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<TITLE>Illumina, Inc. Form S-8</TITLE>
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<H5 align="left"><A HREF="#toc">Table of Contents</A></H5><P>

<P align="center"><FONT size="2">As filed with the Securities and Exchange Commission on September&nbsp;6, 2001</FONT>

<DIV align="right"><FONT size="2">Registration No. _________</FONT></DIV>

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<DIV align="center"><FONT size="2"><B>SECURITIES AND EXCHANGE COMMISSION</B><BR>
Washington, D.C. 20549<BR>
<BR>
<BR>
<B>FORM S-8<BR>
REGISTRATION STATEMENT</B><BR>
<I>Under<BR>
The Securities Act of 1933</I><BR>
<B>__________</B></FONT></DIV>

<P align="center"><FONT size="2"><B>ILLUMINA, INC.</B><BR>
(Exact name of registrant as specified in its charter)</FONT>

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<TABLE cellspacing="0" border="0" cellpadding="0" width="100%">
<TR valign="bottom">
        <TD width="47%">&nbsp;</TD>
        <TD width="6%">&nbsp;</TD>
        <TD width="47%">&nbsp;</TD>
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<TR valign="bottom">
        <TD align="center" valign="top"><FONT size="2"><B>Delaware</B><BR>
(State or other jurisdiction<BR>
of incorporation or organization)</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="center" valign="top"><FONT size="2">
<B>33-0804655</B><BR>
(IRS Employer Identification No.)</FONT></TD>
</TR>
</TABLE>
</CENTER>
<P align="center"><FONT size="2"><B>9390 Towne Centre Drive, Suite&nbsp;200<BR>
San Diego, California 92121</B><BR>
(Address of principal executive offices) (Zip Code)<BR>
<B>__________</B></FONT>

<P align="center"><FONT size="2"><B>2000 Stock Plan<BR>
2000 Employee Stock Purchase Plan</B><BR>
(Full title of the Plan)</FONT>

<P align="center"><FONT size="2"><B>____________</B></FONT>

<P align="center"><FONT size="2"><B>Jay T. Flatley<BR>
Chief Executive Officer and President<BR>
Illumina, Inc.<BR>
9390 Towne Centre Drive, Suite&nbsp;200, San Diego, California, 92121</B><BR>
(Name and address of agent for service)<BR>
<B>(858)&nbsp;587-4290</B><BR>
(Telephone number, including area code, of agent for service)</FONT>

<P align="center"><FONT size="2"><B>___________</B></FONT>


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<TABLE cellspacing="0" border="0" cellpadding="0" width="100%">
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        <TD width="38%">&nbsp;</TD>
        <TD width="3%">&nbsp;</TD>
        <TD width="10%">&nbsp;</TD>
        <TD width="1%">&nbsp;</TD>
        <TD width="10%">&nbsp;</TD>
        <TD width="3%">&nbsp;</TD>
        <TD width="1%">&nbsp;</TD>
        <TD width="1%">&nbsp;</TD>
        <TD width="2%">&nbsp;</TD>
        <TD width="3%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="1%">&nbsp;</TD>
        <TD width="6%">&nbsp;</TD>
        <TD width="3%">&nbsp;</TD>
        <TD width="6%">&nbsp;</TD>
        <TD width="1%">&nbsp;</TD>
        <TD width="6%">&nbsp;</TD>
</TR>

<TR valign="bottom">
        <TD nowrap align="center" colspan="17"><FONT size="2"><B>CALCULATION OF REGISTRATION FEE</B></FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center" colspan="17"><FONT size="1"><HR SIZE="4" NOSHADE></FONT></TD>
</TR>

<TR valign="bottom">
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1">Offering</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1">Amount of</FONT></TD>
</TR>
<TR valign="bottom">
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1">Amount to be</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1">Price</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1">Aggregate</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1">Registration</FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><FONT size="1">Title of Securities to be Registered</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1">Registered (1)</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1">per Share</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1">Offering Price</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center" colspan="3"><FONT size="1">Fee</FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><HR size="1" noshade></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD colspan="3"><HR size="1" noshade></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD colspan="3"><HR size="1" noshade></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD colspan="3"><HR size="1" noshade></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD colspan="3"><HR size="1" noshade></TD>
</TR>
<TR valign="bottom">
        <TD><DIV style="margin-left:10px; text-indent:-10px"><FONT size="2">2000 Stock Plan</FONT></DIV></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom" bgcolor="#eeeeee">
        <TD><DIV style="margin-left:10px; text-indent:-10px"><FONT size="2">Common Stock, $0.01 par value</FONT></DIV></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3" align="center"><FONT size="2">4,149,460 shares (2)</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="right"><FONT size="2">$</FONT></TD>
        <TD align="right"><FONT size="2">8.65</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="right"><FONT size="2">$</FONT></TD>
        <TD align="right"><FONT size="2">12,975,000</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD nowrap align="right"><FONT size="2">$</FONT></TD>
        <TD align="right"><FONT size="2">3,243.75</FONT></TD>
        <TD nowrap><FONT size="2">(3)</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD><DIV style="margin-left:10px; text-indent:-10px"><FONT size="2">2000 Employee Stock Purchase Plan</FONT></DIV></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom" bgcolor="#eeeeee">
        <TD><DIV style="margin-left:10px; text-indent:-10px"><FONT size="2">Common Stock, $0.01 par value</FONT></DIV></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3" align="center"><FONT size="2">958,946 shares (4)</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="right"><FONT size="2">$</FONT></TD>
        <TD align="right"><FONT size="2">8.65</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="right"><FONT size="2">$</FONT></TD>
        <TD align="right"><FONT size="2">8,294,883</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD nowrap align="right"><FONT size="2">$</FONT></TD>
        <TD align="right"><FONT size="2">2,073.72</FONT></TD>
        <TD nowrap><FONT size="2">(5)</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD nowrap align="center" colspan="17"><FONT size="1"><HR SIZE="4" NOSHADE></FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="RIGHT" colspan="12"><FONT size="2">Aggregate Registration Fee</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="right"><FONT size="2">$</FONT></TD>
        <TD align="right"><FONT size="2">5,317.47</FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center" colspan="17"><FONT size="1"><HR SIZE="4" NOSHADE></FONT></TD>
</TR>
</TABLE>
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<P>
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR valign="top">
   <TD width="1%" align="right" nowrap><FONT size="2">(1)</FONT></TD>
   <TD width="1%" nowrap><FONT size="2">&nbsp;&nbsp;</FONT></TD>
   <TD width="98%"><FONT size="2">This Registration Statement shall also cover any additional shares of
Common Stock, par value $0.01 (the &#147;Common Stock&#148;), of Illumina, Inc. (the
&#147;Registrant&#148;) which become issuable under the Illumina, Inc. 2000 Stock
Plan (the &#147;2000 Option Plan&#148;) and the Illumina, Inc. 2000 Employee Stock
Purchase Plan (the &#147;Purchase Plan&#148;) by reason of any stock dividend, stock
split, recapitalization or other similar transaction effected without the
Registrant&#146;s receipt of consideration which results in an increase in the
number of outstanding shares of Common Stock.</FONT></TD>
</TR>
</TABLE>
<P align="center"><FONT size="2">&nbsp;
</FONT>

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<H5 align="left"><A HREF="#toc">Table of Contents</A></H5><P>



<P>
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR valign="top">
   <TD width="1%" align="right" nowrap><FONT size="2">(2)</FONT></TD>
   <TD width="1%" nowrap><FONT size="2">&nbsp;&nbsp;</FONT></TD>
   <TD width="98%"><FONT size="2">1,500,000 shares of the 4,149,460 shares of Common Stock subject to this
Registration Statement were available for issuance under the 2000 Option
Plan effective as of January&nbsp;2, 2001. The remaining 2,649,460 shares of
the 4,149,460 shares of Common Stock subject to this Registration
Statement were transferred to the 2000 Option Plan from the Registrant&#146;s
1998 Incentive Stock Plan (the &#147;1998 Option Plan&#148;). Such shares were
previously registered on Form&nbsp;S-8 Registration Statement No.&nbsp;333-42866
filed on August&nbsp;2, 2000 (the &#147;2000 Registration Statement&#148;).</FONT></TD>
</TR>
<TR>
        <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR valign="top">
   <TD width="1%" align="right" nowrap><FONT size="2">(3)</FONT></TD>
   <TD width="1%" nowrap><FONT size="2">&nbsp;&nbsp;</FONT></TD>
   <TD width="98%"><FONT size="2">The Registration Fee with respect to the 2000 Option Plan is based solely
on 1,500,000 shares of Common Stock newly available for issuance under the
2000 Option Plan and is calculated solely for purposes of this offering
under Rule&nbsp;457(h) of the Securities Act of 1933 on the basis of the
average of the high and low selling price per share of Common Stock on
August&nbsp;31, 2001, as reported by the Nasdaq National Market. The
applicable filing fees for the remaining 2,649,460 shares transferred from
the 2000 Option Plan from the 1998 Option Plan were paid in connection
with the 2000 Registration Statement.</FONT></TD>
</TR>
<TR>
        <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR valign="top">
   <TD width="1%" align="right" nowrap><FONT size="2">(4)</FONT></TD>
   <TD width="1%" nowrap><FONT size="2">&nbsp;&nbsp;</FONT></TD>
   <TD width="98%"><FONT size="2">958,946 shares of Common Stock were available for issuance under the
Purchase Plan effective as of January&nbsp;2, 2001.</FONT></TD>
</TR>
<TR>
        <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR valign="top">
   <TD width="1%" align="right" nowrap><FONT size="2">(5)</FONT></TD>
   <TD width="1%" nowrap><FONT size="2">&nbsp;&nbsp;</FONT></TD>
   <TD width="98%"><FONT size="2">The Registration Fee with respect to the Purchase Plan is based solely on
958,946 shares of Common Stock newly available for issuance under the
Purchase Plan and is calculated solely for purposes of this offering under
Rule&nbsp;457(h) of the Securities Act of 1933 on the basis of the average of
the high and low selling price per share of Common Stock on August&nbsp;31,
2001, as reported by the Nasdaq National Market.</FONT></TD>
</TR>
</TABLE>
<P align="center"><FONT size="2">&nbsp;
</FONT>

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<!-- TOC -->
<A name="toc"><DIV align="CENTER"><U><B>TABLE OF CONTENTS</B></U></DIV></A>

<P><CENTER>
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<TR><TD colspan="9"><A HREF="#000">PART II Information Required in the Registration Statement</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#001">Item&nbsp;3. Information Incorporated by Reference.</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#002">Item&nbsp;4. Description of Securities.</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#003">Item&nbsp;5. Interests of Named Experts and Counsel.</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#004">Item&nbsp;6. Indemnification of Directors and Officers.</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#005">Item&nbsp;7. Exemption From Registration Claimed.</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#006">Item&nbsp;8. Exhibits.</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#007">Item&nbsp;9. Undertakings.</A></TD></TR>
<TR><TD colspan="9"><A HREF="#008">SIGNATURES</A></TD></TR>
<TR><TD colspan="9"><A HREF="#009">POWER OF ATTORNEY</A></TD></TR>
<TR><TD colspan="9"><A HREF="#010">EXHIBIT INDEX</A></TD></TR>
<TR><TD colspan="9"><A HREF="a75593orex5-1.txt">EXHIBIT 5.1</A></TD></TR>
<TR><TD colspan="9"><A HREF="a75593orex23-1.txt">EXHIBIT 23.1</A></TD></TR>
<TR><TD colspan="9"><A HREF="a75593orex99-1.txt">EXHIBIT 99.1</A></TD></TR>
<TR><TD colspan="9"><A HREF="a75593orex99-2.txt">EXHIBIT 99.2</A></TD></TR>
</TABLE>
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<!-- link1 "PART II Information Required in the Registration Statement" -->
<DIV align="left"><A NAME="000"></A></DIV>
<P align="center"><FONT size="2"><B>PART II</B></FONT>

<P align="center"><FONT size="2"><B>Information Required in the Registration Statement</B></FONT>

<!-- link2 "Item&nbsp;3. Information Incorporated by Reference." -->
<DIV align="left"><A NAME="001"></A></DIV>
<P align="left"><FONT size="2"><B>Item&nbsp;3. Information Incorporated by Reference.</B></FONT>

<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Registrant hereby incorporates by reference into this registration
statement the following documents and information previously filed with the
Securities and Exchange Commission (the &#147;Commission&#148;):
</FONT>

<P>
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR valign="top">
   <TD width="1%" align="right" nowrap><FONT size="2">(a)</FONT></TD>
   <TD width="1%" nowrap><FONT size="2">&nbsp;&nbsp;</FONT></TD>
   <TD width="98%"><FONT size="2">The Registrant&#146;s Annual Report on Form&nbsp;10-K for the year ended December
31, 2000 filed on March&nbsp;29, 2001 with the Commission.</FONT></TD>
</TR>
<TR>
        <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR valign="top">
   <TD width="1%" align="right" nowrap><FONT size="2">(b)</FONT></TD>
   <TD width="1%" nowrap><FONT size="2">&nbsp;&nbsp;</FONT></TD>
   <TD width="98%"><FONT size="2">The Registrant&#146;s Quarterly Report on Form&nbsp;10-Q for the fiscal quarter
ended March&nbsp;31, 2001, filed with the Commission on May&nbsp;8, 2001, and the
Registrant&#146;s Quarterly Report on Form&nbsp;10-Q for the fiscal quarter ended
June&nbsp;30, 2001 filed with the Commission on August&nbsp;13, 2001.</FONT></TD>
</TR>
<TR>
        <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR valign="top">
   <TD width="1%" align="right" nowrap><FONT size="2">(c)</FONT></TD>
   <TD width="1%" nowrap><FONT size="2">&nbsp;&nbsp;</FONT></TD>
   <TD width="98%"><FONT size="2">The Registrant&#146;s Registration Statement on Form&nbsp;8-A12G filed with the
Commission on April&nbsp;14, 2000, pursuant to Section&nbsp;12(b) of the Securities
Exchange Act of 1934, as amended (the &#147;Exchange Act&#148;), in which are
described the terms, rights and provisions applicable to the Registrant&#146;s
outstanding Common Stock.</FONT></TD>
</TR>
</TABLE>
<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;All documents filed by the Registrant pursuant to Sections&nbsp;13(a), 13(c),
14 and 15(d) of the Exchange Act subsequent to the filing of this Registration
Statement and prior to the filing of a post-effective amendment which indicates
that all securities offered have been sold or which deregisters all securities
then remaining unsold shall be deemed to be incorporated by reference in this
Registration Statement and to be part hereof from the date of filing of such
documents. Any statement contained in a document incorporated or deemed to be
incorporated by reference herein shall be deemed to be modified or superseded
for purposes of this Registration Statement to the extent that a statement
contained herein or in any subsequently filed document which also is deemed to
be incorporated by reference herein modifies or supersedes such statement. Any
such statement so modified or superseded shall not be deemed, except as so
modified or superseded, to constitute a part of this Registration Statement.
</FONT>

<!-- link2 "Item&nbsp;4. Description of Securities." -->
<DIV align="left"><A NAME="002"></A></DIV>
<P align="left"><FONT size="2"><B>Item&nbsp;4. Description of Securities.</B></FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not applicable.
</FONT>
<!-- link2 "Item&nbsp;5. Interests of Named Experts and Counsel." -->
<DIV align="left"><A NAME="003"></A></DIV>
<P align="left"><FONT size="2"><B>Item&nbsp;5. Interests of Named Experts and Counsel.</B></FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;None.
</FONT>
<!-- link2 "Item&nbsp;6. Indemnification of Directors and Officers." -->
<DIV align="left"><A NAME="004"></A></DIV>
<P align="left"><FONT size="2"><B>Item&nbsp;6. Indemnification of Directors and Officers.</B></FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The General Corporation Law of Delaware (the &#147;DGCL&#148;) permits
indemnification of officers and directors of a corporation under certain
conditions and subject to certain limitations. The DGCL also provides that a
corporation has the power to maintain insurance on behalf of its officers and
directors against any liability asserted against such person and incurred by
him or her in such capacity, or arising out of his or her status as such,
whether or not the corporation would have the power to indemnify him or her
against such liability under the provisions of Section&nbsp;145. In addition, the
DGCL provides that expenses incurred by a director or executive officer in
defending any civil, criminal, administrative or investigative action, suit or
proceeding by reason of the fact that he or she is a director or officer of a
corporation (or is serving at a corporation&#146;s request as a director or officer
of another corporation) may be paid by a corporation in advance of the final
disposition of such action, suit or proceeding upon receipt of an undertaking
by or on behalf of such director or officer to repay such amount if it shall
ultimately be determined that he or she is not entitled to be indemnified by
the corporation as authorized by the relevant section of the DGCL.
</FONT>
<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Registrant&#146;s Certificate of Incorporation provides that its directors
shall not be personally liable to the Registrant and its stockholders for
monetary damages for breach of their fiduciary duty as directors. The
Registrant&#146;s Certificate of Incorporation and Bylaws provide for mandatory
indemnification of its directors and officers and permissible indemnification
of employees and other agents to the maximum extent permitted by law.
</FONT>
<P align="center"><FONT size="2">&nbsp;
</FONT>

<P align="center"><FONT size="2">II-1
</FONT>

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<H5 align="left"><A HREF="#toc">Table of Contents</A></H5><P>
<P><FONT size="2">The rights to indemnity continue as to a person who has ceased to be a
director, officer, employee or agent and inure to the benefit of the heirs,
executors and administrators of the person. This indemnification by the
Registrant does not eliminate a director&#146;s fiduciary duty, and in appropriate
circumstances equitable remedies such as injunctive or other forms of
non-monetary relief will remain available. In addition, each director of the
Registrant will continue to be subject to liability for breach of such
director&#146;s duty of loyalty for acts or omission not in good faith or involving
international misconduct, for knowing violations of law, for actions leading to
improper personal benefit to the director, and for payment of dividends or
approval of stock repurchases or redemptions that are unlawful under Section
174 of the DGCL. The provision also does not affect a director&#146;s
responsibilities under any other law, such as the federal securities laws or
state or federal environmental laws.
</FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Registrant has entered into indemnification agreements to such effect
with its officers and directors containing provisions which are in some
respects broader than the specific indemnification provisions contained in the
DGCL. The indemnification agreements may require the Registrant, among other
things, to indemnify such officers and directors against certain liabilities
that may arise by reason of their status or service as directors or officers
(other than liabilities arising from willful misconduct of a culpable nature)
and to advance their expenses incurred as a result of any proceeding against
them as to which they could be indemnified.
</FONT>
<!-- link2 "Item&nbsp;7. Exemption From Registration Claimed." -->
<DIV align="left"><A NAME="005"></A></DIV>
<P align="left"><FONT size="2"><B>Item&nbsp;7. Exemption From Registration Claimed.</B></FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not applicable.
</FONT>
<!-- link2 "Item&nbsp;8. Exhibits." -->
<DIV align="left"><A NAME="006"></A></DIV>
<P align="left"><FONT size="2"><B>Item&nbsp;8. Exhibits.</B></FONT>

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<TABLE cellspacing="0" border="0" cellpadding="0" width="95%">
<TR valign="bottom">
        <TD width="4%">&nbsp;</TD>
        <TD width="4%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="87%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD colspan="2" nowrap valign="top" align="center"><FONT size="1">Exhibit Number</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD colspan="2" nowrap align="left"><FONT size="1">Exhibit</FONT></TD>
</TR>
<TR valign="bottom">
        <TD colspan="2" valign="top" align="right"><HR size="1" noshade></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center"><HR size="1" noshade></TD>
</TR>
<TR valign="bottom">
        <TD valign="top" align="right"><FONT size="2">4.</FONT></TD>
        <TD valign="top" align="left"><FONT size="2">1(1)</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Specimen Common Stock Certificate.</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top" align="right"><FONT size="2">4.</FONT></TD>
        <TD valign="top" align="left"><FONT size="2">2(1)</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Second Amended and Restated Stockholders Rights Agreement, dated
November&nbsp;5, 1999, by and among the Registrant and certain stockholders
of the Registrant.</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top" align="right"><FONT size="2">4.</FONT></TD>
        <TD valign="top" align="left"><FONT size="2">3(2)</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Rights Agreement, dated as of May&nbsp;3, 2001, between the Company and
Equiserve Trust Company, N.A.</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top" align="right"><FONT size="2">5.</FONT></TD>
        <TD valign="top" align="left"><FONT size="2">1</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Opinion of Brobeck, Phleger &#038; Harrison LLP.</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top" align="right"><FONT size="2">23.</FONT></TD>
        <TD valign="top" align="left"><FONT size="2">1</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Consent of Ernst &#038; Young LLP, Independent Auditors.</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top" align="right"><FONT size="2">23.</FONT></TD>
        <TD valign="top" align="left"><FONT size="2">2</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Consent of Brobeck, Phleger &#038; Harrison LLP is contained in Exhibit&nbsp;5.1.</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top" align="right"><FONT size="2">24.</FONT></TD>
        <TD valign="top" align="left"><FONT size="2">1</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Power of Attorney. Reference is made to page II-4 of this Registration Statement.</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top" align="right"><FONT size="2">99.</FONT></TD>
        <TD valign="top" align="left"><FONT size="2">1</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Illumina, Inc. 2000 Stock Plan (as Amended and Restated Effective
March&nbsp;20, 2001).</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top" align="right"><FONT size="2">99.</FONT></TD>
        <TD valign="top" align="left"><FONT size="2">2</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Illumina, Inc. 2000 Employee Stock Purchase Plan (as Amended and
Restated Effective March&nbsp;20, 2001).</FONT></TD>
</TR>
</TABLE>
</CENTER>
<P>
<HR size="1" width="18%" align="left" noshade>
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR valign="top">
      <TD width="1%" align="left" nowrap><FONT size="2">(1)</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="96%"><FONT size="2">Incorporated by reference to the same numbered exhibit filed with
our Registration Statement on Form&nbsp;S-1 (333-33922) filed April&nbsp;3,
2000, as amended.</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="top">
      <TD width="1%" align="left" nowrap><FONT size="2">(2)</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="96%"><FONT size="2">Incorporated by reference to the same numbered exhibit filed with
our Registration Statement on Form&nbsp;8-A (000-30361) filed May&nbsp;14, 2001.</FONT></TD>
</TR>
</TABLE>
<!-- link2 "Item&nbsp;9. Undertakings." -->
<DIV align="left"><A NAME="007"></A></DIV>
<P align="left"><FONT size="2"><B>Item&nbsp;9. Undertakings.</B></FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a)&nbsp; The undersigned Registrant hereby undertakes:
</FONT>
<P>
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR valign="top">
   <TD width="1%" nowrap><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</FONT></TD>
   <TD width="1%" align="right" nowrap><FONT size="2">1)</FONT></TD>
   <TD width="1%" nowrap><FONT size="2">&nbsp;&nbsp;</FONT></TD>
   <TD width="97%"><FONT size="2">To file, during any period in which offers or sales are being
made, a post-effective amendment to this Registration Statement to
include any material information with respect to the plan of
distribution not previously disclosed in this Registration Statement
or any material change to such information in this Registration
Statement;</FONT></TD>
</TR>
<TR>
        <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR valign="top">
   <TD width="1%" nowrap><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</FONT></TD>
   <TD width="1%" align="right" nowrap><FONT size="2">2)</FONT></TD>
   <TD width="1%" nowrap><FONT size="2">&nbsp;&nbsp;</FONT></TD>
   <TD width="97%"><FONT size="2">That, for the purpose of determining any liability under the
Securities Act, each such post-effective amendment shall be deemed
to be a new registration statement relating to the securities
offered therein, and the offering of such securities at that time
shall be deemed to be the initial <I>bona fide </I>offering thereof; and</FONT></TD>
</TR>
</TABLE>
<P align="center"><FONT size="2">&nbsp;
</FONT>

<P align="center"><FONT size="2">II-2
</FONT>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left"><A HREF="#toc">Table of Contents</A></H5><P>



<P>
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR valign="top">
   <TD width="1%" nowrap><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</FONT></TD>
   <TD width="1%" align="right" nowrap><FONT size="2">3)</FONT></TD>
   <TD width="1%" nowrap><FONT size="2">&nbsp;&nbsp;</FONT></TD>
   <TD width="97%"><FONT size="2">To remove from registration by means of a post-effective
amendment any of the securities being registered which remain unsold
at the termination of the Purchase Plan and the 2000 Option Plan.</FONT></TD>
</TR>
</TABLE>
<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b)&nbsp; The undersigned Registrant hereby undertakes that, for purposes of
determining any liability under the Securities Act, each filing of the
Registrant&#146;s annual report pursuant to Section&nbsp;13(a) or Section&nbsp;15(d) of the
Exchange Act (and, where applicable, each filing of an employee benefit plan&#146;s
annual report pursuant to Section&nbsp;15(d) of the Exchange Act) that is
incorporated by reference in this Registration Statement shall be deemed to be
a new registration statement relating to the securities offered therein, and
the offering of such securities at that time shall be deemed to be an initial
<I>bona fide </I>offering thereof.
</FONT>
<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c)&nbsp; Insofar as indemnification for liabilities arising under the
Securities Act may be permitted to directors, officers and controlling persons
of the Registrant pursuant to the indemnification provisions summarized in Item
6 or otherwise, the Registrant has been advised that, in the opinion of the
Commission, such indemnification is against public policy as expressed in the
Securities Act and is, therefore, unenforceable. In the event that a claim for
indemnification against such liabilities (other than the payment by the
Registrant of expenses incurred or paid by a director, officer, or controlling
person of the Registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the Registrant will, unless in
the opinion of its counsel the matter has been settled by controlling
precedent, submit to a court of appropriate jurisdiction the question whether
such indemnification by it is against public policy as expressed in the
Securities Act and will be governed by the final adjudication of such issue.
</FONT>
<P align="center"><FONT size="2">&nbsp;
</FONT>

<P align="center"><FONT size="2">II-3
</FONT>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left"><A HREF="#toc">Table of Contents</A></H5><P>
<!-- link1 "SIGNATURES" -->
<DIV align="left"><A NAME="008"></A></DIV>
<P align="center"><FONT size="2"><B>SIGNATURES</B></FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act, the Registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form&nbsp;S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized in the City of San Diego, State of California on September&nbsp;6, 2001.
</FONT>
<P>
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR valign="top">
        <TD width="48%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="4%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="48%"><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR valign="top">
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD COLSPAN="2"><FONT size="2"><B>ILLUMINA, INC.</B></FONT></TD>
</TR>
<TR valign="top">
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR valign="top">
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR valign="top">
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">By:</FONT></TD>
        <TD><FONT size="2">/s/ Jay T. Flatley</FONT></TD>
</TR>
<TR valign="top">
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2"><HR SIZE="1"></FONT></TD>
</TR>
<TR valign="top">
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">Jay T. Flatley</FONT></TD>
</TR>
<TR valign="top">
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD><FONT size="2">President and Chief Executive Officer</FONT></TD>
</TR>
</TABLE>
<!-- link1 "POWER OF ATTORNEY" -->
<DIV align="left"><A NAME="009"></A></DIV>
<P align="center"><FONT size="2"><B>POWER OF ATTORNEY</B></FONT>

<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;That the undersigned officers and directors of Illumina, Inc., a Delaware
corporation, do hereby constitute and appoint Jay T. Flatley and John R.
Steulpnagel, and each of them, the lawful attorneys-in-fact and agents with
full power and authority to do any and all acts and things and to execute any
and all instruments which said attorneys and agents, and any one of them,
determine may be necessary or advisable or required to enable said corporation
to comply with the Securities Act, and any rules or regulations or requirements
of the Commission in connection with this Registration Statement. Without
limiting the generality of the foregoing power and authority, the powers
granted include the power and authority to sign the names of the undersigned
officers and directors in the capacities indicated below to this Registration
Statement, to any and all amendments, both pre-effective and post-effective,
and supplements to this Registration Statement, and to any and all instruments
or documents filed as part of or in conjunction with this Registration
Statement or amendments or supplements thereof, and each of the undersigned
hereby ratifies and confirms that all said attorneys and agents, or any one of
them, shall do or cause to be done by virtue hereof. This Power of Attorney
may be signed in several counterparts.
</FONT>

<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<B>IN WITNESS WHEREOF</B>, each of the undersigned has executed this Power of
Attorney as of the date indicated.
</FONT>

<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act, this Registration
Statement has been signed below by the following persons in the capacities and
on the dates indicated.
</FONT>

<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="100%">
<TR valign="bottom">
        <TD width="45%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="25%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="20%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="LEFT"><FONT size="1">Signature</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="LEFT"><FONT size="1">Title</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="LEFT"><FONT size="1">Date</FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><HR size="1" noshade></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center"><HR size="1" noshade></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center"><HR size="1" noshade></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ Jay T. Flatley
<HR size="1" noshade>
Jay T. Flatley</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
President, Chief
Executive Officer
and Director
(Principal
Executive Officer)
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">September&nbsp;6, 2001</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ Timothy M. Kish
<HR size="1" noshade>
Timothy M. Kish</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Chief Financial
Officer (Principal
Financial and
Accounting Officer)
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">September&nbsp;6, 2001</FONT></TD>
</TR>
</TABLE>
</CENTER>
<P align="center"><FONT size="2">&nbsp;
</FONT>

<P align="center"><FONT size="2">II-4
</FONT>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left"><A HREF="#toc">Table of Contents</A></H5><P>
<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="100%">
<TR valign="bottom">
        <TD width="45%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="25%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="20%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="LEFT"><FONT size="1">Signature</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="LEFT"><FONT size="1">Title</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="LEFT"><FONT size="1">Date</FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><HR size="1" noshade></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center"><HR size="1" noshade></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center"><HR size="1" noshade></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ John R. Stuelpnagel, D.V.M.
<HR size="1" noshade>
John R. Stuelpnagel, D.V.M.</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Director
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">September&nbsp;6, 2001</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ R. Scott Greer
<HR size="1" noshade>
R. Scott Greer</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Director
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">September&nbsp;6, 2001</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ Robert T. Nelsen
<HR size="1" noshade>
Robert T. Nelsen</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Director
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">September&nbsp;6, 2001</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ George Poste, DVM, Ph. D.
<HR size="1" noshade>
George Poste, DVM, Ph. D.</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Director
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">September&nbsp;6, 2001</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ William Rastetter, Ph. D.
<HR size="1" noshade>
William Rastetter, Ph. D.</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Director
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">September&nbsp;6, 2001</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">/s/ David R. Walt, Ph. D.
<HR size="1" noshade>
David R. Walt, Ph. D.</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Director
</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">September&nbsp;6, 2001</FONT></TD>
</TR>
</TABLE>
</CENTER>
<P align="center"><FONT size="2">&nbsp;
</FONT>

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<P><HR noshade><P>
<H5 align="left"><A HREF="#toc">Table of Contents</A></H5><P>
<P align="center"><FONT size="2">SECURITIES AND EXCHANGE COMMISSION<BR>
WASHINGTON, D.C. 20549</FONT>

<P align="center"><FONT size="2">EXHIBITS</FONT>

<P align="center"><FONT size="2">TO</FONT>

<P align="center"><FONT size="2">FORM S-8</FONT>

<P align="center"><FONT size="2">UNDER</FONT>

<P align="center"><FONT size="2">SECURITIES ACT OF 1933</FONT>

<P align="center"><FONT size="2">ILLUMINA, INC.</FONT>

<P align="center"><FONT size="2">&nbsp;
</FONT>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left"><A HREF="#toc">Table of Contents</A></H5><P>


<!-- link1 "EXHIBIT INDEX" -->
<DIV align="left"><A NAME="010"></A></DIV>
<P align="center"><FONT size="2">EXHIBIT INDEX</FONT>

<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="95%">
<TR valign="bottom">
        <TD width="4%">&nbsp;</TD>
        <TD width="4%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="87%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD colspan="2" nowrap valign="top" align="right"><FONT size="1">Exhibit Number</FONT></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="LEFT"><FONT size="1">Exhibit</FONT></TD>
</TR>
<TR valign="bottom">
        <TD colspan="2" valign="top" align="right"><HR size="1" noshade></TD>
        <TD><FONT size="1">&nbsp;</FONT></TD>
        <TD nowrap align="center"><HR size="1" noshade></TD>
</TR>
<TR valign="bottom">
        <TD valign="top" align="right"><FONT size="2">4.</FONT></TD>
        <TD valign="top" align="left"><FONT size="2">1(1)</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Specimen Common Stock Certificate.</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top" align="right"><FONT size="2">4.</FONT></TD>
        <TD valign="top" align="left"><FONT size="2">2(1)</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Second Amended and Restated Stockholders Rights Agreement, dated
November&nbsp;5, 1999, by and among the Registrant and certain stockholders
of the Registrant.</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top" align="right"><FONT size="2">4.</FONT></TD>
        <TD valign="top" align="left"><FONT size="2">3(2)</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Rights Agreement, dated as of May&nbsp;3, 2001, between the Company and
Equiserve Trust Company, N.A.</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top" align="right"><FONT size="2">5.</FONT></TD>
        <TD valign="top" align="left"><FONT size="2">1</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Opinion of Brobeck, Phleger &#038; Harrison LLP.</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top" align="right"><FONT size="2">23.</FONT></TD>
        <TD valign="top" align="left"><FONT size="2">1</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Consent of Ernst &#038; Young LLP, Independent Auditors.</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top" align="right"><FONT size="2">23.</FONT></TD>
        <TD valign="top" align="left"><FONT size="2">2</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Consent of Brobeck, Phleger &#038; Harrison LLP is contained in Exhibit&nbsp;5.1.</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top" align="right"><FONT size="2">24.</FONT></TD>
        <TD valign="top" align="left"><FONT size="2">1</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Power of Attorney. Reference is made to page II-4 of this Registration Statement.</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top" align="right"><FONT size="2">99.</FONT></TD>
        <TD valign="top" align="left"><FONT size="2">1</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Illumina, Inc. 2000 Stock Plan (as Amended and Restated Effective
March&nbsp;20, 2001).</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top" align="right"><FONT size="2">99.</FONT></TD>
        <TD valign="top" align="left"><FONT size="2">2</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
Illumina, Inc. 2000 Employee Stock Purchase Plan (as Amended and
Restated Effective March&nbsp;20, 2001).</FONT></TD>
</TR>
</TABLE>
</CENTER>
<P>
<HR size="1" width="18%" align="left" noshade>
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR valign="top">
      <TD width="1%" align="left" nowrap><FONT size="2">(1)</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="96%"><FONT size="2">Incorporated by reference to the same numbered exhibit filed with
our Registration Statement on Form&nbsp;S-1 (333-33922) filed April&nbsp;3,
2000, as amended.</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="top">
      <TD width="1%" align="left" nowrap><FONT size="2">(2)</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="96%"><FONT size="2">Incorporated by reference to the same numbered exhibit filed with
our Registration Statement on Form&nbsp;8-A (000-30361) filed May&nbsp;14, 2001.</FONT></TD>
</TR>
</TABLE>

<P align="center"><FONT size="2">&nbsp;</FONT>

</BODY>
</HTML>
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Illumina, Inc. Form S-8
Table of Contents
As filed with the Securities and Exchange Commission on September 6, 2001
Registration No. _________
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-8
REGISTRATION STATEMENT
Under
The Securities Act of 1933
__________
ILLUMINA, INC.
(Exact name of registrant as specified in its charter)
Delaware
(State or other jurisdiction
of incorporation or organization)
33-0804655
(IRS Employer Identification No.)
9390 Towne Centre Drive, Suite 200
San Diego, California 92121
(Address of principal executive offices) (Zip Code)
__________
2000 Stock Plan
2000 Employee Stock Purchase Plan
(Full title of the Plan)
____________
Jay T. Flatley
Chief Executive Officer and President
Illumina, Inc.
9390 Towne Centre Drive, Suite 200, San Diego, California, 92121
(Name and address of agent for service)
(858) 587-4290
(Telephone number, including area code, of agent for service)
___________
CALCULATION OF REGISTRATION FEE
Offering
Amount of
Amount to be
Price
Aggregate
Registration
Title of Securities to be Registered
Registered (1)
per Share
Offering Price
Fee
2000 Stock Plan
Common Stock, $0.01 par value
4,149,460 shares (2)
$
8.65
$
12,975,000
$
3,243.75
(3)
2000 Employee Stock Purchase Plan
Common Stock, $0.01 par value
958,946 shares (4)
$
8.65
$
8,294,883
$
2,073.72
(5)
Aggregate Registration Fee
$
5,317.47
(1)
This Registration Statement shall also cover any additional shares of
Common Stock, par value $0.01 (the "Common Stock"), of Illumina, Inc. (the
"Registrant") which become issuable under the Illumina, Inc. 2000 Stock
Plan (the "2000 Option Plan") and the Illumina, Inc. 2000 Employee Stock
Purchase Plan (the "Purchase Plan") by reason of any stock dividend, stock
split, recapitalization or other similar transaction effected without the
Registrant's receipt of consideration which results in an increase in the
number of outstanding shares of Common Stock.
Table of Contents
(2)
1,500,000 shares of the 4,149,460 shares of Common Stock subject to this
Registration Statement were available for issuance under the 2000 Option
Plan effective as of January 2, 2001. The remaining 2,649,460 shares of
the 4,149,460 shares of Common Stock subject to this Registration
Statement were transferred to the 2000 Option Plan from the Registrant's
1998 Incentive Stock Plan (the "1998 Option Plan"). Such shares were
previously registered on Form S-8 Registration Statement No. 333-42866
filed on August 2, 2000 (the "2000 Registration Statement").
(3)
The Registration Fee with respect to the 2000 Option Plan is based solely
on 1,500,000 shares of Common Stock newly available for issuance under the
2000 Option Plan and is calculated solely for purposes of this offering
under Rule 457(h) of the Securities Act of 1933 on the basis of the
average of the high and low selling price per share of Common Stock on
August 31, 2001, as reported by the Nasdaq National Market. The
applicable filing fees for the remaining 2,649,460 shares transferred from
the 2000 Option Plan from the 1998 Option Plan were paid in connection
with the 2000 Registration Statement.
(4)
958,946 shares of Common Stock were available for issuance under the
Purchase Plan effective as of January 2, 2001.
(5)
The Registration Fee with respect to the Purchase Plan is based solely on
958,946 shares of Common Stock newly available for issuance under the
Purchase Plan and is calculated solely for purposes of this offering under
Rule 457(h) of the Securities Act of 1933 on the basis of the average of
the high and low selling price per share of Common Stock on August 31,
2001, as reported by the Nasdaq National Market.
TABLE OF CONTENTS
PART II Information Required in the Registration Statement
Item 3. Information Incorporated by Reference.
Item 4. Description of Securities.
Item 5. Interests of Named Experts and Counsel.
Item 6. Indemnification of Directors and Officers.
Item 7. Exemption From Registration Claimed.
Item 8. Exhibits.
Item 9. Undertakings.
SIGNATURES
POWER OF ATTORNEY
EXHIBIT INDEX
EXHIBIT 5.1
EXHIBIT 23.1
EXHIBIT 99.1
EXHIBIT 99.2
Table of Contents
PART II
Information Required in the Registration Statement
Item 3. Information Incorporated by Reference.
The Registrant hereby incorporates by reference into this registration
statement the following documents and information previously filed with the
Securities and Exchange Commission (the "Commission"):
(a)
The Registrant's Annual Report on Form 10-K for the year ended December
31, 2000 filed on March 29, 2001 with the Commission.
(b)
The Registrant's Quarterly Report on Form 10-Q for the fiscal quarter
ended March 31, 2001, filed with the Commission on May 8, 2001, and the
Registrant's Quarterly Report on Form 10-Q for the fiscal quarter ended
June 30, 2001 filed with the Commission on August 13, 2001.
(c)
The Registrant's Registration Statement on Form 8-A12G filed with the
Commission on April 14, 2000, pursuant to Section 12(b) of the Securities
Exchange Act of 1934, as amended (the "Exchange Act"), in which are
described the terms, rights and provisions applicable to the Registrant's
outstanding Common Stock.
All documents filed by the Registrant pursuant to Sections 13(a), 13(c),
14 and 15(d) of the Exchange Act subsequent to the filing of this Registration
Statement and prior to the filing of a post-effective amendment which indicates
that all securities offered have been sold or which deregisters all securities
then remaining unsold shall be deemed to be incorporated by reference in this
Registration Statement and to be part hereof from the date of filing of such
documents. Any statement contained in a document incorporated or deemed to be
incorporated by reference herein shall be deemed to be modified or superseded
for purposes of this Registration Statement to the extent that a statement
contained herein or in any subsequently filed document which also is deemed to
be incorporated by reference herein modifies or supersedes such statement. Any
such statement so modified or superseded shall not be deemed, except as so
modified or superseded, to constitute a part of this Registration Statement.
Item 4. Description of Securities.
Not applicable.
Item 5. Interests of Named Experts and Counsel.
None.
Item 6. Indemnification of Directors and Officers.
The General Corporation Law of Delaware (the "DGCL") permits
indemnification of officers and directors of a corporation under certain
conditions and subject to certain limitations. The DGCL also provides that a
corporation has the power to maintain insurance on behalf of its officers and
directors against any liability asserted against such person and incurred by
him or her in such capacity, or arising out of his or her status as such,
whether or not the corporation would have the power to indemnify him or her
against such liability under the provisions of Section 145. In addition, the
DGCL provides that expenses incurred by a director or executive officer in
defending any civil, criminal, administrative or investigative action, suit or
proceeding by reason of the fact that he or she is a director or officer of a
corporation (or is serving at a corporation's request as a director or officer
of another corporation) may be paid by a corporation in advance of the final
disposition of such action, suit or proceeding upon receipt of an undertaking
by or on behalf of such director or officer to repay such amount if it shall
ultimately be determined that he or she is not entitled to be indemnified by
the corporation as authorized by the relevant section of the DGCL.
The Registrant's Certificate of Incorporation provides that its directors
shall not be personally liable to the Registrant and its stockholders for
monetary damages for breach of their fiduciary duty as directors. The
Registrant's Certificate of Incorporation and Bylaws provide for mandatory
indemnification of its directors and officers and permissible indemnification
of employees and other agents to the maximum extent permitted by law.
II-1
Table of Contents
The rights to indemnity continue as to a person who has ceased to be a
director, officer, employee or agent and inure to the benefit of the heirs,
executors and administrators of the person. This indemnification by the
Registrant does not eliminate a director's fiduciary duty, and in appropriate
circumstances equitable remedies such as injunctive or other forms of
non-monetary relief will remain available. In addition, each director of the
Registrant will continue to be subject to liability for breach of such
director's duty of loyalty for acts or omission not in good faith or involving
international misconduct, for knowing violations of law, for actions leading to
improper personal benefit to the director, and for payment of dividends or
approval of stock repurchases or redemptions that are unlawful under Section
174 of the DGCL. The provision also does not affect a director's
responsibilities under any other law, such as the federal securities laws or
state or federal environmental laws.
The Registrant has entered into indemnification agreements to such effect
with its officers and directors containing provisions which are in some
respects broader than the specific indemnification provisions contained in the
DGCL. The indemnification agreements may require the Registrant, among other
things, to indemnify such officers and directors against certain liabilities
that may arise by reason of their status or service as directors or officers
(other than liabilities arising from willful misconduct of a culpable nature)
and to advance their expenses incurred as a result of any proceeding against
them as to which they could be indemnified.
Item 7. Exemption From Registration Claimed.
Not applicable.
Item 8. Exhibits.
Exhibit Number
Exhibit
4.
1(1)
Specimen Common Stock Certificate.
4.
2(1)
Second Amended and Restated Stockholders Rights Agreement, dated
November 5, 1999, by and among the Registrant and certain stockholders
of the Registrant.
4.
3(2)
Rights Agreement, dated as of May 3, 2001, between the Company and
Equiserve Trust Company, N.A.
5.
1
Opinion of Brobeck, Phleger & Harrison LLP.
23.
1
Consent of Ernst & Young LLP, Independent Auditors.
23.
2
Consent of Brobeck, Phleger & Harrison LLP is contained in Exhibit 5.1.
24.
1
Power of Attorney. Reference is made to page II-4 of this Registration Statement.
99.
1
Illumina, Inc. 2000 Stock Plan (as Amended and Restated Effective
March 20, 2001).
99.
2
Illumina, Inc. 2000 Employee Stock Purchase Plan (as Amended and
Restated Effective March 20, 2001).
(1)
Incorporated by reference to the same numbered exhibit filed with
our Registration Statement on Form S-1 (333-33922) filed April 3,
2000, as amended.
(2)
Incorporated by reference to the same numbered exhibit filed with
our Registration Statement on Form 8-A (000-30361) filed May 14, 2001.
Item 9. Undertakings.
(a)  The undersigned Registrant hereby undertakes:
1)
To file, during any period in which offers or sales are being
made, a post-effective amendment to this Registration Statement to
include any material information with respect to the plan of
distribution not previously disclosed in this Registration Statement
or any material change to such information in this Registration
Statement;
2)
That, for the purpose of determining any liability under the
Securities Act, each such post-effective amendment shall be deemed
to be a new registration statement relating to the securities
offered therein, and the offering of such securities at that time
shall be deemed to be the initial
bona fide
offering thereof; and
II-2
Table of Contents
3)
To remove from registration by means of a post-effective
amendment any of the securities being registered which remain unsold
at the termination of the Purchase Plan and the 2000 Option Plan.
(b)  The undersigned Registrant hereby undertakes that, for purposes of
determining any liability under the Securities Act, each filing of the
Registrant's annual report pursuant to Section 13(a) or Section 15(d) of the
Exchange Act (and, where applicable, each filing of an employee benefit plan's
annual report pursuant to Section 15(d) of the Exchange Act) that is
incorporated by reference in this Registration Statement shall be deemed to be
a new registration statement relating to the securities offered therein, and
the offering of such securities at that time shall be deemed to be an initial
bona fide
offering thereof.
(c)  Insofar as indemnification for liabilities arising under the
Securities Act may be permitted to directors, officers and controlling persons
of the Registrant pursuant to the indemnification provisions summarized in Item
6 or otherwise, the Registrant has been advised that, in the opinion of the
Commission, such indemnification is against public policy as expressed in the
Securities Act and is, therefore, unenforceable. In the event that a claim for
indemnification against such liabilities (other than the payment by the
Registrant of expenses incurred or paid by a director, officer, or controlling
person of the Registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the Registrant will, unless in
the opinion of its counsel the matter has been settled by controlling
precedent, submit to a court of appropriate jurisdiction the question whether
such indemnification by it is against public policy as expressed in the
Securities Act and will be governed by the final adjudication of such issue.
II-3
Table of Contents
SIGNATURES
Pursuant to the requirements of the Securities Act, the Registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized in the City of San Diego, State of California on September 6, 2001.
ILLUMINA, INC.
By:
/s/ Jay T. Flatley
Jay T. Flatley
President and Chief Executive Officer
POWER OF ATTORNEY
That the undersigned officers and directors of Illumina, Inc., a Delaware
corporation, do hereby constitute and appoint Jay T. Flatley and John R.
Steulpnagel, and each of them, the lawful attorneys-in-fact and agents with
full power and authority to do any and all acts and things and to execute any
and all instruments which said attorneys and agents, and any one of them,
determine may be necessary or advisable or required to enable said corporation
to comply with the Securities Act, and any rules or regulations or requirements
of the Commission in connection with this Registration Statement. Without
limiting the generality of the foregoing power and authority, the powers
granted include the power and authority to sign the names of the undersigned
officers and directors in the capacities indicated below to this Registration
Statement, to any and all amendments, both pre-effective and post-effective,
and supplements to this Registration Statement, and to any and all instruments
or documents filed as part of or in conjunction with this Registration
Statement or amendments or supplements thereof, and each of the undersigned
hereby ratifies and confirms that all said attorneys and agents, or any one of
them, shall do or cause to be done by virtue hereof. This Power of Attorney
may be signed in several counterparts.
IN WITNESS WHEREOF
, each of the undersigned has executed this Power of
Attorney as of the date indicated.
Pursuant to the requirements of the Securities Act, this Registration
Statement has been signed below by the following persons in the capacities and
on the dates indicated.
Signature
Title
Date
/s/ Jay T. Flatley
Jay T. Flatley
President, Chief
Executive Officer
and Director
(Principal
Executive Officer)
September 6, 2001
/s/ Timothy M. Kish
Timothy M. Kish
Chief Financial
Officer (Principal
Financial and
Accounting Officer)
September 6, 2001
II-4
Table of Contents
Signature
Title
Date
/s/ John R. Stuelpnagel, D.V.M.
John R. Stuelpnagel, D.V.M.
Director
September 6, 2001
/s/ R. Scott Greer
R. Scott Greer
Director
September 6, 2001
/s/ Robert T. Nelsen
Robert T. Nelsen
Director
September 6, 2001
/s/ George Poste, DVM, Ph. D.
George Poste, DVM, Ph. D.
Director
September 6, 2001
/s/ William Rastetter, Ph. D.
William Rastetter, Ph. D.
Director
September 6, 2001
/s/ David R. Walt, Ph. D.
David R. Walt, Ph. D.
Director
September 6, 2001
Table of Contents
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
EXHIBITS
TO
FORM S-8
UNDER
SECURITIES ACT OF 1933
ILLUMINA, INC.
Table of Contents
EXHIBIT INDEX
Exhibit Number
Exhibit
4.
1(1)
Specimen Common Stock Certificate.
4.
2(1)
Second Amended and Restated Stockholders Rights Agreement, dated
November 5, 1999, by and among the Registrant and certain stockholders
of the Registrant.
4.
3(2)
Rights Agreement, dated as of May 3, 2001, between the Company and
Equiserve Trust Company, N.A.
5.
1
Opinion of Brobeck, Phleger & Harrison LLP.
23.
1
Consent of Ernst & Young LLP, Independent Auditors.
23.
2
Consent of Brobeck, Phleger & Harrison LLP is contained in Exhibit 5.1.
24.
1
Power of Attorney. Reference is made to page II-4 of this Registration Statement.
99.
1
Illumina, Inc. 2000 Stock Plan (as Amended and Restated Effective
March 20, 2001).
99.
2
Illumina, Inc. 2000 Employee Stock Purchase Plan (as Amended and
Restated Effective March 20, 2001).
(1)
Incorporated by reference to the same numbered exhibit filed with
our Registration Statement on Form S-1 (333-33922) filed April 3,
2000, as amended.
(2)
Incorporated by reference to the same numbered exhibit filed with
our Registration Statement on Form 8-A (000-30361) filed May 14, 2001.