Registration No. 333-____
                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                           ---------------------------

                                    FORM S-8

                             REGISTRATION STATEMENT
                                      Under
                           THE SECURITIES ACT OF 1933

                               ------------------

                          AMERICAN ENTERPRISE.COM CORP.
             (Exact name of registrant as specified in its charter)

                Florida                                        59-3248917
    (State or other jurisdiction of                         (I.R.S. Employer
     incorporation or organization)                         Identification No.)
     6800 North Dale Mabry Highway
               Suite 100                                           33514
             Tampa, Florida                                      (Zip Code)
(Address of principal executive offices)

        American Enterprise.com Corp. Legal Services Plan of Compensation
                            (Full title of the plan)

    Dr. Cardwell C. Nuchols, President                        Copy to:
       and Chief Operating Officer
      American Enterprise.com Corp.                        Martin A. Traber
 6800 North Dale Mabry Highway, Suite 100                  Foley & Lardner
           Tampa, Florida 33514                  100 N. Tampa Street, Suite 2700
          Phone: (813) 661-9501                         Tampa, Florida 33602
   (Name, address and telephone number,                    (813) 225-4126
including area code, of agent for service)
                           --------------------------

<TABLE>
                         CALCULATION OF REGISTRATION FEE

<CAPTION>
                                                  Proposed Maximum        Proposed Maximum
Title of Securities to       Amount to be        Offering Price Per      Aggregate Offering         Amount of
     be Registered            Registered                Share                  Price             Registration Fee
------------------------ ---------------------- ---------------------- ----------------------- ---------------------
    <S>                     <C>                       <C>                   <C>                      <C>
     Common Stock,
    $.001 par value         100,000 shares            $7.75(1)              $775,000 (1)             $205.00
</TABLE>


                                      -1-
<PAGE>


(1) Estimated pursuant to Rule 457(c) solely for the purpose of calculating the
registration fee. The proposed maximum offering price per share and the proposed
maximum aggregate offering price are based on the average of the high and low
sale prices of Common Stock on the Over The Counter Market on April 17, 2000


                                     PART I


              INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS

         The document or documents containing the information specified in Part
I are not required to be filed with the Securities and Exchange Commission
("Commission") as part of this Form S-8 Registration Statement.


                                     PART II


               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT


Item 3.  Incorporation of Documents by Reference.
         ---------------------------------------

         The following documents have been previously filed by American
Enterprise.com Corp. (the "Company") with the Commission and are incorporated
herein by reference:

         (a)   The Company's Annual Report on Form 10-KSB for the fiscal year
ended December 31, 1999.

         (b)   All other reports filed by the Company pursuant to Section 13(a)
or 15(d) of the Securities Exchange Act of 1934, as amended (the "Exchange
Act"), since December 31, 1999.

         (c)   The description of the Company's Common Stock set forth in
the Registration Statement on Form 8-A, filed with the Commission pursuant to
Section 12 of the Exchange Act, and any amendments or reports filed for the
purpose of updating such description.

         All documents subsequently filed by the Company pursuant to Sections
13(a), 13(c), 14 and 15(d) of the Exchange Act after the date of filing of this
Registration Statement and prior to such time as the Company files a post-
effective amendment to this Registration Statement which indicates that all
securities offered hereby have been sold or which deregisters all securities
then remaining unsold shall be deemed to be incorporated by reference in this
Registration Statement and to be a part hereof from the date of filing of such
documents. Any statement contained in a document incorporated or deemed
incorporated herein by reference shall be deemed to be modified or superceded
for the purpose of this registration statement to the extent that a statement
contained herein or in any subsequently filed document which is also, or is
deemed to be, incorporated herein by reference modifies or supercedes such
statement. Any such statement so modified or superceded shall not be deemed,
except as so modified or superceded, to constitute a part of this registration
statement.


                                      -2-
<PAGE>


Item 4.  Description of Securities.
         -------------------------

         Not applicable.

Item 5.  Interests of Named Experts and Counsel.
         --------------------------------------

         Not applicable.

Item 6.  Indemnification of Directors and Officers.
         -----------------------------------------

         The Florida Business Corporation Act (the "Florida Act") permits a
Florida corporation to indemnify a present or former director or officer of the
corporation (and certain other persons serving at the request of the corporation
in related capacities) for liabilities, including legal expenses, arising by
reason of service in such capacity if such person shall have acted in good faith
and in a manner he reasonably believed to be in or not opposed to the best
interests of the corporation, and in any criminal proceeding if such person had
no reasonable cause to believe his conduct was unlawful. However, in the case of
actions brought by or in the right of the corporation, no indemnification may be
made with respect to any matter as to which such director or officer shall have
been adjudged liable, except in certain limited circumstances.

         The Company's Articles of Incorporation and Bylaws provide that the
Company shall indemnify directors and executive officers consistent with the
Florida Act. In addition, the Company may enter into Indemnification Agreements
with its directors and executive officers in which the Company may agree to
indemnify such persons to the fullest extent now or hereafter permitted by the
Florida Act.

         The Company has a standard policy of directors' and officers' liability
insurance covering directors and officers of the Company with respect to
liabilities incurred as a result of their service in such capacities, which may
extend to, among other things, liability arising under the Securities Act of
1933.

Item 7.  Exemption from Registration Claimed.
         -----------------------------------

         Not Applicable.

Item 8.  Exhibits.
         --------

         The following exhibits have been filed (except where otherwise
indicated) as part of this Registration Statement:

     Exhibit No.                            Exhibit
     ----------                             -------

       (4)             American Enterprise.com Corp. Legal Services Plan of
                       Compensation

       (5)             Opinion of Foley & Lardner.


                                      -3-
<PAGE>


       (23.1)          Consent of Grant Thornton LLP

       (23.2)          Consent of Foley & Lardner (contained in Exhibit 5
                       hereto)

       (24)            Power of Attorney relating to subsequent amendments
                       (included on the signature page to this Registration
                       Statement)

Item 9.  Undertakings.
         ------------

         (a) The undersigned Registrant hereby undertakes:

         (1) To file, during any period in which offers or sales are being made,
a post-effective amendment to this Registration Statement to include any
material information with respect to the plan of distribution not previously
disclosed in the Registration Statement or any material change to such
information in the Registration Statement.

         (2) That, for the purpose of determining any liability under the
Securities Act of 1933, each such post-effective amendment shall be deemed to be
a new registration statement relating to the securities offered herein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.

         (3) To remove from registration by means of a post-effective amendment
any of the securities being registered which remain unsold at the termination of
the offering.

         (b) The undersigned Registrant hereby undertakes that, for purposes of
determining any liability under the Securities Act of 1933, each filing of the
Registrant's annual report pursuant to Section 13(a) or Section 15(d) of the
Securities Exchange Act of 1934 (and, where applicable, each filing of an
employee benefit plan's annual report pursuant to Section 15(d) of the
Securities Exchange Act of 1934) that is incorporated by reference in this
Registration Statement shall be deemed to be a new registration statement
relating to the securities offered herein, and the offering of such securities
at that time shall be deemed to be the initial bona fide offering thereof.

         (c) Insofar as indemnification for liabilities arising under the
Securities Act of 1933 may be permitted to directors, officers and controlling
persons of the Registrant pursuant to the foregoing provisions, or otherwise,
the Registrant has been advised that in the opinion of the Securities and
Exchange Commission such indemnification is against public policy as expressed
in the Act and is, therefore, unenforceable. In the event that a claim for
indemnification against such liabilities (other than the payment by the
Registrant of expenses incurred or paid by a director, officer or controlling
person of the Registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the Registrant will, unless in
the opinion of its counsel the matter has been settled by controlling precedent,
submit to a court of appropriate jurisdiction the question whether such
indemnification by it is against public policy as expressed in the Act and will
be governed by the final adjudication of such issue.


                                      -4-
<PAGE>


                                  SIGNATURES


         Pursuant to the requirements of the Securities Act of 1933, the
Registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of Tampa, and State of Florida, on this 17 day of April,
2000.



                                       AMERICAN ENTERPRISE.COM CORP.



                                       By: /s/ Dr. Cardwell C. Nuchols
                                          --------------------------------------
                                           Dr. Cardwell C. Nuchols, President
                                           and Chief Operating Officer



                                POWER OF ATTORNEY

         Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed below by the following persons in the
capacities and on the dates indicated. Each person whose signature appears below
constitutes and appoints Cardwell C. Nuchols and Curtis L. Alliston, his or her
true and lawful attorney-in-fact and agent, with full power of substitution and
revocation, for him or her and in his or her name, place and stead, in any and
all capacities, to sign any and all amendments (including post-effective
amendments) to this Registration Statement and to file the same, with all
exhibits thereto, and other documents in connection therewith, with the
Securities and Exchange Commission, granting unto said attorneys-in-fact and
agents, and each of them, full power and authority to do and perform each and
every act and thing requisite and necessary to be done in connection therewith,
as fully to all intents and purposes as he or she might or could do in person,
hereby ratifying and confirming all that said attorneys-in-fact and agents, or
either of them, may lawfully do or cause to be done by virtue hereof.


                                      S-1
<PAGE>


<TABLE>
<CAPTION>
           Signature                               Title                                               Date
           ---------                               -----                                               ----

<S>                                         <C>                                                    <C>
/s/ Benedict Maniscalco
------------------------------------
Benedict Maniscalco                         Chairman of the Board                                  April 18, 2000


/s/ Charles Broes
------------------------------------        Chief Executive Officer
Charles Broes                               (Principal Executive Officer)                          April 14, 2000


/s/ Cardwell C. Nuchols                     President, Chief Operating Officer, and
------------------------------------        Director
Cardwell C. Nuchols                         (Principal Financial Officer)                          April 17, 2000


/s/ Curtis L. Alliston
------------------------------------
Curtis L. Alliston                          Secretary & Treasurer                                  April 14, 2000


/s/ James Whitmire
------------------------------------
James Whitmire                              Director                                               April 14, 2000
</TABLE>


                                      S-2
<PAGE>


                                  EXHIBIT INDEX

        AMERICAN ENTERPRISE.COM CORP. LEGAL SERVICES PLAN OF COMPENSATION


       Exhibit No.                                   Exhibit
       -----------                                   -------

           (4)              American Enterprise.com Corp. Legal Services Plan of
                            Compensation

           (5)              Opinion of Foley & Lardner

          (23.1)            Consent of Grant Thornton LLP

          (23.2)            Consent of Foley & Lardner (contained in Exhibit 5
                            hereto)

           (24)             Power of Attorney relating to subsequent amendments
                            (included on the signature page to this Registration
                            Statement)
[{"type": "S-8", "sequence": "1", "description": "FORM S-8 FOR AMERICAN ENTERPRISE.COM CORP.", "secsgml_size_bytes": 15266}]
{"company-data": {"conformed-name": "AMERICAN ENTERPRISE COM CORP", "cik": "0000925894", "assigned-sic": "8071", "irs-number": "593248917", "state-of-incorporation": "FL", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-35198", "film-number": "605375"}, "business-address": {"street1": "6800 NORTH DALE MABRY HIGHWAY", "street2": "SUITE 100", "city": "TAMPA", "state": "FL", "zip": "33514", "phone": "8136619501"}, "mail-address": {"street1": "8800 NORTH DALE MABRY HIGHWAY", "street2": "SUITE 100", "city": "TAMPA", "state": "FL", "zip": "33514"}, "former-company": {"former-conformed-name": "NATIONAL DIAGNOSTICS INC", "date-changed": "19940622"}}
Registration No. 333-____
                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                           ---------------------------

                                    FORM S-8

                             REGISTRATION STATEMENT
                                      Under
                           THE SECURITIES ACT OF 1933

                               ------------------

                          AMERICAN ENTERPRISE.COM CORP.
             (Exact name of registrant as specified in its charter)

                Florida                                        59-3248917
    (State or other jurisdiction of                         (I.R.S. Employer
     incorporation or organization)                         Identification No.)
     6800 North Dale Mabry Highway
               Suite 100                                           33514
             Tampa, Florida                                      (Zip Code)
(Address of principal executive offices)

        American Enterprise.com Corp. Legal Services Plan of Compensation
                            (Full title of the plan)

    Dr. Cardwell C. Nuchols, President                        Copy to:
       and Chief Operating Officer
      American Enterprise.com Corp.                        Martin A. Traber
 6800 North Dale Mabry Highway, Suite 100                  Foley & Lardner
           Tampa, Florida 33514                  100 N. Tampa Street, Suite 2700
          Phone: (813) 661-9501                         Tampa, Florida 33602
   (Name, address and telephone number,                    (813) 225-4126
including area code, of agent for service)
                           --------------------------

                         CALCULATION OF REGISTRATION FEE
Proposed Maximum        Proposed Maximum
Title of Securities to       Amount to be        Offering Price Per      Aggregate Offering         Amount of
     be Registered            Registered                Share                  Price             Registration Fee
------------------------ ---------------------- ---------------------- ----------------------- ---------------------
Common Stock,
    $.001 par value         100,000 shares            $7.75(1)              $775,000 (1)             $205.00
-1-
(1) Estimated pursuant to Rule 457(c) solely for the purpose of calculating the
registration fee. The proposed maximum offering price per share and the proposed
maximum aggregate offering price are based on the average of the high and low
sale prices of Common Stock on the Over The Counter Market on April 17, 2000

                                     PART I

              INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS

         The document or documents containing the information specified in Part
I are not required to be filed with the Securities and Exchange Commission
("Commission") as part of this Form S-8 Registration Statement.

                                     PART II

               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

Item 3.  Incorporation of Documents by Reference.
         ---------------------------------------

         The following documents have been previously filed by American
Enterprise.com Corp. (the "Company") with the Commission and are incorporated
herein by reference:

         (a)   The Company's Annual Report on Form 10-KSB for the fiscal year
ended December 31, 1999.

         (b)   All other reports filed by the Company pursuant to Section 13(a)
or 15(d) of the Securities Exchange Act of 1934, as amended (the "Exchange
Act"), since December 31, 1999.

         (c)   The description of the Company's Common Stock set forth in
the Registration Statement on Form 8-A, filed with the Commission pursuant to
Section 12 of the Exchange Act, and any amendments or reports filed for the
purpose of updating such description.

         All documents subsequently filed by the Company pursuant to Sections
13(a), 13(c), 14 and 15(d) of the Exchange Act after the date of filing of this
Registration Statement and prior to such time as the Company files a post-
effective amendment to this Registration Statement which indicates that all
securities offered hereby have been sold or which deregisters all securities
then remaining unsold shall be deemed to be incorporated by reference in this
Registration Statement and to be a part hereof from the date of filing of such
documents. Any statement contained in a document incorporated or deemed
incorporated herein by reference shall be deemed to be modified or superceded
for the purpose of this registration statement to the extent that a statement
contained herein or in any subsequently filed document which is also, or is
deemed to be, incorporated herein by reference modifies or supercedes such
statement. Any such statement so modified or superceded shall not be deemed,
except as so modified or superceded, to constitute a part of this registration
statement.

                                      -2-
Item 4.  Description of Securities.
         -------------------------

         Not applicable.

Item 5.  Interests of Named Experts and Counsel.
         --------------------------------------

         Not applicable.

Item 6.  Indemnification of Directors and Officers.
         -----------------------------------------

         The Florida Business Corporation Act (the "Florida Act") permits a
Florida corporation to indemnify a present or former director or officer of the
corporation (and certain other persons serving at the request of the corporation
in related capacities) for liabilities, including legal expenses, arising by
reason of service in such capacity if such person shall have acted in good faith
and in a manner he reasonably believed to be in or not opposed to the best
interests of the corporation, and in any criminal proceeding if such person had
no reasonable cause to believe his conduct was unlawful. However, in the case of
actions brought by or in the right of the corporation, no indemnification may be
made with respect to any matter as to which such director or officer shall have
been adjudged liable, except in certain limited circumstances.

         The Company's Articles of Incorporation and Bylaws provide that the
Company shall indemnify directors and executive officers consistent with the
Florida Act. In addition, the Company may enter into Indemnification Agreements
with its directors and executive officers in which the Company may agree to
indemnify such persons to the fullest extent now or hereafter permitted by the
Florida Act.

         The Company has a standard policy of directors' and officers' liability
insurance covering directors and officers of the Company with respect to
liabilities incurred as a result of their service in such capacities, which may
extend to, among other things, liability arising under the Securities Act of
1933.

Item 7.  Exemption from Registration Claimed.
         -----------------------------------

         Not Applicable.

Item 8.  Exhibits.
         --------

         The following exhibits have been filed (except where otherwise
indicated) as part of this Registration Statement:

     Exhibit No.                            Exhibit
     ----------                             -------

       (4)             American Enterprise.com Corp. Legal Services Plan of
                       Compensation

       (5)             Opinion of Foley & Lardner.

                                      -3-
(23.1)          Consent of Grant Thornton LLP

       (23.2)          Consent of Foley & Lardner (contained in Exhibit 5
                       hereto)

       (24)            Power of Attorney relating to subsequent amendments
                       (included on the signature page to this Registration
                       Statement)

Item 9.  Undertakings.
         ------------

         (a) The undersigned Registrant hereby undertakes:

         (1) To file, during any period in which offers or sales are being made,
a post-effective amendment to this Registration Statement to include any
material information with respect to the plan of distribution not previously
disclosed in the Registration Statement or any material change to such
information in the Registration Statement.

         (2) That, for the purpose of determining any liability under the
Securities Act of 1933, each such post-effective amendment shall be deemed to be
a new registration statement relating to the securities offered herein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.

         (3) To remove from registration by means of a post-effective amendment
any of the securities being registered which remain unsold at the termination of
the offering.

         (b) The undersigned Registrant hereby undertakes that, for purposes of
determining any liability under the Securities Act of 1933, each filing of the
Registrant's annual report pursuant to Section 13(a) or Section 15(d) of the
Securities Exchange Act of 1934 (and, where applicable, each filing of an
employee benefit plan's annual report pursuant to Section 15(d) of the
Securities Exchange Act of 1934) that is incorporated by reference in this
Registration Statement shall be deemed to be a new registration statement
relating to the securities offered herein, and the offering of such securities
at that time shall be deemed to be the initial bona fide offering thereof.

         (c) Insofar as indemnification for liabilities arising under the
Securities Act of 1933 may be permitted to directors, officers and controlling
persons of the Registrant pursuant to the foregoing provisions, or otherwise,
the Registrant has been advised that in the opinion of the Securities and
Exchange Commission such indemnification is against public policy as expressed
in the Act and is, therefore, unenforceable. In the event that a claim for
indemnification against such liabilities (other than the payment by the
Registrant of expenses incurred or paid by a director, officer or controlling
person of the Registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the Registrant will, unless in
the opinion of its counsel the matter has been settled by controlling precedent,
submit to a court of appropriate jurisdiction the question whether such
indemnification by it is against public policy as expressed in the Act and will
be governed by the final adjudication of such issue.

                                      -4-
SIGNATURES

         Pursuant to the requirements of the Securities Act of 1933, the
Registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of Tampa, and State of Florida, on this 17 day of April,
2000.

                                       AMERICAN ENTERPRISE.COM CORP.

                                       By: /s/ Dr. Cardwell C. Nuchols
                                          --------------------------------------
                                           Dr. Cardwell C. Nuchols, President
                                           and Chief Operating Officer

                                POWER OF ATTORNEY

         Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed below by the following persons in the
capacities and on the dates indicated. Each person whose signature appears below
constitutes and appoints Cardwell C. Nuchols and Curtis L. Alliston, his or her
true and lawful attorney-in-fact and agent, with full power of substitution and
revocation, for him or her and in his or her name, place and stead, in any and
all capacities, to sign any and all amendments (including post-effective
amendments) to this Registration Statement and to file the same, with all
exhibits thereto, and other documents in connection therewith, with the
Securities and Exchange Commission, granting unto said attorneys-in-fact and
agents, and each of them, full power and authority to do and perform each and
every act and thing requisite and necessary to be done in connection therewith,
as fully to all intents and purposes as he or she might or could do in person,
hereby ratifying and confirming all that said attorneys-in-fact and agents, or
either of them, may lawfully do or cause to be done by virtue hereof.

                                      S-1
Signature                               Title                                               Date
           ---------                               -----                                               ----
/s/ Benedict Maniscalco
------------------------------------
Benedict Maniscalco                         Chairman of the Board                                  April 18, 2000

/s/ Charles Broes
------------------------------------        Chief Executive Officer
Charles Broes                               (Principal Executive Officer)                          April 14, 2000

/s/ Cardwell C. Nuchols                     President, Chief Operating Officer, and
------------------------------------        Director
Cardwell C. Nuchols                         (Principal Financial Officer)                          April 17, 2000

/s/ Curtis L. Alliston
------------------------------------
Curtis L. Alliston                          Secretary & Treasurer                                  April 14, 2000

/s/ James Whitmire
------------------------------------
James Whitmire                              Director                                               April 14, 2000
S-2
EXHIBIT INDEX

        AMERICAN ENTERPRISE.COM CORP. LEGAL SERVICES PLAN OF COMPENSATION

       Exhibit No.                                   Exhibit
       -----------                                   -------

           (4)              American Enterprise.com Corp. Legal Services Plan of
                            Compensation

           (5)              Opinion of Foley & Lardner

          (23.1)            Consent of Grant Thornton LLP

          (23.2)            Consent of Foley & Lardner (contained in Exhibit 5
                            hereto)

           (24)             Power of Attorney relating to subsequent amendments
                            (included on the signature page to this Registration
                            Statement)