As Filed with the Securities and Exchange Commission on October 21, 2004

                                                     Registration No. 333-______

                UNITED STATES SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
               --------------------------------------------------

                                    FORM S-8
                             REGISTRATION STATEMENT
                           THE SECURITIES ACT OF 1933
               --------------------------------------------------

                              DELCATH SYSTEMS, INC.
        -----------------------------------------------------------------
             (Exact name of registrant as specified in its charter)


                    Delaware                               06-1245881
      --------------------------------------         ----------------------
         (State or other jurisdiction of                (I.R.S. Employer
         incorporation or organization)               Identification No.)

               1100 Summer Street
              Stamford, Connecticut                         06905
      --------------------------------------          -------------------
          (Address of Principal Executive                 (Zip Code)
                     Offices)

                             2000 Stock Option Plan
                             2001 Stock Option Plan
                            2004 Stock Incentive Plan
                            -------------------------
                            (Full title of the plans)

                                   M. S. Koly
                      President and Chief Executive Officer
                              Delcath Systems, Inc.
                               1100 Summer Street
                                    3rd Floor
                           Stamford, Connecticut 06905
                           ---------------------------
                     (Name and address of agent for service)

                                 (203) 323-8668
          (Telephone number, including area code of agent for service)

                                    Copy to:
                                 Paul G. Hughes
                               Murtha Cullina LLP
                        Two Whitney Avenue, P.O. Box 704
                        New Haven, Connecticut 06503-0704



<PAGE>


                         CALCULATION OF REGISTRATION FEE
<TABLE>
<CAPTION>

==========================================================================================================
                                                  Proposed Maximum   Proposed Maximum
   Title of Securities     Amount to be            Offering Price    Aggregate Offering      Amount of
     to be Registered     Registered (1)(2)           Per Share          Price (3)        Registration Fee

----------------------------------------------------------------------------------------------------------

<S>                       <C>                           <C>             <C>                   <C>
 Common Stock, $0.01
      par value           4,077,300 shares              (3)             $7,092,289            $899
==========================================================================================================
</TABLE>


(1)  Includes an indeterminate number of shares of Common Stock, par value $0.01
     of Delcath Systems, Inc. that may be issuable by reason of stock splits,
     stock dividends or similar transactions. In addition, pursuant to Rule
     416(c) under the Securities Act of 1933, this Registration Statement also
     covers an indeterminate number of interests to be offered or sold pursuant
     to the employee benefit plans described herein.

(2)  Includes an aggregate of 1,077,300 shares that may be sold under the 2000
     Stock Option Plan, and the 2001 Stock Option Plan; and 3,000,000 shares
     which may be offered or sold under the 2004 Stock Incentive Plan.

(3)  For shares that may be sold under the 2000 Stock Option Plan and the 2001
     Stock Option Plan, the offering price is based on the exercise price of the
     outstanding options of $1,302,289. For shares which may be offered or sold
     under the 2004 Stock Incentive Plan, estimated in accordance with Rule
     457(h)(1) under the Securities Act of 1933, as amended, solely for the
     purpose of calculating the registration fee; the price used is the closing
     price of the Common Stock of $1.93 on October 20, 2004, as reported by
     the Nasdaq SmallCap Market.




<PAGE>





                                     PART I

              INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS

     In accordance with the Note to Part I of the Registration Statement on Form
S-8, the document(s) containing the information specified in Part I of the
Registration Statement on Form S-8 is not being filed with the Commission either
as part of this Registration Statement or as prospectuses or prospectus
supplements pursuant to Rule 424 under the Securities Act of 1933.



<PAGE>



                                     PART II

               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

Item 3. Incorporation of Documents by Reference.

     The following documents filed by the Company with the SEC pursuant to the
Securities Exchange Act of 1934 (the "Exchange Act") are incorporated by
reference:

     (a) the Company's Annual Report on Form 10-KSB for the year ended December
31, 2003, filed on March 30, 2004;

     (b) the Company's definitive Proxy Statement dated April 29, 2004
distributed in connection with the Company's Annual Meeting of Shareholders held
on June 15, 2004;

     (c) the Company's Quarterly Report on Form 10-QSB for the quarter ended
March 31, 2004, filed on May 17, 2004;

     (d) the Company's Quarterly Report on Form 10-QSB for the quarter ended
June 30, 2004, filed on August 12, 2004;

     (e) the Company's Current Report on Form 8-K dated September 30, 2004; and

     (f) the description of the Company's common stock contained under the
caption "Description of Our Capital Stock and Other Securities - Units" in the
Prospectus included in the Company's Registration Statement on Form SB-2 (No.
333-101661), declared effective on May 15, 2003.

     All documents that the Company files with the SEC pursuant to Sections
13(a), 13(c), 14 or 15(d) of the Securities Exchange Act of 1934 after the date
hereof and prior to the filing of a post-effective amendment to this
registration statement that indicates that all the common stock offered has been
sold, or which deregisters all common stock then remaining unsold hereunder,
shall be incorporated by reference into this registration statement and to be a
part hereof (and of the prospectus(es)) from the date of filing of such
documents. Any statement contained in the prospectus(es) will be deemed to be
modified or superseded for purposes of this registration statement to the extent
that a statement contained in any subsequently filed document which also is or
is deemed to be incorporated by reference herein modifies or supersedes such
statement. Any such statement so modified or superseded will not be deemed,
except as so modified or superseded, to constitute a part of this registration
statement.


Item 8. Exhibits.

Exhibit                          Description
  No.
3.1  Amended and Restated Certificate of Incorporation of the Company, as
     amended to June 16, 2004 (incorporated by reference to Exhibit 3(i) to the
     Company's Quarterly Report on Form 10-QSB for the quarter ended June 30,
     2004)

3.2  Amended and Restated By-laws of the Company (incorporated by reference to
     Exhibit 3.2 to Amendment No. 1 to the Company's Registration Statement on
     Form SB-2 (Registration No. 333-39470))


                                      II-1


<PAGE>



4.1  Warrant Agreement, dated as of January 5, 2001, by and between Delcath
     Systems, Inc. and Euroland Marketing Solutions, Ltd. (incorporated by
     reference to Exhibit 4.5 to the Company's Annual Report on Form 10-KSB for
     the year ended December 31, 2000 (Commission File No. 001-16133))

4.2  Warrant No. W-2 to purchase up to 150,000 units granted to Euroland
     Marketing Services, Ltd. (incorporated by reference to Exhibit 4.6 to the
     Company's Annual Report on Form 10-KSB for the year ended December 31, 2000
     (Commission File No. 001-16133))

4.3  Rights Agreement, dated October 30, 2001, by and between Delcath Systems,
     Inc. and American Stock Transfer & Trust Company, as Rights Agent
     (incorporated by reference to Exhibit 4.7 to the Company's Form 8-A dated
     November 12, 2001 (Commission File No. 001-16133))

4.4  Form of Warrant Agreement by and between Delcath Systems, Inc. and Whale
     Securities Co., L.P. (incorporated by reference to Exhibit 4.2 to Amendment
     No. 5 to the Company's Registration Statement on Form SB-2 (Registration
     No. 333-39470))

4.5  Form of Warrant Agent Agreement by and among Delcath Systems, Inc., Whale
     Securities Co., L.P., and American Stock Transfer & Trust Company, as
     warrant agent (incorporated by reference to Exhibit 4.3 to Amendment No. 5
     to the Company's Registration Statement on Form SB-2 (Registration No.
     333-39470))

4.6  Form of Underwriter's Unit Warrant Agreement between Delcath Systems, Inc.
     and Roan/Meyers Associates L.P. (incorporated by reference to Exhibit 4.1
     to Amendment No. 1 to the Company's Registration Statement on Form SB-2
     (Registration No. 333-101661)).

4.7  Specimen 2003 Warrant (incorporated by reference to Exhibit 4.2 to
     Amendment No. 1 to the Company's Registration Statement on Form SB-2
     (Registration No. 333-101661))

4.8  Form of Warrant Agent Agreement by and between Delcath Systems, Inc. and
     American Stock Transfer & Trust Company, as warrant agent, with respect to
     the 2003 Warrants (incorporated by reference to Exhibit 4.8 to Amendment
     No. 3 to the Company's Registration Statement on Form SB-2 (Registration
     No. 333-101661))

5.1  Opinion of Murtha Cullina LLP

23.1 Consent of Eisner LLP

23.2 Consent of Murtha Cullina LLP (included in Exhibit 5.1)

24   Power of attorney of certain officers and directors of the Company

99.1 2000 Stock Option Plan (incorporated by reference to Exhibit 10.3 to the
     Company's Registration Statement on Form SB-2 (Registration No. 333-39470))


                                      II-2


<PAGE>



99.2 2001 Stock Option Plan (incorporated by reference to Exhibit 10.12 to
     Amendment No. 1 to the Company's Annual Report on Form 10-KSB for the year
     ended December 31, 2001 (Commission File No. 001-16133))

99.3 2004 Stock Incentive Plan (incorporated by reference to Exhibit B to the
     Company's definitive Proxy Statement dated April 29, 2004 (Commission File
     No. 001-16133))

Item 9. Undertakings.

     (a) The Company hereby undertakes:

     (1) To file, during any period in which offers or sales are being made, a
post-effective amendment to this Registration Statement:

     (i) to include any prospectus required by Section 10(a)(3) of the
Securities Act;

     (ii) to reflect in the prospectus any facts or events arising after the
effective date of this Registration Statement (or the most recent post-effective
amendment hereof) which, individually or in the aggregate, represent a
fundamental change in the information set forth in this Registration Statement;

     (iii) to include any material information with respect to the plan of
distribution not previously disclosed in this Registration Statement or any
material change to such information in this Registration Statement;

provided, however, that the undertakings set forth in paragraphs (i) and (ii)
above do not apply if the information required to be included in a
post-effective amendment by those paragraphs is contained in periodic reports
filed with or furnished to the SEC by the Company pursuant to Section 13 or
Section 15(d) of the Exchange Act that are incorporated by reference in this
Registration Statement.

     (2) That, for the purpose of determining any liability under the Securities
Act, each such post-effective amendment shall be deemed to be a new registration
statement relating to the securities offered therein, and the offering of such
securities at that time shall be deemed to be the initial bona fide offering
thereof.

     (3) To remove from registration by means of a post-effective amendment any
of the securities being registered hereby which remain unsold at the termination
of the offering.

     (b) The Company hereby undertakes that, for purposes of determining any
liability under the Securities Act, each filing of the Company's annual report
pursuant to Section 13(a) or 15(d) of the Exchange Act (and, where applicable,
each filing of an employee benefit plan's annual report pursuant to Section
15(d) of the Exchange Act) that is incorporated by reference in the Registration
Statement shall be deemed to be a new registration statement relating to the
securities offered therein, and the offering of such securities at that time
shall be deemed to be the initial bona fide offering thereof.

     (h) Insofar as indemnification for liabilities arising under the Securities
Act may be permitted to directors, officers and controlling persons of the
Company pursuant to the foregoing provisions, or otherwise, the Company has been
advised that in the opinion of the SEC such indemnification is against public
policy as expressed in the Securities Act and is, therefore, unenforceable. In
the event that a claim for indemnification against such liabilities (other than
the payment by the Company of expenses incurred or paid by a director or officer
or controlling person of the Company in the successful defense of any action,
suit or proceeding) is asserted by such director, officer or controlling person
in connection with the securities being


                                      II-3


<PAGE>


registered, the Company will, unless in the opinion of its counsel the matter
has been settled by controlling precedent, submit to a court of appropriate
jurisdiction the question of whether such indemnification by it is against
public policy as expressed in the Securities Act and will be governed by the
final adjudication of such issue.


                                      II-4


<PAGE>




                                   SIGNATURES

     Pursuant to the requirements of the Securities Act of 1933, as amended, the
registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of Stamford, State of Connecticut on October 21, 2004.

                                       Delcath Systems, Inc.


                                       By:         /s/ M. S Koly
                                           ----------------------------------
                                       Name:    M. S Koly
                                       Title:   President and Chief Executive
                                                Officer

     Pursuant to the requirements of the Securities Act of 1933, this
registration statement has been signed by the following persons in the
capacities and on the date indicated.

Name                    Title
----                    -----
M. S. Koly           President and Chief Executive)
                     Officer and Director         )
                     (Principal Executive Officer )
                                                  )
Paul M. Feinstein    Chief Financial Officer      )
                     (Principal Financial Officer))   By: /s/ M. S. Koly
                                                  )       --------------
Samuel Herschkowitz  Chairman and Director        )       Attorney-in-Fact
                                                  )
Mark A.Corigliano    Director                     )   Dated: October 21, 2004
                                                  )
Daniel Isdaner       Director                     )
                                                  )
Victor Nevins        Director                     )


                                      II-5


<PAGE>





                                 EXHIBIT INDEX


Exhibit                         Description
 No.
3.1  Amended and Restated Certificate of Incorporation of the Company, as
     amended to June 16, 2004 (incorporated by reference to Exhibit 3(i) to the
     Company's Quarterly Report on Form 10-QSB for the quarter ended June 30,
     2004)

3.2  Amended and Restated By-laws of the Company (incorporated by reference to
     Exhibit 3.2 to Amendment No. 1 to the Company's Registration Statement on
     Form SB-2 (Registration No. 333-39470))

4.1  Warrant Agreement, dated as of January 5, 2001, by and between Delcath
     Systems, Inc. and Euroland Marketing Solutions, Ltd. (incorporated by
     reference to Exhibit 4.5 to the Company's Annual Report on Form 10-KSB for
     the year ended December 31, 2000 (Commission File No. 001-16133))

4.2  Warrant No. W-2 to purchase up to 150,000 units granted to Euroland
     Marketing Services, Ltd. (incorporated by reference to Exhibit 4.6 to the
     Company's Annual Report on Form 10-KSB for the year ended December 31, 2000
     (Commission File No. 001-16133))

4.3  Rights Agreement, dated October 30, 2001, by and between Delcath Systems,
     Inc. and American Stock Transfer & Trust Company, as Rights Agent
     (incorporated by reference to Exhibit 4.7 to the Company's Form 8-A dated
     November 12, 2001 (Commission File No. 001-16133))

4.4  Form of Warrant Agreement by and between Delcath Systems, Inc. and Whale
     Securities Co., L.P. (incorporated by reference to Exhibit 4.2 to Amendment
     No. 5 to the Company's Registration Statement on Form SB-2 (Registration
     No. 333-39470))

4.5  Form of Warrant Agent Agreement by and among Delcath Systems, Inc., Whale
     Securities Co., L.P., and American Stock Transfer & Trust Company, as
     warrant agent (incorporated by reference to Exhibit 4.3 to Amendment No. 5
     to the Company's Registration Statement on Form SB-2 (Registration No.
     333-39470))

4.6  Form of Underwriter's Unit Warrant Agreement between Delcath Systems, Inc.
     and Roan/Meyers Associates L.P. (incorporated by reference to Exhibit 4.1
     to Amendment No. 1 to the Company's Registration Statement on Form SB-2
     (Registration No. 333-101661)).

4.7  Specimen 2003 Warrant (incorporated by reference to Exhibit 4.2 to
     Amendment No. 1 to the Company's Registration Statement on Form SB-2
     (Registration No. 333-101661))

4.8  Form of Warrant Agent Agreement by and between Delcath Systems, Inc. and
     American Stock Transfer & Trust Company, as warrant agent, with respect to
     the 2003 Warrants (incorporated by reference to Exhibit 4.8 to Amendment
     No. 3 to the Company's Registration Statement on Form SB-2 (Registration
     No. 333-101661))

5.1  Opinion of Murtha Cullina LLP


<PAGE>


23.1 Consent of Eisner LLP

23.2 Consent of Murtha Cullina LLP (included in Exhibit 5.1)

24   Power of attorney of certain officers and directors of the Company

99.1 2000 Stock Option Plan (incorporated by reference to Exhibit 10.3 to the
     Company's Registration Statement on Form SB-2 (Registration No. 333-39470))

99.2 2001 Stock Option Plan (incorporated by reference to Exhibit 10.12 to
     Amendment No. 1 to the Company's Annual Report on Form 10-KSB for the year
     ended December 31, 2001 (Commission File No. 001-16133))

99.3 2004 Stock Incentive Plan (incorporated by reference to Exhibit B to the
     Company's definitive Proxy Statement dated April 29, 2004 (Commission File
     No. 001-16133))
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As Filed with the Securities and Exchange Commission on October 21, 2004

                                                     Registration No. 333-______

                UNITED STATES SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
               --------------------------------------------------

                                    FORM S-8
                             REGISTRATION STATEMENT
                           THE SECURITIES ACT OF 1933
               --------------------------------------------------

                              DELCATH SYSTEMS, INC.
        -----------------------------------------------------------------
             (Exact name of registrant as specified in its charter)

                    Delaware                               06-1245881
      --------------------------------------         ----------------------
         (State or other jurisdiction of                (I.R.S. Employer
         incorporation or organization)               Identification No.)

               1100 Summer Street
              Stamford, Connecticut                         06905
      --------------------------------------          -------------------
          (Address of Principal Executive                 (Zip Code)
                     Offices)

                             2000 Stock Option Plan
                             2001 Stock Option Plan
                            2004 Stock Incentive Plan
                            -------------------------
                            (Full title of the plans)

                                   M. S. Koly
                      President and Chief Executive Officer
                              Delcath Systems, Inc.
                               1100 Summer Street
                                    3rd Floor
                           Stamford, Connecticut 06905
                           ---------------------------
                     (Name and address of agent for service)

                                 (203) 323-8668
          (Telephone number, including area code of agent for service)

                                    Copy to:
                                 Paul G. Hughes
                               Murtha Cullina LLP
                        Two Whitney Avenue, P.O. Box 704
                        New Haven, Connecticut 06503-0704
CALCULATION OF REGISTRATION FEE
==========================================================================================================
                                                  Proposed Maximum   Proposed Maximum
   Title of Securities     Amount to be            Offering Price    Aggregate Offering      Amount of
     to be Registered     Registered (1)(2)           Per Share          Price (3)        Registration Fee

----------------------------------------------------------------------------------------------------------
Common Stock, $0.01
      par value           4,077,300 shares              (3)             $7,092,289            $899
==========================================================================================================
(1)  Includes an indeterminate number of shares of Common Stock, par value $0.01
     of Delcath Systems, Inc. that may be issuable by reason of stock splits,
     stock dividends or similar transactions. In addition, pursuant to Rule
     416(c) under the Securities Act of 1933, this Registration Statement also
     covers an indeterminate number of interests to be offered or sold pursuant
     to the employee benefit plans described herein.

(2)  Includes an aggregate of 1,077,300 shares that may be sold under the 2000
     Stock Option Plan, and the 2001 Stock Option Plan; and 3,000,000 shares
     which may be offered or sold under the 2004 Stock Incentive Plan.

(3)  For shares that may be sold under the 2000 Stock Option Plan and the 2001
     Stock Option Plan, the offering price is based on the exercise price of the
     outstanding options of $1,302,289. For shares which may be offered or sold
     under the 2004 Stock Incentive Plan, estimated in accordance with Rule
     457(h)(1) under the Securities Act of 1933, as amended, solely for the
     purpose of calculating the registration fee; the price used is the closing
     price of the Common Stock of $1.93 on October 20, 2004, as reported by
     the Nasdaq SmallCap Market.
PART I

              INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS

     In accordance with the Note to Part I of the Registration Statement on Form
S-8, the document(s) containing the information specified in Part I of the
Registration Statement on Form S-8 is not being filed with the Commission either
as part of this Registration Statement or as prospectuses or prospectus
supplements pursuant to Rule 424 under the Securities Act of 1933.
PART II

               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

Item 3. Incorporation of Documents by Reference.

     The following documents filed by the Company with the SEC pursuant to the
Securities Exchange Act of 1934 (the "Exchange Act") are incorporated by
reference:

     (a) the Company's Annual Report on Form 10-KSB for the year ended December
31, 2003, filed on March 30, 2004;

     (b) the Company's definitive Proxy Statement dated April 29, 2004
distributed in connection with the Company's Annual Meeting of Shareholders held
on June 15, 2004;

     (c) the Company's Quarterly Report on Form 10-QSB for the quarter ended
March 31, 2004, filed on May 17, 2004;

     (d) the Company's Quarterly Report on Form 10-QSB for the quarter ended
June 30, 2004, filed on August 12, 2004;

     (e) the Company's Current Report on Form 8-K dated September 30, 2004; and

     (f) the description of the Company's common stock contained under the
caption "Description of Our Capital Stock and Other Securities - Units" in the
Prospectus included in the Company's Registration Statement on Form SB-2 (No.
333-101661), declared effective on May 15, 2003.

     All documents that the Company files with the SEC pursuant to Sections
13(a), 13(c), 14 or 15(d) of the Securities Exchange Act of 1934 after the date
hereof and prior to the filing of a post-effective amendment to this
registration statement that indicates that all the common stock offered has been
sold, or which deregisters all common stock then remaining unsold hereunder,
shall be incorporated by reference into this registration statement and to be a
part hereof (and of the prospectus(es)) from the date of filing of such
documents. Any statement contained in the prospectus(es) will be deemed to be
modified or superseded for purposes of this registration statement to the extent
that a statement contained in any subsequently filed document which also is or
is deemed to be incorporated by reference herein modifies or supersedes such
statement. Any such statement so modified or superseded will not be deemed,
except as so modified or superseded, to constitute a part of this registration
statement.

Item 8. Exhibits.

Exhibit                          Description
  No.
3.1  Amended and Restated Certificate of Incorporation of the Company, as
     amended to June 16, 2004 (incorporated by reference to Exhibit 3(i) to the
     Company's Quarterly Report on Form 10-QSB for the quarter ended June 30,
     2004)

3.2  Amended and Restated By-laws of the Company (incorporated by reference to
     Exhibit 3.2 to Amendment No. 1 to the Company's Registration Statement on
     Form SB-2 (Registration No. 333-39470))

                                      II-1
4.1  Warrant Agreement, dated as of January 5, 2001, by and between Delcath
     Systems, Inc. and Euroland Marketing Solutions, Ltd. (incorporated by
     reference to Exhibit 4.5 to the Company's Annual Report on Form 10-KSB for
     the year ended December 31, 2000 (Commission File No. 001-16133))

4.2  Warrant No. W-2 to purchase up to 150,000 units granted to Euroland
     Marketing Services, Ltd. (incorporated by reference to Exhibit 4.6 to the
     Company's Annual Report on Form 10-KSB for the year ended December 31, 2000
     (Commission File No. 001-16133))

4.3  Rights Agreement, dated October 30, 2001, by and between Delcath Systems,
     Inc. and American Stock Transfer & Trust Company, as Rights Agent
     (incorporated by reference to Exhibit 4.7 to the Company's Form 8-A dated
     November 12, 2001 (Commission File No. 001-16133))

4.4  Form of Warrant Agreement by and between Delcath Systems, Inc. and Whale
     Securities Co., L.P. (incorporated by reference to Exhibit 4.2 to Amendment
     No. 5 to the Company's Registration Statement on Form SB-2 (Registration
     No. 333-39470))

4.5  Form of Warrant Agent Agreement by and among Delcath Systems, Inc., Whale
     Securities Co., L.P., and American Stock Transfer & Trust Company, as
     warrant agent (incorporated by reference to Exhibit 4.3 to Amendment No. 5
     to the Company's Registration Statement on Form SB-2 (Registration No.
     333-39470))

4.6  Form of Underwriter's Unit Warrant Agreement between Delcath Systems, Inc.
     and Roan/Meyers Associates L.P. (incorporated by reference to Exhibit 4.1
     to Amendment No. 1 to the Company's Registration Statement on Form SB-2
     (Registration No. 333-101661)).

4.7  Specimen 2003 Warrant (incorporated by reference to Exhibit 4.2 to
     Amendment No. 1 to the Company's Registration Statement on Form SB-2
     (Registration No. 333-101661))

4.8  Form of Warrant Agent Agreement by and between Delcath Systems, Inc. and
     American Stock Transfer & Trust Company, as warrant agent, with respect to
     the 2003 Warrants (incorporated by reference to Exhibit 4.8 to Amendment
     No. 3 to the Company's Registration Statement on Form SB-2 (Registration
     No. 333-101661))

5.1  Opinion of Murtha Cullina LLP

23.1 Consent of Eisner LLP

23.2 Consent of Murtha Cullina LLP (included in Exhibit 5.1)

24   Power of attorney of certain officers and directors of the Company

99.1 2000 Stock Option Plan (incorporated by reference to Exhibit 10.3 to the
     Company's Registration Statement on Form SB-2 (Registration No. 333-39470))

                                      II-2
99.2 2001 Stock Option Plan (incorporated by reference to Exhibit 10.12 to
     Amendment No. 1 to the Company's Annual Report on Form 10-KSB for the year
     ended December 31, 2001 (Commission File No. 001-16133))

99.3 2004 Stock Incentive Plan (incorporated by reference to Exhibit B to the
     Company's definitive Proxy Statement dated April 29, 2004 (Commission File
     No. 001-16133))

Item 9. Undertakings.

     (a) The Company hereby undertakes:

     (1) To file, during any period in which offers or sales are being made, a
post-effective amendment to this Registration Statement:

     (i) to include any prospectus required by Section 10(a)(3) of the
Securities Act;

     (ii) to reflect in the prospectus any facts or events arising after the
effective date of this Registration Statement (or the most recent post-effective
amendment hereof) which, individually or in the aggregate, represent a
fundamental change in the information set forth in this Registration Statement;

     (iii) to include any material information with respect to the plan of
distribution not previously disclosed in this Registration Statement or any
material change to such information in this Registration Statement;

provided, however, that the undertakings set forth in paragraphs (i) and (ii)
above do not apply if the information required to be included in a
post-effective amendment by those paragraphs is contained in periodic reports
filed with or furnished to the SEC by the Company pursuant to Section 13 or
Section 15(d) of the Exchange Act that are incorporated by reference in this
Registration Statement.

     (2) That, for the purpose of determining any liability under the Securities
Act, each such post-effective amendment shall be deemed to be a new registration
statement relating to the securities offered therein, and the offering of such
securities at that time shall be deemed to be the initial bona fide offering
thereof.

     (3) To remove from registration by means of a post-effective amendment any
of the securities being registered hereby which remain unsold at the termination
of the offering.

     (b) The Company hereby undertakes that, for purposes of determining any
liability under the Securities Act, each filing of the Company's annual report
pursuant to Section 13(a) or 15(d) of the Exchange Act (and, where applicable,
each filing of an employee benefit plan's annual report pursuant to Section
15(d) of the Exchange Act) that is incorporated by reference in the Registration
Statement shall be deemed to be a new registration statement relating to the
securities offered therein, and the offering of such securities at that time
shall be deemed to be the initial bona fide offering thereof.

     (h) Insofar as indemnification for liabilities arising under the Securities
Act may be permitted to directors, officers and controlling persons of the
Company pursuant to the foregoing provisions, or otherwise, the Company has been
advised that in the opinion of the SEC such indemnification is against public
policy as expressed in the Securities Act and is, therefore, unenforceable. In
the event that a claim for indemnification against such liabilities (other than
the payment by the Company of expenses incurred or paid by a director or officer
or controlling person of the Company in the successful defense of any action,
suit or proceeding) is asserted by such director, officer or controlling person
in connection with the securities being

                                      II-3
registered, the Company will, unless in the opinion of its counsel the matter
has been settled by controlling precedent, submit to a court of appropriate
jurisdiction the question of whether such indemnification by it is against
public policy as expressed in the Securities Act and will be governed by the
final adjudication of such issue.

                                      II-4
SIGNATURES

     Pursuant to the requirements of the Securities Act of 1933, as amended, the
registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of Stamford, State of Connecticut on October 21, 2004.

                                       Delcath Systems, Inc.

                                       By:         /s/ M. S Koly
                                           ----------------------------------
                                       Name:    M. S Koly
                                       Title:   President and Chief Executive
                                                Officer

     Pursuant to the requirements of the Securities Act of 1933, this
registration statement has been signed by the following persons in the
capacities and on the date indicated.

Name                    Title
----                    -----
M. S. Koly           President and Chief Executive)
                     Officer and Director         )
                     (Principal Executive Officer )
                                                  )
Paul M. Feinstein    Chief Financial Officer      )
                     (Principal Financial Officer))   By: /s/ M. S. Koly
                                                  )       --------------
Samuel Herschkowitz  Chairman and Director        )       Attorney-in-Fact
                                                  )
Mark A.Corigliano    Director                     )   Dated: October 21, 2004
                                                  )
Daniel Isdaner       Director                     )
                                                  )
Victor Nevins        Director                     )

                                      II-5
EXHIBIT INDEX

Exhibit                         Description
 No.
3.1  Amended and Restated Certificate of Incorporation of the Company, as
     amended to June 16, 2004 (incorporated by reference to Exhibit 3(i) to the
     Company's Quarterly Report on Form 10-QSB for the quarter ended June 30,
     2004)

3.2  Amended and Restated By-laws of the Company (incorporated by reference to
     Exhibit 3.2 to Amendment No. 1 to the Company's Registration Statement on
     Form SB-2 (Registration No. 333-39470))

4.1  Warrant Agreement, dated as of January 5, 2001, by and between Delcath
     Systems, Inc. and Euroland Marketing Solutions, Ltd. (incorporated by
     reference to Exhibit 4.5 to the Company's Annual Report on Form 10-KSB for
     the year ended December 31, 2000 (Commission File No. 001-16133))

4.2  Warrant No. W-2 to purchase up to 150,000 units granted to Euroland
     Marketing Services, Ltd. (incorporated by reference to Exhibit 4.6 to the
     Company's Annual Report on Form 10-KSB for the year ended December 31, 2000
     (Commission File No. 001-16133))

4.3  Rights Agreement, dated October 30, 2001, by and between Delcath Systems,
     Inc. and American Stock Transfer & Trust Company, as Rights Agent
     (incorporated by reference to Exhibit 4.7 to the Company's Form 8-A dated
     November 12, 2001 (Commission File No. 001-16133))

4.4  Form of Warrant Agreement by and between Delcath Systems, Inc. and Whale
     Securities Co., L.P. (incorporated by reference to Exhibit 4.2 to Amendment
     No. 5 to the Company's Registration Statement on Form SB-2 (Registration
     No. 333-39470))

4.5  Form of Warrant Agent Agreement by and among Delcath Systems, Inc., Whale
     Securities Co., L.P., and American Stock Transfer & Trust Company, as
     warrant agent (incorporated by reference to Exhibit 4.3 to Amendment No. 5
     to the Company's Registration Statement on Form SB-2 (Registration No.
     333-39470))

4.6  Form of Underwriter's Unit Warrant Agreement between Delcath Systems, Inc.
     and Roan/Meyers Associates L.P. (incorporated by reference to Exhibit 4.1
     to Amendment No. 1 to the Company's Registration Statement on Form SB-2
     (Registration No. 333-101661)).

4.7  Specimen 2003 Warrant (incorporated by reference to Exhibit 4.2 to
     Amendment No. 1 to the Company's Registration Statement on Form SB-2
     (Registration No. 333-101661))

4.8  Form of Warrant Agent Agreement by and between Delcath Systems, Inc. and
     American Stock Transfer & Trust Company, as warrant agent, with respect to
     the 2003 Warrants (incorporated by reference to Exhibit 4.8 to Amendment
     No. 3 to the Company's Registration Statement on Form SB-2 (Registration
     No. 333-101661))

5.1  Opinion of Murtha Cullina LLP
23.1 Consent of Eisner LLP

23.2 Consent of Murtha Cullina LLP (included in Exhibit 5.1)

24   Power of attorney of certain officers and directors of the Company

99.1 2000 Stock Option Plan (incorporated by reference to Exhibit 10.3 to the
     Company's Registration Statement on Form SB-2 (Registration No. 333-39470))

99.2 2001 Stock Option Plan (incorporated by reference to Exhibit 10.12 to
     Amendment No. 1 to the Company's Annual Report on Form 10-KSB for the year
     ended December 31, 2001 (Commission File No. 001-16133))

99.3 2004 Stock Incentive Plan (incorporated by reference to Exhibit B to the
     Company's definitive Proxy Statement dated April 29, 2004 (Commission File
     No. 001-16133))