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  <p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>As filed with the U.S. Securities and Exchange Commission on July 6,
        2022</b></font></p>
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  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Registration No. 333-</b></font></p>
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  <p style="font: 18pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 18pt"><b>UNITED STATES</b></font></p>
  <p style="font: 18pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 18pt"><b>SECURITIES AND EXCHANGE COMMISSION</b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 12pt"><b>Washington, D.C. 20549</b></font></p>
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  <p style="font: 18pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 18pt"><b>FORM S-8</b></font></p>
  <p style="font: 18pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 18pt"><b>REGISTRATION STATEMENT</b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 12pt"><b><i>UNDER</i></b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 12pt"><b><i>THE SECURITIES ACT OF 1933 </i></b></font></p>
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  <p style="font: 24pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 24pt"><b>ENTEGRIS, INC.</b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>(Exact name of registrant as specified in its charter) </b></font></p>
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        <td style="font: 10pt Times New Roman, Times, Serif; text-align: center; width: 50%"><font style="font-family: Times New Roman, Times, Serif;"><b>Delaware</b></font></td>
        <td style="font: 10pt Times New Roman, Times, Serif; text-align: center; width: 50%"><font style="font-family: Times New Roman, Times, Serif;"><b>41-1941551</b></font></td>
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          <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif;"><b>(State or other jurisdiction of&#160;</b></font></p>
          <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif;"><b>incorporation or organization)</b></font></p>
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          <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif;"><b>(I.R.S. Employer</b></font></p>
          <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif;"><b>Identification No.)</b></font></p>
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        <td style="font: 10pt Times New Roman, Times, Serif; text-align: center"><font style="font-family: Times New Roman, Times, Serif;"><b>129 Concord Road, Billerica, MA</b></font></td>
        <td style="font: 10pt Times New Roman, Times, Serif; text-align: center"><font style="font-family: Times New Roman, Times, Serif;"><b>01821</b></font></td>
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        <td style="font: 10pt Times New Roman, Times, Serif; text-align: center"><font style="font-family: Times New Roman, Times, Serif;"><b>(Address of Principal Executive Offices)</b></font></td>
        <td style="font: 10pt Times New Roman, Times, Serif; text-align: center"><font style="font-family: Times New Roman, Times, Serif;"><b>(Zip Code)</b></font></td>
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  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Entegris, Inc. 2020 Stock Plan</b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>CMC Materials, Inc. 2021 Omnibus Incentive Plan</b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Cabot Microelectronics Corporation 2012 Omnibus Incentive Plan</b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>(Full title of the plan)</b></font></p>
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  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Joseph Colella, Esq.</b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Senior Vice President, General Counsel and Secretary</b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Entegris, Inc.</b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>129 Concord Road </b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Billerica, MA 01821</b>&#160;</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>(978) 436-6500</b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>(Name, address and telephone number, including area code, of agent for service) </b></font></p>
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  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a
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        <td style="font: 10pt Times New Roman, Times, Serif; width: 12%"><font style="font-family: Times New Roman, Times, Serif;">&#9746;</font></td>
        <td style="width: 6%"><font style="font-family: Times New Roman, Times, Serif;">&#160;</font></td>
        <td style="font: 10pt Times New Roman, Times, Serif; width: 35%"><font style="font-family: Times New Roman, Times, Serif;">Accelerated filer</font></td>
        <td style="font: 10pt Times New Roman, Times, Serif; width: 12%"><font style="font-family: Times New Roman, Times, Serif;">&#9744;</font></td>
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        <td style="font: 10pt Times New Roman, Times, Serif">&#160;</td>
        <td>&#160;</td>
        <td style="font: 10pt Times New Roman, Times, Serif">&#160;</td>
        <td style="font: 10pt Times New Roman, Times, Serif">&#160;</td>
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        <td style="font: 10pt Times New Roman, Times, Serif"><font style="font-family: Times New Roman, Times, Serif;">Non-accelerated filer</font></td>
        <td style="font: 10pt Times New Roman, Times, Serif"><font style="font-family: Times New Roman, Times, Serif;">&#9744;</font></td>
        <td><font style="font-family: Times New Roman, Times, Serif;">&#160;</font></td>
        <td style="font: 10pt Times New Roman, Times, Serif"><font style="font-family: Times New Roman, Times, Serif;">Smaller reporting company</font></td>
        <td style="font: 10pt Times New Roman, Times, Serif"><font style="font-family: Times New Roman, Times, Serif;">&#9744;</font></td>
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        <td style="font: 10pt Times New Roman, Times, Serif">&#160;</td>
        <td style="font: 10pt Times New Roman, Times, Serif">&#160;</td>
        <td>&#160;</td>
        <td style="font: 10pt Times New Roman, Times, Serif">&#160;</td>
        <td style="font: 10pt Times New Roman, Times, Serif">&#160;</td>
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        <td style="font: 10pt Times New Roman, Times, Serif"><font style="font-family: Times New Roman, Times, Serif;">Emerging growth company</font></td>
        <td style="font: 10pt Times New Roman, Times, Serif"><font style="font-family: Times New Roman, Times, Serif;">&#9744;</font></td>
        <td><font style="font-family: Times New Roman, Times, Serif;">&#160;</font></td>
        <td><font style="font-family: Times New Roman, Times, Serif;">&#160;</font></td>
        <td><font style="font-family: Times New Roman, Times, Serif;">&#160;</font></td>
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  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.25pt">&#160;</p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.25pt"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">If an emerging growth company, indicate by check mark if the registrant has elected not to use the
      extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. &#9744;</font></p>
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  <p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt; background-color: white"><b>EXPLANATORY NOTE</b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">This Registration Statement on Form S-8 is filed by Entegris, Inc., a
      Delaware corporation (the &#8220;Registrant&#8221;), to register up to 4,869,064 shares of its common stock, par value $0.01 per share (the &#8220;Common Stock&#8221;), issuable in connection with the Entegris, Inc. 2020 Stock Plan (the &#8220;Entegris 2020 Plan&#8221;), CMC Materials,
      Inc. 2021 Omnibus Incentive Plan (the &#8220;CMC 2021 Plan&#8221;) and Cabot Microelectronics Corporation 2012 Omnibus Incentive Plan, as amended (the &#8220;CMC 2012 Plan&#8221; and together with the CMC 2021 Plan, the &#8220;CMC Plans&#8221;) under the Securities Act of 1933, as
      amended (the &#8220;Securities Act&#8221;).</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">On December 14, 2021, the Registrant, CMC Materials, Inc. (&#8220;CMC&#8221;), and
      Yosemite Merger Sub, Inc., a wholly owned subsidiary of the Registrant (&#8220;Merger Sub&#8221;) entered into an Agreement and Plan of Merger (the &#8220;Merger Agreement&#8221;). On July 6, 2022, and in accordance with the terms of the Merger Agreement, Merger Sub merged
      with and into CMC, and CMC continued as the surviving corporation and a wholly owned subsidiary of the Registrant (the &#8220;Merger&#8221;).</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Pursuant to and subject to the terms of the Merger Agreement, the
      Registrant assumed the CMC Plans in accordance with their terms, including stock options (the &#8220;Adjusted CMC Options&#8221;) and certain performance-based restricted stock units of CMC outstanding under the CMC Plans (the &#8220;Adjusted CMC PSUs&#8221;), which are
      settleable in shares of the Registrant&#8217;s Common Stock, generally subject to the terms and conditions of the underlying award agreements. The aggregate number of the Registrant&#8217;s Common Stock subject to the Adjusted CMC Options and the Adjusted CMC
      PSUs under the CMC 2021 Plan and the CMC 2012 Plan is 799,042 and 148,368 shares, respectively. In addition, the Registrant has reserved 3,921,654 shares of Common Stock, which constitute the unused share reserve under the CMC 2021 Plan, that may be
      issued for future awards granted by the Registrant under the Entegris 2020 Plan.</font></p>
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  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt; background-color: white"><b>PART I</b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font: 10pt Times New Roman, Times, Serif; background-color: white"><b>Information Required in the Section 10(a) Prospectus</b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt; background-color: white">The information required by Part I is included
      in the documents sent or given to participants in the Plan, pursuant to Rule 428(b)(1) of the Securities Act. Such documents are not required to be, and are not, filed with the Securities and Exchange Commission (the &#8220;SEC&#8221;) either as part of this
      Registration Statement or as a prospectus or prospectus supplement pursuant to Rule 424 under the Securities Act. These documents and the documents incorporated by reference in this Registration Statement pursuant to Item 3 of Part II of Form S-8,
      taken together, constitute a prospectus that meets the requirements of Section 10(a) of the Securities Act.</font></p>
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  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>PART II</b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font: 10pt Times New Roman, Times, Serif"><b>INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</b></font></p>
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        <td style="font: 10pt Times New Roman, Times, Serif; text-align: justify; width: 0.75in"><font style="font-family: Times New Roman, Times, Serif;"><b>Item 3.</b></font></td>
        <td style="font: 10pt Times New Roman, Times, Serif; text-align: justify"><font style="font-family: Times New Roman, Times, Serif;"><b>Incorporation of Documents by Reference.</b></font></td>
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  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The following documents filed with the Commission are hereby
      incorporated by reference and shall be deemed to be a part of this Registration Statement:</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</font></p>
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        <td style="text-align: justify; width: 0.25in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(a)</font></td>
        <td style="text-align: justify">
          <div><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">the Registrant&#8217;s Annual Report on Form 10-K for the fiscal year ended December 31, 2021 (No. 001-32598), as filed with the SEC on <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1101302/000110130222000010/entg-20211231.htm">February 4, 2022</a>;</font></div>
          <div><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"> <br>
            </font></div>
        </td>
      </tr>
      <tr style="vertical-align: top">
        <td style="text-align: justify"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(b)</font></td>
        <td style="text-align: justify">
          <div><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">the Registrant&#8217;s Schedule 14A proxy statement for its 2022 annual meeting of stockholders (No. 001-32598), as filed with the SEC on <a href="https://www.sec.gov/Archives/edgar/data/1101302/000110130222000014/a2022proxystatement.htm">March 17, 2022</a>;</font></div>
          <div><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"> <br>
            </font></div>
        </td>
      </tr>
      <tr style="vertical-align: top">
        <td style="text-align: justify"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(c)</font></td>
        <td style="text-align: justify">
          <div><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">the Registrant&#8217;s Quarterly Report on Form 10-Q for the three months ended April 2, 2022 (No. 001-32598), as filed with the SEC on <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1101302/000110130222000024/entg-20220402.htm">April 26, 2022</a>;</font></div>
          <div><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"> <br>
            </font></div>
        </td>
      </tr>
      <tr style="vertical-align: top">
        <td style="text-align: justify"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(d)</font></td>
        <td style="text-align: justify">
          <div><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">the Registrant&#8217;s Current Reports on Form 8-K (No. 001-32598), as filed with the SEC on <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1101302/000110130222000002/entg-20220119.htm">January 19, 2022</a>, <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1101302/000114036122003191/ny20001665x23_8k.htm">January 31,
                2022</a>, <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1101302/000114036122013228/ny20003000x4_8k.htm">April 6, 2022</a>, <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1101302/000110130222000016/entg-20220406.htm">April










                8, 2022</a>, <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1101302/000114036122014648/ny20003659x3_8k.htm">April 15, 2022</a>, <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1101302/000110130222000018/entg-20220420.htm">April 20, 2022</a>, <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1101302/000110130222000026/entg-20220427.htm">April 27, 2022</a>,
              <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1101302/000114036122023175/ny20003790x2_8k.htm">June 16, 2022</a>, <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1101302/000114036122023343/ny20003790x3_8k.htm">June 17,
                2022</a>, <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1101302/000114036122024601/ny20004647x1_8k.htm">June 30, 2022</a> and <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1101302/000114036122025275/ny20004647x3_8k.htm">July 6, 2022</a>;</font></div>
          <div><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"> <br>
            </font></div>
        </td>
      </tr>
      <tr style="vertical-align: top">
        <td style="text-align: justify"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(e)</font></td>
        <td style="text-align: justify">
          <div><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">the description of the Registrant&#8217;s Common Stock contained in the Registrant&#8217;s registration statement on Form 8-A filed with the SEC on <a href="https://www.sec.gov/Archives/edgar/data/1101302/000104596900000486/0001045969-00-000486-0001.txt">June 30, 2000</a>, as updated by the description of the Registrant&#8217;s Common Stock contained in Exhibit 4.1 to its Annual Report on Form
              10-K for the fiscal year ended December 31, 2019 (No. 001-32598) filed with the SEC on <a href="https://www.sec.gov/Archives/edgar/data/1101302/000110130220000013/entg-12312019xex41.htm">February 7, 2020</a>, and including any amendment or
              report filed for the purpose of updating such description; and</font></div>
          <div><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"> <br>
            </font></div>
        </td>
      </tr>
      <tr style="vertical-align: top">
        <td style="text-align: justify"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(f)</font></td>
        <td style="text-align: justify"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">All documents filed by the Registrant pursuant to Sections 13(a), 13(c), 14, and 15(d) of the Securities Exchange Act of 1934, as amended,
            after the date of this Registration Statement and prior to the filing of a post-effective amendment to this Registration Statement indicating that all securities offered have been sold or that deregisters the distribution of all securities then
            remaining unsold, will be deemed to be incorporated by reference into this Registration Statement and will be a part of this Registration Statement from the date such document is filed, except as to any information that the Registrant discloses
            under Items 2.02, 7.01 or 9.01 of any Current Report on Form 8-K that is deemed to be furnished and not filed under such provisions.</font></td>
      </tr>

  </table>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&#160;</p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Any statement contained in a document incorporated or deemed to be
      incorporated by reference herein shall be deemed to be modified or superseded for the purposes of this Registration Statement to the extent that a statement contained in this Registration Statement or in any other subsequently filed document that
      also is or is deemed to be incorporated by reference herein modifies or supersedes such statement. Any statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this Registration Statement.</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Item 4. Description of Securities.</b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Not applicable.</font></p>
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    <div id="DSPFPageNumberArea" style="TEXT-ALIGN: center"><font id="DSPFPageNumber" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-WEIGHT: normal; COLOR: #000000; FONT-STYLE: normal">&#160;</font></div>
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  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Item 5. Interests of Named Experts and Counsel.</b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The validity of the securities registered hereby is being passed by
      Skadden, Arps, Slate, Meagher &amp; Flom LLP, New York, New York, as legal counsel.<br>
      <sup style="vertical-align: text-top; line-height: 1; font-size: smaller;"></sup></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&#160;</p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Item 6. Indemnification of Officers and Directors.</b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The Registrant is incorporated under the laws of the State of Delaware.
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      threatened to be made parties to any threatened, pending or completed action, suit or proceeding, whether civil, criminal, administrative or investigative (other than an action by or in the right of such corporation), by reason of the fact that such
      person is or was an officer, director, employee or agent of such corporation, or is or was serving at the request of such corporation as a director, officer, employee or agent of another corporation or enterprise. The indemnity may include expenses
      (including attorneys&#8217; fees), judgments, fines and amounts paid in settlement actually and reasonably incurred by such person in connection with such action, suit or proceeding, provided that such person acted in good faith and in a manner he or she
      reasonably believed to be in or not opposed to the corporation&#8217;s best interests and, with respect to any criminal action or proceeding, had no reasonable cause to believe that his or her conduct was illegal.</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</font></p>
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      insurance on behalf of any person who is or was a director, officer, employee or agent of the corporation, or is or was serving at the request of the corporation as a director, officer, employee or agent of another corporation or enterprise, against
      any liability asserted against him or her and incurred by him or her in any such capacity, arising out of his or her status as such, whether or not the corporation would otherwise have the power to indemnify him or her under Section 145.</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The Registrant&#8217;s certificate of incorporation provides that the
      Registrant&#8217;s directors shall not be liable to the corporation or its stockholders for monetary damages for breach of fiduciary duty as a director, except to the extent that the exculpation from liabilities is not permitted under the DGCL as in effect
      at the time such liability is determined. The Registrant&#8217;s certificate of incorporation provides that the corporation shall indemnify its directors to the full extent permitted by the laws of the State of Delaware. In addition, the Registrant&#8217;s
      bylaws provide for indemnification of the registrant&#8217;s officers and directors to the fullest extent permitted by applicable law.</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">All of the Registrant&#8217;s directors and officers are covered by insurance
      policies maintained by the Registrant against specified liabilities for actions taken in their capacities as such, including liabilities under the Securities Act.</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The Registrant has entered into indemnification agreements with its
      directors and certain of its executive officers providing for the indemnification of such director or executive officer, as applicable, to the extent legally permissible and the payment of expenses, including counsel fees reasonably incurred in
      connection with the defense or disposition of any action, suit or other proceeding in which such individual may be involved by reason of such individual being or having been a director or officer of the Registrant.</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></p>
  <!-- Field: Rule-Page -->
  <div id="DSPFPageBreakArea" style="MARGIN-BOTTOM: 10pt; CLEAR: both; MARGIN-TOP: 10pt">
    <div id="DSPFPageNumberArea" style="TEXT-ALIGN: center"><font id="DSPFPageNumber" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-WEIGHT: normal; COLOR: #000000; FONT-STYLE: normal">&#160;</font></div>
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  </div>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Item 7.</b>&#160;<b>Exemption From Registration Claimed. </b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Not applicable.</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Item 8. Exhibits.</b></font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</font></p>
  <table style="font: 10pt Times New Roman, Times, Serif; width: 100%" cellpadding="0" cellspacing="0">

      <tr>
        <td style="vertical-align: bottom; text-align: center; width: 8%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;<b>Exhibit <br>
              <u>Number</u></b></font></td>
        <td style="width: 1%">&#160;</td>
        <td style="vertical-align: bottom; text-align: left; width: 91%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><u>Description</u></b></font></td>
      </tr>
      <tr style="vertical-align: top">
        <td style="text-align: center"><a href="https://www.sec.gov/Archives/edgar/data/1101302/000119312520077116/d860226ddef14a.htm#toc860226_57"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">4.1</font></a></td>
        <td>&#160;</td>
        <td style="text-align: justify"><a href="https://www.sec.gov/Archives/edgar/data/1101302/000119312520077116/d860226ddef14a.htm#toc860226_57"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt; ">Entegris, Inc. 2020 Stock Plan
              (incorporated by reference to Annex 1 to the Registrant&#8217;s Schedule 14A proxy statement for its 2020 annual meeting of stockholders (No. 001-32598), as filed with the SEC on March 18, 2020).</font></a></td>
      </tr>
      <tr style="vertical-align: top">
        <td style="text-align: center"><a href="https://www.sec.gov/Archives/edgar/data/1102934/000119312521010972/d41869ddef14a.htm#toc41869_59"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">4.2</font></a></td>
        <td>&#160;</td>
        <td style="text-align: justify"><a href="https://www.sec.gov/Archives/edgar/data/1102934/000119312521010972/d41869ddef14a.htm#toc41869_59"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt; ">CMC Materials, Inc. 2021 Omnibus
              Incentive Plan (incorporated by reference to Appendix B to CMC Materials, Inc.&#8217;s Schedule 14A proxy statement for its 2021 annual meeting of stockholders (No. 000-30205), as filed with the SEC on January 19, 2021).</font></a></td>
      </tr>
      <tr style="vertical-align: top">
        <td style="text-align: center"><a href="ny20004700x2_ex4-3.htm"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">4.3</font></a></td>
        <td>&#160;</td>
        <td style="text-align: justify"><a href="ny20004700x2_ex4-3.htm"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt; ">Amendment Number 1 to the CMC Materials, Inc. 2021 Omnibus Incentive Plan.*</font></a></td>
      </tr>
      <tr style="vertical-align: top">
        <td style="text-align: center"><a href="http://www.sec.gov/Archives/edgar/data/1102934/000110293420000055/ex108cmcmaterialsinc20.htm"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">4.4</font></a></td>
        <td>&#160;</td>
        <td style="text-align: justify"><a href="http://www.sec.gov/Archives/edgar/data/1102934/000110293420000055/ex108cmcmaterialsinc20.htm"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt; ">CMC Materials, Inc. 2012 Omnibus
              Incentive Plan, as amended effective March 7, 2017 (incorporated by reference to Exhibit 10.8 to CMC Materials, Inc.&#8217;s Annual Report on Form 10-K (No. 000-30205), as filed with the SEC on November 17, 2020).</font></a></td>
      </tr>
      <tr style="vertical-align: top">
        <td style="text-align: center"><a href="ny20004700x2_ex5-1.htm"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.1</font></a></td>
        <td>&#160;</td>
        <td style="text-align: justify"><a href="ny20004700x2_ex5-1.htm"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt; ">Opinion of Skadden, Arps, Slate, Meagher and Flom LLP.*</font></a></td>
      </tr>
      <tr style="vertical-align: top">
        <td style="text-align: center"><a href="ny20004700x2_ex5-1.htm"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">23.1</font></a></td>
        <td>&#160;</td>
        <td style="text-align: justify"><a href="ny20004700x2_ex5-1.htm"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt; ">Consent of Skadden, Arps, Slate, Meagher and Flom LLP (included in the opinion
              filed as Exhibit 5.1).*</font></a></td>
      </tr>
      <tr style="vertical-align: top">
        <td style="text-align: center"><a href="ny20004700x2_ex23-2.htm"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">23.2</font></a></td>
        <td>&#160;</td>
        <td style="text-align: justify"><a href="ny20004700x2_ex23-2.htm"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt; ">Consent of KPMG LLP.*</font></a></td>
      </tr>
      <tr style="vertical-align: top">
        <td rowspan="1" style="text-align: center"><a href="ny20004700x2_ex23-3.htm">23.3<br>
          </a> </td>
        <td rowspan="1">&#160;</td>
        <td rowspan="1" style="text-align: justify"><a href="ny20004700x2_ex23-3.htm">Consent of PricewaterhouseCoopers LLP*<br>
          </a> </td>
      </tr>
      <tr style="vertical-align: top">
        <td style="text-align: center"><a href="#pow"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">24.1</font></a></td>
        <td>&#160;</td>
        <td style="text-align: justify"><a href="#pow"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt; ">Power of Attorney (included on the signature page hereto).*</font></a></td>
      </tr>
      <tr style="vertical-align: top">
        <td style="text-align: center"><a href="ny20004700x2_ex107.htm"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">107</font></a></td>
        <td>&#160;</td>
        <td style="text-align: justify"><a href="ny20004700x2_ex107.htm"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt; ">Filing Fee Table.*</font></a></td>
      </tr>

  </table>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&#160;</p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">*Filed herewith.</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</font></p>
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  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(a) The undersigned Registrant hereby undertakes:</font></p>
  <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</font></p>
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{"company-data": {"conformed-name": "ENTEGRIS INC", "cik": "0001101302", "assigned-sic": "3089", "irs-number": "411941551", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-266040", "film-number": "221070208"}, "business-address": {"street1": "129 CONCORD ROAD", "city": "BILLERICA", "state": "MA", "zip": "01821", "phone": "9784366500"}, "mail-address": {"street1": "129 CONCORD ROAD", "city": "BILLERICA", "state": "MA", "zip": "01821"}}
As filed with the U.S. Securities and Exchange Commission on July 6,
        2022
Registration No. 333-
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-8
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
ENTEGRIS, INC.
(Exact name of registrant as specified in its charter)
Delaware
41-1941551
(State or other jurisdiction of
incorporation or organization)
(I.R.S. Employer
Identification No.)
129 Concord Road, Billerica, MA
01821
(Address of Principal Executive Offices)
(Zip Code)
Entegris, Inc. 2020 Stock Plan
CMC Materials, Inc. 2021 Omnibus Incentive Plan
Cabot Microelectronics Corporation 2012 Omnibus Incentive Plan
(Full title of the plan)
Joseph Colella, Esq.
Senior Vice President, General Counsel and Secretary
Entegris, Inc.
129 Concord Road
Billerica, MA 01821
(978) 436-6500
(Name, address and telephone number, including area code, of agent for service)
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a
      non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of "large accelerated filer," "accelerated filer," "smaller reporting company" and "emerging growth company" in Rule 12b-2 of the Exchange Act.
Large accelerated filer
☒
Accelerated filer
☐
Non-accelerated filer
☐
Smaller reporting company
☐
Emerging growth company
☐
If an emerging growth company, indicate by check mark if the registrant has elected not to use the
      extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐
EXPLANATORY NOTE
This Registration Statement on Form S-8 is filed by Entegris, Inc., a
      Delaware corporation (the "Registrant"), to register up to 4,869,064 shares of its common stock, par value $0.01 per share (the "Common Stock"), issuable in connection with the Entegris, Inc. 2020 Stock Plan (the "Entegris 2020 Plan"), CMC Materials,
      Inc. 2021 Omnibus Incentive Plan (the "CMC 2021 Plan") and Cabot Microelectronics Corporation 2012 Omnibus Incentive Plan, as amended (the "CMC 2012 Plan" and together with the CMC 2021 Plan, the "CMC Plans") under the Securities Act of 1933, as
      amended (the "Securities Act").
On December 14, 2021, the Registrant, CMC Materials, Inc. ("CMC"), and
      Yosemite Merger Sub, Inc., a wholly owned subsidiary of the Registrant ("Merger Sub") entered into an Agreement and Plan of Merger (the "Merger Agreement"). On July 6, 2022, and in accordance with the terms of the Merger Agreement, Merger Sub merged
      with and into CMC, and CMC continued as the surviving corporation and a wholly owned subsidiary of the Registrant (the "Merger").
Pursuant to and subject to the terms of the Merger Agreement, the
      Registrant assumed the CMC Plans in accordance with their terms, including stock options (the "Adjusted CMC Options") and certain performance-based restricted stock units of CMC outstanding under the CMC Plans (the "Adjusted CMC PSUs"), which are
      settleable in shares of the Registrant's Common Stock, generally subject to the terms and conditions of the underlying award agreements. The aggregate number of the Registrant's Common Stock subject to the Adjusted CMC Options and the Adjusted CMC
      PSUs under the CMC 2021 Plan and the CMC 2012 Plan is 799,042 and 148,368 shares, respectively. In addition, the Registrant has reserved 3,921,654 shares of Common Stock, which constitute the unused share reserve under the CMC 2021 Plan, that may be
      issued for future awards granted by the Registrant under the Entegris 2020 Plan.
PART I
Information Required in the Section 10(a) Prospectus
The information required by Part I is included
      in the documents sent or given to participants in the Plan, pursuant to Rule 428(b)(1) of the Securities Act. Such documents are not required to be, and are not, filed with the Securities and Exchange Commission (the "SEC") either as part of this
      Registration Statement or as a prospectus or prospectus supplement pursuant to Rule 424 under the Securities Act. These documents and the documents incorporated by reference in this Registration Statement pursuant to Item 3 of Part II of Form S-8,
      taken together, constitute a prospectus that meets the requirements of Section 10(a) of the Securities Act.
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 3.
Incorporation of Documents by Reference.
The following documents filed with the Commission are hereby
      incorporated by reference and shall be deemed to be a part of this Registration Statement:
(a)
the Registrant's Annual Report on Form 10-K for the fiscal year ended December 31, 2021 (No. 001-32598), as filed with the SEC on
February 4, 2022
;
(b)
the Registrant's Schedule 14A proxy statement for its 2022 annual meeting of stockholders (No. 001-32598), as filed with the SEC on
March 17, 2022
;
(c)
the Registrant's Quarterly Report on Form 10-Q for the three months ended April 2, 2022 (No. 001-32598), as filed with the SEC on
April 26, 2022
;
(d)
the Registrant's Current Reports on Form 8-K (No. 001-32598), as filed with the SEC on
January 19, 2022
,
January 31,
                2022
,
April 6, 2022
,
April

                8, 2022
,
April 15, 2022
,
April 20, 2022
,
April 27, 2022
,
June 16, 2022
,
June 17,
                2022
,
June 30, 2022
and
July 6, 2022
;
(e)
the description of the Registrant's Common Stock contained in the Registrant's registration statement on Form 8-A filed with the SEC on
June 30, 2000
, as updated by the description of the Registrant's Common Stock contained in Exhibit 4.1 to its Annual Report on Form
              10-K for the fiscal year ended December 31, 2019 (No. 001-32598) filed with the SEC on
February 7, 2020
, and including any amendment or
              report filed for the purpose of updating such description; and
(f)
All documents filed by the Registrant pursuant to Sections 13(a), 13(c), 14, and 15(d) of the Securities Exchange Act of 1934, as amended,
            after the date of this Registration Statement and prior to the filing of a post-effective amendment to this Registration Statement indicating that all securities offered have been sold or that deregisters the distribution of all securities then
            remaining unsold, will be deemed to be incorporated by reference into this Registration Statement and will be a part of this Registration Statement from the date such document is filed, except as to any information that the Registrant discloses
            under Items 2.02, 7.01 or 9.01 of any Current Report on Form 8-K that is deemed to be furnished and not filed under such provisions.
Any statement contained in a document incorporated or deemed to be
      incorporated by reference herein shall be deemed to be modified or superseded for the purposes of this Registration Statement to the extent that a statement contained in this Registration Statement or in any other subsequently filed document that
      also is or is deemed to be incorporated by reference herein modifies or supersedes such statement. Any statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this Registration Statement.
Item 4. Description of Securities.
Not applicable.
Item 5. Interests of Named Experts and Counsel.
The validity of the securities registered hereby is being passed by
      Skadden, Arps, Slate, Meagher & Flom LLP, New York, New York, as legal counsel.
Item 6. Indemnification of Officers and Directors.
The Registrant is incorporated under the laws of the State of Delaware.
      Section 145 ("Section 145") of the General Corporation Law of the State of Delaware, as the same exists or may hereafter be amended (the "DGCL"),
inter alia
, provides that a Delaware corporation may indemnify any persons who were, are or are
      threatened to be made parties to any threatened, pending or completed action, suit or proceeding, whether civil, criminal, administrative or investigative (other than an action by or in the right of such corporation), by reason of the fact that such
      person is or was an officer, director, employee or agent of such corporation, or is or was serving at the request of such corporation as a director, officer, employee or agent of another corporation or enterprise. The indemnity may include expenses
      (including attorneys' fees), judgments, fines and amounts paid in settlement actually and reasonably incurred by such person in connection with such action, suit or proceeding, provided that such person acted in good faith and in a manner he or she
      reasonably believed to be in or not opposed to the corporation's best interests and, with respect to any criminal action or proceeding, had no reasonable cause to believe that his or her conduct was illegal.
Section 145 further authorizes a corporation to purchase and maintain
      insurance on behalf of any person who is or was a director, officer, employee or agent of the corporation, or is or was serving at the request of the corporation as a director, officer, employee or agent of another corporation or enterprise, against
      any liability asserted against him or her and incurred by him or her in any such capacity, arising out of his or her status as such, whether or not the corporation would otherwise have the power to indemnify him or her under Section 145.
The Registrant's certificate of incorporation provides that the
      Registrant's directors shall not be liable to the corporation or its stockholders for monetary damages for breach of fiduciary duty as a director, except to the extent that the exculpation from liabilities is not permitted under the DGCL as in effect
      at the time such liability is determined. The Registrant's certificate of incorporation provides that the corporation shall indemnify its directors to the full extent permitted by the laws of the State of Delaware. In addition, the Registrant's
      bylaws provide for indemnification of the registrant's officers and directors to the fullest extent permitted by applicable law.
All of the Registrant's directors and officers are covered by insurance
      policies maintained by the Registrant against specified liabilities for actions taken in their capacities as such, including liabilities under the Securities Act.
The Registrant has entered into indemnification agreements with its
      directors and certain of its executive officers providing for the indemnification of such director or executive officer, as applicable, to the extent legally permissible and the payment of expenses, including counsel fees reasonably incurred in
      connection with the defense or disposition of any action, suit or other proceeding in which such individual may be involved by reason of such individual being or having been a director or officer of the Registrant.
Item 7.
Exemption From Registration Claimed.
Not applicable.
Item 8. Exhibits.
Exhibit
Number
Description
4.1
Entegris, Inc. 2020 Stock Plan
              (incorporated by reference to Annex 1 to the Registrant's Schedule 14A proxy statement for its 2020 annual meeting of stockholders (No. 001-32598), as filed with the SEC on March 18, 2020).
4.2
CMC Materials, Inc. 2021 Omnibus
              Incentive Plan (incorporated by reference to Appendix B to CMC Materials, Inc.'s Schedule 14A proxy statement for its 2021 annual meeting of stockholders (No. 000-30205), as filed with the SEC on January 19, 2021).
4.3
Amendment Number 1 to the CMC Materials, Inc. 2021 Omnibus Incentive Plan.*
4.4
CMC Materials, Inc. 2012 Omnibus
              Incentive Plan, as amended effective March 7, 2017 (incorporated by reference to Exhibit 10.8 to CMC Materials, Inc.'s Annual Report on Form 10-K (No. 000-30205), as filed with the SEC on November 17, 2020).
5.1
Opinion of Skadden, Arps, Slate, Meagher and Flom LLP.*
23.1
Consent of Skadden, Arps, Slate, Meagher and Flom LLP (included in the opinion
              filed as Exhibit 5.1).*
23.2
Consent of KPMG LLP.*
23.3
Consent of PricewaterhouseCoopers LLP*
24.1
Power of Attorney (included on the signature page hereto).*
107
Filing Fee Table.*
*Filed herewith.
Item 9. Undertakings.
(a) The undersigned Registrant hereby undertakes:
(1) To file,
      during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:
(i) To include
      any prospectus required by Section 10(a)(3) of the Securities Act;
(ii) To reflect in the prospectus
      any facts or events arising after the effective date of this Registration Statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in this
      Registration Statement;
(iii) To include any material
      information with respect to the plan of distribution not previously disclosed in this Registration Statement or any material change to such information in this Registration Statement;
provided, however, that paragraphs (a) (1) (i) and (a) (1) (ii) do not apply if the
      information required to be included in a post-effective amendment by those paragraphs is contained in periodic reports filed by the Registrant pursuant to Section 13 or Section 15(d) of the Securities Exchange Act of 1934 that are incorporated by
      reference in this Registration Statement.
(2) That, for the purpose of determining any liability under
      the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide
      offering thereof.
(3) To remove from registration by means of a post-effective
      amendment any of the securities being registered which remain unsold at the termination of the offering.
(b) The undersigned Registrant hereby undertakes that, for purposes of
      determining any liability under the Securities Act, each filing of the Registrant's annual report pursuant to Section 13(a) or Section 15(d) of the Securities Exchange Act of 1934 that is incorporated by reference in this Registration Statement shall
      be deemed to be a new registration statement relating to the securities offered therein and the offering of such securities at that time shall be deemed to be initial bona fide offering thereof.
(c) Insofar as indemnification for liabilities arising under the
      Securities Act may be permitted to directors, officers and controlling persons of the Registrant pursuant to the provisions referred to in Item 6 hereof, or otherwise, the Registrant has been advised that in the opinion of the Securities and Exchange
      Commission such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the Registrant of expenses
      incurred or paid by a directors, officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer, or controlling person in connection with the securities being
      registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against public policy as
      expressed in the Securities Act and will be governed by the final adjudication of such issue.
SIGNATURES
Pursuant to the requirements of the Securities Act, as amended,
      Entegris, Inc. certifies that it has reasonable grounds to believe that it meets all the requirements for filing on Form S-8 and has duly caused this registration statement on Form S-8 to be signed on its behalf by the undersigned, thereunto duly
      authorized, in the Town of Billerica, Commonwealth of Massachusetts, on July 6, 2022.
ENTEGRIS, INC.
By
/s/ Bertrand Loy
Bertrand Loy
President and Chief Executive Officer
POWER OF ATTORNEY
We, the undersigned officers and directors of Entegris, Inc., hereby
      severally constitute and appoint each of Bertrand Loy, Gregory B. Graves and Joseph Colella our true and lawful attorneys-in-fact, with full power to them in any and all capacities, to sign any and all amendments to this Registration Statement on
      Form S-8 (including any post-effective amendments thereto), and to file the same, with exhibits thereto and other documents in connection therewith, with the Securities and Exchange Commission, hereby ratifying and confirming all that each of said
      attorneys-in-fact may do or cause to be done by virtue hereof.
Pursuant to the requirements of the Securities Act of 1933, this
      Registration Statement has been signed below by the following persons in the capacities and as of the dates indicated.
Signature
Title
Date
/s/ Bertrand Loy
Bertrand Loy
President, Chief Executive
Officer and Director
(Principal executive officer)
July 6, 2022
/s/ Gregory B. Graves
Gregory B. Graves
Executive Vice President,
Chief Financial Officer and Treasurer
(Principal financial officer)
July 6, 2022
/s/ Michael D. Sauer
Michael D. Sauer
Vice President, Controller and Chief Accounting Officer
(Principal accounting officer)
July 6, 2022
/s/ Paul L.H. Olson
Paul L.H. Olson
Director, Chairman of the Board
July 6, 2022
/s/ Michael A. Bradley
Michael A. Bradley
Director
July 6, 2022
/s/ Rodney Clark
Rodney Clark
Director
July 6, 2022
/s/ James F. Gentilcore
James F. Gentilcore
Director
July 6, 2022
/s/ Yvette Kanouff
Yvette Kanouff
Director
July 6, 2022
/s/ James P. Lederer
James P. Lederer
Director
July 6, 2022
/s/ Azita Saleki-Gerhardt
Azita Saleki-Gerhardt
Director
July 6, 2022