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<P ALIGN=CENTER><FONT SIZE=2>As filed with the Securities and Exchange
Commission on August 10, 2011</FONT></P>

<P ALIGN=RIGHT><FONT SIZE=2>Registration No. 333-_______ </FONT></P>

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<P ALIGN=CENTER><FONT SIZE=2><B>UNITED STATES <BR>
SECURITIES AND EXCHANGE COMMISSION <BR>
</B>Washington, D.C. 20549</FONT></P>




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<DIV ALIGN=CENTER><FONT SIZE=2><B>FORM S-8<BR>
</B><B>REGISTRATION
STATEMENT UNDER THE <BR>
SECURITIES ACT OF 1933 </B></FONT></DIV>
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<div ALIGN=CENTER><FONT SIZE=2><B>ST. JUDE MEDICAL, INC.<BR>
</B>(Exact name of registrant as specified in its charter)</FONT></div>

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 <P ALIGN=CENTER><FONT SIZE=2><B>Minnesota</B></FONT></P>
 </TD>
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 <P><FONT SIZE=1>&nbsp;</FONT></P>
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 <P ALIGN=CENTER><FONT SIZE=2><B>41-1276891</B></FONT></P>
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 <P><FONT SIZE=1>&nbsp;</FONT></P>
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 <P><FONT SIZE=1>&nbsp;</FONT></P>
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 <P ALIGN=CENTER><FONT SIZE=2>(State or other jurisdiction</FONT></P>
 </TD>
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 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
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 <P ALIGN=CENTER><FONT SIZE=2>(I.R.S. Employer</FONT></P>
 </TD>
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 <P><FONT SIZE=1>&nbsp;</FONT></P>
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 <P><FONT SIZE=1>&nbsp;</FONT></P>
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 <P ALIGN=CENTER><FONT SIZE=2>of incorporation or organization)</FONT></P>
 </TD>
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 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
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 <P ALIGN=CENTER><FONT SIZE=2>Identification No.)</FONT></P>
 </TD>
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 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
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<BR>

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 <P ALIGN=CENTER><FONT SIZE=2><B>One St. Jude Medical Drive</B></FONT></P>
 </TD>
 </TR>
 <TR>
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 <P ALIGN=CENTER><FONT SIZE=2><B>St. Paul, Minnesota 55117</B></FONT></P>
 </TD>
 </TR>
 <TR>
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 <P ALIGN=CENTER><FONT SIZE=2>(Address of principal executive offices, including zip code)</FONT></P>
 </TD>
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<P ALIGN=CENTER><FONT SIZE=2><B>ST. JUDE MEDICAL, INC. 2007 STOCK INCENTIVE PLAN, AS
AMENDED AND RESTATED (2011)<BR>
</B>(Full title of the plan)</FONT></P>

<P ALIGN=CENTER><FONT SIZE=2><B>Pamela S. Krop<BR>
Vice President, General Counsel and Corporate Secretary <BR>
St. Jude Medical, Inc. <BR>
One St. Jude Medical Drive <BR>
St. Paul, Minnesota 55117 <BR>
(651) 756-2000 <BR>
</B>(Name, address and telephone number, including area code, of agent for service)</FONT></P>

<P><FONT SIZE=2>Indicate by check mark
whether the registrant is a large accelerated filer, an accelerated filer, a
non-accelerated filer, or a smaller reporting company. See the definitions of
&#147;large accelerated filer,&#148; &#147;accelerated filer&#148; and &#147;smaller reporting company&#148;
in Rule 12b-2 of the Exchange Act. </FONT></P>

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 <P><FONT SIZE=2>Large accelerated filer <FONT  FACE=WINGDINGS>x</FONT></FONT></P>
 </TD>
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 <P><FONT SIZE=2>Accelerated filer <FONT  FACE=WINGDINGS>o</FONT></FONT></P>
 </TD>
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 <P><FONT SIZE=1>&nbsp;</FONT></P>
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 <P><FONT SIZE=1>&nbsp;</FONT></P>
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 <P><FONT SIZE=2>Non-accelerated filer <FONT  FACE=WINGDINGS>o</FONT></FONT></P>
 </TD>
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 <P><FONT SIZE=2>Smaller reporting company <FONT  FACE=WINGDINGS>o</FONT></FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>(Do not check if a smaller
 reporting company)</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
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</TABLE>

<BR>

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 <TD COLSPAN=5 VALIGN=TOP STYLE="BORDER-BOTTOM:DOUBLE BLACK 3PX">
 <P ALIGN=CENTER><FONT SIZE=2><B>CALCULATION OF REGISTRATION FEE</B></FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=BOTTOM STYLE="BORDER-BOTTOM:SOLID BLACK 1PX;">
 <P><FONT SIZE=2><B>Title of securities to be registered</B></FONT></P>


 </TD>
 <TD VALIGN=BOTTOM STYLE="BORDER-BOTTOM:SOLID BLACK 1PX;BORDER-LEFT:SOLID BLACK 1PX">
 <P ALIGN=CENTER><FONT SIZE=2><B>Amount<BR>to be<BR>registered(1)(2)</B></FONT></P>


 </TD>
 <TD VALIGN=BOTTOM STYLE="BORDER-BOTTOM:SOLID BLACK 1PX;BORDER-LEFT:SOLID BLACK 1PX">
 <P ALIGN=CENTER><FONT SIZE=2><B>Proposed<BR>maximum<BR>offering price per<BR>share(3)</B></FONT></P>


 </TD>
 <TD VALIGN=BOTTOM STYLE="BORDER-BOTTOM:SOLID BLACK 1PX;BORDER-LEFT:SOLID BLACK 1PX">
 <P ALIGN=CENTER><FONT SIZE=2><B>Proposed maximum <BR>
 aggregate offering<BR>price(3)</B></FONT></P>


 </TD>
 <TD VALIGN=BOTTOM STYLE="BORDER-BOTTOM:SOLID BLACK 1PX;BORDER-LEFT:SOLID BLACK 1PX">
 <P ALIGN=CENTER><FONT SIZE=2><B>Amount of<BR>
 registration fee</B></FONT></P>


 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP STYLE="BORDER-BOTTOM:DOUBLE BLACK 3PX">
 <P><FONT SIZE=2>Common
 Stock, par value $0.10 per share</FONT></P>
 </TD>
 <TD VALIGN=BOTTOM STYLE="BORDER-BOTTOM:DOUBLE BLACK 3PX;BORDER-LEFT:SOLID BLACK 1PX">
 <P ALIGN=CENTER><FONT SIZE=2>20,000,000 Shares</FONT></P>
 </TD>
 <TD VALIGN=BOTTOM STYLE="BORDER-BOTTOM:DOUBLE BLACK 3PX;BORDER-LEFT:SOLID BLACK 1PX">
 <P ALIGN=CENTER><FONT SIZE=2>$42.33</FONT></P>
 </TD>
 <TD VALIGN=BOTTOM STYLE="BORDER-BOTTOM:DOUBLE BLACK 3PX;BORDER-LEFT:SOLID BLACK 1PX">
 <P ALIGN=CENTER><FONT SIZE=2>$846,600,000</FONT></P>
 </TD>
 <TD VALIGN=BOTTOM STYLE="BORDER-BOTTOM:DOUBLE BLACK 3PX;BORDER-LEFT:SOLID BLACK 1PX">
 <P ALIGN=CENTER><FONT SIZE=2>$98,291</FONT></P>
 </TD>
 </TR>
</TABLE>

<BR>

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 <P><FONT SIZE=2>(1)</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Represents
 the shares of common stock of St. Jude Medical, Inc. that may be offered or
 sold pursuant to the St. Jude Medical, Inc. 2007 Stock Incentive Plan, as
 amended and restated (2011). </FONT></P>
 </TD>
 </TR>
  <TR>
 <TD STYLE="vertical-align: top">&nbsp;&nbsp;</TD>
 <TD STYLE="vertical-align: top">&nbsp;</TD></TR>
<TR>
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 <P><FONT SIZE=2>(2)</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Pursuant to
 Rule 416 under the Securities Act of 1933, as amended, this registration
 statement also covers any additional shares of common stock that may be
 offered or issued under the St. Jude Medical, Inc. 2007 Stock Incentive Plan,
 as amended and restated (2011), to prevent dilution resulting from stock
 splits, stock dividends or similar transactions. </FONT></P>
 </TD>
 </TR>
  <TR>
 <TD STYLE="vertical-align: top">&nbsp;&nbsp;</TD>
 <TD STYLE="vertical-align: top">&nbsp;</TD></TR>
<TR>
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 <P><FONT SIZE=2>(3)</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Estimated
 solely for the purpose of calculating the registration fee in accordance with
 Rule 457(h)(1) and (c) under the Securities Act of 1933, as amended. The
 proposed maximum offering price is based on the average of the high and low
 prices of St. Jude Medical, Inc. common stock as reported on the New York
 Stock Exchange on August 8, 2011. </FONT></P>
 </TD>
 </TR>
</TABLE>

<BR>

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<DIV STYLE="font-size: 1pt; border-top: Black 1pt solid; border-bottom: Black 2pt solid; width: 100%">&nbsp;</DIV></DIV>

<BR>
<HR NOSHADE ALIGN=CENTER WIDTH="100%" SIZE=3><P STYLE='PAGE-BREAK-BEFORE: ALWAYS'></P><PAGE>

<P ALIGN=CENTER><FONT SIZE=2><B>PART II</B></FONT></P>

<P ALIGN=CENTER><FONT SIZE=2><B>INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</B></FONT></P>

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 <P><FONT SIZE=2><B>Item 3.</B></FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2><B>Incorporation
 of Documents by Reference. </B></FONT></P>
 </TD>
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</TABLE>

<P STYLE="text-indent: 3%"><FONT SIZE=2>The following documents,
which have been filed with the Securities and Exchange Commission (the &#147;SEC&#148;)
by St. Jude Medical, Inc. (&#147;we,&#148;
&#147;us,&#148; &#147;our&#148; or &#147;St. Jude&#148;), are incorporated by reference in this registration
statement: </FONT></P>

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    <TD STYLE="width: 3%">&nbsp;</TD>
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 <P>&nbsp;</P>
 </TD>
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 <P>&nbsp;</P>
 </TD>
 </TR>
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    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>(a)</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>Our Annual Report on Form
 10-K for the fiscal year ended January 1, 2011; </FONT></P>
 </TD>
 </TR>
 <TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>(b)</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>Our Quarterly Reports on
 Form 10-Q for the fiscal quarters ended April 2, 2011 and July 2, 2011; </FONT></P>
 </TD>
 </TR>
 <TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>(c)</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>Our Current Report on Form
 8-K filed on May 13, 2011; and </FONT></P>
 </TD>
 </TR>
 <TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>(d)</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>The description of our
 common stock contained in any registration statement or report filed by us
 under the Securities Exchange Act of 1934, as amended (the &#147;Exchange Act&#148;),
 including any amendment or report filed for the purpose of updating such
 description. </FONT></P>
 </TD>
 </TR>
</TABLE>

<P STYLE="text-indent: 3%"><FONT SIZE=2>All documents filed by us
pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act subsequent
to the date hereof, and prior to the filing of a post-effective amendment which
indicates that all securities offered hereby have been sold or which
deregisters all securities remaining unsold, shall be deemed to be incorporated
by reference herein and to be a part hereof from the respective dates of filing
of such documents. </FONT></P>

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 <P>&nbsp;</P>
 </TD>
 </TR>
 <TR>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2><B>Item 4.</B></FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2><B>Description
 of Securities. </B></FONT></P>
 </TD>
 </TR>
</TABLE>

<P STYLE="text-indent: 3%"><FONT SIZE=2>Not applicable.</FONT></P>

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 <P>&nbsp;</P>
 </TD>
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 <P>&nbsp;</P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2><B>Item 5.</B></FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2><B>Interests
 of Named Experts and Counsel. </B></FONT></P>
 </TD>
 </TR>
</TABLE>

<P STYLE="text-indent: 3%"><FONT SIZE=2>Not applicable. </FONT></P>

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 <TR STYLE="FONT-SIZE:1PX">
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 </TD>
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 <P>&nbsp;</P>
 </TD>
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 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2><B>Item 6.</B></FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2><B>Indemnification
 of Directors and Officers. </B></FONT></P>
 </TD>
 </TR>
</TABLE>

<P STYLE="text-indent: 3%"><FONT SIZE=2>Section 521 of the Minnesota
Business Corporation Act provides that a company shall, subject to certain
limitations, indemnify officers and directors made or threatened to be made a
party to a proceeding by reason of that officer or director&#146;s former or present
official capacity with the company. As required, we will indemnify that person
against judgments, penalties, fines, settlements and reasonable expenses if the
officer or director: </FONT></P>

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 <TR STYLE="FONT-SIZE:1PX">
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="width: 4%; vertical-align: top">
 <P>&nbsp;</P>
 </TD>
 <TD STYLE="width: 87%; vertical-align: top">
 <P>&nbsp;</P>
 </TD>
 </TR>
 <TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>&#149;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>has not been indemnified by
 another organization; </FONT></P>
 </TD>
 </TR>
<TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
  <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>&#149;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>acted in good faith; </FONT></P>
 </TD>
 </TR>
<TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
  <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>&#149;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>has not received an
 improper personal benefit and Section 255 regarding director conflicts of
 interests, if applicable, has been satisfied; </FONT></P>
 </TD>
 </TR>
<TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
  <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>&#149;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>assuming the case is a
 criminal proceeding, the person had no reasonable cause to believe the
 conduct was unlawful; and </FONT></P>
 </TD>
 </TR>
</TABLE>
<P ALIGN=CENTER><FONT SIZE=2>II-1</FONT></P>

<HR NOSHADE ALIGN=CENTER WIDTH="100%" SIZE=3><P STYLE='PAGE-BREAK-BEFORE: ALWAYS'></P><PAGE>

<BR>

<TABLE BORDER=0 CELLSPACING=0 CELLPADDING=0 WIDTH="100%">
 <TR STYLE="FONT-SIZE:1PX">
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="width: 4%; vertical-align: top">
 <P>&nbsp;</P>
 </TD>
 <TD STYLE="width: 87%; vertical-align: top">
 <P>&nbsp;</P>
 </TD>
 </TR>
 <TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>&#149;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>reasonably believed that
 the conduct was in the best interests of the company or, in the case of an
 officer or director who is or was serving at the request of the company as a
 director, officer, partner, trustee, employee or agent of another
 organization or employee benefit plan, reasonably believed that the conduct
 was not opposed to the best interests of the company. </FONT></P>
 </TD>
 </TR>
</TABLE>

<P STYLE="text-indent: 3%"><FONT SIZE=2>Article XIV of our Articles
of Incorporation, as amended, provides that, to the fullest extent permissible
under the Minnesota Business Corporation Act, our directors shall not be liable
to St. Jude or our shareholders for monetary damages for breach of fiduciary
duty as a director.</FONT></P>

<P STYLE="text-indent: 3%"><FONT SIZE=2>Article VII of our Bylaws, as
amended and restated, provides that we shall indemnify our officers and
directors under such circumstances and to the extent permitted by Section 521
of the Minnesota Business Corporation Act described above. </FONT></P>

<P STYLE="text-indent: 3%"><FONT SIZE=2>We enter into indemnification
agreements with our directors and officers. The indemnification agreements
provide that we shall, subject to certain limitations, indemnify our directors
and officers who are made or threatened to be made a party to a proceeding by
reason of their former or present official capacities with St. Jude. The
circumstances under which we will indemnify our directors or officers against
judgments, penalties, fines, settlements and reasonable expenses pursuant to
these indemnification agreements are the same as those provided in Section 521
of the Minnesota Business Corporation Act described above. </FONT></P>

<P STYLE="text-indent: 3%"><FONT SIZE=2>We maintain directors&#146; and
officers&#146; liability insurance which covers certain liabilities and expenses of
our directors and officers and covers St. Jude for reimbursement of payments to
our directors and officers in respect of such liabilities and expenses. </FONT></P>

<TABLE BORDER=0 CELLSPACING=0 CELLPADDING=0 WIDTH="100%">
 <TR STYLE="FONT-SIZE:1PX">
 <TD WIDTH="8%" VALIGN=TOP>
 <P>&nbsp;</P>
 </TD>
 <TD WIDTH="92%" VALIGN=TOP>
 <P>&nbsp;</P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2><B>Item 7.</B></FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2><B>Exemption
 from Registration Claimed. </B></FONT></P>
 </TD>
 </TR>
</TABLE>

<P STYLE="text-indent: 3%"><FONT SIZE=2>Not applicable. </FONT></P>

<TABLE BORDER=0 CELLSPACING=0 CELLPADDING=0 WIDTH="100%">
 <TR STYLE="FONT-SIZE:1PX">
 <TD WIDTH="8%" VALIGN=TOP>
 <P>&nbsp;</P>
 </TD>
 <TD WIDTH="92%" VALIGN=TOP>
 <P>&nbsp;</P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2><B>Item 8.</B></FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2><B>Exhibits. </B></FONT></P>
 </TD>
 </TR>
</TABLE>

<BR>

<TABLE BORDER=0 CELLSPACING=0 CELLPADDING=0 WIDTH="100%">
 <TR STYLE="FONT-SIZE:1PX">
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="width: 4%; vertical-align: top">
 <P>&nbsp;</P>
 </TD>
 <TD STYLE="width: 87%; vertical-align: top">
 <P>&nbsp;</P>
 </TD>
 </TR>
 <TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>4.1</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>Articles of Incorporation,
 as amended on May 9, 2008 (incorporated by reference to Exhibit 3.1 of St. Jude&#146;s
 Quarterly Report on Form 10-Q for the quarter ended June 28, 2008). </FONT></P>
 </TD>
 </TR>
 <TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top; padding-top:10pt">
 <P><FONT SIZE=2>4.2</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top; padding-top:10pt">
 <P><FONT SIZE=2>Bylaws, as amended and
 restated as of February 25, 2005 (incorporated by reference to Exhibit 3.1 of
 St. Jude&#146;s Current Report on Form 8-K filed on March 2, 2005). </FONT></P>
 </TD>
 </TR>
 <TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top; padding-top:10pt">
 <P><FONT SIZE=2>4.3</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top; padding-top:10pt">
 <P><FONT SIZE=2>St. Jude Medical, Inc. 2007
 Stock Incentive Plan, as amended and restated (2011) (incorporated by
 reference to Exhibit 10.1 of St. Jude&#146;s Current Report on Form 8-K filed on
 May 13, 2011). </FONT></P>
 </TD>
 </TR>
 <TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top; padding-top:10pt">
 <P><FONT SIZE=2>5.1</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top; padding-top:10pt">
 <P><FONT SIZE=2>Opinion of Dorsey &amp;
 Whitney LLP. </FONT></P>
 </TD>
 </TR>
 <TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top; padding-top:10pt">
 <P><FONT SIZE=2>23.1</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top; padding-top:10pt">
 <P><FONT SIZE=2>Consent of Dorsey &amp;
 Whitney LLP (included in Exhibit 5.1). </FONT></P>
 </TD>
 </TR>
 <TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top; padding-top:10pt">
 <P><FONT SIZE=2>23.2</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top; padding-top:10pt">
 <P><FONT SIZE=2>Consent of Ernst &amp;
 Young LLP. </FONT></P>
 </TD>
 </TR>
 <TR>
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="vertical-align: top; padding-top:10pt">
 <P><FONT SIZE=2>24.1</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top; padding-top:10pt">
 <P><FONT SIZE=2>Power of Attorney.</FONT></P>
 </TD>
 </TR>
</TABLE>
<P ALIGN=CENTER><FONT SIZE=2>II-2</FONT></P>

<HR NOSHADE ALIGN=CENTER WIDTH="100%" SIZE=3><P STYLE='PAGE-BREAK-BEFORE: ALWAYS'></P><PAGE>


<BR>

<TABLE BORDER=0 CELLSPACING=0 CELLPADDING=0 WIDTH="100%">
 <TR STYLE="FONT-SIZE:1PX">
 <TD WIDTH="8%" VALIGN=TOP>
 <P>&nbsp;</P>
 </TD>
 <TD WIDTH="92%" VALIGN=TOP>
 <P>&nbsp;</P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2><B>Item 9.</B></FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2><B>Undertakings.</B></FONT></P>
 </TD>
 </TR>
</TABLE>
<BR>

<TABLE BORDER="0" CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%">
 <TR STYLE="FONT-SIZE:1PX">
    <TD STYLE="width: 3%">&nbsp;</TD>
 <TD STYLE="width: 4%; vertical-align: top">
 <P>&nbsp;</P>
 </TD>
 <TD STYLE="width: 87%; vertical-align: top">
 <P>&nbsp;</P>
 </TD>
 </TR>
 <TR>
    <TD>&nbsp;</TD>
 <TD COLSPAN=2 VALIGN=TOP>
 <P><FONT SIZE=2>(a)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The
 undersigned registrant hereby undertakes: </FONT></P>
 </TD>
 </TR>
 <TR>
    <TD>&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
    <TD>&nbsp;</TD>
 <TD COLSPAN=2 VALIGN=TOP>
 <P><FONT SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;To
 file, during any period in which offers or sales are being made, a
 post-effective amendment to this registration statement: </FONT></P>
 </TD>
 </TR>
 <TR>
    <TD>&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
    <TD>&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(i)
 To include any prospectus required by Section 10(a)(3) of the Securities Act
 of 1933, as amended (the &#147;Securities Act&#148;); </FONT></P>
 </TD>
 </TR>
 <TR>
    <TD>&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
    <TD>&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(ii)
 To reflect in the prospectus any facts or events arising after the effective
 date of the registration statement (or the most recent post-effective
 amendment thereof) which, individually or in the aggregate, represent a
 fundamental change in the information set forth in the registration
 statement. Notwithstanding the foregoing, any increase or decrease in volume
 of securities offered (if the total dollar value of securities offered would
 not exceed that which was registered) and any deviation from the low or high
 end of the estimated maximum offering range may be reflected in the form of
 prospectus filed with the SEC pursuant to Rule 424(b) if, in the aggregate,
 the changes in volume and price represent no more than a 20% change in the
 maximum aggregate offering price set forth in the &#147;Calculation of
 Registration Fee&#148; table in the effective registration statement; and </FONT></P>
 </TD>
 </TR>
 <TR>
    <TD>&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
    <TD>&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(iii)
 To include any material information with respect to the plan of distribution
 not previously disclosed in the registration statement or any material change
 to such information in the registration statement; </FONT></P>
 </TD>
 </TR>
 <TR>
    <TD>&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
    <TD>&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=2><I>provided</I>, <I>however,</I>
 that paragraphs (a)(1)(i) and (a)(1)(ii) above do not apply if the
 information required to be included in a post-effective amendment by those
 paragraphs is contained in reports filed with or furnished to the SEC by the
 registrant pursuant to Section 13 or Section 15(d) of the Exchange Act that
 are incorporated by reference in the registration statement. </FONT></P>
 </TD>
 </TR>
 <TR>
    <TD>&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
    <TD>&nbsp;</TD>
 <TD COLSPAN=2 VALIGN=TOP>
 <P><FONT SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;That,
 for the purpose of determining any liability under the Securities Act, each
 such post-effective amendment shall be deemed to be a new registration
 statement relating to the securities offered therein, and the offering of
 such securities at that time shall be deemed to be the initial bona fide
 offering thereof. </FONT></P>
 </TD>
 </TR>
 <TR>
    <TD>&nbsp;</TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD STYLE="vertical-align: top">
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
    <TD>&nbsp;</TD>
 <TD COLSPAN=2 VALIGN=TOP>
 <P><FONT SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;To
 remove from registration by means of a post-effective amendment any of the
 securities being registered which remain unsold at the termination of the
 offering. </FONT></P>
 </TD>
 </TR>
</TABLE>

<P STYLE="text-indent: 3%"><FONT SIZE=2>(b)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The undersigned registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the registrant&#146;s annual report pursuant to Section 13(a) or Section 15(d) of the Exchange Act that is incorporated by reference in the registration statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof. </FONT></P>


<P STYLE="text-indent: 3%"><FONT SIZE=2>(c)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the registrant pursuant to the foregoing provisions, or otherwise, the registrant has been advised that in the opinion of the SEC such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the registrant of expenses incurred or paid by a director, officer or controlling person of the registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered, the registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue. </FONT></P>



<P ALIGN=CENTER><FONT SIZE=2>II-3</FONT></P>

<HR NOSHADE ALIGN=CENTER WIDTH="100%" SIZE=3><P STYLE='PAGE-BREAK-BEFORE: ALWAYS'></P><PAGE>
<P ALIGN=CENTER><FONT SIZE=2><B>SIGNATURES</B></FONT></P>

<P STYLE="text-indent: 3%"><FONT SIZE=2>Pursuant to the requirements
of the Securities Act, the registrant certifies that it has reasonable grounds
to believe that it meets all of the requirements for filing on Form S-8 and has
duly caused this registration statement to be signed on its behalf by the
undersigned, thereunto duly authorized, in the City of St. Paul, State of
Minnesota, on August 10, 2011. </FONT></P>

<TABLE BORDER=0 CELLSPACING=0 CELLPADDING=0 WIDTH="100%">
 <TR STYLE="FONT-SIZE:1PX">
 <TD WIDTH="50%" VALIGN=TOP>
 <P>&nbsp;</P>
 </TD>
 <TD WIDTH="3%" VALIGN=TOP>
 <P>&nbsp;</P>
 </TD>
 <TD WIDTH="47%" VALIGN=TOP>
 <P>&nbsp;</P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD COLSPAN=2 VALIGN=TOP>
 <P><FONT SIZE=2>ST. JUDE MEDICAL, INC.</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>By:&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP STYLE="BORDER-BOTTOM:SOLID BLACK 1PX">
 <P><FONT SIZE=2>/s/ John C. Heinmiller</FONT></P>


 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>John C. Heinmiller</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Executive Vice President
 and Chief Financial Officer</FONT></P>
 </TD>
 </TR>
</TABLE>

<P STYLE="text-indent: 3%"><FONT SIZE=2>Pursuant to the requirements
of the Securities Act, this registration statement has been signed by the
following persons in the capacities indicated on August 10, 2011. </FONT></P>

<TABLE BORDER=0 CELLSPACING=0 CELLPADDING=0 WIDTH="100%">
 <TR STYLE="FONT-SIZE:1PX">
 <TD WIDTH="47%" VALIGN=TOP>
 <P>&nbsp;</P>
 </TD>
 <TD WIDTH="6%" VALIGN=TOP>
 <P>&nbsp;</P>
 </TD>
 <TD WIDTH="47%" VALIGN=TOP>
 <P>&nbsp;</P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2><B>Signature</B></FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2><B>Title</B></FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP STYLE="BORDER-BOTTOM:SOLID BLACK 1PX">
 <P ALIGN=CENTER><FONT SIZE=2>*</FONT></P>


 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>President, Chief Executive
 Officer and Chairman</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Daniel J. Starks</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>(principal executive
 officer)</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP STYLE="BORDER-BOTTOM:SOLID BLACK 1PX">
 <P><FONT SIZE=2>/s/ John C. Heinmiller</FONT></P>


 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Executive Vice President
 and Chief Financial</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>John C. Heinmiller</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Officer</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>(principal financial and
 accounting officer)</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP STYLE="BORDER-BOTTOM:SOLID BLACK 1PX">
 <P ALIGN=CENTER><FONT SIZE=2>*</FONT></P>


 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Director</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>John W. Brown</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP STYLE="BORDER-BOTTOM:SOLID BLACK 1PX">
 <P><FONT SIZE=1>&nbsp;</FONT></P>


 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Director</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Richard R. Devenuti</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP STYLE="BORDER-BOTTOM:SOLID BLACK 1PX">
 <P ALIGN=CENTER><FONT SIZE=2>*</FONT></P>


 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Director</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Stuart M. Essig</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Director</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP STYLE="BORDER-TOP:SOLID BLACK 1PX">
 <P><FONT SIZE=2>Thomas H. Garrett III</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP STYLE="BORDER-BOTTOM:SOLID BLACK 1PX">
 <P ALIGN=CENTER><FONT SIZE=2>*</FONT></P>


 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Director</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Barbara B. Hill</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP STYLE="BORDER-BOTTOM:SOLID BLACK 1PX">
 <P ALIGN=CENTER><FONT SIZE=2>*</FONT></P>


 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Director</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Michael A. Rocca</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP STYLE="BORDER-BOTTOM:SOLID BLACK 1PX">
 <P ALIGN=CENTER><FONT SIZE=2>*</FONT></P>


 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Director</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Wendy L. Yarno</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
</TABLE>

<BR>

<TABLE BORDER=0 CELLSPACING=0 CELLPADDING=0 WIDTH="100%">
 <TR STYLE="FONT-SIZE:1PX">
 <TD WIDTH="5%" VALIGN=TOP>
 <P>&nbsp;</P>
 </TD>
 <TD WIDTH="42%" VALIGN=TOP>
 <P>&nbsp;</P>
 </TD>
 <TD WIDTH="53%" VALIGN=TOP>
 <P>&nbsp;</P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>*By:</FONT></P>
 </TD>
 <TD VALIGN=TOP STYLE="BORDER-BOTTOM:SOLID BLACK 1PX">
 <P><FONT SIZE=2>/s/ Pamela S. Krop</FONT></P>


 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Pamela S. Krop</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Attorney-in-Fact</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
</TABLE>
<P ALIGN=CENTER><FONT SIZE=2>II-4</FONT></P>

<HR NOSHADE ALIGN=CENTER WIDTH="100%" SIZE=3><P STYLE='PAGE-BREAK-BEFORE: ALWAYS'></P><PAGE>
<P ALIGN=CENTER><FONT SIZE=2><B>EXHIBIT INDEX</B></FONT></P>

<TABLE BORDER=0 CELLSPACING=0 CELLPADDING=0 WIDTH="100%">
 <TR STYLE="FONT-SIZE:1PX">
 <TD WIDTH="10%" VALIGN=TOP>
 <P>&nbsp;</P>
 </TD>
 <TD WIDTH="3%" VALIGN=TOP>
 <P>&nbsp;</P>
 </TD>
 <TD WIDTH="87%" VALIGN=TOP>
 <P>&nbsp;</P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP STYLE="BORDER-BOTTOM:SOLID BLACK 1PX">
 <P ALIGN=CENTER><FONT SIZE=2><B>Exhibit <BR>
 Number</B></FONT></P>


 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=BOTTOM STYLE="BORDER-BOTTOM:SOLID BLACK 1PX">
 <P ALIGN=CENTER><FONT SIZE=2><B>Description</B></FONT></P>


 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P ALIGN=CENTER><FONT SIZE=2>4.1</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Articles of Incorporation,
 as amended on May 9, 2008 (incorporated by reference to Exhibit 3.1 of St. Jude&#146;s
 Quarterly Report on Form 10-Q for the quarter ended June 28, 2008).</FONT></P>
 </TD>
 </TR>

 <TR>
 <TD VALIGN=TOP>
 <P ALIGN=CENTER><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P ALIGN=CENTER><FONT SIZE=2>4.2</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Bylaws, as amended and
 restated as of February 25, 2005 (incorporated by reference to Exhibit 3.1 of St. Jude&#146;s
 Current Report on Form 8-K filed on March 2, 2005).</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P ALIGN=CENTER><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P ALIGN=CENTER><FONT SIZE=2>4.3</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>St. Jude Medical, Inc. 2007
 Stock Incentive Plan, as amended and restated (2011) (incorporated by reference
 to Exhibit 10.1 of St. Jude&#146;s Current Report on Form 8-K filed on May 13, 2011).</FONT></P>
 </TD>
 </TR>
  <TR>
 <TD VALIGN=TOP>
 <P ALIGN=CENTER><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P ALIGN=CENTER><FONT SIZE=2>5.1</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Opinion of Dorsey &amp;
 Whitney LLP.</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P ALIGN=CENTER><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P ALIGN=CENTER><FONT SIZE=2>23.1</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Consent of Dorsey &amp;
 Whitney LLP (included in Exhibit 5.1).</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P ALIGN=CENTER><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P ALIGN=CENTER><FONT SIZE=2>23.2</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Consent of Ernst &amp;
 Young LLP.</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P ALIGN=CENTER><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 </TR>
 <TR>
 <TD VALIGN=TOP>
 <P ALIGN=CENTER><FONT SIZE=2>24.1</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=1>&nbsp;</FONT></P>
 </TD>
 <TD VALIGN=TOP>
 <P><FONT SIZE=2>Power of Attorney.</FONT></P>
 </TD>
 </TR>
</TABLE>

<BR>

<HR NOSHADE ALIGN=CENTER WIDTH="100%" SIZE=3>
</BODY>
</HTML>
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{"company-data": {"conformed-name": "ST JUDE MEDICAL INC", "cik": "0000203077", "assigned-sic": "3845", "irs-number": "411276891", "state-of-incorporation": "MN", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-176200", "film-number": "111023663"}, "business-address": {"street1": "ONE ST JUDE MEDICAL DRIVE", "city": "ST PAUL", "state": "MN", "zip": "55117", "phone": "6517562000"}, "mail-address": {"street1": "ONE ST JUDE MEDICAL DRIVE", "city": "ST PAUL", "state": "MN", "zip": "55117"}}
As filed with the Securities and Exchange
Commission on August 10, 2011
Registration No. 333-_______
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-8
REGISTRATION
STATEMENT UNDER THE
SECURITIES ACT OF 1933
ST. JUDE MEDICAL, INC.
(Exact name of registrant as specified in its charter)
Minnesota
41-1276891
(State or other jurisdiction
(I.R.S. Employer
of incorporation or organization)
Identification No.)
One St. Jude Medical Drive
St. Paul, Minnesota 55117
(Address of principal executive offices, including zip code)
ST. JUDE MEDICAL, INC. 2007 STOCK INCENTIVE PLAN, AS
AMENDED AND RESTATED (2011)
(Full title of the plan)
Pamela S. Krop
Vice President, General Counsel and Corporate Secretary
St. Jude Medical, Inc.
One St. Jude Medical Drive
St. Paul, Minnesota 55117
(651) 756-2000
(Name, address and telephone number, including area code, of agent for service)
Indicate by check mark
whether the registrant is a large accelerated filer, an accelerated filer, a
non-accelerated filer, or a smaller reporting company. See the definitions of
"large accelerated filer," "accelerated filer" and "smaller reporting company"
in Rule 12b-2 of the Exchange Act.
Large accelerated filer
x
Accelerated filer
o
Non-accelerated filer
o
Smaller reporting company
o
(Do not check if a smaller
 reporting company)
CALCULATION OF REGISTRATION FEE
Title of securities to be registered
Amount
to be
registered(1)(2)
Proposed
maximum
offering price per
share(3)
Proposed maximum
aggregate offering
price(3)
Amount of
registration fee
Common
 Stock, par value $0.10 per share
20,000,000 Shares
$42.33
$846,600,000
$98,291
(1)
Represents
 the shares of common stock of St. Jude Medical, Inc. that may be offered or
 sold pursuant to the St. Jude Medical, Inc. 2007 Stock Incentive Plan, as
 amended and restated (2011).
(2)
Pursuant to
 Rule 416 under the Securities Act of 1933, as amended, this registration
 statement also covers any additional shares of common stock that may be
 offered or issued under the St. Jude Medical, Inc. 2007 Stock Incentive Plan,
 as amended and restated (2011), to prevent dilution resulting from stock
 splits, stock dividends or similar transactions.
(3)
Estimated
 solely for the purpose of calculating the registration fee in accordance with
 Rule 457(h)(1) and (c) under the Securities Act of 1933, as amended. The
 proposed maximum offering price is based on the average of the high and low
 prices of St. Jude Medical, Inc. common stock as reported on the New York
 Stock Exchange on August 8, 2011.
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 3.
Incorporation
 of Documents by Reference.
The following documents,
which have been filed with the Securities and Exchange Commission (the "SEC")
by St. Jude Medical, Inc. ("we,"
"us," "our" or "St. Jude"), are incorporated by reference in this registration
statement:
(a)
Our Annual Report on Form
 10-K for the fiscal year ended January 1, 2011;
(b)
Our Quarterly Reports on
 Form 10-Q for the fiscal quarters ended April 2, 2011 and July 2, 2011;
(c)
Our Current Report on Form
 8-K filed on May 13, 2011; and
(d)
The description of our
 common stock contained in any registration statement or report filed by us
 under the Securities Exchange Act of 1934, as amended (the "Exchange Act"),
 including any amendment or report filed for the purpose of updating such
 description.
All documents filed by us
pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act subsequent
to the date hereof, and prior to the filing of a post-effective amendment which
indicates that all securities offered hereby have been sold or which
deregisters all securities remaining unsold, shall be deemed to be incorporated
by reference herein and to be a part hereof from the respective dates of filing
of such documents.
Item 4.
Description
 of Securities.
Not applicable.
Item 5.
Interests
 of Named Experts and Counsel.
Not applicable.
Item 6.
Indemnification
 of Directors and Officers.
Section 521 of the Minnesota
Business Corporation Act provides that a company shall, subject to certain
limitations, indemnify officers and directors made or threatened to be made a
party to a proceeding by reason of that officer or director's former or present
official capacity with the company. As required, we will indemnify that person
against judgments, penalties, fines, settlements and reasonable expenses if the
officer or director:
•
has not been indemnified by
 another organization;
•
acted in good faith;
•
has not received an
 improper personal benefit and Section 255 regarding director conflicts of
 interests, if applicable, has been satisfied;
•
assuming the case is a
 criminal proceeding, the person had no reasonable cause to believe the
 conduct was unlawful; and
II-1
•
reasonably believed that
 the conduct was in the best interests of the company or, in the case of an
 officer or director who is or was serving at the request of the company as a
 director, officer, partner, trustee, employee or agent of another
 organization or employee benefit plan, reasonably believed that the conduct
 was not opposed to the best interests of the company.
Article XIV of our Articles
of Incorporation, as amended, provides that, to the fullest extent permissible
under the Minnesota Business Corporation Act, our directors shall not be liable
to St. Jude or our shareholders for monetary damages for breach of fiduciary
duty as a director.
Article VII of our Bylaws, as
amended and restated, provides that we shall indemnify our officers and
directors under such circumstances and to the extent permitted by Section 521
of the Minnesota Business Corporation Act described above.
We enter into indemnification
agreements with our directors and officers. The indemnification agreements
provide that we shall, subject to certain limitations, indemnify our directors
and officers who are made or threatened to be made a party to a proceeding by
reason of their former or present official capacities with St. Jude. The
circumstances under which we will indemnify our directors or officers against
judgments, penalties, fines, settlements and reasonable expenses pursuant to
these indemnification agreements are the same as those provided in Section 521
of the Minnesota Business Corporation Act described above.
We maintain directors' and
officers' liability insurance which covers certain liabilities and expenses of
our directors and officers and covers St. Jude for reimbursement of payments to
our directors and officers in respect of such liabilities and expenses.
Item 7.
Exemption
 from Registration Claimed.
Not applicable.
Item 8.
Exhibits.
4.1
Articles of Incorporation,
 as amended on May 9, 2008 (incorporated by reference to Exhibit 3.1 of St. Jude's
 Quarterly Report on Form 10-Q for the quarter ended June 28, 2008).
4.2
Bylaws, as amended and
 restated as of February 25, 2005 (incorporated by reference to Exhibit 3.1 of
 St. Jude's Current Report on Form 8-K filed on March 2, 2005).
4.3
St. Jude Medical, Inc. 2007
 Stock Incentive Plan, as amended and restated (2011) (incorporated by
 reference to Exhibit 10.1 of St. Jude's Current Report on Form 8-K filed on
 May 13, 2011).
5.1
Opinion of Dorsey &
 Whitney LLP.
23.1
Consent of Dorsey &
 Whitney LLP (included in Exhibit 5.1).
23.2
Consent of Ernst &
 Young LLP.
24.1
Power of Attorney.
II-2
Item 9.
Undertakings.
(a)      The
 undersigned registrant hereby undertakes:
(1)     To
 file, during any period in which offers or sales are being made, a
 post-effective amendment to this registration statement:
(i)
 To include any prospectus required by Section 10(a)(3) of the Securities Act
 of 1933, as amended (the "Securities Act");
(ii)
 To reflect in the prospectus any facts or events arising after the effective
 date of the registration statement (or the most recent post-effective
 amendment thereof) which, individually or in the aggregate, represent a
 fundamental change in the information set forth in the registration
 statement. Notwithstanding the foregoing, any increase or decrease in volume
 of securities offered (if the total dollar value of securities offered would
 not exceed that which was registered) and any deviation from the low or high
 end of the estimated maximum offering range may be reflected in the form of
 prospectus filed with the SEC pursuant to Rule 424(b) if, in the aggregate,
 the changes in volume and price represent no more than a 20% change in the
 maximum aggregate offering price set forth in the "Calculation of
 Registration Fee" table in the effective registration statement; and
(iii)
 To include any material information with respect to the plan of distribution
 not previously disclosed in the registration statement or any material change
 to such information in the registration statement;
provided
,
however,
that paragraphs (a)(1)(i) and (a)(1)(ii) above do not apply if the
 information required to be included in a post-effective amendment by those
 paragraphs is contained in reports filed with or furnished to the SEC by the
 registrant pursuant to Section 13 or Section 15(d) of the Exchange Act that
 are incorporated by reference in the registration statement.
(2)     That,
 for the purpose of determining any liability under the Securities Act, each
 such post-effective amendment shall be deemed to be a new registration
 statement relating to the securities offered therein, and the offering of
 such securities at that time shall be deemed to be the initial bona fide
 offering thereof.
(3)     To
 remove from registration by means of a post-effective amendment any of the
 securities being registered which remain unsold at the termination of the
 offering.
(b)          The undersigned registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the registrant's annual report pursuant to Section 13(a) or Section 15(d) of the Exchange Act that is incorporated by reference in the registration statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.
(c)          Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the registrant pursuant to the foregoing provisions, or otherwise, the registrant has been advised that in the opinion of the SEC such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the registrant of expenses incurred or paid by a director, officer or controlling person of the registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered, the registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.
II-3
SIGNATURES
Pursuant to the requirements
of the Securities Act, the registrant certifies that it has reasonable grounds
to believe that it meets all of the requirements for filing on Form S-8 and has
duly caused this registration statement to be signed on its behalf by the
undersigned, thereunto duly authorized, in the City of St. Paul, State of
Minnesota, on August 10, 2011.
ST. JUDE MEDICAL, INC.
By:
/s/ John C. Heinmiller
John C. Heinmiller
Executive Vice President
 and Chief Financial Officer
Pursuant to the requirements
of the Securities Act, this registration statement has been signed by the
following persons in the capacities indicated on August 10, 2011.
Signature
Title
*
President, Chief Executive
 Officer and Chairman
Daniel J. Starks
(principal executive
 officer)
/s/ John C. Heinmiller
Executive Vice President
 and Chief Financial
John C. Heinmiller
Officer
(principal financial and
 accounting officer)
*
Director
John W. Brown
Director
Richard R. Devenuti
*
Director
Stuart M. Essig
Director
Thomas H. Garrett III
*
Director
Barbara B. Hill
*
Director
Michael A. Rocca
*
Director
Wendy L. Yarno
*By:
/s/ Pamela S. Krop
Pamela S. Krop
Attorney-in-Fact
II-4
EXHIBIT INDEX
Exhibit
Number
Description
4.1
Articles of Incorporation,
 as amended on May 9, 2008 (incorporated by reference to Exhibit 3.1 of St. Jude's
 Quarterly Report on Form 10-Q for the quarter ended June 28, 2008).
4.2
Bylaws, as amended and
 restated as of February 25, 2005 (incorporated by reference to Exhibit 3.1 of St. Jude's
 Current Report on Form 8-K filed on March 2, 2005).
4.3
St. Jude Medical, Inc. 2007
 Stock Incentive Plan, as amended and restated (2011) (incorporated by reference
 to Exhibit 10.1 of St. Jude's Current Report on Form 8-K filed on May 13, 2011).
5.1
Opinion of Dorsey &
 Whitney LLP.
23.1
Consent of Dorsey &
 Whitney LLP (included in Exhibit 5.1).
23.2
Consent of Ernst &
 Young LLP.
24.1
Power of Attorney.