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<TITLE>Neorx Corp. Form S-8</TITLE>
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<P align="center"><FONT size="2"><B>As filed with the Securities and Exchange Commission on October&nbsp;10, 2001</B></FONT>
<div>

  <div align="right"><FONT size="2"><B>Registration No.&nbsp;333-</B></FONT> </div>
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<P align="center"><FONT size="2"><B>SECURITIES AND EXCHANGE COMMISSION<BR>
  Washington, D.C. 20549</B></FONT>
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<div align="center"><FONT size="2"><B>FORM S-8<br>
  </B></FONT><FONT size="2"><B>REGISTRATION STATEMENT<br>
  </B></FONT><FONT size="2"><B>UNDER<br>
  </B></FONT><FONT size="2"><B>THE SECURITIES ACT OF 1933</B></FONT> </div>
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<div align="center"><FONT size="2"><B>NEORX CORPORATION</B><BR>
  <font size="1">(Exact name of registrant as specified in its charter)</font></FONT>
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        <TD width="45%">&nbsp;</TD>
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          <TD valign="top">
        <div align="center"><FONT size="2"><B>Washington</B> <br>
          <font size="1">(State of other jurisdiction of incorporation or organization)</font></FONT></div>
      </TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
          <TD align="left" valign="top">
        <div align="center"><FONT size="2"> <B>91-1261311<br>
          </B> <font size="1">(I.R.S. Employer Identification No.)</font></FONT></div>
      </TD>
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</TABLE>
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<P align="center"><FONT size="2"><B>410 West Harrison Street<BR>
Seattle, Washington 98119</B><BR>
  <font size="1">(Address of principal executive offices, including zip code)</font></FONT>
<P align="center"><FONT size="2"><B>NEORX CORPORATION RESTATED 1994 STOCK OPTION PLAN<BR>
STOCK OPTION AGREEMENT DATED JULY 30, 2001</B><BR>
<FONT size="1">(Full title of the plans)</FONT>

<P align="center"><FONT size="2"><B>RICHARD L. ANDERSON<BR>
  Chief Financial Officer and Senior Vice President<BR>
  NeoRx Corporation<BR>
  410 West Harrison Street<BR>
  Seattle, Washington 98119<BR>
  (206)&nbsp;286-2518</B><BR>
  <font size="1">(Name, address and telephone number, including area code, of
  agent for service)</font></FONT>
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<div align="center"><FONT size="2"><B>Copy to:</B></FONT> </div>
<P align="center"><FONT size="2"><B>JAMES R. LISBAKKEN<br>
  </B></FONT><FONT size="2"><B>Perkins Coie LLP<BR>
  1201 Third Avenue, Suite&nbsp;4800<BR>
  Seattle, Washington 98101-3099<BR>
  (206)&nbsp;583-8888</B></FONT>
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<div align="center"><FONT size="2"><B>CALCULATION OF REGISTRATION FEE</B></FONT>
</div>
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  <TABLE cellspacing="0" border="0" cellpadding="0" width="100%">
    <TR valign="bottom">
      <TD colspan="19">
        <hr size="4" noshade>
      </TD>
    </TR>
    <TR valign="bottom">
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD nowrap align="center" colspan="3"><FONT size="1"><B>Proposed Maximum</B></FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD nowrap align="center" colspan="3"><FONT size="1"><B>Proposed Maximum</B></FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD nowrap align="center" colspan="3"><FONT size="1"><B>Amount to Be</B></FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD nowrap align="center" colspan="3"><FONT size="1"><B>Offering Price Per</B></FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD nowrap align="center" colspan="3"><FONT size="1"><B>Aggregate Offering</B></FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD nowrap align="center" colspan="3"><FONT size="1"><B>Amount of</B></FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD nowrap align="center" colspan="3"><FONT size="1"><B>Title of Securities
        to be Registered</B></FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD nowrap align="center" colspan="3"><FONT size="1"><B>Registered (1)</B></FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD nowrap align="center" colspan="3"><FONT size="1"><B>Share</B></FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD nowrap align="center" colspan="3"><FONT size="1"><B>Price</B></FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD nowrap align="center" colspan="3"><FONT size="1"><B>Registration Fee</B></FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD colspan="19">
        <HR size="1" noshade>
      </TD>
    </TR>
    <TR valign="bottom">
      <TD colspan="3">
        <DIV style="margin-left:10px; text-indent:-10px"><FONT size="2">Common
          Stock, par value $0.02 per share, under the:</FONT></DIV>
      </TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD colspan="2">
        <DIV style="margin-left:10px; text-indent:-10px"><FONT size="2">Restated
          1994 Stock Option Plan</FONT></DIV>
      </TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="right"><FONT size="2">1,300,000</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD nowrap align="right"><FONT size="2">$</FONT></TD>
      <TD align="right"><FONT size="2">3.22</FONT></TD>
      <TD nowrap><FONT size="2">(2)</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="right"><FONT size="2">$</FONT></TD>
      <TD align="right"><FONT size="2">4,186,000</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD nowrap align="right"><FONT size="2">$</FONT></TD>
      <TD align="right"><FONT size="2">1,046.50</FONT></TD>
      <TD nowrap><FONT size="2">(2)</FONT></TD>
    </TR>
    <TR>
      <TD colspan="19">

        <HR size="1" noshade>
      </TD>
    </TR>
    <TR valign="bottom">
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD colspan="2">
        <DIV style="margin-left:10px; text-indent:-10px"><FONT size="2">Stock
          Option Agreement dated July&nbsp;30, 2001</FONT></DIV>
      </TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="right"><FONT size="2">150,000</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD nowrap align="right"><FONT size="2">$</FONT></TD>
      <TD align="right"><FONT size="2">3.35</FONT></TD>
      <TD nowrap><FONT size="2">(3)</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="right"><FONT size="2">$</FONT></TD>
      <TD align="right"><FONT size="2">502,500</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD nowrap align="right"><FONT size="2">$</FONT></TD>
      <TD align="right"><FONT size="2">125.63</FONT></TD>
      <TD nowrap><FONT size="2">(3)</FONT></TD>
    </TR>
    <TR>
      <TD colspan="19">

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      </TD>
    </TR>
    <TR valign="bottom">
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD>
        <DIV style="margin-left:10px; text-indent:-10px"><FONT size="2">TOTAL</FONT></DIV>
      </TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="right"><FONT size="2">1,450,000</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="right"><FONT size="2">$</FONT></TD>
      <TD align="right"><FONT size="2">4,688,500</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="right"><FONT size="2">$</FONT></TD>
      <TD align="right"><FONT size="2">1,172.13</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
    </TR>
    <TR>
      <TD colspan="19">

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      </TD>
    </TR>
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<P>
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<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR valign="top">
      <TD width="1%" align="left" nowrap><FONT size="2">(1)</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="96%"><FONT size="2">Together with an indeterminate number of additional shares which may be
necessary to adjust the number of shares reserved for issuance pursuant
to such employee benefit plans as the result of any future stock split,
stock dividend or similar adjustment of the Registrant&#146;s outstanding
Common Stock.</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="top">
      <TD width="1%" align="left" nowrap><FONT size="2">(2)</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="96%"><FONT size="2">Estimated solely for the purpose of calculating the registration fee
pursuant to Rule&nbsp;457(c) under the Securities Act of 1933, as amended.
The calculation of the registration fee is based upon a per share price
of $3.22, which was the average of the high ($3.38) and low ($3.06)
sales prices of the Registrant&#146;s common stock on October&nbsp;9, 2001, as
reported by the NASDAQ National Market.</FONT></TD>
</TR>
<TR><TD><TR><TD><TR><TD><TR><TD>
<TR valign="top">
      <TD width="1%" align="left" nowrap><FONT size="2">(3)</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="96%"><FONT size="2">Computed pursuant to Rule&nbsp;457(h) under the Securities Act of 1933, as
amended, based on the exercise price of the stock option issued pursuant
to the stock option agreement.</FONT></TD>
</TR>
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<A name="toc"><DIV align="CENTER"><U><B>TABLE OF CONTENTS</B></U></DIV></A>

<P><CENTER>
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<TR><TD colspan="9"><A HREF="#000">PART II INFORMATION REQUIRED IN REGISTRATION STATEMENT</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#001">Item&nbsp;3. INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#002">Item&nbsp;4. DESCRIPTION OF SECURITIES</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#003">Item&nbsp;5. INTERESTS OF NAMED EXPERTS AND COUNSEL</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#004">Item&nbsp;6. INDEMNIFICATION OF DIRECTORS AND OFFICERS</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#005">Item&nbsp;7. EXEMPTION FROM REGISTRATION CLAIMED</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#006">Item&nbsp;8. EXHIBITS</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#007">Item&nbsp;9. UNDERTAKINGS</A></TD></TR>
<TR><TD colspan="9"><A HREF="#008">SIGNATURES</A></TD></TR>
<TR><TD colspan="9"><A HREF="#009">INDEX TO EXHIBITS</A></TD></TR>
<TR><TD colspan="9"><A HREF="v76259orex5-1.txt">EXHIBIT 5.1</A></TD></TR>
<TR><TD colspan="9"><A HREF="v76259orex23-1.txt">EXHIBIT 23.1</A></TD></TR>
<TR><TD colspan="9"><A HREF="v76259orex99-1.txt">EXHIBIT 99.1</A></TD></TR>
<TR><TD colspan="9"><A HREF="v76259orex99-2.txt">EXHIBIT 99.2</A></TD></TR>
</TABLE>
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<H5 align="left"><A HREF="#toc">Table of Contents</A></H5><P>
<!-- link1 "PART II INFORMATION REQUIRED IN REGISTRATION STATEMENT" -->
<DIV align="left"><A NAME="000"></A></DIV>
<P align="center"><FONT size="2"><B>PART II</B></FONT>

<P align="center"><FONT size="2"><B>INFORMATION REQUIRED IN REGISTRATION STATEMENT</B></FONT>

<!-- link2 "Item&nbsp;3. INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE" -->
<DIV align="left"><A NAME="001"></A></DIV>
<P align="left"><FONT size="2"><B>Item&nbsp;3. INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE</B></FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The following documents filed by the Registrant with the Securities and
Exchange Commission (the &#147;Commission&#148;) are hereby incorporated by reference in
this Registration Statement:
</FONT>
<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a)&nbsp; The Registrant&#146;s Annual Report on Form&nbsp;10-K for the year ended
December&nbsp;31, 2000, filed on March&nbsp;30, 2001, which contains audited financial
statements for the most recent fiscal year for which such statements have been
filed;
</FONT>
<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b)&nbsp; The Registrant&#146;s Quarterly Reports on Form&nbsp;10-Q for the fiscal
quarters ended March&nbsp;31, 2001 and June&nbsp;30, 2001 filed on May&nbsp;14, 2001 and
August&nbsp;6, 2001, respectively;
</FONT>
<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c)&nbsp; The description of the Registrant&#146;s common stock contained in the
Registration Statement on Form&nbsp;8-A, filed on March&nbsp;21, 1988, under Section
12(g) of the Securities Exchange Act of 1934, as amended (the &#147;Exchange Act&#148;),
including any amendments or reports filed for the purpose of updating such
description; and
</FONT>
<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(d)&nbsp; All other reports filed pursuant to Section&nbsp;13(a) or 15(d) of the
Exchange Act since the end of the fiscal year covered by the Annual Report on
Form&nbsp;10-K referred to in (a)&nbsp;above.
</FONT>
<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;All documents filed by the Registrant pursuant to Sections&nbsp;13(a), 13(c),
14 and 15(d) of the Exchange Act after the date hereof, and prior to the filing
of a post-effective amendment which indicates that the securities offered
hereby have been sold or which deregisters the securities covered hereby then
remaining unsold, shall also be deemed to be incorporated by reference into
this Registration Statement and to be a part hereof commencing on the
respective dates on which such documents are filed.
</FONT>
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<DIV align="left"><A NAME="002"></A></DIV>
<P align="left"><FONT size="2"><B>Item&nbsp;4. DESCRIPTION OF SECURITIES</B></FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not applicable.
</FONT>
<!-- link2 "Item&nbsp;5. INTERESTS OF NAMED EXPERTS AND COUNSEL" -->
<DIV align="left"><A NAME="003"></A></DIV>
<P align="left"><FONT size="2"><B>Item&nbsp;5. INTERESTS OF NAMED EXPERTS AND COUNSEL</B></FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not applicable.
</FONT>
<!-- link2 "Item&nbsp;6. INDEMNIFICATION OF DIRECTORS AND OFFICERS" -->
<DIV align="left"><A NAME="004"></A></DIV>
<P align="left"><FONT size="2"><B>Item&nbsp;6. INDEMNIFICATION OF DIRECTORS AND OFFICERS</B></FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Sections&nbsp;23B.08.500 through 23B.08.600 of the Washington Business
Corporation Act authorize a court to award, or a corporation&#146;s board of
directors to grant, indemnification to directors and officers on terms
sufficiently broad to permit indemnification under certain circumstances for
liabilities arising under the Securities Act of 1933, as amended (the
&#147;Securities Act&#148;). Article&nbsp;XIII of the Registrant&#146;s Restated Articles of
Incorporation and Section&nbsp;12 of the Registrant&#146;s Bylaws provide for
indemnification of the Registrant&#146;s directors, officers, employees and agents
to the maximum extent permitted by Washington law and provide that the
directors and officers of the Registrant may also be indemnified against
liability they may incur for serving in those capacities pursuant to a
liability insurance policy maintained by the Registrant for such purpose.
</FONT>
<P align="center"><font size="2">II-1</font>
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<H5 align="left"><A HREF="#toc">Table of Contents</A></H5><P>
<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Section&nbsp;23B.08.320 of the Washington Business Corporation Act authorizes a
corporation to limit a director&#146;s liability to the corporation or its
shareholders for monetary damages for acts or omissions as a director, except
in certain circumstances involving intentional misconduct, knowing violations
of law or illegal corporate loans or distributions, or any transactions from
which the director personally receives a benefit in money, property or services
to which the director is not legally entitled. Article&nbsp;XII of the Registrant&#146;s
Restated Articles of Incorporation contains provisions implementing, to the
fullest extent permitted by Washington law, such limitations on a director&#146;s
liability to the Registrant and its shareholders.
</FONT>
<!-- link2 "Item&nbsp;7. EXEMPTION FROM REGISTRATION CLAIMED" -->
<DIV align="left"><A NAME="005"></A></DIV>
<P align="left"><FONT size="2"><B>Item&nbsp;7. EXEMPTION FROM REGISTRATION CLAIMED</B></FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not applicable.
</FONT>
<!-- link2 "Item&nbsp;8. EXHIBITS" -->
<DIV align="left"><A NAME="006"></A></DIV>
<P align="left"><FONT size="2"><B>Item&nbsp;8. EXHIBITS</B></FONT>

<CENTER>
  <TABLE cellspacing="0" border="0" cellpadding="0" width="90%">
    <TR valign="bottom">
      <TD width="8%">&nbsp;</TD>
      <TD width="5%">&nbsp;</TD>
      <TD width="87%">&nbsp;</TD>
    </TR>
    <TR valign="bottom">
      <TD nowrap align="center"><FONT size="1"><B>Exhibit No.</B></FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD nowrap align="center"><FONT size="1"><B>Description</B></FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD nowrap align="center">
        <HR size="1" noshade>
      </TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD nowrap align="center">
        <HR size="1" noshade>
      </TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">
        <div align="center"><FONT size="2">5.1</FONT></div>
      </TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="left" valign="top"><FONT size="2"> Opinion of Perkins Coie LLP
        regarding legality of the Common Stock being registered</FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">
        <div align="center"><FONT size="2">23.1</FONT></div>
      </TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="left" valign="top"><FONT size="2"> Consent of Independent Certified
        Public Accountants</FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">
        <div align="center"><FONT size="2">23.2</FONT></div>
      </TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="left" valign="top"><FONT size="2"> Consent of Perkins Coie LLP
        (included in opinion filed as Exhibit&nbsp;5.1)</FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">
        <div align="center"><FONT size="2">24.1</FONT></div>
      </TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="left" valign="top"><FONT size="2"> Power of Attorney (see signature
        page)</FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">
        <div align="center"><FONT size="2">99.1</FONT></div>
      </TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="left" valign="top"><FONT size="2"> NeoRx Corporation Restated
        1994 Stock Option Plan</FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">
        <div align="center"><FONT size="2">99.2</FONT></div>
      </TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="left" valign="top"><FONT size="2"> Stock Option Agreement dated
        July&nbsp;30, 2001</FONT></TD>
    </TR>
  </TABLE>
</CENTER>
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<DIV align="left"><A NAME="007"></A></DIV>
<P align="left"><FONT size="2"><B>Item&nbsp;9. UNDERTAKINGS</B></FONT>

<P><FONT size="2">A.&nbsp;The undersigned Registrant hereby undertakes:
</FONT>
<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1)&nbsp; To file, during any period in which offers or sales are being made, a
post-effective amendment to this Registration Statement:
</FONT>
<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(i)&nbsp;To include any prospectus required by Section&nbsp;10(a)(3) of the
Securities Act;
</FONT>

<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(ii)&nbsp;To reflect in the prospectus any facts or events arising after the
effective date of this Registration Statement (or the most recent
post-effective amendment thereof) which, individually or in the aggregate,
represent a fundamental change in the information set forth in this
Registration Statement; and
</FONT>

<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(iii)&nbsp;To include any material information with respect to the plan of
distribution not previously disclosed in this Registration Statement or any
material change to such information in this Registration Statement;
</FONT>

<P><FONT size="2">provided, however, that paragraphs (1)(i) and (1)(ii) above do not apply if the
information required to be included in a post-effective amendment by those
paragraphs is contained in periodic reports filed by the Registrant pursuant to
Section&nbsp;13 or Section&nbsp;15(d) of the Exchange Act that are incorporated by
reference in this Registration Statement.
</FONT>
<P align="center"><font size="2">II-2</font>
<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left"><A HREF="#toc">Table of Contents</A></H5><P>
<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2)&nbsp; That, for the purpose of determining any liability under the
Securities Act, each such post-effective amendment shall be deemed to be a new
registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.
</FONT>
<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3)&nbsp; To remove from registration by means of a post-effective amendment any
of the securities being registered which remain unsold at the termination of
the offering.
</FONT>
<P><FONT size="2">B.&nbsp;The undersigned Registrant hereby undertakes that, for purposes of
determining any liability under the Securities Act, each filing of the
registrant&#146;s annual report pursuant to Section&nbsp;13(a) or 15(d) of the Exchange
Act (and, where applicable, each filing of an employee benefits plan&#146;s annual
report pursuant to Section&nbsp;15(d) of the Exchange Act) that is incorporated by
reference in this Registration Statement shall be deemed to be a new
registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.
</FONT>
<P><FONT size="2">C.&nbsp;Insofar as indemnification for liabilities arising under the Securities Act
may be permitted to directors, officers and controlling persons of the
Registrant pursuant to the foregoing provisions, or otherwise, the Registrant
has been advised that in the opinion of the Commission such indemnification is
against public policy as expressed in the Securities Act and is, therefore,
unenforceable. In the event that a claim for indemnification against such
liabilities (other than the payment by the Registrant of expenses incurred or
paid by a director, officer or controlling person of the Registrant in the
successful defense of any action, suit or proceeding) is asserted by such
director, officer or controlling person in connection with the securities being
registered, the Registrant will, unless in the opinion of its counsel the
matter has been settled by controlling precedent, submit to a court of
appropriate jurisdiction the question whether such indemnification by it is
against public policy as expressed in the Securities Act and will be governed
by the final adjudication of such issue.
</FONT>
<P align="center"><font size="2">II-3</font>
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<H5 align="left"><A HREF="#toc">Table of Contents</A></H5><P>
<!-- link1 "SIGNATURES" -->
<DIV align="left"><A NAME="008"></A></DIV>
<P align="center"><FONT size="2"><B>SIGNATURES</B></FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act of 1933, the Registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form&nbsp;S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of Seattle, State of Washington, on the 9th day of
October, 2001.
</FONT>
<CENTER>
  <TABLE cellspacing="0" border="0" cellpadding="0" width="100%">
    <TR valign="bottom">
      <TD width="50%">&nbsp;</TD>
      <TD width="5%">&nbsp;</TD>
      <TD width="45%">&nbsp;</TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">&nbsp;</TD>
      <TD colspan="2"><FONT size="2">NEORX CORPORATION</FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
    </TR>
    <TR valign="bottom">
      <TD>&nbsp;</TD>
      <TD><font size="2">By:</font></TD>
      <TD align="left"><font size="2">/S/ DOUG B. GIVEN</font></TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="left" valign="top"><FONT size="2">
        <hr size="1" noshade>
        Doug B. Given, M.D., Ph.D. <br>
        Chief Executive Officer and President</FONT></TD>
    </TR>
  </TABLE>
</CENTER>
<P align="center"><FONT size="2"><B>POWER OF ATTORNEY</B></FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Each person whose individual signature appears below hereby authorizes
Doug B. Given, M.D., Ph.D. and Richard L. Anderson, or either of them, as
attorneys-in-fact with full power of substitution, to execute in the name and
on the behalf of each person, individually and in each capacity stated below,
and to file, any and all amendments to this Registration Statement, including
any and all post-effective amendments.
</FONT>
<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed by the following persons in the
capacities indicated below on the 9th day of October, 2001.
</FONT>
<CENTER>
  <TABLE cellspacing="0" border="0" cellpadding="0" width="95%">
    <TR valign="bottom">
      <TD width="34%">&nbsp;</TD>
      <TD width="5%">&nbsp;</TD>
      <TD width="61%">&nbsp;</TD>
    </TR>
    <TR valign="bottom">
      <TD nowrap align="center"><FONT size="1"><B>Signature</B></FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD nowrap align="center"><FONT size="1"><B>Title</B></FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD nowrap align="center">
        <HR size="1" noshade>
      </TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD nowrap align="center">
        <HR size="1" noshade>
      </TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top"><FONT size="2">&nbsp;&nbsp;&nbsp;/S/ DOUG B. GIVEN
        <HR size="1" noshade>
        &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Doug B. Given, M.D., Ph.D.</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="left" valign="top"><FONT size="2"> Chief Executive Officer, President
        and Director<br>
        (Principal Executive Officer)</FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top"><FONT size="2">&nbsp;&nbsp;&nbsp;/S/ RICHARD L. ANDERSON
        <HR size="1" noshade>
        &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Richard L. Anderson</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="left" valign="top"><FONT size="2"> Chief Financial Officer and
        Senior Vice President<br>
        (Principal Financial and Accounting Officer)</FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top"><FONT size="2">&nbsp;&nbsp;&nbsp;/S/ FREDERICK B. CRAVES
        <HR size="1" noshade>
        &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Frederick B. Craves, Ph.D</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="left" valign="top"><FONT size="2"> Chairman of the Board of Directors</FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top"><FONT size="2">&nbsp;&nbsp;&nbsp;/S/ JACK L. BOWMAN
        <HR size="1" noshade>
        &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Jack L. Bowman</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="left" valign="top"><FONT size="2"> Director</FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top"><FONT size="2">&nbsp;&nbsp;&nbsp;/S/ E. ROLLAND DICKSON
        <HR size="1" noshade>
        &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;E. Rolland Dickson, M.D.</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="left" valign="top"><FONT size="2"> Director</FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top"><FONT size="2">&nbsp;&nbsp;&nbsp;/S/ CARL S. GOLDFISCHER
        <HR size="1" noshade>
        &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Carl S. Goldfischer, M.D.</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="left" valign="top"><FONT size="2"> Director</FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD align="left" valign="top">&nbsp;</TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top"><FONT size="2">&nbsp;&nbsp;&nbsp;/S/ ALAN A. STEIGROD
        <HR size="1" noshade>
        &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Alan A. Steigrod</FONT></TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="left" valign="top"><FONT size="2"> Director</FONT></TD>
    </TR>
  </TABLE>
  <br>
</CENTER>
<P align="center"><font size="2">II-4</font>
<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left"><A HREF="#toc">Table of Contents</A></H5><P>
<!-- link1 "INDEX TO EXHIBITS" -->
<DIV align="left"><A NAME="009"></A></DIV>
<P align="center"><FONT size="2"><B>INDEX TO EXHIBITS</B></FONT>

<CENTER>
  <TABLE cellspacing="0" border="0" cellpadding="0" width="90%">
    <TR valign="bottom">
      <TD width="8%">&nbsp;</TD>
      <TD width="5%">&nbsp;</TD>
      <TD width="87%">&nbsp;</TD>
    </TR>
    <TR valign="bottom">
      <TD nowrap align="center"><FONT size="1"><B>Exhibit No.</B></FONT></TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD nowrap align="center"><FONT size="1"><B>Description</B></FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD nowrap align="center">
        <HR size="1" noshade>
      </TD>
      <TD><FONT size="1">&nbsp;</FONT></TD>
      <TD nowrap align="center">
        <HR size="1" noshade>
      </TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">
        <div align="center"><FONT size="2">5.1</FONT></div>
      </TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="left" valign="top"><FONT size="2"> Opinion of Perkins Coie LLP
        regarding legality of the Common Stock being registered</FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">
        <div align="center"><FONT size="2">23.1</FONT></div>
      </TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="left" valign="top"><FONT size="2"> Consent of Independent Certified
        Public Accountants</FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">
        <div align="center"><FONT size="2">23.2</FONT></div>
      </TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="left" valign="top"><FONT size="2"> Consent of Perkins Coie LLP
        (included in opinion filed as Exhibit&nbsp;5.1)</FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">
        <div align="center"><FONT size="2">24.1</FONT></div>
      </TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="left" valign="top"><FONT size="2"> Power of Attorney (see signature
        page)</FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">
        <div align="center"><FONT size="2">99.1</FONT></div>
      </TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="left" valign="top"><FONT size="2"> NeoRx Corporation Restated
        1994 Stock Option Plan</FONT></TD>
    </TR>
    <TR valign="bottom">
      <TD valign="top">
        <div align="center"><FONT size="2">99.2</FONT></div>
      </TD>
      <TD><FONT size="2">&nbsp;</FONT></TD>
      <TD align="left" valign="top"><FONT size="2"> Stock Option Agreement dated
        July&nbsp;30, 2001</FONT></TD>
    </TR>
  </TABLE>
  <br>
  <br>
</CENTER>

<P align="center">&nbsp;
</BODY>
</HTML>
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{"company-data": {"conformed-name": "NEORX CORP", "cik": "0000755806", "assigned-sic": "2835", "irs-number": "911261311", "state-of-incorporation": "WA", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-71368", "film-number": "1756518"}, "business-address": {"street1": "410 W HARRISON ST", "city": "SEATTLE", "state": "WA", "zip": "98119", "phone": "206-286-25"}, "mail-address": {"street1": "410 W. HARRISON", "street2": "410 W. HARRISON", "city": "SEATTLE", "state": "WA", "zip": "98119"}}
Neorx Corp. Form S-8
Table of Contents
As filed with the Securities and Exchange Commission on October 10, 2001
Registration No. 333-
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-8
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
NEORX CORPORATION
(Exact name of registrant as specified in its charter)
Washington
(State of other jurisdiction of incorporation or organization)
91-1261311
(I.R.S. Employer Identification No.)
410 West Harrison Street
Seattle, Washington 98119
(Address of principal executive offices, including zip code)
NEORX CORPORATION RESTATED 1994 STOCK OPTION PLAN
STOCK OPTION AGREEMENT DATED JULY 30, 2001
(Full title of the plans)
RICHARD L. ANDERSON
Chief Financial Officer and Senior Vice President
NeoRx Corporation
410 West Harrison Street
Seattle, Washington 98119
(206) 286-2518
(Name, address and telephone number, including area code, of
  agent for service)
Copy to:
JAMES R. LISBAKKEN
Perkins Coie LLP
1201 Third Avenue, Suite 4800
Seattle, Washington 98101-3099
(206) 583-8888
CALCULATION OF REGISTRATION FEE
Proposed Maximum
Proposed Maximum
Amount to Be
Offering Price Per
Aggregate Offering
Amount of
Title of Securities
        to be Registered
Registered (1)
Share
Price
Registration Fee
Common
          Stock, par value $0.02 per share, under the:
Restated
          1994 Stock Option Plan
1,300,000
$
3.22
(2)
$
4,186,000
$
1,046.50
(2)
Stock
          Option Agreement dated July 30, 2001
150,000
$
3.35
(3)
$
502,500
$
125.63
(3)
TOTAL
1,450,000
$
4,688,500
$
1,172.13
(1)
Together with an indeterminate number of additional shares which may be
necessary to adjust the number of shares reserved for issuance pursuant
to such employee benefit plans as the result of any future stock split,
stock dividend or similar adjustment of the Registrant's outstanding
Common Stock.
(2)
Estimated solely for the purpose of calculating the registration fee
pursuant to Rule 457(c) under the Securities Act of 1933, as amended.
The calculation of the registration fee is based upon a per share price
of $3.22, which was the average of the high ($3.38) and low ($3.06)
sales prices of the Registrant's common stock on October 9, 2001, as
reported by the NASDAQ National Market.
(3)
Computed pursuant to Rule 457(h) under the Securities Act of 1933, as
amended, based on the exercise price of the stock option issued pursuant
to the stock option agreement.
TABLE OF CONTENTS
PART II INFORMATION REQUIRED IN REGISTRATION STATEMENT
Item 3. INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE
Item 4. DESCRIPTION OF SECURITIES
Item 5. INTERESTS OF NAMED EXPERTS AND COUNSEL
Item 6. INDEMNIFICATION OF DIRECTORS AND OFFICERS
Item 7. EXEMPTION FROM REGISTRATION CLAIMED
Item 8. EXHIBITS
Item 9. UNDERTAKINGS
SIGNATURES
INDEX TO EXHIBITS
EXHIBIT 5.1
EXHIBIT 23.1
EXHIBIT 99.1
EXHIBIT 99.2
Table of Contents
PART II
INFORMATION REQUIRED IN REGISTRATION STATEMENT
Item 3. INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE
The following documents filed by the Registrant with the Securities and
Exchange Commission (the "Commission") are hereby incorporated by reference in
this Registration Statement:
(a)  The Registrant's Annual Report on Form 10-K for the year ended
December 31, 2000, filed on March 30, 2001, which contains audited financial
statements for the most recent fiscal year for which such statements have been
filed;
(b)  The Registrant's Quarterly Reports on Form 10-Q for the fiscal
quarters ended March 31, 2001 and June 30, 2001 filed on May 14, 2001 and
August 6, 2001, respectively;
(c)  The description of the Registrant's common stock contained in the
Registration Statement on Form 8-A, filed on March 21, 1988, under Section
12(g) of the Securities Exchange Act of 1934, as amended (the "Exchange Act"),
including any amendments or reports filed for the purpose of updating such
description; and
(d)  All other reports filed pursuant to Section 13(a) or 15(d) of the
Exchange Act since the end of the fiscal year covered by the Annual Report on
Form 10-K referred to in (a) above.
All documents filed by the Registrant pursuant to Sections 13(a), 13(c),
14 and 15(d) of the Exchange Act after the date hereof, and prior to the filing
of a post-effective amendment which indicates that the securities offered
hereby have been sold or which deregisters the securities covered hereby then
remaining unsold, shall also be deemed to be incorporated by reference into
this Registration Statement and to be a part hereof commencing on the
respective dates on which such documents are filed.
Item 4. DESCRIPTION OF SECURITIES
Not applicable.
Item 5. INTERESTS OF NAMED EXPERTS AND COUNSEL
Not applicable.
Item 6. INDEMNIFICATION OF DIRECTORS AND OFFICERS
Sections 23B.08.500 through 23B.08.600 of the Washington Business
Corporation Act authorize a court to award, or a corporation's board of
directors to grant, indemnification to directors and officers on terms
sufficiently broad to permit indemnification under certain circumstances for
liabilities arising under the Securities Act of 1933, as amended (the
"Securities Act"). Article XIII of the Registrant's Restated Articles of
Incorporation and Section 12 of the Registrant's Bylaws provide for
indemnification of the Registrant's directors, officers, employees and agents
to the maximum extent permitted by Washington law and provide that the
directors and officers of the Registrant may also be indemnified against
liability they may incur for serving in those capacities pursuant to a
liability insurance policy maintained by the Registrant for such purpose.
II-1
Table of Contents
Section 23B.08.320 of the Washington Business Corporation Act authorizes a
corporation to limit a director's liability to the corporation or its
shareholders for monetary damages for acts or omissions as a director, except
in certain circumstances involving intentional misconduct, knowing violations
of law or illegal corporate loans or distributions, or any transactions from
which the director personally receives a benefit in money, property or services
to which the director is not legally entitled. Article XII of the Registrant's
Restated Articles of Incorporation contains provisions implementing, to the
fullest extent permitted by Washington law, such limitations on a director's
liability to the Registrant and its shareholders.
Item 7. EXEMPTION FROM REGISTRATION CLAIMED
Not applicable.
Item 8. EXHIBITS
Exhibit No.
Description
5.1
Opinion of Perkins Coie LLP
        regarding legality of the Common Stock being registered
23.1
Consent of Independent Certified
        Public Accountants
23.2
Consent of Perkins Coie LLP
        (included in opinion filed as Exhibit 5.1)
24.1
Power of Attorney (see signature
        page)
99.1
NeoRx Corporation Restated
        1994 Stock Option Plan
99.2
Stock Option Agreement dated
        July 30, 2001
Item 9. UNDERTAKINGS
A. The undersigned Registrant hereby undertakes:
(1)  To file, during any period in which offers or sales are being made, a
post-effective amendment to this Registration Statement:
(i) To include any prospectus required by Section 10(a)(3) of the
Securities Act;
(ii) To reflect in the prospectus any facts or events arising after the
effective date of this Registration Statement (or the most recent
post-effective amendment thereof) which, individually or in the aggregate,
represent a fundamental change in the information set forth in this
Registration Statement; and
(iii) To include any material information with respect to the plan of
distribution not previously disclosed in this Registration Statement or any
material change to such information in this Registration Statement;
provided, however, that paragraphs (1)(i) and (1)(ii) above do not apply if the
information required to be included in a post-effective amendment by those
paragraphs is contained in periodic reports filed by the Registrant pursuant to
Section 13 or Section 15(d) of the Exchange Act that are incorporated by
reference in this Registration Statement.
II-2
Table of Contents
(2)  That, for the purpose of determining any liability under the
Securities Act, each such post-effective amendment shall be deemed to be a new
registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.
(3)  To remove from registration by means of a post-effective amendment any
of the securities being registered which remain unsold at the termination of
the offering.
B. The undersigned Registrant hereby undertakes that, for purposes of
determining any liability under the Securities Act, each filing of the
registrant's annual report pursuant to Section 13(a) or 15(d) of the Exchange
Act (and, where applicable, each filing of an employee benefits plan's annual
report pursuant to Section 15(d) of the Exchange Act) that is incorporated by
reference in this Registration Statement shall be deemed to be a new
registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.
C. Insofar as indemnification for liabilities arising under the Securities Act
may be permitted to directors, officers and controlling persons of the
Registrant pursuant to the foregoing provisions, or otherwise, the Registrant
has been advised that in the opinion of the Commission such indemnification is
against public policy as expressed in the Securities Act and is, therefore,
unenforceable. In the event that a claim for indemnification against such
liabilities (other than the payment by the Registrant of expenses incurred or
paid by a director, officer or controlling person of the Registrant in the
successful defense of any action, suit or proceeding) is asserted by such
director, officer or controlling person in connection with the securities being
registered, the Registrant will, unless in the opinion of its counsel the
matter has been settled by controlling precedent, submit to a court of
appropriate jurisdiction the question whether such indemnification by it is
against public policy as expressed in the Securities Act and will be governed
by the final adjudication of such issue.
II-3
Table of Contents
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, the Registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of Seattle, State of Washington, on the 9th day of
October, 2001.
NEORX CORPORATION
By:
/S/ DOUG B. GIVEN
Doug B. Given, M.D., Ph.D.
Chief Executive Officer and President
POWER OF ATTORNEY
Each person whose individual signature appears below hereby authorizes
Doug B. Given, M.D., Ph.D. and Richard L. Anderson, or either of them, as
attorneys-in-fact with full power of substitution, to execute in the name and
on the behalf of each person, individually and in each capacity stated below,
and to file, any and all amendments to this Registration Statement, including
any and all post-effective amendments.
Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed by the following persons in the
capacities indicated below on the 9th day of October, 2001.
Signature
Title
/S/ DOUG B. GIVEN
Doug B. Given, M.D., Ph.D.
Chief Executive Officer, President
        and Director
(Principal Executive Officer)
/S/ RICHARD L. ANDERSON
Richard L. Anderson
Chief Financial Officer and
        Senior Vice President
(Principal Financial and Accounting Officer)
/S/ FREDERICK B. CRAVES
Frederick B. Craves, Ph.D
Chairman of the Board of Directors
/S/ JACK L. BOWMAN
Jack L. Bowman
Director
/S/ E. ROLLAND DICKSON
E. Rolland Dickson, M.D.
Director
/S/ CARL S. GOLDFISCHER
Carl S. Goldfischer, M.D.
Director
/S/ ALAN A. STEIGROD
Alan A. Steigrod
Director
II-4
Table of Contents
INDEX TO EXHIBITS
Exhibit No.
Description
5.1
Opinion of Perkins Coie LLP
        regarding legality of the Common Stock being registered
23.1
Consent of Independent Certified
        Public Accountants
23.2
Consent of Perkins Coie LLP
        (included in opinion filed as Exhibit 5.1)
24.1
Power of Attorney (see signature
        page)
99.1
NeoRx Corporation Restated
        1994 Stock Option Plan
99.2
Stock Option Agreement dated
        July 30, 2001