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 <p align="center" style="margin:0pt 0pt .0001pt;text-align:center;"><a name="scotch"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;">As filed with the Securities and Exchange Commission on June&nbsp;14, 2005</font></b></a></p> <div style="border:none;border-bottom:double windowtext 6.0pt;padding:0pt 0pt 1.0pt 0pt;"> <p align="right" style="border:none;margin:0pt 0pt 12.0pt;padding:0pt;text-align:right;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;">Registration No.&nbsp;333-_______</font></b></p> </div>

<p style="font-weight:bold;margin:0pt 0pt .0001pt;page-break-after:avoid;text-align:center;"><b><font size="5" face="Times New Roman" style="font-size:18.0pt;">SECURITIES AND EXCHANGE COMMISSION</font></b></p>

<p style="font-weight:bold;margin:0pt 0pt 10.0pt;page-break-after:avoid;text-align:center;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;">WASHINGTON,
D.C. 20549</font></b></p>

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<p style="font-size:18.0pt;font-weight:bold;margin:0pt 0pt .0001pt;page-break-after:avoid;text-align:center;">FORM&nbsp;S-8</p>

<p style="font-weight:bold;margin:0pt 0pt 10.0pt;page-break-after:avoid;text-align:center;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;">REGISTRATION
STATEMENT UNDER<br>
THE SECURITIES ACT OF 1933</font></b></p>

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<p style="font-size:18.0pt;font-weight:bold;margin:0pt 0pt .0001pt;page-break-after:avoid;text-align:center;">MEDIMMUNE, INC.</p>

<p style="font-weight:bold;margin:0pt 0pt 14.0pt;page-break-after:avoid;text-align:center;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:normal;">(Exact name of registrant as
specified in its charter)</font></b></p>

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 <tr>
  <td width="160" valign="top" style="padding:0pt .7pt 0pt 0pt;width:120.0pt;">
  <p align="center" style="font-size:10.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font style="font-weight:bold;">DELAWARE<br>
  </font></b>(State or other jurisdiction<br>
  of incorporation or<br>
  organization)</p>
  </td>
  <td width="8" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:6.0pt;">
  <p align="center" style="margin:0pt 0pt .0001pt;text-align:center;"><b><font size="2" face="Times New Roman" style="font-size:1.0pt;font-weight:bold;">&nbsp;</font></b></p>
  </td>
  <td width="293" valign="top" style="padding:0pt .7pt 0pt 0pt;width:220.0pt;">
  <p align="center" style="font-size:10.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;">One
  MedImmune Way<br>
  Gaithersburg, Maryland 20878 <br>
  </font></b>(Address of Principal Executive Offices) (Zip Code)</p>
  </td>
  <td width="8" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:6.0pt;">
  <p align="center" style="margin:0pt 0pt .0001pt;text-align:center;"><b><font size="2" face="Times New Roman" style="font-size:1.0pt;font-weight:bold;">&nbsp;</font></b></p>
  </td>
  <td width="160" valign="top" style="padding:0pt .7pt 0pt 0pt;width:120.0pt;">
  <p align="center" style="font-size:10.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;">55-1555759<br>
  </font></b>(I.R.S. Employer<br>
  Identification No.)</p>
  </td>
 </tr>
</table>

</div>

<p style="line-height:1.0pt;margin:0pt 0pt 13.0pt;"><font size="1" face="Times New Roman">&nbsp;</font></p>

<p style="line-height:9.0pt;margin:0pt 0pt 8.0pt;text-align:center;"></p>

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<p style="font-size:10.0pt;font-weight:bold;margin:0pt 0pt .0001pt;page-break-after:avoid;text-align:center;">2004
Stock Incentive Plan</p>

<p style="margin:0pt 0pt 11.0pt;page-break-after:avoid;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">(Full Title of the Plan)</font></p>

<p style="line-height:9.0pt;margin:0pt 0pt 10.0pt;text-align:center;"></p>

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<p style="font-size:10.0pt;font-weight:bold;margin:0pt 0pt .0001pt;page-break-after:avoid;text-align:center;">David
M. Mott<br>
Chief Executive Officer, President and Vice Chairman<br>
MedImmune,&nbsp;Inc.<br>
One MedImmune Way<br>
Gaithersburg, Maryland 20878</p>

<p style="margin:0pt 0pt 10.0pt;page-break-after:avoid;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">(Name and address of agent
for service)</font></p>

<p style="line-height:9.0pt;margin:0pt 0pt 10.0pt;text-align:center;"></p>

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</font></div>

<p style="font-size:10.0pt;font-weight:bold;margin:0pt 0pt 11.0pt;page-break-after:avoid;text-align:center;">Telephone number, including
area code, of agent for service: <br>
(301) 398-0000</p>

<p style="font-weight:bold;margin:0pt 0pt 12.0pt;page-break-after:avoid;text-align:center;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;">CALCULATION
OF REGISTRATION FEE</font></b></p>

<table border="0" cellspacing="0" cellpadding="0" style="border-collapse:collapse;">
 <tr>
  <td width="231" valign="bottom" style="border:none;border-bottom:solid windowtext 1.0pt;padding:0pt .7pt 0pt 0pt;width:173.3pt;">
  <p style="font-size:8.0pt;font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;page-break-after:avoid;text-align:center;">Title&nbsp;of&nbsp;Each&nbsp;Class&nbsp;of<br>
  Securities<br>
  To&nbsp;Be&nbsp;Registered</p>
  </td>
  <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:12.2pt;">
  <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;page-break-after:avoid;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
  </td>
  <td width="64" colspan="3" valign="bottom" style="border:none;border-bottom:solid windowtext 1.0pt;padding:0pt .7pt 0pt 0pt;width:48.3pt;">
  <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;page-break-after:avoid;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:8.0pt;">Amount<br>
  To&nbsp;Be<br>
  Registered(1)</font></b></p>
  </td>
  <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:12.25pt;">
  <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;page-break-after:avoid;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
  </td>
  <td width="95" colspan="4" valign="bottom" style="border:none;border-bottom:solid windowtext 1.0pt;padding:0pt .7pt 0pt 0pt;width:71.25pt;">
  <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;page-break-after:avoid;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:8.0pt;">Proposed&nbsp;Maximum<br>
  Offering&nbsp;Price<br>
  Per&nbsp;Share(2)</font></b></p>
  </td>
  <td width="15" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:11.55pt;">
  <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;page-break-after:avoid;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
  </td>
  <td width="95" colspan="4" valign="bottom" style="border:none;border-bottom:solid windowtext 1.0pt;padding:0pt .7pt 0pt 0pt;width:71.3pt;">
  <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;page-break-after:avoid;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:8.0pt;">Proposed&nbsp;Maximum<br>
  Aggregate&nbsp;Offering<br>
  Price(2)</font></b></p>
  </td>
  <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:12.25pt;">
  <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;page-break-after:avoid;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
  </td>
  <td width="91" colspan="4" valign="bottom" style="border:none;border-bottom:solid windowtext 1.0pt;padding:0pt .7pt 0pt 0pt;width:68.4pt;">
  <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;page-break-after:avoid;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:8.0pt;">Amount&nbsp;of<br>
  Registration&nbsp;Fee(3)</font></b></p>
  </td>
  <td width="2" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:1.75pt;">
  <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
  </td>
 </tr>
 <tr>
  <td width="231" valign="top" style="border:none;padding:0pt .7pt 0pt 0pt;width:173.3pt;">
  <p style="margin:0pt 0pt .0001pt 10.0pt;page-break-after:avoid;text-indent:-10.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Common Stock,
  $.01 par value per share<font style="letter-spacing:2.25pt;">&nbsp;</font></font></p> </td>
  <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:12.2pt;">
  <p style="margin:0pt 0pt .0001pt;page-break-after:avoid;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="5" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:3.4pt;">
  <p style="margin:0pt 0pt .0001pt;text-align:right;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="55" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:41.5pt;">
  <p style="margin:0pt 0pt .0001pt;text-align:right;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">8,000,000</font></p>
  </td>
  <td width="5" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:3.4pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:12.25pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="28" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:21.1pt;">
  <p style="margin:0pt 0pt .0001pt;text-align:right;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="7" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:5.0pt;">
  <p align="left" style="margin:0pt 0pt .0001pt;text-align:left;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">$</font></p>
  </td>
  <td width="32" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:24.0pt;">
  <p style="margin:0pt 0pt .0001pt;text-align:right;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">26.08</font></p>
  </td>
  <td width="28" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:21.15pt;">
  <p style="margin:0pt 0pt .0001pt;text-align:right;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="15" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:11.55pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="10" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:7.4pt;">
  <p style="margin:0pt 0pt .0001pt;text-align:right;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="7" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:5.0pt;">
  <p align="left" style="margin:0pt 0pt .0001pt;text-align:left;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">$</font></p>
  </td>
  <td width="69" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:51.5pt;">
  <p style="margin:0pt 0pt .0001pt;text-align:right;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">208,640,000</font></p>
  </td>
  <td width="10" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:7.4pt;">
  <p style="margin:0pt 0pt .0001pt;text-align:right;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:12.25pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="23" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:17.2pt;">
  <p style="margin:0pt 0pt .0001pt;text-align:right;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="7" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:5.0pt;">
  <p align="left" style="margin:0pt 0pt .0001pt;text-align:left;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">$</font></p>
  </td>
  <td width="39" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:29.0pt;">
  <p style="margin:0pt 0pt .0001pt;text-align:right;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">24,557</font></p>
  </td>
  <td width="23" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:17.2pt;">
  <p style="margin:0pt 0pt .0001pt;text-align:right;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="2" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:1.75pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
 </tr>
 <tr height="0">
  <td width="231" style="border:none;"></td>
  <td width="16" style="border:none;"></td>
  <td width="5" style="border:none;"></td>
  <td width="55" style="border:none;"></td>
  <td width="5" style="border:none;"></td>
  <td width="16" style="border:none;"></td>
  <td width="28" style="border:none;"></td>
  <td width="7" style="border:none;"></td>
  <td width="32" style="border:none;"></td>
  <td width="28" style="border:none;"></td>
  <td width="15" style="border:none;"></td>
  <td width="10" style="border:none;"></td>
  <td width="7" style="border:none;"></td>
  <td width="69" style="border:none;"></td>
  <td width="10" style="border:none;"></td>
  <td width="16" style="border:none;"></td>
  <td width="23" style="border:none;"></td>
  <td width="7" style="border:none;"></td>
  <td width="39" style="border:none;"></td>
  <td width="23" style="border:none;"></td>
  <td width="2" style="border:none;"></td>
 </tr>
</table>

<p style="line-height:1.0pt;margin:0pt 0pt 11.0pt;page-break-after:avoid;"><font size="1" face="Times New Roman">&nbsp;</font></p>

<p style="font-size:10.0pt;margin:0pt 0pt 6.0pt 20.0pt;text-indent:-20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">(1)</font><font size="1" face="Times New Roman" style="font-size:3.0pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font>Plus such additional
shares as may be issued by reason of stock splits, stock dividends or similar
transactions.</p>

<p style="font-size:10.0pt;margin:0pt 0pt 6.0pt 20.0pt;text-indent:-20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">(2)</font><font size="1" face="Times New Roman" style="font-size:3.0pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font>Pursuant to Rules&nbsp;457(h)&nbsp;and
457(c), these prices are estimated solely for the purpose of calculating the
registration fee and are based upon the average of the high and low sales
prices of the Registrant&#146;s common stock on the Nasdaq National Market on June&nbsp;13,
2005.</p>

<p style="font-size:10.0pt;margin:0pt 0pt 6.0pt 20.0pt;text-indent:-20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">(3)</font><font size="1" face="Times New Roman" style="font-size:3.0pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font>Pursuant to Rule&nbsp;457(p),
the aggregate amount of the registration fee is being offset by $6,139,
representing the dollar amount of the registration fee previously paid by the
Registrant in respect of 2,000,000 unissued shares previously registered on a Form&nbsp;S-8
and with respect to which the offering is complete. Accordingly, the adjusted
registration fee for this Form&nbsp;S-8 is $18,418.</p>


 <div style="border:none;border-bottom:double windowtext 6.0pt;padding:0pt 0pt 0pt 0pt;"> <p style="border:none;margin:0pt 0pt .0001pt;padding:0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">&nbsp;</font></p> </div>
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<p style="color:windowtext;font-weight:bold;margin:0pt 0pt 6.0pt;page-break-after:avoid;text-align:center;"><a name="ExplanatoryStatement_021034"></a><b><font size="2" face="Times New Roman" style="font-size:10.0pt;">EXPLANATORY STATEMENT</font></b></p>

<p style="color:windowtext;margin:0pt 0pt 12.0pt;text-indent:20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">This Form&nbsp;S-8
Registration Statement is being filed with the Securities and Exchange
Commission (the &#147;Commission&#148;) by MedImmune,&nbsp;Inc., a Delaware corporation
(the &#147;Company&#148;), in order to register 8,000,000 shares of the Company&#146;s common
stock, par value $.01 per share (the &#147;Common Stock&#148;), issuable upon exercise of
stock options (including &#147;incentive stock options&#148;), stock appreciation rights,
restricted stock, stock units and stock awards granted or to be granted under
the Company&#146;s 2004 Stock Incentive Plan (the &#147;Plan&#148;). On August&nbsp;5, 2004,
the Company filed with the Commission a Registration Statement on Form&nbsp;S-8
(Registration No.&nbsp;333-117963) registering up to 13,000,000 shares of
Common Stock issuable under the Plan (the &#147;Initial Registration Statement&#148;).
With the addition of 8,000,000 shares pursuant to this Registration Statement,
the total number of shares now registered for issuance pursuant to the Plan is
21,000,000. Pursuant to General Instruction E of Form&nbsp;S-8, the Company
hereby incorporates by reference in this Registration Statement all contents of
the Prior Registration Statements, including the exhibits thereto.</font></p>

<p style="color:windowtext;font-weight:bold;margin:0pt 0pt 6.0pt;page-break-after:avoid;text-align:center;"><a name="Parti_021036"></a><b><font size="2" face="Times New Roman" style="font-size:10.0pt;">PART&nbsp;I</font></b></p>

<p style="color:windowtext;font-weight:bold;margin:0pt 0pt 6.0pt;page-break-after:avoid;text-align:center;"><a name="InformationRequiredInTheSection10_021036"></a><b><font size="2" face="Times New Roman" style="font-size:10.0pt;">INFORMATION REQUIRED IN THE SECTION&nbsp;10(a)&nbsp;PROSPECTUS</font></b></p>

<p style="color:windowtext;margin:0pt 0pt 12.0pt;text-indent:20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">The information specified
in Item 1 and Item 2 of Part&nbsp;I of this Registration Statement on Form&nbsp;S-8
(the &#147;Registration Statement&#148;) is omitted from this filing in accordance with
the provisions of Rule&nbsp;428 under the Securities Act of 1933, as amended.
The documents containing the information specified in Part&nbsp;I will be
delivered to the participants in the plan covered by this Registration
Statement as required by Rule&nbsp;428.</font></p>

<p style="color:windowtext;font-weight:bold;margin:0pt 0pt 6.0pt;page-break-after:avoid;text-align:center;"><a name="Partii_021037"></a><b><font size="2" face="Times New Roman" style="font-size:10.0pt;">PART&nbsp;II</font></b></p>

<p style="color:windowtext;font-weight:bold;margin:0pt 0pt 6.0pt;page-break-after:avoid;text-align:center;"><a name="InformationRequiredInTheRegistrat_021038"></a><b><font size="2" face="Times New Roman" style="font-size:10.0pt;">INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</font></b></p>

<p style="color:windowtext;font-weight:bold;margin:0pt 0pt 6.0pt 10.0pt;page-break-after:avoid;text-indent:-10.0pt;"><a name="Item3_IncorporationOfDocumentsByR_021039"></a><b><font size="2" face="Times New Roman" style="font-size:10.0pt;">Item
3.&#160;&#160; Incorporation of Documents by
Reference.</font></b></p>

<p style="color:windowtext;margin:0pt 0pt 6.0pt;page-break-after:avoid;text-indent:20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">The following
documents filed with the Commission are hereby incorporated by reference:</font></p>

<p style="color:windowtext;font-family:Times New Roman;font-size:10.0pt;margin:0pt 0pt 6.0pt 40.0pt;text-indent:-20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">a)</font><font size="1" face="Times New Roman" style="font-size:3.0pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font>The Registrant&#146;s
Annual Report on Form&nbsp;10-K for the fiscal year ended December&nbsp;31,
2004, as amended;</p>

<p style="color:windowtext;font-family:Times New Roman;font-size:10.0pt;margin:0pt 0pt 6.0pt 40.0pt;text-indent:-20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">b)</font><font size="1" face="Times New Roman" style="font-size:3.0pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font>The Registrant&#146;s
Quarterly Report on Form&nbsp;10-Q for the quarter ended March&nbsp;31, 2005;</p>

<p style="color:windowtext;font-family:Times New Roman;font-size:10.0pt;margin:0pt 0pt 6.0pt 40.0pt;text-indent:-20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">c)</font><font size="1" face="Times New Roman" style="font-size:3.0pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font>The Registrant&#146;s
Current Reports on Form&nbsp;8-K filed on February&nbsp;3, 2005, February&nbsp;23,
2005, March&nbsp;3, 2005, April&nbsp;6, 2005, April&nbsp;15, 2005, April&nbsp;21,
2005 and May&nbsp;24, 2005; and</p>

<p style="color:windowtext;font-family:Times New Roman;font-size:10.0pt;margin:0pt 0pt 6.0pt 40.0pt;text-indent:-20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">d)</font><font size="1" face="Times New Roman" style="font-size:3.0pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font>The description of
the Registrant&#146;s Common Stock set forth under the caption &#147;Description of
Capital Stock&#148; in the Registrant&#146;s registration statement on Form&nbsp;8-A
dated April&nbsp;4, 1991 pursuant to Section&nbsp;12 of the Securities Exchange
Act of 1934, as amended (the &#147;Exchange Act&#148;) including all amendments or
reports filed with the Commission for the purpose of updating such description.</p>

<p style="color:windowtext;margin:0pt 0pt 6.0pt;text-indent:20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">All other documents subsequently filed by the
Registrant pursuant to Sections 13(a), 13(c), 14 and 15(d)&nbsp;of the Exchange
Act prior to the filing of a post-effective amendment which indicates that all
securities offered hereunder have been sold or which deregisters all such
securities then remaining unsold shall be deemed to be incorporated by
reference in this Registration Statement and be a part hereof from the date of
filing of such documents.</font></p>

<p style="color:windowtext;margin:0pt 0pt 12.0pt;text-indent:20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Any statement contained
herein or in a document incorporated or deemed to be incorporated by reference
herein shall be deemed to be modified or superseded for purposes of this
Registration Statement to the extent that a statement contained herein or in
any other subsequently filed document which also is </font></p>


 <p style="color:windowtext;font-size:10.0pt;margin:24.0pt 0pt .0001pt;text-align:center;"><font face="Times New Roman">1</font></p> <br><hr size="3" width="100%" noshade color="#010101" align="center">

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<p style="color:windowtext;margin:0pt 0pt 12.0pt;text-indent:0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">or is
deemed to be incorporated by reference herein modifies or supersedes such
earlier statement. Any statement so modified or superseded shall not be deemed,
except as so modified or superseded, to constitute a part of this Registration
Statement.</font></p>

<p style="color:windowtext;font-weight:bold;margin:0pt 0pt 6.0pt 10.0pt;page-break-after:avoid;text-indent:-10.0pt;"><a name="Item4_DescriptionOfSecurities__021154"></a><b><font size="2" face="Times New Roman" style="font-size:10.0pt;">Item 4. &#160;&#160;Description of Securities.</font></b></p>

<p style="color:windowtext;margin:0pt 0pt 12.0pt;text-indent:20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Not applicable.</font></p>

<p style="color:windowtext;font-weight:bold;margin:0pt 0pt 6.0pt 10.0pt;page-break-after:avoid;text-indent:-10.0pt;"><a name="Item5_InterestsOfNamedExpertsAndC_021158"></a><b><font size="2" face="Times New Roman" style="font-size:10.0pt;">Item
5. &#160;&#160;Interests of Named Experts and Counsel.</font></b></p>

<p style="color:windowtext;margin:0pt 0pt 12.0pt;text-indent:20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">The validity of the common
stock issuable under the 2004 Stock Incentive Plan has been passed upon for the
Registrant by Dewey Ballantine LLP, New York, New York. A member of Dewey
Ballantine LLP participating in this matter is the beneficial owner of less
than 1% of the Registrant&#146;s common stock.</font></p>

<p style="color:windowtext;font-weight:bold;margin:0pt 0pt 6.0pt 10.0pt;page-break-after:avoid;text-indent:-10.0pt;"><a name="Item6_IndemnificationOfDirectorsA_021159"></a><b><font size="2" face="Times New Roman" style="font-size:10.0pt;">Item
6. &#160;&#160;Indemnification of Directors and Officers.</font></b></p>

<p style="color:windowtext;margin:0pt 0pt 6.0pt;text-indent:20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;letter-spacing:-.1pt;">Subsection (a)&nbsp;of Section&nbsp;145
of the General Corporation Law of the State of Delaware (the &#147;DGCL&#148;) empowers a
corporation to indemnify any person who was or is a party or who is threatened
to be made a party to any threatened, pending or completed action, suit or
proceeding, whether civil, criminal, administrative or investigative (other
than an action by or in the right of the corporation) by reason of the fact
that the person is or was a director, officer, employee or agent of the
corporation, or is or was serving at the request of the corporation as a
director, officer, employee or agent of another corporation, partnership, joint
venture, trust or other enterprise, against expenses (including attorney&#146;s
fees), judgments, fines and amounts paid in settlement actually and reasonably incurred
by the person in connection with such action, suit or proceeding if the person
acted in good faith and in a manner the person reasonably believed to be in or
not opposed to the best interests of the corporation, and, with respect to any
criminal action or proceeding, had no reasonable cause to believe the person&#146;s
conduct was unlawful.</font></p>

<p style="color:windowtext;margin:0pt 0pt 6.0pt;text-indent:20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Subsection (b)&nbsp;of Section&nbsp;145 of the DGCL
empowers a corporation to indemnify any person who was or is a party or is
threatened to be made a party to any threatened, pending or completed action or
suit by or in the right of the corporation to procure a judgment in its favor
by reason of the fact that the person acted in any of the capacities set forth
above, against expenses (including attorney&#146;s fees) actually and reasonably
incurred by the person in connection with the defense or settlement of such
action or suit if the person acted in good faith and in a manner the person
reasonably believed to be in or not opposed to the best interests of the
corporation, and except that no indemnification shall be made in respect of any
claim, issue or matter as to which such person shall have been adjudged to be
liable to the corporation unless and only to the extent that the Court of
Chancery or the court in which such action or suit was brought shall determine
upon application that, despite the adjudication of liability but in view of all
the circumstances of the case, such person is fairly and reasonably entitled to
indemnity for such expenses which the Court of Chancery or such other court
shall deem proper.</font></p>

<p style="color:windowtext;margin:0pt 0pt 6.0pt;text-indent:20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;letter-spacing:-.1pt;">Section&nbsp;145 further provides
that to the extent a present or former director or officer of a corporation has
been successful on the merits or otherwise in the defense of any action, suit
or proceeding referred to in subsections (a)&nbsp;and (b)&nbsp;of Section&nbsp;145,
or in defense of any claim, issue or matter therein, such person shall be
indemnified against expenses (including attorneys&#146; fees) actually and
reasonably incurred by such person in connection therewith; that
indemnification provided for by Section&nbsp;145 shall not be deemed exclusive
of any other rights to which the indemnified party may be entitled; the
indemnification provided for by Section&nbsp;145 shall, unless otherwise
provided when authorized or ratified, continue as to a person who has ceased to
be a director, officer, employee or agent and shall inure to the benefit of the
heirs, executors and administrators of such a person; and empowers the
corporation to purchase and maintain insurance on behalf of any person who is
or was a director, officer, employee or agent of the corporation, or is or was
serving at the request of the corporation as a director, officer, employee or
agent of another corporation, partnership, joint venture, </font></p>


 <p style="color:windowtext;font-size:10.0pt;margin:24.0pt 0pt .0001pt;text-align:center;"><font face="Times New Roman">2</font></p> <br><hr size="3" width="100%" noshade color="#010101" align="center">

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<p style="color:windowtext;margin:0pt 0pt 6.0pt;text-indent:0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;letter-spacing:-.1pt;">trust
or other enterprise against any liability asserted against such person and
incurred by such person in any such capacity, or arising out of such person&#146;s
status as such, whether or not the corporation would have the power to
indemnify such person against such liabilities under Section&nbsp;145.</font></p>

<p style="color:windowtext;margin:0pt 0pt 6.0pt;text-indent:20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">In addition, Section&nbsp;145(g)&nbsp;of the DGCL
provides, in general, that a corporation shall have the power to purchase and
maintain insurance on behalf of any person who is or was a director or officer
of the corporation against any liability asserted against the person in any
such capacity, or arising out of the person&#146;s status as such, whether or not
the corporation would have the power to indemnify the person against such
liability under the provisions of the law.</font></p>

<p style="color:windowtext;margin:0pt 0pt 6.0pt;text-indent:20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Article&nbsp;IX of the Company&#146;s By-laws provides that
the Company shall indemnify its directors and officers to the extent permitted
by Delaware law. The Company provides liability insurance for its directors and
officers which provides for coverage against loss from claims made against
directors and officers in their capacity as such, including liabilities under
Securities Act of 1933, as amended.</font></p>

<p style="color:windowtext;margin:0pt 0pt 12.0pt;text-indent:20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Section&nbsp; 102(b)(7)&nbsp;of
the DGCL provides that a certificate of incorporation may contain a provision
eliminating or limiting the personal liability of a director to the corporation
or its stockholders for monetary damages for breach of fiduciary duty as a
director, provided that such provision shall not eliminate or limit the
liability of a director (i)&nbsp;for any breach of the director&#146;s duty of
loyalty to the corporation or its stockholders, (ii)&nbsp;for acts or omissions
not in good faith or which involve intentional misconduct or a knowing
violation of law, (iii)&nbsp;under Section&nbsp;174 of the DGCL, or (iv)&nbsp;for
any transaction from which the director derived an improper personal benefit.
Article&nbsp;EIGHTH of the Company&#146;s Certificate of Incorporation limits the
liability of directors to the fullest extent permitted by Section&nbsp;102(b)(7).</font></p>

<p style="color:windowtext;font-weight:bold;margin:0pt 0pt 6.0pt 10.0pt;page-break-after:avoid;text-indent:-10.0pt;"><a name="Item7_ExemptionFromRegistrationCl_021208"></a><b><font size="2" face="Times New Roman" style="font-size:10.0pt;">Item
7. &#160;&#160;Exemption from Registration Claimed.</font></b></p>

<p style="color:windowtext;margin:0pt 0pt 12.0pt;text-indent:20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Not applicable.</font></p>

<p style="color:windowtext;font-weight:bold;margin:0pt 0pt 6.0pt 10.0pt;page-break-after:avoid;text-indent:-10.0pt;"><a name="Item8_Exhibits__021209"></a><b><font size="2" face="Times New Roman" style="font-size:10.0pt;">Item 8.&#160; &#160;Exhibits.</font></b></p>

<p style="color:windowtext;margin:0pt 0pt 12.0pt;page-break-after:avoid;text-indent:20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">The
following documents are filed as Exhibits hereto:</font></p>

<table border="0" cellspacing="0" cellpadding="0" style="border-collapse:collapse;font-family:Times New Roman;">
 <tr>
  <td width="44" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:33.25pt;">
  <p align="left" style="color:windowtext;font-size:8.0pt;font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:left;">Exhibit</p>
  </td>
  <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:11.85pt;">
  <p style="color:windowtext;font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
  </td>
  <td width="419" colspan="3" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:314.15pt;">
  <p style="color:windowtext;font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
  </td>
  <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:11.85pt;">
  <p style="color:windowtext;font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
  </td>
  <td width="114" colspan="3" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:85.6pt;">
  <p style="color:windowtext;font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:8.0pt;">Sequentially Numbered</font></b></p>
  </td>
 </tr>
 <tr>
  <td width="44" valign="bottom" style="border:none;border-bottom:solid windowtext 1.0pt;padding:0pt .7pt 0pt 0pt;width:33.25pt;">
  <p align="left" style="color:windowtext;font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:left;"><b><font size="1" face="Times New Roman" style="font-size:8.0pt;">Number</font></b></p>
  </td>
  <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:11.85pt;">
  <p style="color:windowtext;font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
  </td>
  <td width="55" valign="bottom" style="border:none;border-bottom:solid windowtext 1.0pt;padding:0pt .7pt 0pt 0pt;width:41.2pt;">
  <p align="left" style="color:windowtext;font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:left;"><b><font size="1" face="Times New Roman" style="font-size:8.0pt;">Description</font></b></p>
  </td>
  <td width="7" valign="bottom" style="border:none;border-bottom:solid windowtext 1.0pt;padding:0pt .7pt 0pt 0pt;width:4.95pt;">
  <p style="color:windowtext;font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
  </td>
  <td width="357" valign="bottom" style="border:none;border-bottom:solid windowtext 1.0pt;padding:0pt .7pt 0pt 0pt;width:268.0pt;">
  <p style="color:windowtext;font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
  </td>
  <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:11.85pt;">
  <p style="color:windowtext;font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
  </td>
  <td width="36" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:26.75pt;">
  <p style="color:windowtext;font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
  </td>
  <td width="43" valign="bottom" style="border:none;border-bottom:solid windowtext 1.0pt;padding:0pt .7pt 0pt 0pt;width:32.05pt;">
  <p style="color:windowtext;font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:8.0pt;">Page&nbsp;No.</font></b></p>
  </td>
  <td width="36" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:26.8pt;">
  <p style="color:windowtext;font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
  </td>
 </tr>
 <tr>
  <td width="44" valign="top" style="border:none;padding:0pt .7pt 0pt 0pt;width:33.25pt;">
  <p align="center" style="color:windowtext;margin:0pt 0pt .0001pt;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">4.1</font></p>
  </td>
  <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:11.85pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="419" colspan="3" valign="top" style="padding:0pt .7pt 0pt 0pt;width:314.15pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">2004 Stock Incentive Plan (Attached as
  Exhibit&nbsp;A to the Company&#146;s Definitive Proxy Statement filed with the
  Commission on April&nbsp;4, 2004 incorporated herein by reference)</font></p>
  </td>
  <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:11.85pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="36" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:26.75pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;text-align:right;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="43" valign="top" style="padding:0pt .7pt 0pt 0pt;width:32.05pt;">
  <p align="center" style="color:windowtext;margin:0pt 0pt .0001pt;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">__</font></p>
  </td>
  <td width="36" valign="top" style="padding:0pt .7pt 0pt 0pt;width:26.8pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
 </tr>
 <tr>
  <td width="44" valign="top" style="padding:0pt .7pt 0pt 0pt;width:33.25pt;">
  <p align="center" style="color:windowtext;margin:0pt 0pt .0001pt;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">5.1</font></p>
  </td>
  <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:11.85pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="419" colspan="3" valign="top" style="padding:0pt .7pt 0pt 0pt;width:314.15pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Opinion and Consent of Dewey Ballantine LLP with
  respect to the legality of the securities being registered</font></p>
  </td>
  <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:11.85pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="36" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:26.75pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;text-align:right;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="43" valign="top" style="padding:0pt .7pt 0pt 0pt;width:32.05pt;">
  <p align="center" style="color:windowtext;margin:0pt 0pt .0001pt;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Page&nbsp;7</font></p>
  </td>
  <td width="36" valign="top" style="padding:0pt .7pt 0pt 0pt;width:26.8pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
 </tr>
 <tr>
  <td width="44" valign="top" style="padding:0pt .7pt 0pt 0pt;width:33.25pt;">
  <p align="center" style="color:windowtext;margin:0pt 0pt .0001pt;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">23.1</font></p>
  </td>
  <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:11.85pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="419" colspan="3" valign="top" style="padding:0pt .7pt 0pt 0pt;width:314.15pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Consent of Dewey Ballantine LLP (contained in their
  opinion filed herewith as Exhibit&nbsp;5.1)</font></p>
  </td>
  <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:11.85pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="36" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:26.75pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;text-align:right;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="43" valign="top" style="padding:0pt .7pt 0pt 0pt;width:32.05pt;">
  <p align="center" style="color:windowtext;margin:0pt 0pt .0001pt;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">&#151;</font></p>
  </td>
  <td width="36" valign="top" style="padding:0pt .7pt 0pt 0pt;width:26.8pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
 </tr>
 <tr>
  <td width="44" valign="top" style="padding:0pt .7pt 0pt 0pt;width:33.25pt;">
  <p align="center" style="color:windowtext;margin:0pt 0pt .0001pt;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">23.2</font></p>
  </td>
  <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:11.85pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="419" colspan="3" valign="top" style="padding:0pt .7pt 0pt 0pt;width:314.15pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Consent of PricewaterhouseCoopers LLP</font></p>
  </td>
  <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:11.85pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="36" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:26.75pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;text-align:right;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="43" valign="top" style="padding:0pt .7pt 0pt 0pt;width:32.05pt;">
  <p align="center" style="color:windowtext;margin:0pt 0pt .0001pt;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Page&nbsp;8</font></p>
  </td>
  <td width="36" valign="top" style="padding:0pt .7pt 0pt 0pt;width:26.8pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
 </tr>
 <tr>
  <td width="44" valign="top" style="padding:0pt .7pt 0pt 0pt;width:33.25pt;">
  <p align="center" style="color:windowtext;margin:0pt 0pt .0001pt;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">24.1</font></p>
  </td>
  <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:11.85pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="419" colspan="3" valign="top" style="padding:0pt .7pt 0pt 0pt;width:314.15pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Power of Attorney of directors and certain officers
  of the Company (included in Signature Page)</font></p>
  </td>
  <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:11.85pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="36" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:26.75pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;text-align:right;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="43" valign="top" style="padding:0pt .7pt 0pt 0pt;width:32.05pt;">
  <p align="center" style="color:windowtext;margin:0pt 0pt .0001pt;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">&#151;</font></p>
  </td>
  <td width="36" valign="top" style="padding:0pt .7pt 0pt 0pt;width:26.8pt;">
  <p style="color:windowtext;margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
 </tr>
 <tr height="0">
  <td width="44" style="border:none;"></td>
  <td width="16" style="border:none;"></td>
  <td width="55" style="border:none;"></td>
  <td width="7" style="border:none;"></td>
  <td width="357" style="border:none;"></td>
  <td width="16" style="border:none;"></td>
  <td width="36" style="border:none;"></td>
  <td width="43" style="border:none;"></td>
  <td width="36" style="border:none;"></td>
 </tr>
</table>

<p style="color:windowtext;line-height:1.0pt;margin:0pt 0pt 11.0pt;"><font size="1" face="Times New Roman">&nbsp;</font></p>

<p style="color:windowtext;font-weight:bold;margin:0pt 0pt 6.0pt 10.0pt;page-break-after:avoid;text-indent:-10.0pt;"><a name="Item9_Undertakings__021236"></a><b><font size="2" face="Times New Roman" style="font-size:10.0pt;">Item 9. &#160;Undertakings.</font></b></p>

<p style="color:windowtext;font-family:Times New Roman;font-size:10.0pt;margin:0pt 0pt 6.0pt 40.0pt;text-indent:-20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">a)</font><font size="1" face="Times New Roman" style="font-size:3.0pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font>The undersigned
registrant hereby undertakes:</p>

<p style="color:windowtext;font-family:Times New Roman;font-size:10.0pt;margin:0pt 0pt 6.0pt 60.0pt;text-indent:-20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">(1)</font><font size="1" face="Times New Roman" style="font-size:3.0pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font>To file, during any
period in which offers or sales are being made, a post-effective amendment to
this registration statement:</p>

<p style="color:windowtext;font-family:Times New Roman;font-size:10.0pt;margin:0pt 0pt 6.0pt 80.0pt;text-indent:-20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">(i)</font><font size="1" face="Times New Roman" style="font-size:3.0pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font>To include any
prospectus required by section 10(a)(3)&nbsp;of the Securities Act of 1933;</p>


 <p style="color:windowtext;font-size:10.0pt;margin:24.0pt 0pt .0001pt;text-align:center;"><font face="Times New Roman">3</font></p> <br><hr size="3" width="100%" noshade color="#010101" align="center">

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<p style="color:windowtext;font-family:Times New Roman;font-size:10.0pt;margin:0pt 0pt 6.0pt 80.0pt;text-indent:-20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">(ii)</font><font size="1" face="Times New Roman" style="font-size:3.0pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font>To reflect in the prospectus
any facts or events arising after the effective date of the&#160; registration statement (or the most recent
post-effective amendment thereof) which, individually or in the aggregate,
represent a fundamental change in the information set forth in the registration
statement. Notwithstanding the foregoing, any increase or decrease in volume of
securities offered (if the total dollar value of securities offered would not
exceed that which was registered) and any deviation from the low or high end of
the estimated maximum offering range may be reflected in the form of prospectus
filed with the Commission pursuant to Rule&nbsp;424(b)&nbsp;if, in the
aggregate, the changes in volume and price represent no more than a 20 percent
change in the maximum aggregate offering price set forth in the &#147;Calculation of
Registration Fee&#148; table in the effective registration statement;</p>

<p style="color:windowtext;font-family:Times New Roman;font-size:10.0pt;margin:0pt 0pt 6.0pt 80.0pt;text-indent:-20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">(iii)</font><font size="1" face="Times New Roman" style="font-size:3.0pt;">&#160;&#160;&#160;&#160; </font>To include any material
information with respect to the plan of distribution not previously disclosed
in the registration statement or any material change to such information in the
registration statement; provided, however, that paragraphs (a)(1)(i)&nbsp;and
(a)(1)(ii)&nbsp;do not apply if the registration statement is on Form&nbsp;S-3,
Form&nbsp;S-8 or Form&nbsp;F-3, and the information required to be
included in a post-effective amendment by those paragraphs is contained in
periodic reports filed with or furnished to the Commission by the registrant
pursuant to Section&nbsp;13 or 15(d)&nbsp;of the Securities Exchange Act of
1934 that are incorporated by reference in the registration statement.</p>

<p style="color:windowtext;font-family:Times New Roman;font-size:10.0pt;margin:0pt 0pt 6.0pt 56.0pt;text-indent:-20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">(2)</font><font size="1" face="Times New Roman" style="font-size:3.0pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font>That,
for the purpose of determining any liability under the Securities Act of 1933,
each such post-effective amendment shall be deemed to be a new registration
statement relating to the securities offered therein, and the offering of such
securities at that time shall be deemed to be the initial bona fide offering
thereof.</p>

<p style="color:windowtext;font-family:Times New Roman;font-size:10.0pt;margin:0pt 0pt 6.0pt 56.0pt;text-indent:-20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">(3)</font><font size="1" face="Times New Roman" style="font-size:3.0pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font>To
remove from registration by means of a post-effective amendment any of the
securities being registered which remain unsold at the termination of the
offering.</p>

<p style="color:windowtext;font-family:Times New Roman;font-size:10.0pt;margin:0pt 0pt 6.0pt 40.0pt;text-indent:-20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">b)</font><font size="1" face="Times New Roman" style="font-size:3.0pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font>The
undersigned registrant hereby undertakes that, for purposes of determining any
liability under the Securities Act of 1933, each filing of the Registrant&#146;s
annual report pursuant to Section&nbsp;13(a)&nbsp;or Section&nbsp;15(d)&nbsp;of
the Securities Exchange Act of 1934 that is incorporated by reference in the
Registration Statement shall be deemed to be a new registration statement
relating to the securities offered therein, and the offering of such securities
at that time shall be deemed to be the initial bona fide offering thereof.</p>

<p style="color:windowtext;font-family:Times New Roman;font-size:10.0pt;margin:0pt 0pt 6.0pt 40.0pt;text-indent:-20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">c)</font><font size="1" face="Times New Roman" style="font-size:3.0pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font>Insofar
as indemnification for liabilities arising under the Securities Act of 1933 may
be permitted to directors, officers and controlling persons of the registrant
pursuant to the foregoing provisions, or otherwise, the registrant has been
advised that in the opinion of the&#160;
Securities and Exchange Commission such indemnification is against
public policy as expressed in the Act and is, therefore, unenforceable. In the
event that a claim for indemnification against such liabilities (other than the
payment by the registrant of expenses incurred or paid by a director, officer
or&#160; controlling person of the registrant
in the successful defense of any action, suit or proceeding) is asserted by
such director, officer or controlling person in connection with the securities
being registered, the registrant will, unless in the opinion of its counsel the
matter has been settled by controlling precedent, submit to a court of
appropriate jurisdiction&#160; the question
whether such indemnification by it is against public policy as expressed in the
Act and will be governed&#160; by the final
adjudication of such issue.</p>


 <p style="color:windowtext;font-size:10.0pt;margin:24.0pt 0pt .0001pt;text-align:center;"><font face="Times New Roman">4</font></p>
</div><br><hr size="3" width="100%" noshade color="#010101" align="center">

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<div>

<p style="font-weight:bold;margin:0pt 0pt 7.0pt;page-break-after:avoid;text-align:center;"><a name="Signatures_021641"></a><b><font size="2" face="Times New Roman" style="font-size:10.0pt;">SIGNATURES</font></b></p>

<p style="font-family:Times New Roman;font-size:10.0pt;margin:0pt 0pt 12.0pt;page-break-after:avoid;text-indent:20.0pt;"><i><font size="2" face="Times New Roman" style="font-size:10.0pt;font-style:italic;">The
Registrant</font></i>. &#160;&#160;Pursuant
to the requirements of the Securities Act of 1933, the Registrant certifies
that it has reasonable grounds to believe that it meets all of the requirements
for filing on Form&nbsp;S-8 and has duly caused this Registration Statement to
be signed on its behalf by the undersigned, thereunto duly authorized, in the
City of Gaithersburg, State of Maryland, on the 14th day of June, 2005.</p>

<table border="0" cellspacing="0" cellpadding="0" style="border-collapse:collapse;">
 <tr>
  <td width="280" valign="top" style="padding:0pt .7pt 0pt 0pt;width:210.0pt;">
  <p style="font-size:10.0pt;margin:0pt 0pt .0001pt;"></p>
  </td>
  <td width="21" valign="top" style="padding:0pt .7pt 0pt 0pt;width:15.6pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="4" valign="top" style="padding:0pt .7pt 0pt 0pt;width:3.0pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="303" valign="top" style="padding:0pt .7pt 0pt 0pt;width:227.2pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">MEDIMMUNE, INC.</font></p>
  </td>
 </tr>
 <tr>
  <td width="280" valign="top" style="padding:0pt .7pt 0pt 0pt;width:210.0pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">&nbsp;</font></p>
  </td>
  <td width="21" valign="top" style="padding:0pt .7pt 0pt 0pt;width:15.6pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">&nbsp;</font></p>
  </td>
  <td width="4" valign="top" style="padding:0pt .7pt 0pt 0pt;width:3.0pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">&nbsp;</font></p>
  </td>
  <td width="303" valign="top" style="padding:0pt .7pt 0pt 0pt;width:227.2pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">&nbsp;</font></p>
  </td>
 </tr>
 <tr>
  <td width="280" valign="top" style="padding:0pt .7pt 0pt 0pt;width:210.0pt;">
  <p align="right" style="margin:0pt 0pt .0001pt;text-align:right;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="21" valign="top" style="padding:0pt .7pt 0pt 0pt;width:15.6pt;">
  <p align="right" style="margin:0pt 0pt .0001pt;text-align:right;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">By:</font></p>
  </td>
  <td width="4" valign="top" style="padding:0pt .7pt 0pt 0pt;width:3.0pt;">
  <p align="right" style="margin:0pt 0pt .0001pt;text-align:right;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="303" valign="top" style="border:none;border-bottom:solid windowtext 1.0pt;padding:0pt .7pt 0pt 0pt;width:227.2pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">/s/ DAVID M.
  MOTT</font></p>
  </td>
 </tr>
 <tr>
  <td width="280" valign="top" style="padding:0pt .7pt 0pt 0pt;width:210.0pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="21" valign="top" style="padding:0pt .7pt 0pt 0pt;width:15.6pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="4" valign="top" style="padding:0pt .7pt 0pt 0pt;width:3.0pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="303" valign="top" style="border:none;padding:0pt .7pt 0pt 0pt;width:227.2pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">David M. Mott</font></p>
  </td>
 </tr>
 <tr>
  <td width="280" valign="top" style="padding:0pt .7pt 0pt 0pt;width:210.0pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="21" valign="top" style="padding:0pt .7pt 0pt 0pt;width:15.6pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="4" valign="top" style="padding:0pt .7pt 0pt 0pt;width:3.0pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
  </td>
  <td width="303" valign="top" style="padding:0pt .7pt 0pt 0pt;width:227.2pt;">
  <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Chief Executive Officer, President and Vice Chairman</font></p>
  </td>
 </tr>
</table>

<p style="line-height:1.0pt;margin:0pt 0pt 16.0pt;"><font size="1" face="Times New Roman">&nbsp;</font></p>

<p style="font-weight:bold;margin:0pt 0pt 11.0pt;page-break-after:avoid;text-align:center;"><a name="PowerOfAttorney_022040"></a><b><font size="2" face="Times New Roman" style="font-size:10.0pt;">POWER OF ATTORNEY</font></b></p>

<p style="margin:0pt 0pt 7.0pt;text-indent:20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;letter-spacing:-.1pt;">KNOW
ALL PERSONS BY THESE PRESENTS, that each of the persons whose names appear
below constitute and appoint David M. Mott and Lota S. Zoth, and each of them,
as his or her true and lawful attorney-in-fact and agent, with full power of
substitution and resubstitution, for him or her and in his or her name, place
and stead, in any and all capacities, to execute any and all amendments to this
Registration Statement, and to file the same, together with all exhibits
thereto, and other documents in connection therewith, with the Securities and
Exchange Commission, and such other agencies, offices and persons as may be
required by applicable law, granting unto said attorney-in-fact and agent, full
power and authority to do and perform each and every act and thing requisite or
necessary to be done in and about the premises, as fully to all intents and
purposes as he or she might or could do in person, hereby ratifying and
confirming all that each said attorney-in-fact and agent may lawfully do or
cause to be done by virtue hereof.</font></p>

<p style="margin:0pt 0pt 12.0pt;page-break-after:avoid;text-indent:20.0pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Pursuant
to the requirements of the Securities Act of 1933, this Registration Statement
has been signed by the following persons in the capacities and on the dates
indicated.</font></p>

<table border="0" cellspacing="0" cellpadding="0" style="border-collapse:collapse;font-family:Times New Roman;">

  <tr style="page-break-inside:avoid;">
   <td width="46" valign="bottom" style="border:none;border-bottom:solid windowtext 1.0pt;padding:0pt .7pt 0pt 0pt;width:34.65pt;">
   <p align="left" style="font-size:8.0pt;font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:left;">Signature</p>
   </td>
   <td width="7" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:4.9pt;">
   <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
   </td>
   <td width="190" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:142.55pt;">
   <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
   </td>
   <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
   </td>
   <td width="23" valign="bottom" style="border:none;border-bottom:solid windowtext 1.0pt;padding:0pt .7pt 0pt 0pt;width:17.3pt;">
   <p align="left" style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:left;"><b><font size="1" face="Times New Roman" style="font-size:8.0pt;">Title</font></b></p>
   </td>
   <td width="7" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:4.9pt;">
   <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
   </td>
   <td width="224" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:167.75pt;">
   <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
   </td>
   <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p align="left" style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:left;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
   </td>
   <td width="24" valign="bottom" style="border:none;border-bottom:solid windowtext 1.0pt;padding:0pt .7pt 0pt 0pt;width:17.75pt;">
   <p align="left" style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:left;"><b><font size="1" face="Times New Roman" style="font-size:8.0pt;">Date</font></b></p>
   </td>
   <td width="7" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:4.95pt;">
   <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
   </td>
   <td width="58" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:43.35pt;">
   <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
   </td>
  </tr>
  <tr height="8" style="height:6.0pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="8" valign="top" style="border:none;border-bottom:solid windowtext 1.0pt;height:6.0pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">/s/ WAYNE T. HOCKMEYER, PH. D.&nbsp;</font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:6.0pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="253" colspan="3" rowspan="2" valign="top" style="height:6.0pt;padding:0pt .7pt 0pt 0pt;width:189.95pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Chairman of the Board</font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:6.0pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="88" colspan="3" rowspan="2" valign="top" style="height:6.0pt;padding:0pt .7pt 0pt 0pt;width:66.05pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">June&nbsp;14, 2005</font></p>
   </td>
  </tr>
  <tr height="24" style="height:18.0pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="24" valign="top" style="border:none;height:18.0pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Wayne T. Hockmeyer, Ph. D.</font></p>
   </td>
  </tr>
  <tr height="6" style="height:4.2pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="6" valign="top" style="border:none;border-bottom:solid windowtext 1.0pt;height:4.2pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">/s/ DAVID M. MOTT&nbsp;</font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:4.2pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="253" colspan="3" rowspan="2" valign="top" style="height:4.2pt;padding:0pt .7pt 0pt 0pt;width:189.95pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Chief Executive
   Officer, President and Vice Chairman of the Board (Principal Executive
   Officer)</font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:4.2pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="88" colspan="3" rowspan="2" valign="top" style="height:4.2pt;padding:0pt .7pt 0pt 0pt;width:66.05pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">June&nbsp;14, 2005</font></p>
   </td>
  </tr>
  <tr height="33" style="height:24.75pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="33" valign="top" style="border:none;height:24.75pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">David M. Mott</font></p>
   </td>
  </tr>
  <tr height="13" style="height:9.75pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="13" valign="top" style="border:none;border-bottom:solid windowtext 1.0pt;height:9.75pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">/s/ DAVID BALTIMORE, PH. D. </font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:9.75pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="253" colspan="3" rowspan="2" valign="top" style="height:9.75pt;padding:0pt .7pt 0pt 0pt;width:189.95pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Director</font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:9.75pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="88" colspan="3" rowspan="2" valign="top" style="height:9.75pt;padding:0pt .7pt 0pt 0pt;width:66.05pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">June&nbsp;14, 2005</font></p>
   </td>
  </tr>
  <tr height="19" style="height:14.25pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="19" valign="top" style="border:none;height:14.25pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">David Baltimore, Ph. D.</font></p>
   </td>
  </tr>
  <tr height="13" style="height:9.75pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="13" valign="top" style="border:none;border-bottom:solid windowtext 1.0pt;height:9.75pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">/s/ M. JAMES BARRETT, PH. D.</font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:9.75pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="253" colspan="3" rowspan="2" valign="top" style="height:9.75pt;padding:0pt .7pt 0pt 0pt;width:189.95pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Director</font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:9.75pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="88" colspan="3" rowspan="2" valign="top" style="height:9.75pt;padding:0pt .7pt 0pt 0pt;width:66.05pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">June&nbsp;14, 2005</font></p>
   </td>
  </tr>
  <tr height="19" style="height:14.25pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="19" valign="top" style="border:none;height:14.25pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">M. James Barrett, Ph. D.</font></p>
   </td>
  </tr>
  <tr height="14" style="height:10.5pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="14" valign="top" style="border:none;border-bottom:solid windowtext 1.0pt;height:10.5pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">/s/ JAMES H. CAVANAUGH, PH. D. </font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="253" colspan="3" rowspan="2" valign="top" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:189.95pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Director</font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="88" colspan="3" rowspan="2" valign="top" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:66.05pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">June&nbsp;14, 2005</font></p>
   </td>
  </tr>
  <tr height="19" style="height:14.25pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="19" valign="top" style="border:none;height:14.25pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">James H. Cavanaugh, Ph. D.</font></p>
   </td>
  </tr>
  <tr height="14" style="height:10.5pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="14" valign="top" style="border:none;border-bottom:solid windowtext 1.0pt;height:10.5pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">/s/ BARBARA HACKMAN FRANKLIN </font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="253" colspan="3" rowspan="2" valign="top" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:189.95pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Director</font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="88" colspan="3" rowspan="2" valign="top" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:66.05pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">June&nbsp;14, 2005</font></p>
   </td>
  </tr>
  <tr height="19" style="height:14.25pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="19" valign="top" style="border:none;height:14.25pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Barbara Hackman Franklin</font></p>
   </td>
  </tr>
  <tr height="14" style="height:10.5pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="14" valign="top" style="border:none;border-bottom:solid windowtext 1.0pt;height:10.5pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">/s/ GORDON S. MACKLIN </font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="253" colspan="3" rowspan="2" valign="top" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:189.95pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Director</font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="88" colspan="3" rowspan="2" valign="top" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:66.05pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">June&nbsp;14, 2005</font></p>
   </td>
  </tr>
  <tr height="19" style="height:14.25pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="19" valign="top" style="border:none;height:14.25pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Gordon S. Macklin</font></p>
   </td>
  </tr>

</table>


 <p style="font-size:10.0pt;margin:24.0pt 0pt .0001pt;text-align:center;"><font face="Times New Roman">5</font></p> <br><hr size="3" width="100%" noshade color="#010101" align="center">

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<p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">&nbsp;</font></p>

<table border="0" cellspacing="0" cellpadding="0" style="border-collapse:collapse;font-family:Times New Roman;">

  <tr style="page-break-inside:avoid;">
   <td width="46" valign="bottom" style="border:none;border-bottom:solid windowtext 1.0pt;padding:0pt .7pt 0pt 0pt;width:34.65pt;">
   <p align="left" style="font-size:8.0pt;font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:left;">Signature</p>
   </td>
   <td width="7" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:4.9pt;">
   <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
   </td>
   <td width="190" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:142.55pt;">
   <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
   </td>
   <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
   </td>
   <td width="23" valign="bottom" style="border:none;border-bottom:solid windowtext 1.0pt;padding:0pt .7pt 0pt 0pt;width:17.3pt;">
   <p align="left" style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:left;"><b><font size="1" face="Times New Roman" style="font-size:8.0pt;">Title</font></b></p>
   </td>
   <td width="7" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:4.9pt;">
   <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
   </td>
   <td width="224" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:167.75pt;">
   <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
   </td>
   <td width="16" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p align="left" style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:left;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
   </td>
   <td width="24" valign="bottom" style="border:none;border-bottom:solid windowtext 1.0pt;padding:0pt .7pt 0pt 0pt;width:17.75pt;">
   <p align="left" style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:left;"><b><font size="1" face="Times New Roman" style="font-size:8.0pt;">Date</font></b></p>
   </td>
   <td width="7" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:4.95pt;">
   <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
   </td>
   <td width="58" valign="bottom" style="padding:0pt .7pt 0pt 0pt;width:43.35pt;">
   <p style="font-weight:bold;line-height:8.0pt;margin:0pt 0pt .0001pt;text-align:center;"><b><font size="1" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></b></p>
   </td>
  </tr>
  <tr height="14" style="height:10.5pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="14" valign="top" style="border:none;border-bottom:solid windowtext 1.0pt;height:10.5pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">/s/ GEORGE M. MILNE,&nbsp;JR., PH. D.</font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="253" colspan="3" rowspan="2" valign="top" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:189.95pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Director</font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="88" colspan="3" rowspan="2" valign="top" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:66.05pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">June&nbsp;14, 2005</font></p>
   </td>
  </tr>
  <tr height="19" style="height:14.25pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="19" valign="top" style="border:none;height:14.25pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">George M. Milne,&nbsp;Jr., Ph. D.</font></p>
   </td>
  </tr>
  <tr height="14" style="height:10.5pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="14" valign="top" style="border:none;border-bottom:solid windowtext 1.0pt;height:10.5pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">/s/ ELIZABETH WYATT </font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="253" colspan="3" rowspan="2" valign="top" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:189.95pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Director</font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="88" colspan="3" rowspan="2" valign="top" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:66.05pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">June&nbsp;14, 2005</font></p>
   </td>
  </tr>
  <tr height="19" style="height:14.25pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="19" valign="top" style="border:none;height:14.25pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Elizabeth Wyatt</font></p>
   </td>
  </tr>
  <tr height="14" style="height:10.5pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="14" valign="top" style="border:none;border-bottom:solid windowtext 1.0pt;height:10.5pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">/s/ LOTA S. ZOTH </font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="253" colspan="3" rowspan="2" valign="top" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:189.95pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Senior Vice President
   and Chief Financial Officer (Principal Financial Officer)</font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="88" colspan="3" rowspan="2" valign="top" style="height:10.5pt;padding:0pt .7pt 0pt 0pt;width:66.05pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">June&nbsp;14, 2005</font></p>
   </td>
  </tr>
  <tr height="19" style="height:14.25pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="19" valign="top" style="border:none;height:14.25pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Lota S. Zoth</font></p>
   </td>
  </tr>
  <tr height="12" style="height:9.0pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="12" valign="top" style="border:none;border-bottom:solid windowtext 1.0pt;height:9.0pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">/s/ MARK E. SPRING </font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:9.0pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="253" colspan="3" rowspan="2" valign="top" style="height:9.0pt;padding:0pt .7pt 0pt 0pt;width:189.95pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Vice President, Finance
   and Controller (Principal Accounting Officer)</font></p>
   </td>
   <td width="16" rowspan="2" valign="bottom" style="height:9.0pt;padding:0pt .7pt 0pt 0pt;width:11.8pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
   </td>
   <td width="88" colspan="3" rowspan="2" valign="top" style="height:9.0pt;padding:0pt .7pt 0pt 0pt;width:66.05pt;">
   <p style="margin:6.0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">June&nbsp;14, 2005</font></p>
   </td>
  </tr>
  <tr height="21" style="height:15.75pt;page-break-inside:avoid;">
   <td width="243" colspan="3" height="21" valign="top" style="border:none;height:15.75pt;padding:0pt .7pt 0pt 0pt;width:182.1pt;">
   <p style="margin:0pt 0pt .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Mark E. Spring</font></p>
   </td>
  </tr>

</table>

<p style="line-height:1.0pt;margin:0pt 0pt 11.0pt;"><font size="1" face="Times New Roman">&nbsp;</font></p>


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{"company-data": {"conformed-name": "MEDIMMUNE INC /DE", "cik": "0000873591", "assigned-sic": "2836", "irs-number": "521555759", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-125809", "film-number": "05895648"}, "business-address": {"street1": "35 W WATKINS MILL RD", "city": "GAITHERSBURG", "state": "MD", "zip": "20878", "phone": "3014170770"}, "mail-address": {"street1": "35 W WATKINS MILL ROAD", "city": "GAITHERSBURG", "state": "MD", "zip": "20878"}}
As filed with the Securities and Exchange Commission on June 14, 2005
Registration No. 333-_______
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON,
D.C. 20549
FORM S-8
REGISTRATION
STATEMENT UNDER
THE SECURITIES ACT OF 1933
MEDIMMUNE, INC.
(Exact name of registrant as
specified in its charter)
DELAWARE
(State or other jurisdiction
of incorporation or
organization)
One
  MedImmune Way
Gaithersburg, Maryland 20878
(Address of Principal Executive Offices) (Zip Code)
55-1555759
(I.R.S. Employer
Identification No.)
2004
Stock Incentive Plan
(Full Title of the Plan)
David
M. Mott
Chief Executive Officer, President and Vice Chairman
MedImmune, Inc.
One MedImmune Way
Gaithersburg, Maryland 20878
(Name and address of agent
for service)
Telephone number, including
area code, of agent for service:
(301) 398-0000
CALCULATION
OF REGISTRATION FEE
Title of Each Class of
Securities
To Be Registered
Amount
To Be
Registered(1)
Proposed Maximum
Offering Price
Per Share(2)
Proposed Maximum
Aggregate Offering
Price(2)
Amount of
Registration Fee(3)
Common Stock,
  $.01 par value per share
8,000,000
$
26.08
$
208,640,000
$
24,557
(1)
Plus such additional
shares as may be issued by reason of stock splits, stock dividends or similar
transactions.
(2)
Pursuant to Rules 457(h) and
457(c), these prices are estimated solely for the purpose of calculating the
registration fee and are based upon the average of the high and low sales
prices of the Registrant's common stock on the Nasdaq National Market on June 13,
2005.
(3)
Pursuant to Rule 457(p),
the aggregate amount of the registration fee is being offset by $6,139,
representing the dollar amount of the registration fee previously paid by the
Registrant in respect of 2,000,000 unissued shares previously registered on a Form S-8
and with respect to which the offering is complete. Accordingly, the adjusted
registration fee for this Form S-8 is $18,418.
EXPLANATORY STATEMENT
This Form S-8
Registration Statement is being filed with the Securities and Exchange
Commission (the "Commission") by MedImmune, Inc., a Delaware corporation
(the "Company"), in order to register 8,000,000 shares of the Company's common
stock, par value $.01 per share (the "Common Stock"), issuable upon exercise of
stock options (including "incentive stock options"), stock appreciation rights,
restricted stock, stock units and stock awards granted or to be granted under
the Company's 2004 Stock Incentive Plan (the "Plan"). On August 5, 2004,
the Company filed with the Commission a Registration Statement on Form S-8
(Registration No. 333-117963) registering up to 13,000,000 shares of
Common Stock issuable under the Plan (the "Initial Registration Statement").
With the addition of 8,000,000 shares pursuant to this Registration Statement,
the total number of shares now registered for issuance pursuant to the Plan is
21,000,000. Pursuant to General Instruction E of Form S-8, the Company
hereby incorporates by reference in this Registration Statement all contents of
the Prior Registration Statements, including the exhibits thereto.
PART I
INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS
The information specified
in Item 1 and Item 2 of Part I of this Registration Statement on Form S-8
(the "Registration Statement") is omitted from this filing in accordance with
the provisions of Rule 428 under the Securities Act of 1933, as amended.
The documents containing the information specified in Part I will be
delivered to the participants in the plan covered by this Registration
Statement as required by Rule 428.
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item
3.   Incorporation of Documents by
Reference.
The following
documents filed with the Commission are hereby incorporated by reference:
a)
The Registrant's
Annual Report on Form 10-K for the fiscal year ended December 31,
2004, as amended;
b)
The Registrant's
Quarterly Report on Form 10-Q for the quarter ended March 31, 2005;
c)
The Registrant's
Current Reports on Form 8-K filed on February 3, 2005, February 23,
2005, March 3, 2005, April 6, 2005, April 15, 2005, April 21,
2005 and May 24, 2005; and
d)
The description of
the Registrant's Common Stock set forth under the caption "Description of
Capital Stock" in the Registrant's registration statement on Form 8-A
dated April 4, 1991 pursuant to Section 12 of the Securities Exchange
Act of 1934, as amended (the "Exchange Act") including all amendments or
reports filed with the Commission for the purpose of updating such description.
All other documents subsequently filed by the
Registrant pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange
Act prior to the filing of a post-effective amendment which indicates that all
securities offered hereunder have been sold or which deregisters all such
securities then remaining unsold shall be deemed to be incorporated by
reference in this Registration Statement and be a part hereof from the date of
filing of such documents.
Any statement contained
herein or in a document incorporated or deemed to be incorporated by reference
herein shall be deemed to be modified or superseded for purposes of this
Registration Statement to the extent that a statement contained herein or in
any other subsequently filed document which also is
1
or is
deemed to be incorporated by reference herein modifies or supersedes such
earlier statement. Any statement so modified or superseded shall not be deemed,
except as so modified or superseded, to constitute a part of this Registration
Statement.
Item 4.   Description of Securities.
Not applicable.
Item
5.   Interests of Named Experts and Counsel.
The validity of the common
stock issuable under the 2004 Stock Incentive Plan has been passed upon for the
Registrant by Dewey Ballantine LLP, New York, New York. A member of Dewey
Ballantine LLP participating in this matter is the beneficial owner of less
than 1% of the Registrant's common stock.
Item
6.   Indemnification of Directors and Officers.
Subsection (a) of Section 145
of the General Corporation Law of the State of Delaware (the "DGCL") empowers a
corporation to indemnify any person who was or is a party or who is threatened
to be made a party to any threatened, pending or completed action, suit or
proceeding, whether civil, criminal, administrative or investigative (other
than an action by or in the right of the corporation) by reason of the fact
that the person is or was a director, officer, employee or agent of the
corporation, or is or was serving at the request of the corporation as a
director, officer, employee or agent of another corporation, partnership, joint
venture, trust or other enterprise, against expenses (including attorney's
fees), judgments, fines and amounts paid in settlement actually and reasonably incurred
by the person in connection with such action, suit or proceeding if the person
acted in good faith and in a manner the person reasonably believed to be in or
not opposed to the best interests of the corporation, and, with respect to any
criminal action or proceeding, had no reasonable cause to believe the person's
conduct was unlawful.
Subsection (b) of Section 145 of the DGCL
empowers a corporation to indemnify any person who was or is a party or is
threatened to be made a party to any threatened, pending or completed action or
suit by or in the right of the corporation to procure a judgment in its favor
by reason of the fact that the person acted in any of the capacities set forth
above, against expenses (including attorney's fees) actually and reasonably
incurred by the person in connection with the defense or settlement of such
action or suit if the person acted in good faith and in a manner the person
reasonably believed to be in or not opposed to the best interests of the
corporation, and except that no indemnification shall be made in respect of any
claim, issue or matter as to which such person shall have been adjudged to be
liable to the corporation unless and only to the extent that the Court of
Chancery or the court in which such action or suit was brought shall determine
upon application that, despite the adjudication of liability but in view of all
the circumstances of the case, such person is fairly and reasonably entitled to
indemnity for such expenses which the Court of Chancery or such other court
shall deem proper.
Section 145 further provides
that to the extent a present or former director or officer of a corporation has
been successful on the merits or otherwise in the defense of any action, suit
or proceeding referred to in subsections (a) and (b) of Section 145,
or in defense of any claim, issue or matter therein, such person shall be
indemnified against expenses (including attorneys' fees) actually and
reasonably incurred by such person in connection therewith; that
indemnification provided for by Section 145 shall not be deemed exclusive
of any other rights to which the indemnified party may be entitled; the
indemnification provided for by Section 145 shall, unless otherwise
provided when authorized or ratified, continue as to a person who has ceased to
be a director, officer, employee or agent and shall inure to the benefit of the
heirs, executors and administrators of such a person; and empowers the
corporation to purchase and maintain insurance on behalf of any person who is
or was a director, officer, employee or agent of the corporation, or is or was
serving at the request of the corporation as a director, officer, employee or
agent of another corporation, partnership, joint venture,
2
trust
or other enterprise against any liability asserted against such person and
incurred by such person in any such capacity, or arising out of such person's
status as such, whether or not the corporation would have the power to
indemnify such person against such liabilities under Section 145.
In addition, Section 145(g) of the DGCL
provides, in general, that a corporation shall have the power to purchase and
maintain insurance on behalf of any person who is or was a director or officer
of the corporation against any liability asserted against the person in any
such capacity, or arising out of the person's status as such, whether or not
the corporation would have the power to indemnify the person against such
liability under the provisions of the law.
Article IX of the Company's By-laws provides that
the Company shall indemnify its directors and officers to the extent permitted
by Delaware law. The Company provides liability insurance for its directors and
officers which provides for coverage against loss from claims made against
directors and officers in their capacity as such, including liabilities under
Securities Act of 1933, as amended.
Section  102(b)(7) of
the DGCL provides that a certificate of incorporation may contain a provision
eliminating or limiting the personal liability of a director to the corporation
or its stockholders for monetary damages for breach of fiduciary duty as a
director, provided that such provision shall not eliminate or limit the
liability of a director (i) for any breach of the director's duty of
loyalty to the corporation or its stockholders, (ii) for acts or omissions
not in good faith or which involve intentional misconduct or a knowing
violation of law, (iii) under Section 174 of the DGCL, or (iv) for
any transaction from which the director derived an improper personal benefit.
Article EIGHTH of the Company's Certificate of Incorporation limits the
liability of directors to the fullest extent permitted by Section 102(b)(7).
Item
7.   Exemption from Registration Claimed.
Not applicable.
Item 8.   Exhibits.
The
following documents are filed as Exhibits hereto:
Exhibit
Sequentially Numbered
Number
Description
Page No.
4.1
2004 Stock Incentive Plan (Attached as
  Exhibit A to the Company's Definitive Proxy Statement filed with the
  Commission on April 4, 2004 incorporated herein by reference)
__
5.1
Opinion and Consent of Dewey Ballantine LLP with
  respect to the legality of the securities being registered
Page 7
23.1
Consent of Dewey Ballantine LLP (contained in their
  opinion filed herewith as Exhibit 5.1)
—
23.2
Consent of PricewaterhouseCoopers LLP
Page 8
24.1
Power of Attorney of directors and certain officers
  of the Company (included in Signature Page)
—
Item 9.  Undertakings.
a)
The undersigned
registrant hereby undertakes:
(1)
To file, during any
period in which offers or sales are being made, a post-effective amendment to
this registration statement:
(i)
To include any
prospectus required by section 10(a)(3) of the Securities Act of 1933;
3
(ii)
To reflect in the prospectus
any facts or events arising after the effective date of the  registration statement (or the most recent
post-effective amendment thereof) which, individually or in the aggregate,
represent a fundamental change in the information set forth in the registration
statement. Notwithstanding the foregoing, any increase or decrease in volume of
securities offered (if the total dollar value of securities offered would not
exceed that which was registered) and any deviation from the low or high end of
the estimated maximum offering range may be reflected in the form of prospectus
filed with the Commission pursuant to Rule 424(b) if, in the
aggregate, the changes in volume and price represent no more than a 20 percent
change in the maximum aggregate offering price set forth in the "Calculation of
Registration Fee" table in the effective registration statement;
(iii)
To include any material
information with respect to the plan of distribution not previously disclosed
in the registration statement or any material change to such information in the
registration statement; provided, however, that paragraphs (a)(1)(i) and
(a)(1)(ii) do not apply if the registration statement is on Form S-3,
Form S-8 or Form F-3, and the information required to be
included in a post-effective amendment by those paragraphs is contained in
periodic reports filed with or furnished to the Commission by the registrant
pursuant to Section 13 or 15(d) of the Securities Exchange Act of
1934 that are incorporated by reference in the registration statement.
(2)
That,
for the purpose of determining any liability under the Securities Act of 1933,
each such post-effective amendment shall be deemed to be a new registration
statement relating to the securities offered therein, and the offering of such
securities at that time shall be deemed to be the initial bona fide offering
thereof.
(3)
To
remove from registration by means of a post-effective amendment any of the
securities being registered which remain unsold at the termination of the
offering.
b)
The
undersigned registrant hereby undertakes that, for purposes of determining any
liability under the Securities Act of 1933, each filing of the Registrant's
annual report pursuant to Section 13(a) or Section 15(d) of
the Securities Exchange Act of 1934 that is incorporated by reference in the
Registration Statement shall be deemed to be a new registration statement
relating to the securities offered therein, and the offering of such securities
at that time shall be deemed to be the initial bona fide offering thereof.
c)
Insofar
as indemnification for liabilities arising under the Securities Act of 1933 may
be permitted to directors, officers and controlling persons of the registrant
pursuant to the foregoing provisions, or otherwise, the registrant has been
advised that in the opinion of the 
Securities and Exchange Commission such indemnification is against
public policy as expressed in the Act and is, therefore, unenforceable. In the
event that a claim for indemnification against such liabilities (other than the
payment by the registrant of expenses incurred or paid by a director, officer
or  controlling person of the registrant
in the successful defense of any action, suit or proceeding) is asserted by
such director, officer or controlling person in connection with the securities
being registered, the registrant will, unless in the opinion of its counsel the
matter has been settled by controlling precedent, submit to a court of
appropriate jurisdiction  the question
whether such indemnification by it is against public policy as expressed in the
Act and will be governed  by the final
adjudication of such issue.
4
SIGNATURES
The
Registrant
.   Pursuant
to the requirements of the Securities Act of 1933, the Registrant certifies
that it has reasonable grounds to believe that it meets all of the requirements
for filing on Form S-8 and has duly caused this Registration Statement to
be signed on its behalf by the undersigned, thereunto duly authorized, in the
City of Gaithersburg, State of Maryland, on the 14th day of June, 2005.
MEDIMMUNE, INC.
By:
/s/ DAVID M.
  MOTT
David M. Mott
Chief Executive Officer, President and Vice Chairman
POWER OF ATTORNEY
KNOW
ALL PERSONS BY THESE PRESENTS, that each of the persons whose names appear
below constitute and appoint David M. Mott and Lota S. Zoth, and each of them,
as his or her true and lawful attorney-in-fact and agent, with full power of
substitution and resubstitution, for him or her and in his or her name, place
and stead, in any and all capacities, to execute any and all amendments to this
Registration Statement, and to file the same, together with all exhibits
thereto, and other documents in connection therewith, with the Securities and
Exchange Commission, and such other agencies, offices and persons as may be
required by applicable law, granting unto said attorney-in-fact and agent, full
power and authority to do and perform each and every act and thing requisite or
necessary to be done in and about the premises, as fully to all intents and
purposes as he or she might or could do in person, hereby ratifying and
confirming all that each said attorney-in-fact and agent may lawfully do or
cause to be done by virtue hereof.
Pursuant
to the requirements of the Securities Act of 1933, this Registration Statement
has been signed by the following persons in the capacities and on the dates
indicated.
Signature
Title
Date
/s/ WAYNE T. HOCKMEYER, PH. D.
Chairman of the Board
June 14, 2005
Wayne T. Hockmeyer, Ph. D.
/s/ DAVID M. MOTT
Chief Executive
   Officer, President and Vice Chairman of the Board (Principal Executive
   Officer)
June 14, 2005
David M. Mott
/s/ DAVID BALTIMORE, PH. D.
Director
June 14, 2005
David Baltimore, Ph. D.
/s/ M. JAMES BARRETT, PH. D.
Director
June 14, 2005
M. James Barrett, Ph. D.
/s/ JAMES H. CAVANAUGH, PH. D.
Director
June 14, 2005
James H. Cavanaugh, Ph. D.
/s/ BARBARA HACKMAN FRANKLIN
Director
June 14, 2005
Barbara Hackman Franklin
/s/ GORDON S. MACKLIN
Director
June 14, 2005
Gordon S. Macklin
5
Signature
Title
Date
/s/ GEORGE M. MILNE, JR., PH. D.
Director
June 14, 2005
George M. Milne, Jr., Ph. D.
/s/ ELIZABETH WYATT
Director
June 14, 2005
Elizabeth Wyatt
/s/ LOTA S. ZOTH
Senior Vice President
   and Chief Financial Officer (Principal Financial Officer)
June 14, 2005
Lota S. Zoth
/s/ MARK E. SPRING
Vice President, Finance
   and Controller (Principal Accounting Officer)
June 14, 2005
Mark E. Spring
6