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<!-- Field: Rule-Page --><DIV ALIGN="LEFT"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid; border-bottom: Black 1pt solid; width: 100%">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

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<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0 0 0 0.5in; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>As
filed with the Securities and Exchange Commission on December 30, 2016</B></FONT></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>Registration
No. 333-</B></FONT></P>


<P STYLE="font: bold 11pt Times New Roman, Times, Serif; margin: 0; text-align: center; border-top: Black 2.5pt double"><FONT STYLE="font-family: Times New Roman, Times, Serif">UNITED
STATES SECURITIES AND EXCHANGE COMMISSION</FONT></P>

<P STYLE="font: bold 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">Washington,
D.C. 20549</FONT></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">________________</FONT></P>

<P STYLE="font: bold 13pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">FORM
S-8<BR>
REGISTRATION STATEMENT</FONT></P>

<P STYLE="font: bold 13pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">UNDER
THE SECURITIES ACT OF 1933</FONT></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">________________</FONT></P>

<P STYLE="font: bold 16pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">OHR
PHARMACEUTICAL, INC.</FONT></P>

<P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">(Exact
name of Registrant as specified in its charter)</FONT></P>

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    <TD STYLE="width: 50%; padding: 0; text-align: center; text-indent: 0; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Delaware</B></FONT></TD>
    <TD STYLE="width: 50%; padding: 0; text-align: center; vertical-align: bottom; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>46-5622433</B></FONT></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="padding: 0; text-align: center; text-indent: 0; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">(State
    or other jurisdiction of</FONT><FONT STYLE="font-family: Times New Roman, Times, Serif"><BR>
    <FONT STYLE="font-size: 8pt">incorporation or organization)</FONT></FONT></TD>
    <TD STYLE="padding-left: 0; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">(I.R.S.
    Employer</FONT><FONT STYLE="font-family: Times New Roman, Times, Serif"><BR>
    <FONT STYLE="font-size: 8pt">Identification No.)</FONT></FONT></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
    <TD STYLE="padding-left: 5.4pt; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: bottom; font-family: Times New Roman, Times, Serif; text-align: center">
    <TD STYLE="padding: 0; text-align: center; text-indent: 0; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>800
    Third Ave, 11<SUP>th</SUP> Floor</B></FONT><FONT STYLE="font-family: Times New Roman, Times, Serif"><BR>
    <FONT STYLE="font-size: 10pt"><B>New York, NY</B></FONT></FONT></TD>
    <TD STYLE="padding-right: 0; padding-left: 0; font-family: Times New Roman, Times, Serif"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>&nbsp;</B></FONT></P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>10977</B></FONT></P></TD></TR>
<TR STYLE="vertical-align: bottom; font-family: Times New Roman, Times, Serif; text-align: center">
    <TD STYLE="padding: 0; text-align: center; text-indent: 0; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">(Address
    of Principal Executive Offices)&nbsp;&nbsp;</FONT></TD>
    <TD STYLE="padding-left: 0; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">(Zip
    Code)</FONT></TD></TR>
</TABLE>
<P STYLE="font: 6pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">________________</FONT></P>

<P STYLE="font: 16pt Times New Roman, Times, Serif; margin: 0; text-align: center; background-color: white"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>Ohr
Pharmaceutical, Inc. 2014 Stock Incentive Plan </B></FONT></P>

<P STYLE="font: 16pt Times New Roman, Times, Serif; margin: 0; text-align: center; background-color: white"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>Ohr
Pharmaceutical, Inc. 2016 Consolidated Stock Incentive Plan</B></FONT></P>

<P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">(Full
title of the plans)</FONT></P>

<P STYLE="font: bold 11pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Sam
Backenroth</FONT><FONT STYLE="font-family: Times New Roman, Times, Serif"><BR>
<FONT STYLE="font-size: 10pt">Chief Financial Officer</FONT><BR>
<FONT STYLE="font-size: 10pt">Ohr Pharmaceutical, Inc.</FONT><BR>
<FONT STYLE="font-size: 10pt">800 Third Avenue, 11th Floor</FONT><BR>
<FONT STYLE="font-size: 10pt">New York, New York 10022</FONT><BR>
<FONT STYLE="font-size: 8pt; font-weight: normal">(Name and address of agent for service)</FONT></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 8pt 0 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>(212)
682-8452</B></FONT></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 9pt">(</FONT><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Telephone
number, including area code, of agent for service)</FONT></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">________________</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-weight: normal"><I>Copies
of all correspondence to:</I></FONT></P>

<P STYLE="font: bold 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>Aurora
Cassirer</B>, Esq.<BR>
Joseph Walsh, Esq.<BR>
Troutman Sanders LLP<BR>
875 Third Avenue</FONT></P>

<P STYLE="font: bold 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">New
York, New York 10022<BR>
<FONT STYLE="font-size: 10pt">(212) 704-6000</FONT></FONT></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">________________</FONT></P>

<P STYLE="font: 9pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: justify; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Indicate
by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer or a smaller
reporting company. See definitions of &#8220;large accelerated filer,&#8221; &#8220;accelerated filer,&#8221; and &#8220;smaller
reporting company&#8221; in Rule 12b-2 of the Exchange Act.</FONT></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-indent: 0.25in"></P>

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<TR STYLE="vertical-align: top; text-align: left; font-family: Times New Roman, Times, Serif">
    <TD NOWRAP STYLE="width: 14%; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">Large accelerated filer</FONT></TD>
    <TD STYLE="width: 36%; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&#9744;&nbsp;</FONT></TD>
    <TD STYLE="width: 17%; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">Accelerated filer</FONT></TD>
    <TD STYLE="width: 33%; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&#9746;</FONT></TD></TR>
<TR STYLE="vertical-align: top; text-align: left; font-family: Times New Roman, Times, Serif">
    <TD NOWRAP STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">Non-accelerated filer</FONT></TD>
    <TD NOWRAP STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&#9744;&nbsp;(Do not check if a smaller reporting company)&#9;</FONT></TD>
    <TD NOWRAP STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">Smaller reporting company</FONT></TD>
    <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&#9744;&nbsp;</FONT></TD></TR>
</TABLE>

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<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">CALCULATION
OF REGISTRATION FEE</FONT></P>

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<TR STYLE="vertical-align: bottom; font-family: Times New Roman, Times, Serif">
    <TD STYLE="width: 35%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Title
    of</FONT><FONT STYLE="font-family: Times New Roman, Times, Serif"><BR>
    <FONT STYLE="font-size: 10pt">Securities to be Registered </FONT></FONT></TD>
    <TD STYLE="width: 15%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Amount
    to be Registered<SUP>(1)</SUP></FONT></TD>
    <TD STYLE="width: 15%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Proposed</FONT><FONT STYLE="font-family: Times New Roman, Times, Serif"><BR>
    <FONT STYLE="font-size: 10pt">Maximum</FONT><BR>
    <FONT STYLE="font-size: 10pt">Offering Price</FONT><BR>
    <FONT STYLE="font-size: 10pt">Per Share</FONT></FONT></TD>
    <TD STYLE="width: 16%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Proposed</FONT><FONT STYLE="font-family: Times New Roman, Times, Serif"><BR>
    <FONT STYLE="font-size: 10pt">Maximum</FONT><BR>
    <FONT STYLE="font-size: 10pt">Aggregate</FONT><BR>
    <FONT STYLE="font-size: 10pt">Offering Price</FONT></FONT></TD>
    <TD STYLE="width: 19%; border-top: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Amount
    of <BR>
Registration Fee </FONT></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 0; padding-left: 0; text-indent: 0; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common
    Stock, $0.0001 par value per share </FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,179,000<SUP>(2)</SUP></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$7.73<SUP>(3)</SUP></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$16,843,670</FONT></TD>
    <TD STYLE="border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$1,952<SUP>(3)</SUP></FONT></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 0; padding-left: 0; text-indent: 0; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common
    Stock, $0.0001 par value per share</FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">120,550<SUP>(4)</SUP></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$7.93<SUP>(5)</SUP></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$955,962</FONT></TD>
    <TD STYLE="border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$111<SUP>(5)</SUP></FONT></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="width: 35%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 0; padding-left: 0; text-indent: 0; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common
    Stock, $0.0001 par value per share</FONT></TD>
    <TD STYLE="width: 15%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">80,000<SUP>(6)</SUP></FONT></TD>
    <TD STYLE="width: 15%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$3.23<SUP>(7)</SUP></FONT></TD>
    <TD STYLE="width: 16%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$258,400</FONT></TD>
    <TD STYLE="width: 19%; border-top: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$30<SUP>(7)</SUP></FONT></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 0; padding-left: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common
    Stock, $0.0001 par value per share</FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,681,275<SUP>(8)</SUP></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$1.625<SUP>(9)</SUP></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$4,357,072</FONT></TD>
    <TD STYLE="border-bottom: Black 1.5pt double; padding-right: 4.3pt; padding-left: 4.3pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$505<SUP>(9)</SUP></FONT></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 4.3pt; padding-left: 4.3pt; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9;<B>Total</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 4.3pt; padding-left: 4.3pt; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>5,060,825</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 4.3pt; padding-left: 4.3pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 4.3pt; padding-left: 4.3pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>$22,415,104</B></FONT></TD>
    <TD STYLE="border-bottom: Black 1pt solid; padding-right: 4.3pt; padding-left: 4.3pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>$2,598</B></FONT></TD></TR>
</TABLE>
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<TD STYLE="width: 0; font-family: Times New Roman, Times, Serif"></TD><TD STYLE="width: 0.25in; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">(1)</FONT></TD><TD STYLE="text-align: justify; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">Pursuant
                                         to Rule 416(a) under the Securities Act of 1933, as amended (the &#8220;Securities Act&#8221;),
                                         this Registration Statement also covers an indeterminate number of additional shares
                                         common stock, $0.0001 par value per share (the &#8220;Common Stock&#8221;), of the Registrant,
                                         which may be offered and issued to prevent dilution resulting from adjustments as a result
                                         of stock dividends, stock splits, reverse stock splits, recapitalizations, reclassifications,
                                         mergers, split-ups, reorganizations, consolidations and other capital adjustments.</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 9pt Times New Roman, Times, Serif; margin-top: 4pt; margin-bottom: 0"><TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
<TD STYLE="width: 0; font-family: Times New Roman, Times, Serif"></TD><TD STYLE="width: 0.25in; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">(2)</FONT></TD><TD STYLE="text-align: justify; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">Represents
                                         shares of Common Stock issuable pursuant to outstanding but unexercised stock options
                                         previously granted under the Ohr Pharmaceutical, Inc. 2014 Stock Incentive Plan (the
                                         &#8220;2014 Plan&#8221;).</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 9pt Times New Roman, Times, Serif; margin-top: 4pt; margin-bottom: 0"><TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
<TD STYLE="width: 0; font-family: Times New Roman, Times, Serif"></TD><TD STYLE="width: 0.25in; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">(3)</FONT></TD><TD STYLE="text-align: justify; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">Estimated
                                         solely for the purpose of determining the amount of the registration fee in accordance
                                         with Rule 457(h) under the Securities Act, based upon the weighted average exercise price
                                         of $7.73 of the outstanding but unexercised stock options previously granted under the
                                         2014 Plan.</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 9pt Times New Roman, Times, Serif; margin-top: 4pt; margin-bottom: 0"><TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
<TD STYLE="width: 0; font-family: Times New Roman, Times, Serif"></TD><TD STYLE="width: 0.25in; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">(4)</FONT></TD><TD STYLE="text-align: justify; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">Represents
                                         shares of Common Stock issuable pursuant to outstanding but unexercised warrants previously
                                         granted under the 2014 Plan.</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 9pt Times New Roman, Times, Serif; margin-top: 4pt; margin-bottom: 0"><TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
<TD STYLE="width: 0; font-family: Times New Roman, Times, Serif"></TD><TD STYLE="width: 0.25in; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">(5)</FONT></TD><TD STYLE="text-align: justify; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">Estimated
                                         solely for the purpose of determining the amount of the registration fee in accordance
                                         with Rule 457(h) under the Securities Act, based upon the weighted average exercise price
                                         of $7.93 of the outstanding but unexercised warrants previously granted under the 2014
                                         Plan.</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 9pt Times New Roman, Times, Serif; margin-top: 4pt; margin-bottom: 0"><TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
<TD STYLE="width: 0; font-family: Times New Roman, Times, Serif"></TD><TD STYLE="width: 0.25in; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">(6)</FONT></TD><TD STYLE="text-align: justify; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">Represents
                                         shares of Common Stock issuable pursuant to outstanding but unexercised stock options
                                         previously granted under the Ohr Pharmaceutical, Inc. 2016 Consolidated Stock Incentive
                                         Plan (the &#8220;2016 Plan&#8221;).</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 9pt Times New Roman, Times, Serif; margin-top: 4pt; margin-bottom: 0"><TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
<TD STYLE="width: 0; font-family: Times New Roman, Times, Serif"></TD><TD STYLE="width: 0.25in; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">(7)</FONT></TD><TD STYLE="text-align: justify; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">Estimated
                                         solely for the purpose of determining the amount of the registration fee in accordance
                                         with Rule 457(h) under the Securities Act, based upon the weighted average exercise price
                                         of $3.23 of the outstanding but unexercised stock options previously granted under the
                                         2016 Plan.</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 9pt Times New Roman, Times, Serif; margin-top: 4pt; margin-bottom: 0"><TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
<TD STYLE="width: 0; font-family: Times New Roman, Times, Serif"></TD><TD STYLE="width: 0.25in; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">(8)</FONT></TD><TD STYLE="text-align: justify; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">Represents
                                         shares of Common Stock issuable pursuant to awards to be issued under the Ohr Pharmaceutical,
                                         Inc. 2016 Plan.</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 9pt Times New Roman, Times, Serif; margin-top: 4pt; margin-bottom: 0"><TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
<TD STYLE="width: 0; font-family: Times New Roman, Times, Serif"></TD><TD STYLE="width: 0.25in; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">(9)</FONT></TD><TD STYLE="text-align: justify; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">Estimated
                                                                                                                                                                                                                    solely for the purpose of calculating the registration fee and computed in accordance
                                                                                                                                                                                                                    with Rule 457(c) and (h)&nbsp;under the Securities Act using the average of the high
                                                                                                                                                                                                                    and low sale prices of the Common Stock as reported on The NASDAQ Capital Market on December 27, 2016, which was $1.625 per
                                                                                                                                                                                                                    share.</FONT></TD></TR></TABLE>

<P STYLE="font: 9pt Times New Roman, Times, Serif; margin: 0 0 0 0.25in; text-align: justify; text-indent: -0.25in"></P>

<P STYLE="font: 9pt Times New Roman, Times, Serif; margin: 0 0 0 0.25in; text-indent: -0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif"><BR>
<BR></FONT></P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>PART
I</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>INFORMATION
REQUIRED IN THE SECTION 10(a) PROSPECTUS</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 -11pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>ITEM
1.&#9;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B><U>Plan Information</U>.</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Not
required to be filed with this Registration Statement.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 -11pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>ITEM
2.&#9;<U></U></B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B><U>Registrant Information and Employee Plan Annual Information</U>.</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Not
required to be filed with this Registration Statement.</FONT></P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">PART
II</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>INFORMATION
REQUIRED IN THE REGISTRATION STATEMENT</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 -11pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>ITEM
3.&#9;<U></U></B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B><U>Incorporation of Documents by Reference</U>.</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">The
Registrant hereby incorporates by reference into this Registration Statement the following documents previously filed by the Registrant
with the Securities and Exchange Commission (the &#8220;Commission&#8221;):</FONT></P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 11pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 6pt"><TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
<TD STYLE="width: 0.85in; font-family: Times New Roman, Times, Serif"></TD><TD STYLE="width: 0.25in; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9679;</FONT></TD><TD STYLE="text-align: justify; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">the
                                         Registrant&#8217;s Annual Report on Form 10-K (No. <FONT STYLE="background-color: white">001-35963</FONT>)
                                         for the fiscal year ended September 30, 2016, filed with the Commission on December 22,
                                         2016; </FONT></TD></TR>

                                                                                                                                  <TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
<TD STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</TD><TD STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</TD><TD STYLE="text-align: justify; font-family: Times New Roman, Times, Serif">&nbsp;</TD></TR>

<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
<TD STYLE="font-family: Times New Roman, Times, Serif"></TD><TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9679;</FONT></TD><TD STYLE="text-align: justify; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">the
                                                                                                                                                                                                                Registrant&#8217;s Current Report on Form 8-K (No. <FONT STYLE="background-color: white">001-35963</FONT>)
                                                                                                                                                                                                                filed with the Commission on December 8, 2016; and </FONT></TD></TR>                                                                                                           <TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
<TD STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</TD><TD STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</TD><TD STYLE="text-align: justify; font-family: Times New Roman, Times, Serif">&nbsp;</TD></TR>

<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
<TD STYLE="font-family: Times New Roman, Times, Serif"></TD><TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9679;</FONT></TD><TD STYLE="text-align: justify; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
                                         description of the Registrant&#8217;s common stock<FONT STYLE="background-color: white">,
                                         </FONT>contained in the Registrant&#8217;s Registration Statement on Form<FONT STYLE="background-color: white">
                                         8-A </FONT>(File No. 001-35963), filed by the Registrant with the Commission on June
                                         11, 2013, including any amendments or reports filed for the purpose of updating such
                                         description.</FONT></TD></TR></TABLE>

<P STYLE="margin-top: 0; margin-bottom: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">All
documents that the Registrant subsequently filed pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Securities and Exchange
Act of 1934, as amended, prior to the filing of a post-effective amendment to this Registration Statement which indicates that
all of the shares of common stock of the Registrant offered have been sold or which deregisters all of such shares of common stock
then remaining unsold, shall be deemed to be incorporated by reference in this Registration Statement and to be a part hereof
from the date of the filing of such documents.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Any
statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified
or superseded to the extent that a statement contained herein or in any other subsequently filed document which also is or is
deemed to be incorporated by reference herein modifies or supersedes such statement. Any such statement so modified or superseded
shall not be deemed, except as so modified or superseded, to constitute a part of this Registration Statement.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Notwithstanding
the above, information that is &#8220;furnished to&#8221; the Commission shall not be deemed &#8220;filed with&#8221; the Commission
and shall not be deemed incorporated by reference into this Registration Statement.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 -11pt"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>ITEM
4.&#9;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B><U>Description of Securities</U>.</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Not
applicable.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 -11pt"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>ITEM
5.&#9;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B><U>Interests of Named Experts and Counsel</U>.</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Not
applicable.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 -11pt"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>ITEM
6.&#9;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B><U>Indemnification of Directors and Officers</U>.</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">The
Registrant is incorporated under the laws of the State of Delaware. Section&nbsp;145 (&#8220;Section 145&#8221;) of the General
Corporation Law of the State of Delaware, as the same exists or may hereafter be amended (the &#8220;DGCL&#8221;), provides that
a Delaware corporation may indemnify any persons who were, are or are threatened to be made, parties to any threatened, pending
or completed action, suit or proceeding, whether civil, criminal, administrative or investigative (other than an action by or
in the right of such corporation), by reason of the fact that such person is or was an officer, director, employee or agent of
such corporation, or is or was serving at the request of such corporation as a director, officer, employee or agent of another
corporation or enterprise. The indemnity may include
expenses (including attorneys&#8217; fees), judgments, fines and amounts paid in settlement actually and reasonably incurred by
such person in connection with such action, suit or proceeding, provided such person acted in good faith and in a manner he reasonably
believed to be in or not opposed to the corporation&#8217;s best interests and, with respect to any criminal action or proceeding,
had no reasonable cause to believe that his conduct was unlawful. A Delaware corporation may indemnify any persons who are, were
or are threatened to be made, a party to any threatened, pending or completed action or suit by or in the right of the corporation
by reason of the fact that such person was a director, officer, employee or agent of such corporation, or is or was serving at
the request of such corporation as a director, officer, employee or agent of another corporation or enterprise. The indemnity
may include expenses (including attorneys&#8217; fees) actually and reasonably incurred by such person in connection with the
defense or settlement of such action or suit, provided such person acted in good faith and in a manner he reasonably believed
to be in or not opposed to the corporation&#8217;s best interests, provided that no indemnification is permitted without judicial
approval if the officer, director, employee or agent is adjudged to be liable to the corporation. Where an officer or director
is successful on the merits or otherwise in the defense of any action or claim referred to above, the corporation must indemnify
him against the expenses which such officer or director has actually and reasonably incurred in connection with such action or
claim.</FONT></P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt"><FONT STYLE="font-family: Times New Roman, Times, Serif"></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">The
Registrant&#8217;s certificate of incorporation, as amended (the &#8220;Certificate of Incorporation&#8221;), provides that it
shall indemnify and advance expenses to the fullest extent permitted by the DGCL, to each person who is or was one of the Registrant&#8217;s
directors or officers. The Certificate of Incorporation provides that upon request the Registrant shall advance expenses to, any
and all persons who is or was a party or is threatened to be made a party to any threatened, pending or completed action, suit,
proceeding or claim, whether civil, criminal, administrative or investigative, by reason of the fact that such person is or was
or has agreed to be a director or officer of the Registrant or while a director or officer is or was serving at the request of
the Registrant as a director, officer, partner, trustee, employee or agent of any corporation, partnership, joint venture, trust
or other enterprise, including service with respect to employee benefit plans, from and against any and all of the expenses, liabilities,
or other matters referred to in or covered by said section (including without limitation attorneys&#8217; fees and expenses);
provided, however, that if the DGCL requires an advancement of expenses incurred by an indemnitee in his capacity as a director
or officer, and not in any other capacity in which service was or is rendered by such indemnitee, including, without limitation,
service to an employee benefit plan, shall be made only upon delivery to the Registrant of an undertaking by or on behalf of such
indemnitee, to repay all amounts so advanced, if it shall ultimately be determined that such indemnitee is not entitled to be
indemnified for such expenses.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Section&nbsp;102(b)(7)
of the DGCL permits a corporation to include in its certificate of incorporation a provision eliminating or limiting the personal
liability of a director to the corporation or its stockholders for monetary damages for breach of fiduciary duty as a director,
provided that such provision shall not eliminate or limit the liability of a director (i)&nbsp;for any breach of the directors&#8217;
duty of loyalty to the corporation or its stockholders, (ii)&nbsp;for acts or omissions not in good faith or which involve intentional
misconduct or a knowing violation of law, (iii)&nbsp;under Section&nbsp;174 of the DGCL (relating to unlawful payment of dividends
and unlawful stock purchase and redemption) or (iv)&nbsp;for any transaction from which the director derived an improper personal
benefit. The Certificate of Incorporation includes such a provision.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Insofar
as indemnification for liabilities arising under the Securities Act of 1933, as amended (*the &#8220;Securities Act&#8221;), as
amended, may be permitted to directors, officers or persons controlling us pursuant to the foregoing provisions, the Registrant
has been informed that in the opinion of the Commission such indemnification is against public policy as expressed in the Securities
Act and is therefore unenforceable.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Section&nbsp;145
further authorizes a corporation to purchase and maintain insurance on behalf of any person who is or was a director, officer,
employee or agent of the corporation, or is or was serving at the request of the corporation as a director, officer, employee
or agent of another corporation or enterprise, against any liability asserted against him and incurred by him in any such capacity,
or arising out of his status as such, whether or not the corporation would otherwise have the power to indemnify him under Section&nbsp;145.
As permitted by Section&nbsp;145(g) of the DGCL, the Registrant&#8217;s directors and officers are covered by insurance policies
maintained by the Registrant against specified liabilities for actions taken in their capacities as such, including liabilities
under the Securities Act, subject to certain exclusions and exceptions.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 -11pt"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>ITEM
7.&#9;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B><U>Exemption from Registration Claimed</U>.</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&#9;Not
applicable.</FONT></P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 -11pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">ITEM
8.&#9;</FONT></P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif"><U>Exhibits</U>.</FONT></P>

<P STYLE="font: normal 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; font-weight: normal; font-style: normal">Reference
is made to the Exhibit Index on the page immediately preceding the exhibits for a list of exhibits filed as part of this Registration
Statement, which Exhibit Index is incorporated herein by reference.</FONT></P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 -11pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>ITEM
9.&#9;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B><U>Undertakings</U>. </B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">(a)&#9;The
undersigned Registrant hereby undertakes:</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 -11pt; text-align: justify; text-indent: 1in"><FONT STYLE="font-family: Times New Roman, Times, Serif">(1)&#9;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify; text-indent: 1.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">To
file, during any period in which offers or sales are being made, a post-effective amendment to the Registration Statement:</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify; text-indent: 1.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&#9;(i)&#9;to
include any prospectus required by Section 10(a)(3) of the Securities Act,</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt 1.5in; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&#9;(ii)&#9;to
reflect in the prospectus any facts or events arising after the effective date of the Registration Statement (or the most recent
post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set
forth in the Registration Statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if
the total dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high
end of the estimated maximum offering range may be reflected in the form of prospectus filed prospectus filed with the Commission
pursuant to Rule 424(b) if, in the aggregate, the changes in volume and price represent no more than a 20 percent change in the
maximum aggregate offering price set forth in the &#8220;Calculation of Registration fee&#8221; table in the effective Registration
Statement; and</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt 1.5in; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">&#9;(iii)&#9;to
include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement
or any material change to such information in the Registration Statement;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif"><I>provided,
however,</I> that paragraphs (1)(i) and (1)(ii) shall not apply if the information required to be included in a post-effective
amendment by those clauses is contained in periodic reports filed with or furnished to the Commission by the Registrant pursuant
to Section 13 or Section&nbsp;15(d) of the Exchange Act that are incorporated by reference into the Registration Statement;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 -11pt; text-align: justify; text-indent: 1in"><FONT STYLE="font-family: Times New Roman, Times, Serif">(2)&#9;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify; text-indent: 1.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">That,
for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be
a new Registration Statement relating to the securities offered therein, and the offering of such securities at that time shall
be deemed to be the initial bona fide offering thereof; and</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 -11pt; text-align: justify; text-indent: 1in"><FONT STYLE="font-family: Times New Roman, Times, Serif">(3)&#9;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify; text-indent: 1.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">To
remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at
the termination of the offering.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">(b)&#9;The
undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing
of the Registrant&#8217;s annual report pursuant to Section 13(a) or Section&nbsp;15(d) of the Exchange Act (and, where applicable,
each filing of an employee benefit plan&#8217;s annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated
by reference into the Registration Statement shall be deemed to be a new Registration Statement relating to the securities offered
therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">(c)&#9;Insofar
as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons
of the Registrant pursuant to the indemnification provisions summarized in Item 6 above, or otherwise, the Registrant has been
advised that in the opinion of the Securities and Exchange Commission such indemnification is against public policy as expressed
in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities
(other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant
in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection
with the securities being registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by
controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against
public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.&nbsp;</FONT>&nbsp;</P>


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<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">SIGNATURES</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: justify; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Pursuant
to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it
meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf
by the undersigned, thereunto duly authorized, in the city of New York, New York, on December 30, 2016</FONT>.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: justify; text-indent: 0.85in">&nbsp;</P>

<TABLE BORDER="0" CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif">
<TR>
     <TD STYLE="vertical-align: top">&nbsp;</TD>
     <TD COLSPAN="2" STYLE="vertical-align: top"><B>OHR PHARMACEUTICAL, INC.</B></TD>
</TR>
<TR>
     <TD STYLE="vertical-align: top">&nbsp;</TD>
     <TD COLSPAN="2" STYLE="vertical-align: top">&nbsp;</TD></TR>
<TR>
     <TD STYLE="vertical-align: top">&nbsp;</TD>
     <TD COLSPAN="2" STYLE="vertical-align: top">&nbsp;</TD></TR>
<TR>
     <TD STYLE="vertical-align: top; width: 53%">&nbsp;</TD>
     <TD STYLE="vertical-align: top; width: 4%">By:</TD>
     <TD STYLE="vertical-align: top; border-bottom: Black 1pt solid; width: 43%">&nbsp;/s/ Sam Backenroth</TD>
</TR>
<TR>
     <TD STYLE="vertical-align: top">&nbsp;</TD>
     <TD STYLE="vertical-align: top">&nbsp;</TD>
     <TD STYLE="vertical-align: top">Sam Backenroth</TD>
</TR>
<TR>
     <TD STYLE="vertical-align: top">&nbsp;</TD>
     <TD STYLE="vertical-align: top">&nbsp;</TD>
     <TD STYLE="vertical-align: top">Chief Financial Officer </TD></TR>
</TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">POWER
OF ATTORNEY</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: justify; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">KNOW
ALL PERSONS BY THESE PRESENTS, that each of Ira Greenstein, Orin Hirschman, June Almenoff and Thomas Riedhammer&nbsp;constitutes
and appoints Jason Slakter and Sam Backenroth, and each of them, as his true and lawful attorney-in-fact and agent, upon the action
of such appointee, with full power of substitution and resubstitution, to do any and all acts and things and execute, in the name
of the undersigned, any and all instruments which each of said attorneys-in-fact and agents may deem necessary or advisable in
order to enable Ohr Pharmaceutical, Inc. to comply with the Securities Act of 1933, as amended (the &#8220;Securities Act&#8221;),
and any requirements of the Securities and Exchange Commission (the &#8220;Commission&#8221;) in respect thereof, in connection
with the filing with the Commission of this Registration Statement on Form S-8 under the Securities Act, including specifically
but without limitation, power and authority to sign the name of the undersigned to such Registration Statement, and any amendments
to such Registration Statement (including post-effective amendments), and to file the same with all exhibits thereto and other
documents in connection therewith, with the Commission, to sign any and all applications, Registration Statements, notices or
other documents necessary or advisable to comply with applicable state securities laws, and to file the same, together with other
documents in connection therewith with the appropriate state securities authorities, granting unto each of said attorneys-in-fact
and agents full power and authority to do and to perform each and every act and thing requisite or necessary to be done in and
about the premises, as fully and to all intents and purposes as the undersigned might or could do in person, hereby ratifying
and confirming all that each of said attorneys-in-fact and agents may lawfully do or cause to be done by virtue hereof.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: justify; text-indent: 0.85in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Pursuant
to the requirements of the Securities Act, this Registration Statement has been signed by the following persons in the capacities
and on the dates indicated.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 11pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: bottom; font-family: Times New Roman, Times, Serif">
    <TD STYLE="width: 41%; padding-right: 0.7pt; padding-bottom: 3pt; padding-left: 0.7pt; text-decoration: underline; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B><U>Signature</U></B></FONT></TD>
    <TD STYLE="width: 37%; padding-right: 0.7pt; padding-bottom: 3pt; padding-left: 0.7pt; text-decoration: underline; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B><U>Title</U></B></FONT></TD>
    <TD STYLE="width: 22%; padding-right: 0.7pt; padding-bottom: 3pt; padding-left: 0.7pt; text-decoration: underline; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B><U>Date</U></B></FONT></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="font-family: Times New Roman, Times, Serif"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: justify; border-bottom: Black 0.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif">/s/
        Jason Slakter</FONT></P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0.2in 5pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Jason
        Slakter</FONT></P></TD>
    <TD STYLE="padding-top: 6pt; padding-right: 0; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Chief
    Executive Officer (Principal&nbsp;Executive Officer) and Director</FONT></TD>
    <TD STYLE="padding-top: 6pt; padding-right: 0; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">December
    30, 2016</FONT></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="font-family: Times New Roman, Times, Serif"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: justify; border-bottom: Black 0.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif">/s/
        Sam Backenroth</FONT></P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0.2in 5pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Sam
        Backenroth</FONT></P></TD>
    <TD STYLE="padding-top: 6pt; padding-right: 0; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Chief
    Financial Officer (Principal Financial&nbsp;and Accounting Officer)</FONT></TD>
    <TD STYLE="padding-top: 6pt; padding-right: 0; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">December
    30, 2016</FONT></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="font-family: Times New Roman, Times, Serif"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: justify; border-bottom: Black 0.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif">/s/
        Ira Greenstein</FONT></P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0.2in 5pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Ira
        Greenstein</FONT></P></TD>
    <TD STYLE="padding-top: 6pt; padding-right: 0; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</FONT></TD>
    <TD STYLE="padding-top: 6pt; padding-right: 0; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">December
    30, 2016</FONT></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="font-family: Times New Roman, Times, Serif"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: justify; border-bottom: Black 0.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif">/s/
        Orin Hirschman</FONT></P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0.2in 5pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Orin
        Hirschman</FONT></P></TD>
    <TD STYLE="padding-top: 6pt; padding-right: 0; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</FONT></TD>
    <TD STYLE="padding-top: 6pt; padding-right: 0; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">December
    30, 2016</FONT></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="font-family: Times New Roman, Times, Serif"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: justify; border-bottom: Black 0.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif">/s/
        June Almenoff</FONT></P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0.2in 5pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">June
        Almenoff</FONT></P></TD>
    <TD STYLE="padding-top: 6pt; padding-right: 0; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</FONT></TD>
    <TD STYLE="padding-top: 6pt; padding-right: 0; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">December
    30, 2016</FONT></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="font-family: Times New Roman, Times, Serif"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: justify; border-bottom: Black 0.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif">/s/
        Thomas Riedhammer</FONT></P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0.2in 5pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Thomas
        Riedhammer</FONT></P></TD>
    <TD STYLE="padding-top: 6pt; padding-right: 0; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</FONT></TD>
    <TD STYLE="padding-top: 6pt; padding-right: 0; text-align: center; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">December
    30, 2016</FONT></TD></TR>
</TABLE>

<P STYLE="margin-top: 0; margin-bottom: 0">&nbsp;</P>

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<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">INDEX
TO EXHIBITS</FONT></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 11pt Times New Roman, Times, Serif; border-collapse: collapse">
<TR STYLE="vertical-align: bottom; font-family: Times New Roman, Times, Serif">
    <TD STYLE="width: 1in; padding-right: 5.4pt; padding-left: 5.4pt; font-family: Times New Roman, Times, Serif"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: center; border-bottom: Black 1pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>Exhibit</B><BR>
        <B>Number</B></FONT></P></TD>
    <TD STYLE="width: 0.3in">&nbsp;</TD>
    <TD STYLE="border-bottom: Black 1pt solid; padding-top: 12pt; padding-right: 5.4pt; padding-left: 5.4pt; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Description</B></FONT></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="padding-top: 12pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">4.1(a)</FONT></TD>
    <TD>&nbsp;</TD>
    <TD STYLE="padding-top: 12pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: left; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Form
    of Class J Common Stock Purchase Warrant issued on December 16, <FONT STYLE="background-color: white">2011</FONT>
    (1)</FONT></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="padding-top: 12pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">4.1(b)</FONT></TD>
    <TD>&nbsp;</TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; font-family: Times New Roman, Times, Serif; text-align: left; vertical-align: bottom"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"></FONT></P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Amendment,
        dated March 11, 2014, to Class J Common Stock Purchase Warrants (2)</FONT></P></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="padding-top: 12pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right; font: normal 10pt Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; font-weight: normal; font-style: normal">4.2</FONT></TD>
    <TD STYLE="font: normal 10pt Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; font-weight: normal; font-style: normal">&nbsp;</FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; font: normal 10pt Times New Roman, Times, Serif; text-align: left; vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; font-weight: normal; font-style: normal">Form
    of Series A Warrant (3)</FONT></TD></TR>
<TR STYLE="vertical-align: top; font: normal 10pt Times New Roman, Times, Serif">
    <TD STYLE="padding-top: 12pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right; font: normal 10pt Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; font-weight: normal; font-style: normal">4.3</FONT></TD>
    <TD STYLE="font: normal 10pt Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; font-weight: normal; font-style: normal">&nbsp;</FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; font: normal 10pt Times New Roman, Times, Serif; text-align: left; vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; font-weight: normal; font-style: normal">Form
    of Series B Warrant (3)</FONT></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="padding-top: 12pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.1</FONT></TD>
    <TD>&nbsp;</TD>
    <TD STYLE="padding-top: 12pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: left; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><A HREF="ex5-1.htm">Opinion of Troutman Sanders LLP</A></FONT></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="padding-top: 12pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">23.1</FONT></TD>
    <TD>&nbsp;</TD>
    <TD STYLE="padding-top: 12pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: left; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><A HREF="ex23-1.htm">Consent of MaloneBailey, LLP</A></FONT></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="padding-top: 12pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">23.2</FONT></TD>
    <TD>&nbsp;</TD>
    <TD STYLE="padding-top: 12pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: left; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Consent
    of Troutman Sanders LLP (included in Exhibit 5.1)</FONT></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="padding-top: 12pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">24.1</FONT></TD>
    <TD>&nbsp;</TD>
    <TD STYLE="padding-top: 12pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: left; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Power
    of Attorney (included on signature page)</FONT></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="padding-top: 12pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">99.1</FONT></TD>
    <TD>&nbsp;</TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; font-family: Times New Roman, Times, Serif"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">Ohr
        Pharmaceutical, Inc. 2014 Stock Incentive Plan (4)</FONT></P></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="padding-top: 12pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">99.2</FONT></TD>
    <TD>&nbsp;</TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; font-family: Times New Roman, Times, Serif"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">Amendment
        to Ohr Pharmaceutical, Inc. 2014 Stock Incentive Plan (5)</FONT></P></TD></TR>
<TR STYLE="vertical-align: top; font-family: Times New Roman, Times, Serif">
    <TD STYLE="padding-top: 12pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">99.3</FONT></TD>
    <TD>&nbsp;</TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; font-family: Times New Roman, Times, Serif"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">Ohr
        Pharmaceutical, Inc. 2016 Consolidated Stock Incentive Plan (6)</FONT></P></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">_________________________________</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">(1) Incorporated
by reference to the Ohr Pharmaceutical, Inc. Current Report on Form 8-K (File No. <FONT STYLE="background-color: white">001-35963</FONT>),
filed on December 20, 2011.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">(2) Incorporated
by reference to the Ohr Pharmaceutical, Inc. Current Report on Form 8-K (File No. <FONT STYLE="background-color: white">001-35963</FONT>),
filed on March 14, 2014.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">(3)
Incorporated by reference to the Ohr Pharmaceutical, Inc. Current Report on Form 8-K (File No. 001-35963), filed
on December 8, 2016. &nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">(4) Incorporated
by reference to the Ohr Pharmaceutical, Inc. Current Report on Form 8-K (File No. <FONT STYLE="background-color: white">001-35963</FONT>),
filed on April 14, 2014.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">(5) Incorporated
by reference to the Ohr Pharmaceutical, Inc. Annual Report on Form 10-K (File No. <FONT STYLE="background-color: white">001-35963</FONT>),
for the fiscal year ended September 30, 2015, filed on December 14, 2015.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">(6) Incorporated
by reference to the Ohr Pharmaceutical, Inc. Current Report on Form 8-K (File No. <FONT STYLE="background-color: white">001-35963</FONT>),
filed on March 21, 2016.</FONT></P>



<P STYLE="margin: 0; font-family: Times New Roman, Times, Serif">&nbsp;</P>

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As
filed with the Securities and Exchange Commission on December 30, 2016
Registration
No. 333-
UNITED
STATES SECURITIES AND EXCHANGE COMMISSION
Washington,
D.C. 20549
________________
FORM
S-8
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
________________
OHR
PHARMACEUTICAL, INC.
(Exact
name of Registrant as specified in its charter)
Delaware
46-5622433
(State
    or other jurisdiction of
incorporation or organization)
(I.R.S.
    Employer
Identification No.)
800
    Third Ave, 11
th
Floor
New York, NY
10977
(Address
    of Principal Executive Offices)
(Zip
    Code)
________________
Ohr
Pharmaceutical, Inc. 2014 Stock Incentive Plan
Ohr
Pharmaceutical, Inc. 2016 Consolidated Stock Incentive Plan
(Full
title of the plans)
Sam
Backenroth
Chief Financial Officer
Ohr Pharmaceutical, Inc.
800 Third Avenue, 11th Floor
New York, New York 10022
(Name and address of agent for service)
(212)
682-8452
(
Telephone
number, including area code, of agent for service)
________________
Copies
of all correspondence to:
Aurora
Cassirer
, Esq.
Joseph Walsh, Esq.
Troutman Sanders LLP
875 Third Avenue
New
York, New York 10022
(212) 704-6000
________________
Indicate
by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer or a smaller
reporting company. See definitions of "large accelerated filer," "accelerated filer," and "smaller
reporting company" in Rule 12b-2 of the Exchange Act.
Large accelerated filer
☐
Accelerated filer
☒
Non-accelerated filer
☐ (Do not check if a smaller reporting company)
Smaller reporting company
☐
CALCULATION
OF REGISTRATION FEE
Title
    of
Securities to be Registered
Amount
    to be Registered
(1)
Proposed
Maximum
Offering Price
Per Share
Proposed
Maximum
Aggregate
Offering Price
Amount
    of
Registration Fee
Common
    Stock, $0.0001 par value per share
2,179,000
(2)
$7.73
(3)
$16,843,670
$1,952
(3)
Common
    Stock, $0.0001 par value per share
120,550
(4)
$7.93
(5)
$955,962
$111
(5)
Common
    Stock, $0.0001 par value per share
80,000
(6)
$3.23
(7)
$258,400
$30
(7)
Common
    Stock, $0.0001 par value per share
2,681,275
(8)
$1.625
(9)
$4,357,072
$505
(9)
Total
5,060,825
$22,415,104
$2,598
(1)
Pursuant
                                         to Rule 416(a) under the Securities Act of 1933, as amended (the "Securities Act"),
                                         this Registration Statement also covers an indeterminate number of additional shares
                                         common stock, $0.0001 par value per share (the "Common Stock"), of the Registrant,
                                         which may be offered and issued to prevent dilution resulting from adjustments as a result
                                         of stock dividends, stock splits, reverse stock splits, recapitalizations, reclassifications,
                                         mergers, split-ups, reorganizations, consolidations and other capital adjustments.
(2)
Represents
                                         shares of Common Stock issuable pursuant to outstanding but unexercised stock options
                                         previously granted under the Ohr Pharmaceutical, Inc. 2014 Stock Incentive Plan (the
                                         "2014 Plan").
(3)
Estimated
                                         solely for the purpose of determining the amount of the registration fee in accordance
                                         with Rule 457(h) under the Securities Act, based upon the weighted average exercise price
                                         of $7.73 of the outstanding but unexercised stock options previously granted under the
                                         2014 Plan.
(4)
Represents
                                         shares of Common Stock issuable pursuant to outstanding but unexercised warrants previously
                                         granted under the 2014 Plan.
(5)
Estimated
                                         solely for the purpose of determining the amount of the registration fee in accordance
                                         with Rule 457(h) under the Securities Act, based upon the weighted average exercise price
                                         of $7.93 of the outstanding but unexercised warrants previously granted under the 2014
                                         Plan.
(6)
Represents
                                         shares of Common Stock issuable pursuant to outstanding but unexercised stock options
                                         previously granted under the Ohr Pharmaceutical, Inc. 2016 Consolidated Stock Incentive
                                         Plan (the "2016 Plan").
(7)
Estimated
                                         solely for the purpose of determining the amount of the registration fee in accordance
                                         with Rule 457(h) under the Securities Act, based upon the weighted average exercise price
                                         of $3.23 of the outstanding but unexercised stock options previously granted under the
                                         2016 Plan.
(8)
Represents
                                         shares of Common Stock issuable pursuant to awards to be issued under the Ohr Pharmaceutical,
                                         Inc. 2016 Plan.
(9)
Estimated
                                                                                                                                                                                                                    solely for the purpose of calculating the registration fee and computed in accordance
                                                                                                                                                                                                                    with Rule 457(c) and (h) under the Securities Act using the average of the high
                                                                                                                                                                                                                    and low sale prices of the Common Stock as reported on The NASDAQ Capital Market on December 27, 2016, which was $1.625 per
                                                                                                                                                                                                                    share.
PART
I
INFORMATION
REQUIRED IN THE SECTION 10(a) PROSPECTUS
ITEM
1.
Plan Information
.
Not
required to be filed with this Registration Statement.
ITEM
2.
Registrant Information and Employee Plan Annual Information
.
Not
required to be filed with this Registration Statement.
PART
II
INFORMATION
REQUIRED IN THE REGISTRATION STATEMENT
ITEM
3.
Incorporation of Documents by Reference
.
The
Registrant hereby incorporates by reference into this Registration Statement the following documents previously filed by the Registrant
with the Securities and Exchange Commission (the "Commission"):
●
the
                                         Registrant's Annual Report on Form 10-K (No.
001-35963
)
                                         for the fiscal year ended September 30, 2016, filed with the Commission on December 22,
                                         2016;
●
the
                                                                                                                                                                                                                Registrant's Current Report on Form 8-K (No.
001-35963
)
                                                                                                                                                                                                                filed with the Commission on December 8, 2016; and
●
The
                                         description of the Registrant's common stock
,
contained in the Registrant's Registration Statement on Form
8-A
(File No. 001-35963), filed by the Registrant with the Commission on June
                                         11, 2013, including any amendments or reports filed for the purpose of updating such
                                         description.
All
documents that the Registrant subsequently filed pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Securities and Exchange
Act of 1934, as amended, prior to the filing of a post-effective amendment to this Registration Statement which indicates that
all of the shares of common stock of the Registrant offered have been sold or which deregisters all of such shares of common stock
then remaining unsold, shall be deemed to be incorporated by reference in this Registration Statement and to be a part hereof
from the date of the filing of such documents.
Any
statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified
or superseded to the extent that a statement contained herein or in any other subsequently filed document which also is or is
deemed to be incorporated by reference herein modifies or supersedes such statement. Any such statement so modified or superseded
shall not be deemed, except as so modified or superseded, to constitute a part of this Registration Statement.
Notwithstanding
the above, information that is "furnished to" the Commission shall not be deemed "filed with" the Commission
and shall not be deemed incorporated by reference into this Registration Statement.
ITEM
4.
Description of Securities
.
Not
applicable.
ITEM
5.
Interests of Named Experts and Counsel
.
Not
applicable.
ITEM
6.
Indemnification of Directors and Officers
.
The
Registrant is incorporated under the laws of the State of Delaware. Section 145 ("Section 145") of the General
Corporation Law of the State of Delaware, as the same exists or may hereafter be amended (the "DGCL"), provides that
a Delaware corporation may indemnify any persons who were, are or are threatened to be made, parties to any threatened, pending
or completed action, suit or proceeding, whether civil, criminal, administrative or investigative (other than an action by or
in the right of such corporation), by reason of the fact that such person is or was an officer, director, employee or agent of
such corporation, or is or was serving at the request of such corporation as a director, officer, employee or agent of another
corporation or enterprise. The indemnity may include
expenses (including attorneys' fees), judgments, fines and amounts paid in settlement actually and reasonably incurred by
such person in connection with such action, suit or proceeding, provided such person acted in good faith and in a manner he reasonably
believed to be in or not opposed to the corporation's best interests and, with respect to any criminal action or proceeding,
had no reasonable cause to believe that his conduct was unlawful. A Delaware corporation may indemnify any persons who are, were
or are threatened to be made, a party to any threatened, pending or completed action or suit by or in the right of the corporation
by reason of the fact that such person was a director, officer, employee or agent of such corporation, or is or was serving at
the request of such corporation as a director, officer, employee or agent of another corporation or enterprise. The indemnity
may include expenses (including attorneys' fees) actually and reasonably incurred by such person in connection with the
defense or settlement of such action or suit, provided such person acted in good faith and in a manner he reasonably believed
to be in or not opposed to the corporation's best interests, provided that no indemnification is permitted without judicial
approval if the officer, director, employee or agent is adjudged to be liable to the corporation. Where an officer or director
is successful on the merits or otherwise in the defense of any action or claim referred to above, the corporation must indemnify
him against the expenses which such officer or director has actually and reasonably incurred in connection with such action or
claim.
The
Registrant's certificate of incorporation, as amended (the "Certificate of Incorporation"), provides that it
shall indemnify and advance expenses to the fullest extent permitted by the DGCL, to each person who is or was one of the Registrant's
directors or officers. The Certificate of Incorporation provides that upon request the Registrant shall advance expenses to, any
and all persons who is or was a party or is threatened to be made a party to any threatened, pending or completed action, suit,
proceeding or claim, whether civil, criminal, administrative or investigative, by reason of the fact that such person is or was
or has agreed to be a director or officer of the Registrant or while a director or officer is or was serving at the request of
the Registrant as a director, officer, partner, trustee, employee or agent of any corporation, partnership, joint venture, trust
or other enterprise, including service with respect to employee benefit plans, from and against any and all of the expenses, liabilities,
or other matters referred to in or covered by said section (including without limitation attorneys' fees and expenses);
provided, however, that if the DGCL requires an advancement of expenses incurred by an indemnitee in his capacity as a director
or officer, and not in any other capacity in which service was or is rendered by such indemnitee, including, without limitation,
service to an employee benefit plan, shall be made only upon delivery to the Registrant of an undertaking by or on behalf of such
indemnitee, to repay all amounts so advanced, if it shall ultimately be determined that such indemnitee is not entitled to be
indemnified for such expenses.
Section 102(b)(7)
of the DGCL permits a corporation to include in its certificate of incorporation a provision eliminating or limiting the personal
liability of a director to the corporation or its stockholders for monetary damages for breach of fiduciary duty as a director,
provided that such provision shall not eliminate or limit the liability of a director (i) for any breach of the directors'
duty of loyalty to the corporation or its stockholders, (ii) for acts or omissions not in good faith or which involve intentional
misconduct or a knowing violation of law, (iii) under Section 174 of the DGCL (relating to unlawful payment of dividends
and unlawful stock purchase and redemption) or (iv) for any transaction from which the director derived an improper personal
benefit. The Certificate of Incorporation includes such a provision.
Insofar
as indemnification for liabilities arising under the Securities Act of 1933, as amended (*the "Securities Act"), as
amended, may be permitted to directors, officers or persons controlling us pursuant to the foregoing provisions, the Registrant
has been informed that in the opinion of the Commission such indemnification is against public policy as expressed in the Securities
Act and is therefore unenforceable.
Section 145
further authorizes a corporation to purchase and maintain insurance on behalf of any person who is or was a director, officer,
employee or agent of the corporation, or is or was serving at the request of the corporation as a director, officer, employee
or agent of another corporation or enterprise, against any liability asserted against him and incurred by him in any such capacity,
or arising out of his status as such, whether or not the corporation would otherwise have the power to indemnify him under Section 145.
As permitted by Section 145(g) of the DGCL, the Registrant's directors and officers are covered by insurance policies
maintained by the Registrant against specified liabilities for actions taken in their capacities as such, including liabilities
under the Securities Act, subject to certain exclusions and exceptions.
ITEM
7.
Exemption from Registration Claimed
.
Not
applicable.
ITEM
8.
Exhibits
.
Reference
is made to the Exhibit Index on the page immediately preceding the exhibits for a list of exhibits filed as part of this Registration
Statement, which Exhibit Index is incorporated herein by reference.
ITEM
9.
Undertakings
.
(a)	The
undersigned Registrant hereby undertakes:
(1)
To
file, during any period in which offers or sales are being made, a post-effective amendment to the Registration Statement:
(i)	to
include any prospectus required by Section 10(a)(3) of the Securities Act,
(ii)	to
reflect in the prospectus any facts or events arising after the effective date of the Registration Statement (or the most recent
post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set
forth in the Registration Statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if
the total dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high
end of the estimated maximum offering range may be reflected in the form of prospectus filed prospectus filed with the Commission
pursuant to Rule 424(b) if, in the aggregate, the changes in volume and price represent no more than a 20 percent change in the
maximum aggregate offering price set forth in the "Calculation of Registration fee" table in the effective Registration
Statement; and
(iii)	to
include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement
or any material change to such information in the Registration Statement;
provided,
however,
that paragraphs (1)(i) and (1)(ii) shall not apply if the information required to be included in a post-effective
amendment by those clauses is contained in periodic reports filed with or furnished to the Commission by the Registrant pursuant
to Section 13 or Section 15(d) of the Exchange Act that are incorporated by reference into the Registration Statement;
(2)
That,
for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be
a new Registration Statement relating to the securities offered therein, and the offering of such securities at that time shall
be deemed to be the initial bona fide offering thereof; and
(3)
To
remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at
the termination of the offering.
(b)	The
undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing
of the Registrant's annual report pursuant to Section 13(a) or Section 15(d) of the Exchange Act (and, where applicable,
each filing of an employee benefit plan's annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated
by reference into the Registration Statement shall be deemed to be a new Registration Statement relating to the securities offered
therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.
(c)	Insofar
as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons
of the Registrant pursuant to the indemnification provisions summarized in Item 6 above, or otherwise, the Registrant has been
advised that in the opinion of the Securities and Exchange Commission such indemnification is against public policy as expressed
in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities
(other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant
in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection
with the securities being registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by
controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against
public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.
SIGNATURES
Pursuant
to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it
meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf
by the undersigned, thereunto duly authorized, in the city of New York, New York, on December 30, 2016
.
OHR PHARMACEUTICAL, INC.
By:
/s/ Sam Backenroth
Sam Backenroth
Chief Financial Officer
POWER
OF ATTORNEY
KNOW
ALL PERSONS BY THESE PRESENTS, that each of Ira Greenstein, Orin Hirschman, June Almenoff and Thomas Riedhammer constitutes
and appoints Jason Slakter and Sam Backenroth, and each of them, as his true and lawful attorney-in-fact and agent, upon the action
of such appointee, with full power of substitution and resubstitution, to do any and all acts and things and execute, in the name
of the undersigned, any and all instruments which each of said attorneys-in-fact and agents may deem necessary or advisable in
order to enable Ohr Pharmaceutical, Inc. to comply with the Securities Act of 1933, as amended (the "Securities Act"),
and any requirements of the Securities and Exchange Commission (the "Commission") in respect thereof, in connection
with the filing with the Commission of this Registration Statement on Form S-8 under the Securities Act, including specifically
but without limitation, power and authority to sign the name of the undersigned to such Registration Statement, and any amendments
to such Registration Statement (including post-effective amendments), and to file the same with all exhibits thereto and other
documents in connection therewith, with the Commission, to sign any and all applications, Registration Statements, notices or
other documents necessary or advisable to comply with applicable state securities laws, and to file the same, together with other
documents in connection therewith with the appropriate state securities authorities, granting unto each of said attorneys-in-fact
and agents full power and authority to do and to perform each and every act and thing requisite or necessary to be done in and
about the premises, as fully and to all intents and purposes as the undersigned might or could do in person, hereby ratifying
and confirming all that each of said attorneys-in-fact and agents may lawfully do or cause to be done by virtue hereof.
Pursuant
to the requirements of the Securities Act, this Registration Statement has been signed by the following persons in the capacities
and on the dates indicated.
Signature
Title
Date
/s/
        Jason Slakter
Jason
        Slakter
Chief
    Executive Officer (Principal Executive Officer) and Director
December
    30, 2016
/s/
        Sam Backenroth
Sam
        Backenroth
Chief
    Financial Officer (Principal Financial and Accounting Officer)
December
    30, 2016
/s/
        Ira Greenstein
Ira
        Greenstein
Director
December
    30, 2016
/s/
        Orin Hirschman
Orin
        Hirschman
Director
December
    30, 2016
/s/
        June Almenoff
June
        Almenoff
Director
December
    30, 2016
/s/
        Thomas Riedhammer
Thomas
        Riedhammer
Director
December
    30, 2016
INDEX
TO EXHIBITS
Exhibit
Number
Description
4.1(a)
Form
    of Class J Common Stock Purchase Warrant issued on December 16,
2011
(1)
4.1(b)
Amendment,
        dated March 11, 2014, to Class J Common Stock Purchase Warrants (2)
4.2
Form
    of Series A Warrant (3)
4.3
Form
    of Series B Warrant (3)
5.1
Opinion of Troutman Sanders LLP
23.1
Consent of MaloneBailey, LLP
23.2
Consent
    of Troutman Sanders LLP (included in Exhibit 5.1)
24.1
Power
    of Attorney (included on signature page)
99.1
Ohr
        Pharmaceutical, Inc. 2014 Stock Incentive Plan (4)
99.2
Amendment
        to Ohr Pharmaceutical, Inc. 2014 Stock Incentive Plan (5)
99.3
Ohr
        Pharmaceutical, Inc. 2016 Consolidated Stock Incentive Plan (6)
_________________________________
(1) Incorporated
by reference to the Ohr Pharmaceutical, Inc. Current Report on Form 8-K (File No.
001-35963
),
filed on December 20, 2011.
(2) Incorporated
by reference to the Ohr Pharmaceutical, Inc. Current Report on Form 8-K (File No.
001-35963
),
filed on March 14, 2014.
(3)
Incorporated by reference to the Ohr Pharmaceutical, Inc. Current Report on Form 8-K (File No. 001-35963), filed
on December 8, 2016.
(4) Incorporated
by reference to the Ohr Pharmaceutical, Inc. Current Report on Form 8-K (File No.
001-35963
),
filed on April 14, 2014.
(5) Incorporated
by reference to the Ohr Pharmaceutical, Inc. Annual Report on Form 10-K (File No.
001-35963
),
for the fiscal year ended September 30, 2015, filed on December 14, 2015.
(6) Incorporated
by reference to the Ohr Pharmaceutical, Inc. Current Report on Form 8-K (File No.
001-35963
),
filed on March 21, 2016.