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			alim s-8
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			<font style="display: inline;font-weight:bold;">As filed with the Securities and Exchange Commission on </font><a name="Cover"></a><font style="display: inline;font-weight:bold;">Octo</font><font style="display: inline;font-weight:bold;">ber </font><font style="display: inline;font-weight:bold;">29</font><font style="display: inline;font-weight:bold;">, 2021</font>
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			<font style="display: inline;font-weight:bold;">Registration No. 333-</font>
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			<font style="display: inline;font-weight:bold;">UNITED STATES</font><br /><font style="display: inline;font-weight:bold;">SECURITIES AND EXCHANGE COMMISSION</font>
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			<font style="display: inline;font-weight:bold;">WASHINGTON, D.C. 20549</font>
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			<font style="display: inline;">___________________</font>
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			<font style="display: inline;">&#xFEFF;</font>
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			<font style="display: inline;font-weight:bold;">FORM S</font><font style="display: inline;">&#8209;</font><font style="display: inline;font-weight:bold;">8</font>
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			<font style="display: inline;font-weight:bold;">REGISTRATION STATEMENT</font>
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			<font style="display: inline;font-weight:bold;">Under</font>
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			<font style="display: inline;font-weight:bold;">The Securities Act of 1933</font>
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			<font style="display: inline;">___________________</font>
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			<font style="display: inline;font-size:8pt;">&#xFEFF;</font>
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			<font style="display: inline;font-weight:bold;font-size:14pt;">ALIMERA SCIENCES, INC.</font>
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		<p style="margin:0pt 0pt 7pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">(Exact name of registrant as specified in its charter)</font>
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						<font style="display: inline;font-weight:bold;">Delaware</font></p>
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						<font style="display: inline;">(State or other jurisdiction of incorporation or organization)</font></p>
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						&nbsp;</p>
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						<font style="display: inline;font-weight:bold;">20-0028718</font></p>
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						<font style="display: inline;">(IRS Employer</font></p>
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						<font style="display: inline;">Identification No.)</font></p>
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			<font style="display: inline;">&#xFEFF;</font>
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			<font style="display: inline;font-weight:bold;background-color: #FFFFFF;">6120 Windward Parkway, Suite 290</font>
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			<font style="display: inline;font-weight:bold;background-color: #FFFFFF;">Alpharetta, GA 30005</font>
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			<font style="display: inline;">(Address of principal executive offices) (Zip Code)</font>
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			<font style="display: inline;">___________________</font>
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			<font style="display: inline;font-size:8pt;">&#xFEFF;</font>
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		<p style="margin:0pt;line-height:108.33%;text-align:center;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;">ALIMERA SCIENCES, INC. 201</font><font style="display: inline;font-weight:bold;">9</font><font style="display: inline;font-weight:bold;">&nbsp;</font><font style="display: inline;font-weight:bold;">OMNIBUS</font><font style="display: inline;font-weight:bold;"> INCENTIVE PLAN</font>
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			<font style="display: inline;font-weight:bold;">ALIMERA SCIENCES, INC. 2010 EMPLOYEE STOCK PURCHASE PLAN</font>
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			<font style="display: inline;">(Full title of the </font><font style="display: inline;">p</font><font style="display: inline;">lan)</font>
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			<font style="display: inline;">___________________</font>
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			<font style="display: inline;font-weight:bold;font-size:8pt;">&#xFEFF;</font>
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			<font style="display: inline;font-weight:bold;background-color: #FFFFFF;">Richard S. Eiswirth, Jr.</font>
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			<font style="display: inline;font-weight:bold;background-color: #FFFFFF;">President and Chief Executive Officer</font>
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			<font style="display: inline;font-weight:bold;background-color: #FFFFFF;">6120 Windward Parkway, Suite 290</font>
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		<p style="margin:0pt;line-height:108.33%;text-align:center;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;background-color: #FFFFFF;">Alpharetta, GA 30005</font>
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			<font style="display: inline;">(Name and address of agent for service)</font>
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		<p style="margin:0pt;line-height:108.33%;text-align:center;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;">(678)&nbsp;990-5740</font>
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			<font style="display: inline;">(Telephone number, including area code, of agent for service)</font>
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		<p style="margin:0pt;line-height:108.33%;text-align:center;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">&#xFEFF;</font>
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			<font style="display: inline;font-weight:bold;font-style:italic;">Copies to:</font>
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		<p style="margin:0pt 0pt 7pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-style:italic;">&#xFEFF;</font>
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						<font style="display: inline;font-weight:bold;">Charles D. Vaughn</font></p>
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					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;font-weight:bold;">Christopher S. Visick</font></p>
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					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;font-weight:bold;">Nelson Mullins Riley &amp; Scarborough LLP</font></p>
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					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;font-weight:bold;">Vice President and General Counsel</font></p>
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						<font style="display: inline;font-weight:bold;">Atlantic Station, Suite 1700</font></p>
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						<font style="display: inline;font-weight:bold;">6120 Windward Parkway, Suite 290</font></p>
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						<font style="display: inline;font-weight:bold;">201 17</font><font style="display: inline;font-weight:bold;font-size:5pt;vertical-align:super;line-height:100%">th</font><font style="display: inline;font-weight:bold;"> Street NW</font></p>
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					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;font-weight:bold;">Alpharetta, GA 30005</font></p>
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						<font style="display: inline;font-weight:bold;">Atlanta, GA 30363</font></p>
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					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;font-weight:bold;">(678) 990-5740</font></p>
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					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;font-weight:bold;">(404) 322-6000</font></p>
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					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
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			<font style="display: inline;">___________________</font>
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		<p style="margin:0pt;line-height:120%;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 8pt">
			<font style="display: inline;font-size:8pt;">&#xFEFF;</font>
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		<p style="margin:0pt 0pt 7pt;line-height:120%;font-family:Times New Roman;font-size: 9pt">
			<font style="display: inline;font-size:9pt;">Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer a smaller reporting company or an emerging growth company. See the definitions of &#x201C;large accelerated filer,&#x201D; &#x201C;accelerated filer,&#x201D; &#x201C;smaller reporting company,&#x201D; and &#x201C;emerging growth company&#x201D; in Rule 12b-2 of the Exchange Act.</font>
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					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;font-size:9pt;">Large accelerated filer </font><font style="display: inline;">&#x2610;</font></p>
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					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;font-size:9pt;">Accelerated filer </font><font style="display: inline;">&#x2610;</font></p>
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						<font style="display: inline;font-size:9pt;">Non-accelerated filer</font><font style="display: inline;font-size:9pt;">&nbsp;</font><font style="display: inline;">&#x2612;</font><font style="display: inline;font-size:9pt;">&nbsp;</font></p>
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					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;font-size:9pt;">Smaller reporting company </font><font style="display: inline;">&#x2612;</font></p>
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					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">&#xFEFF;</font></p>
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					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;font-size:9pt;">Emerging Growth Company </font><font style="display: inline;">&#x2610;</font></p>
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					<p style="margin:0pt;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;font-size:9pt;">If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act</font></p>
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					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">&#x2610;</font></p>
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			<font style="display: inline;">&#xFEFF;</font>
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			<font style="display: inline;">II-</font><font style="display: inline;"></font><font style="display: inline;">1</font><font style="display: inline;"></font>

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</div><hr size="3" style="color:#999999" width="100%" align="center"></hr><p style="page-break-after:always">&nbsp;</p><div style="width:100%">

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			&nbsp;

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		<p style="margin:0pt;line-height:108.33%;text-align:center;font-family:Times New Roman;;font-size: 10pt"><font style="display: inline;font-weight:bold;">CALCULATION OF REGISTRATION FEE</font>
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						<font style="display: inline;font-weight:bold;font-size:8pt;">&#xFEFF;</font></p>
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						<font style="display: inline;font-weight:bold;font-size:8pt;"> (1)</font></p>
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						&nbsp;</p>
				</td>
				<td valign="bottom" style="width:01.06%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;padding:0pt 0pt 0pt 0pt;height:1.00pt">
					<p style="margin:0pt;font-family:Times New Roman;height:1.00pt;overflow:hidden;font-size:0pt;">
						&nbsp;</p>
				</td>
				<td valign="bottom" style="width:17.10%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;padding:0pt 3.6pt 0pt 3.6pt;height:1.00pt">
					<p style="margin:0pt;font-family:Times New Roman;height:1.00pt;overflow:hidden;font-size:0pt;">
						&nbsp;</p>
				</td>
				<td valign="bottom" style="width:01.06%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;padding:0pt 0pt 0pt 0pt;height:1.00pt">
					<p style="margin:0pt;font-family:Times New Roman;height:1.00pt;overflow:hidden;font-size:0pt;">
						&nbsp;</p>
				</td>
				<td valign="bottom" style="width:17.10%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;padding:0pt 3.6pt 0pt 3.6pt;height:1.00pt">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;height:1.00pt;overflow:hidden;font-size:0pt;">
						&nbsp;</p>
				</td>
			</tr>
			<tr>
				<td valign="bottom" style="width:33.12%;border-bottom:1pt solid #000000 ;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 8pt">
						<font style="display: inline;font-weight:bold;font-size:8pt;">&#xFEFF;</font></p>
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 8pt">
						<font style="display: inline;font-weight:bold;font-size:8pt;">Title of Securities to be Registered</font></p>
				</td>
				<td valign="bottom" style="width:01.06%;padding:0pt 0pt 0pt 0pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
				<td valign="bottom" style="width:14.32%;border-bottom:1pt solid #000000 ;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 8pt">
						<font style="display: inline;font-weight:bold;font-size:8pt;">Amount to be Registered</font><font style="display: inline;font-weight:bold;font-size:8pt;"> (1)</font></p>
				</td>
				<td valign="bottom" style="width:00.86%;padding:0pt 0pt 0pt 0pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
				<td valign="bottom" style="width:14.32%;border-bottom:1pt solid #000000 ;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 8pt">
						<font style="display: inline;font-weight:bold;font-size:8pt;">Proposed Maximum Offering Price per Share</font><font style="display: inline;font-weight:bold;font-size:8pt;"> (2)</font></p>
				</td>
				<td valign="bottom" style="width:01.06%;padding:0pt 0pt 0pt 0pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
				<td valign="bottom" style="width:17.10%;border-bottom:1pt solid #000000 ;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 8pt">
						<font style="display: inline;font-weight:bold;font-size:8pt;">Proposed Maximum Aggregate Offering Price</font><font style="display: inline;font-weight:bold;font-size:8pt;"> (2)</font></p>
				</td>
				<td valign="bottom" style="width:01.06%;padding:0pt 0pt 0pt 0pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
				<td valign="bottom" style="width:17.10%;border-bottom:1pt solid #000000 ;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 8pt">
						<font style="display: inline;font-weight:bold;font-size:8pt;">Amount of Registration Fee</font></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:33.12%;background-color: #CCEEFF;padding:0pt 2.4pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;font-size:9pt;">Common Stock, </font><font style="display: inline;font-size:9pt;">$0.01</font><font style="display: inline;font-size:9pt;"> par value &#x2013;</font></p>
					<p style="margin:0pt;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;font-size:9pt;">2019 Omnibus Incentive Plan</font></p>
				</td>
				<td valign="top" style="width:01.06%;background-color: #CCEEFF;padding:0pt 0pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
				<td valign="top" style="width:14.32%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:right;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;font-size:9pt;">1,000,000 (3)</font></p>
				</td>
				<td valign="top" style="width:00.86%;background-color: #CCEEFF;padding:0pt 0pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
				<td valign="top" style="width:14.32%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;font-size:9pt;">$4.52</font></p>
				</td>
				<td valign="top" style="width:01.06%;background-color: #CCEEFF;padding:0pt 0pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
				<td valign="top" style="width:17.10%;background-color: #CCEEFF;font-family:Times New Roman;font-size:9pt;text-align:right;" nowrap="nowrap">$4,520,000.00&nbsp;
				</td>
				<td valign="top" style="width:01.06%;background-color: #CCEEFF;padding:0pt 0pt 0pt 0pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
				<td valign="top" style="width:17.10%;background-color: #CCEEFF;font-family:Times New Roman;font-size:9pt;text-align:right;" nowrap="nowrap">$419.01&nbsp;
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:33.12%;padding:0pt 2.4pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;font-size:9pt;">Common Stock, </font><font style="display: inline;font-size:9pt;">$0.01</font><font style="display: inline;font-size:9pt;"> par value &#x2013;</font></p>
					<p style="margin:0pt;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;font-size:9pt;">201</font><font style="display: inline;font-size:9pt;">0</font><font style="display: inline;font-size:9pt;">&nbsp;</font><font style="display: inline;font-size:9pt;">Employee Stock Purchase Plan</font></p>
				</td>
				<td valign="top" style="width:01.06%;padding:0pt 0pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
				<td valign="top" style="width:14.32%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:right;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;font-size:9pt;">13,812 (4) </font></p>
				</td>
				<td valign="top" style="width:00.86%;padding:0pt 0pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
				<td valign="top" style="width:14.32%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;font-size:9pt;">$4.52</font></p>
				</td>
				<td valign="top" style="width:01.06%;padding:0pt 0pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
				<td valign="top" style="width:17.10%;font-family:Times New Roman;font-size:9pt;text-align:right;" nowrap="nowrap">$62,430.24&nbsp;
				</td>
				<td valign="top" style="width:01.06%;padding:0pt 0pt 0pt 0pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
				<td valign="top" style="width:17.10%;font-family:Times New Roman;font-size:9pt;text-align:right;" nowrap="nowrap">$5.79&nbsp;
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:33.12%;background-color: #CCEEFF;padding:0pt 2.4pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;font-weight:bold;font-size:9pt;">Total</font></p>
				</td>
				<td valign="top" style="width:01.06%;background-color: #CCEEFF;padding:0pt 0pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
				<td valign="top" style="width:14.32%;background-color: #CCEEFF;font-family:Times New Roman;font-size:9pt;text-align:right;" nowrap="nowrap">1,013,812&nbsp;
				</td>
				<td valign="top" style="width:00.86%;background-color: #CCEEFF;padding:0pt 0pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
				<td valign="top" style="width:14.32%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;font-size:9pt;">N/A</font></p>
				</td>
				<td valign="top" style="width:01.06%;background-color: #CCEEFF;padding:0pt 0pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
				<td valign="top" style="width:17.10%;background-color: #CCEEFF;font-family:Times New Roman;font-size:9pt;text-align:right;" nowrap="nowrap">$4,582,430.24&nbsp;
				</td>
				<td valign="top" style="width:01.06%;background-color: #CCEEFF;padding:0pt 0pt 0pt 0pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
				<td valign="top" style="width:17.10%;background-color: #CCEEFF;font-family:Times New Roman;font-size:9pt;text-align:right;" nowrap="nowrap">$424.80&nbsp;
				</td>
			</tr>
		</table></div>
		<p style="margin:2pt 0pt 3pt;line-height:105.83%;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">_______________________________</font>
		</p>
		<div style="width:100%"><table style="width:100%; table-layout: fixed;" cellpadding="0" cellspacing="0"><tr><td style="width:0pt;"><p style="width:0pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 19.00pt;">
			<p style="line-height:106.25%;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 9pt;margin:0pt;">
				<font style="margin:0pt;line-height:106.25%;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size:9pt;;"> (1)</font>
			</p>
		</td><td style="width:17pt;"><p style="width:17pt;width:17pt;font-size:0pt;"></p></td><td align="left" valign="top">
			<p style="line-height:106.25%;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 9pt;margin:0pt;">
			<font style="display: inline;font-size:9pt;color:#000000;">The shares </font><font style="display: inline;font-size:9pt;color:#000000;">registered hereunder </font><font style="display: inline;font-size:9pt;color:#000000;">include:</font><font style="display: inline;font-size:9pt;color:#000000;">&nbsp;</font><font style="display: inline;font-size:9pt;color:#000000;">(a) an additional </font><font style="display: inline;font-size:9pt;color:#000000;">1,000</font><font style="display: inline;font-size:9pt;color:#000000;">,000 shares of the Common Stock, $0.01 par value (&#x201C;Common Stock&#x201D;), of Alimera Sciences, Inc. </font><font style="display: inline;font-size:9pt;color:#000000;">(the &#x201C;Company&#x201D; or the &#x201C;registrant&#x201D;)</font><font style="display: inline;font-size:9pt;color:#000000;">&nbsp;</font><font style="display: inline;font-size:9pt;color:#000000;">reserved for issuance pursuant to the Alimera Sciences, Inc. 201</font><font style="display: inline;font-size:9pt;color:#000000;">9</font><font style="display: inline;font-size:9pt;color:#000000;">&nbsp;</font><font style="display: inline;font-size:9pt;color:#000000;">Omnibus</font><font style="display: inline;font-size:9pt;color:#000000;"> Incentive Plan</font><font style="display: inline;font-size:9pt;color:#000000;">&nbsp;</font><font style="display: inline;font-size:9pt;color:#000000;">(the &#x201C;2019 Plan&#x201D;)</font><font style="display: inline;font-size:9pt;color:#000000;">; and (b) </font><font style="display: inline;font-size:9pt;color:#000000;">13,812</font><font style="display: inline;font-size:9pt;color:#000000;"> shares of Common Stock </font><font style="display: inline;font-size:9pt;color:#000000;">reserved for issuance pursuant to the Alimera Sciences, Inc. 2010 Employee Stock Purchase Plan (the &#x201C;2010 ESPP&#x201D;). </font><font style="display: inline;font-size:9pt;color:#000000;">This Registration Statement </font><font style="display: inline;font-size:9pt;color:#000000;">also cover</font><font style="display: inline;font-size:9pt;color:#000000;">s</font><font style="display: inline;font-size:9pt;color:#000000;"> any additional shares of Common Stock that become issuable under </font><font style="display: inline;font-size:9pt;color:#000000;">the 2019</font><font style="display: inline;font-size:9pt;color:#000000;">&nbsp;</font><font style="display: inline;font-size:9pt;color:#000000;">Plan</font><font style="display: inline;font-size:9pt;color:#000000;">&nbsp;</font><font style="display: inline;font-size:9pt;color:#000000;">or the 2010 ESPP </font><font style="display: inline;font-size:9pt;color:#000000;">by reason of any stock dividend, stock split, recapitalization or other similar transaction effected without the receipt of consideration </font><font style="display: inline;font-size:9pt;color:#000000;">that</font><font style="display: inline;font-size:9pt;color:#000000;"> results in an increase in the number of the outstanding shares of Common Stock.</font></p></td></tr></table></div>
		<p style="margin:0pt 0pt 0pt 36pt;line-height:106.25%;text-indent: -36pt;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 9pt">
			<font style="display: inline;font-size:9pt;color:#000000;">&#xFEFF;</font>
		</p>
		<div style="width:100%"><table style="width:100%; table-layout: fixed;" cellpadding="0" cellspacing="0"><tr><td style="width:0pt;"><p style="width:0pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 19.00pt;">
			<p style="line-height:106.25%;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 9pt;margin:0pt;">
				<font style="margin:0pt;line-height:106.25%;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size:9pt;;"> (2)</font>
			</p>
		</td><td style="width:17pt;"><p style="width:17pt;width:17pt;font-size:0pt;"></p></td><td align="left" valign="top">
			<p style="line-height:106.25%;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 9pt;margin:0pt;">
			<font style="display: inline;font-size:9pt;color:#000000;">Estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rule 457(c) and </font><font style="display: inline;font-size:9pt;color:#000000;">Rule 457</font><font style="display: inline;font-size:9pt;color:#000000;">(h)(1) under the </font><font style="display: inline;font-size:9pt;color:#000000;">Securities Act of 1933, as amended (the &#x201C;Securities Act&#x201D;)</font><font style="display: inline;font-size:9pt;color:#000000;">. The offering price per share and aggregate offering price for the shares of Common Stock are based upon the average of the high and low prices of the Common Stock as reported on The N</font><font style="display: inline;font-size:9pt;color:#000000;">asdaq</font><font style="display: inline;font-size:9pt;color:#000000;"> Global Market on </font><font style="display: inline;font-size:9pt;color:#000000;">October</font><font style="display: inline;font-size:9pt;color:#000000;">&nbsp;</font><font style="display: inline;font-size:9pt;color:#000000;">26</font><font style="display: inline;font-size:9pt;color:#000000;">, 2021.</font></p></td></tr></table></div>
		<p style="margin:0pt 0pt 0pt 36pt;line-height:106.25%;text-indent: -36pt;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 9pt">
			<font style="display: inline;font-size:9pt;color:#000000;">&#xFEFF;</font>
		</p>
		<div style="width:100%"><table style="width:100%; table-layout: fixed;" cellpadding="0" cellspacing="0"><tr><td style="width:0pt;"><p style="width:0pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 19.00pt;">
			<p style="line-height:106.25%;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 9pt;margin:0pt;">
				<font style="margin:0pt;line-height:106.25%;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size:9pt;;"> (3)</font>
			</p>
		</td><td style="width:17pt;"><p style="width:17pt;width:17pt;font-size:0pt;"></p></td><td align="left" valign="top">
			<p style="line-height:106.25%;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 9pt;margin:0pt;">
			<font style="display: inline;font-size:9pt;color:#000000;">Represents </font><font style="display: inline;font-size:9pt;color:#000000;">1,000,000 </font><font style="display: inline;font-size:9pt;color:#000000;">shares of Common Stock that were added to the shares of Common Stock authorized for issuance under the 20</font><font style="display: inline;font-size:9pt;color:#000000;">19</font><font style="display: inline;font-size:9pt;color:#000000;">&nbsp;</font><font style="display: inline;font-size:9pt;color:#000000;">Plan</font><font style="display: inline;font-size:9pt;color:#000000;">&nbsp;</font><font style="display: inline;font-size:9pt;color:#000000;">under an</font><font style="display: inline;font-size:9pt;color:#000000;"> amend</font><font style="display: inline;font-size:9pt;color:#000000;">ment approved by the Company&#x2019;s</font><font style="display: inline;font-size:9pt;color:#000000;"> stockholder</font><font style="display: inline;font-size:9pt;color:#000000;">s &nbsp;</font><font style="display: inline;font-size:9pt;color:#000000;">on June 15, 2021</font><font style="display: inline;font-size:9pt;color:#000000;">.</font></p></td></tr></table></div>
		<p style="margin:0pt 0pt 0pt 36pt;font-family:Times New Roman;font-size: 9pt">
			<font style="display: inline;font-size:9pt;color:#000000;">&#xFEFF;</font>
		</p>
		<div style="width:100%"><table style="width:100%; table-layout: fixed;" cellpadding="0" cellspacing="0"><tr><td style="width:0pt;"><p style="width:0pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 19.00pt;">
			<p style="line-height:106.25%;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 9pt;margin:0pt;">
				<font style="margin:0pt;line-height:106.25%;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size:9pt;;"> (4)</font>
			</p>
		</td><td style="width:17pt;"><p style="width:17pt;width:17pt;font-size:0pt;"></p></td><td align="left" valign="top">
			<p style="line-height:106.25%;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 9pt;margin:0pt;">
			<font style="display: inline;font-size:9pt;color:#000000;">Represents </font><a name="_Hlk83033779"></a><font style="display: inline;font-size:9pt;color:#000000;">13,812</font><font style="display: inline;font-size:9pt;color:#000000;"> shares of</font><font style="display: inline;font-size:9pt;color:#000000;"> Common Stock that were </font><font style="display: inline;font-size:9pt;color:#000000;">automatically added to the shares of Common Stock authorized for issuance under the 2010 ESPP on January 1, 202</font><font style="display: inline;font-size:9pt;color:#000000;">1</font><font style="display: inline;font-size:9pt;color:#000000;"> pursuant to an &#x201C;evergreen&#x201D; provision contained in the 2010 ESPP</font><font style="display: inline;font-size:9pt;color:#000000;">.</font><font style="display: inline;font-size:9pt;color:#000000;">&nbsp;</font><font style="display: inline;font-size:9pt;color:#000000;">Under that provision, on January 1 of each year from January 1, 2011 through and including January 1, 202</font><font style="display: inline;font-size:9pt;color:#000000;">1</font><font style="display: inline;font-size:9pt;color:#000000;">, the aggregate number of shares of Common Stock available for purchase during the life of the 2010 ESPP automatically increased by the number of shares of Common Stock necessary to cause the number of shares of Common Stock then available for purchase to be restored to 32,961 shares of Common Stock</font><font style="display: inline;font-size:9pt;color:#000000;">&nbsp;</font><a name="_Hlk83030955"></a><font style="display: inline;font-size:9pt;color:#000000;">(which amount takes into account the </font><font style="display: inline;font-size:9pt;color:#000000;">Company</font><font style="display: inline;font-size:9pt;color:#000000;">&#x2019;s one-for-15 reverse stock split that became effective on November 14, 2019)</font><font style="display: inline;font-size:9pt;color:#000000;">.</font></p></td></tr></table></div>
		<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;color:#000000;">&#xFEFF;</font>
		</p>
		<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
			&nbsp;
		</p></div><div style="margin-left:36pt;margin-right:36pt;">
		<p style="margin:0pt 0pt 12pt;line-height:120%;text-indent:36pt;text-align:center;font-family:Times New Roman;font-size: 10pt">

		</p>
		<p><font size="1"> </font></p><div style="width:100%">

		<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">

			<font style="display: inline;">II-</font><font style="display: inline;"></font><font style="display: inline;">2</font><font style="display: inline;"></font>

		</p>

		<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">

			&nbsp;

		</p>

</div><hr size="3" style="color:#999999" width="100%" align="center"></hr><p style="page-break-after:always">&nbsp;</p><div style="width:100%">

		<p style="margin:0pt;line-height:120%;font-family:Times New Roman;font-size: 10pt">

			&nbsp;

		</p>

</div>
		<p style="margin:0pt 0pt 12pt;line-height:120%;text-indent:36pt;text-align:center;font-family:Times New Roman;;font-size: 10pt"><font style="display: inline;font-weight:bold;">INCORPORATION OF DOCUMENTS BY REFERENCE</font>
		</p>
		<p style="margin:0pt 0pt 12pt;line-height:120%;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">This Registration Statement is being filed for the purpose of increasing the number of securities of the same class as other securities for which Registration Statements of the Registrant on Form S-8 relating to the same employee benefit plans are effective.</font><font style="display: inline;">&nbsp;</font><font style="display: inline;">This Registration Statement is being filed for the purpose of increasing the number of securities of the same class as other securities for which Registration Statements of the Registrant on Form S-8 relating to the same employee benefit plan are effective. </font>
		</p>
		<p style="margin:0pt 0pt 12pt;line-height:120%;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">Pursuant to General Instruction E to Form S-8, this Registration Statement hereby incorporates by reference the contents of</font><font style="display: inline;">:</font>
		</p>
		<div style="width:100%"><table style="width:100%; table-layout: fixed;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt;">
			<p style="border-bottom:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
				<font style="margin:0pt;border-bottom:1pt none #D9D9D9;font-family:Times New Roman;font-size:10pt;;"> (a)</font>
			</p>
		</td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top">
			<p style="border-bottom:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
			<font style="display: inline;color:#000000;"> the Registration Statement on Form S-8 relating to the Alimera Sciences, Inc. 201</font><font style="display: inline;color:#000000;">9</font><font style="display: inline;color:#000000;">&nbsp;</font><font style="display: inline;color:#000000;">Omnibus Incentive</font><font style="display: inline;color:#000000;"> Plan filed with the SEC on </font><font style="display: inline;color:#000000;">June 19, 2019</font><font style="display: inline;color:#000000;"> (File No. 333-</font><font style="display: inline;color:#000000;">232206</font><font style="display: inline;color:#000000;">)</font><font style="display: inline;color:#000000;">; and </font></p></td></tr></table></div>
		<p style="margin:0pt 0pt 0pt 54pt;border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;color:#000000;">&#xFEFF;</font>
		</p>
		<div style="width:100%"><table style="width:100%; table-layout: fixed;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt;">
			<p style="border-top:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
				<font style="margin:0pt;border-top:1pt none #D9D9D9;font-family:Times New Roman;font-size:10pt;;"> (b)</font>
			</p>
		</td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top">
			<p style="border-top:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
			<font style="display: inline;color:#000000;">the Registration Statements on Form S-8 relating to the Alimera Sciences, Inc. 2010 Employee Stock Purchase Plan filed with the SEC </font><a name="_Hlk83051927"></a><font style="display: inline;color:#000000;">on May 14, 2010 (File No. 333-166822), March 25, 2011 (File No. 333-173095), April 4, 2012 (File No. 333-180567), March 28, 2013 (File No. 333-187600), March 7, 2014 (File No. 333-194381), January 20, 2015 (File No. 333-201606), January 19, 2016 (File No. 333-209035), January 6, 2017 (File No. 333-215451), January 11, 2018, as amended by Post-Effective Amendment No. 1 on January 12, 2018 (File No. 333-222508), January 16, 2019 (File No. 333-229280), </font><font style="display: inline;color:#000000;">and November 2, 202</font><font style="display: inline;color:#000000;">0</font><font style="display: inline;color:#000000;">&nbsp;</font><font style="display: inline;color:#000000;">(File No. 333-2</font><font style="display: inline;color:#000000;">49811</font><font style="display: inline;color:#000000;">)</font><font style="display: inline;color:#000000;">, &nbsp;</font><font style="display: inline;color:#000000;">in each case except for Item 8, Exhibits, with respect to which the Exhibit Index below is incorporated herein by reference.</font></p></td></tr></table></div>
		<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">

		</p>
		<p><font size="1"> </font></p><div style="width:100%">

		<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 9pt">

			<font style="display: inline;font-size:9pt;">II</font><font style="display: inline;font-size:9pt;">&#8209;4</font>

		</p>

</div><hr size="3" style="color:#999999" width="100%" align="center"></hr><p style="page-break-after:always">&nbsp;</p><div style="width:100%">

		<p style="margin:0pt;line-height:120%;font-family:Times New Roman;font-size: 10pt">

			&nbsp;

		</p>

</div>
		<p style="margin:0pt;font-family:Times New Roman;;font-size: 10pt"><font style="display: inline;"></font>
		</p>
		<p style="margin:0pt 0pt 13pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;">E</font><font style="display: inline;font-weight:bold;">XHIBIT INDEX</font>
		</p>
		<div style="width:100%"><table cellpadding="0" cellspacing="0" align="center" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
			<tr>
				<td valign="bottom" style="width:15.18%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">&#xFEFF;</font></p>
				</td>
				<td valign="bottom" style="width:84.82%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
			</tr>
			<tr>
				<td valign="bottom" style="width:15.18%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;text-decoration:underline;">Exhibit Number</font></p>
				</td>
				<td valign="bottom" style="width:84.82%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;text-decoration:underline;">Exhibit</font></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:15.18%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">4.1</font></p>
				</td>
				<td valign="top" style="width:84.82%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<a href="http://www.sec.gov/Archives/edgar/data/1267602/000126760220000029/exhibit31_12311910-k.htm" style="-sec-extract:exhibit"><font style="display: inline;">Restated Certificate of Incorporation of Registrant, as amended on various dates (filed as Exhibit 3.1 to the Registrant&#x2019;s Annual Report on Form 10-K for the year ended December 31, 2020, as filed on March 5, 2021, and incorporated herein by reference)</font></a></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:15.18%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">4.2</font></p>
				</td>
				<td valign="top" style="width:84.82%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<a href="http://www.sec.gov/Archives/edgar/data/1267602/000126760220000029/exhibit32_12311910-k.htm" style="-sec-extract:exhibit"><font style="display: inline;">Amended and Restated Bylaws of the Registrant, as amended (filed as Exhibit 3.2 to the Registrant&#x2019;s Annual Report on Form 10-K for the year ended December 31, 2020, as filed on March 5, 2021, and incorporated herein by reference)</font></a></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:15.18%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">5.1</font></p>
				</td>
				<td valign="top" style="width:84.82%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<a href="alim-20211029xex5_1.htm" style="-sec-extract:exhibit"><font style="display: inline;">Opinion and consent of Nelson Mullins Riley &amp; Scarborough LLP</font></a></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:15.18%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">23.1</font></p>
				</td>
				<td valign="top" style="width:84.82%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<a href="alim-20211029xex23_1.htm" style="-sec-extract:exhibit"><font style="display: inline;">Consent of Grant Thornton LLP, Independent Registered Public Accounting Firm</font></a></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:15.18%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">23.2</font></p>
				</td>
				<td valign="top" style="width:84.82%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<a href="alim-20211029xex5_1.htm" style="-sec-extract:exhibit"><font style="display: inline;">Consent of Nelson Mullins Riley &amp; Scarborough LLP (included in Exhibit 5.1)</font></a></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:15.18%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">24.1</font></p>
				</td>
				<td valign="top" style="width:84.82%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<a href="#Power_of_Attorney"><font style="display: inline;">Power of Attorney. Reference is made to the Power of Attorney following the signature page of this Registration Statement</font></a></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:15.18%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">99.1</font></p>
				</td>
				<td valign="top" style="width:84.82%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<a href="http://www.sec.gov/Archives/edgar/data/1267602/000126760219000083/exhibit1060.htm" style="-sec-extract:exhibit"><font style="display: inline;">Alimera Sciences, Inc. 2019 Omnibus Incentive Plan (incorporated by reference to Exhibit 10.60 to the Company&#x2019;s Current Report on Form 8-K filed on June 18, 2019)</font></a></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:15.18%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">99.2</font></p>
				</td>
				<td valign="top" style="width:84.82%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<a href="http://www.sec.gov/Archives/edgar/data/1267602/000126760219000083/exhibit1061.htm" style="-sec-extract:exhibit"><font style="display: inline;">Form of Stock Option Agreement under the Alimera Sciences, Inc. 2019 Omnibus Incentive Plan (incorporated by reference to Exhibit 10.61 to the Company&#x2019;s Current Report on Form 8-K filed on June 18, 2019)</font></a></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:15.18%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">99.3</font></p>
				</td>
				<td valign="top" style="width:84.82%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<a href="http://www.sec.gov/Archives/edgar/data/1267602/000126760220000083/exhibit105c.htm" style="-sec-extract:exhibit"><font style="display: inline;">Form of Restricted Stock Agreement under the Alimera Sciences, Inc. 2019 Omnibus Incentive Plan (filed as Exhibit 10.5.C to the Registrant&#x2019;s Quarterly Report on Form 10-Q, as filed May 6, 2020, and incorporated herein by reference)</font></a></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:15.18%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">99.4</font></p>
				</td>
				<td valign="top" style="width:84.82%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<a href="http://www.sec.gov/Archives/edgar/data/1267602/000126760220000083/exhibit105d.htm" style="-sec-extract:exhibit"><font style="display: inline;">Form of Restricted Stock Unit Agreement under the Alimera Sciences, Inc. 2019 Omnibus Incentive Plan (filed as Exhibit 10.5.D to the Registrant&#x2019;s Quarterly Report on Form 10-Q, as filed May 6, 2020, and incorporated herein by reference)</font></a></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:15.18%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;height:9.90pt">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">99.5</font></p>
				</td>
				<td valign="top" style="width:84.82%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;height:9.90pt">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<a href="alim-20211029xex99_5.htm" style="-sec-extract:exhibit"><font style="display: inline;">UK Sub-Plan to the Alimera Sciences, Inc. 2019 Omnibus Incentive Plan</font></a></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:15.18%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">99.6</font></p>
				</td>
				<td valign="top" style="width:84.82%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<a href="alim-20211029xex99_6.htm" style="-sec-extract:exhibit"><font style="display: inline;">Form of UK Sub-Plan Stock Option Agreement</font></a></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:15.18%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">99.7</font></p>
				</td>
				<td valign="top" style="width:84.82%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<a href="http://www.sec.gov/Archives/edgar/data/1267602/000095012310032434/g20643a4exv10w10.htm" style="-sec-extract:exhibit"><font style="display: inline;">2010 Employee Stock Purchase Plan (filed as Exhibit 10.10 to Amendment No. 4 to the Registrant&#x2019;s Registration Statement on Form S-1 (SEC File No. 333-162782), as filed on April 6, 2010, and incorporated herein by reference)</font></a></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:15.18%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">99.8</font></p>
				</td>
				<td valign="top" style="width:84.82%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<a href="http://www.sec.gov/Archives/edgar/data/1267602/000126760215000018/exhibit107a.htm" style="-sec-extract:exhibit"><font style="display: inline;">Amendment No. 1 to 2010 Employee Stock Purchase Plan (filed as Exhibit 10.7.A to the Registrant&#x2019;s Annual Report on Form 10-K, as filed March 13, 2015, and incorporated herein by reference)</font></a></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:15.18%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">99.9</font></p>
				</td>
				<td valign="top" style="width:84.82%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<a href="http://www.sec.gov/Archives/edgar/data/1267602/000126760220000116/alim-20201102xex99_3.htm" style="-sec-extract:exhibit"><font style="display: inline;">Amendment No. 2 to 2010 Employee Stock Purchase Plan (filed as Exhibit 99.3 to the Registrant&#x2019;s Registration Statement on Form S-8, as filed November 2, 2020, and incorporated herein by reference)</font></a></p>
				</td>
			</tr>
		</table></div>
		<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">&#xFEFF;</font>
		</p>
		<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">

		</p>
		<p><font size="1"> </font></p><div style="width:100%">

		<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 9pt">

			<font style="display: inline;font-size:9pt;">II</font><font style="display: inline;font-size:9pt;">&#8209;4</font>

		</p>

</div><hr size="3" style="color:#999999" width="100%" align="center"></hr><p style="page-break-after:always">&nbsp;</p><div style="width:100%">

		<p style="margin:0pt;line-height:120%;font-family:Times New Roman;font-size: 10pt">

			&nbsp;

		</p>

</div>
		<p style="margin:0pt;font-family:Times New Roman;;font-size: 10pt"><font style="display: inline;"></font>
		</p>
		<p style="margin:0pt 0pt 15pt;line-height:120%;text-align:center;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;">SIGNATURES</font><a name="Signatures"></a>
		</p>
		<p style="margin:0pt 0pt 19pt;line-height:120%;text-indent:36pt;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">Pursuant to the requirements of the Securities Act of 1933, as amended, the </font><font style="display: inline;">r</font><font style="display: inline;">egistrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Alpharetta, State of Georgia on this </font><font style="display: inline;">29th</font><font style="display: inline;">&nbsp;</font><font style="display: inline;">day of </font><font style="display: inline;">October</font><font style="display: inline;">,</font><font style="display: inline;"> 2021</font><font style="display: inline;">.</font>
		</p>
		<div style="width:100%"><table cellpadding="0" cellspacing="0" align="center" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
			<tr>
				<td valign="bottom" style="width:52.50%;padding:0pt 0pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">&#xFEFF;</font></p>
				</td>
				<td colspan="2" valign="bottom" style="width:47.50%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;font-weight:bold;color:#000000;">ALIMERA SCIENCES, INC.</font></p>
				</td>
			</tr>
			<tr>
				<td valign="bottom" style="width:52.50%;padding:0pt 0pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">&#xFEFF;</font></p>
				</td>
				<td valign="bottom" style="width:03.64%;padding:0pt 0pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
				<td valign="bottom" style="width:43.86%;padding:0pt 0pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
			</tr>
			<tr>
				<td valign="bottom" style="width:52.50%;padding:0pt 0pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">&#xFEFF;</font></p>
				</td>
				<td valign="bottom" style="width:03.64%;padding:0pt 2.4pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;">By:</font></p>
				</td>
				<td valign="bottom" style="width:43.86%;border-bottom:1pt solid #000000 ;padding:0pt 2.4pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;">/s/ Richard S. Eiswirth, Jr.</font></p>
				</td>
			</tr>
			<tr>
				<td valign="bottom" style="width:52.50%;padding:0pt 0pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">&#xFEFF;</font></p>
				</td>
				<td valign="bottom" style="width:03.64%;padding:0pt 0pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
				<td valign="bottom" style="width:43.86%;padding:0pt 2.4pt 0pt 18pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;">Richard S. Eiswirth, Jr.</font></p>
				</td>
			</tr>
			<tr>
				<td valign="bottom" style="width:52.50%;padding:0pt 0pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">&#xFEFF;</font></p>
				</td>
				<td valign="bottom" style="width:03.64%;padding:0pt 0pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
				<td valign="bottom" style="width:43.86%;padding:0pt 2.4pt 0pt 18pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;">President and Chief Executive Officer</font></p>
				</td>
			</tr>
		</table></div>
		<p style="margin:3pt 0pt 0pt;line-height:120%;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">&#xFEFF;</font>
		</p>
		<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">

		</p>
		<p><font size="1"> </font></p><div style="width:100%">

		<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 9pt">

			<font style="display: inline;font-size:9pt;">II</font><font style="display: inline;font-size:9pt;">&#8209;4</font>

		</p>

</div><hr size="3" style="color:#999999" width="100%" align="center"></hr><p style="page-break-after:always">&nbsp;</p><div style="width:100%">

		<p style="margin:0pt;line-height:120%;font-family:Times New Roman;font-size: 10pt">

			&nbsp;

		</p>

</div>
		<p style="margin:0pt;font-family:Times New Roman;;font-size: 10pt"><font style="display: inline;"></font>
		</p>
		<p style="margin:3pt 0pt 0pt;line-height:120%;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">&#xFEFF;</font>
		</p>
		<p style="margin:0pt 0pt 30pt;line-height:120%;text-align:center;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;color:#000000;text-decoration:underline;">POWER OF ATTORNEY</font><a name="Power_of_Attorney"></a>
		</p>
		<p style="margin:0pt 0pt 12pt;line-height:120%;text-indent:36pt;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">The undersigned officers and directors of Alimera Sciences, Inc., a Delaware corporation, do hereby constitute and appoint Richard S. Eiswirth, Jr.</font><font style="display: inline;">,</font><font style="display: inline;"> J. Philip Jones, </font><font style="display: inline;">and Christopher S. Visick, </font><font style="display: inline;">and </font><font style="display: inline;">any</font><font style="display: inline;"> of them, the lawful attorneys-in-fact and agents with full power and authority to do any and all acts and things and to execute any and all instruments which said attorneys and agents, and </font><font style="display: inline;">any</font><font style="display: inline;"> of them, determine may be necessary or advisable or required to enable said corporation to comply with the Securities Act of 1933, as amended, and any rules or regulations or requirements of the Securities and Exchange Commission in connection with this Registration Statement. Without limiting the generality of the foregoing power and authority, the powers granted include the power and authority to sign the names of the undersigned officers and directors in the capacities indicated below to this Registration Statement, to any and all amendments, both pre-effective and post-effective, and supplements to this Registration Statement, and to any and all instruments or documents filed as part of or in conjunction with this Registration Statement or amendments or supplements thereof, and each of the undersigned hereby ratifies and confirms all that said attorneys and agents, or either one of them, shall do or cause to be done by virtue hereof. This Power of Attorney may be signed in several counterparts.</font>
		</p>
		<p style="margin:0pt 0pt 12pt;line-height:120%;text-indent:36pt;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;">IN WITNESS WHEREOF</font><font style="display: inline;">, each of the undersigned has executed this Power of Attorney as of the date indicated.</font>
		</p>
		<p style="margin:0pt 0pt 19pt;line-height:120%;text-indent:36pt;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">Pursuant to the requirements of the Securities Act of 1933, as amended, this Registration Statement has been signed below by the following persons in the capacities and on the dates indicated.</font>
		</p>
		<div style="width:100%"><table cellpadding="0" cellspacing="0" align="center" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
			<tr>
				<td valign="top" style="width:36.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;padding:0pt 3.6pt 0pt 3.6pt;height:1.00pt">
					<p style="margin:0pt;font-family:Times New Roman;height:1.00pt;overflow:hidden;font-size: 1pt">
						<font style="display: inline;font-size:1pt;">&#xFEFF;</font></p>
				</td>
				<td valign="top" style="width:40.38%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;padding:0pt 3.6pt 0pt 3.6pt;height:1.00pt">
					<p style="margin:0pt;font-family:Times New Roman;height:1.00pt;overflow:hidden;font-size:0pt;">
						&nbsp;</p>
				</td>
				<td valign="top" style="width:23.50%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;padding:0pt 3.6pt 0pt 3.6pt;height:1.00pt">
					<p style="margin:0pt;font-family:Times New Roman;height:1.00pt;overflow:hidden;font-size:0pt;">
						&nbsp;</p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:36.12%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;text-decoration:underline;">Signature</font></p>
				</td>
				<td valign="top" style="width:40.38%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;text-decoration:underline;">Title</font></p>
				</td>
				<td valign="top" style="width:23.50%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;text-decoration:underline;">Date</font></p>
				</td>
			</tr>
			<tr>
				<td valign="middle" style="width:36.12%;background-color: #CCEEFF;padding:0pt 2.4pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;text-decoration:underline;">/s/ Richard S. Eiswirth, Jr.</font></p>
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Richard S. Eiswirth, Jr.</font></p>
				</td>
				<td valign="middle" style="width:40.38%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;">President, Chief Executive Officer and Director (Principal Executive Officer)</font></p>
				</td>
				<td valign="middle" style="width:23.50%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;color:#000000;font-size:9pt;">October 29, 2021</font></p>
				</td>
			</tr>
			<tr>
				<td valign="middle" style="width:36.12%;padding:0pt 2.4pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;text-decoration:underline;">/s/ J. Philip Jones</font></p>
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">J. Philip Jones</font></p>
				</td>
				<td valign="middle" style="width:40.38%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;">Chief Financial Officer (Principal Financial and Accounting Officer)</font></p>
				</td>
				<td valign="middle" style="width:23.50%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;color:#000000;font-size:9pt;">October 29, 2021</font></p>
				</td>
			</tr>
			<tr>
				<td valign="middle" style="width:36.12%;background-color: #CCEEFF;padding:0pt 2.4pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;text-decoration:underline;">/s/ C. Daniel Myers</font></p>
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">C. Daniel Myers</font></p>
				</td>
				<td valign="middle" style="width:40.38%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;">Chairman of the Board of Directors</font></p>
				</td>
				<td valign="middle" style="width:23.50%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;color:#000000;font-size:9pt;">October 29, 2021</font></p>
				</td>
			</tr>
			<tr>
				<td valign="middle" style="width:36.12%;padding:0pt 2.4pt 0pt 3.6pt;">
					<p style="margin:0pt;border-bottom:1pt solid #000000 ;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;">/s/ James </font><font style="display: inline;color:#000000;">R. </font><font style="display: inline;color:#000000;">Largent</font></p>
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">James </font><font style="display: inline;">R. </font><font style="display: inline;">Largent</font></p>
				</td>
				<td valign="middle" style="width:40.38%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;">Lead Independent Director</font></p>
				</td>
				<td valign="middle" style="width:23.50%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;color:#000000;font-size:9pt;">October 29, 2021</font></p>
				</td>
			</tr>
			<tr>
				<td valign="middle" style="width:36.12%;background-color: #CCEEFF;padding:0pt 2.4pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;text-decoration:underline;">/s/ Brian K. Halak</font></p>
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Brian K. Halak, Ph.D.</font></p>
				</td>
				<td valign="middle" style="width:40.38%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;">Director</font></p>
				</td>
				<td valign="middle" style="width:23.50%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;color:#000000;font-size:9pt;">October 29, 2021</font></p>
				</td>
			</tr>
			<tr>
				<td valign="middle" style="width:36.12%;padding:0pt 2.4pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;text-decoration:underline;">/s/ Garheng Kong</font></p>
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Garheng Kong, M.D., Ph.D.</font></p>
				</td>
				<td valign="middle" style="width:40.38%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;">Director</font></p>
				</td>
				<td valign="middle" style="width:23.50%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;color:#000000;font-size:9pt;">October 29, 2021</font></p>
				</td>
			</tr>
			<tr>
				<td valign="middle" style="width:36.12%;background-color: #CCEEFF;padding:0pt 2.4pt 0pt 3.6pt;">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;text-decoration:underline;">/s/ Peter J. Pizzo, III</font></p>
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Peter J. Pizzo, III</font></p>
				</td>
				<td valign="middle" style="width:40.38%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;">Director</font></p>
				</td>
				<td valign="middle" style="width:23.50%;background-color: #CCEEFF;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;color:#000000;font-size:9pt;">October 29, 2021</font></p>
				</td>
			</tr>
			<tr>
				<td valign="middle" style="width:36.12%;padding:0pt 2.4pt 0pt 3.6pt;">
					<p style="margin:0pt;border-bottom:1pt solid #000000 ;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;">/s/ </font><font style="display: inline;color:#000000;">John Snisarenko</font></p>
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">John Snisarenko</font></p>
				</td>
				<td valign="middle" style="width:40.38%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;color:#000000;">Director</font></p>
				</td>
				<td valign="middle" style="width:23.50%;padding:0pt 3.6pt 0pt 3.6pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;color:#000000;font-size:9pt;">October 29, 2021</font></p>
				</td>
			</tr>
		</table></div>
		<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">&#xFEFF;</font>
		</p>
		<p><font size="1"> </font></p><div style="width:100%">

		<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 9pt">

			<font style="display: inline;font-size:9pt;">II</font><font style="display: inline;font-size:9pt;">&#8209;4</font>

		</p>

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{"company-data": {"conformed-name": "ALIMERA SCIENCES INC", "cik": "0001267602", "assigned-sic": "2834", "irs-number": "200028718", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-260617", "film-number": "211364337"}, "business-address": {"street1": "6120 WINDWARD PARKWAY", "street2": "STE 290", "city": "ALPHARETTA", "state": "GA", "zip": "30005", "phone": "678-990-5740"}, "mail-address": {"street1": "6120 WINDWARD PARKWAY", "street2": "STE 290", "city": "ALPHARETTA", "state": "GA", "zip": "30005"}}
alim s-8
As filed with the Securities and Exchange Commission on
Octo
ber
29
, 2021
Registration No. 333-
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
___________________
﻿
FORM S
‑
8
REGISTRATION STATEMENT
Under
The Securities Act of 1933
___________________
﻿
ALIMERA SCIENCES, INC.
(Exact name of registrant as specified in its charter)
Delaware
(State or other jurisdiction of incorporation or organization)
20-0028718
(IRS Employer
Identification No.)
﻿
6120 Windward Parkway, Suite 290
Alpharetta, GA 30005
(Address of principal executive offices) (Zip Code)
___________________
﻿
ALIMERA SCIENCES, INC. 201
9
OMNIBUS
INCENTIVE PLAN
ALIMERA SCIENCES, INC. 2010 EMPLOYEE STOCK PURCHASE PLAN
(Full title of the
p
lan)
___________________
﻿
Richard S. Eiswirth, Jr.
President and Chief Executive Officer
6120 Windward Parkway, Suite 290
Alpharetta, GA 30005
(Name and address of agent for service)
(678) 990-5740
(Telephone number, including area code, of agent for service)
﻿
Copies to:
﻿
Charles D. Vaughn
Christopher S. Visick
Nelson Mullins Riley & Scarborough LLP
Vice President and General Counsel
Atlantic Station, Suite 1700
6120 Windward Parkway, Suite 290
201 17
th
Street NW
Alpharetta, GA 30005
Atlanta, GA 30363
(678) 990-5740
(404) 322-6000
___________________
﻿
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer a smaller reporting company or an emerging growth company. See the definitions of "large accelerated filer," "accelerated filer," "smaller reporting company," and "emerging growth company" in Rule 12b-2 of the Exchange Act.
Large accelerated filer
☐
Accelerated filer
☐
Non-accelerated filer
☒
Smaller reporting company
☒
﻿
Emerging Growth Company
☐
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act
☐
﻿
II-
1
CALCULATION OF REGISTRATION FEE
﻿
(1)
﻿
Title of Securities to be Registered
Amount to be Registered
(1)
Proposed Maximum Offering Price per Share
(2)
Proposed Maximum Aggregate Offering Price
(2)
Amount of Registration Fee
Common Stock,
$0.01
par value –
2019 Omnibus Incentive Plan
1,000,000 (3)
$4.52
$4,520,000.00
$419.01
Common Stock,
$0.01
par value –
201
0
Employee Stock Purchase Plan
13,812 (4)
$4.52
$62,430.24
$5.79
Total
1,013,812
N/A
$4,582,430.24
$424.80
_______________________________
(1)
The shares
registered hereunder
include:
(a) an additional
1,000
,000 shares of the Common Stock, $0.01 par value ("Common Stock"), of Alimera Sciences, Inc.
(the "Company" or the "registrant")
reserved for issuance pursuant to the Alimera Sciences, Inc. 201
9
Omnibus
Incentive Plan
(the "2019 Plan")
; and (b)
13,812
shares of Common Stock
reserved for issuance pursuant to the Alimera Sciences, Inc. 2010 Employee Stock Purchase Plan (the "2010 ESPP").
This Registration Statement
also cover
s
any additional shares of Common Stock that become issuable under
the 2019
Plan
or the 2010 ESPP
by reason of any stock dividend, stock split, recapitalization or other similar transaction effected without the receipt of consideration
that
results in an increase in the number of the outstanding shares of Common Stock.
﻿
(2)
Estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rule 457(c) and
Rule 457
(h)(1) under the
Securities Act of 1933, as amended (the "Securities Act")
. The offering price per share and aggregate offering price for the shares of Common Stock are based upon the average of the high and low prices of the Common Stock as reported on The N
asdaq
Global Market on
October
26
, 2021.
﻿
(3)
Represents
1,000,000
shares of Common Stock that were added to the shares of Common Stock authorized for issuance under the 20
19
Plan
under an
amend
ment approved by the Company's
stockholder
s
on June 15, 2021
.
﻿
(4)
Represents
13,812
shares of
Common Stock that were
automatically added to the shares of Common Stock authorized for issuance under the 2010 ESPP on January 1, 202
1
pursuant to an "evergreen" provision contained in the 2010 ESPP
.
Under that provision, on January 1 of each year from January 1, 2011 through and including January 1, 202
1
, the aggregate number of shares of Common Stock available for purchase during the life of the 2010 ESPP automatically increased by the number of shares of Common Stock necessary to cause the number of shares of Common Stock then available for purchase to be restored to 32,961 shares of Common Stock
(which amount takes into account the
Company
's one-for-15 reverse stock split that became effective on November 14, 2019)
.
﻿
II-
2
INCORPORATION OF DOCUMENTS BY REFERENCE
This Registration Statement is being filed for the purpose of increasing the number of securities of the same class as other securities for which Registration Statements of the Registrant on Form S-8 relating to the same employee benefit plans are effective.
This Registration Statement is being filed for the purpose of increasing the number of securities of the same class as other securities for which Registration Statements of the Registrant on Form S-8 relating to the same employee benefit plan are effective.
Pursuant to General Instruction E to Form S-8, this Registration Statement hereby incorporates by reference the contents of
:
(a)
the Registration Statement on Form S-8 relating to the Alimera Sciences, Inc. 201
9
Omnibus Incentive
Plan filed with the SEC on
June 19, 2019
(File No. 333-
232206
)
; and
﻿
(b)
the Registration Statements on Form S-8 relating to the Alimera Sciences, Inc. 2010 Employee Stock Purchase Plan filed with the SEC
on May 14, 2010 (File No. 333-166822), March 25, 2011 (File No. 333-173095), April 4, 2012 (File No. 333-180567), March 28, 2013 (File No. 333-187600), March 7, 2014 (File No. 333-194381), January 20, 2015 (File No. 333-201606), January 19, 2016 (File No. 333-209035), January 6, 2017 (File No. 333-215451), January 11, 2018, as amended by Post-Effective Amendment No. 1 on January 12, 2018 (File No. 333-222508), January 16, 2019 (File No. 333-229280),
and November 2, 202
0
(File No. 333-2
49811
)
,
in each case except for Item 8, Exhibits, with respect to which the Exhibit Index below is incorporated herein by reference.
II
‑4
E
XHIBIT INDEX
﻿
Exhibit Number
Exhibit
4.1
Restated Certificate of Incorporation of Registrant, as amended on various dates (filed as Exhibit 3.1 to the Registrant's Annual Report on Form 10-K for the year ended December 31, 2020, as filed on March 5, 2021, and incorporated herein by reference)
4.2
Amended and Restated Bylaws of the Registrant, as amended (filed as Exhibit 3.2 to the Registrant's Annual Report on Form 10-K for the year ended December 31, 2020, as filed on March 5, 2021, and incorporated herein by reference)
5.1
Opinion and consent of Nelson Mullins Riley & Scarborough LLP
23.1
Consent of Grant Thornton LLP, Independent Registered Public Accounting Firm
23.2
Consent of Nelson Mullins Riley & Scarborough LLP (included in Exhibit 5.1)
24.1
Power of Attorney. Reference is made to the Power of Attorney following the signature page of this Registration Statement
99.1
Alimera Sciences, Inc. 2019 Omnibus Incentive Plan (incorporated by reference to Exhibit 10.60 to the Company's Current Report on Form 8-K filed on June 18, 2019)
99.2
Form of Stock Option Agreement under the Alimera Sciences, Inc. 2019 Omnibus Incentive Plan (incorporated by reference to Exhibit 10.61 to the Company's Current Report on Form 8-K filed on June 18, 2019)
99.3
Form of Restricted Stock Agreement under the Alimera Sciences, Inc. 2019 Omnibus Incentive Plan (filed as Exhibit 10.5.C to the Registrant's Quarterly Report on Form 10-Q, as filed May 6, 2020, and incorporated herein by reference)
99.4
Form of Restricted Stock Unit Agreement under the Alimera Sciences, Inc. 2019 Omnibus Incentive Plan (filed as Exhibit 10.5.D to the Registrant's Quarterly Report on Form 10-Q, as filed May 6, 2020, and incorporated herein by reference)
99.5
UK Sub-Plan to the Alimera Sciences, Inc. 2019 Omnibus Incentive Plan
99.6
Form of UK Sub-Plan Stock Option Agreement
99.7
2010 Employee Stock Purchase Plan (filed as Exhibit 10.10 to Amendment No. 4 to the Registrant's Registration Statement on Form S-1 (SEC File No. 333-162782), as filed on April 6, 2010, and incorporated herein by reference)
99.8
Amendment No. 1 to 2010 Employee Stock Purchase Plan (filed as Exhibit 10.7.A to the Registrant's Annual Report on Form 10-K, as filed March 13, 2015, and incorporated herein by reference)
99.9
Amendment No. 2 to 2010 Employee Stock Purchase Plan (filed as Exhibit 99.3 to the Registrant's Registration Statement on Form S-8, as filed November 2, 2020, and incorporated herein by reference)
﻿
II
‑4
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, as amended, the
r
egistrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Alpharetta, State of Georgia on this
29th
day of
October
,
2021
.
﻿
ALIMERA SCIENCES, INC.
﻿
﻿
By:
/s/ Richard S. Eiswirth, Jr.
﻿
Richard S. Eiswirth, Jr.
﻿
President and Chief Executive Officer
﻿
II
‑4
﻿
POWER OF ATTORNEY
The undersigned officers and directors of Alimera Sciences, Inc., a Delaware corporation, do hereby constitute and appoint Richard S. Eiswirth, Jr.
,
J. Philip Jones,
and Christopher S. Visick,
and
any
of them, the lawful attorneys-in-fact and agents with full power and authority to do any and all acts and things and to execute any and all instruments which said attorneys and agents, and
any
of them, determine may be necessary or advisable or required to enable said corporation to comply with the Securities Act of 1933, as amended, and any rules or regulations or requirements of the Securities and Exchange Commission in connection with this Registration Statement. Without limiting the generality of the foregoing power and authority, the powers granted include the power and authority to sign the names of the undersigned officers and directors in the capacities indicated below to this Registration Statement, to any and all amendments, both pre-effective and post-effective, and supplements to this Registration Statement, and to any and all instruments or documents filed as part of or in conjunction with this Registration Statement or amendments or supplements thereof, and each of the undersigned hereby ratifies and confirms all that said attorneys and agents, or either one of them, shall do or cause to be done by virtue hereof. This Power of Attorney may be signed in several counterparts.
IN WITNESS WHEREOF
, each of the undersigned has executed this Power of Attorney as of the date indicated.
Pursuant to the requirements of the Securities Act of 1933, as amended, this Registration Statement has been signed below by the following persons in the capacities and on the dates indicated.
﻿
Signature
Title
Date
/s/ Richard S. Eiswirth, Jr.
Richard S. Eiswirth, Jr.
President, Chief Executive Officer and Director (Principal Executive Officer)
October 29, 2021
/s/ J. Philip Jones
J. Philip Jones
Chief Financial Officer (Principal Financial and Accounting Officer)
October 29, 2021
/s/ C. Daniel Myers
C. Daniel Myers
Chairman of the Board of Directors
October 29, 2021
/s/ James
R.
Largent
James
R.
Largent
Lead Independent Director
October 29, 2021
/s/ Brian K. Halak
Brian K. Halak, Ph.D.
Director
October 29, 2021
/s/ Garheng Kong
Garheng Kong, M.D., Ph.D.
Director
October 29, 2021
/s/ Peter J. Pizzo, III
Peter J. Pizzo, III
Director
October 29, 2021
/s/
John Snisarenko
John Snisarenko
Director
October 29, 2021
﻿
II
‑4