<PAGE>   1
    As Filed with the Securities and Exchange Commission on October 24, 2000

                                                       Registration No._________



                UNITED STATES SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM S-8

                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933

                              Calico Commerce, Inc.
             ------------------------------------------------------
             (Exact name of registrant as specified in its charter)

<TABLE>
<CAPTION>
            Delaware                                     77-0373344
---------------------------------           ------------------------------------
<S>                                         <C>
  (State or other jurisdiction              (I.R.S. employer identification no.)
of incorporation or organization)
</TABLE>


                      333 West San Carlos Street, Suite 300
                               San Jose, CA 95110
               ---------------------------------------------------
               (Address of principal executive offices) (Zip code)

                              Calico Commerce, Inc.
                             1997 Stock Option Plan
                     and 2000 Non-Officer Stock Option Plan
                     --------------------------------------
                            (Full title of the plan)

                                 Alan P. Naumann
                              Calico Commerce, Inc.
                      333 West San Carlos Street, Suite 300
                               San Jose, CA 95110
                     ---------------------------------------
                     (Name and address of agent for service)


Telephone number, including area code, of agent for service: (408) 975-7400.


This registration statement shall hereafter become effective in accordance with
Rule 462 promulgated under the Securities Act of 1933, as amended.


<PAGE>   2

<TABLE>
<CAPTION>
-------------------------------------------------------------------------------------------------

                                CALCULATION OF REGISTRATION FEE

-------------------------------------------------------------------------------------------------
                                         Proposed maximum   Proposed maximum
Title of Securities     Amount to be      offering price       aggregate           Amount of
 to be registered(1)    registered(2)      per share(3)      offering price(3)   registration fee
-------------------------------------------------------------------------------------------------
<S>                     <C>              <C>                <C>                  <C>
1997 Stock Option Plan
----------------------
Common Stock                269,050           $2.6094        $   702,059.07
Par Value $0.001

2000 Non-Officer Stock Option Plan
----------------------------------
Common Stock              3,549,669           $9.1627        $32,524,552.15
Par Value $0.001          1,450,331           $2.6094        $ 3,784,493.71


TOTALS                    5,269,050                          $37,011,104.93         $9,770.93
</TABLE>
----------
(1)  The securities to be registered include options to acquire Common Stock.

(2)  Pursuant to Rule 416(a), this registration statement also covers any
additional securities that may be offered or issued in connection with any stock
split, stock dividend or similar transaction.

(3)  Estimated pursuant to Rule 457 solely for purposes of calculating the
registration fee. As to shares subject to outstanding but unexercised options
under the 2000 Non-Officer Stock Option Plan, the price is computed on the basis
of the weighted average exercise price. As to the shares under the 1997 Stock
Option Plan and the remaining shares under the 2000 Non-Officer Stock Option
Plan, the price is based upon the average of the high and low prices of the
Common Stock on October 20, 2000, as reported on the Nasdaq National Market.

<PAGE>   3

                                     PART II

               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT


Item 3. Incorporation of Documents by Reference

     Calico Commerce, Inc. (the "Company") hereby incorporates by reference in
this registration statement the following documents:

     (a) The Company's latest annual report on Form 10-K filed pursuant to
Section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended (the
"Exchange Act"), containing audited financial statements for the Company's
latest fiscal year ended March 31, 2000.

     (b) All other reports filed pursuant to Section 13(a) or 15(d) of the
Exchange Act since the end of the fiscal year covered by the registrant document
referred to in (a) above.

     (c) The description of the Company's Common Stock contained in the
Company's Registration Statement on Form 8-A12G filed on September 23, 1999
under the Exchange Act, including any amendment or report filed for the purpose
of updating such description.

     All documents subsequently filed by the Company pursuant to Sections 13(a),
13(c), 14 and 15(d) of the Exchange Act, prior to the filing of a post-effective
amendment to this registration statement which indicates that all securities
offered hereby have been sold or which deregisters all securities remaining
unsold, shall be deemed to be incorporated by reference in this registration
statement and to be a part hereof from the date of filing of such documents.

Item 4. Description of Securities

     The class of securities to be offered is registered under Section 12 of the
Exchange Act.

Item 5. Interests of Named Experts and Counsel

     Inapplicable.

Item 6. Indemnification of Directors and Officers

     Section 102(b) of the Delaware General Corporation Law authorizes a
corporation to provide in its Certificate of Incorporation that a director of
the corporation shall not be personally liable to corporation or its
stockholders for monetary damages for breach or alleged breach of the director's
"duty of care." While this statute does not change directors' duty of care, it
enables corporations to limit available relief to equitable remedies such as
injunction or rescission. The statute has no effect on a director's duty of
loyalty or liability for acts or omissions not in good faith or involving
intentional misconduct or knowing violations of law, illegal payment of
dividends or stock redemptions or repurchases, or for any transaction from which
the director derives an improper personal benefit. As permitted by the statute,
the Company has adopted provisions in its Certificate of Incorporation which
eliminate to the fullest

<PAGE>   4

extent permissible under Delaware law the personal liability of its directors to
the Company and its stockholders for monetary damages for breach or alleged
breach of their duty of care.

     Section 145 of the General Corporation Law of the State of Delaware
provides for the indemnification of officers, directors, employees and agents of
a corporation. The Bylaws of the Company provide for indemnification of its
directors, officers, employees and agents to the full extent permitted by
Delaware law, including those circumstances in which indemnification would
otherwise be discretionary under Delaware law. The Company's Bylaws also empower
it to enter into indemnification agreements with its directors and officers and
to purchase insurance on behalf of any person whom it is required or permitted
to indemnify. The Company has entered into agreements with its directors and
certain of its executive officers that require the Company to indemnify such
persons to the fullest extent permitted under Delaware law against expenses,
judgments, fines, settlements and other amounts actually and reasonably incurred
(including expenses of a derivative action) in connection with any proceeding,
whether actual or threatened, to which any such person may be made a party by
reason of the fact that such person is or was a director or an executive officer
of the Company or any of its affiliated enterprises. The indemnification
agreements also set forth certain procedures that will apply in the event of a
claim for indemnification thereunder.

     Section 145 of the General Corporation Law of the State of Delaware
provides for indemnification in terms sufficiently broad to indemnify such
individuals, under certain circumstances, for liabilities (including
reimbursement of expenses incurred) arising under the Securities Act.

Item 7. Exemption From Registration Claimed

     Inapplicable.

Item 8. Exhibits

     See Exhibit Index.

Item 9. Undertakings

     The undersigned registrant hereby undertakes:

     (1)  To file, during any period in which offers or sales are being made, a
post-effective amendment to this registration statement:

          (i) To include any prospectus required by Section 10(a)(3) of the
Securities Act;

          (ii) To reflect in the prospectus any facts or events arising after
the effective date of the registration statement (or the most recent
post-effective amendment thereof) which, individually or in the aggregate,
represent a fundamental change in the information set forth in the registration
statement; and

          (iii) To include any material information with respect to the plan of
distribution not previously disclosed in the registration statement or any
material change to such information in the registration statement;

<PAGE>   5

provided, however, that paragraphs (1)(i) and (l)(ii) do not apply if the
information required to be included in a post-effective amendment by those
paragraphs is contained in periodic reports filed by the registrant pursuant to
Section 13 or Section 15(d) of the Exchange Act that are incorporated by
reference in the registration statement.

     (2) That, for the purpose of determining any liability under the Securities
Act, each such post-effective amendment shall be deemed to be a new registration
statement relating to the securities offered therein, and the offering of such
securities at that time shall be deemed to be the initial bona fide offering
thereof.

     (3) To remove from registration by means of a post-effective amendment any
of the securities being registered which remain unsold at the termination of the
offering.

     The undersigned registrant hereby undertakes that, for purposes of
determining any liability under the Securities Act, each filing of the
registrant's annual report pursuant to Section 13(a) or Section 15(d) of the
Exchange Act (and, where applicable, each filing of an employee benefit plan's
annual report pursuant to Section 15(d) of the Exchange Act) that is
incorporated by reference in the registration statement shall be deemed to be a
new registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.

     Insofar as indemnification for liabilities arising under the Securities Act
may be permitted to directors, officers and controlling persons of the
registrant pursuant to the foregoing provisions, or otherwise, the registrant
has been advised that in the opinion of the Securities and Exchange Commission
such indemnification is against public policy as expressed in the Securities Act
and is, therefore, unenforceable. In the event that a claim for indemnification
against such liabilities (other than the payment by the registrant of expenses
incurred or paid by a director, officer or controlling person of the registrant
in the successful defense of any action, suit or proceeding) is asserted by such
director, officer or controlling person in connection with the securities being
registered, the registrant will, unless in the opinion of its counsel the matter
has been settled by controlling precedent, submit to a court of appropriate
jurisdiction the question whether such indemnification by it is against public
policy as expressed in the Securities Act and will be governed by the final
adjudication of such issue.

<PAGE>   6

                                    SIGNATURE

     Pursuant to the requirements of the Securities Act of 1933, as amended, the
registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-8 and has duly caused this registration
statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of San Jose, State of California, on October 24, 2000.


                                        CALICO COMMERCE, INC.

                                        By: /s/ Arthur F. Knapp, Jr.
                                            ------------------------------------
                                            Arthur F. Knapp, Jr.
                                            Vice President and Chief Financial
                                            Officer

<PAGE>   7

                        SIGNATURES AND POWER OF ATTORNEY

     The officers and directors of Calico Commerce , Inc. whose signatures
appear below, hereby constitute and appoint Alan P. Naumann and Arthur F. Knapp,
Jr., and each of them, their true and lawful attorneys and agents, with full
power of substitution, each with power to act alone, to sign and execute on
behalf of the undersigned any amendment or amendments to this registration
statement on Form S-8, and each of the undersigned does hereby ratify and
confirm all that each of said attorney and agent, or their or his substitutes,
shall do or cause to be done by virtue hereof.

     Pursuant to the requirements of the Securities Act of 1933, as amended,
this registration statement has been signed by the following persons in the
capacities and on the dates indicated.

<TABLE>
<CAPTION>
           Signature                               Title                        Date
           ---------                               -----                        ----
<S>                                   <C>                                 <C>



    /s/ Alan P. Naumann               President, Chief Executive          October 24, 2000
---------------------------------     Officer and Director
Alan P. Naumann                       (Principal Executive Officer)



    /s/ Arthur F. Knapp, Jr.          Vice President and Chief            October 24, 2000
---------------------------------     Financial Officer
Arthur F. Knapp, Jr.                  (Principal Financial and
                                      Accounting Officer)


    /s/ Joseph B. Costello            Director                            October 24, 2000
---------------------------------
Joseph B. Costello


    /s/ Joel P. Friedman              Director                            October 24, 2000
---------------------------------
Joel P. Friedman


    /s/ Bernard J. Lacroute           Director                            October 24, 2000
---------------------------------
Bernard J. Lacroute


    /s/ William D. Unger              Director                            October 24, 2000
---------------------------------
William D. Unger
</TABLE>

<PAGE>   8

                                  EXHIBIT INDEX
<TABLE>
<S>      <C>
4.1      Certificate of Incorporation of the Company is incorporated by
         reference to Exhibit 3.1 to the Company's Registration Statement on
         Form S-1 filed with the Securities and Exchange Commission initially on
         July 15, 1999 (No. 333-82907)

4.2      Bylaws of the Company are incorporated by reference to Exhibit 3.2 to
         the Company's Registration Statement on Form S-1 filed with the
         Securities and Exchange Commission initially on July 15, 1999 (No.
         333-82907)

5        Opinion re legality

23.1     Consent of Counsel (included in Exhibit 5)

23.2     Consent of PricewaterhouseCoopers LLP, Independent Accountants

24       Power of Attorney (included in signature pages to this registration
         statement)
</TABLE>
[{"type": "S-8", "sequence": "1", "filename": "f66444s-8.txt", "description": "FORM S-8", "secsgml_size_bytes": 16176}]
{"company-data": {"conformed-name": "CALICO COMMERCE INC/", "cik": "0001081154", "assigned-sic": "7389", "irs-number": "770373344", "state-of-incorporation": "DE", "fiscal-year-end": "0331"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-48528", "film-number": "745016"}, "business-address": {"street1": "333 WEST SAN CARLOS ST STE 300", "city": "SAN JOSE", "state": "CA", "zip": "95110"}, "mail-address": {"street1": "333 WEST SAN CARLOS ST STE 300", "city": "SAN JOSE", "state": "CA", "zip": "95110"}}
1
    As Filed with the Securities and Exchange Commission on October 24, 2000

                                                       Registration No._________

                UNITED STATES SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM S-8

                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933

                              Calico Commerce, Inc.
             ------------------------------------------------------
             (Exact name of registrant as specified in its charter)
Delaware                                     77-0373344
---------------------------------           ------------------------------------
(State or other jurisdiction              (I.R.S. employer identification no.)
of incorporation or organization)
333 West San Carlos Street, Suite 300
                               San Jose, CA 95110
               ---------------------------------------------------
               (Address of principal executive offices) (Zip code)

                              Calico Commerce, Inc.
                             1997 Stock Option Plan
                     and 2000 Non-Officer Stock Option Plan
                     --------------------------------------
                            (Full title of the plan)

                                 Alan P. Naumann
                              Calico Commerce, Inc.
                      333 West San Carlos Street, Suite 300
                               San Jose, CA 95110
                     ---------------------------------------
                     (Name and address of agent for service)

Telephone number, including area code, of agent for service: (408) 975-7400.

This registration statement shall hereafter become effective in accordance with
Rule 462 promulgated under the Securities Act of 1933, as amended.
2
-------------------------------------------------------------------------------------------------

                                CALCULATION OF REGISTRATION FEE

-------------------------------------------------------------------------------------------------
                                         Proposed maximum   Proposed maximum
Title of Securities     Amount to be      offering price       aggregate           Amount of
 to be registered(1)    registered(2)      per share(3)      offering price(3)   registration fee
-------------------------------------------------------------------------------------------------
1997 Stock Option Plan
----------------------
Common Stock                269,050           $2.6094        $   702,059.07
Par Value $0.001

2000 Non-Officer Stock Option Plan
----------------------------------
Common Stock              3,549,669           $9.1627        $32,524,552.15
Par Value $0.001          1,450,331           $2.6094        $ 3,784,493.71

TOTALS                    5,269,050                          $37,011,104.93         $9,770.93
----------
(1)  The securities to be registered include options to acquire Common Stock.

(2)  Pursuant to Rule 416(a), this registration statement also covers any
additional securities that may be offered or issued in connection with any stock
split, stock dividend or similar transaction.

(3)  Estimated pursuant to Rule 457 solely for purposes of calculating the
registration fee. As to shares subject to outstanding but unexercised options
under the 2000 Non-Officer Stock Option Plan, the price is computed on the basis
of the weighted average exercise price. As to the shares under the 1997 Stock
Option Plan and the remaining shares under the 2000 Non-Officer Stock Option
Plan, the price is based upon the average of the high and low prices of the
Common Stock on October 20, 2000, as reported on the Nasdaq National Market.
3

                                     PART II

               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

Item 3. Incorporation of Documents by Reference

     Calico Commerce, Inc. (the "Company") hereby incorporates by reference in
this registration statement the following documents:

     (a) The Company's latest annual report on Form 10-K filed pursuant to
Section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended (the
"Exchange Act"), containing audited financial statements for the Company's
latest fiscal year ended March 31, 2000.

     (b) All other reports filed pursuant to Section 13(a) or 15(d) of the
Exchange Act since the end of the fiscal year covered by the registrant document
referred to in (a) above.

     (c) The description of the Company's Common Stock contained in the
Company's Registration Statement on Form 8-A12G filed on September 23, 1999
under the Exchange Act, including any amendment or report filed for the purpose
of updating such description.

     All documents subsequently filed by the Company pursuant to Sections 13(a),
13(c), 14 and 15(d) of the Exchange Act, prior to the filing of a post-effective
amendment to this registration statement which indicates that all securities
offered hereby have been sold or which deregisters all securities remaining
unsold, shall be deemed to be incorporated by reference in this registration
statement and to be a part hereof from the date of filing of such documents.

Item 4. Description of Securities

     The class of securities to be offered is registered under Section 12 of the
Exchange Act.

Item 5. Interests of Named Experts and Counsel

     Inapplicable.

Item 6. Indemnification of Directors and Officers

     Section 102(b) of the Delaware General Corporation Law authorizes a
corporation to provide in its Certificate of Incorporation that a director of
the corporation shall not be personally liable to corporation or its
stockholders for monetary damages for breach or alleged breach of the director's
"duty of care." While this statute does not change directors' duty of care, it
enables corporations to limit available relief to equitable remedies such as
injunction or rescission. The statute has no effect on a director's duty of
loyalty or liability for acts or omissions not in good faith or involving
intentional misconduct or knowing violations of law, illegal payment of
dividends or stock redemptions or repurchases, or for any transaction from which
the director derives an improper personal benefit. As permitted by the statute,
the Company has adopted provisions in its Certificate of Incorporation which
eliminate to the fullest
4

extent permissible under Delaware law the personal liability of its directors to
the Company and its stockholders for monetary damages for breach or alleged
breach of their duty of care.

     Section 145 of the General Corporation Law of the State of Delaware
provides for the indemnification of officers, directors, employees and agents of
a corporation. The Bylaws of the Company provide for indemnification of its
directors, officers, employees and agents to the full extent permitted by
Delaware law, including those circumstances in which indemnification would
otherwise be discretionary under Delaware law. The Company's Bylaws also empower
it to enter into indemnification agreements with its directors and officers and
to purchase insurance on behalf of any person whom it is required or permitted
to indemnify. The Company has entered into agreements with its directors and
certain of its executive officers that require the Company to indemnify such
persons to the fullest extent permitted under Delaware law against expenses,
judgments, fines, settlements and other amounts actually and reasonably incurred
(including expenses of a derivative action) in connection with any proceeding,
whether actual or threatened, to which any such person may be made a party by
reason of the fact that such person is or was a director or an executive officer
of the Company or any of its affiliated enterprises. The indemnification
agreements also set forth certain procedures that will apply in the event of a
claim for indemnification thereunder.

     Section 145 of the General Corporation Law of the State of Delaware
provides for indemnification in terms sufficiently broad to indemnify such
individuals, under certain circumstances, for liabilities (including
reimbursement of expenses incurred) arising under the Securities Act.

Item 7. Exemption From Registration Claimed

     Inapplicable.

Item 8. Exhibits

     See Exhibit Index.

Item 9. Undertakings

     The undersigned registrant hereby undertakes:

     (1)  To file, during any period in which offers or sales are being made, a
post-effective amendment to this registration statement:

          (i) To include any prospectus required by Section 10(a)(3) of the
Securities Act;

          (ii) To reflect in the prospectus any facts or events arising after
the effective date of the registration statement (or the most recent
post-effective amendment thereof) which, individually or in the aggregate,
represent a fundamental change in the information set forth in the registration
statement; and

          (iii) To include any material information with respect to the plan of
distribution not previously disclosed in the registration statement or any
material change to such information in the registration statement;
5

provided, however, that paragraphs (1)(i) and (l)(ii) do not apply if the
information required to be included in a post-effective amendment by those
paragraphs is contained in periodic reports filed by the registrant pursuant to
Section 13 or Section 15(d) of the Exchange Act that are incorporated by
reference in the registration statement.

     (2) That, for the purpose of determining any liability under the Securities
Act, each such post-effective amendment shall be deemed to be a new registration
statement relating to the securities offered therein, and the offering of such
securities at that time shall be deemed to be the initial bona fide offering
thereof.

     (3) To remove from registration by means of a post-effective amendment any
of the securities being registered which remain unsold at the termination of the
offering.

     The undersigned registrant hereby undertakes that, for purposes of
determining any liability under the Securities Act, each filing of the
registrant's annual report pursuant to Section 13(a) or Section 15(d) of the
Exchange Act (and, where applicable, each filing of an employee benefit plan's
annual report pursuant to Section 15(d) of the Exchange Act) that is
incorporated by reference in the registration statement shall be deemed to be a
new registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.

     Insofar as indemnification for liabilities arising under the Securities Act
may be permitted to directors, officers and controlling persons of the
registrant pursuant to the foregoing provisions, or otherwise, the registrant
has been advised that in the opinion of the Securities and Exchange Commission
such indemnification is against public policy as expressed in the Securities Act
and is, therefore, unenforceable. In the event that a claim for indemnification
against such liabilities (other than the payment by the registrant of expenses
incurred or paid by a director, officer or controlling person of the registrant
in the successful defense of any action, suit or proceeding) is asserted by such
director, officer or controlling person in connection with the securities being
registered, the registrant will, unless in the opinion of its counsel the matter
has been settled by controlling precedent, submit to a court of appropriate
jurisdiction the question whether such indemnification by it is against public
policy as expressed in the Securities Act and will be governed by the final
adjudication of such issue.
6

                                    SIGNATURE

     Pursuant to the requirements of the Securities Act of 1933, as amended, the
registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-8 and has duly caused this registration
statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of San Jose, State of California, on October 24, 2000.

                                        CALICO COMMERCE, INC.

                                        By: /s/ Arthur F. Knapp, Jr.
                                            ------------------------------------
                                            Arthur F. Knapp, Jr.
                                            Vice President and Chief Financial
                                            Officer
7

                        SIGNATURES AND POWER OF ATTORNEY

     The officers and directors of Calico Commerce , Inc. whose signatures
appear below, hereby constitute and appoint Alan P. Naumann and Arthur F. Knapp,
Jr., and each of them, their true and lawful attorneys and agents, with full
power of substitution, each with power to act alone, to sign and execute on
behalf of the undersigned any amendment or amendments to this registration
statement on Form S-8, and each of the undersigned does hereby ratify and
confirm all that each of said attorney and agent, or their or his substitutes,
shall do or cause to be done by virtue hereof.

     Pursuant to the requirements of the Securities Act of 1933, as amended,
this registration statement has been signed by the following persons in the
capacities and on the dates indicated.
Signature                               Title                        Date
           ---------                               -----                        ----
/s/ Alan P. Naumann               President, Chief Executive          October 24, 2000
---------------------------------     Officer and Director
Alan P. Naumann                       (Principal Executive Officer)

    /s/ Arthur F. Knapp, Jr.          Vice President and Chief            October 24, 2000
---------------------------------     Financial Officer
Arthur F. Knapp, Jr.                  (Principal Financial and
                                      Accounting Officer)

    /s/ Joseph B. Costello            Director                            October 24, 2000
---------------------------------
Joseph B. Costello

    /s/ Joel P. Friedman              Director                            October 24, 2000
---------------------------------
Joel P. Friedman

    /s/ Bernard J. Lacroute           Director                            October 24, 2000
---------------------------------
Bernard J. Lacroute

    /s/ William D. Unger              Director                            October 24, 2000
---------------------------------
William D. Unger
8

                                  EXHIBIT INDEX
4.1      Certificate of Incorporation of the Company is incorporated by
         reference to Exhibit 3.1 to the Company's Registration Statement on
         Form S-1 filed with the Securities and Exchange Commission initially on
         July 15, 1999 (No. 333-82907)

4.2      Bylaws of the Company are incorporated by reference to Exhibit 3.2 to
         the Company's Registration Statement on Form S-1 filed with the
         Securities and Exchange Commission initially on July 15, 1999 (No.
         333-82907)

5        Opinion re legality

23.1     Consent of Counsel (included in Exhibit 5)

23.2     Consent of PricewaterhouseCoopers LLP, Independent Accountants

24       Power of Attorney (included in signature pages to this registration
         statement)