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<P align="center"><FONT size="5"><B>SECURITIES AND EXCHANGE COMMISSION</B></FONT><BR>
Washington, D.C. 20549

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<P align="center"><FONT size="5"><B>Form&nbsp;S-8</B></FONT><BR>
<B>REGISTRATION STATEMENT<BR>
Under<BR>
THE SECURITIES ACT OF 1933</B>

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<P align="center"><FONT size="6">AURORA BIOSCIENCES CORPORATION</FONT><BR>

<FONT size="2">(Exact Name Of Registrant As Specified In Its Charter)</FONT>

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        <TD width="51%">&nbsp;</TD>
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        <TD align="center" valign="top"><DIV style="margin-left:10px; text-indent:-10px"><B>Delaware</B><BR>
<FONT size="2">(State or Other Jurisdiction of<BR>
Incorporation or Organization)</FONT></DIV></TD>
        <TD></TD>
        <TD  align="center" valign="top"><DIV style="margin-left:10px; text-indent:-10px">
33-0669859<BR>
<FONT size="2">(I.R.S. Employer Identification No.)</FONT></DIV></TD>
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<P align="center">11010 Torreyana Road<BR>
San Diego, California 92121<BR>
(858)&nbsp;404-6600<BR>

<FONT size="2">(Address, Including Zip Code, and Telephone Number, Including Area Code, of Registrant&#146;s Principal Executive Offices)</FONT>

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<P align="center">1993 STOCK OPTION PLAN OF PANVERA CORPORATION<BR>

<FONT size="2">(Full Title of the Plan)</FONT>

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<P align="center">Stuart J. M. Collinson<BR>
Chairman, Chief Executive Officer and President<BR>
AURORA BIOSCIENCES CORPORATION<BR>
11010 Torreyana Road<BR>
San Diego, California 92121<BR>
(858)&nbsp;404-6600<BR>

<FONT size="2">(Name, Address, Including Zip Code, and Telephone Number, Including Area Code, of Agent for Service)</FONT>

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<P align="center"><I>Copies to</I>:<BR>
Thomas A. Coll, Esq.<BR>
COOLEY GODWARD LLP<BR>
4365 Executive Drive, Suite&nbsp;1100<BR>
San Diego, California 92121<BR>
(858)&nbsp;550-6000

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<P align="center"><B>CALCULATION OF REGISTRATION FEE</B></P>

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        <TD></TD>
        <TD></TD>
        <TD></TD>
        <TD></TD>
        <TD></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>Proposed</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>Proposed</B></FONT></TD>
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        <TD nowrap align="center"><FONT size="2"><B>Title of</B></FONT></TD>
        <TD></TD>
        <TD></TD>
        <TD></TD>
        <TD></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>maximum</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>maximum</B></FONT></TD>
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        <TD nowrap align="center"><FONT size="2"><B>Securities to be</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>Amount to be</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>offering price per</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>aggregate</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>Amount of</B></FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><FONT size="2"><B>registered (1)</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>registered (1)</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>share (2)</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>offering price (2)</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center" colspan="3"><FONT size="2"><B>registration fee (2)</B></FONT></TD>
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        <TD colspan="17"><HR size="1"></TD>
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        <TD><FONT size="3">Common Stock,
$0.001 par value</FONT></TD>
        <TD></TD>
        <TD></TD>
        <TD align="right" nowrap><FONT size="3">260,222</FONT></TD>
        <TD></TD>
        <TD></TD>
        <TD></TD>
<TD align="right" nowrap><FONT size="3">See note 2</FONT></TD>
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        <TD align="right" nowrap><FONT size="3">See note 2</FONT></TD>
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        <TD align="right" nowrap><FONT size="3">See note 2</FONT></TD>
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      <TD width="1%" align="left">(1)</TD>
        <TD width="3%">&nbsp;</TD>
        <TD width="96%">On March&nbsp;1, 2001, the Registrant completed the acquisition of PanVera
Corporation, a Wisconsin corporation (&#147;PanVera&#148;). In connection with the
acquisition, the Registrant assumed the obligations under the 1993 Stock
Option Plan of PanVera Corporation (the &#147;Plan&#148;). The Registrant does not
anticipate issuing any additional stock options under the Plan. The
number of shares being registered represents the aggregate number of
options to purchase shares of the Registrant&#146;s Common Stock assumed in
connection with the acquisition.</TD>
</TR>

<TR><TD><TR><TD><TR><TD><TR><TD><TR><TD><TR><TD><TR><TD><TR><TD>

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      <TD width="1%" align="left">(2)</TD>
        <TD width="3%">&nbsp;</TD>
        <TD width="96%">Pursuant to Rule&nbsp;429, the Registrant prepaid the registration fee for the
entire 260,222 shares under the Plan when it registered up to 1,900,000
shares of Common Stock pursuant to a Registration Statement on Form&nbsp;S-4
(File Number 333-54638) filed on January&nbsp;30, 2001.<BR>&nbsp;</TD>
</TR>
</TABLE>

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<P align="center">&nbsp;
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<A name="toc"><DIV align="CENTER"><U><B>TABLE OF CONTENTS</B></U></DIV></A>

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<TR><TD></TD><TD colspan="8"><A HREF="#000">Item&nbsp;3. INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#001">Item&nbsp;4. DESCRIPTION OF SECURITIES</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#002">Item&nbsp;5. INTERESTS OF NAMED EXPERTS AND COUNSEL</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#003">Item&nbsp;6. INDEMNIFICATION OF DIRECTORS AND OFFICERS</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#004">Item&nbsp;7. EXEMPTION FROM REGISTRATION CLAIMED</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#005">Item&nbsp;8. EXHIBITS</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#006">Item&nbsp;9. UNDERTAKINGS</A></TD></TR>
<TR><TD colspan="9"><A HREF="#007">SIGNATURES</A></TD></TR>
<TR><TD colspan="9"><A HREF="#008">EXHIBIT INDEX</A></TD></TR>
<TR><TD colspan="9"><A HREF="a71217orex5-1.txt">EXHIBIT 5.1</A></TD></TR>
<TR><TD colspan="9"><A HREF="a71217orex23-1.txt">EXHIBIT 23.1</A></TD></TR>
<TR><TD colspan="9"><A HREF="a71217orex99-1.txt">EXHIBIT 99.1</A></TD></TR>
<TR><TD colspan="9"><A HREF="a71217orex99-2.txt">EXHIBIT 99.2</A></TD></TR>
<TR><TD colspan="9"><A HREF="a71217orex99-3.txt">EXHIBIT 99.3</A></TD></TR>
<TR><TD colspan="9"><A HREF="a71217orex99-4.txt">EXHIBIT 99.4</A></TD></TR>
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<!-- link2 "Item&nbsp;3. INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE" -->
<DIV align="left"><A NAME="000"></A></DIV>
<DIV align="left"><A name="000"></A></DIV>
<P align="left"><B>Item&nbsp;3. INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE</B>

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The following documents filed by AURORA BIOSCIENCES CORPORATION (the
&#147;Company&#148;) with the Securities and Exchange Commission are incorporated by
reference into this Registration Statement:

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a)&nbsp;The Company&#146;s annual report on Form&nbsp;10-K for the year ended December
31, 2000.

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b)&nbsp;All other reports filed pursuant to Sections&nbsp;13(a) or 15(d) of the
Securities Exchange Act of 1934, as amended (the &#147;Exchange Act&#148;) since the end
of the fiscal year covered by the annual report referred to in (a)&nbsp;above.

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c)&nbsp;The description of the Company&#146;s Common Stock which is contained in a
registration statement on Form&nbsp;S-1 filed on March&nbsp;14, 1997 (Registration No.
33-23407), including any amendment or report filed for the purposes of updating
such description.

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;All reports and other documents subsequently filed by the Company pursuant
to Sections&nbsp;13(a), 13(c), 14 and 15(d) of the Exchange Act prior to the filing
of a post-effective amendment which indicates that all securities offered have
been sold or which deregisters all securities then remaining unsold, shall be
deemed to be incorporated by reference herein and to be a part of this
registration statement from the date of the filing of such reports and
documents.

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<P align="left"><B>Item&nbsp;4. DESCRIPTION OF SECURITIES</B>

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not applicable.

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<DIV align="left"><A name="002"></A></DIV>
<P align="left"><B>Item&nbsp;5. INTERESTS OF NAMED EXPERTS AND COUNSEL</B>

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not applicable.

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<P align="left"><B>Item&nbsp;6. INDEMNIFICATION OF DIRECTORS AND OFFICERS</B>

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Registrant&#146;s Certificate of Incorporation and Bylaws include
provisions to (i)&nbsp;eliminate the personal liability of its directors for
monetary damages resulting from breaches of their fiduciary duty to the extent
permitted by Section&nbsp;102(b)(7) of the Delaware General Corporations Law
(&#147;DGCL&#148;) and (ii)&nbsp;require the Registrant to indemnify its directors and
officers to the fullest extent permitted by applicable law, including
circumstances in which indemnification is otherwise discretionary. Pursuant to
Section&nbsp;145 of the DGCL, a corporation generally has the power to indemnify its
present and former directors, officers, employees and agents against expenses
incurred by them in connection with any suit to which they are, or are
threatened to be made, a party by reason of their serving in such positions so
long as they acted in good faith and in a manner they reasonably believed to be
in, or not opposed to, the best interests of the corporation and with respect
to any criminal action, they had no reasonable cause to believe their
<P align="center">3.
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<P>conduct was unlawful. The Registrant believes that these provisions are
necessary to attract and retain qualified persons as directors and officers.
These provisions do not eliminate the directors&#146; or officers&#146; duty of care,
and, in appropriate circumstances, equitable remedies such as injunctive or
other forms of non-monetary relief will remain available under the DGCL. In
addition, each director will continue to be subject to liability pursuant to
Section&nbsp;174 of the DGCL, for breach of the director&#146;s duty of loyalty to the
Registrant, for acts or omissions not in good faith or involving intentional
misconduct, for knowing violations of law, for acts or omissions that the
director believes to be contrary to the best interests of the Registrant or its
stockholders, for any transaction from which the director derived an improper
personal benefit, for acts or omissions involving a reckless disregard for the
director&#146;s duty to the Registrant or its stockholders when the director was
aware or should have been aware of a risk of serious injury to the Registrant
or its stockholders, for acts or omission that constitute an unexcused pattern
of inattention that amounts to an abdication of the director&#146;s duty to the
Registrant or its stockholders, for improper transactions between the director
and the Registrant and for improper loans to directors and officers. The
provision also does not affect a director&#146;s responsibilities under any other
law, such as the federal securities law or state or federal environmental laws.

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Registrant has entered into indemnity agreements with each of its
directors and executive officers that require the Registrant to indemnify such
persons against expenses, judgments, fines, settlements and other amounts
incurred (including expenses of a derivative action) in connection with any
proceeding, whether actual or threatened, to which any such person may be made
a party by reason of the fact that such person is or was a director or an
executive officer of the Registrant or any of its affiliated enterprises,
provided such person acted in good faith and in a manner such person reasonably
believed to be in or not opposed to the best interests of the Registrant and,
with respect to any criminal proceeding, had no reasonable cause to believe his
conduct was unlawful. The indemnification agreements also set forth certain
procedures that will apply in the event of a claim for indemnification
thereunder.

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;At present, there is no pending litigation or proceeding involving a
director or officer of the Registrant as to which indemnification is being
sought nor is the Registrant aware of any threatened litigation that may result
in claims for indemnification by any officer or director.

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Registrant has an insurance policy covering the officers and directors
of the Registrant with respect to certain liabilities, including liabilities
arising under the Securities Act or otherwise.

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<P align="left"><B>Item&nbsp;7. EXEMPTION FROM REGISTRATION CLAIMED</B>

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not applicable.

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<P align="left"><B>Item&nbsp;8. EXHIBITS</B>

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        <TD width="8%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
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<TR valign="bottom">
        <TD nowrap align="center"><FONT size="2"><B>EXHIBIT</B></FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><FONT size="2"><B>NUMBER</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center"><FONT size="2"><B>DESCRIPTION</B></FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><HR size="1"></TD>
        <TD></TD>
        <TD nowrap align="center"><HR size="1"></TD>
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<TR valign="bottom">
        <TD valign="top"><FONT size="3">5.1</FONT></TD>
        <TD></TD>
        <TD  align="left" valign="top"><FONT size="3">
Opinion of Cooley Godward LLP</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="3">23.1</FONT></TD>
        <TD></TD>
        <TD  align="left" valign="top"><FONT size="3">
Consent of Ernst &#38; Young LLP, Independent Auditors</FONT></TD>
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<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="3">23.2</FONT></TD>
        <TD></TD>
        <TD  align="left" valign="top"><FONT size="3">
Consent of Cooley Godward LLP is contained in Exhibit&nbsp;5.1
to this Registration Statement</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="3">24.1</FONT></TD>
        <TD></TD>
        <TD  align="left" valign="top"><FONT size="3">
Power of Attorney is contained on the signature pages</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="3">99.1</FONT></TD>
        <TD></TD>
        <TD  align="left" valign="top"><FONT size="3">
1993 Stock Option Plan of PanVera Corporation</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="3">99.2</FONT></TD>
        <TD></TD>
        <TD  align="left" valign="top"><FONT size="3">
Form of Incentive Stock Option Agreement used in connection
with the 1993 Stock</FONT></TD>
</TR>
</TABLE>
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<P align="center">4.
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<TR valign="bottom">
        <TD nowrap align="center"><FONT size="2"><B>EXHIBIT</B></FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><FONT size="2"><B>NUMBER</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center"><FONT size="2"><B>DESCRIPTION</B></FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><HR size="1"></TD>
        <TD></TD>
        <TD nowrap align="center"><HR size="1"></TD>
</TR>

<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"></TD>
        <TD></TD>
        <TD  align="left" valign="top"><FONT size="3">
Option Plan of PanVera Corporation</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="3">99.3</FONT></TD>
        <TD></TD>
        <TD  align="left" valign="top"><FONT size="3">
Form of 2000 Nonstatutory Stock Option Agreement used in
connection with the 1993 Stock Option Plan of PanVera
Corporation</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="3">99.4</FONT></TD>
        <TD></TD>
        <TD  align="left" valign="top"><FONT size="3">
Form of 1993 Nonstatutory Stock Option Agreement used in
connection with the 1993 Stock Option Plan of PanVera
Corporation</FONT></TD>
</TR>
</TABLE>
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<P align="left"><B>Item&nbsp;9. UNDERTAKINGS</B>

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<B>1.&nbsp;</B>The undersigned registrant hereby undertakes:

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<B>(a)&nbsp;</B>To file, during any period in which offers or sales are being made, a
post-effective amendment to this registration statement:

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<B>(i)&nbsp;</B>To include any prospectus required by section 10(a)(3) of the
Securities Act;

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<B>(ii)&nbsp;</B>To reflect in the prospectus any facts or events arising after the
effective date of the registration statement (or the most recent post-effective
amendment thereof) which, individually or in the aggregate, represent a
fundamental change in the information set forth in the registration statement.
Notwithstanding the foregoing, any increase or decrease in volume of securities
offered (if the total dollar value of securities offered would not exceed that
which was registered) and any deviation from the low or high end of the
estimated maximum offering range may be reflected in the form of prospectus
filed with the Commission pursuant to Rule&nbsp;424(b) (Section&nbsp;230.424(b) of this
chapter) if, in the aggregate, the changes in volume and price represent no
more than a 20% change in the maximum aggregate offering price set forth in the
&#147;Calculation of Registration Fee&#148; table in the effective registration
statement.

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<B>(iii)&nbsp;</B>To include any material information with respect to the plan of
distribution not previously disclosed in the registration statement or any
material change to such information in the registration statement;

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Provided, however, that paragraphs (a)(i) and (a)(ii) do not apply if the
information required to be included in a post-effective amendment by those
paragraphs is contained in periodic reports filed by the issuer pursuant to
section 13 or section 15(d) of the Exchange Act that are incorporated by
reference herein.

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<B>(b)&nbsp;</B>That, for the purpose of determining any liability under the
Securities Act, each such post-effective amendment shall be deemed to be a new
registration statement relating to the securities offered herein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<B>(c)&nbsp;</B>To remove from registration by means of a post-effective amendment any
of the securities being registered which remain unsold at the termination of
the offering.

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<B>2.&nbsp;</B>The undersigned registrant hereby undertakes that, for purposes of
determining any liability under the Securities Act, each filing of the
registrant&#146;s annual report pursuant to Section&nbsp;13(a) or Section&nbsp;15(d) of the
Exchange Act (and, where applicable, each filing of an employee benefit plan&#146;s
annual report pursuant to section 15(d) of the Exchange Act) that is
incorporated by reference in the
<P align="center">5.
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<P>Registration Statement shall be deemed to be a new registration statement
relating to the securities offered herein, and the offering of such securities
at that time shall be deemed to be the initial bona fide offering thereof.

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<B>3.&nbsp;</B>Insofar as indemnification for liabilities arising under the Securities
Act may be permitted to directors, officers and controlling persons of the
registrant pursuant to the foregoing provisions, or otherwise, the registrant
has been advised that in the opinion of the Securities and Exchange Commission
such indemnification is against public policy as expressed in the Securities
Act and is, therefore, unenforceable. In the event that a claim for
indemnification against such liabilities (other than the payment by the
registrant of expenses incurred or paid by a director, officer or controlling
person of the registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the registrant will, unless in
the opinion of its counsel the matter has been settled by controlling
precedent, submit to a court of appropriate jurisdiction the question whether
such indemnification by it is against public policy as expressed in the
Securities Act and will be governed by the final adjudication of such issue.

<P align="center">6.
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<!-- link1 "SIGNATURES" -->
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<DIV align="left"><A name="007"></A></DIV>
<P align="center"><B>SIGNATURES</B>

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act, the Registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form&nbsp;S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of San Diego, State of California, on April 4,
2001.


<P>
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR valign="top">
        <TD width="45%">&nbsp;</TD>
        <TD width="55%"><B>AURORA BIOSCIENCES CORPORATION</B></TD>
</TR>
</TABLE>



<P>
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR valign="top">
        <TD width="45%">&nbsp;</TD>
        <TD width="5%">By:</TD>
        <TD width="50%">/s/&nbsp;&nbsp;&nbsp;STUART J. M. COLLINSON<BR><HR size="1">
Stuart J. M. Collinson<BR>
Chairman of the Board, Chief Executive Officer and<BR>
President</TD>
</TR>
</TABLE>


<P align="center"><B>POWER OF ATTORNEY</B>

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature
appears below constitutes and appoints Stuart J. M. Collinson and John R.
Pashkowsky, and both or either of them, his true and lawful attorney-in-fact
and agent, with full power of substitution and resubstitution, for him and in
his name, place and stead, in any and all capacities, to sign any and all
amendments (including post-effective amendments) to this Registration
Statement, and to file the same, with all exhibits thereto, and other documents
in connection therewith, with the Securities and Exchange Commission, granting
unto said attorneys-in-fact and agents, and each of them, full power and
authority to do and perform each and every act and thing requisite and
necessary to be done in connection therewith, as fully to all intents and
purposes as he might or could do in person, hereby ratifying and confirming all
that said attorneys-in-fact and agents, or either of them, or their or his
substitutes or substitute, may lawfully do or cause to be done by virtue
hereof.

<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act, this Registration
Statement has been signed by the following persons in the capacities and on the
dates indicated.

<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="100%" align="center">
<TR valign="bottom">
        <TD width="36%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="40%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="14%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><FONT size="2"><B>SIGNATURE</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center"><FONT size="2"><B>TITLE</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center"><FONT size="2"><B>DATE</B></FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><HR size="1"></TD>
        <TD></TD>
        <TD nowrap align="center"><HR size="1"></TD>
        <TD></TD>
        <TD nowrap align="center"><HR size="1"></TD>
</TR>

<TR>
        <TD><FONT size="3">&nbsp;</FONT></TD>
</TR>


<TR><TD align="center" valign="top"><FONT size="3">/S/&nbsp;&nbsp;&nbsp;STUART
J.M. COLLINSON<BR><HR size="1">STUART J.M. COLLINSON</FONT></TD>
        <TD><FONT size="3">&nbsp;</FONT></TD>
        <TD  align="center" valign="top"><FONT size="3">
Chairman of the Board,<BR>
Chief Executive Officer,<BR>
President and Director<BR>
(Principal Executive Officer)</FONT></TD>
        <TD><FONT size="3">&nbsp;</FONT></TD>
        <TD  align="center" valign="top"><FONT size="3">April 4, 2001</FONT></TD>
</TR>

<TR>
<TD><FONT size="3">&nbsp;</FONT></TD>
</TR>

<TR><TR><TD align="center" valign="top"><FONT size="3">/S/&nbsp;&nbsp;&nbsp;JOHN
R. PASHKOWSKY<BR><HR size="1">JOHN R. PASHKOWSKY</FONT></TD>
        <TD><FONT size="3">&nbsp;</FONT></TD>
        <TD  align="center" valign="top"><FONT size="3">
Vice President of Finance and<BR>
Treasurer (Principal Financial<BR>
and Accounting Officer)</FONT></TD>
<TD><FONT size="3">&nbsp;</FONT></TD>
        <TD  align="center" valign="top"><FONT size="3">April 4,
2001</FONT></TD>
</TR>

<TR>
<TD><FONT size="3">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD align="center" valign="top"><FONT size="3">/S/&nbsp;&nbsp;&nbsp;JAMES
C. BLAIR<BR><HR size="1">JAMES C. BLAIR</FONT></TD>
        <TD><FONT size="3">&nbsp;</FONT></TD>

<TD  align="center" valign="top"><FONT size="3">Director</FONT></TD>
        <TD><FONT size="3">&nbsp;</FONT></TD>
        <TD  align="center" valign="top"><FONT size="3">April 4,
2001</FONT></TD>
</TR>

<TR>
        <TD><FONT size="3">&nbsp;</FONT></TD></TR>
</TR>

<TR>

        <TD align="center" valign="top"><FONT size="3">&nbsp;<BR>
        <HR size="1">JOHN D. MENDLEIN</FONT></TD>
        <TD><FONT size="3">&nbsp;</FONT></TD>
        <TD  align="center" valign="top"><FONT size="3">Director</FONT></TD>
        <TD><FONT size="3">&nbsp;</FONT></TD>
        <TD align="center" valign="top"><FONT size="3">April &nbsp;,
2001</FONT></TD>
</TR>

<TR>

<TD align="center" valign="top"><FONT size="3">&nbsp;</FONT></TD>
</TR>

<TR><TD align="center"><FONT size="3">/S/&nbsp;&nbsp;&nbsp;HUGH Y. RIENHOFF, JR<BR><HR size="1">
HUGH Y. RIENHOFF, JR</FONT></TD>
        <TD><FONT size="3">&nbsp;</FONT></TD>

<TD  align="center" valign="top"><FONT size="3">Director</FONT></TD>
        <TD><FONT size="3">&nbsp;</FONT></TD>
        <TD  align="center" valign="top"><FONT size="3">April 4, 2001</FONT></TD>
</TR>
</TABLE>
</CENTER>
<P align="center">7.
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<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="100%" align="center">
<TR valign="bottom">
        <TD width="36%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="40%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="14%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><FONT size="2"><B>SIGNATURE</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center"><FONT size="2"><B>TITLE</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center"><FONT size="2"><B>DATE</B></FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><HR size="1"></TD>
        <TD></TD>
        <TD nowrap align="center"><HR size="1"></TD>
        <TD></TD>
        <TD nowrap align="center"><HR size="1"></TD>
</TR>

<TR>
        <TD><FONT size="3">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD align="center" valign="bottom"><FONT size="3">/S/&nbsp;&nbsp;&nbsp;ROY A. WHITFIELD<BR><HR size="1">ROY A. WHITFIELD</FONT></TD>
        <TD><FONT size="3">&nbsp;</FONT></TD>
        <TD  align="center" valign="top"><FONT size="3">
Director</FONT></TD>
        <TD><FONT size="3">&nbsp;</FONT></TD>
        <TD  align="center" valign="top"><FONT size="3">April 4,
2001</FONT></TD>
</TR>

<TR>
        <TD><FONT size="3">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD align="center" valign="bottom"><FONT size="3">/S/&nbsp;&nbsp;&nbsp;WENDELL WIERENGA<BR><HR size="1">WENDELL WIERENGA</FONT></TD>
        <TD><FONT size="3">&nbsp;</FONT></TD>
        <TD  align="center" valign="top"><FONT size="3">
Director</FONT></TD>
        <TD><FONT size="3">&nbsp;</FONT></TD>
        <TD  align="center" valign="top"><FONT size="3">April 4,
2001</FONT></TD>
</TR>


<TR>
<TD><FONT size="3">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD align="center" valign="bottom"><FONT size="3">/S/&nbsp;&nbsp;&nbsp;TIMOTHY J. WOLLAEGER<BR><HR size="1">TIMOTHY J. WOLLAEGER</FONT></TD>
        <TD><FONT size="3">&nbsp;</FONT></TD>
        <TD  align="center" valign="top"><FONT size="3">
Director</FONT></TD>
        <TD><FONT size="3">&nbsp;</FONT></TD>
        <TD  align="center" valign="top"><FONT size="3">April 4,
2001</FONT></TD>
</TR>


</TABLE>
</CENTER>
<P align="center">8.
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<!-- link1 "EXHIBIT INDEX" -->
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<DIV align="left"><A name="008"></A></DIV>
<P align="center"><B>EXHIBIT INDEX</B>

<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="100%" align="center">
<TR valign="bottom">
        <TD width="8%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="87%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><FONT size="2"><B>EXHIBIT</B></FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><FONT size="2"><B>NUMBER</B></FONT></TD>
        <TD></TD>
        <TD nowrap align="center"><FONT size="2"><B>DESCRIPTION</B></FONT></TD>
</TR>
<TR valign="bottom">
        <TD nowrap align="center"><HR size="1"></TD>
        <TD></TD>
        <TD nowrap align="center"><HR size="1"></TD>
</TR>

<TR valign="bottom">
        <TD align="left" valign="top"><FONT size="3">5.1</FONT></TD>
        <TD></TD>
        <TD  align="left" valign="top"><FONT size="3">
Opinion of Cooley Godward LLP</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="3">23.1</FONT></TD>
        <TD></TD>
        <TD  align="left" valign="top"><FONT size="3">
Consent of Ernst &#38; Young LLP, Independent Auditors</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="3">23.2</FONT></TD>
        <TD></TD>
        <TD  align="left" valign="top"><FONT size="3">
Consent of Cooley Godward LLP is contained in Exhibit&nbsp;5.1
to this Registration Statement</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="3">24.1</FONT></TD>
        <TD></TD>
        <TD  align="left" valign="top"><FONT size="3">
Power of Attorney is contained on the signature pages</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="3">99.1</FONT></TD>
        <TD></TD>
        <TD  align="left" valign="top"><FONT size="3">
1993 Stock Option Plan of PanVera Corporation</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="3">99.2</FONT></TD>
        <TD></TD>
        <TD  align="left" valign="top"><FONT size="3">
Form of Incentive Stock Option Agreement used in connection
with the 1993 Stock Option Plan of PanVera Corporation</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="3">99.3</FONT></TD>
        <TD></TD>
        <TD  align="left" valign="top"><FONT size="3">
Form of 2000 Nonstatutory Stock Option Agreement used in
connection with the 1993 Stock Option Plan of PanVera
Corporation</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="bottom">
        <TD valign="top"><FONT size="3">99.4</FONT></TD>
        <TD></TD>
        <TD  align="left" valign="top"><FONT size="3">
Form of 1993 Nonstatutory Stock Option Agreement used in
connection with the 1993 Stock Option Plan of PanVera
Corporation</FONT></TD>
</TR>
</TABLE>
</CENTER>

<P align="center">9.
</BODY>
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s-8
Table of Contents
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
Form S-8
REGISTRATION STATEMENT
Under
THE SECURITIES ACT OF 1933
AURORA BIOSCIENCES CORPORATION
(Exact Name Of Registrant As Specified In Its Charter)
Delaware
(State or Other Jurisdiction of
Incorporation or Organization)
33-0669859
(I.R.S. Employer Identification No.)
11010 Torreyana Road
San Diego, California 92121
(858) 404-6600
(Address, Including Zip Code, and Telephone Number, Including Area Code, of Registrant's Principal Executive Offices)
1993 STOCK OPTION PLAN OF PANVERA CORPORATION
(Full Title of the Plan)
Stuart J. M. Collinson
Chairman, Chief Executive Officer and President
AURORA BIOSCIENCES CORPORATION
11010 Torreyana Road
San Diego, California 92121
(858) 404-6600
(Name, Address, Including Zip Code, and Telephone Number, Including Area Code, of Agent for Service)
Copies to
:
Thomas A. Coll, Esq.
COOLEY GODWARD LLP
4365 Executive Drive, Suite 1100
San Diego, California 92121
(858) 550-6000
CALCULATION OF REGISTRATION FEE
Proposed
Proposed
Title of
maximum
maximum
Securities to be
Amount to be
offering price per
aggregate
Amount of
registered (1)
registered (1)
share (2)
offering price (2)
registration fee (2)
Common Stock,
$0.001 par value
260,222
See note 2
See note 2
See note 2
(1)
On March 1, 2001, the Registrant completed the acquisition of PanVera
Corporation, a Wisconsin corporation ("PanVera"). In connection with the
acquisition, the Registrant assumed the obligations under the 1993 Stock
Option Plan of PanVera Corporation (the "Plan"). The Registrant does not
anticipate issuing any additional stock options under the Plan. The
number of shares being registered represents the aggregate number of
options to purchase shares of the Registrant's Common Stock assumed in
connection with the acquisition.
(2)
Pursuant to Rule 429, the Registrant prepaid the registration fee for the
entire 260,222 shares under the Plan when it registered up to 1,900,000
shares of Common Stock pursuant to a Registration Statement on Form S-4
(File Number 333-54638) filed on January 30, 2001.
TABLE OF CONTENTS
Item 3. INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE
Item 4. DESCRIPTION OF SECURITIES
Item 5. INTERESTS OF NAMED EXPERTS AND COUNSEL
Item 6. INDEMNIFICATION OF DIRECTORS AND OFFICERS
Item 7. EXEMPTION FROM REGISTRATION CLAIMED
Item 8. EXHIBITS
Item 9. UNDERTAKINGS
SIGNATURES
EXHIBIT INDEX
EXHIBIT 5.1
EXHIBIT 23.1
EXHIBIT 99.1
EXHIBIT 99.2
EXHIBIT 99.3
EXHIBIT 99.4
Item 3. INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE
The following documents filed by AURORA BIOSCIENCES CORPORATION (the
"Company") with the Securities and Exchange Commission are incorporated by
reference into this Registration Statement:
(a) The Company's annual report on Form 10-K for the year ended December
31, 2000.
(b) All other reports filed pursuant to Sections 13(a) or 15(d) of the
Securities Exchange Act of 1934, as amended (the "Exchange Act") since the end
of the fiscal year covered by the annual report referred to in (a) above.
(c) The description of the Company's Common Stock which is contained in a
registration statement on Form S-1 filed on March 14, 1997 (Registration No.
33-23407), including any amendment or report filed for the purposes of updating
such description.
All reports and other documents subsequently filed by the Company pursuant
to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act prior to the filing
of a post-effective amendment which indicates that all securities offered have
been sold or which deregisters all securities then remaining unsold, shall be
deemed to be incorporated by reference herein and to be a part of this
registration statement from the date of the filing of such reports and
documents.
Item 4. DESCRIPTION OF SECURITIES
Not applicable.
Item 5. INTERESTS OF NAMED EXPERTS AND COUNSEL
Not applicable.
Item 6. INDEMNIFICATION OF DIRECTORS AND OFFICERS
The Registrant's Certificate of Incorporation and Bylaws include
provisions to (i) eliminate the personal liability of its directors for
monetary damages resulting from breaches of their fiduciary duty to the extent
permitted by Section 102(b)(7) of the Delaware General Corporations Law
("DGCL") and (ii) require the Registrant to indemnify its directors and
officers to the fullest extent permitted by applicable law, including
circumstances in which indemnification is otherwise discretionary. Pursuant to
Section 145 of the DGCL, a corporation generally has the power to indemnify its
present and former directors, officers, employees and agents against expenses
incurred by them in connection with any suit to which they are, or are
threatened to be made, a party by reason of their serving in such positions so
long as they acted in good faith and in a manner they reasonably believed to be
in, or not opposed to, the best interests of the corporation and with respect
to any criminal action, they had no reasonable cause to believe their
3.
Table of Contents
conduct was unlawful. The Registrant believes that these provisions are
necessary to attract and retain qualified persons as directors and officers.
These provisions do not eliminate the directors' or officers' duty of care,
and, in appropriate circumstances, equitable remedies such as injunctive or
other forms of non-monetary relief will remain available under the DGCL. In
addition, each director will continue to be subject to liability pursuant to
Section 174 of the DGCL, for breach of the director's duty of loyalty to the
Registrant, for acts or omissions not in good faith or involving intentional
misconduct, for knowing violations of law, for acts or omissions that the
director believes to be contrary to the best interests of the Registrant or its
stockholders, for any transaction from which the director derived an improper
personal benefit, for acts or omissions involving a reckless disregard for the
director's duty to the Registrant or its stockholders when the director was
aware or should have been aware of a risk of serious injury to the Registrant
or its stockholders, for acts or omission that constitute an unexcused pattern
of inattention that amounts to an abdication of the director's duty to the
Registrant or its stockholders, for improper transactions between the director
and the Registrant and for improper loans to directors and officers. The
provision also does not affect a director's responsibilities under any other
law, such as the federal securities law or state or federal environmental laws.
The Registrant has entered into indemnity agreements with each of its
directors and executive officers that require the Registrant to indemnify such
persons against expenses, judgments, fines, settlements and other amounts
incurred (including expenses of a derivative action) in connection with any
proceeding, whether actual or threatened, to which any such person may be made
a party by reason of the fact that such person is or was a director or an
executive officer of the Registrant or any of its affiliated enterprises,
provided such person acted in good faith and in a manner such person reasonably
believed to be in or not opposed to the best interests of the Registrant and,
with respect to any criminal proceeding, had no reasonable cause to believe his
conduct was unlawful. The indemnification agreements also set forth certain
procedures that will apply in the event of a claim for indemnification
thereunder.
At present, there is no pending litigation or proceeding involving a
director or officer of the Registrant as to which indemnification is being
sought nor is the Registrant aware of any threatened litigation that may result
in claims for indemnification by any officer or director.
The Registrant has an insurance policy covering the officers and directors
of the Registrant with respect to certain liabilities, including liabilities
arising under the Securities Act or otherwise.
Item 7. EXEMPTION FROM REGISTRATION CLAIMED
Not applicable.
Item 8. EXHIBITS
EXHIBIT
NUMBER
DESCRIPTION
5.1
Opinion of Cooley Godward LLP
23.1
Consent of Ernst & Young LLP, Independent Auditors
23.2
Consent of Cooley Godward LLP is contained in Exhibit 5.1
to this Registration Statement
24.1
Power of Attorney is contained on the signature pages
99.1
1993 Stock Option Plan of PanVera Corporation
99.2
Form of Incentive Stock Option Agreement used in connection
with the 1993 Stock
4.
Table of Contents
EXHIBIT
NUMBER
DESCRIPTION
Option Plan of PanVera Corporation
99.3
Form of 2000 Nonstatutory Stock Option Agreement used in
connection with the 1993 Stock Option Plan of PanVera
Corporation
99.4
Form of 1993 Nonstatutory Stock Option Agreement used in
connection with the 1993 Stock Option Plan of PanVera
Corporation
Item 9. UNDERTAKINGS
1.
The undersigned registrant hereby undertakes:
(a)
To file, during any period in which offers or sales are being made, a
post-effective amendment to this registration statement:
(i)
To include any prospectus required by section 10(a)(3) of the
Securities Act;
(ii)
To reflect in the prospectus any facts or events arising after the
effective date of the registration statement (or the most recent post-effective
amendment thereof) which, individually or in the aggregate, represent a
fundamental change in the information set forth in the registration statement.
Notwithstanding the foregoing, any increase or decrease in volume of securities
offered (if the total dollar value of securities offered would not exceed that
which was registered) and any deviation from the low or high end of the
estimated maximum offering range may be reflected in the form of prospectus
filed with the Commission pursuant to Rule 424(b) (Section 230.424(b) of this
chapter) if, in the aggregate, the changes in volume and price represent no
more than a 20% change in the maximum aggregate offering price set forth in the
"Calculation of Registration Fee" table in the effective registration
statement.
(iii)
To include any material information with respect to the plan of
distribution not previously disclosed in the registration statement or any
material change to such information in the registration statement;
Provided, however, that paragraphs (a)(i) and (a)(ii) do not apply if the
information required to be included in a post-effective amendment by those
paragraphs is contained in periodic reports filed by the issuer pursuant to
section 13 or section 15(d) of the Exchange Act that are incorporated by
reference herein.
(b)
That, for the purpose of determining any liability under the
Securities Act, each such post-effective amendment shall be deemed to be a new
registration statement relating to the securities offered herein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.
(c)
To remove from registration by means of a post-effective amendment any
of the securities being registered which remain unsold at the termination of
the offering.
2.
The undersigned registrant hereby undertakes that, for purposes of
determining any liability under the Securities Act, each filing of the
registrant's annual report pursuant to Section 13(a) or Section 15(d) of the
Exchange Act (and, where applicable, each filing of an employee benefit plan's
annual report pursuant to section 15(d) of the Exchange Act) that is
incorporated by reference in the
5.
Table of Contents
Registration Statement shall be deemed to be a new registration statement
relating to the securities offered herein, and the offering of such securities
at that time shall be deemed to be the initial bona fide offering thereof.
3.
Insofar as indemnification for liabilities arising under the Securities
Act may be permitted to directors, officers and controlling persons of the
registrant pursuant to the foregoing provisions, or otherwise, the registrant
has been advised that in the opinion of the Securities and Exchange Commission
such indemnification is against public policy as expressed in the Securities
Act and is, therefore, unenforceable. In the event that a claim for
indemnification against such liabilities (other than the payment by the
registrant of expenses incurred or paid by a director, officer or controlling
person of the registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the registrant will, unless in
the opinion of its counsel the matter has been settled by controlling
precedent, submit to a court of appropriate jurisdiction the question whether
such indemnification by it is against public policy as expressed in the
Securities Act and will be governed by the final adjudication of such issue.
6.
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SIGNATURES
Pursuant to the requirements of the Securities Act, the Registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of San Diego, State of California, on April 4,
2001.
AURORA BIOSCIENCES CORPORATION
By:
/s/   STUART J. M. COLLINSON
Stuart J. M. Collinson
Chairman of the Board, Chief Executive Officer and
President
POWER OF ATTORNEY
KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature
appears below constitutes and appoints Stuart J. M. Collinson and John R.
Pashkowsky, and both or either of them, his true and lawful attorney-in-fact
and agent, with full power of substitution and resubstitution, for him and in
his name, place and stead, in any and all capacities, to sign any and all
amendments (including post-effective amendments) to this Registration
Statement, and to file the same, with all exhibits thereto, and other documents
in connection therewith, with the Securities and Exchange Commission, granting
unto said attorneys-in-fact and agents, and each of them, full power and
authority to do and perform each and every act and thing requisite and
necessary to be done in connection therewith, as fully to all intents and
purposes as he might or could do in person, hereby ratifying and confirming all
that said attorneys-in-fact and agents, or either of them, or their or his
substitutes or substitute, may lawfully do or cause to be done by virtue
hereof.
Pursuant to the requirements of the Securities Act, this Registration
Statement has been signed by the following persons in the capacities and on the
dates indicated.
SIGNATURE
TITLE
DATE
/S/   STUART
J.M. COLLINSON
STUART J.M. COLLINSON
Chairman of the Board,
Chief Executive Officer,
President and Director
(Principal Executive Officer)
April 4, 2001
/S/   JOHN
R. PASHKOWSKY
JOHN R. PASHKOWSKY
Vice President of Finance and
Treasurer (Principal Financial
and Accounting Officer)
April 4,
2001
/S/   JAMES
C. BLAIR
JAMES C. BLAIR
Director
April 4,
2001
JOHN D. MENDLEIN
Director
April  ,
2001
/S/   HUGH Y. RIENHOFF, JR
HUGH Y. RIENHOFF, JR
Director
April 4, 2001
7.
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SIGNATURE
TITLE
DATE
/S/   ROY A. WHITFIELD
ROY A. WHITFIELD
Director
April 4,
2001
/S/   WENDELL WIERENGA
WENDELL WIERENGA
Director
April 4,
2001
/S/   TIMOTHY J. WOLLAEGER
TIMOTHY J. WOLLAEGER
Director
April 4,
2001
8.
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EXHIBIT INDEX
EXHIBIT
NUMBER
DESCRIPTION
5.1
Opinion of Cooley Godward LLP
23.1
Consent of Ernst & Young LLP, Independent Auditors
23.2
Consent of Cooley Godward LLP is contained in Exhibit 5.1
to this Registration Statement
24.1
Power of Attorney is contained on the signature pages
99.1
1993 Stock Option Plan of PanVera Corporation
99.2
Form of Incentive Stock Option Agreement used in connection
with the 1993 Stock Option Plan of PanVera Corporation
99.3
Form of 2000 Nonstatutory Stock Option Agreement used in
connection with the 1993 Stock Option Plan of PanVera
Corporation
99.4
Form of 1993 Nonstatutory Stock Option Agreement used in
connection with the 1993 Stock Option Plan of PanVera
Corporation
9.