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<TITLE>Angiotech Pharmaceuticals, S-8</TITLE>
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<H5 align="left" style="page-break-before:always"><A HREF="#toc">Table of Contents</A></H5><P>

<P align="center"><FONT size="2">As filed with the Securities and Exchange Commission on February&nbsp;7, 2003</FONT>

<DIV align="right"><FONT size="2">Registration No.&nbsp;333-</FONT></DIV>


<P align="center"><FONT size="4">SECURITIES AND EXCHANGE COMMISSION</FONT>

<DIV align="center"><FONT size="3">WASHINGTON, D.C. 20549
</FONT></DIV>
<P align="center"><FONT size="5"><B>FORM S-8</B></FONT>

<DIV align="center"><FONT size="3">REGISTRATION STATEMENT UNDER<BR>
THE SECURITIES ACT OF 1933
</FONT></DIV>
<P align="center"><FONT size="6"><B>ANGIOTECH PHARMACEUTICALS, INC.</B></FONT>

<DIV align="center"><FONT size="2"><I>(Exact Name of Registrant as Specified in its Charter)</I>
</FONT></DIV>
<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="55%">
<TR valign="bottom">
    <TD width="50%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="45%">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD align="center" valign="top"><FONT size="2"><B>British Columbia, Canada</B><BR>
<I>(State or Other Jurisdiction of<BR>
Incorporation or Organization)</I></FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top"><FONT size="2">
<B>98-0226269</B><BR>
<I>(I.R.S. Employer<BR>
Identification No.)</I></FONT></TD>
</TR>
</TABLE>
</CENTER>
<P align="center"><FONT size="2"><B>1618 Station Street, Vancouver, British Columbia, V6A 1B6, Canada</B><BR>
<I>(Address of Principal Executive Offices)</I></FONT>

<P align="center"><FONT size="2"><B>Cohesion Technologies, Inc. Restated 1998 Stock Option Plan<BR>
Cohesion Technologies, Inc. 1998 Directors&#146; Stock Option Plan<BR>
Cohesion Technologies, Inc. 2002 Non-Qualified Stock Option Plan<BR>
Cohesion Technologies, Inc. Stock Option Agreements</B><BR>
<I>(Full Title of the Plan)</I></FONT>

<P align="center"><FONT size="2"><B>Kevin F. Kelly, Esq.<BR>
Heller Ehrman White &#038; McAuliffe LLP<BR>
701 Fifth Avenue, Suite&nbsp;6100<BR>
Seattle, Washington 98104</B><BR>
<I>(Name and Address of Agent For Service)</I></FONT>

<P align="center"><FONT size="2"><B>(206)&nbsp;447-0900</B><BR>
<I>(Telephone Number, Including Area Code, of Agent For Service)</I></FONT>

<P align="center"><FONT size="2"><I>Copy to</I>:</FONT>

<P align="center"><FONT size="2"><B>Kyle V. Guse, Esq.<BR>
Heller Ehrman White &#038; McAuliffe LLP<BR>
275 Middlefield Road<BR>
Menlo Park, California 94025-3506<BR>
Telephone: (650)&nbsp;324-7000<BR>
Facsimile: (650)&nbsp;324-0638</B></FONT>

<P align="center"><FONT size="2">CALCULATION OF REGISTRATION FEE</FONT>

<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="100%">

<TR valign="bottom">
<TD colspan="15">&nbsp;</TD>
</TR>

<TR valign="bottom">
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD nowrap align="center"><FONT size="1"><B>Amount</B></FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD nowrap align="center" colspan="3"><FONT size="1"><B>Proposed Maximum</B></FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD nowrap align="center" colspan="3"><FONT size="1"><B>Proposed Maximum</B></FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD nowrap align="center" colspan="3"><FONT size="1"><B>Amount of</B></FONT></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="center"><FONT size="1"><B>Title of Securities</B></FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD nowrap align="center"><FONT size="1"><B>to be</B></FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD nowrap align="center" colspan="3"><FONT size="1"><B>Offering Price</B></FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD nowrap align="center" colspan="3"><FONT size="1"><B>Aggregate Offering</B></FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD nowrap align="center" colspan="3"><FONT size="1"><B>Registration</B></FONT></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="center"><FONT size="1"><B>to be Registered</B></FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD nowrap align="center"><FONT size="1"><B>Registered (1)</B></FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD nowrap align="center" colspan="3"><FONT size="1"><B>per Share (2)</B></FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD nowrap align="center" colspan="3"><FONT size="1"><B>Price</B></FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD nowrap align="center" colspan="3"><FONT size="1"><B>Fee</B></FONT></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="center" colspan="15"><FONT size="1"><B><HR size="1" width="100%" noshade></B></FONT></TD>

</TR>
<TR valign="bottom">
    <TD width="20%" align="center" valign="top"><FONT size="2">Common Stock, no par value</FONT></TD>
    <TD width="1%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="8%" align="center" valign="top"><FONT size="2">
318,840 (3)
</FONT></TD>
    <TD width="5%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="3%" nowrap align="right" valign="top"><FONT size="2">$</FONT></TD>
    <TD width="7%" align="right" valign="top"><FONT size="2">35.75
</FONT></TD>
    <TD width="3%" valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="5%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="3%" nowrap align="right" valign="top"><FONT size="2">$</FONT></TD>
    <TD width="7%" align="right" valign="top"><FONT size="2">11,398,530
</FONT></TD>
    <TD width="3%" valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="5%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="3%" nowrap align="right" valign="top"><FONT size="2">$</FONT></TD>
    <TD width="7%" align="right" valign="top"><FONT size="2">1,048.67</FONT></TD>
    <TD width="3%" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR valign="bottom">

<TD nowrap align="center" colspan="15"><FONT size="1"><HR size="4" width="100%" noshade></FONT></TD>

</TR>
</TABLE>
</CENTER>
<P>
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR valign="top">
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="1%" align="left" nowrap><FONT size="2">(1)</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="93%"><FONT size="2">Pursuant to Rule&nbsp;416(a). this Registration Statement also covers
any additional securities that may be offered or issued in connection
with any stock split, stock dividend or similar transaction.</FONT></TD>
</TR>
<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR valign="top">
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="1%" align="left" nowrap><FONT size="2">(2)</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="93%"><FONT size="2">Estimated solely for the purpose of computing the amount of the
registration fee pursuant to Rule&nbsp;457(c) under the Securities Act of
1933, as amended, on the basis of the average of the high and low
prices per share of Common Stock of Angiotech Pharmaceuticals, Inc. on
the Nasdaq National Market on February&nbsp;5, 2003.</FONT></TD>
</TR>
<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR valign="top">
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="1%" align="left" nowrap><FONT size="2">(3)</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="93%"><FONT size="2">Registering 249,029 shares for the Cohesion Technologies, Inc.
Restated 1998 Stock Option Plan, 22,968 shares for the Cohesion Technologies,
Inc. 1998 Directors&#146; Stock Option Plan, 16,126 shares for the</FONT></TD>
</TR>
</TABLE>
<P align="center"><FONT size="2">&nbsp;</FONT>
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<H5 align="left" style="page-break-before:always"><A HREF="#toc">Table of Contents</A></H5><P>

<P>
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR valign="top">
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="1%" align="left" nowrap><FONT size="2">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="93%"><FONT size="2">Cohesion Technologies, Inc. 2002 Non-Qualified Stock Option Plan
and 30,717 shares for the Cohesion Technologies, Inc. Stock Option
Agreements.</FONT></TD>
</TR>
</TABLE>
<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<B>Explanatory Note</B>. This Registration Statement on Form&nbsp;S-8 relates to the
issuance of up to 318,840 shares of Common Stock of Angiotech Pharmaceuticals,
Inc. in connection with the assumption by Angiotech Pharmaceuticals, Inc. of
the Cohesion Technologies, Inc. Restated 1998 Stock Option Plan, the Cohesion
Technologies, Inc. 1998 Directors&#146; Stock Option Plan, the Cohesion
Technologies, Inc. 2002 Non-Qualified Stock Option Plan and the Cohesion
Technologies, Inc. Stock Option Agreements. Angiotech Pharmaceuticals, Inc.
assumed the above stated plans in connection with its acquisition of
Cohesion Technologies, Inc. on January&nbsp;31, 2003.
</FONT>

<P align="center"><FONT size="2">&nbsp;</FONT>




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<!-- TOC -->
<A name="toc"><DIV align="CENTER" style="page-break-before:always"><U><B>TABLE OF CONTENTS</B></U></DIV></A>

<P><CENTER>
<TABLE border="0" width="90%" cellpadding="0" cellspacing="0">
<TR>
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	<TD width="76%"></TD>
</TR>
<TR><TD colspan="9"><A HREF="#000">PART II</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#001">Item 3. Incorporation of Documents by Reference</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#002">Item 4. Description of Securities</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#003">Item 5. Interests of Named Experts and Counsel</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#004">Item 6. Indemnification of Directors and Officers</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#005">Item 7. Exemption from Registration Claimed</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#006">Item 8. Exhibits</A></TD></TR>
<TR><TD></TD><TD colspan="8"><A HREF="#007">Item 9. Undertakings</A></TD></TR>
<TR><TD colspan="9"><A HREF="#008">SIGNATURES</A></TD></TR>
<TR><TD colspan="9"><A HREF="#009"> Index to Exhibits</A></TD></TR>
<TR><TD colspan="9"><A HREF="f87448exv5w1.txt">EXHIBIT 5.1</A></TD></TR>
<TR><TD colspan="9"><A HREF="f87448exv23w2.txt">EXHIBIT 23.2</A></TD></TR>
<TR><TD colspan="9"><A HREF="f87448exv99w1.txt">EXHIBIT 99.1</A></TD></TR>
<TR><TD colspan="9"><A HREF="f87448exv99w2.txt">EXHIBIT 99.2</A></TD></TR>
<TR><TD colspan="9"><A HREF="f87448exv99w3.txt">EXHIBIT 99.3</A></TD></TR>
<TR><TD colspan="9"><A HREF="f87448exv99w4.txt">EXHIBIT 99.4</A></TD></TR>
<TR><TD colspan="9"><A HREF="f87448exv99w5.txt">EXHIBIT 99.5</A></TD></TR>
<TR><TD colspan="9"><A HREF="f87448exv99w6.txt">EXHIBIT 99.6</A></TD></TR>
</TABLE>
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<!-- link1 "PART II" -->
<DIV align="left"><A NAME="000"></A></DIV>
<P align="center"><FONT size="2"><B>PART II</B></FONT>
<P align="center"><FONT size="2"><B>INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</B></FONT>
<!-- link2 "Item 3. Incorporation of Documents by Reference" -->
<DIV align="left"><A NAME="001"></A></DIV>

<P align="left"><FONT size="2"><B>Item&nbsp;3. Incorporation of Documents by Reference</B></FONT>

<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The
following documents, which Angiotech
Pharmaceuticals, Inc. (the &#147;Registrant&#148;) has filed with or
submitted to the Securities and Exchange
Commission, are hereby incorporated by reference in this Registration
Statement:
</FONT>

<P>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR valign="top">
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="1%" align="left" nowrap><FONT size="2">(a)</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="93%"><FONT size="2">Registrant&#146;s Annual Report on Form&nbsp;40-F for the fiscal year
ended September&nbsp;30, 2002;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="top">
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="1%" align="left" nowrap><FONT size="2">(b)</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="93%"><FONT size="2">Current Reports of Form&nbsp;6-K
submitted to the Securities and Exchange Commission on October&nbsp;1, 2002, October&nbsp;3,
2002, October&nbsp;7, 2002, October&nbsp;8, 2002, October&nbsp;18,
2002, November&nbsp;20, 2002, December&nbsp;13, 2002, December&nbsp;27, 2002, January&nbsp;7, 2003,
January&nbsp;17, 2003, January&nbsp;21, 2003, January&nbsp;22, 2003, January&nbsp;23,
2003, January&nbsp;31, 2003, February&nbsp;5, 2003 and February&nbsp;6, 2003; and</FONT></TD>
</TR>
<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR valign="top">
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="1%" align="left" nowrap><FONT size="2">(c)</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="93%"><FONT size="2">Registrant&#146;s Registration Statement No.&nbsp;000-30334 on Form
20-FR filed with the Securities and Exchange Commission on October
5, 1999 pursuant to Section&nbsp;12 of the Securities Exchange Act of
1934, as amended (the &#147;Exchange Act&#148;), as amended on Form&nbsp;20-FR/A,
dated November&nbsp;29, 1999, January&nbsp;27, 2000 and February&nbsp;14, 2000 in
which there is described the terms, rights and provisions applicable
to the Registrant&#146;s outstanding Common Stock.</FONT></TD>
</TR>
</TABLE>
<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;All documents subsequently filed pursuant to Section&nbsp;13(a), 13(c), 14 or
15(d) of the Exchange Act and prior to the termination of the offering of the
securities offered hereby shall be deemed to be incorporated by reference into
this registration statement and to be a part hereof from the respective dates
of filing of such documents. Any statement contained in a document
incorporated or deemed to be incorporated by reference herein shall be deemed
to be modified or superseded for purposes of this registration statement to the
extent that a statement contained herein, or in any other subsequently filed
document that also is or is deemed to be incorporated by reference herein,
modifies or supersedes such statement. Any such statement so modified or
superseded shall not be deemed, except as so modified or superseded, to
constitute a part of this registration statement.
</FONT>
<!-- link2 "Item 4. Description of Securities" -->
<DIV align="left"><A NAME="002"></A></DIV>
<P align="left"><FONT size="2"><B>Item&nbsp;4. Description of Securities</B></FONT>
<P>
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR>
    <TD width="3%"></TD>
    <TD width="97%"></TD>
</TR>
<TR valign="top">
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not applicable.</FONT></TD>
</TR>
</TABLE>
<!-- link2 "Item 5. Interests of Named Experts and Counsel" -->
<DIV align="left"><A NAME="003"></A></DIV>
<P align="left"><FONT size="2"><B>Item&nbsp;5. Interests of Named Experts and Counsel</B></FONT>

<P>
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR>
    <TD width="3%"></TD>
    <TD width="97%"></TD>
</TR>
<TR valign="top">
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not applicable.</FONT></TD>
</TR>
</TABLE>
<!-- link2 "Item 6. Indemnification of Directors and Officers" -->
<DIV align="left"><A NAME="004"></A></DIV>
<P align="left"><FONT size="2"><B>Item&nbsp;6. Indemnification of Directors and Officers</B></FONT>

<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Under the Company Act (British Columbia) and the Registrant&#146;s articles,
the Registrant may, with the approval of the British Columbia Supreme Court,
indemnify a present or former director or officer of the Registrant and
indemnify a present or former director or officer of the Registrant and
indemnify an officer, employee or agent who acts or acted at the Registrant&#146;s
request as a director or officer of another corporation of which the Registrant
is or was a stockholder and his or her heirs and legal representatives, against
all costs, charges and expenses, including an amount paid to settle an action
or satisfy a judgment, reasonably incurred by him or her in respect of any
civil, criminal or administrative action or proceeding to which he or she is
made a party by reason of his or her position as a director or officer of the
Registrant or the corporation of which the Registrant is or was a stockholder
if:
</FONT>
<P>
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">
<TR valign="top">
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="1%" align="left" nowrap><FONT size="2">(a)</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="93%"><FONT size="2">he or she acted honestly and in good faith with a view to the best
interests of the Registrant or the corporation of which he or she
is or was a stockholder; and</FONT></TD>
</TR>
<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR valign="top">
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="1%" align="left" nowrap><FONT size="2">(b)</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="93%"><FONT size="2">in the case of a criminal or administrative action or proceeding
that is enforced by a monetary penalty, he or she had reasonable
grounds for believing that his or her conduct was lawful.</FONT></TD>
</TR>
</TABLE>
<P align="center"><FONT size="2">II-1</FONT>
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<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A person is entitled to indemnity from the Registrant upon obtaining an
order from the British Columbia Supreme Court approving such an indemnity. The
Registrant may, with the approval of a court, also indemnify a person in a
derivative action to which that person is made a party by reason of being or
having been a director or officer of the Registrant, if he or she fulfills the
conditions set out in (a)&nbsp;and (b)&nbsp;above.
</FONT>
<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A directors&#146; and officers&#146; liability insurance policy is maintained by the
Registrant, which insures directors and officers of the Registrant and its
subsidiaries for losses as a result of claims based upon the directors&#146; and
officers&#146; acts or omissions, including liabilities arising under the Securities
Act of 1933, as amended (the &#147;Securities Act&#148;). The policy also reimburses the
Registrant for payments made pursuant to the indemnity provisions under the
Company Act (British Columbia) and the Registrant&#146;s articles.
</FONT>
<!-- link2 "Item 7. Exemption from Registration Claimed" -->
<DIV align="left"><A NAME="005"></A></DIV>
<P align="left"><FONT size="2"><B>Item&nbsp;7.&nbsp;Exemption from Registration Claimed</B>
</FONT>
<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="100%">
<TR valign="bottom">
    <TD width="4%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="95%">&nbsp;</TD>
</TR>
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    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Not applicable.</FONT></TD>
</TR>
</TABLE>
</CENTER>
<!-- link2 "Item 8. Exhibits" -->
<DIV align="left"><A NAME="006"></A></DIV>
<P><FONT size="2"><B>Item&nbsp;8.&nbsp;Exhibits</B></FONT>
<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="75%">
<TR valign="bottom">
    <TD width="4%">&nbsp;</TD>
    <TD width="2%">&nbsp;</TD>
    <TD width="94%">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;&nbsp;5.1</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Opinion of Irwin, White &#038; Jennings.</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">23.1</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Consent of Irwin, White &#038; Jennings (filed as part of Exhibit&nbsp;5.1).</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">23.2</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Consent of Ernst &#038; Young LLP, Chartered Accountants.</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">24.1</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Power of Attorney (page II-4).</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">99.1</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Cohesion Technologies, Inc. Restated 1998 Stock Option Plan.</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">99.2</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Cohesion Technologies, Inc. 1998 Directors&#146; Stock Option Plan.</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">99.3</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Cohesion Technologies, Inc. 2002 Non-Qualified Stock Option Plan.</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">99.4</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Cohesion Technologies, Inc. Stock Option Agreement by and between
William G. Mavity and Cohesion Technologies, Inc executed on
September&nbsp;18, 2001.</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">99.5</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Cohesion Technologies, Inc. Stock Option Agreement by and between
James E. Barnes and Cohesion Technologies, Inc. executed on November
26, 2001.</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">99.6</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Cohesion Technologies, Inc. Stock Option Agreement.</FONT></TD>
</TR>
</TABLE>
</CENTER>
<!-- link2 "Item 9. Undertakings" -->
<DIV align="left"><A NAME="007"></A></DIV>
<P align="left"><FONT size="2"><B>Item&nbsp;9.&nbsp;Undertakings</B>
</FONT>
<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
The undersigned registrant hereby undertakes:
</FONT>
<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
To file, during any period in which offers or sales are being made, a
post-effective amendment to this registration statement and to include any
material information with respect to the plan of distribution not previously
disclosed in the registration statement or any material change to such
information in the registration statement.
</FONT>

<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
That, for the purpose of determining any liability under the
Securities Act, each such post-effective amendment shall be deemed to be a new
registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.
</FONT>

<P align="center"><FONT size="2">II-2</FONT>
<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always"><A HREF="#toc">Table of Contents</A></H5><P>

<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
To remove from registration by means of a post-effective amendment any
of the securities being registered which remain unsold at the termination of
the offering.
</FONT>

<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;B.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
The undersigned registrant hereby undertakes that, for purposes of
determining liability under the Securities Act, each filing of the registrant&#146;s
annual report pursuant to Section&nbsp;13(a) or 15(d) of the Exchange Act that is
incorporated by reference in the registration statement shall be deemed to be a
new registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.
</FONT>

<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;C.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
Insofar as indemnification for liabilities arising under the Securities
Act may be permitted to directors, officers and controlling persons of the
registrant pursuant to the provisions described in Item&nbsp;6, or otherwise, the
registrant has been advised that in the opinion of the Securities and Exchange
Commission such indemnification is against public policy as expressed in the
Securities Act and is, therefore, unenforceable. In the event that a claim for
indemnification against such liabilities (other than the payment by the
registrant of expenses incurred or paid by a director, officer or controlling
person of the registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the registrant will, unless in
the opinion of its counsel the matter has been settled by controlling
precedent, submit to a court of appropriate jurisdiction the question whether
such indemnification by it is against public policy as expressed in the
Securities Act and will be governed by the final adjudication of such issue.
</FONT>


<P align="center"><FONT size="2">II-3</FONT>




<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always"><A HREF="#toc">Table of Contents</A></H5><P>
<!-- link1 "SIGNATURES" -->
<DIV align="left"><A NAME="008"></A></DIV>
<P align="center"><FONT size="2"><B>SIGNATURES</B></FONT>
<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act of 1933, the Registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form&nbsp;S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the city of Vancouver, British Columbia, on February&nbsp;7, 2003.
</FONT>
<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="55%">
<TR valign="bottom">
    <TD width="48%" rowspan="8" valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="2%">&nbsp;</TD>
    <TD width="2%">&nbsp;</TD>
    <TD width="50%">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD colspan="3" valign="top" align="left"><FONT size="2">ANGIOTECH PHARMACEUTICALS, INC.</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR valign="bottom">
    <TD align="right" valign="top"><FONT size="2">By:</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
/s/William L. Hunter<br></FONT></TD>
</TR>
<TR>
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
<HR size="1" noshade></FONT></TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
William L. Hunter <br>
Chief Executive Officer and President</FONT></TD>
</TR>
</TABLE>
</CENTER>
<P align="center"><FONT size="2"><B>POWER OF ATTORNEY</B></FONT>
<P align="left"><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Each person whose signature appears below constitutes and appoints William
L. Hunter and David M. Hall his or her true and lawful attorneys in fact and
agents, each acting alone, with full power of substitution and resubstitution,
for him or her and in his name, place and stead, in any and all capacities, to
sign any or all amendments (including post effective amendments) to the
Registration Statement, and to sign any registration statement for the same
offering covered by this Registration Statement that is to be effective upon
filing pursuant to Rule&nbsp;462(b) under the Securities Act of 1933, as amended,
and all post effective amendments thereto, and to file the same, with all
exhibits thereto, and all documents in connection therewith, with the
Securities and Exchange Commission, granting unto said attorneys-in-fact and
agents, full power and authority to do and perform each and every act and thing
requisite and necessary to be done in and about the premises, as fully to all
intents and purposes as he or she might or could do in person, hereby ratifying
and confirming all that said attorneys-in-fact and agents, each acting alone,
or his or her substitute or substitutes, may lawfully do or cause to be done by
virtue hereof.
</FONT>
<TABLE cellspacing="0" border="0" cellpadding="0" width="80%">
<TR valign="bottom">
    <TD width="34%">&nbsp;</TD>
    <TD width="10%">&nbsp;</TD>
    <TD width="56%">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="center"><FONT size="1"><B>Signature</B></FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD nowrap align="center"><FONT size="1"><B>Title</B></FONT></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="center"><HR size="1" noshade></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD nowrap align="center"><HR size="1" noshade></TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><FONT size="2">/s/William L. Hunter
<HR size="1" noshade>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;William L. Hunter</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Chief Executive Officer and President (Principal
Executive Officer)</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">/s/David M. Hall
<HR size="1" noshade>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;David M. Hall</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Chief Financial Officer (Principal Accounting<BR>
Officer)</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">/s/David T. Howard
<HR size="1" noshade>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;David T. Howard</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Chairman</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">/s/Kenneth H. Galbraith
<HR size="1" noshade>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Kenneth H. Galbraith</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Director</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">/s/Donald E. Longenecker
<HR size="1" noshade>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Donald E. Longenecker</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Director</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">/s/John McDermott
<HR size="1" noshade>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;John McDermott</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Director</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">/s/Harley T. Richardson
<HR size="1" noshade>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Harley T. Richardson</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Director</FONT></TD>
</TR>
</TABLE>
<P align="center"><FONT size="2">II-4</FONT>
<P align="center"><FONT size="2"></FONT>




<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always"><A HREF="#toc">Table of Contents</A></H5><P>

<!-- link1 " Index to Exhibits" -->
<DIV align="left"><A NAME="009"></A></DIV>
<CENTER>
<TABLE cellspacing="0" border="0" cellpadding="0" width="75%">
<TR valign="bottom">
    <TD width="9%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="86%">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD nowrap align="center"><FONT size="1"><B>Index to Exhibits</B></FONT></TD>
</TR>
<TR valign="bottom">
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD nowrap align="center"><HR size="1" noshade></TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;&nbsp;5.1</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Opinion of Irwin, White &#038; Jennings.</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">23.1</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Consent of Irwin, White &#038; Jennings (filed as part of Exhibit&nbsp;5.1).</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">23.2</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Consent of Ernst &#038; Young LLP, Chartered Accountants.</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">24.1</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Power of Attorney (page II-4).</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">99.1</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Cohesion Technologies, Inc. Restated 1998 Stock Option Plan.</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">99.2</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Cohesion Technologies, Inc. 1998 Directors&#146; Stock Option Plan.</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">99.3</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Cohesion Technologies, Inc. 2002 Non-Qualified Stock Option Plan.</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">99.4</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Cohesion Technologies, Inc. Stock Option Agreement by and between
William G. Mavity and Cohesion Technologies, Inc executed on
September&nbsp;18, 2001.</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">99.5</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Cohesion Technologies, Inc. Stock Option Agreement by and between
James E. Barnes and Cohesion Technologies, Inc. executed on November
26, 2001.</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><FONT size="2">99.6</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top"><FONT size="2">
Cohesion Technologies, Inc. Stock Option Agreement.</FONT></TD>
</TR>
</TABLE>
</CENTER>

<P align="center">II-5<FONT size="2"></FONT>




</BODY>
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Angiotech Pharmaceuticals, S-8
Table of Contents
As filed with the Securities and Exchange Commission on February 7, 2003
Registration No. 333-
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
FORM S-8
REGISTRATION STATEMENT UNDER
THE SECURITIES ACT OF 1933
ANGIOTECH PHARMACEUTICALS, INC.
(Exact Name of Registrant as Specified in its Charter)
British Columbia, Canada
(State or Other Jurisdiction of
Incorporation or Organization)
98-0226269
(I.R.S. Employer
Identification No.)
1618 Station Street, Vancouver, British Columbia, V6A 1B6, Canada
(Address of Principal Executive Offices)
Cohesion Technologies, Inc. Restated 1998 Stock Option Plan
Cohesion Technologies, Inc. 1998 Directors' Stock Option Plan
Cohesion Technologies, Inc. 2002 Non-Qualified Stock Option Plan
Cohesion Technologies, Inc. Stock Option Agreements
(Full Title of the Plan)
Kevin F. Kelly, Esq.
Heller Ehrman White & McAuliffe LLP
701 Fifth Avenue, Suite 6100
Seattle, Washington 98104
(Name and Address of Agent For Service)
(206) 447-0900
(Telephone Number, Including Area Code, of Agent For Service)
Copy to
:
Kyle V. Guse, Esq.
Heller Ehrman White & McAuliffe LLP
275 Middlefield Road
Menlo Park, California 94025-3506
Telephone: (650) 324-7000
Facsimile: (650) 324-0638
CALCULATION OF REGISTRATION FEE
Amount
Proposed Maximum
Proposed Maximum
Amount of
Title of Securities
to be
Offering Price
Aggregate Offering
Registration
to be Registered
Registered (1)
per Share (2)
Price
Fee
Common Stock, no par value
318,840 (3)
$
35.75
$
11,398,530
$
1,048.67
(1)
Pursuant to Rule 416(a). this Registration Statement also covers
any additional securities that may be offered or issued in connection
with any stock split, stock dividend or similar transaction.
(2)
Estimated solely for the purpose of computing the amount of the
registration fee pursuant to Rule 457(c) under the Securities Act of
1933, as amended, on the basis of the average of the high and low
prices per share of Common Stock of Angiotech Pharmaceuticals, Inc. on
the Nasdaq National Market on February 5, 2003.
(3)
Registering 249,029 shares for the Cohesion Technologies, Inc.
Restated 1998 Stock Option Plan, 22,968 shares for the Cohesion Technologies,
Inc. 1998 Directors' Stock Option Plan, 16,126 shares for the
Table of Contents
Cohesion Technologies, Inc. 2002 Non-Qualified Stock Option Plan
and 30,717 shares for the Cohesion Technologies, Inc. Stock Option
Agreements.
Explanatory Note
. This Registration Statement on Form S-8 relates to the
issuance of up to 318,840 shares of Common Stock of Angiotech Pharmaceuticals,
Inc. in connection with the assumption by Angiotech Pharmaceuticals, Inc. of
the Cohesion Technologies, Inc. Restated 1998 Stock Option Plan, the Cohesion
Technologies, Inc. 1998 Directors' Stock Option Plan, the Cohesion
Technologies, Inc. 2002 Non-Qualified Stock Option Plan and the Cohesion
Technologies, Inc. Stock Option Agreements. Angiotech Pharmaceuticals, Inc.
assumed the above stated plans in connection with its acquisition of
Cohesion Technologies, Inc. on January 31, 2003.
TABLE OF CONTENTS
PART II
Item 3. Incorporation of Documents by Reference
Item 4. Description of Securities
Item 5. Interests of Named Experts and Counsel
Item 6. Indemnification of Directors and Officers
Item 7. Exemption from Registration Claimed
Item 8. Exhibits
Item 9. Undertakings
SIGNATURES
Index to Exhibits
EXHIBIT 5.1
EXHIBIT 23.2
EXHIBIT 99.1
EXHIBIT 99.2
EXHIBIT 99.3
EXHIBIT 99.4
EXHIBIT 99.5
EXHIBIT 99.6
Table of Contents
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 3. Incorporation of Documents by Reference
The
following documents, which Angiotech
Pharmaceuticals, Inc. (the "Registrant") has filed with or
submitted to the Securities and Exchange
Commission, are hereby incorporated by reference in this Registration
Statement:
(a)
Registrant's Annual Report on Form 40-F for the fiscal year
ended September 30, 2002;
(b)
Current Reports of Form 6-K
submitted to the Securities and Exchange Commission on October 1, 2002, October 3,
2002, October 7, 2002, October 8, 2002, October 18,
2002, November 20, 2002, December 13, 2002, December 27, 2002, January 7, 2003,
January 17, 2003, January 21, 2003, January 22, 2003, January 23,
2003, January 31, 2003, February 5, 2003 and February 6, 2003; and
(c)
Registrant's Registration Statement No. 000-30334 on Form
20-FR filed with the Securities and Exchange Commission on October
5, 1999 pursuant to Section 12 of the Securities Exchange Act of
1934, as amended (the "Exchange Act"), as amended on Form 20-FR/A,
dated November 29, 1999, January 27, 2000 and February 14, 2000 in
which there is described the terms, rights and provisions applicable
to the Registrant's outstanding Common Stock.
All documents subsequently filed pursuant to Section 13(a), 13(c), 14 or
15(d) of the Exchange Act and prior to the termination of the offering of the
securities offered hereby shall be deemed to be incorporated by reference into
this registration statement and to be a part hereof from the respective dates
of filing of such documents. Any statement contained in a document
incorporated or deemed to be incorporated by reference herein shall be deemed
to be modified or superseded for purposes of this registration statement to the
extent that a statement contained herein, or in any other subsequently filed
document that also is or is deemed to be incorporated by reference herein,
modifies or supersedes such statement. Any such statement so modified or
superseded shall not be deemed, except as so modified or superseded, to
constitute a part of this registration statement.
Item 4. Description of Securities
Not applicable.
Item 5. Interests of Named Experts and Counsel
Not applicable.
Item 6. Indemnification of Directors and Officers
Under the Company Act (British Columbia) and the Registrant's articles,
the Registrant may, with the approval of the British Columbia Supreme Court,
indemnify a present or former director or officer of the Registrant and
indemnify a present or former director or officer of the Registrant and
indemnify an officer, employee or agent who acts or acted at the Registrant's
request as a director or officer of another corporation of which the Registrant
is or was a stockholder and his or her heirs and legal representatives, against
all costs, charges and expenses, including an amount paid to settle an action
or satisfy a judgment, reasonably incurred by him or her in respect of any
civil, criminal or administrative action or proceeding to which he or she is
made a party by reason of his or her position as a director or officer of the
Registrant or the corporation of which the Registrant is or was a stockholder
if:
(a)
he or she acted honestly and in good faith with a view to the best
interests of the Registrant or the corporation of which he or she
is or was a stockholder; and
(b)
in the case of a criminal or administrative action or proceeding
that is enforced by a monetary penalty, he or she had reasonable
grounds for believing that his or her conduct was lawful.
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A person is entitled to indemnity from the Registrant upon obtaining an
order from the British Columbia Supreme Court approving such an indemnity. The
Registrant may, with the approval of a court, also indemnify a person in a
derivative action to which that person is made a party by reason of being or
having been a director or officer of the Registrant, if he or she fulfills the
conditions set out in (a) and (b) above.
A directors' and officers' liability insurance policy is maintained by the
Registrant, which insures directors and officers of the Registrant and its
subsidiaries for losses as a result of claims based upon the directors' and
officers' acts or omissions, including liabilities arising under the Securities
Act of 1933, as amended (the "Securities Act"). The policy also reimburses the
Registrant for payments made pursuant to the indemnity provisions under the
Company Act (British Columbia) and the Registrant's articles.
Item 7. Exemption from Registration Claimed
Not applicable.
Item 8. Exhibits
5.1
Opinion of Irwin, White & Jennings.
23.1
Consent of Irwin, White & Jennings (filed as part of Exhibit 5.1).
23.2
Consent of Ernst & Young LLP, Chartered Accountants.
24.1
Power of Attorney (page II-4).
99.1
Cohesion Technologies, Inc. Restated 1998 Stock Option Plan.
99.2
Cohesion Technologies, Inc. 1998 Directors' Stock Option Plan.
99.3
Cohesion Technologies, Inc. 2002 Non-Qualified Stock Option Plan.
99.4
Cohesion Technologies, Inc. Stock Option Agreement by and between
William G. Mavity and Cohesion Technologies, Inc executed on
September 18, 2001.
99.5
Cohesion Technologies, Inc. Stock Option Agreement by and between
James E. Barnes and Cohesion Technologies, Inc. executed on November
26, 2001.
99.6
Cohesion Technologies, Inc. Stock Option Agreement.
Item 9. Undertakings
A.     
The undersigned registrant hereby undertakes:
(1)     
To file, during any period in which offers or sales are being made, a
post-effective amendment to this registration statement and to include any
material information with respect to the plan of distribution not previously
disclosed in the registration statement or any material change to such
information in the registration statement.
(2)     
That, for the purpose of determining any liability under the
Securities Act, each such post-effective amendment shall be deemed to be a new
registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.
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(3)     
To remove from registration by means of a post-effective amendment any
of the securities being registered which remain unsold at the termination of
the offering.
B.     
The undersigned registrant hereby undertakes that, for purposes of
determining liability under the Securities Act, each filing of the registrant's
annual report pursuant to Section 13(a) or 15(d) of the Exchange Act that is
incorporated by reference in the registration statement shall be deemed to be a
new registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.
C.     
Insofar as indemnification for liabilities arising under the Securities
Act may be permitted to directors, officers and controlling persons of the
registrant pursuant to the provisions described in Item 6, or otherwise, the
registrant has been advised that in the opinion of the Securities and Exchange
Commission such indemnification is against public policy as expressed in the
Securities Act and is, therefore, unenforceable. In the event that a claim for
indemnification against such liabilities (other than the payment by the
registrant of expenses incurred or paid by a director, officer or controlling
person of the registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the registrant will, unless in
the opinion of its counsel the matter has been settled by controlling
precedent, submit to a court of appropriate jurisdiction the question whether
such indemnification by it is against public policy as expressed in the
Securities Act and will be governed by the final adjudication of such issue.
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SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, the Registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the city of Vancouver, British Columbia, on February 7, 2003.
ANGIOTECH PHARMACEUTICALS, INC.
By:
/s/William L. Hunter
William L. Hunter
Chief Executive Officer and President
POWER OF ATTORNEY
Each person whose signature appears below constitutes and appoints William
L. Hunter and David M. Hall his or her true and lawful attorneys in fact and
agents, each acting alone, with full power of substitution and resubstitution,
for him or her and in his name, place and stead, in any and all capacities, to
sign any or all amendments (including post effective amendments) to the
Registration Statement, and to sign any registration statement for the same
offering covered by this Registration Statement that is to be effective upon
filing pursuant to Rule 462(b) under the Securities Act of 1933, as amended,
and all post effective amendments thereto, and to file the same, with all
exhibits thereto, and all documents in connection therewith, with the
Securities and Exchange Commission, granting unto said attorneys-in-fact and
agents, full power and authority to do and perform each and every act and thing
requisite and necessary to be done in and about the premises, as fully to all
intents and purposes as he or she might or could do in person, hereby ratifying
and confirming all that said attorneys-in-fact and agents, each acting alone,
or his or her substitute or substitutes, may lawfully do or cause to be done by
virtue hereof.
Signature
Title
/s/William L. Hunter
William L. Hunter
Chief Executive Officer and President (Principal
Executive Officer)
/s/David M. Hall
David M. Hall
Chief Financial Officer (Principal Accounting
Officer)
/s/David T. Howard
David T. Howard
Chairman
/s/Kenneth H. Galbraith
Kenneth H. Galbraith
Director
/s/Donald E. Longenecker
Donald E. Longenecker
Director
/s/John McDermott
John McDermott
Director
/s/Harley T. Richardson
Harley T. Richardson
Director
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Index to Exhibits
5.1
Opinion of Irwin, White & Jennings.
23.1
Consent of Irwin, White & Jennings (filed as part of Exhibit 5.1).
23.2
Consent of Ernst & Young LLP, Chartered Accountants.
24.1
Power of Attorney (page II-4).
99.1
Cohesion Technologies, Inc. Restated 1998 Stock Option Plan.
99.2
Cohesion Technologies, Inc. 1998 Directors' Stock Option Plan.
99.3
Cohesion Technologies, Inc. 2002 Non-Qualified Stock Option Plan.
99.4
Cohesion Technologies, Inc. Stock Option Agreement by and between
William G. Mavity and Cohesion Technologies, Inc executed on
September 18, 2001.
99.5
Cohesion Technologies, Inc. Stock Option Agreement by and between
James E. Barnes and Cohesion Technologies, Inc. executed on November
26, 2001.
99.6
Cohesion Technologies, Inc. Stock Option Agreement.
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