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<TITLE>August 15, 2019 S-8 DOC</TITLE>
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<FONT SIZE=2><B><P ALIGN="RIGHT">As filed with the Securities and Exchange Commission on August 15, 2019<BR>
                                              Registration No. 333-&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</P></B>

<P> &nbsp; </P>

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<B><P ALIGN="CENTER">UNITED STATES <BR>
                   SECURITIES AND EXCHANGE COMMISSION <BR>
                   Washington, D.C. 20549 </P></B>

<P ALIGN="CENTER">__________________________________________________________________________________________________________</P>


<B><P ALIGN="CENTER">FORM S-8 <BR>
                   REGISTRATION STATEMENT <BR>
<I>                   UNDER <BR>
                   THE SECURITIES ACT OF 1933 </B></I>&nbsp;</P>

<P ALIGN="CENTER">__________________________________________________________________________________________________________</P>

</FONT><B><FONT SIZE=4><P ALIGN="CENTER">Seelos Therapeutics, Inc. <BR>
</FONT><FONT SIZE=1>                   (Exact name of Registrant as specified in its charter) </P></B></FONT>

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<P ALIGN="CENTER">__________________________________________________________________________________________________________</P>


<P ALIGN="CENTER"><CENTER><TABLE CELLSPACING=0 BORDER=0 WIDTH=624>
<TR><TD WIDTH="51%" VALIGN="MIDDLE">&nbsp;</TD>
<TD WIDTH="1%" VALIGN="BOTTOM">&nbsp;</TD>
<TD WIDTH="48%" VALIGN="MIDDLE">&nbsp;</TD>
</TR>
<TR><TD WIDTH="51%" VALIGN="TOP">
<B><FONT SIZE=2><P ALIGN="CENTER">Nevada</B></FONT></TD>
<TD WIDTH="1%" VALIGN="BOTTOM">&nbsp;</TD>
<TD WIDTH="48%" VALIGN="TOP">
<B><FONT SIZE=2><P ALIGN="CENTER">87-0449967</B></FONT></TD>
</TR>
<TR><TD WIDTH="51%" VALIGN="TOP">
<B><FONT SIZE=2><P ALIGN="CENTER">(State or other jurisdiction of<BR>
                   incorporation or organization)</B></FONT></TD>
<TD WIDTH="1%" VALIGN="BOTTOM">
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="48%" VALIGN="TOP">
<B><FONT SIZE=2><P ALIGN="CENTER">(I.R.S. Employer<BR>
                   Identification No.)</B></FONT></TD>
</TR>
</TABLE>
</CENTER></P>

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<B><FONT SIZE=2><P ALIGN="CENTER">300 Park Avenue, 12th Floor<BR>
                   New York, NY 10022 <BR>
                   (Address of principal executive offices, including zip code) </P></B>

<P ALIGN="CENTER">__________________________________________________________________________________________________________</P>

<B><P ALIGN="CENTER">
               Seelos Therapeutics, Inc. 2019 Inducement Plan<BR>
                   (Full title of the plans) </P>


<P ALIGN="CENTER">Raj Mehra, Ph.D.<BR>
                  President, Chief Executive Officer and Chairman of the Board of Directors<BR>
                  Seelos Therapeutics, Inc. <BR>
                  300 Park Avenue, 12th Floor <BR>
                  New York, NY 10022<BR>
                  (646) 998-6475 <BR>
                  (Name, address and telephone number, including area code, of agent for service) </P></B>

<P ALIGN="CENTER">__________________________________________________________________________________________________________</P>


<B><I><P ALIGN="CENTER">Copies to: </P>
</I><P ALIGN="CENTER">Jeffrey T. Hartlin, Esq.<BR>
                   Paul Hastings LLP<BR>
                   1117 S. California Avenue<BR>
                   Palo Alto, California 94304 <BR>
                   (650) 320-1800 </P></B>

<P ALIGN="CENTER">__________________________________________________________________________________________________________</P>


<P>Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the
definitions of &quot;large accelerated filer,&quot; &quot;accelerated filer,&quot; &quot;smaller reporting company,&quot; and &quot;emerging growth company&quot; in Rule 12b-2 of the
Exchange Act. </P>


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<TR><TD WIDTH="19%" VALIGN="TOP">
<FONT SIZE=2><P>
Large accelerated filer  &nbsp;&nbsp; <FONT FACE="WINGDINGS">&#168; <FONT FACE="Times New Roman">
</FONT></TD>
<TD WIDTH="19%" VALIGN="TOP">
<FONT SIZE=2><P>
Accelerated filer &nbsp;&nbsp; <FONT FACE="WINGDINGS">&#168; <FONT FACE="Times New Roman">
</FONT></TD>
<TD WIDTH="24%" VALIGN="TOP">
<FONT SIZE=2><P>
Non-accelerated filer &nbsp;&nbsp; <FONT FACE="WINGDINGS">&#168; <FONT FACE="Times New Roman">
</FONT></TD>
<TD WIDTH="19%" VALIGN="TOP">
<FONT SIZE=2><P>
Smaller reporting company &nbsp;&nbsp; <FONT FACE="WINGDINGS">&#120; <FONT FACE="Times New Roman"></P>
</FONT></TD>
<TD WIDTH="19%" VALIGN="TOP">
<FONT SIZE=2><P>
Emerging growth company  &nbsp;&nbsp; <FONT FACE="WINGDINGS">&#168; <FONT FACE="Times New Roman"></P>
</FONT></TD>
</TR>
</TABLE>



<FONT SIZE=2><P>If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised
financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. </FONT><FONT FACE="Wingdings" SIZE=2> &#168; <FONT FACE="Times New Roman"></P>
<FONT SIZE=2>

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<B><P ALIGN="CENTER">CALCULATION OF REGISTRATION FEE </P></B>

<P ALIGN="CENTER"><CENTER><TABLE BORDER=0 CELLSPACING=1 BORDERCOLOR="#000000" WIDTH=85%>
<TR>
<TD STYLE="border-bottom: black 1.5pt solid" WIDTH="44%" VALIGN="BOTTOM" COLSPAN=2>
<B><FONT SIZE=2><P ALIGN="CENTER">Title of Securities to be Registered</B></FONT></TD>
<TD WIDTH="1%" VALIGN="BOTTOM">
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD STYLE="border-bottom: black 1.5pt solid" WIDTH="13%" VALIGN="BOTTOM">
<B><FONT SIZE=2><P ALIGN="CENTER">Amount<BR>
                  to be<BR>
                  Registered<SUP>(1)</B></SUP></FONT></TD>
<TD WIDTH="1%" VALIGN="BOTTOM">
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD STYLE="border-bottom: black 1.5pt solid" WIDTH="13%" VALIGN="BOTTOM">
<B><FONT SIZE=2><P ALIGN="CENTER">Proposed<BR>
                  Maximum<BR>
                  Offering Price<BR>
                  Per Share</B></FONT></TD>
<TD WIDTH="1%" VALIGN="BOTTOM">
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD STYLE="border-bottom: black 1.5pt solid" WIDTH="13%" VALIGN="BOTTOM">
<B><FONT SIZE=2><P ALIGN="CENTER">Proposed<BR>
                  Maximum<BR>
                  Aggregate<BR>
                  Offering&nbsp;Price</B></FONT></TD>
<TD WIDTH="1%" VALIGN="BOTTOM">
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD STYLE="border-bottom: black 1.5pt solid" WIDTH="13%" VALIGN="BOTTOM">
<B><FONT SIZE=2><P ALIGN="CENTER">Amount&nbsp;of<BR>
                  Registration&nbsp;Fee</B></FONT></TD>
</TR>
<TR><TD WIDTH="44%" VALIGN="MIDDLE" COLSPAN=2 HEIGHT=24><DIR>

<FONT SIZE=2><P>Common Stock, $0.001 par value per share, reserved for issuance pursuant to the Seelos Therapeutics, Inc. 2019 Inducement Plan</DIR>
</FONT></TD>
<TD WIDTH="1%" VALIGN="BOTTOM" HEIGHT=24>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="13%" VALIGN="MIDDLE" HEIGHT=24>
<FONT SIZE=2><P ALIGN="CENTER">902,715</FONT></TD>
<TD WIDTH="1%" VALIGN="MIDDLE" HEIGHT=24><P></P></TD>
<TD WIDTH="13%" VALIGN="MIDDLE" HEIGHT=24>
<FONT SIZE=2><P ALIGN="CENTER">$1.63<SUP>(2)</SUP></FONT></TD>
<TD WIDTH="1%" VALIGN="MIDDLE" HEIGHT=24><P></P></TD>
<TD WIDTH="13%" VALIGN="MIDDLE" HEIGHT=24>
<FONT SIZE=2><P ALIGN="CENTER">$1,471,425.45<SUP>(2)</SUP></FONT></TD>
<TD WIDTH="1%" VALIGN="MIDDLE" HEIGHT=24><P></P></TD>
<TD WIDTH="13%" VALIGN="MIDDLE" HEIGHT=24>
<FONT SIZE=2><P ALIGN="CENTER">$178.34</FONT></TD>
</TR>
<TR><TD WIDTH="44%" VALIGN="MIDDLE" COLSPAN=2 HEIGHT=24><DIR>

<FONT SIZE=2><P>Common Stock, $0.001 par value per share, issuable pursuant to outstanding options granted under the Seelos Therapeutics, Inc. 2019 Inducement Plan</DIR>
</FONT></TD>
<TD WIDTH="1%" VALIGN="BOTTOM" HEIGHT=24>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="13%" VALIGN="MIDDLE" HEIGHT=24>
<FONT SIZE=2><P ALIGN="CENTER">97,285</FONT></TD>
<TD WIDTH="1%" VALIGN="MIDDLE" HEIGHT=24><P></P></TD>
<TD WIDTH="13%" VALIGN="MIDDLE" HEIGHT=24>
<FONT SIZE=2><P ALIGN="CENTER">$1.60<SUP>(3)</SUP></FONT></TD>
<TD WIDTH="1%" VALIGN="MIDDLE" HEIGHT=24><P></P></TD>
<TD WIDTH="13%" VALIGN="MIDDLE" HEIGHT=24>
<FONT SIZE=2><P ALIGN="CENTER">$155,656.00<SUP>(3)</SUP></FONT></TD>
<TD WIDTH="1%" VALIGN="MIDDLE" HEIGHT=24><P></P></TD>
<TD WIDTH="13%" VALIGN="MIDDLE" HEIGHT=24>
<FONT SIZE=2><P ALIGN="CENTER">$18.86</FONT></TD>
</TR>
<TR><TD WIDTH="44%" VALIGN="MIDDLE" COLSPAN=2><DIR>

<FONT SIZE=2><P>TOTAL:</DIR>
</FONT></TD>
<TD WIDTH="1%" VALIGN="BOTTOM">
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="13%" VALIGN="MIDDLE">
<FONT SIZE=2><P ALIGN="CENTER">1,000,000</FONT></TD>
<TD WIDTH="1%" VALIGN="MIDDLE">&nbsp;</TD>
<TD WIDTH="13%" VALIGN="BOTTOM">
<FONT SIZE=2><P ALIGN="CENTER">- </FONT></TD>
<TD WIDTH="1%" VALIGN="MIDDLE">&nbsp;</TD>
<TD WIDTH="13%" VALIGN="MIDDLE">
<FONT SIZE=2><P ALIGN="CENTER">$1,627,081.45</FONT></TD>
<TD WIDTH="1%" VALIGN="MIDDLE">&nbsp;</TD>
<TD WIDTH="13%" VALIGN="MIDDLE">
<FONT SIZE=2><P ALIGN="CENTER">$197.20</FONT></TD>
</TR>
<TR><TD VALIGN="BOTTOM" COLSPAN=10>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
</TR>
<TR><TD VALIGN="BOTTOM" COLSPAN=10>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
</TR>
<TR><TD WIDTH="4%" VALIGN="TOP">
<FONT SIZE=2><P>(1)</FONT></TD>
<TD WIDTH="96%" VALIGN="TOP" COLSPAN=9>
<FONT SIZE=2><P ALIGN="JUSTIFY">Pursuant to Rule 416(a) of the Securities Act of 1933, as amended (the &quot;Securities Act&quot;), this Registration Statement on Form S-8 (the
&quot;Registration Statement&quot;) shall also cover any additional shares of common stock, $0.001 par value per share (the &quot;Common Stock&quot;), of the Registrant (defined below)
that become issuable under the Seelos Therapeutics, Inc. 2019 Inducement Plan (the &quot;2019 Plan&quot;), by reason of any stock dividend, stock split, recapitalization or other similar
transaction effected without receipt of consideration that increases the number of the Registrant's outstanding shares of Common Stock. </FONT></TD>
</TR>
<TR><TD WIDTH="4%" VALIGN="TOP">&nbsp;</TD>
<TD WIDTH="96%" VALIGN="TOP" COLSPAN=9>&nbsp;</TD>
</TR>
<TR><TD WIDTH="4%" VALIGN="TOP">
<FONT SIZE=2><P>(2)</FONT></TD>
<TD WIDTH="96%" VALIGN="TOP" COLSPAN=9>
<FONT SIZE=2><P ALIGN="JUSTIFY">Estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rules 457(c) and 457(h) of the Securities Act. The
proposed maximum aggregate offering price per share and the proposed maximum aggregate offering price with respect to these shares are calculated based on the average of the high and
low prices of the Common Stock as reported on the Nasdaq Capital Market on August 14, 2019, a date within five business days prior to the filing of this Registration Statement.</P>
</FONT></TD>
</TR>
<TR><TD WIDTH="4%" VALIGN="TOP">&nbsp;</TD>
<TD WIDTH="96%" VALIGN="TOP" COLSPAN=9>&nbsp;</TD>
</TR>
<TR><TD WIDTH="4%" VALIGN="TOP">
<FONT SIZE=2><P>(3)</FONT></TD>
<TD WIDTH="96%" VALIGN="TOP" COLSPAN=9>
<FONT SIZE=2><P ALIGN="JUSTIFY">Estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rule 457(h) of the Securities Act. The proposed maximum
offering price per share and the proposed maximum aggregate offering price are calculated based on $1.60 per share, which is the exercise price per share for the options issued and
outstanding under the 2019 Plan.</FONT></TD>
</TR>
<TR><TD WIDTH="4%" VALIGN="TOP">&nbsp;</TD>
<TD WIDTH="96%" VALIGN="TOP" COLSPAN=9>&nbsp;</TD>
</TR>
</TABLE>
</CENTER></P>

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<P style="PAGE-BREAK-BEFORE: always" align=left>

<B><P ALIGN="CENTER">EXPLANATORY NOTE </P>
</B><P ALIGN="JUSTIFY">Seelos Therapeutics, Inc. (the &quot;Registrant&quot;) has prepared this registration statement (this &quot;Registration Statement&quot;) in accordance with the
requirements of Form S-8 under the Securities Act to register 1,000,000 shares of Common Stock reserved for issuance under the 2019 Plan to new employees hired by the Registrant or its
subsidiaries.</P>

<B><P ALIGN="CENTER">PART I</P>
<P ALIGN="CENTER">INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS </P>
</B><P ALIGN="JUSTIFY">The document(s) containing the information specified in Part I will be sent or given to employees as specified by Rule 428(b)(1) of the Securities Act. Such
documents are not being filed with the Securities and Exchange Commission (the &quot;Commission&quot;) either as part of this Registration Statement or as prospectuses or prospectus
supplements pursuant to Rule 424 of the Securities Act. Such documents and the documents incorporated by reference in this Registration Statement pursuant to Item 3 of Part II hereof, taken
together, constitute a prospectus that meets the requirements of Section 10(a) of the Securities Act.</P>

<B><P ALIGN="CENTER">PART II</P>
<P ALIGN="CENTER">INFORMATION REQUIRED IN THE REGISTRATION STATEMENT </P>
<P>Item&nbsp;3. Incorporation of Documents by Reference. </P>
</B><P ALIGN="JUSTIFY">The following documents filed by the Registrant with the Commission are hereby incorporated by reference into this Registration Statement: </P>

<P ALIGN="JUSTIFY">&nbsp;</P>

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<TR><TD WIDTH="4%" VALIGN="MIDDLE">
<FONT SIZE=2><P ALIGN="JUSTIFY">&nbsp;</FONT></TD>
<TD WIDTH="4%" VALIGN="TOP">
<FONT SIZE=2><P ALIGN="JUSTIFY">(a)</FONT></TD>
<TD WIDTH="92%" VALIGN="TOP">
<P ALIGN="JUSTIFY"><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000113626119000121/body10k.htm"><FONT SIZE=2>The Registrant's Annual Report on Form 10-K for
the fiscal year ended December 31, 2018, filed with the Commission on March 28, 2019</FONT></A><FONT SIZE=2>;</FONT></TD>
</TR>
<TR><TD WIDTH="4%" VALIGN="MIDDLE">&nbsp;</TD>
<TD WIDTH="4%" VALIGN="TOP">&nbsp;</TD>
<TD WIDTH="92%" VALIGN="TOP">&nbsp;</TD>
</TR>
<TR><TD WIDTH="4%" VALIGN="MIDDLE">
<FONT SIZE=2><P ALIGN="JUSTIFY">&nbsp;</FONT></TD>
<TD WIDTH="4%" VALIGN="TOP">
<FONT SIZE=2><P ALIGN="JUSTIFY">(b)</FONT></TD>
<TD WIDTH="92%" VALIGN="TOP">
<FONT SIZE=2><P ALIGN="JUSTIFY">The Registrant's Quarterly Reports on Form 10-Q for the quarters ended (i) </FONT><A
HREF="http://www.sec.gov/Archives/edgar/data/1017491/000113626119000166/body10q.htm"><FONT SIZE=2>March 31, 2019, filed with the Commission on May 21,
2019</FONT></A><FONT SIZE=2>, and (ii) </FONT><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000113626119000209/body10q.htm"><FONT SIZE=2>June 30, 2019,
filed with the Commission on August 1, 2019</FONT></A><FONT SIZE=2>;</FONT></TD>
</TR>
<TR><TD WIDTH="4%" VALIGN="MIDDLE">&nbsp;</TD>
<TD WIDTH="4%" VALIGN="TOP">&nbsp;</TD>
<TD WIDTH="92%" VALIGN="TOP">&nbsp;</TD>
</TR>
<TR><TD WIDTH="4%" VALIGN="MIDDLE">&nbsp;</TD>
<TD WIDTH="4%" VALIGN="TOP">
<FONT SIZE=2><P ALIGN="JUSTIFY">(c)</FONT></TD>
<TD WIDTH="92%" VALIGN="TOP">
<P ALIGN="JUSTIFY"><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000114036119007041/nc10000977x1_def14a.htm"><FONT SIZE=2>The Registrant's Definitive Proxy
Statement on Schedule 14A filed with the Commission on April 12, 2019</FONT></A><FONT SIZE=2>;</FONT></TD>
</TR>
<TR><TD WIDTH="4%" VALIGN="MIDDLE">&nbsp;</TD>
<TD WIDTH="4%" VALIGN="TOP">&nbsp;</TD>
<TD WIDTH="92%" VALIGN="TOP">&nbsp;</TD>
</TR>
<TR><TD WIDTH="4%" VALIGN="MIDDLE">&nbsp;</TD>
<TD WIDTH="4%" VALIGN="TOP">
<FONT SIZE=2><P ALIGN="JUSTIFY">(d)</FONT></TD>
<TD WIDTH="92%" VALIGN="TOP">
<FONT SIZE=2><P ALIGN="JUSTIFY">The Registrant's Current Reports on Form 8-K filed with the Commission on (i) </FONT><A
HREF="http://www.sec.gov/Archives/edgar/data/1017491/000114036119000397/form8k.htm"><FONT SIZE=2>January 4, 2019</FONT></A><FONT SIZE=2>, (ii) </FONT><A
HREF="http://www.sec.gov/Archives/edgar/data/1017491/000114036119001204/form8k.htm"><FONT SIZE=2>January 16, 2019</FONT></A><FONT SIZE=2>, (iii) </FONT><A
HREF="http://www.sec.gov/Archives/edgar/data/1017491/000114036119001465/form8k.htm"><FONT SIZE=2>January 24, 2019 at 8:05 a.m. Eastern Time</FONT></A><FONT SIZE=2>,
(iv) </FONT><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000114036119001467/form8k.htm"><FONT SIZE=2>January 24, 2019 at 8:06 a.m. Eastern
Time</FONT></A><FONT SIZE=2>, (v) </FONT><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000113626119000038/body8k.htm"><FONT SIZE=2>February 6,
2019</FONT></A><FONT SIZE=2> and (vi) </FONT><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000113626119000068/body8k.htm"><FONT SIZE=2>February 19,
2019</FONT></A><FONT SIZE=2>; (vii) </FONT><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000113626119000099/body8k.htm"><FONT SIZE=2>March 8,
2019</FONT></A><FONT SIZE=2>; (viii) </FONT><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000113626119000116/body8k.htm"><FONT SIZE=2>March 26,
2019</FONT></A><FONT SIZE=2>; (ix) </FONT><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000113626119000126/body8k.htm"><FONT SIZE=2>April 8,
2019</FONT></A><FONT SIZE=2>; (x) </FONT><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000113626119000152/body8k.htm"><FONT SIZE=2>May 13,
2019</FONT></A><FONT SIZE=2>; (xi) </FONT><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000113626119000178/body8k.htm"><FONT SIZE=2>June 18,
2019</FONT></A><FONT SIZE=2>; (xii) </FONT><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000113626119000181/body8k.htm"><FONT SIZE=2>June 27, 2019</FONT></A><FONT SIZE=2>;
and (xiii) </FONT><A HREF=" http://www.sec.gov/Archives/edgar/data/1017491/000113626119000215/body8k.htm"><FONT SIZE=2>August 14, 2019</FONT></A><FONT SIZE=2>;
</FONT></TD>
</TR>
<TR><TD WIDTH="4%" VALIGN="MIDDLE">&nbsp;</TD>
<TD WIDTH="4%" VALIGN="TOP">&nbsp;</TD>
<TD WIDTH="92%" VALIGN="TOP">&nbsp;</TD>
</TR>
<TR><TD WIDTH="4%" VALIGN="MIDDLE">
<FONT SIZE=2><P ALIGN="JUSTIFY">&nbsp;</FONT></TD>
<TD WIDTH="4%" VALIGN="TOP">
<FONT SIZE=2><P ALIGN="JUSTIFY">(e)</FONT></TD>
<TD WIDTH="92%" VALIGN="TOP">
<FONT SIZE=2><P ALIGN="JUSTIFY">The Registrant's Current Reports on Form 8-K/A filed with the Commission on (i) </FONT><A
HREF="http://www.sec.gov/Archives/edgar/data/1017491/000113626119000017/body8ka.htm"><FONT SIZE=2>January 30, 2019</FONT></A><FONT SIZE=2> and (ii) </FONT><A
HREF="http://www.sec.gov/Archives/edgar/data/1017491/000113626119000089/body8ka.htm"><FONT SIZE=2>March 1, 2019</FONT></A><FONT SIZE=2>; and</FONT></TD>
</TR>
<TR><TD WIDTH="4%" VALIGN="MIDDLE">&nbsp;</TD>
<TD WIDTH="4%" VALIGN="TOP">&nbsp;</TD>
<TD WIDTH="92%" VALIGN="TOP">&nbsp;</TD>
</TR>
<TR><TD WIDTH="4%" VALIGN="MIDDLE">
<FONT SIZE=2><P ALIGN="JUSTIFY">&nbsp;</FONT></TD>
<TD WIDTH="4%" VALIGN="TOP">
<FONT SIZE=2><P ALIGN="JUSTIFY">(f)</FONT></TD>
<TD WIDTH="92%" VALIGN="TOP">
<FONT SIZE=2><P ALIGN="JUSTIFY">The description of the Registrant's common stock set forth in the Registrant's </FONT><A
HREF="http://www.sec.gov/Archives/edgar/data/1017491/000100547700002994/0001005477-00-002994.txt"><FONT SIZE=2>Registration Statement on Form 8-A (File No. 000-22245), filed
with the Commission on April 10, 2000</FONT></A><FONT SIZE=2>, including any amendments or reports filed for the purpose of updating such description.</FONT></TD>
</TR>
</TABLE>


<FONT SIZE=2><P ALIGN="JUSTIFY">&nbsp;All other reports and other documents subsequently filed by the Registrant pursuant to Sections 13(a), 13(c), 14 or 15(d) of the Securities
Exchange Act of 1934, as amended (the &quot;Exchange Act&quot;), prior to the filing of a post-effective amendment which indicates that all securities offered hereby have been sold or which
deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference into this Registration Statement and to be a part of this Registration Statement from the date
of the filing of such reports and documents, except as to any portion of any future annual or quarterly report to shareholders or document or current report furnished under Items 2.02 or 7.01 of
Form 8-K that is not deemed filed under such provisions.</P>


<HR WIDTH="100%">
<P style="PAGE-BREAK-BEFORE: always" align=left>


<P ALIGN="JUSTIFY">For the purposes of this Registration Statement, any statement contained in a document incorporated or deemed to be incorporated by reference herein shall be
deemed to be modified or superseded to the extent that a statement contained herein or in any other subsequently filed document that also is or is deemed to be incorporated by reference
herein modifies or supersedes such statement. Any such statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this
Registration Statement.</P>
<P ALIGN="JUSTIFY">You should rely only on the information provided or incorporated by reference in this Registration Statement or any related prospectus. The Registrant has not
authorized anyone to provide you with different information. You should not assume that the information in this Registration Statement or any related prospectus is accurate as of any date other
than the date on the front of the document.</P>
<P ALIGN="JUSTIFY">You may contact the Registrant in writing or orally to request copies of the above-referenced filings, without charge (excluding exhibits to such documents unless such
exhibits are specifically incorporated by reference into the information incorporated by reference into this Registration Statement). Requests for such information should be directed to:</P>

<P ALIGN="CENTER">Seelos Therapeutics, Inc.<BR>
                  300 Park Avenue, 12th Floor<BR>
                  New York, NY 10022<BR>
                   (646) 998-6475</P>

<B><P>Item&nbsp;4. Description of Securities. </P>
</B><P>Not applicable. </P>

<B><P>Item&nbsp;5. Interests of Named Experts and Counsel. </P>
</B><P ALIGN="JUSTIFY">Not applicable. </P>

<B><P>Item&nbsp;6. Indemnification of Directors and Officers. </P>
</B><P ALIGN="JUSTIFY">The Registrant's officers and directors are indemnified under Nevada law, the Registrant's Amended and Restated Articles of Incorporation, as amended, and its
Fourth Amended and Restated Bylaws, as amended, against certain liabilities. The Registrant's Amended and Restated Articles of Incorporation, as amended, require the Registrant to
indemnify its directors and officers to the fullest extent permitted by the laws of the State of Nevada in effect from time to time.</P>
<P ALIGN="JUSTIFY">Pursuant to its Amended and Restated Articles of Incorporation, as amended, none of the Registrant's directors or officers shall be personally liable to the Registrant or
its stockholders for damages for breach of fiduciary duty as a director or officer, except for (1) acts or omissions which involve intentional misconduct, fraud or a knowing violation of law, or (2)
the payment of dividends in violation of the applicable statutes of Nevada. Further, the Registrant's Amended and Restated Articles of Incorporation, as amended, provide that if Nevada law is
amended to authorize corporate action further eliminating or limiting the personal liability of directors or officers, the liability of a director or officer of the corporation shall be eliminated or limited
to the fullest extent permitted by Nevada law, as so amended from time to time. However, Nevada Revised Statutes 78.138 currently provides that, except as otherwise provided in the Nevada
Revised Statutes, a director or officer shall not be individually liable to the Registrant or its stockholders or creditors for any damages as a result of any act or failure to act in his or her capacity
as a director or officer unless it is proven that (i) the presumption established by Nevada Revised Statutes 78.138(3) has been rebutted, (ii) the director's or officer's acts or omissions
constituted a breach of his or her fiduciary duties as a director or officer, and (iii) such breach involved intentional misconduct, fraud or a knowing violation of the law.</P>

<P ALIGN="JUSTIFY">Pursuant to the Registrant's Amended and Restated Articles of Incorporation, as amended, it shall indemnify any person who was or is a party or is threatened to be
made a party to any threatened, pending or completed action, suit or proceeding, by reason of the fact that he or she is or was or has agreed to become a director or officer of the Registrant or
is serving at the Registrant's request as a director or officer of another entity or enterprise or by reason


<HR WIDTH="100%">
<P style="PAGE-BREAK-BEFORE: always" align=left>

<P ALIGN="JUSTIFY">
of actions alleged to have been taken or omitted in such capacity or in any other capacity
while serving as a director or officer, to the fullest extent permitted by applicable law, against any and all loss, liability and expenses, including attorneys' fees, costs, damages, judgments, fines,
amounts paid in settlement, and ERISA excise taxes or penalties, actually and reasonably incurred by such person in connection with such action, suit or proceeding, including any appeal. This
right to indemnification shall continue for any person who has ceased to be a director or officer and shall inure to the benefit of his or her heirs, next of kin, executors, administrators and legal
representatives.</P>
<P ALIGN="JUSTIFY">The Registrant's Amended and Restated Articles of Incorporation, as amended, also provide that it shall pay the expenses of directors and officers incurred as a party to
any threatened, pending or completed action, suit or proceeding, as they are incurred and in advance of the final disposition of the action, suit or proceeding, but, if applicable law so requires,
only upon receipt by the Registrant of an undertaking from the director or officer to repay the advanced amounts in the event it is ultimately determined by a final decision, order or decree of a
court of competent jurisdiction that the director or officer is not entitled to be indemnified for such expenses.</P>
<P ALIGN="JUSTIFY">The Registrant's Fourth Amended and Restated Bylaws, as amended, provide that the Registrant shall indemnify and hold harmless, to the fullest extent permitted by
the laws of the State of Nevada, each director or officer of the corporation who was or is a party to, or is threatened to be made a party to, or is otherwise involved in, any threatened, pending,
or completed action, suit or proceeding (whether civil, criminal, administrative or investigative, and including, without limitation, an action, suit or proceeding by or in the right of the corporation),
by reason of the fact that he or she is or was a director or officer of the corporation or is or was serving in any capacity at the request of the corporation as a director, officer, employee, agent,
partner, member, manager or fiduciary of, or in any other capacity for, another corporation or any partnership, joint venture, limited liability company, trust or other enterprise. Such
indemnification shall be against all expense, liability and loss (including, without limitation, attorneys' fees, judgments, fines, taxes, penalties and amounts paid or to be paid in settlement)
reasonably incurred or suffered by such director or officer in connection with any such action, suit or proceeding; provided that such director or officer either is not liable pursuant to Nevada
Revised Statutes 78.138 or acted in good faith and in a manner he or she reasonably believed to be in or not opposed to the best interests of the corporation, and with respect to any such
action, suit or proceeding that is criminal in nature, had no reasonable cause to believe that his or her conduct was unlawful. No such indemnification shall be made to or on behalf of any such
director or officer if a final adjudication establishes that his or her acts or omissions involved intentional misconduct, fraud or a knowing violation of law and was material to the cause of action,
or for any expenses of such director or officer incurred in his or her capacity as a stockholder. The Fourth Amended and Restated Bylaws, as amended, also require that the expenses of such
directors and officers must be paid by the corporation (or through insurance maintained, or other financial arrangements made, by the corporation) as such expenses are incurred and in
advance of the final disposition of such action, suit or proceeding, upon receipt of an undertaking by or on behalf of such director or officer to repay the amount if it is ultimately determined by a
court of competent jurisdiction that he or she is not entitled to be indemnified by the corporation. Any indemnification of directors and officers under the Fourth Amended and Restated Bylaws,
as amended, shall inure to the benefit of their respective heirs, executors and administrators.</P>
<P ALIGN="JUSTIFY">Section 78.7502 of the Nevada Revised Statutes permits a corporation to indemnify a present or former director, officer, employee or agent of the corporation, or of
another entity or enterprise for which such person is or was serving in such capacity at the request of the corporation, who was or is a party or is threatened to be made a party to any
threatened, pending or completed action, suit or proceeding, except an action by or in the right of the corporation, against expenses, including attorneys' fees, judgments, fines and amounts
paid in settlement actually and reasonably incurred in connection therewith, arising by reason of such person's service in such capacity if such person (i) is not liable pursuant to Section 78.138
of the Nevada Revised Statutes, or (ii) acted in good faith and in a manner which he or she reasonably believed to be in or not opposed to the best interests of the corporation and, with respect
to a criminal action or proceeding, had no reasonable cause to believe his or her conduct was unlawful. In the case of actions brought by or in the right of the corporation, however, no
indemnification may be made for any claim, issue or matter as to which such person has been adjudged by a court of competent jurisdiction, after exhaustion of all appeals therefrom, to be
liable to the corporation or for amounts paid in settlement to the corporation, unless and only to the extent that the court in which the action or suit was brought or other court of competent
jurisdiction determines upon application that in view of all the circumstances of the case, such person is fairly and reasonably entitled to indemnity for such expenses as the court deems proper.</P>


<HR WIDTH="100%">
<P style="PAGE-BREAK-BEFORE: always" align=left>

<P ALIGN="JUSTIFY">Section 78.751 of the Nevada Revised Statutes permits any discretionary indemnification under Section 78.7502 of the Nevada Revised Statutes, unless ordered by a
court or advanced to a director or officer by the corporation in accordance with the Nevada Revised Statutes, to be made by a corporation only as authorized in each specific case upon a
determination that indemnification of the director, officer, employee or agent is proper in the circumstances. Such determination must be made (1) by the stockholders, (2) by the board of
directors by majority vote of a quorum consisting of directors who were not parties to the action, suit or proceeding, (3) if a majority vote of a quorum consisting of directors who were not parties
to the action, suit or proceeding so orders, by independent legal counsel in a written opinion, or (4) if a quorum consisting of directors who were not parties to the action, suit or proceeding
cannot be obtained, by independent legal counsel in a written opinion.</P>

<P ALIGN="JUSTIFY">The Registrant maintains a general liability insurance policy that covers certain liabilities of directors and officers of the corporation arising out of claims based on acts or
omissions in their capacities as directors or officers.</P>
<P ALIGN="JUSTIFY">See also the undertakings set out in response to Item 9 herein.</P>

<B><P>Item&nbsp;7. Exemption from Registration Claimed. </P>
</B><P ALIGN="JUSTIFY">Not applicable. </P>

<B><P>Item&nbsp;8.&nbsp;Exhibits. </P></B>

<P> &nbsp; </P>

<TABLE BORDER=0 CELLSPACING=0 CELLPADDING=0 WIDTH=95%>
<TR>
<TD STYLE="border-bottom: black 1.5pt solid" WIDTH="5%" VALIGN="TOP" COLSPAN=2>
<B><FONT SIZE=1><P>Exhibit<BR>
Number</B></FONT></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD STYLE="border-bottom: black 1.5pt solid" WIDTH="94%" VALIGN="TOP">
<B><FONT SIZE=1><P ALIGN="CENTER">Description of Document</B></FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="95%" VALIGN="MIDDLE" COLSPAN=3><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<P><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/0001005477-97-000778.txt"><U><FONT SIZE=2 COLOR="#0000ff">3.1</U></FONT></A></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Amended and Restated Articles of Incorporation of the Registrant (incorporated herein by reference to Exhibit 2.1 to the Registrant's Registration Statement on Form 10-SB filed
with the Securities and Exchange Commission on March 14, 1997).</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="95%" VALIGN="MIDDLE" COLSPAN=4><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<P><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000095013603000741/file002.txt"><U><FONT SIZE=2 COLOR="#0000ff">3.2</U></FONT></A></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Certificate of Amendment to Articles of Incorporation of the Registrant, dated June 22, 2000 (incorporated herein by reference to Exhibit 3.2 to the Registrant's Form 10-K
filed with the Securities and Exchange Commission on March 31, 2003).</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="95%" VALIGN="MIDDLE" COLSPAN=4><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<P><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000114420406010273/v037542_ex3-4.htm"><U><FONT SIZE=2 COLOR="#0000ff">3.3</U></FONT></A></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Certificate of Amendment to Articles of Incorporation of the Registrant, dated June 14, 2005 (incorporated herein by reference to Exhibit 3.4 to the Registrant's Form 10-K
filed with the Securities and Exchange Commission on March 16, 2006).</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="95%" VALIGN="MIDDLE" COLSPAN=4><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<P><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000114420410017441/v178249_ex3-6.htm"><U><FONT SIZE=2 COLOR="#0000ff">3.4</U></FONT></A></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Certificate of Amendment to Amended and Restated Articles of Incorporation of the Registrant, dated March 3, 2010 (incorporated herein by reference to Exhibit 3.6 to the
Registrant's Annual Report on Form 10-K filed with the Securities and Exchange Commission on March 31, 2010).</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="95%" VALIGN="MIDDLE" COLSPAN=4><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<P><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000114420410017441/v178249_ex3-7.htm"><U><FONT SIZE=2 COLOR="#0000ff">3.5</U></FONT></A></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Certificate of Correction to Certificate of Amendment to Amended and Restated Articles of Incorporation of the Registrant, dated March 3, 2010 (incorporated herein by
reference to Exhibit 3.7 to the Registrant's Annual Report on Form 10-K filed with the Securities and Exchange Commission on March 31, 2010).</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="95%" VALIGN="MIDDLE" COLSPAN=4><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<P><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000114420411016743/v215636_ex3-1.htm"><U><FONT SIZE=2 COLOR="#0000ff">3.6</U></FONT></A></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Certificate of Designation for Series D Junior-Participating Cumulative Preferred Stock (incorporated herein by reference to Exhibit 3.1 to the Registrant's Current Report
on Form 8-A12G filed with the Securities and Exchange Commission on March 24, 2011).</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<P><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000114420410034002/v188471_ex3-1.htm"><U><FONT SIZE=2 COLOR="#0000ff">3.7</U></FONT></A></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Certificate of Change filed with the Nevada Secretary of State (incorporated herein by reference to Exhibit 3.1 to the Registrant's Current Report on Form 8-K filed with the
Securities and Exchange Commission on June 17, 2010).</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
</TR>
</TABLE>


<HR WIDTH="100%">
<P style="PAGE-BREAK-BEFORE: always" align=left>

<TABLE BORDER=0 CELLSPACING=0 CELLPADDING=0 WIDTH=95%>
<TR>
<TD STYLE="border-bottom: black 1.5pt solid" WIDTH="5%" VALIGN="TOP" COLSPAN=2>
<B><FONT SIZE=1><P>Exhibit<BR>
Number</B></FONT></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD STYLE="border-bottom: black 1.5pt solid" WIDTH="94%" VALIGN="TOP">
<B><FONT SIZE=1><P ALIGN="CENTER">Description of Document</B></FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<P><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000114420410048909/v196361_ex3-1.htm"><U><FONT SIZE=2 COLOR="#0000ff">3.8</U></FONT></A></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Certificate of Amendment to Amended and Restated Articles of Incorporation of the Registrant, dated September 10, 2010 (incorporated herein by reference to Exhibit 3.1
to the Registrant's Current Report on Form 8-K filed with the Securities and Exchange Commission on September 10, 2010).</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<P><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000119312513224446/d539505dex31.htm"><U><FONT SIZE=2 COLOR="#0000ff">3.9</U></FONT></A></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Certificate of Withdrawal of Series D Junior Participating Cumulative Preferred Stock, dated May&nbsp;15, 2013 (incorporated herein by reference to Exhibit 3.1 to the
Registrant's Current Report on Form 8-K filed with the Securities and Exchange Commission on May&nbsp;16, 2013).</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<P><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000101749116000227/exhibit31to8-konreversesto.htm"><U><FONT SIZE=2
COLOR="#0000ff">3.10</U></FONT></A></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Certificate of Change filed with the Nevada Secretary of State (incorporated herein by reference to Exhibit 3.1 to the Registrant's Form 8-K filed with the Securities and
Exchange Commission on October 25, 2016).</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<P><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000101749117000091/apri63017ex310.htm"><FONT SIZE=2>3.11</FONT></A></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Certificate of Amendment filed with the Nevada Secretary of State (incorporated herein by reference to Exhibit 3.10 to the Registrant's Quarterly Report on Form 10-Q filed
with the Securities and Exchange Commission on August 2, 2017).</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<P><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000101749118000075/apri63018ex312.htm"><FONT SIZE=2>3.12</FONT></A></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Certificate of Amendment filed with the Nevada Secretary of State (incorporated herein by reference to Exhibit 3.12 to the Registrant's Quarterly Report on Form 10-Q filed
with the Securities and Exchange Commission on August 9, 2018).</P>
</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<P><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000114036119001465/ex3_1.htm"><FONT SIZE=2>3.13</FONT></A></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Certificate of Amendment related to the Share Increase Amendment, filed January 23, 2019 (incorporated herein by reference to Exhibit 3.1 to the Registrant's Current
Report on Form 8-K filed with the Securities and Exchange Commission on January 24, 2019 at 8:05 Eastern Time).</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<P><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000114036119001465/ex3_2.htm"><FONT SIZE=2>3.14</FONT></A></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Certificate of Amendment related to the Name Change, filed January 23, 2019 (incorporated herein by reference to Exhibit 3.2 to the Registrant's Current Report on Form
8-K filed with the Securities and Exchange Commission on January 24, 2019 at 8:05 Eastern Time).</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<P><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000114036119001465/ex3_3.htm"><FONT SIZE=2>3.15</FONT></A></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Amended and Restated Bylaws, dated January 24, 2019 (incorporated herein by reference to Exhibit 3.3 to the Registrant's Current Report on Form 8-K filed with the
Securities and Exchange Commission on January 24, 2019 at 8:05 Eastern Time).</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<P><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000114420411016740/v215638_ex4-1.htm"><U><FONT SIZE=2 COLOR="#0000ff">4.1</U></FONT></A></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Form of Common Stock Certificate (incorporated herein by reference to Exhibit 4.1 to the Registrant's Current Report on Form 8-K filed with the Securities and Exchange
Commission on March 24, 2011).</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<P><A HREF="http://www.sec.gov/Archives/edgar/data/1017491/000113626119000215/exh10-1.htm"><U><FONT SIZE=2 COLOR="#0000ff">4.2</U></FONT></A></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Seelos Therapeutics, Inc. 2019 Inducement Plan (incorporated herein by reference to Exhibit 10.1 to the Registrant's Current Report on Form 8-K filed with the Securities
and Exchange Commission on August 14, 2019). </FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<FONT SIZE=2><P><A HREF="exh4-3.htm">4.3</A></FONT></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Form of Stock Option Agreement under the Seelos Therapeutics, Inc. 2019 Inducement Plan.</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<FONT SIZE=2><P><A HREF="exh5-1.htm">5.1</A></FONT></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Opinion of Brownstein Hyatt Farber Schreck, LLP.</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<FONT SIZE=2><P><A HREF="exh23-1.htm">23.1</A></FONT></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Consent of BDO USA LLP, Independent Registered Public Accounting Firm.</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<FONT SIZE=2><P><A HREF="exh23-2.htm">23.2</A></FONT></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Consent of KPMG LLP, Independent Registered Public Accounting Firm.</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<FONT SIZE=2><P><A HREF="exh5-1.htm">23.3</A></FONT></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Consent of Brownstein Hyatt Farber Schreck, LLP (included in Exhibit 5.1).</FONT></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP"><P>&nbsp;</P></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
</TR>
<TR><TD WIDTH="5%" VALIGN="TOP">
<FONT SIZE=2><P>24.1</FONT></TD>
<TD WIDTH="1%" VALIGN="TOP" COLSPAN=2><P>&nbsp;</P></TD>
<TD WIDTH="94%" VALIGN="TOP" COLSPAN=2>
<FONT SIZE=2><P>Power of Attorney (included on signature page).</FONT></TD>
</TR>
</TABLE>



<HR WIDTH="100%">
<P style="PAGE-BREAK-BEFORE: always" align=left>

<B><P>Item&nbsp;9. Undertakings. </P>
</B><P ALIGN="JUSTIFY">A. The undersigned Registrant hereby undertakes:</P><DIR>
<DIR>

<P ALIGN="JUSTIFY">(1) To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:</P><DIR>
<DIR>

<P ALIGN="JUSTIFY">(i) To include any prospectus required by Section 10(a)(3) of the Securities Act;</P>
<P ALIGN="JUSTIFY">(ii) To reflect in the prospectus any facts or events arising after the effective date of the registration statement (or the most recent post-effective amendment thereof)
which, individually or in the aggregate, represent a fundamental change in the information set forth in the registration statement. Notwithstanding the foregoing, any increase or decrease in
volume of securities offered (if the total dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum
offering range may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the changes in volume and price represent no more than a 20
percent change in the maximum aggregate offering price set forth in the &quot;Calculation of Registration Fee&quot; table in the effective registration statement; and</P>
<P ALIGN="JUSTIFY">(iii) To include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement or any material change to such
information in the Registration Statement.</P></DIR>
</DIR>

<I><P ALIGN="JUSTIFY">Provided, however</I>, that paragraphs (A)(1)(i) and (A)(1)(ii) do not apply if the information required to be included in a post-effective amendment by those
paragraphs is contained in periodic reports filed with or furnished to the Commission by the Registrant pursuant to Section 13 or Section 15(d) of the Exchange Act that are incorporated by
reference in this Registration Statement.</P>
<P ALIGN="JUSTIFY">(2) That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement
relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.</P>
<P ALIGN="JUSTIFY">(3) To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the
offering.</P></DIR>
</DIR>

<P ALIGN="JUSTIFY">B. The undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the Registrant's annual report
pursuant to Section 13(a) or Section 15(d) of the Exchange Act (and, where applicable, each filing of an employee benefit plan's annual report pursuant to Section 15(d) of the Exchange Act)
that is incorporated by reference in the Registration Statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at
that time shall be deemed to be the initial bona fide offering thereof.</P>

<P ALIGN="JUSTIFY">C. Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the Registrant pursuant to the
foregoing provisions, or otherwise, the Registrant has been advised that in the opinion of the Commission such indemnification is against public policy as expressed in the Securities Act and is,
therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer or
controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being
registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such
indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.</P>

<P> &nbsp; </P>


<HR WIDTH="100%">
<P style="PAGE-BREAK-BEFORE: always" align=left>

<B><P ALIGN="CENTER">SIGNATURES</P></B>

<P>Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of New York,
State of New York, on August 15, 2019. </P>

<TABLE BORDER=0 CELLSPACING=1 BORDERCOLOR="#000000" WIDTH=95%>
<TR><TD WIDTH="48%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="42%" VALIGN="TOP" COLSPAN=2 HEIGHT=16>
<B><FONT SIZE=2><P>SEELOS THERAPEUTICS, INC.</B></FONT></TD>
<TD WIDTH="10%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
</TR>
<TR><TD WIDTH="48%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="6%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="36%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="10%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
</TR>
<TR><TD WIDTH="48%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="6%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>By:</FONT></TD>
<TD STYLE="border-bottom: black 1.5pt solid" WIDTH="36%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P><A NAME="tab2"></A>/s/ Raj Mehra, Ph.D.</FONT></TD>
<TD WIDTH="10%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
</TR>
<TR><TD WIDTH="48%" VALIGN="TOP" HEIGHT=33>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="6%" VALIGN="TOP" HEIGHT=33>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="36%" VALIGN="TOP" HEIGHT=33>
<FONT SIZE=2><P>&nbsp;&nbsp;&nbsp;Raj Mehra, Ph.D.<BR>
<I> &nbsp;&nbsp;&nbsp;&nbsp;President and Chief Executive Officer</I></FONT></TD>
<TD WIDTH="10%" VALIGN="TOP" HEIGHT=33>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
</TR>
</TABLE>

<B><FONT SIZE=2><P ALIGN="CENTER">POWER OF ATTORNEY </P>
<P ALIGN="JUSTIFY">KNOW ALL PERSONS BY THESE PRESENTS</B>, that each person whose signature appears below constitutes and appoints Raj Mehra, Ph.D. his or her true and
lawful attorney-in-fact and agent, with full power of substitution and resubstitution, for him or her and in his or her name, place and stead, in any and all capacities, to sign any and all
amendments (including post-effective amendments) to this Registration Statement, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the
Securities and Exchange Commission, granting unto said attorney-in-fact and agent full power and authority to do and perform each and every act and thing requisite and necessary to be done
in connection therewith, as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorney-in-fact and agent or his substitutes or
substitute, may lawfully do or cause to be done by virtue hereof.</P>
<P>Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed by the following persons in the capacities and on the dates indicated.</P>


<TABLE BORDER=0 CELLSPACING=1 BORDERCOLOR="#000000" WIDTH=95%>
<TR><TD WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<B><FONT SIZE=2><P ALIGN="CENTER">Signature</B></FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<B><FONT SIZE=2><P ALIGN="CENTER">Title</B></FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="17%" VALIGN="TOP" HEIGHT=16>
<B><FONT SIZE=2><P ALIGN="CENTER">Date</B></FONT></TD>
</TR>
<TR><TD WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="17%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
</TR>
<TR>
<TD STYLE="border-bottom: black 1.5pt solid" WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P ALIGN="CENTER">/s/ Raj Mehra, Ph.D.</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P ALIGN="CENTER">President, Chief Executive Officer, Chairman of the Board and Interim Chief Financial Officer</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="17%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P ALIGN="CENTER">August 15, 2019</FONT></TD>
</TR>
<TR><TD WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P ALIGN="CENTER">Raj Mehra, Ph.D.</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<I><FONT SIZE=2><P ALIGN="CENTER">(Principal Executive Officer, Principal Financial and Accounting Officer)</I></FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="17%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
</TR>
<TR><TD WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="17%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
</TR>
<TR>
<TD STYLE="border-bottom: black 1.5pt solid" WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P ALIGN="CENTER">&nbsp;</P>
<P ALIGN="CENTER">/s/ Brian Lian, Ph.D.</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P ALIGN="CENTER">&nbsp;</P>
<P ALIGN="CENTER">Director</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="17%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P ALIGN="CENTER">&nbsp;</P>
<P ALIGN="CENTER">August 15, 2019</FONT></TD>
</TR>
<TR><TD WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P ALIGN="CENTER">Brian Lian, Ph.D.</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="17%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
</TR>
<TR><TD WIDTH="40%" VALIGN="TOP" HEIGHT=16><P></P></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16><P></P></TD>
<TD WIDTH="40%" VALIGN="TOP" HEIGHT=16><P></P></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16><P></P></TD>
<TD WIDTH="17%" VALIGN="TOP" HEIGHT=16><P></P></TD>
</TR>
<TR>
<TD STYLE="border-bottom: black 1.5pt solid" WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P ALIGN="CENTER">&nbsp;</P>
<P ALIGN="CENTER">/s/ Daniel J. O'Connor, J.D.</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P ALIGN="CENTER">&nbsp;</P>
<P ALIGN="CENTER">Director</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="17%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P ALIGN="CENTER">&nbsp;</P>
<P ALIGN="CENTER">August 15, 2019</FONT></TD>
</TR>
<TR><TD WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P ALIGN="CENTER">Daniel J. O'Connor, J.D.</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="17%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
</TR>
<TR><TD WIDTH="40%" VALIGN="TOP" HEIGHT=16><P></P></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16><P></P></TD>
<TD WIDTH="40%" VALIGN="TOP" HEIGHT=16><P></P></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16><P></P></TD>
<TD WIDTH="17%" VALIGN="TOP" HEIGHT=16><P></P></TD>
</TR>
<TR>
<TD STYLE="border-bottom: black 1.5pt solid" WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P ALIGN="CENTER">&nbsp;</P>
<P ALIGN="CENTER">/s/ Richard W. Pascoe</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P ALIGN="CENTER">&nbsp;</P>
<P ALIGN="CENTER">Director</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="17%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P ALIGN="CENTER">&nbsp;</P>
<P ALIGN="CENTER">August 15, 2019</FONT></TD>
</TR>
<TR><TD WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P ALIGN="CENTER">Richard W. Pascoe </FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="17%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
</TR>
<TR><TD WIDTH="40%" VALIGN="TOP">
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP"><P></P></TD>
<TD WIDTH="40%" VALIGN="TOP"><P></P></TD>
<TD WIDTH="2%" VALIGN="TOP"><P></P></TD>
<TD WIDTH="17%" VALIGN="TOP"><P></P></TD>
</TR>
<TR>
<TD STYLE="border-bottom: black 1.5pt solid" WIDTH="40%" VALIGN="TOP" HEIGHT=16>
<FONT SIZE=2><P ALIGN="CENTER">&nbsp;</P>
<P ALIGN="CENTER">/s/ Dr. Robin L. Smith</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=3>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="40%" VALIGN="TOP" HEIGHT=3>
<FONT SIZE=2><P ALIGN="CENTER">&nbsp;</P>
<P ALIGN="CENTER">Director</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=3>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="17%" VALIGN="TOP" HEIGHT=3>
<FONT SIZE=2><P ALIGN="CENTER">&nbsp;</P>
<P ALIGN="CENTER">August 15, 2019</FONT></TD>
</TR>
<TR><TD WIDTH="40%" VALIGN="TOP" HEIGHT=3>
<FONT SIZE=2><P ALIGN="CENTER">Dr. Robin L. Smith</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=3>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="40%" VALIGN="TOP" HEIGHT=3>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP" HEIGHT=3>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="17%" VALIGN="TOP" HEIGHT=3>
<FONT SIZE=2><P>&nbsp;</FONT></TD>
</TR>
<TR><TD WIDTH="40%" VALIGN="TOP">
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP">
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="40%" VALIGN="TOP">
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="2%" VALIGN="TOP">
<FONT SIZE=2><P>&nbsp;</FONT></TD>
<TD WIDTH="17%" VALIGN="TOP">
<FONT SIZE=2><P>&nbsp;</FONT></TD>
</TR>
</TABLE>



<P> &nbsp; </P>


<HR WIDTH="100%">


<P> &nbsp; </P>


</BODY>
</HTML>
[{"type": "S-8", "sequence": "1", "filename": "s8body.htm", "description": "S-8", "secsgml_size_bytes": 63492}]
{"company-data": {"conformed-name": "SEELOS THERAPEUTICS, INC.", "cik": "0001017491", "assigned-sic": "2834", "irs-number": "870449967", "state-of-incorporation": "NV", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-233305", "film-number": "191030645"}, "business-address": {"street1": "300 PARK AVENUE", "city": "NEW YORK", "state": "NY", "zip": "10017", "phone": "(646) 998-6475"}, "mail-address": {"street1": "300 PARK AVENUE", "city": "NEW YORK", "state": "NY", "zip": "10017"}, "former-company": [{"former-conformed-name": "APRICUS BIOSCIENCES, INC.", "date-changed": "20100914"}, {"former-conformed-name": "NEXMED INC", "date-changed": "19970311"}]}
August 15, 2019 S-8 DOC
As filed with the Securities and Exchange Commission on August 15, 2019
Registration No. 333-
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
__________________________________________________________________________________________________________
FORM S-8
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
__________________________________________________________________________________________________________
Seelos Therapeutics, Inc.
(Exact name of Registrant as specified in its charter)
__________________________________________________________________________________________________________
Nevada
87-0449967
(State or other jurisdiction of
incorporation or organization)
(I.R.S. Employer
Identification No.)
300 Park Avenue, 12th Floor
New York, NY 10022
(Address of principal executive offices, including zip code)
__________________________________________________________________________________________________________
Seelos Therapeutics, Inc. 2019 Inducement Plan
(Full title of the plans)
Raj Mehra, Ph.D.
President, Chief Executive Officer and Chairman of the Board of Directors
Seelos Therapeutics, Inc.
300 Park Avenue, 12th Floor
New York, NY 10022
(646) 998-6475
(Name, address and telephone number, including area code, of agent for service)
__________________________________________________________________________________________________________
Copies to:
Jeffrey T. Hartlin, Esq.
Paul Hastings LLP
1117 S. California Avenue
Palo Alto, California 94304
(650) 320-1800
__________________________________________________________________________________________________________
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the
definitions of "large accelerated filer," "accelerated filer," "smaller reporting company," and "emerging growth company" in Rule 12b-2 of the
Exchange Act.
Large accelerated filer
¨
Accelerated filer
¨
Non-accelerated filer
¨
Smaller reporting company
x
Emerging growth company
¨
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised
financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act.
¨
CALCULATION OF REGISTRATION FEE
Title of Securities to be Registered
Amount
to be
Registered
(1)
Proposed
Maximum
Offering Price
Per Share
Proposed
Maximum
Aggregate
Offering Price
Amount of
Registration Fee
Common Stock, $0.001 par value per share, reserved for issuance pursuant to the Seelos Therapeutics, Inc. 2019 Inducement Plan
902,715
$1.63
(2)
$1,471,425.45
(2)
$178.34
Common Stock, $0.001 par value per share, issuable pursuant to outstanding options granted under the Seelos Therapeutics, Inc. 2019 Inducement Plan
97,285
$1.60
(3)
$155,656.00
(3)
$18.86
TOTAL:
1,000,000
-
$1,627,081.45
$197.20
(1)
Pursuant to Rule 416(a) of the Securities Act of 1933, as amended (the "Securities Act"), this Registration Statement on Form S-8 (the
"Registration Statement") shall also cover any additional shares of common stock, $0.001 par value per share (the "Common Stock"), of the Registrant (defined below)
that become issuable under the Seelos Therapeutics, Inc. 2019 Inducement Plan (the "2019 Plan"), by reason of any stock dividend, stock split, recapitalization or other similar
transaction effected without receipt of consideration that increases the number of the Registrant's outstanding shares of Common Stock.
(2)
Estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rules 457(c) and 457(h) of the Securities Act. The
proposed maximum aggregate offering price per share and the proposed maximum aggregate offering price with respect to these shares are calculated based on the average of the high and
low prices of the Common Stock as reported on the Nasdaq Capital Market on August 14, 2019, a date within five business days prior to the filing of this Registration Statement.
(3)
Estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rule 457(h) of the Securities Act. The proposed maximum
offering price per share and the proposed maximum aggregate offering price are calculated based on $1.60 per share, which is the exercise price per share for the options issued and
outstanding under the 2019 Plan.
EXPLANATORY NOTE
Seelos Therapeutics, Inc. (the "Registrant") has prepared this registration statement (this "Registration Statement") in accordance with the
requirements of Form S-8 under the Securities Act to register 1,000,000 shares of Common Stock reserved for issuance under the 2019 Plan to new employees hired by the Registrant or its
subsidiaries.
PART I
INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS
The document(s) containing the information specified in Part I will be sent or given to employees as specified by Rule 428(b)(1) of the Securities Act. Such
documents are not being filed with the Securities and Exchange Commission (the "Commission") either as part of this Registration Statement or as prospectuses or prospectus
supplements pursuant to Rule 424 of the Securities Act. Such documents and the documents incorporated by reference in this Registration Statement pursuant to Item 3 of Part II hereof, taken
together, constitute a prospectus that meets the requirements of Section 10(a) of the Securities Act.
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 3. Incorporation of Documents by Reference.
The following documents filed by the Registrant with the Commission are hereby incorporated by reference into this Registration Statement:
(a)
The Registrant's Annual Report on Form 10-K for
the fiscal year ended December 31, 2018, filed with the Commission on March 28, 2019
;
(b)
The Registrant's Quarterly Reports on Form 10-Q for the quarters ended (i)
March 31, 2019, filed with the Commission on May 21,
2019
, and (ii)
June 30, 2019,
filed with the Commission on August 1, 2019
;
(c)
The Registrant's Definitive Proxy
Statement on Schedule 14A filed with the Commission on April 12, 2019
;
(d)
The Registrant's Current Reports on Form 8-K filed with the Commission on (i)
January 4, 2019
, (ii)
January 16, 2019
, (iii)
January 24, 2019 at 8:05 a.m. Eastern Time
,
(iv)
January 24, 2019 at 8:06 a.m. Eastern
Time
, (v)
February 6,
2019
and (vi)
February 19,
2019
; (vii)
March 8,
2019
; (viii)
March 26,
2019
; (ix)
April 8,
2019
; (x)
May 13,
2019
; (xi)
June 18,
2019
; (xii)
June 27, 2019
;
and (xiii)
August 14, 2019
;
(e)
The Registrant's Current Reports on Form 8-K/A filed with the Commission on (i)
January 30, 2019
and (ii)
March 1, 2019
; and
(f)
The description of the Registrant's common stock set forth in the Registrant's
Registration Statement on Form 8-A (File No. 000-22245), filed
with the Commission on April 10, 2000
, including any amendments or reports filed for the purpose of updating such description.
All other reports and other documents subsequently filed by the Registrant pursuant to Sections 13(a), 13(c), 14 or 15(d) of the Securities
Exchange Act of 1934, as amended (the "Exchange Act"), prior to the filing of a post-effective amendment which indicates that all securities offered hereby have been sold or which
deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference into this Registration Statement and to be a part of this Registration Statement from the date
of the filing of such reports and documents, except as to any portion of any future annual or quarterly report to shareholders or document or current report furnished under Items 2.02 or 7.01 of
Form 8-K that is not deemed filed under such provisions.
For the purposes of this Registration Statement, any statement contained in a document incorporated or deemed to be incorporated by reference herein shall be
deemed to be modified or superseded to the extent that a statement contained herein or in any other subsequently filed document that also is or is deemed to be incorporated by reference
herein modifies or supersedes such statement. Any such statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this
Registration Statement.
You should rely only on the information provided or incorporated by reference in this Registration Statement or any related prospectus. The Registrant has not
authorized anyone to provide you with different information. You should not assume that the information in this Registration Statement or any related prospectus is accurate as of any date other
than the date on the front of the document.
You may contact the Registrant in writing or orally to request copies of the above-referenced filings, without charge (excluding exhibits to such documents unless such
exhibits are specifically incorporated by reference into the information incorporated by reference into this Registration Statement). Requests for such information should be directed to:
Seelos Therapeutics, Inc.
300 Park Avenue, 12th Floor
New York, NY 10022
(646) 998-6475
Item 4. Description of Securities.
Not applicable.
Item 5. Interests of Named Experts and Counsel.
Not applicable.
Item 6. Indemnification of Directors and Officers.
The Registrant's officers and directors are indemnified under Nevada law, the Registrant's Amended and Restated Articles of Incorporation, as amended, and its
Fourth Amended and Restated Bylaws, as amended, against certain liabilities. The Registrant's Amended and Restated Articles of Incorporation, as amended, require the Registrant to
indemnify its directors and officers to the fullest extent permitted by the laws of the State of Nevada in effect from time to time.
Pursuant to its Amended and Restated Articles of Incorporation, as amended, none of the Registrant's directors or officers shall be personally liable to the Registrant or
its stockholders for damages for breach of fiduciary duty as a director or officer, except for (1) acts or omissions which involve intentional misconduct, fraud or a knowing violation of law, or (2)
the payment of dividends in violation of the applicable statutes of Nevada. Further, the Registrant's Amended and Restated Articles of Incorporation, as amended, provide that if Nevada law is
amended to authorize corporate action further eliminating or limiting the personal liability of directors or officers, the liability of a director or officer of the corporation shall be eliminated or limited
to the fullest extent permitted by Nevada law, as so amended from time to time. However, Nevada Revised Statutes 78.138 currently provides that, except as otherwise provided in the Nevada
Revised Statutes, a director or officer shall not be individually liable to the Registrant or its stockholders or creditors for any damages as a result of any act or failure to act in his or her capacity
as a director or officer unless it is proven that (i) the presumption established by Nevada Revised Statutes 78.138(3) has been rebutted, (ii) the director's or officer's acts or omissions
constituted a breach of his or her fiduciary duties as a director or officer, and (iii) such breach involved intentional misconduct, fraud or a knowing violation of the law.
Pursuant to the Registrant's Amended and Restated Articles of Incorporation, as amended, it shall indemnify any person who was or is a party or is threatened to be
made a party to any threatened, pending or completed action, suit or proceeding, by reason of the fact that he or she is or was or has agreed to become a director or officer of the Registrant or
is serving at the Registrant's request as a director or officer of another entity or enterprise or by reason
of actions alleged to have been taken or omitted in such capacity or in any other capacity
while serving as a director or officer, to the fullest extent permitted by applicable law, against any and all loss, liability and expenses, including attorneys' fees, costs, damages, judgments, fines,
amounts paid in settlement, and ERISA excise taxes or penalties, actually and reasonably incurred by such person in connection with such action, suit or proceeding, including any appeal. This
right to indemnification shall continue for any person who has ceased to be a director or officer and shall inure to the benefit of his or her heirs, next of kin, executors, administrators and legal
representatives.
The Registrant's Amended and Restated Articles of Incorporation, as amended, also provide that it shall pay the expenses of directors and officers incurred as a party to
any threatened, pending or completed action, suit or proceeding, as they are incurred and in advance of the final disposition of the action, suit or proceeding, but, if applicable law so requires,
only upon receipt by the Registrant of an undertaking from the director or officer to repay the advanced amounts in the event it is ultimately determined by a final decision, order or decree of a
court of competent jurisdiction that the director or officer is not entitled to be indemnified for such expenses.
The Registrant's Fourth Amended and Restated Bylaws, as amended, provide that the Registrant shall indemnify and hold harmless, to the fullest extent permitted by
the laws of the State of Nevada, each director or officer of the corporation who was or is a party to, or is threatened to be made a party to, or is otherwise involved in, any threatened, pending,
or completed action, suit or proceeding (whether civil, criminal, administrative or investigative, and including, without limitation, an action, suit or proceeding by or in the right of the corporation),
by reason of the fact that he or she is or was a director or officer of the corporation or is or was serving in any capacity at the request of the corporation as a director, officer, employee, agent,
partner, member, manager or fiduciary of, or in any other capacity for, another corporation or any partnership, joint venture, limited liability company, trust or other enterprise. Such
indemnification shall be against all expense, liability and loss (including, without limitation, attorneys' fees, judgments, fines, taxes, penalties and amounts paid or to be paid in settlement)
reasonably incurred or suffered by such director or officer in connection with any such action, suit or proceeding; provided that such director or officer either is not liable pursuant to Nevada
Revised Statutes 78.138 or acted in good faith and in a manner he or she reasonably believed to be in or not opposed to the best interests of the corporation, and with respect to any such
action, suit or proceeding that is criminal in nature, had no reasonable cause to believe that his or her conduct was unlawful. No such indemnification shall be made to or on behalf of any such
director or officer if a final adjudication establishes that his or her acts or omissions involved intentional misconduct, fraud or a knowing violation of law and was material to the cause of action,
or for any expenses of such director or officer incurred in his or her capacity as a stockholder. The Fourth Amended and Restated Bylaws, as amended, also require that the expenses of such
directors and officers must be paid by the corporation (or through insurance maintained, or other financial arrangements made, by the corporation) as such expenses are incurred and in
advance of the final disposition of such action, suit or proceeding, upon receipt of an undertaking by or on behalf of such director or officer to repay the amount if it is ultimately determined by a
court of competent jurisdiction that he or she is not entitled to be indemnified by the corporation. Any indemnification of directors and officers under the Fourth Amended and Restated Bylaws,
as amended, shall inure to the benefit of their respective heirs, executors and administrators.
Section 78.7502 of the Nevada Revised Statutes permits a corporation to indemnify a present or former director, officer, employee or agent of the corporation, or of
another entity or enterprise for which such person is or was serving in such capacity at the request of the corporation, who was or is a party or is threatened to be made a party to any
threatened, pending or completed action, suit or proceeding, except an action by or in the right of the corporation, against expenses, including attorneys' fees, judgments, fines and amounts
paid in settlement actually and reasonably incurred in connection therewith, arising by reason of such person's service in such capacity if such person (i) is not liable pursuant to Section 78.138
of the Nevada Revised Statutes, or (ii) acted in good faith and in a manner which he or she reasonably believed to be in or not opposed to the best interests of the corporation and, with respect
to a criminal action or proceeding, had no reasonable cause to believe his or her conduct was unlawful. In the case of actions brought by or in the right of the corporation, however, no
indemnification may be made for any claim, issue or matter as to which such person has been adjudged by a court of competent jurisdiction, after exhaustion of all appeals therefrom, to be
liable to the corporation or for amounts paid in settlement to the corporation, unless and only to the extent that the court in which the action or suit was brought or other court of competent
jurisdiction determines upon application that in view of all the circumstances of the case, such person is fairly and reasonably entitled to indemnity for such expenses as the court deems proper.
Section 78.751 of the Nevada Revised Statutes permits any discretionary indemnification under Section 78.7502 of the Nevada Revised Statutes, unless ordered by a
court or advanced to a director or officer by the corporation in accordance with the Nevada Revised Statutes, to be made by a corporation only as authorized in each specific case upon a
determination that indemnification of the director, officer, employee or agent is proper in the circumstances. Such determination must be made (1) by the stockholders, (2) by the board of
directors by majority vote of a quorum consisting of directors who were not parties to the action, suit or proceeding, (3) if a majority vote of a quorum consisting of directors who were not parties
to the action, suit or proceeding so orders, by independent legal counsel in a written opinion, or (4) if a quorum consisting of directors who were not parties to the action, suit or proceeding
cannot be obtained, by independent legal counsel in a written opinion.
The Registrant maintains a general liability insurance policy that covers certain liabilities of directors and officers of the corporation arising out of claims based on acts or
omissions in their capacities as directors or officers.
See also the undertakings set out in response to Item 9 herein.
Item 7. Exemption from Registration Claimed.
Not applicable.
Item 8. Exhibits.
Exhibit
Number
Description of Document
3.1
Amended and Restated Articles of Incorporation of the Registrant (incorporated herein by reference to Exhibit 2.1 to the Registrant's Registration Statement on Form 10-SB filed
with the Securities and Exchange Commission on March 14, 1997).
3.2
Certificate of Amendment to Articles of Incorporation of the Registrant, dated June 22, 2000 (incorporated herein by reference to Exhibit 3.2 to the Registrant's Form 10-K
filed with the Securities and Exchange Commission on March 31, 2003).
3.3
Certificate of Amendment to Articles of Incorporation of the Registrant, dated June 14, 2005 (incorporated herein by reference to Exhibit 3.4 to the Registrant's Form 10-K
filed with the Securities and Exchange Commission on March 16, 2006).
3.4
Certificate of Amendment to Amended and Restated Articles of Incorporation of the Registrant, dated March 3, 2010 (incorporated herein by reference to Exhibit 3.6 to the
Registrant's Annual Report on Form 10-K filed with the Securities and Exchange Commission on March 31, 2010).
3.5
Certificate of Correction to Certificate of Amendment to Amended and Restated Articles of Incorporation of the Registrant, dated March 3, 2010 (incorporated herein by
reference to Exhibit 3.7 to the Registrant's Annual Report on Form 10-K filed with the Securities and Exchange Commission on March 31, 2010).
3.6
Certificate of Designation for Series D Junior-Participating Cumulative Preferred Stock (incorporated herein by reference to Exhibit 3.1 to the Registrant's Current Report
on Form 8-A12G filed with the Securities and Exchange Commission on March 24, 2011).
3.7
Certificate of Change filed with the Nevada Secretary of State (incorporated herein by reference to Exhibit 3.1 to the Registrant's Current Report on Form 8-K filed with the
Securities and Exchange Commission on June 17, 2010).
Exhibit
Number
Description of Document
3.8
Certificate of Amendment to Amended and Restated Articles of Incorporation of the Registrant, dated September 10, 2010 (incorporated herein by reference to Exhibit 3.1
to the Registrant's Current Report on Form 8-K filed with the Securities and Exchange Commission on September 10, 2010).
3.9
Certificate of Withdrawal of Series D Junior Participating Cumulative Preferred Stock, dated May 15, 2013 (incorporated herein by reference to Exhibit 3.1 to the
Registrant's Current Report on Form 8-K filed with the Securities and Exchange Commission on May 16, 2013).
3.10
Certificate of Change filed with the Nevada Secretary of State (incorporated herein by reference to Exhibit 3.1 to the Registrant's Form 8-K filed with the Securities and
Exchange Commission on October 25, 2016).
3.11
Certificate of Amendment filed with the Nevada Secretary of State (incorporated herein by reference to Exhibit 3.10 to the Registrant's Quarterly Report on Form 10-Q filed
with the Securities and Exchange Commission on August 2, 2017).
3.12
Certificate of Amendment filed with the Nevada Secretary of State (incorporated herein by reference to Exhibit 3.12 to the Registrant's Quarterly Report on Form 10-Q filed
with the Securities and Exchange Commission on August 9, 2018).
3.13
Certificate of Amendment related to the Share Increase Amendment, filed January 23, 2019 (incorporated herein by reference to Exhibit 3.1 to the Registrant's Current
Report on Form 8-K filed with the Securities and Exchange Commission on January 24, 2019 at 8:05 Eastern Time).
3.14
Certificate of Amendment related to the Name Change, filed January 23, 2019 (incorporated herein by reference to Exhibit 3.2 to the Registrant's Current Report on Form
8-K filed with the Securities and Exchange Commission on January 24, 2019 at 8:05 Eastern Time).
3.15
Amended and Restated Bylaws, dated January 24, 2019 (incorporated herein by reference to Exhibit 3.3 to the Registrant's Current Report on Form 8-K filed with the
Securities and Exchange Commission on January 24, 2019 at 8:05 Eastern Time).
4.1
Form of Common Stock Certificate (incorporated herein by reference to Exhibit 4.1 to the Registrant's Current Report on Form 8-K filed with the Securities and Exchange
Commission on March 24, 2011).
4.2
Seelos Therapeutics, Inc. 2019 Inducement Plan (incorporated herein by reference to Exhibit 10.1 to the Registrant's Current Report on Form 8-K filed with the Securities
and Exchange Commission on August 14, 2019).
4.3
Form of Stock Option Agreement under the Seelos Therapeutics, Inc. 2019 Inducement Plan.
5.1
Opinion of Brownstein Hyatt Farber Schreck, LLP.
23.1
Consent of BDO USA LLP, Independent Registered Public Accounting Firm.
23.2
Consent of KPMG LLP, Independent Registered Public Accounting Firm.
23.3
Consent of Brownstein Hyatt Farber Schreck, LLP (included in Exhibit 5.1).
24.1
Power of Attorney (included on signature page).
Item 9. Undertakings.
A. The undersigned Registrant hereby undertakes:
(1) To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:
(i) To include any prospectus required by Section 10(a)(3) of the Securities Act;
(ii) To reflect in the prospectus any facts or events arising after the effective date of the registration statement (or the most recent post-effective amendment thereof)
which, individually or in the aggregate, represent a fundamental change in the information set forth in the registration statement. Notwithstanding the foregoing, any increase or decrease in
volume of securities offered (if the total dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum
offering range may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the changes in volume and price represent no more than a 20
percent change in the maximum aggregate offering price set forth in the "Calculation of Registration Fee" table in the effective registration statement; and
(iii) To include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement or any material change to such
information in the Registration Statement.
Provided, however
, that paragraphs (A)(1)(i) and (A)(1)(ii) do not apply if the information required to be included in a post-effective amendment by those
paragraphs is contained in periodic reports filed with or furnished to the Commission by the Registrant pursuant to Section 13 or Section 15(d) of the Exchange Act that are incorporated by
reference in this Registration Statement.
(2) That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement
relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.
(3) To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the
offering.
B. The undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the Registrant's annual report
pursuant to Section 13(a) or Section 15(d) of the Exchange Act (and, where applicable, each filing of an employee benefit plan's annual report pursuant to Section 15(d) of the Exchange Act)
that is incorporated by reference in the Registration Statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at
that time shall be deemed to be the initial bona fide offering thereof.
C. Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the Registrant pursuant to the
foregoing provisions, or otherwise, the Registrant has been advised that in the opinion of the Commission such indemnification is against public policy as expressed in the Securities Act and is,
therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer or
controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being
registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such
indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of New York,
State of New York, on August 15, 2019.
SEELOS THERAPEUTICS, INC.
By:
/s/ Raj Mehra, Ph.D.
Raj Mehra, Ph.D.
President and Chief Executive Officer
POWER OF ATTORNEY
KNOW ALL PERSONS BY THESE PRESENTS
, that each person whose signature appears below constitutes and appoints Raj Mehra, Ph.D. his or her true and
lawful attorney-in-fact and agent, with full power of substitution and resubstitution, for him or her and in his or her name, place and stead, in any and all capacities, to sign any and all
amendments (including post-effective amendments) to this Registration Statement, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the
Securities and Exchange Commission, granting unto said attorney-in-fact and agent full power and authority to do and perform each and every act and thing requisite and necessary to be done
in connection therewith, as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorney-in-fact and agent or his substitutes or
substitute, may lawfully do or cause to be done by virtue hereof.
Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed by the following persons in the capacities and on the dates indicated.
Signature
Title
Date
/s/ Raj Mehra, Ph.D.
President, Chief Executive Officer, Chairman of the Board and Interim Chief Financial Officer
August 15, 2019
Raj Mehra, Ph.D.
(Principal Executive Officer, Principal Financial and Accounting Officer)
/s/ Brian Lian, Ph.D.
Director
August 15, 2019
Brian Lian, Ph.D.
/s/ Daniel J. O'Connor, J.D.
Director
August 15, 2019
Daniel J. O'Connor, J.D.
/s/ Richard W. Pascoe
Director
August 15, 2019
Richard W. Pascoe
/s/ Dr. Robin L. Smith
Director
August 15, 2019
Dr. Robin L. Smith