/ Capers W. McDonald</u><BR>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Capers W. McDonald<BR>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;President and Chief Executive Officer</FONT></TD>
</TR>
</TABLE>
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<P align="center"><FONT size="2"><B>POWER OF ATTORNEY</B>
</FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The undersigned directors and officers of
BioReliance hereby constitute and appoint Sidney R. Knafel and Capers W. McDonald and
each of them, as his true and lawful attorneys-in-fact and agents, with full power to act
without the other and with full power of substitution and resubstitution, for him and in his
name, place and stead, in any and all capacities to sign any and all amendments (including
post-effective amendments) to this registration statement, and new registration statements
relating to this Form S-8, and to file the same with all exhibits thereto, and other documents
in connection therewith, with the Securities and Exchange Commission, granting unto said
attorneys-in-fact and agents, and each of them, full power and authority to do and perform each
and every act and thing requisite and necessary to be done in and about the premises, as fully
to all intents and purposes as he might or could do in person, hereby ratifying and confirming
all that said attorneys-in-fact and agents, or either of them, or their or his substitute or
substitutes, may lawfully do or cause to be done by virtue hereof.

</FONT>
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<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement on Form&nbsp;S-8 has been signed below by the following
persons in the capacities and on the dates indicated.
</FONT>
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<TABLE cellspacing="0" border="0" cellpadding="0" width="100%">
<TR valign="bottom">
        <TD width="36%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="42%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="12%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2"><B><u>SIGNATURE</u></B></FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
<B><u>TITLE</u></B>
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2"><B><u>DATE</u></B></FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2"><BR>
</FONT><HR size="1" noshade><FONT size="2">
Sidney R. Knafel</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Chairman of the Board
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">July ____, 2002</FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ Capers W. McDonald<BR>
</FONT><HR size="1" noshade><FONT size="2">
Capers W. McDonald</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
President, Chief Executive<BR>
Officer and a Director
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">July 8, 2002</FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ John L. Coker<BR>
</FONT><HR size="1" noshade><FONT size="2">
John L. Coker</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Chief Financial Officer; Chief
Accounting Officer; Vice
President&#150;Finance and
Administration; Treasurer and
Secretary
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">July 8, 2002</FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ William J. Gedale<BR>
</FONT><HR size="1" noshade><FONT size="2">
William J. Gedale</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Director
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">July 8, 2002</FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ Victoria Hamilton<BR>
</FONT><HR size="1" noshade><FONT size="2">
Victoria Hamilton</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Director
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">July 8, 2002</FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ Gordon J. Louttit<BR>
</FONT><HR size="1" noshade><FONT size="2">
Gordon J. Louttit</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Director
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">July 8, 2002</FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ Dr. Leonard Scherlis<BR>
</FONT><HR size="1" noshade><FONT size="2">
Dr. Leonard Scherlis</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Director
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">July 8, 2002</FONT></TD>
</TR>
</TABLE>
</CENTER>
<P align="center"><FONT size="2">&nbsp;</FONT>
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<P align="center"><FONT size="2">INDEX OF EXHIBITS
</FONT>
<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="100%">
<TR valign="bottom">
        <TD width="9%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="86%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2"><B>Exhibit<BR>
<u>No.</u></B></FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="bottom"><FONT size="2">
<B><u>Description of Exhibit</u></B></FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">4.1*</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Amended and Restated BioReliance 1997 Incentive Plan.</FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">5.1*</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Opinion of Fried, Frank, Harris, Shriver &#038; Jacobson as to the validity of the<BR>
shares of common stock covered by the Registration Statement.</FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">23.1*</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Consent of PricewaterhouseCoopers LLP.</FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">23.2*</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Consent of Fried, Frank, Harris, Shriver &#038; Jacobson (included in Exhibit 5.1).</FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">24.1</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Powers of Attorney (included on signature page).</FONT></TD>
</TR>
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      <TD width="1%" align="left" nowrap><FONT size="2">*</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="96%"><FONT size="2">Filed herewith.</FONT></TD>
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[{"type": "S-8", "sequence": "1", "filename": "w62088sv8.htm", "description": "S-8", "secsgml_size_bytes": 23459}]
{"company-data": {"conformed-name": "BIORELIANCE CORP", "cik": "0001036629", "assigned-sic": "8731", "irs-number": "521541583", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-92136", "film-number": "02698805"}, "business-address": {"street1": "C/O MICROBIOLOGICAL ASSOCIATES INC", "street2": "9900 BLACKWELL RD", "city": "ROCKVILLE", "state": "MD", "zip": "20850", "phone": "3017381000"}, "mail-address": {"street1": "C/O MICROBIOLOGICAL ASSOCIATES INC", "street2": "9900 BLACKWELL RD", "city": "ROCKVILLE", "state": "MD", "zip": "20850"}}
sv8
As filed with the Securities and Exchange Commission on July 9, 2002
Registration No. 333-
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-8
REGISTRATION STATEMENT
Under the Securities Act of 1933
BIORELIANCE CORPORATION
(Exact name of registrant as specified in its charter)
Delaware
(State or other jurisdiction of
incorporation or organization)
52-1541583
(I.R.S. Employer Identification No.)
14920 Broschart Road
Rockville, MD 20850
(Address of principal executive offices, including zip code)
AMENDED AND RESTATED BIORELIANCE 1997 INCENTIVE PLAN
(Full title of the plans)
Copy to:
Capers W. McDonald
BioReliance Corporation
14920 Broschart Road
Rockville, MD  20850
(301) 762-5260
Lanae Holbrook
Fried, Frank, Harris, Shriver & Jacobson
1001 Pennsylvania Avenue, N.W.
Washington, DC 20004
(202) 639-7303
(Name, address and telephone number, including area code, of agent for service)
CALCULATION OF REGISTRATION FEE
Proposed Maximum
Proposed Maximum
Amount to be
offering price per
aggregate offering
Amount of
Title of securities to be registered
registered
share(1)
price
registration fee (2)
Common stock, $0.01 par value
178,483
$
12.90
$
2,302,430.70
$211.83
Common stock, $0.01 par value
321,517
25.46
8,185,822.82
753.10
Total
500,000
$
10,488,253.52
$964.93
(1)
The proposed maximum offering price and registration fee for the
shares underlying the 178,483 options that have been granted under
the Amended and Restated BioReliance 1997 Incentive Plan were
calculated based on the weighted average exercise price of $12.90 of
the options granted. The proposed maximum offering price per share
and registration fee for the shares underlying the 321,517 options
not yet granted under the Amended and Restated BioReliance 1997
Incentive Plan were calculated based on the average of the high and
low prices of BioReliance's common stock on July 1, 2002 as quoted on
Nasdaq Stock Market, in accordance with Rule 457 (c) and (h).
(2)
This registration fee was previously paid in connection with prior
filings of BioReliance, Inc. with the Securities and Exchange
Commission.
EXPLANATORY NOTE
This Registration Statement on Form S-8 registers 500,000 shares of common
stock of BioReliance Corporation that may be issued in connection with stock
options. These options have previously been or will be granted under the
Amended and Restated BioReliance 1997 Incentive Plan to employees, officers,
directors and consultants of BioReliance Corporation. The contents of
BioReliance's Registration Statement on Form S-8 (File No. 333-34341) filed on
August 26, 1997 is hereby incorporated by reference pursuant to Instruction E
of Form S-8.
PART II. INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 8.
Exhibits
Exhibit
No.
Description of Exhibit
4.1*
Amended and Restated BioReliance 1997 Incentive Plan.
5.1*
Opinion of Fried, Frank, Harris, Shriver & Jacobson as to the validity of the
shares of common stock covered by the Registration Statement.
23.1*
Consent of PricewaterhouseCoopers LLP.
23.2*
Consent of Fried, Frank, Harris, Shriver & Jacobson (included in Exhibit 5.1).
24.1
Powers of Attorney (included on signature page).
*
Filed herewith.
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, the Registrant
certifies that it has reasonable grounds to believe that it meets all the
requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of Rockville, State of Maryland, on July 9, 2002.
BioReliance Corporation
(Registrant)
By:
/s/ Capers W. McDonald
Capers W. McDonald
President and Chief Executive Officer
POWER OF ATTORNEY
The undersigned directors and officers of
BioReliance hereby constitute and appoint Sidney R. Knafel and Capers W. McDonald and
each of them, as his true and lawful attorneys-in-fact and agents, with full power to act
without the other and with full power of substitution and resubstitution, for him and in his
name, place and stead, in any and all capacities to sign any and all amendments (including
post-effective amendments) to this registration statement, and new registration statements
relating to this Form S-8, and to file the same with all exhibits thereto, and other documents
in connection therewith, with the Securities and Exchange Commission, granting unto said
attorneys-in-fact and agents, and each of them, full power and authority to do and perform each
and every act and thing requisite and necessary to be done in and about the premises, as fully
to all intents and purposes as he might or could do in person, hereby ratifying and confirming
all that said attorneys-in-fact and agents, or either of them, or their or his substitute or
substitutes, may lawfully do or cause to be done by virtue hereof.
Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement on Form S-8 has been signed below by the following
persons in the capacities and on the dates indicated.
SIGNATURE
TITLE
DATE
Sidney R. Knafel
Chairman of the Board
July ____, 2002
/s/ Capers W. McDonald
Capers W. McDonald
President, Chief Executive
Officer and a Director
July 8, 2002
/s/ John L. Coker
John L. Coker
Chief Financial Officer; Chief
Accounting Officer; Vice
President–Finance and
Administration; Treasurer and
Secretary
July 8, 2002
/s/ William J. Gedale
William J. Gedale
Director
July 8, 2002
/s/ Victoria Hamilton
Victoria Hamilton
Director
July 8, 2002
/s/ Gordon J. Louttit
Gordon J. Louttit
Director
July 8, 2002
/s/ Dr. Leonard Scherlis
Dr. Leonard Scherlis
Director
July 8, 2002
INDEX OF EXHIBITS
Exhibit
No.
Description of Exhibit
4.1*
Amended and Restated BioReliance 1997 Incentive Plan.
5.1*
Opinion of Fried, Frank, Harris, Shriver & Jacobson as to the validity of the
shares of common stock covered by the Registration Statement.
23.1*
Consent of PricewaterhouseCoopers LLP.
23.2*
Consent of Fried, Frank, Harris, Shriver & Jacobson (included in Exhibit 5.1).
24.1
Powers of Attorney (included on signature page).
*
Filed herewith.