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    <div style="text-align: center; font-weight: bold; font-size: 9pt;">As filed with the Securities and Exchange Commission on May 19, 2021</div>
    <font style="font-size: 9pt;"> </font>
    <div style="text-align: right; font-weight: bold; font-size: 9pt;">Registration No. 333-</div>
    <div>
      <hr style="border: none; border-bottom: 1px solid black; border-top: 4px solid black; height: 10px; color: #ffffff; background-color: #ffffff; text-align: center; margin-left: auto; margin-right: auto;" align="center"></div>
    <div><br>
    </div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 14pt; font-weight: bold; background-color: rgb(255, 255, 255); color: rgb(0, 0, 0); font-style: normal; font-variant: normal; text-transform: none;">SECURITIES AND
      EXCHANGE COMMISSION</div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 12pt; font-weight: bold; background-color: rgb(255, 255, 255); color: rgb(0, 0, 0); font-style: normal; font-variant: normal; text-transform: none;">Washington, D.C.
      20549</div>
    <div><br>
    </div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 18pt; font-weight: bold; background-color: rgb(255, 255, 255); color: rgb(0, 0, 0); font-style: normal; font-variant: normal; text-transform: none;">FORM S-8</div>
    <div><br>
    </div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 12pt; font-weight: bold; background-color: rgb(255, 255, 255); color: rgb(0, 0, 0); font-style: normal; font-variant: normal; text-transform: none;">REGISTRATION
      STATEMENT</div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 12pt; font-weight: bold; background-color: rgb(255, 255, 255); color: rgb(0, 0, 0); font-style: normal; font-variant: normal; text-transform: none;">UNDER</div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 12pt; font-weight: bold; background-color: rgb(255, 255, 255); color: rgb(0, 0, 0); font-style: normal; font-variant: normal; text-transform: none;">THE SECURITIES
      ACT OF 1933</div>
    <div><br>
    </div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 24pt; font-weight: bold; background-color: rgb(255, 255, 255); color: rgb(0, 0, 0); font-style: normal; font-variant: normal; text-transform: none;">INSMED
      INCORPORATED</div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt;">(Exact name of registrant as specified in its charter)</div>
    <div><font style="font-size: 9pt; font-family: 'Times New Roman',Times,serif;"> </font><font style="font-size: 9pt;"><br>
      </font></div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" id="z6d93942e5e0141f48530787aec4372a7" border="0" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 49%; vertical-align: top; font-size: 9pt;">
            <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-weight: bold;">Virginia</div>
          </td>
          <td style="width: 2%; vertical-align: bottom; font-size: 9pt;">&#160;</td>
          <td style="width: 49%; vertical-align: top; font-size: 9pt;">
            <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-weight: bold;">54-1972729</div>
          </td>
        </tr>
        <tr>
          <td style="width: 49%; vertical-align: top; font-size: 9pt;">
            <div style="text-align: center; font-family: 'Times New Roman',Times,serif;">(State or other jurisdiction of incorporation or organization)</div>
          </td>
          <td style="width: 2%; vertical-align: bottom; font-size: 9pt;">&#160;</td>
          <td style="width: 49%; vertical-align: top; font-size: 9pt;">
            <div style="text-align: center; font-family: 'Times New Roman',Times,serif;">(I.R.S. Employer Identification No.)</div>
          </td>
        </tr>

    </table>
    <div style="font-size: 9pt;"><br>
    </div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt; font-weight: bold;">700 US Highway 202/206</div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt; font-weight: bold;">Bridgewater, New Jersey 08807</div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt;">(Address of Principal Executive Offices including zip code)</div>
    <div style="font-size: 9pt;"><br>
    </div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt; font-weight: bold;">Insmed Incorporated 2019 Incentive Plan</div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt; font-weight: bold;">Insmed Incorporated Non-Qualified Stock Option Inducement Awards</div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt;">(Full title of the plans)</div>
    <div style="font-size: 9pt;"><br>
    </div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt; font-weight: bold;">Christine Pellizzari, Esq.</div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt; font-weight: bold;">Insmed Incorporated</div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt; font-weight: bold;">Chief Legal Officer</div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt; font-weight: bold;">700 US Highway 202/206</div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt; font-weight: bold;">Bridgewater, New Jersey 08807</div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt; font-weight: bold;">(908) 977-9900</div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt;">(Name, address, including zip code, and telephone number, including area code, of agent for service)</div>
    <div style="font-size: 9pt;"><br>
    </div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt; font-weight: bold;">Copies of all communications, including all communications sent to the agent for service, should be sent to:</div>
    <div style="font-size: 9pt;"><br>
    </div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt; font-weight: bold;">Michael J. Riella, Esq.</div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt;">Covington &amp; Burling LLP</div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt;">One CityCenter</div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt;">850 Tenth St. NW</div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt;">Washington, DC 20001</div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt;">(202) 662-6000</div>
    <div style="font-size: 9pt;"><br>
    </div>
    <div style="font-family: 'Times New Roman',Times,serif; font-size: 9pt;">Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth
      company. See definitions of &#8220;large accelerated filer,&#8221; &#8220;accelerated filer,&#8221; &#8220;smaller reporting company,&#8221; and &#8220;emerging growth company&#8221; in Rule 12b-2 of the Exchange Act:</div>
    <div style="font-size: 9pt;"><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" id="za665454e92624e748d3a6715bb429ac4" border="0" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 22%; vertical-align: top; font-size: 9pt;">
            <div style="font-family: 'Times New Roman',Times,serif;">Large accelerated filer &#8999;</div>
          </td>
          <td style="width: 2.6%; vertical-align: top; font-size: 9pt;">&#160;</td>
          <td style="width: 22%; vertical-align: top; font-size: 9pt;">
            <div style="font-family: 'Times New Roman',Times,serif;">Accelerated filer &#9744;</div>
          </td>
          <td style="width: 2.6%; vertical-align: top; font-size: 9pt;">&#160;</td>
          <td style="width: 22%; vertical-align: top; font-size: 9pt;">
            <div style="font-family: 'Times New Roman',Times,serif;">Non-accelerated filer &#9744;</div>
          </td>
          <td style="width: 2.6%; vertical-align: top; font-size: 9pt;">&#160;</td>
          <td style="width: 24.57%; vertical-align: top; font-size: 9pt;">
            <div style="font-family: 'Times New Roman',Times,serif;">Smaller reporting company &#9744;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 22%; vertical-align: top; font-size: 9pt;">&#160;</td>
          <td style="width: 2.6%; vertical-align: top; font-size: 9pt;">&#160;</td>
          <td style="width: 22%; vertical-align: top; font-size: 9pt;">&#160;</td>
          <td style="width: 2.6%; vertical-align: top; font-size: 9pt;">&#160;</td>
          <td style="width: 22%; vertical-align: top; font-size: 9pt;">&#160;</td>
          <td style="width: 2.6%; vertical-align: top; font-size: 9pt;">&#160;</td>
          <td style="width: 24.57%; vertical-align: top; font-size: 9pt;">
            <div style="font-family: 'Times New Roman',Times,serif;">Emerging Growth Company &#9744;</div>
          </td>
        </tr>

    </table>
    <div style="font-size: 9pt;"><br>
    </div>
    <div style="font-family: 'Times New Roman',Times,serif; font-size: 9pt;">If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial
      accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. &#9744;</div>
    <div style="font-size: 9pt;"><br>
    </div>
    <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-size: 9pt; font-weight: bold;">CALCULATION OF REGISTRATION FEE</div>
    <div><br>
    </div>
    <table id="z2131967fea4a414fad5908cb5cdda033" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; text-align: left; color: #000000; width: 100%;" cellpadding="0" cellspacing="0">

        <tr>
          <td style="vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0); border-top: 2px double rgb(0, 0, 0); text-align: center;">
            <div style="font-size: 8pt; font-weight: bold;">Title of securities to be registered</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0); border-top: 2px double rgb(0, 0, 0); text-align: center;">&#160;</td>
          <td colspan="2" style="vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0); border-top: 2px double rgb(0, 0, 0); text-align: center;">
            <div style="font-size: 8pt; font-weight: bold;">Amount to be</div>
            <div style="font-size: 8pt; font-weight: bold;">registered (1)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0); border-top: 2px double rgb(0, 0, 0); text-align: center;" nowrap="nowrap">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0); border-top: 2px double rgb(0, 0, 0); text-align: center;">&#160;</td>
          <td colspan="2" style="vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0); border-top: 2px double rgb(0, 0, 0); text-align: center;">
            <div style="font-size: 8pt; font-weight: bold;">Proposed maximum</div>
            <div style="font-size: 8pt; font-weight: bold;">offering price per share</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0); border-top: 2px double rgb(0, 0, 0); text-align: center;" nowrap="nowrap">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0); border-top: 2px double rgb(0, 0, 0); text-align: center;">&#160;</td>
          <td colspan="2" style="vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0); border-top: 2px double rgb(0, 0, 0); text-align: center;">
            <div style="font-size: 8pt; font-weight: bold;">Proposed maximum</div>
            <div style="font-size: 8pt; font-weight: bold;">aggregate offering price</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0); border-top: 2px double rgb(0, 0, 0); text-align: center;" nowrap="nowrap">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0); border-top: 2px double rgb(0, 0, 0); text-align: center;">&#160;</td>
          <td colspan="2" style="vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0); border-top: 2px double rgb(0, 0, 0); text-align: center;">
            <div style="font-size: 8pt; font-weight: bold;">Amount of</div>
            <div style="font-size: 8pt; font-weight: bold;">registration fee</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0); border-top: 2px double rgb(0, 0, 0); text-align: center;" nowrap="nowrap">&#160;</td>
        </tr>
        <tr>
          <td style="vertical-align: middle; width: 52%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="text-indent: -10.1pt; margin-left: 10.1pt; font-family: &#38;quot; font-size: 8pt;">Common Stock, par value $0.01 per share (2)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">2,750,000</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">25.74(3</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">70,785,000.00(3</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">7,722.65</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">&#160;</td>
        </tr>
        <tr>
          <td style="vertical-align: middle; width: 52%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="text-indent: -10.1pt; margin-left: 10.1pt; font-family: &#38;quot; font-size: 8pt;">Common Stock, par value $0.01 per share (4)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">41,450</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">24.99(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">1,035,835.50(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">113.01</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">&#160;</td>
        </tr>
        <tr>
          <td style="vertical-align: middle; width: 52%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="text-indent: -10.1pt; margin-left: 10.1pt; font-family: &#38;quot; font-size: 8pt;">Common Stock, par value $0.01 per share (6)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">66,400</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">29.19(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">1,938,216.00(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">211.46</div>
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          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">&#160;</td>
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        <tr>
          <td style="vertical-align: middle; width: 52%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="text-indent: -10.1pt; margin-left: 10.1pt; font-family: &#38;quot; font-size: 8pt;">Common Stock, par value $0.01 per share (7)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">76,960</div>
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          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
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          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">27.15(5</div>
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          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">2,089,464.00(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">227.97</div>
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          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">&#160;</td>
        </tr>
        <tr>
          <td style="vertical-align: middle; width: 52%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="text-indent: -10.1pt; margin-left: 10.1pt; font-family: &#38;quot; font-size: 8pt;">Common Stock, par value $0.01 per share (8)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">84,520</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">28.17(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">2,380,928.40(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">259.76</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">&#160;</td>
        </tr>
        <tr>
          <td style="vertical-align: middle; width: 52%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="text-indent: -10.1pt; margin-left: 10.1pt; font-family: &#38;quot; font-size: 8pt;">Common Stock, par value $0.01 per share (9)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">42,320</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">33.25(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">1,407,140.00(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">153.52</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">&#160;</td>
        </tr>
        <tr>
          <td style="vertical-align: middle; width: 52%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="text-indent: -10.1pt; margin-left: 10.1pt; font-family: &#38;quot; font-size: 8pt;">Common Stock, par value $0.01 per share (10)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">50,660</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">31.45(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">1,593,257.00(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">173.83</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">&#160;</td>
        </tr>
        <tr>
          <td style="vertical-align: middle; width: 52%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="text-indent: -10.1pt; margin-left: 10.1pt; font-family: &#38;quot; font-size: 8pt;">Common Stock, par value $0.01 per share (11)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">13,560</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">39.14(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">530,738.40(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">57.91</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">&#160;</td>
        </tr>
        <tr>
          <td style="vertical-align: middle; width: 52%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="text-indent: -10.1pt; margin-left: 10.1pt; font-family: &#38;quot; font-size: 8pt;">Common Stock, par value $0.01 per share (12)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">60,020</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">37.44(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">2,247,148.80(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">245.17</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">&#160;</td>
        </tr>
        <tr>
          <td style="vertical-align: middle; width: 52%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="text-indent: -10.1pt; margin-left: 10.1pt; font-family: &#38;quot; font-size: 8pt;">Common Stock, par value $0.01 per share (13)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">27,770</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">37.73(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">1,047,762.10(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">114.32</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">&#160;</td>
        </tr>
        <tr>
          <td style="vertical-align: middle; width: 52%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="text-indent: -10.1pt; margin-left: 10.1pt; font-family: &#38;quot; font-size: 8pt;">Common Stock, par value $0.01 per share (14)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">247,850</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">35.44(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">8,783,804.00(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">958.32</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px; background-color: #CCEEFF;" nowrap="nowrap" valign="bottom">&#160;</td>
        </tr>
        <tr>
          <td style="vertical-align: middle; width: 52%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="text-indent: -10.1pt; margin-left: 10.1pt; font-family: &#38;quot; font-size: 8pt;">Common Stock, par value $0.01 per share (15)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">49,410</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">32.94(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">1,627,565.40(5</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">)</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">&#160;</td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">$</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;" valign="bottom">
            <div style="font-family: &#38;quot; font-size: 8pt;">177.57</div>
          </td>
          <td colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;" nowrap="nowrap" valign="bottom">&#160;</td>
        </tr>

    </table>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="z3c368b09ea44447980b369944ff2b4e1" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 18pt;">
              <div style="text-align: left; text-indent: -13.5pt; margin-left: 13.5pt; font-family: 'Times New Roman',Times,serif; font-size: 8pt;">(1)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="font-size: 8pt; text-align: left;">Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the <font style="font-family: 'Times New Roman',Times,serif;">&#8220;</font>Securities Act<font style="font-family: 'Times New Roman',Times,serif;">&#8221;</font>), this Registration Statement on Form S-8 (the &#8220;Registration Statement&#8221;) also covers such indeterminable number of additional shares of Insmed Incorporated<font style="font-family: 'Times New Roman',Times,serif;">&#8217;</font>s (the <font style="font-family: 'Times New Roman',Times,serif;">&#8220;</font>Registrant<font style="font-family: 'Times New Roman',Times,serif;">&#8221;</font>) common stock, par value $0.01 per share (<font style="font-family: 'Times New Roman',Times,serif;">&#8220;</font>Common Stock<font style="font-family: 'Times New Roman',Times,serif;">&#8221;</font>), as may become issuable under the Registrant<font style="font-family: 'Times New Roman',Times,serif;">&#8217;</font>s 2019 Incentive Plan, as amended (the &#8220;2019 Incentive Plan&#8221;), or any of the Registrant&#8217;s Non-Qualified Stock Option Inducement Awards (as defined below) to prevent dilution in the event of a reorganization,
                reclassification, stock split, dividend or distribution, or any similar transaction.</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <table class="DSPFListTable" id="z64c057dba5fd4cadade2944deae5fca2" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 18pt;">
              <div style="text-align: left; text-indent: -13.5pt; margin-left: 13.5pt; font-family: 'Times New Roman',Times,serif; font-size: 8pt;">(2)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="font-size: 8pt; text-align: left;">Registers additional shares of Common Stock to be issued pursuant to future awards under the 2019 Incentive Plan.</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <table class="DSPFListTable" id="ze5383d5ec9a345ef9e776d15f4d8e6b1" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 18pt;">
              <div style="text-align: left; text-indent: -13.5pt; margin-left: 13.5pt; font-family: 'Times New Roman',Times,serif; font-size: 8pt;">(3)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="font-size: 8pt; text-align: left;">Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(c) and Rule 457(h) under the Securities Act, based upon the average of the high and low prices of the
                Registrant<font style="font-family: 'Times New Roman',Times,serif;">&#8217;</font>s Common Stock on the Nasdaq Global Select Market on May 13, 2021.</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <table class="DSPFListTable" id="z41543fd2e4534e63a02048f378756d9b" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 18pt;">
              <div style="text-align: left; text-indent: -13.5pt; margin-left: 13.5pt; font-family: 'Times New Roman',Times,serif; font-size: 8pt;">(4)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="font-size: 8pt; text-align: left;">Pursuant to the Registrant<font style="font-family: 'Times New Roman',Times,serif;">&#8217;</font>s non-qualified stock option inducement awards to five new employees on June 1, 2020.</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <table class="DSPFListTable" id="zde60b0f90f824530bc8d96ab4ea05e9d" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 18pt;">
              <div style="text-align: left; text-indent: -13.5pt; margin-left: 13.5pt; font-family: 'Times New Roman',Times,serif; font-size: 8pt;">(5)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="font-size: 8pt; text-align: left;">Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h) under the Securities Act, based upon the price at which the relevant stock options may be exercised.</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <table class="DSPFListTable" id="zf172cf79f55b4bc08024c6f420372f4b" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 18pt;">
              <div style="text-align: left; text-indent: -13.5pt; margin-left: 13.5pt; font-family: 'Times New Roman',Times,serif; font-size: 8pt;">(6)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="font-size: 8pt; text-align: left;">Pursuant to the Registrant<font style="font-family: 'Times New Roman',Times,serif;">&#8217;</font>s non-qualified stock option inducement awards to 11 new employees on July 1, 2020.</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <table class="DSPFListTable" id="zec85a334e7ba4c99ba4e0f49cc7dc47e" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 18pt;">
              <div style="text-align: left; text-indent: -13.5pt; margin-left: 13.5pt; font-family: 'Times New Roman',Times,serif; font-size: 8pt;">(7)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="font-size: 8pt; text-align: left;">Pursuant to the Registrant<font style="font-family: 'Times New Roman',Times,serif;">&#8217;</font>s non-qualified stock option inducement awards to 11 new employees on August 3, 2020.</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <table class="DSPFListTable" id="z4f4c9aeb0d194aff8cf701171a098c81" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 18pt;">
              <div style="text-align: left; text-indent: -13.5pt; margin-left: 13.5pt; font-family: 'Times New Roman',Times,serif; font-size: 8pt;">(8)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="font-size: 8pt; text-align: left;">Pursuant to the Registrant<font style="font-family: 'Times New Roman',Times,serif;">&#8217;</font>s non-qualified stock option inducement awards to 12 new employees on September 1, 2020.</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <table class="DSPFListTable" id="z793243040ac04cb0807ad46928086908" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 18pt;">
              <div style="text-align: left; text-indent: -13.5pt; margin-left: 13.5pt; font-family: 'Times New Roman',Times,serif; font-size: 8pt;">(9)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="font-size: 8pt; text-align: left;">Pursuant to the Registrant<font style="font-family: 'Times New Roman',Times,serif;">&#8217;</font>s non-qualified stock option inducement awards to nine new employees on October 1, 2020.</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <table class="DSPFListTable" id="z67ee7f34fd47450293b2a99464ea802f" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 18pt;">
              <div style="text-align: left; text-indent: -13.5pt; margin-left: 13.5pt; font-family: 'Times New Roman',Times,serif; font-size: 8pt;">(10)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="font-size: 8pt; text-align: left;">Pursuant to the Registrant&#8217;s non-qualified stock option inducement awards to 10 new employees on November 2, 2020.</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <table class="DSPFListTable" id="z512fd224047e4dd68a2958446d897a53" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 18pt;">
              <div style="text-align: left; text-indent: -13.5pt; margin-left: 13.5pt; font-family: 'Times New Roman',Times,serif; font-size: 8pt;">(11)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="font-size: 8pt; text-align: left;">Pursuant to the Registrant&#8217;s non-qualified stock option inducement awards to seven new employees on December 1, 2020.</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <table class="DSPFListTable" id="z2477b6c001b64fabbfa1cf8a6b6a21a6" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 18pt;">
              <div style="text-align: left; text-indent: -13.5pt; margin-left: 13.5pt; font-family: 'Times New Roman',Times,serif; font-size: 8pt;">(12)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="font-size: 8pt; text-align: left;">Pursuant to the Registrant&#8217;s non-qualified stock option inducement awards to 14 new employees on February 1, 2021.</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <table class="DSPFListTable" id="z4a722f813c5d460d97124e72bf0efa2d" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 18pt;">
              <div style="text-align: left; text-indent: -13.5pt; margin-left: 13.5pt; font-family: 'Times New Roman',Times,serif; font-size: 8pt;">(13)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="font-size: 8pt; text-align: left;">Pursuant to the Registrant&#8217;s non-qualified stock option inducement awards to seven new employees on March 1, 2021.</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <table class="DSPFListTable" id="z9ce66dc8ce5541889338a092e4988902" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 18pt;">
              <div style="text-align: left; text-indent: -13.5pt; margin-left: 13.5pt; font-family: 'Times New Roman',Times,serif; font-size: 8pt;">(14)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="font-size: 8pt; text-align: left;">Pursuant to the Registrant&#8217;s non-qualified stock option inducement awards to eight new employees on April 1, 2021.</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <table class="DSPFListTable" id="z3aa79105028644a4bce05fc45246866e" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 18pt;">
              <div style="text-align: left; text-indent: -13.5pt; margin-left: 13.5pt; font-family: 'Times New Roman',Times,serif; font-size: 8pt;">(15)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="font-size: 8pt; text-align: left;">Pursuant to the Registrant&#8217;s non-qualified stock option inducement awards to nine new employees on May 3, 2021 (together with the Registrant&#8217;s non-qualified stock option inducement awards
                described in footnotes (4), (6), (7), (8), (9), (10), (11), (12), (13) and (14), the &#8220;Non-Qualified Stock Option Inducement Awards&#8221;).</div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div>
      <hr style="border: none; border-bottom: 4px solid black; border-top: 1px solid black; height: 10px; color: #ffffff; background-color: #ffffff; text-align: center; margin-left: auto; margin-right: auto;" align="center"></div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
      <div style="page-break-after:always;" id="DSPFPageBreak">
        <hr style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;" noshade="noshade"></div>
    </div>
    <div style="margin-bottom: 8pt;"><br>
    </div>
    <div style="text-align: center; font-weight: bold;">PART I</div>
    <div><br>
    </div>
    <div style="text-align: center; font-weight: bold;">INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS</div>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="z597ec28337ce4a91ac87fbbb3784002f" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 45pt;">
              <div style="text-align: left;"><font style="font-weight: bold;">Item 1.</font></div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;"><font style="font-weight: bold;">Plan Information.</font></div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">Not required to be filed as part of this Registration Statement pursuant to the Note to Part I of Form S-8.</div>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="ze35b323ced6b4aa7a350b3a0e9b2f31c" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 45pt;">
              <div style="text-align: left;"><font style="font-weight: bold;">Item 2.</font></div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;"><font style="font-weight: bold;">Registrant Information and Employee Plan Annual Information.</font></div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">Not required to be filed as part of this Registration Statement pursuant to the Note to Part I of Form S-8.</div>
    <div><br>
    </div>
    <div style="text-align: center; font-weight: bold;">PART II</div>
    <div><br>
    </div>
    <div style="text-align: center; font-weight: bold;">INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</div>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="z2c58bfa8417d425387988c9174e5e6d6" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 45pt;">
              <div style="text-align: left;"><font style="font-weight: bold;">Item 3.</font></div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;"><font style="font-weight: bold;">Incorporation of Documents by Reference.</font></div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">The following documents, which have previously been filed by the Registrant with the Securities and Exchange Commission (the &#8220;Commission&#8221;), are incorporated by reference herein and shall be deemed to be a part hereof:</div>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="z329bf131d4e64dbd929df662fd96b7f9" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="width: 36pt;">
              <div><br>
              </div>
            </td>
            <td style="vertical-align: top; width: 27pt;">
              <div style="text-align: left;">(1)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;">The Registrant&#8217;s Annual Report on Form 10-K for the year ended December 31, 2020, filed with the Commission on February 25, 2021;</div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="z8b57144dadeb4785b0a6dad6841241d0" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="width: 36pt;">&#160;</td>
            <td style="vertical-align: top; width: 27pt;">
              <div style="text-align: left;">(2)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;">The Registrant&#8217;s Quarterly Report on Form 10-Q for the quarter ended March 31, 2021, filed with the Commission on May 6, 2021;</div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="z1c4650413f4b4ff1b02e2973cbb4d768" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="width: 36pt;">&#160;</td>
            <td style="vertical-align: top; width: 27pt;">
              <div style="text-align: left;">(3)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;">The Registrant&#8217;s Current Reports on Form 8-K filed with the Commission on February 25, 2021 (solely with respect to Item 1.01), May 13, 2021 (solely with respect to Item 8.01) and May 13, 2021 (solely with
                respect to Items 1.01 and 2.03); and</div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="z69bced7c491242dc9d39b5696f7d6abd" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="width: 36pt;">&#160;</td>
            <td style="vertical-align: top; width: 27pt;">
              <div style="text-align: left;">(4)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;">Description of the Registrant&#8217;s common stock contained in its registration statement on Form 8-A, dated June 1, 2000, as updated by the Description of Securities Registered Under Section 12 of the Exchange Act,
                filed as Exhibit 4.5 to the Registrant&#8217;s Annual Report on Form 10-K for the year ended December 31, 2020, and including any amendment or report subsequently filed for the purpose of updating such description.</div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">In addition, subsequent to the date of this Registration Statement and prior to the filing of a post-effective amendment hereto that indicates all securities offered hereunder have been sold or deregisters all securities
      then remaining unsold, all reports and other documents filed by the Registrant pursuant to Section 13(a), 13(c), 14 or 15(d) of the Securities Exchange Act of 1934, as amended (the &#8220;Exchange Act&#8221;), shall be deemed to be incorporated by reference
      herein and to be a part hereof from the date of filing of such documents; <font style="font-style: italic;">provided, however</font>, that no information furnished (but not filed) under Item 2.02 or Item 7.01 of any Current Report on Form 8-K shall
      be incorporated by reference except to the extent specified in such Current Report on Form 8-K.</div>
    <div><br>
    </div>
    <div style="text-indent: 38.25pt;">For purposes of this Registration Statement, any statement contained in a document incorporated or deemed to be incorporated herein by reference shall be deemed to be modified or superseded to the extent that a
      statement contained herein or in any subsequently filed document that also is incorporated or is deemed to be incorporated herein by reference modifies or supersedes such statement. Any statement so modified or superseded shall not be deemed, except
      as so modified or superseded, to constitute a part of this Registration Statement.</div>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="z1e398580c1444ee58072fa9b812a6d4c" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 45pt;">
              <div style="text-align: left;"><font style="font-weight: bold;">Item 4.</font></div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;"><font style="font-weight: bold;">Description of Securities.</font></div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">Not applicable.</div>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="z819bf0b38e0a4bea925bb0d52c12364a" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 45pt;">
              <div style="text-align: left;"><font style="font-weight: bold;">Item 5.</font></div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;"><font style="font-weight: bold;">Interests of Named Experts and Counsel.</font></div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">Not applicable.</div>
    <div><br>
    </div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
      <div style="page-break-after:always;" id="DSPFPageBreak">
        <hr style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;" noshade="noshade"></div>
    </div>
    <div style="margin-bottom: 8pt;"><br>
    </div>
    <div>
      <table class="DSPFListTable" id="zfc08930c95a541a9932e027982017099" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 45pt;">
              <div style="text-align: left;"><font style="font-weight: bold;">Item 6.</font></div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;"><font style="font-weight: bold;">Indemnification of Directors and Officers.</font></div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">The Virginia Stock Corporation Act (the &#8220;VSCA&#8221;) permits, and the Registrant&#8217;s Articles of Incorporation require, indemnification of the Registrant&#8217;s directors and officers in a variety of circumstances, which may include
      indemnification for liabilities under the Securities Act. Under the VSCA, a Virginia corporation is generally authorized to indemnify its directors and officers in civil or criminal actions if they acted in good faith and believed their conduct to be
      in the best interests of the corporation and, in the case of criminal actions, had no reasonable cause to believe that the conduct was unlawful, or if they engaged in conduct for which broader indemnification has been made permissible or obligatory
      by the Registrant. The VSCA requires such indemnification, unless limited by a corporation&#8217;s articles of incorporation, when a director or officer entirely prevails in the defense of any proceeding to which he or she was a party because he or she is
      or was a director or officer of the corporation. The VSCA provides that a corporation may make any other or further indemnity (including indemnity with respect to a proceeding by or in the right of the corporation), and may make additional provision
      for advances and reimbursement of expenses, if authorized by its articles of incorporation or shareholder-adopted bylaw or resolution, except an indemnity against willful misconduct or a knowing violation of the criminal law. The Registrant&#8217;s
      Articles of Incorporation require indemnification of directors and officers with respect to certain liabilities, expenses and other amounts imposed upon them because of having been a director or officer, except in the case of willful misconduct or a
      knowing violation of criminal law.</div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">The VSCA establishes a statutory limit on liability of directors and officers of a corporation for damages assessed against them in a suit brought by or in the right of the corporation or brought by or on behalf of the
      corporation&#8217;s shareholders and authorizes a corporation to specify a lower monetary limit on liability (including the elimination of liability for monetary damages) in the corporation&#8217;s articles of incorporation or shareholder-approved bylaws;
      however, the liability of a director or officer shall not be limited if such director or officer engaged in willful misconduct or a knowing violation of the criminal law or of any federal or state securities law, including, without limitation, any
      unlawful insider trading or manipulation of the market for any security. As permitted by the VSCA, the Registrant&#8217;s Articles of Incorporation provide that no director or officer of the Registrant shall be liable to the Registrant or the Registrant&#8217;s
      shareholders for monetary damages with respect to any transaction, occurrence or course of conduct, except for liability resulting from such person&#8217;s having engaged in willful misconduct or a knowing violation of the criminal law or any federal or
      state securities law.</div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">Certain directors and officers have been granted contractual indemnification rights under separate indemnification agreements with the Registrant, pursuant to which they will be entitled to indemnification from the
      Registrant under certain circumstances. Additionally, the employment agreements the Registrant has entered into with its executive officers provide for indemnification to the fullest extent permitted by law from and against any and all claims,
      damages, expenses (including attorneys&#8217; fees), judgments, penalties, fines, settlements, and all other liabilities incurred or paid by the executive officer in connection with the investigation, defense, prosecution, settlement or appeal of any
      threatened, pending or completed action, suit or proceeding, whether civil, criminal, administrative or investigative in nature, and to which the executive officer was or is a party or is threatened to be made a party by reason of the fact that he or
      she is or was an officer, employee or agent of the Registrant, or by reason of anything done or not done by him or her in any such capacity or capacities, provided that such executive officer acted in good faith, in a manner that was not grossly
      negligent or that constituted willful misconduct and in a manner he or she reasonably believed to be in or not opposed to the Registrant&#8217;s best interests, and, with respect to any criminal action or proceeding, had no reasonable cause to believe his
      or her conduct was unlawful. The Registrant also carries insurance on behalf of directors, officers, employees or agents that may cover liabilities under the Securities Act.</div>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="z7bf91d22c8db4972a8f36bc32daefb97" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 45pt;">
              <div style="text-align: left; text-indent: 2.25pt;"><font style="font-weight: bold;">Item 7.</font></div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left; text-indent: 2.25pt;"><font style="font-weight: bold;">Exemption From Registration Claimed.</font></div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">Not applicable.</div>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="ze92b7c3b4b384a39932b2ea9d8662a13" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 45pt;">
              <div style="text-align: left;"><font style="font-weight: bold;">Item 8.</font></div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;"><font style="font-weight: bold;">Exhibits.</font></div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">A list of exhibits included in this Registration Statement is set forth on the Exhibit Index and is incorporated herein by reference.</div>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="z21991a19e9434ae797e66f09e11c3ce7" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 45pt;">
              <div style="text-align: left;"><font style="font-weight: bold;">Item 9.</font></div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left; text-indent: -54pt; margin-left: 54pt;"><font style="font-weight: bold;">Undertakings.</font></div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="zb59eaae020214e528bc0b8d00b9d3e46" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 45pt;">
              <div style="text-align: left;">(a)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;">The undersigned Registrant hereby undertakes:</div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="z7dac5b06faa44b0ab32ac87cf46b02a9" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="width: 45pt;">&#160;</td>
            <td style="vertical-align: top; width: 27pt;">
              <div style="text-align: left;">(1)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;">To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:</div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="z822582a95bd84c9f859eb8785af8c9f8" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="width: 72pt;">&#160;</td>
            <td style="vertical-align: top; width: 27pt;">
              <div style="text-align: left;">(i)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;">To include any prospectus required by Section 10(a)(3) of the Securities Act;</div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
      <div style="page-break-after:always;" id="DSPFPageBreak">
        <hr style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;" noshade="noshade"></div>
    </div>
    <div style="margin-bottom: 8pt;"><br>
    </div>
    <div>
      <table class="DSPFListTable" id="z2cc02b05b59d4f4a809cf8c7a94bd037" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="width: 72pt;">&#160;</td>
            <td style="vertical-align: top; width: 27pt;">
              <div style="text-align: left;">(ii)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;">To reflect in the prospectus any facts or events arising after the effective date of the Registration Statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate,
                represent a fundamental change in the information set forth in the Registration Statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities offered would not
                exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the
                changes in volume and price represent no more than 20 percent change in the maximum aggregate offering price set forth in the &#8220;Calculation of Registration Fee&#8221; table in the effective registration statement; and</div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="z8730b8aba7db475392d203f73e0d8691" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="width: 72pt;">&#160;</td>
            <td style="vertical-align: top; width: 27pt;">
              <div style="text-align: left;">(iii)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;">To include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement or any material change to such information in the Registration Statement;</div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div style="margin: 0px 0px 0px 45pt;"><font style="font-style: italic;">provided, however</font>, that paragraphs (a)(1)(i) and (a)(1)(ii) do not apply if the information required to be included in a post-effective amendment by those paragraphs is
      contained in reports filed with or furnished to the Commission by the Registrant pursuant to Section 13 or Section 15(d) of the Exchange Act that are incorporated by reference in the Registration Statement;</div>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="z9a0fcd86816f46b5bbfc2d547f91443e" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="width: 45pt;">&#160;</td>
            <td style="vertical-align: top; width: 27pt;">
              <div style="text-align: left;">(2)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;">That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered therein, and
                the offering of such securities at that time shall be deemed to be the initial <font style="font-style: italic;">bona fide</font> offering thereof; and</div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="zaba24f8fb4a6451a9037ab875901ef87" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="width: 45pt;">&#160;</td>
            <td style="vertical-align: top; width: 27pt;">
              <div style="text-align: left;">(3)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;">To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.</div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="ze73d798e94e545b2868e15780473c736" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 45pt;">
              <div style="text-align: left;">(b)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;">The undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the Registrant&#8217;s annual report pursuant to Section 13(a) or Section 15(d) of
                the Exchange Act (and, where applicable, each filing of an employee benefit plan&#8217;s annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in the Registration Statement shall be deemed to be a new
                registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial <font style="font-style: italic;">bona fide</font> offering thereof.</div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div>
      <table class="DSPFListTable" id="zc948f3559f584935a9d158e8f21a7ea7" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 45pt;">
              <div style="text-align: left;">(c)</div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;">Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the Registrant pursuant to the foregoing provisions, or otherwise,
                the Registrant has been advised that in the opinion of the Commission such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification against
                such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such
                director, officer or controlling person in connection with the securities being registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate
                jurisdiction the question whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.</div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
      <div style="page-break-after:always;" id="DSPFPageBreak">
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    </div>
    <div style="margin-bottom: 8pt;"><br>
    </div>
    <div style="text-align: center; font-weight: bold;">EXHIBIT INDEX</div>
    <div><br>
    </div>
    <div> <br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" id="z1dbcd2f9cae14990a0c5ba9248e03768" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 10.03%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="font-weight: bold;">Exhibit No.</div>
          </td>
          <td style="width: 3%; vertical-align: bottom;">&#160;</td>
          <td style="width: 86.97%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0); text-align: center;">
            <div style="font-weight: bold;">Exhibit Description</div>
          </td>
        </tr>
        <tr>
          <td style="width: 10.03%; vertical-align: top;">
            <div><a href="https://www.sec.gov/Archives/edgar/data/1104506/000110450619000020/insm20190630ex101.htm">4.1</a></div>
          </td>
          <td style="width: 3%; vertical-align: bottom;">&#160;</td>
          <td style="width: 86.97%; vertical-align: top;">
            <div>Insmed Incorporated 2019 Incentive Plan (incorporated by reference from Exhibit 10.1 to Insmed Incorporated&#8217;s Quarterly Report on Form 10-Q, filed on August 1, 2019).</div>
          </td>
        </tr>
        <tr>
          <td style="width: 10.03%; vertical-align: top;">&#160;</td>
          <td style="width: 3%; vertical-align: bottom;">&#160;</td>
          <td style="width: 86.97%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 10.03%; vertical-align: top;">
            <div><a href="https://www.sec.gov/Archives/edgar/data/1104506/000104746920001933/a2241179zdef14a.htm">4.2</a></div>
          </td>
          <td style="width: 3%; vertical-align: bottom;">&#160;</td>
          <td style="width: 86.97%; vertical-align: top;">
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          <td style="width: 10.03%; vertical-align: top;">&#160;</td>
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          <td style="width: 10.03%; vertical-align: top;">&#160;</td>
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          <td style="width: 10.03%; vertical-align: top;">&#160;</td>
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    <div style="text-indent: 36pt;">Pursuant to the requirements of the Securities Act, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration
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          <td style="width: 49.94%; vertical-align: top;">&#160;</td>
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    <div style="text-indent: 36pt;">KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Christine Pellizzari his or her true and lawful attorney with power of substitution and resubstitution to sign
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
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          <td style="width: 28%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
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            <div>Sara Bonstein</div>
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
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            <div>Director</div>
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          <td style="width: 18%; vertical-align: top;">
            <div>May 19, 2021</div>
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          <td style="width: 28%; vertical-align: top;">
            <div>Alfred F. Altomari</div>
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
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          <td style="width: 28%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
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          <td style="width: 28%; vertical-align: top; border-bottom: #000000 2px solid;">
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">
            <div>Director</div>
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">
            <div>May 19, 2021</div>
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          <td style="width: 28%; vertical-align: top;">
            <div>Elizabeth McKee Anderson</div>
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
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          <td style="width: 28%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
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          <td style="width: 28%; vertical-align: top; border-bottom: #000000 2px solid;">
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">
            <div>Director</div>
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">
            <div>May 19, 2021</div>
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          <td style="width: 28%; vertical-align: top;">
            <div>David R. Brennan</div>
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
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          <td style="width: 28%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
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          <td style="width: 28%; vertical-align: top; border-bottom: #000000 2px solid;">
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
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            <div>Director</div>
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">
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          <td style="width: 28%; vertical-align: top;">
            <div>Clarissa Desjardins, Ph.D.</div>
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
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          <td style="width: 28%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
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          <td style="width: 28%; vertical-align: top; border-bottom: #000000 2px solid;">
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">
            <div>Director</div>
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">
            <div>May 19, 2021</div>
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          <td style="width: 28%; vertical-align: top;">
            <div>Steinar J. Engelsen, M.D.</div>
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
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          <td style="width: 28%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
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          <td style="width: 28%; vertical-align: top; border-bottom: #000000 2px solid;">
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">
            <div>Director</div>
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
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          <td style="width: 28%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
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          <td style="width: 28%; vertical-align: top; border-bottom: #000000 2px solid;">
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">
            <div>Director</div>
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">
            <div>May 19, 2021</div>
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          <td style="width: 28%; vertical-align: top;">
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
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          <td style="width: 28%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
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          <td style="width: 28%; vertical-align: top; border-bottom: #000000 2px solid;">
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">
            <div>Director</div>
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">
            <div>May 19, 2021</div>
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          <td style="width: 28%; vertical-align: top;">
            <div>Carol A. Schafer</div>
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
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          <td style="width: 28%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
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            <div style="text-align: center; font-variant: small-caps;">*</div>
          </td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">
            <div>Director</div>
          </td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">
            <div>May 19, 2021</div>
          </td>
        </tr>
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          <td style="width: 28%; vertical-align: top;">
            <div>Melvin Sharoky, M.D.</div>
          </td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
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            <div>* By:</div>
          </td>
          <td style="width: 24%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
            <div>/s/ Christine Pellizzari</div>
          </td>
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            <div>Christine Pellizzari</div>
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            <div style="font-style: italic;">Attorney-in-Fact</div>
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{"company-data": {"conformed-name": "INSMED Inc", "cik": "0001104506", "assigned-sic": "2834", "irs-number": "541972729", "state-of-incorporation": "VA", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-256307", "film-number": "21941427"}, "business-address": {"street1": "700 US HIGHWAY 202/206", "city": "BRIDGEWATER", "state": "NJ", "zip": "08807", "phone": "908-977-9900"}, "mail-address": {"street1": "700 US HIGHWAY 202/206", "city": "BRIDGEWATER", "state": "NJ", "zip": "08807"}, "former-company": {"former-conformed-name": "INSMED INC", "date-changed": "20000128"}}
As filed with the Securities and Exchange Commission on May 19, 2021
Registration No. 333-
SECURITIES AND
      EXCHANGE COMMISSION
Washington, D.C.
      20549
FORM S-8
REGISTRATION
      STATEMENT
UNDER
THE SECURITIES
      ACT OF 1933
INSMED
      INCORPORATED
(Exact name of registrant as specified in its charter)
Virginia
54-1972729
(State or other jurisdiction of incorporation or organization)
(I.R.S. Employer Identification No.)
700 US Highway 202/206
Bridgewater, New Jersey 08807
(Address of Principal Executive Offices including zip code)
Insmed Incorporated 2019 Incentive Plan
Insmed Incorporated Non-Qualified Stock Option Inducement Awards
(Full title of the plans)
Christine Pellizzari, Esq.
Insmed Incorporated
Chief Legal Officer
700 US Highway 202/206
Bridgewater, New Jersey 08807
(908) 977-9900
(Name, address, including zip code, and telephone number, including area code, of agent for service)
Copies of all communications, including all communications sent to the agent for service, should be sent to:
Michael J. Riella, Esq.
Covington & Burling LLP
One CityCenter
850 Tenth St. NW
Washington, DC 20001
(202) 662-6000
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth
      company. See definitions of "large accelerated filer," "accelerated filer," "smaller reporting company," and "emerging growth company" in Rule 12b-2 of the Exchange Act:
Large accelerated filer ⌧
Accelerated filer ☐
Non-accelerated filer ☐
Smaller reporting company ☐
Emerging Growth Company ☐
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial
      accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐
CALCULATION OF REGISTRATION FEE
Title of securities to be registered
Amount to be
registered (1)
Proposed maximum
offering price per share
Proposed maximum
aggregate offering price
Amount of
registration fee
Common Stock, par value $0.01 per share (2)
2,750,000
$
25.74(3
)
$
70,785,000.00(3
)
$
7,722.65
Common Stock, par value $0.01 per share (4)
41,450
$
24.99(5
)
$
1,035,835.50(5
)
$
113.01
Common Stock, par value $0.01 per share (6)
66,400
$
29.19(5
)
$
1,938,216.00(5
)
$
211.46
Common Stock, par value $0.01 per share (7)
76,960
$
27.15(5
)
$
2,089,464.00(5
)
$
227.97
Common Stock, par value $0.01 per share (8)
84,520
$
28.17(5
)
$
2,380,928.40(5
)
$
259.76
Common Stock, par value $0.01 per share (9)
42,320
$
33.25(5
)
$
1,407,140.00(5
)
$
153.52
Common Stock, par value $0.01 per share (10)
50,660
$
31.45(5
)
$
1,593,257.00(5
)
$
173.83
Common Stock, par value $0.01 per share (11)
13,560
$
39.14(5
)
$
530,738.40(5
)
$
57.91
Common Stock, par value $0.01 per share (12)
60,020
$
37.44(5
)
$
2,247,148.80(5
)
$
245.17
Common Stock, par value $0.01 per share (13)
27,770
$
37.73(5
)
$
1,047,762.10(5
)
$
114.32
Common Stock, par value $0.01 per share (14)
247,850
$
35.44(5
)
$
8,783,804.00(5
)
$
958.32
Common Stock, par value $0.01 per share (15)
49,410
$
32.94(5
)
$
1,627,565.40(5
)
$
177.57
(1)
Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the
"
Securities Act
"
), this Registration Statement on Form S-8 (the "Registration Statement") also covers such indeterminable number of additional shares of Insmed Incorporated
'
s (the
"
Registrant
"
) common stock, par value $0.01 per share (
"
Common Stock
"
), as may become issuable under the Registrant
'
s 2019 Incentive Plan, as amended (the "2019 Incentive Plan"), or any of the Registrant's Non-Qualified Stock Option Inducement Awards (as defined below) to prevent dilution in the event of a reorganization,
                reclassification, stock split, dividend or distribution, or any similar transaction.
(2)
Registers additional shares of Common Stock to be issued pursuant to future awards under the 2019 Incentive Plan.
(3)
Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(c) and Rule 457(h) under the Securities Act, based upon the average of the high and low prices of the
                Registrant
'
s Common Stock on the Nasdaq Global Select Market on May 13, 2021.
(4)
Pursuant to the Registrant
'
s non-qualified stock option inducement awards to five new employees on June 1, 2020.
(5)
Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h) under the Securities Act, based upon the price at which the relevant stock options may be exercised.
(6)
Pursuant to the Registrant
'
s non-qualified stock option inducement awards to 11 new employees on July 1, 2020.
(7)
Pursuant to the Registrant
'
s non-qualified stock option inducement awards to 11 new employees on August 3, 2020.
(8)
Pursuant to the Registrant
'
s non-qualified stock option inducement awards to 12 new employees on September 1, 2020.
(9)
Pursuant to the Registrant
'
s non-qualified stock option inducement awards to nine new employees on October 1, 2020.
(10)
Pursuant to the Registrant's non-qualified stock option inducement awards to 10 new employees on November 2, 2020.
(11)
Pursuant to the Registrant's non-qualified stock option inducement awards to seven new employees on December 1, 2020.
(12)
Pursuant to the Registrant's non-qualified stock option inducement awards to 14 new employees on February 1, 2021.
(13)
Pursuant to the Registrant's non-qualified stock option inducement awards to seven new employees on March 1, 2021.
(14)
Pursuant to the Registrant's non-qualified stock option inducement awards to eight new employees on April 1, 2021.
(15)
Pursuant to the Registrant's non-qualified stock option inducement awards to nine new employees on May 3, 2021 (together with the Registrant's non-qualified stock option inducement awards
                described in footnotes (4), (6), (7), (8), (9), (10), (11), (12), (13) and (14), the "Non-Qualified Stock Option Inducement Awards").
PART I
INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS
Item 1.
Plan Information.
Not required to be filed as part of this Registration Statement pursuant to the Note to Part I of Form S-8.
Item 2.
Registrant Information and Employee Plan Annual Information.
Not required to be filed as part of this Registration Statement pursuant to the Note to Part I of Form S-8.
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 3.
Incorporation of Documents by Reference.
The following documents, which have previously been filed by the Registrant with the Securities and Exchange Commission (the "Commission"), are incorporated by reference herein and shall be deemed to be a part hereof:
(1)
The Registrant's Annual Report on Form 10-K for the year ended December 31, 2020, filed with the Commission on February 25, 2021;
(2)
The Registrant's Quarterly Report on Form 10-Q for the quarter ended March 31, 2021, filed with the Commission on May 6, 2021;
(3)
The Registrant's Current Reports on Form 8-K filed with the Commission on February 25, 2021 (solely with respect to Item 1.01), May 13, 2021 (solely with respect to Item 8.01) and May 13, 2021 (solely with
                respect to Items 1.01 and 2.03); and
(4)
Description of the Registrant's common stock contained in its registration statement on Form 8-A, dated June 1, 2000, as updated by the Description of Securities Registered Under Section 12 of the Exchange Act,
                filed as Exhibit 4.5 to the Registrant's Annual Report on Form 10-K for the year ended December 31, 2020, and including any amendment or report subsequently filed for the purpose of updating such description.
In addition, subsequent to the date of this Registration Statement and prior to the filing of a post-effective amendment hereto that indicates all securities offered hereunder have been sold or deregisters all securities
      then remaining unsold, all reports and other documents filed by the Registrant pursuant to Section 13(a), 13(c), 14 or 15(d) of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), shall be deemed to be incorporated by reference
      herein and to be a part hereof from the date of filing of such documents;
provided, however
, that no information furnished (but not filed) under Item 2.02 or Item 7.01 of any Current Report on Form 8-K shall
      be incorporated by reference except to the extent specified in such Current Report on Form 8-K.
For purposes of this Registration Statement, any statement contained in a document incorporated or deemed to be incorporated herein by reference shall be deemed to be modified or superseded to the extent that a
      statement contained herein or in any subsequently filed document that also is incorporated or is deemed to be incorporated herein by reference modifies or supersedes such statement. Any statement so modified or superseded shall not be deemed, except
      as so modified or superseded, to constitute a part of this Registration Statement.
Item 4.
Description of Securities.
Not applicable.
Item 5.
Interests of Named Experts and Counsel.
Not applicable.
Item 6.
Indemnification of Directors and Officers.
The Virginia Stock Corporation Act (the "VSCA") permits, and the Registrant's Articles of Incorporation require, indemnification of the Registrant's directors and officers in a variety of circumstances, which may include
      indemnification for liabilities under the Securities Act. Under the VSCA, a Virginia corporation is generally authorized to indemnify its directors and officers in civil or criminal actions if they acted in good faith and believed their conduct to be
      in the best interests of the corporation and, in the case of criminal actions, had no reasonable cause to believe that the conduct was unlawful, or if they engaged in conduct for which broader indemnification has been made permissible or obligatory
      by the Registrant. The VSCA requires such indemnification, unless limited by a corporation's articles of incorporation, when a director or officer entirely prevails in the defense of any proceeding to which he or she was a party because he or she is
      or was a director or officer of the corporation. The VSCA provides that a corporation may make any other or further indemnity (including indemnity with respect to a proceeding by or in the right of the corporation), and may make additional provision
      for advances and reimbursement of expenses, if authorized by its articles of incorporation or shareholder-adopted bylaw or resolution, except an indemnity against willful misconduct or a knowing violation of the criminal law. The Registrant's
      Articles of Incorporation require indemnification of directors and officers with respect to certain liabilities, expenses and other amounts imposed upon them because of having been a director or officer, except in the case of willful misconduct or a
      knowing violation of criminal law.
The VSCA establishes a statutory limit on liability of directors and officers of a corporation for damages assessed against them in a suit brought by or in the right of the corporation or brought by or on behalf of the
      corporation's shareholders and authorizes a corporation to specify a lower monetary limit on liability (including the elimination of liability for monetary damages) in the corporation's articles of incorporation or shareholder-approved bylaws;
      however, the liability of a director or officer shall not be limited if such director or officer engaged in willful misconduct or a knowing violation of the criminal law or of any federal or state securities law, including, without limitation, any
      unlawful insider trading or manipulation of the market for any security. As permitted by the VSCA, the Registrant's Articles of Incorporation provide that no director or officer of the Registrant shall be liable to the Registrant or the Registrant's
      shareholders for monetary damages with respect to any transaction, occurrence or course of conduct, except for liability resulting from such person's having engaged in willful misconduct or a knowing violation of the criminal law or any federal or
      state securities law.
Certain directors and officers have been granted contractual indemnification rights under separate indemnification agreements with the Registrant, pursuant to which they will be entitled to indemnification from the
      Registrant under certain circumstances. Additionally, the employment agreements the Registrant has entered into with its executive officers provide for indemnification to the fullest extent permitted by law from and against any and all claims,
      damages, expenses (including attorneys' fees), judgments, penalties, fines, settlements, and all other liabilities incurred or paid by the executive officer in connection with the investigation, defense, prosecution, settlement or appeal of any
      threatened, pending or completed action, suit or proceeding, whether civil, criminal, administrative or investigative in nature, and to which the executive officer was or is a party or is threatened to be made a party by reason of the fact that he or
      she is or was an officer, employee or agent of the Registrant, or by reason of anything done or not done by him or her in any such capacity or capacities, provided that such executive officer acted in good faith, in a manner that was not grossly
      negligent or that constituted willful misconduct and in a manner he or she reasonably believed to be in or not opposed to the Registrant's best interests, and, with respect to any criminal action or proceeding, had no reasonable cause to believe his
      or her conduct was unlawful. The Registrant also carries insurance on behalf of directors, officers, employees or agents that may cover liabilities under the Securities Act.
Item 7.
Exemption From Registration Claimed.
Not applicable.
Item 8.
Exhibits.
A list of exhibits included in this Registration Statement is set forth on the Exhibit Index and is incorporated herein by reference.
Item 9.
Undertakings.
(a)
The undersigned Registrant hereby undertakes:
(1)
To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:
(i)
To include any prospectus required by Section 10(a)(3) of the Securities Act;
(ii)
To reflect in the prospectus any facts or events arising after the effective date of the Registration Statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate,
                represent a fundamental change in the information set forth in the Registration Statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities offered would not
                exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the
                changes in volume and price represent no more than 20 percent change in the maximum aggregate offering price set forth in the "Calculation of Registration Fee" table in the effective registration statement; and
(iii)
To include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement or any material change to such information in the Registration Statement;
provided, however
, that paragraphs (a)(1)(i) and (a)(1)(ii) do not apply if the information required to be included in a post-effective amendment by those paragraphs is
      contained in reports filed with or furnished to the Commission by the Registrant pursuant to Section 13 or Section 15(d) of the Exchange Act that are incorporated by reference in the Registration Statement;
(2)
That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered therein, and
                the offering of such securities at that time shall be deemed to be the initial
bona fide
offering thereof; and
(3)
To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.
(b)
The undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the Registrant's annual report pursuant to Section 13(a) or Section 15(d) of
                the Exchange Act (and, where applicable, each filing of an employee benefit plan's annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in the Registration Statement shall be deemed to be a new
                registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial
bona fide
offering thereof.
(c)
Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the Registrant pursuant to the foregoing provisions, or otherwise,
                the Registrant has been advised that in the opinion of the Commission such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification against
                such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such
                director, officer or controlling person in connection with the securities being registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate
                jurisdiction the question whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.
EXHIBIT INDEX
Exhibit No.
Exhibit Description
4.1
Insmed Incorporated 2019 Incentive Plan (incorporated by reference from Exhibit 10.1 to Insmed Incorporated's Quarterly Report on Form 10-Q, filed on August 1, 2019).
4.2
Amendment No. 1 to Insmed Incorporated 2019 Incentive Plan (incorporated by reference from Appendix A to Insmed Incorporated's Proxy Statement on Schedule 14A, filed on March 31, 2020).
4.3
Omnibus Amendment to Insmed Incorporated Incentive Plans (incorporated by reference from Exhibit 10.6 to Insmed Incorporated's Annual Report on Form 10-K, filed on February 25, 2021).
4.4
Amendment No. 2 to Insmed Incorporated 2019 Incentive Plan (incorporated by reference from Appendix A to Insmed Incorporated's Proxy Statement on Schedule 14A, filed on April 1, 2021).
4.5
Form of Insmed Incorporated Non-Qualified Stock Option Inducement Award Agreement (incorporated by reference from Exhibit 10.6 to Insmed Incorporated's Quarterly Report on Form 10-Q, filed on August 3, 2017).
5.1*
Opinion of Hunton Andrews Kurth LLP.
23.1*
Consent of Hunton Andrews Kurth LLP (included in Exhibit 5.1).
23.2*
Consent of Ernst & Young LLP, Independent Registered Public Accounting Firm.
24.1
Power of Attorney (included on signature page hereto).
*
Filed herewith.
SIGNATURES
Pursuant to the requirements of the Securities Act, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration
      Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Bridgewater, State of New Jersey, on May 19, 2021.
INSMED INCORPORATED
By:
/s/ William H. Lewis
William H. Lewis
Chairman, President and Chief Executive Officer
POWER OF ATTORNEY
KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Christine Pellizzari his or her true and lawful attorney with power of substitution and resubstitution to sign
      in his or her name, place and stead in any and all such capacities the Registration Statement and any and all amendments and supplements thereto (including post-effective amendments) and documents in connection therewith, and to file the same with
      the Commission, said attorney to have full power and authority to do and perform, in the name of and on behalf of each of said officers and directors of the Registrant who shall have executed such a power of attorney, every act whatsoever which such
      attorney may deem necessary or desirable to be done in connection therewith, as fully and to all intents and purposes as such officer or director of the Registrant might or could do in person.
Pursuant to the requirements of the Securities Act, this Registration Statement has been signed by the following persons in the capacities and on the dates indicated.
Signature
Title
Date
/s/ William H. Lewis
President and Chief Executive Officer; Chairman of the Board of Directors
(
Principal Executive Officer
)
May 19, 2021
William H. Lewis
/s/ Sara Bonstein
Chief Financial Officer
(
Principal Financial Officer, Principal Accounting Officer
)
May 19, 2021
Sara Bonstein
*
Director
May 19, 2021
Alfred F. Altomari
*
Director
May 19, 2021
Elizabeth McKee Anderson
*
Director
May 19, 2021
David R. Brennan
*
Director
May 19, 2021
Clarissa Desjardins, Ph.D.
*
Director
May 19, 2021
Steinar J. Engelsen, M.D.
*
Director
May 19, 2021
Leo Lee
*
Director
May 19, 2021
David W.J. McGirr
*
Director
May 19, 2021
Carol A. Schafer
*
Director
May 19, 2021
Melvin Sharoky, M.D.
* By:
/s/ Christine Pellizzari
Christine Pellizzari
Attorney-in-Fact