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<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">As filed with the United States Securities
and Exchange Commission on March 8, 2012</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: right"><B>Registration No. 333-________</B></P>

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<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">UNITED STATES<BR>
SECURITIES AND EXCHANGE COMMISSION<BR>
Washington, D.C. 20549</P>

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<P STYLE="font: 12pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

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<P STYLE="font: 12pt Times New Roman, Times, Serif; margin: 0; text-align: center">FORM S-8<BR>
REGISTRATION STATEMENT</P>

<P STYLE="font: 12pt Times New Roman, Times, Serif; margin: 0; text-align: center">Under<BR>
THE SECURITIES ACT OF 1933</P>

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<P STYLE="font: 18pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>MAKO Surgical Corp.</B></P>

<P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">(Exact name of registrant as specified in its
charter)</P>

<P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

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    <TD STYLE="width: 50%; font-size: 10pt; text-align: center">Delaware</TD>
    <TD STYLE="width: 50%; font-size: 10pt; text-align: center">20-1901148</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 8pt; text-align: center">(State or Other Jurisdiction of</TD>
    <TD STYLE="font-size: 8pt; text-align: center">(I.R.S. Employer</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 8pt; text-align: center">Incorporation or Organization)</TD>
    <TD STYLE="font-size: 8pt; text-align: center">Identification No.)</TD></TR>
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<P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt/90% Times New Roman, Times, Serif; margin: 0; text-align: center">2555 Davie Road</P>

<P STYLE="font: 12pt/90% Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-size: 10pt">Fort Lauderdale,
Florida 33317<BR>
</FONT><FONT STYLE="font-size: 8pt">(Address, Including Zip Code, of Principal Executive Offices)</FONT></P>

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<P STYLE="font: 14pt/90% Times New Roman, Times, Serif; margin: 0; text-align: center"><B>MAKO Surgical Corp. 2008 Omnibus Incentive
Plan </B></P>

<P STYLE="font: 8pt/90% Times New Roman, Times, Serif; margin: 0; text-align: center">(Full Title of the Plan)</P>

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<P STYLE="font: 10pt/90% Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt/90% Times New Roman, Times, Serif; margin: 0; text-align: center">Maurice R. Ferr&eacute;, M.D.</P>

<P STYLE="font: 10pt/90% Times New Roman, Times, Serif; margin: 0; text-align: center">President and Chief Executive Officer</P>

<P STYLE="font: 10pt/90% Times New Roman, Times, Serif; margin: 0; text-align: center">MAKO Surgical Corp.</P>

<P STYLE="font: 12pt/90% Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-size: 10pt; line-height: 90%">2555
Davie Road, Fort Lauderdale, Florida 33317<BR>
(954) 927-2044</FONT></P>

<P STYLE="font: 10pt/104% Times New Roman, Times, Serif; margin: 0; text-align: center">(Name, Address and Telephone Number, Including
Area Code, of Agent for Service)</P>

<P STYLE="font: 10pt/104% Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt/90% Times New Roman, Times, Serif; margin: 0; text-align: center">COPY TO:<BR>
Jay O. Rothman, Esq.</P>

<P STYLE="font: 10pt/90% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: center">Foley &amp; Lardner LLP<BR>
777 East Wisconsin Avenue<BR>
Milwaukee, Wisconsin 53202<BR>
(414) 271-2400</P>

<P STYLE="font: 8.5pt/90% Times New Roman, Times, Serif; margin: 0 0 3pt; text-align: justify; text-indent: 35.1pt"><FONT STYLE="letter-spacing: -0.1pt">Indicate
by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer or a smaller reporting
company. See the definition of &ldquo;large accelerated filer,&rdquo; &ldquo;accelerated filer&rdquo; and &ldquo;smaller reporting
company&rdquo; in Rule 12b-2 of the Exchange Act. (Check one):</FONT></P>

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    <TD STYLE="width: 26%; font-size: 8.5pt"><FONT STYLE="letter-spacing: -0.1pt">Large accelerated filer <FONT STYLE="font-family: MS Mincho">&#9744;</FONT></FONT></TD>
    <TD STYLE="width: 20%; font-size: 8.5pt"><FONT STYLE="letter-spacing: -0.1pt">Accelerated filer <FONT STYLE="font-family: MS Mincho">&#9746;</FONT></FONT></TD>
    <TD STYLE="width: 30%; font-size: 8.5pt; text-align: center"><FONT STYLE="letter-spacing: -0.1pt">Non-accelerated filer <FONT STYLE="font-family: MS Mincho">&#9744;</FONT></FONT></TD>
    <TD STYLE="width: 24%; font-size: 8.5pt"><FONT STYLE="letter-spacing: -0.1pt">Smaller reporting company <FONT STYLE="font-family: MS Mincho">&#9744;</FONT></FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 8.5pt; text-align: justify">&nbsp;</TD>
    <TD STYLE="font-size: 8.5pt; text-align: justify">&nbsp;</TD>
    <TD STYLE="font-size: 8.5pt; text-align: center">(Do not check if smaller reporting company)</TD>
    <TD STYLE="font-size: 8.5pt; text-align: justify">&nbsp;</TD></TR>
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<P STYLE="font: 12pt Times New Roman, Times, Serif; margin: 0 19.45pt 6pt 0; text-align: center"><B>CALCULATION OF REGISTRATION
FEE</B></P>

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    <TD STYLE="width: 19%; border-top: windowtext 1pt solid; border-bottom: windowtext 1pt solid; padding-top: 1.5pt; padding-bottom: 1.5pt; font-size: 8pt; font-weight: bold">Title of Securities<BR> To Be Registered</TD>
    <TD STYLE="width: 17%; border-top: windowtext 1pt solid; border-bottom: windowtext 1pt solid; padding-top: 1.5pt; padding-bottom: 1.5pt; font-size: 12pt; font-weight: bold"><FONT STYLE="font-size: 8pt"><B>Amount<BR>
To Be Registered</B></FONT><B><FONT STYLE="font-size: 10pt"><SUP>(1)</SUP></FONT></B></TD>
    <TD STYLE="width: 22%; border-top: windowtext 1pt solid; border-bottom: windowtext 1pt solid; padding-top: 1.5pt; padding-bottom: 1.5pt; font-size: 12pt; font-weight: bold"><FONT STYLE="font-size: 8pt"><B>Proposed Maximum<BR>
Offering Price Per Unit</B></FONT><B><FONT STYLE="font-size: 10pt"><SUP>(2)</SUP></FONT></B></TD>
    <TD STYLE="width: 24%; border-top: windowtext 1pt solid; border-bottom: windowtext 1pt solid; padding-top: 1.5pt; padding-bottom: 1.5pt; font-size: 12pt; font-weight: bold"><FONT STYLE="font-size: 8pt"><B>Proposed Maximum<BR>
Aggregate Offering Price</B></FONT><B><FONT STYLE="font-size: 10pt"><SUP>(2)</SUP></FONT></B></TD>
    <TD STYLE="width: 18%; border-top: windowtext 1pt solid; border-bottom: windowtext 1pt solid; padding-top: 1.5pt; padding-bottom: 1.5pt; font-size: 8pt; font-weight: bold">Amount of <BR> Registration Fee</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-bottom: windowtext 1pt solid; padding-top: 1.25pt; padding-bottom: 1.25pt; font-size: 8pt">Common Stock, <BR> par value $0.001 per share&nbsp;</TD>
    <TD STYLE="border-bottom: windowtext 1pt solid; padding-top: 1.25pt; padding-bottom: 1.25pt; font-size: 9pt">1,676,312</TD>
    <TD STYLE="border-bottom: windowtext 1pt solid; padding-top: 1.25pt; padding-bottom: 1.25pt; font-size: 9pt">$39.20</TD>
    <TD STYLE="border-bottom: windowtext 1pt solid; padding-top: 1.25pt; padding-bottom: 1.25pt; font-size: 9pt">$65,711,430.40</TD>
    <TD STYLE="border-bottom: windowtext 1pt solid; padding-top: 1.25pt; padding-bottom: 1.25pt; font-size: 9pt">$7,530.53</TD></TR>
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<P STYLE="font: 3pt Times New Roman, Times, Serif; margin: 0 0.5in 0 63.35pt; text-indent: -27.35pt">&nbsp;</P>

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    <TD STYLE="width: 4%; font-size: 10pt">(1)</TD>
    <TD STYLE="width: 96%; font-size: 10pt">This Registration Statement covers, in addition to the number of shares of Common Stock stated above, options and other rights to purchase or acquire the shares of Common Stock covered by the prospectus of the above-named plan, and, pursuant to Rule 416 under the Securities Act of 1933, as amended (the &ldquo;Securities Act&rdquo;), any additional shares of Common Stock which become issuable under the above-named plan by reason of any stock dividend, stock split, recapitalization or other similar transaction effected without the receipt of consideration which results in an increase in the number of outstanding shares of Common Stock.</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 6pt; font-size: 10pt">(2)</TD>
    <TD STYLE="padding-top: 6pt; font-size: 10pt">Pursuant to Rule 457(h) and (c) promulgated under the Securities Act, the maximum offering price, per share and in the aggregate, and the registration fee were calculated based upon the average of the high and low prices of the Common Stock on March 2, 2012, as reported on the NASDAQ Global Select Market.</TD></TR>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Pursuant to Rule 429 under the Securities Act, the Prospectus referred
to herein also relates to the Registrant&rsquo;s Registration Statements on Form S-8 filed with the Securities and Exchange Commission
on February 28, 2008 (Registration No. 333-149445), March 12, 2009 (Registration No. 333-157889), March 10, 2010 (Registration
No. 333-165386), and March 10, 2011 (Registration No. 333-172732).</P>

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<P STYLE="font: 8pt/90% Times New Roman, Times, Serif; margin: 0 0.5in 6pt 0">&nbsp;</P>

<P STYLE="font: 8pt/90% Times New Roman, Times, Serif; margin: 0 0.5in 6pt 0">&nbsp;</P>

<P STYLE="font: 8pt/90% Times New Roman, Times, Serif; margin: 0 0.5in 6pt 0">&nbsp;</P>

<P STYLE="font: 8pt/90% Times New Roman, Times, Serif; margin: 0 0.5in 6pt 0">&nbsp;</P>

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<P STYLE="font: bold 10pt Times New Roman, Times, Serif; text-align: center; margin-right: 0; margin-left: 0">STATEMENT PURSUANT
TO GENERAL INSTRUCTION E TO FORM S-8</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-right: 0; margin-left: 0">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The
purpose of this Registration Statement is to register 1,676,312 additional shares of Common Stock, $.001 par value per share (&ldquo;Common
Stock&rdquo;), of MAKO Surgical Corp. (the &ldquo;Company&rdquo;) in connection with the MAKO Surgical Corp. 2008 Omnibus Incentive
Plan.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-right: 0; margin-left: 0">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant
to General Instruction E of Form S-8, the contents of the Company&rsquo;s Registration Statements on Form S-8 filed with the Securities
and Exchange Commission on February 28, 2008 (Registration No. 333-149445), March 12, 2009 (Registration No. 333-157889), March
10, 2010 (Registration No. 333-165386), and March 10, 2011 (Registration No. 333-172732), including the documents incorporated
by reference therein, are incorporated by reference into this Registration Statement, except as set forth below.</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; text-align: center; margin-right: 0; margin-left: 0">PART II</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; text-align: center; margin-right: 0; margin-left: 0">INFORMATION REQUIRED
IN THE REGISTRATION STATEMENT</P>

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    <TD STYLE="width: 7%; font-size: 10pt; font-weight: bold">Item 8.</TD>
    <TD STYLE="width: 93%; font-size: 10pt; font-weight: bold"><B><U>Exhibits</U>.</B> </TD></TR>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-right: 0; margin-left: 0">The exhibits filed herewith or incorporated
herein by reference are set forth in the attached Exhibit Index.</P>

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    <TD STYLE="width: 7%; font-size: 10pt; font-weight: bold">Item 9.</TD>
    <TD STYLE="width: 93%; font-size: 10pt; font-weight: bold"><B><U>Undertakings</U>.</B> </TD></TR>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-right: 0; margin-left: 0">(a)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
The undersigned Registrant hereby undertakes:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-right: 0; margin-left: 0">&nbsp;&nbsp;&nbsp;&nbsp;(1)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:</P>

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    <TD STYLE="width: 5%; font-size: 12pt; text-align: right">&nbsp;</TD>
    <TD STYLE="width: 95%; font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;(i)&nbsp;&nbsp;&nbsp;&nbsp; To include any prospectus required by Section 10(a)(3) of the Securities Act of 1933;</TD></TR>
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<P STYLE="font: 12pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

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    <TD STYLE="width: 5%; font-size: 12pt; text-align: right">&nbsp;</TD>
    <TD STYLE="width: 95%; font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;(ii)&nbsp;&nbsp;&nbsp;&nbsp; To reflect in the prospectus any facts or events arising after the effective date of the Registration Statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the Registration Statement;</TD></TR>
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<P STYLE="font: 12pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

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    <TD STYLE="width: 5%; font-size: 12pt; text-align: right">&nbsp;</TD>
    <TD STYLE="width: 95%; font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;(iii)&nbsp;&nbsp;&nbsp;&nbsp; To include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement or any material change to such information in the Registration Statement;</TD></TR>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-right: 0; margin-left: 0"><I>provided, however,</I> that paragraphs
(a)(1)(i) and (a)(1)(ii) do not apply if the information required to be included in a post-effective amendment by those paragraphs
is contained in reports filed with or furnished to the Securities and Exchange Commission by the Registrant pursuant to Section&nbsp;13
or Section&nbsp;15(d) of the Securities Exchange Act of 1934 that are incorporated by reference in the Registration Statement.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-right: 0; margin-left: 0">&nbsp;&nbsp;&nbsp;&nbsp;(2)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
That, for the purpose of determining any liability under the Securities Act of 1933, each such post-effective amendment shall be
deemed to be a new registration statement relating to the securities offered herein, and the offering of such securities at that
time shall be deemed to be the initial bona fide offering thereof.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-right: 0; margin-left: 0">&nbsp;&nbsp;&nbsp;&nbsp;(3)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at
the termination of the offering.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-right: 0; margin-left: 0">&nbsp;&nbsp;&nbsp;&nbsp;(4)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
That, for the purpose of determining liability of the registrant under the Securities Act of 1933 to any purchaser in the initial
distribution of the securities, in a primary offering of securities of the Registrant pursuant to this Registration Statement,
regardless of the underwriting method used to sell the securities to the purchaser, if the securities are offered or sold to such
purchaser by means of any of the following communications, the Registrant will be a seller to the purchaser and will be considered
to offer or sell such securities to such purchaser:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0pt; margin-bottom: 0pt">1</P>

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<P STYLE="font: 12pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

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<TR STYLE="vertical-align: top">
    <TD STYLE="width: 5%; font-size: 12pt; text-align: right">&nbsp;</TD>
    <TD STYLE="width: 95%; font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;(i)&nbsp;&nbsp;&nbsp;&nbsp; Any preliminary prospectus or prospectus of the Registrant relating to the offering required to be filed pursuant to Rule 424 under the Securities Act of 1933;</TD></TR>
</TABLE>
<P STYLE="font: 12pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

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<TR STYLE="vertical-align: top">
    <TD STYLE="width: 5%; font-size: 12pt; text-align: right">&nbsp;</TD>
    <TD STYLE="width: 95%; font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;(ii)&nbsp;&nbsp;&nbsp;&nbsp; Any free writing prospectus relating to the offering prepared by or on behalf of the Registrant or used or referred to by the Registrant;</TD></TR>
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<P STYLE="font: 12pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

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    <TD STYLE="width: 5%; font-size: 12pt; text-align: right">&nbsp;</TD>
    <TD STYLE="width: 95%; font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;(iii)&nbsp;&nbsp;&nbsp;&nbsp; The portion of any other free writing prospectus relating to the offering containing material information about the Registrant or its securities provided by or on behalf of the Registrant; and</TD></TR>
</TABLE>
<P STYLE="font: 12pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

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<TR STYLE="vertical-align: top">
    <TD STYLE="width: 5%; font: 12pt Times New Roman, Times, Serif; text-align: right">&nbsp;</TD>
    <TD STYLE="width: 95%; font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;(iv)&nbsp;&nbsp;&nbsp;&nbsp; Any other communication that is an offer in the offering made by the Registrant to the purchaser.</TD></TR>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-right: 0; margin-left: 0">&nbsp;&nbsp;&nbsp;&nbsp;(b)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
The undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act of 1933,
each filing of the Registrant&rsquo;s annual report pursuant to Section 13(a) or Section 15(d) of the Securities Exchange Act of
1934 that is incorporated by reference in this Registration Statement shall be deemed to be a new registration statement relating
to the securities offered herein, and the offering of such securities at that time shall be deemed to be the initial bona fide
offering thereof.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-right: 0; margin-left: 0">&nbsp;&nbsp;&nbsp;&nbsp;(c)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
Insofar as indemnification for liabilities arising under the Securities Act of 1933 may be permitted to directors, officers and
controlling persons of the Registrant pursuant to the foregoing provisions, or otherwise, the Registrant has been advised that
in the opinion of the Commission such indemnification is against public policy as expressed in the Act and is, therefore, unenforceable.
In the event that a claim for indemnification against such liabilities (other than the payment by the Registrant of expenses incurred
or paid by a director, officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding)
is asserted by such director, officer or controlling person in connection with the securities being registered, the Registrant
will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate
jurisdiction the question whether such indemnification by it is against public policy as expressed in the Act and will be governed
by the final adjudication of such issue.</P>

<P STYLE="font: 12pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">
<FONT STYLE="font-size: 10pt">2</FONT></P>

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<P STYLE="font: bold 10pt Times New Roman, Times, Serif; text-align: center; margin-right: 0; margin-left: 0"><U>SIGNATURES</U></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-right: 0; margin-left: 0">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant
to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets
all of the requirements for filing on Form&nbsp;S-8 and has duly caused this Registration Statement to be signed on its behalf
by the undersigned, thereunto duly authorized, in the City of Fort Lauderdale, State of Florida, on this 8th day of March, 2012.</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="vertical-align: top; font-weight: bold">MAKO Surgical Corp.</TD>
    <TD STYLE="vertical-align: top; font-weight: bold">&nbsp;</TD></TR>
<TR>
    <TD STYLE="width: 60%; vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="width: 3%; vertical-align: top">&nbsp;</TD>
    <TD STYLE="width: 32%; vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="width: 5%; vertical-align: top">&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: top">By:&nbsp;</TD>
    <TD STYLE="border-bottom: windowtext 1pt solid; vertical-align: bottom">/s/ Maurice R. Ferr&eacute;, M.D.</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">Maurice R. Ferr&eacute;, M.D.</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding-left: 9pt; font-style: italic; text-indent: -9pt">President and Chief Executive Officer and<BR> Chairman of the Board</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Each person whose signature appears below constitutes and appoints
Maurice R. Ferr&eacute; and Fritz L. LaPorte, and each of them individually, his true and lawful attorney-in-fact and agent, with
full powers of substitution and resubstitution, for him and in his name, place and stead, in any and all capacities, to sign any
and all amendments (including post-effective amendments) to this Registration Statement, and to file the same, with all exhibits
thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact
and agents, and each of them individually, full power and authority to do and perform each and every act and thing requisite and
necessary to be done in and about the premises, as fully to all intents and purposes as he or she might or could do in person,
hereby ratifying and confirming all that said attorneys-in-fact and agents, or any of them individually, or their substitute or
substitutes, may lawfully do or cause to be done by virtue hereof.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Pursuant to the requirements of the Securities Act, this Registration
Statement has been signed below by the following persons in the capacities indicated below on March 8, 2012.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR>
    <TD STYLE="width: 27%; vertical-align: bottom; font-weight: bold; text-decoration: underline; text-align: center">Signature</TD>
    <TD STYLE="width: 24%; vertical-align: top; font-weight: bold; text-align: center">&nbsp;</TD>
    <TD STYLE="width: 49%; vertical-align: bottom; font-weight: bold; text-decoration: underline; text-align: center">Title</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD></TR>
<TR>
    <TD STYLE="border-bottom: windowtext 1pt solid; vertical-align: bottom">/s/ Maurice R. Ferr&eacute;, M.D.</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD ROWSPAN="2" STYLE="vertical-align: top">
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Chief Executive Officer, President and Chairman of the Board</P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">(Principal Executive Officer)</P></TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">Maurice R. Ferr&eacute;, M.D.</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD></TR>
<TR>
    <TD STYLE="border-bottom: windowtext 1pt solid; vertical-align: bottom">/s/ Fritz L. LaPorte</TD>
    <TD ROWSPAN="2" STYLE="vertical-align: top">&nbsp;</TD>
    <TD ROWSPAN="2" STYLE="vertical-align: bottom">Senior Vice President of Finance and Administration, Chief Financial Officer and Treasurer (Principal&nbsp;Financial Officer and Principal Accounting Officer)</TD></TR>
<TR STYLE="vertical-align: top">
    <TD>Fritz L. LaPorte</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD></TR>
<TR>
    <TD STYLE="border-bottom: windowtext 1pt solid; vertical-align: bottom">/s/ S. Morry Blumenfeld, Ph.D.</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">Director</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">S. Morry Blumenfeld, Ph.D.</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD></TR>
<TR>
    <TD STYLE="border-bottom: windowtext 1pt solid; vertical-align: bottom">/s/ Christopher C. Dewey</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">Director</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">Christopher C. Dewey</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD></TR>
<TR>
    <TD STYLE="border-bottom: windowtext 1pt solid; vertical-align: bottom">/s/ Charles W. Federico</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">Director</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">Charles W. Federico</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD></TR>
<TR>
    <TD STYLE="border-bottom: windowtext 1pt solid; vertical-align: bottom">/s/ John G. Freund, M.D.</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">Director</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">John G. Freund, M.D.</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD></TR>
<TR>
    <TD STYLE="border-bottom: windowtext 1pt solid; vertical-align: bottom">/s/ Frederic H. Moll, M.D.</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">Director</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">Frederic H. Moll, M.D.</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD></TR>
<TR>
    <TD STYLE="border-bottom: windowtext 1pt solid; vertical-align: bottom">/s/ William D. Pruitt</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">Director</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">William D. Pruitt</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD></TR>
<TR>
    <TD STYLE="border-bottom: windowtext 1pt solid; vertical-align: bottom">/s/ Richard R. Pettingill</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: top">Director</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">Richard R. Pettingill</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD></TR>
<TR>
    <TD STYLE="border-bottom: windowtext 1pt solid; vertical-align: bottom">/s/ John J. Savarese, M.D.</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">Director</TD></TR>
<TR>
    <TD STYLE="vertical-align: bottom">John J. Savarese, M.D.</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD></TR>
</TABLE>
<BR>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: center">S-1</P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: center"><A NAME="_Toc190230696"><B>EXHIBIT INDEX</A></B></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR>
    <TD STYLE="width: 11%; vertical-align: top; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center">Exhibit<BR>
<U>Number</U></TD>
    <TD STYLE="width: 89%; vertical-align: bottom; padding-right: 5.4pt; padding-left: 5.4pt; text-decoration: underline; text-align: center">Document Description</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 8pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center">4</TD>
    <TD STYLE="padding-top: 8pt; padding-right: 5.4pt; padding-left: 5.4pt">MAKO Surgical Corp. 2008 Omnibus Incentive Plan (1)</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 8pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center">5</TD>
    <TD STYLE="padding-top: 8pt; padding-right: 5.4pt; padding-left: 5.4pt">Opinion of Foley &amp; Lardner LLP (including consent of counsel) (2)</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 8pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center">23.1</TD>
    <TD STYLE="padding-top: 8pt; padding-right: 5.4pt; padding-left: 5.4pt">Consent of Foley &amp; Lardner LLP (filed as part of Exhibit (5)) (2)</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 8pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center">23.2</TD>
    <TD STYLE="padding-top: 8pt; padding-right: 5.4pt; padding-left: 5.4pt">Consent of Ernst &amp; Young LLP, Independent Registered Public Accounting Firm (2)</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 8pt; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center">24</TD>
    <TD STYLE="padding-top: 8pt; padding-right: 5.4pt; padding-left: 5.4pt">Powers of Attorney (included on the signature page hereto)</TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Documents incorporated by reference to filings made by MAKO Surgical
Corp. under the Securities Exchange Act of 1934, as amended, are under Securities and Exchange Commission (&ldquo;SEC&rdquo;) File
No. 001-33966.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt">____________________________________</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 3%">(1)&nbsp;</TD>
    <TD STYLE="width: 97%">Incorporated by reference to the Registrant&rsquo;s Registration Statement on Form S-1, as amended, filed with the SEC on September 19, 2007 (Registration No. 333-146162).</TD></TR>
<TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD>(2)</TD>
    <TD>Filed herewith.</TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"></P>

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[{"type": "S-8", "sequence": "1", "filename": "mako120986_s8.htm", "description": "FORM S-8", "secsgml_size_bytes": 40719}]
{"company-data": {"conformed-name": "MAKO Surgical Corp.", "cik": "0001411861", "assigned-sic": "3842", "irs-number": "201901148", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-179992", "film-number": "12677897"}, "business-address": {"street1": "2555 DAVIE ROAD", "city": "FT. LAUDERDALE", "state": "FL", "zip": "33317", "phone": "954-927-2044"}, "mail-address": {"street1": "2555 DAVIE ROAD", "city": "FT. LAUDERDALE", "state": "FL", "zip": "33317"}}
As filed with the United States Securities
and Exchange Commission on March 8, 2012
Registration No. 333-________
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-8
REGISTRATION STATEMENT
Under
THE SECURITIES ACT OF 1933
MAKO Surgical Corp.
(Exact name of registrant as specified in its
charter)
Delaware
20-1901148
(State or Other Jurisdiction of
(I.R.S. Employer
Incorporation or Organization)
Identification No.)
2555 Davie Road
Fort Lauderdale,
Florida 33317
(Address, Including Zip Code, of Principal Executive Offices)
MAKO Surgical Corp. 2008 Omnibus Incentive
Plan
(Full Title of the Plan)
Maurice R. Ferré, M.D.
President and Chief Executive Officer
MAKO Surgical Corp.
2555
Davie Road, Fort Lauderdale, Florida 33317
(954) 927-2044
(Name, Address and Telephone Number, Including
Area Code, of Agent for Service)
COPY TO:
Jay O. Rothman, Esq.
Foley & Lardner LLP
777 East Wisconsin Avenue
Milwaukee, Wisconsin 53202
(414) 271-2400
Indicate
by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer or a smaller reporting
company. See the definition of "large accelerated filer," "accelerated filer" and "smaller reporting
company" in Rule 12b-2 of the Exchange Act. (Check one):
Large accelerated filer
☐
Accelerated filer
☒
Non-accelerated filer
☐
Smaller reporting company
☐
(Do not check if smaller reporting company)
CALCULATION OF REGISTRATION
FEE
Title of Securities
To Be Registered
Amount
To Be Registered
(1)
Proposed Maximum
Offering Price Per Unit
(2)
Proposed Maximum
Aggregate Offering Price
(2)
Amount of
Registration Fee
Common Stock,
par value $0.001 per share
1,676,312
$39.20
$65,711,430.40
$7,530.53
(1)
This Registration Statement covers, in addition to the number of shares of Common Stock stated above, options and other rights to purchase or acquire the shares of Common Stock covered by the prospectus of the above-named plan, and, pursuant to Rule 416 under the Securities Act of 1933, as amended (the "Securities Act"), any additional shares of Common Stock which become issuable under the above-named plan by reason of any stock dividend, stock split, recapitalization or other similar transaction effected without the receipt of consideration which results in an increase in the number of outstanding shares of Common Stock.
(2)
Pursuant to Rule 457(h) and (c) promulgated under the Securities Act, the maximum offering price, per share and in the aggregate, and the registration fee were calculated based upon the average of the high and low prices of the Common Stock on March 2, 2012, as reported on the NASDAQ Global Select Market.
Pursuant to Rule 429 under the Securities Act, the Prospectus referred
to herein also relates to the Registrant's Registration Statements on Form S-8 filed with the Securities and Exchange Commission
on February 28, 2008 (Registration No. 333-149445), March 12, 2009 (Registration No. 333-157889), March 10, 2010 (Registration
No. 333-165386), and March 10, 2011 (Registration No. 333-172732).
STATEMENT PURSUANT
TO GENERAL INSTRUCTION E TO FORM S-8
The
purpose of this Registration Statement is to register 1,676,312 additional shares of Common Stock, $.001 par value per share ("Common
Stock"), of MAKO Surgical Corp. (the "Company") in connection with the MAKO Surgical Corp. 2008 Omnibus Incentive
Plan.
Pursuant
to General Instruction E of Form S-8, the contents of the Company's Registration Statements on Form S-8 filed with the Securities
and Exchange Commission on February 28, 2008 (Registration No. 333-149445), March 12, 2009 (Registration No. 333-157889), March
10, 2010 (Registration No. 333-165386), and March 10, 2011 (Registration No. 333-172732), including the documents incorporated
by reference therein, are incorporated by reference into this Registration Statement, except as set forth below.
PART II
INFORMATION REQUIRED
IN THE REGISTRATION STATEMENT
Item 8.
Exhibits
.
The exhibits filed herewith or incorporated
herein by reference are set forth in the attached Exhibit Index.
Item 9.
Undertakings
.
(a)       
The undersigned Registrant hereby undertakes:
(1)       
To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:
(i)     To include any prospectus required by Section 10(a)(3) of the Securities Act of 1933;
(ii)     To reflect in the prospectus any facts or events arising after the effective date of the Registration Statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the Registration Statement;
(iii)     To include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement or any material change to such information in the Registration Statement;
provided, however,
that paragraphs
(a)(1)(i) and (a)(1)(ii) do not apply if the information required to be included in a post-effective amendment by those paragraphs
is contained in reports filed with or furnished to the Securities and Exchange Commission by the Registrant pursuant to Section 13
or Section 15(d) of the Securities Exchange Act of 1934 that are incorporated by reference in the Registration Statement.
(2)       
That, for the purpose of determining any liability under the Securities Act of 1933, each such post-effective amendment shall be
deemed to be a new registration statement relating to the securities offered herein, and the offering of such securities at that
time shall be deemed to be the initial bona fide offering thereof.
(3)       
To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at
the termination of the offering.
(4)       
That, for the purpose of determining liability of the registrant under the Securities Act of 1933 to any purchaser in the initial
distribution of the securities, in a primary offering of securities of the Registrant pursuant to this Registration Statement,
regardless of the underwriting method used to sell the securities to the purchaser, if the securities are offered or sold to such
purchaser by means of any of the following communications, the Registrant will be a seller to the purchaser and will be considered
to offer or sell such securities to such purchaser:
1
(i)     Any preliminary prospectus or prospectus of the Registrant relating to the offering required to be filed pursuant to Rule 424 under the Securities Act of 1933;
(ii)     Any free writing prospectus relating to the offering prepared by or on behalf of the Registrant or used or referred to by the Registrant;
(iii)     The portion of any other free writing prospectus relating to the offering containing material information about the Registrant or its securities provided by or on behalf of the Registrant; and
(iv)     Any other communication that is an offer in the offering made by the Registrant to the purchaser.
(b)       
The undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act of 1933,
each filing of the Registrant's annual report pursuant to Section 13(a) or Section 15(d) of the Securities Exchange Act of
1934 that is incorporated by reference in this Registration Statement shall be deemed to be a new registration statement relating
to the securities offered herein, and the offering of such securities at that time shall be deemed to be the initial bona fide
offering thereof.
(c)       
Insofar as indemnification for liabilities arising under the Securities Act of 1933 may be permitted to directors, officers and
controlling persons of the Registrant pursuant to the foregoing provisions, or otherwise, the Registrant has been advised that
in the opinion of the Commission such indemnification is against public policy as expressed in the Act and is, therefore, unenforceable.
In the event that a claim for indemnification against such liabilities (other than the payment by the Registrant of expenses incurred
or paid by a director, officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding)
is asserted by such director, officer or controlling person in connection with the securities being registered, the Registrant
will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate
jurisdiction the question whether such indemnification by it is against public policy as expressed in the Act and will be governed
by the final adjudication of such issue.
2
SIGNATURES
Pursuant
to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets
all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf
by the undersigned, thereunto duly authorized, in the City of Fort Lauderdale, State of Florida, on this 8th day of March, 2012.
MAKO Surgical Corp.
By:
/s/ Maurice R. Ferré, M.D.
Maurice R. Ferré, M.D.
President and Chief Executive Officer and
Chairman of the Board
Each person whose signature appears below constitutes and appoints
Maurice R. Ferré and Fritz L. LaPorte, and each of them individually, his true and lawful attorney-in-fact and agent, with
full powers of substitution and resubstitution, for him and in his name, place and stead, in any and all capacities, to sign any
and all amendments (including post-effective amendments) to this Registration Statement, and to file the same, with all exhibits
thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact
and agents, and each of them individually, full power and authority to do and perform each and every act and thing requisite and
necessary to be done in and about the premises, as fully to all intents and purposes as he or she might or could do in person,
hereby ratifying and confirming all that said attorneys-in-fact and agents, or any of them individually, or their substitute or
substitutes, may lawfully do or cause to be done by virtue hereof.
Pursuant to the requirements of the Securities Act, this Registration
Statement has been signed below by the following persons in the capacities indicated below on March 8, 2012.
Signature
Title
/s/ Maurice R. Ferré, M.D.
Chief Executive Officer, President and Chairman of the Board
(Principal Executive Officer)
Maurice R. Ferré, M.D.
/s/ Fritz L. LaPorte
Senior Vice President of Finance and Administration, Chief Financial Officer and Treasurer (Principal Financial Officer and Principal Accounting Officer)
Fritz L. LaPorte
/s/ S. Morry Blumenfeld, Ph.D.
Director
S. Morry Blumenfeld, Ph.D.
/s/ Christopher C. Dewey
Director
Christopher C. Dewey
/s/ Charles W. Federico
Director
Charles W. Federico
/s/ John G. Freund, M.D.
Director
John G. Freund, M.D.
/s/ Frederic H. Moll, M.D.
Director
Frederic H. Moll, M.D.
/s/ William D. Pruitt
Director
William D. Pruitt
/s/ Richard R. Pettingill
Director
Richard R. Pettingill
/s/ John J. Savarese, M.D.
Director
John J. Savarese, M.D.
S-1
EXHIBIT INDEX
Exhibit
Number
Document Description
4
MAKO Surgical Corp. 2008 Omnibus Incentive Plan (1)
5
Opinion of Foley & Lardner LLP (including consent of counsel) (2)
23.1
Consent of Foley & Lardner LLP (filed as part of Exhibit (5)) (2)
23.2
Consent of Ernst & Young LLP, Independent Registered Public Accounting Firm (2)
24
Powers of Attorney (included on the signature page hereto)
Documents incorporated by reference to filings made by MAKO Surgical
Corp. under the Securities Exchange Act of 1934, as amended, are under Securities and Exchange Commission ("SEC") File
No. 001-33966.
____________________________________
(1)
Incorporated by reference to the Registrant's Registration Statement on Form S-1, as amended, filed with the SEC on September 19, 2007 (Registration No. 333-146162).
(2)
Filed herewith.