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    <div style="text-align: center; font-weight: bold;">As filed with the Securities and Exchange Commission on February 29, 2024</div>
    <br>
    <div style="text-align: right; font-weight: bold;">Registration No. 333-</div>
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      <div style="text-align: center; font-size: 14pt; font-weight: bold;">UNITED STATES</div>
      <div style="text-align: center; font-size: 14pt; font-weight: bold;">SECURITIES AND EXCHANGE COMMISSION</div>
      <div style="text-align: center; font-size: 12pt; font-weight: bold;">WASHINGTON, D.C. 20549</div>
      <br>
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      <div style="text-align: center; font-weight: bold;"> <br>
      </div>
      <div style="text-align: center; font-size: 18pt; font-weight: bold;">FORM S-8</div>
      <div style="text-align: center; font-weight: bold;">REGISTRATION STATEMENT</div>
      <div style="text-align: center; font-style: italic; font-weight: bold;">UNDER</div>
      <div style="text-align: center; font-style: italic; font-weight: bold;">THE SECURITIES ACT OF 1933</div>
      <br>
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      <div style="text-align: center; font-weight: bold;"> <br>
      </div>
      <div style="text-align: center; font-size: 24pt; font-weight: bold;">Quantum-Si Incorporated</div>
      <div style="text-align: center; font-weight: bold;">(Exact name of registrant as specified in its charter)</div>
      <div style="text-align: center; font-weight: bold;"> <br>
      </div>
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            <td style="width: 49%; vertical-align: top;">
              <div style="text-align: center; font-weight: bold;"> Delaware</div>
            </td>
            <td style="width: 2%; vertical-align: top;"><br>
            </td>
            <td style="width: 49%; vertical-align: top;">
              <div style="text-align: center; font-weight: bold;">85-1388175</div>
            </td>
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            <td nowrap="nowrap" style="width: 49%; vertical-align: top;">
              <div style="text-align: center; font-weight: bold;">(State or other jurisdiction of incorporation or organization)</div>
            </td>
            <td style="width: 2%; vertical-align: top;"><br>
            </td>
            <td nowrap="nowrap" style="width: 49%; vertical-align: top;">
              <div style="text-align: center; font-weight: bold;">(I.R.S. Employer Identification No.)</div>
            </td>
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      </table>
      <div><br>
      </div>
      <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

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              <div style="text-align: center; font-weight: bold;">29 Business Park Drive</div>
              <div style="text-align: center; font-weight: bold;">Branford, Connecticut</div>
            </td>
            <td style="width: 2%; vertical-align: top;"><br>
            </td>
            <td style="width: 49%; vertical-align: bottom; text-align: center;">
              <div style="font-weight: bold;">06405</div>
            </td>
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            <td rowspan="1" style="width: 49%; vertical-align: top;">
              <div style="text-align: center; font-weight: bold;">(Address of Principal Executive Offices)</div>
            </td>
            <td rowspan="1" style="width: 2%; vertical-align: top;">&#160;</td>
            <td rowspan="1" style="width: 49%; vertical-align: top;">
              <div style="text-align: center; font-weight: bold;">(Zip Code)</div>
            </td>
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      </table>
      <div style="text-align: center; font-weight: bold;">2021 Equity Incentive Plan</div>
      <div style="text-align: center; font-weight: bold;">(Full title of the plan)</div>
      <div><br>
      </div>
      <div style="text-align: center; font-weight: bold;">Jeffrey Hawkins</div>
      <div style="text-align: center; font-weight: bold;">Chief Executive Officer</div>
      <div style="text-align: center; font-weight: bold;">Quantum-Si Incorporated</div>
      <div style="text-align: center; font-weight: bold;"><a name="z_Hlk155701817"></a>29 Business Park Drive</div>
      <div style="text-align: center; font-weight: bold;">Branford, Connecticut 06405</div>
      <div style="text-align: center; font-weight: bold;">(Name and address of agent for service)</div>
      <div><br>
      </div>
      <div style="text-align: center; font-weight: bold;">(866) 688&#8209;7374</div>
      <div style="text-align: center; font-weight: bold;">&#160;(Telephone number, including area code, of agent for service)</div>
      <br>
      <hr noshade="noshade" align="center" style="background-color: #000000; border-bottom: medium none; border-left: medium none; border-right: medium none; border-top: medium none; margin: 0px auto; height: 2px; width: 100%; color: #000000; text-align: center;">
      <div style="text-align: justify; text-indent: 18pt; color: #000000;"> <br>
      </div>
      <div style="text-align: justify; text-indent: 18pt; color: #000000;">Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company.
        See the definitions of &#8220;large accelerated filer,&#8221; &#8220;accelerated filer,&#8221; &#8220;smaller reporting company,&#8221; and &#8220;emerging growth company&#8221; in Rule 12b-2 of the Exchange Act.</div>
      <br>
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            <td style="width: 51.5%; vertical-align: top;">
              <div style="color: rgb(0, 0, 0);">Large accelerated filer &#9744;</div>
            </td>
            <td style="width: 48.38%; vertical-align: top;">
              <div style="color: rgb(0, 0, 0);">Accelerated filer &#9744;<a name="Check1"></a></div>
            </td>
          </tr>
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            <td style="width: 51.5%; vertical-align: top;">
              <div style="color: rgb(0, 0, 0);">Non-accelerated filer&#160;&#160; &#9746;</div>
            </td>
            <td style="width: 48.38%; vertical-align: top;">
              <div style="color: rgb(0, 0, 0);">Smaller reporting company &#9746;</div>
            </td>
          </tr>
          <tr>
            <td style="width: 51.5%; vertical-align: top;"><br>
            </td>
            <td style="width: 48.38%; vertical-align: top;">
              <div style="color: rgb(0, 0, 0);">Emerging growth company &#9744;</div>
            </td>
          </tr>

      </table>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 18pt; color: #000000;">If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial
        accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. &#9744;</div>
      <div>&#160;</div>
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      <div style="text-align: center; font-weight: bold;">EXPLANATORY NOTE</div>
      <div>&#160;</div>
      <div style="text-align: justify;">This registration statement registers an aggregate of 5,670,796 additional shares of Class A common stock, par value $0.0001 per share, of Quantum-Si Incorporated (the &#8220;Registrant&#8221;) reserved under the Quantum-Si
        Incorporated 2021 Equity Incentive Plan (the &#8220;2021 Plan&#8221;), representing an increase of 5,670,796 shares reserved under the 2021 Plan effective January 1, 2024 by operation of the 2021 Plan&#8217;s &#8220;evergreen&#8221; provision. This registration statement
        registers additional securities of the same class as other securities for which a registration statement filed on Form S-8 (File No. 333-259271) relating to an employee benefit plan is effective. The information contained in the Registrant&#8217;s
        registration statement on Form S-8 filed with the Securities and Exchange Commission on September 2, 2021 (File No. 333-259271) is hereby incorporated by reference pursuant to General Instruction E of Form S-8.</div>
      <div>&#160;</div>
      <div style="text-align: center; font-weight: bold;">PART II</div>
      <div>&#160;</div>
      <div style="text-align: center; font-weight: bold;">INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</div>
      <div>&#160;</div>
      <div>
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              <td style="width: 36pt; vertical-align: top; color: rgb(0, 0, 0); font-weight: bold;">Item 6.</td>
              <td style="width: auto; vertical-align: top;">
                <div style="color: rgb(0, 0, 0); font-weight: bold;">Indemnification of Directors and Officers.</div>
              </td>
            </tr>

        </table>
      </div>
      <div>
        <div><br>
        </div>
        <div style="text-indent: 24.5pt; color: #000000;">Section 145 of the Delaware General Corporation Law (the &#8220;DGCL&#8221;), permits a corporation to indemnify its directors and officers against expenses, including attorneys&#8217; fees, judgments, fines and
          amounts paid in settlements actually and reasonably incurred by them in connection with any action, suit or proceeding brought by third parties. The directors or officers must have acted in good faith and in a manner they reasonably believed to
          be in or not opposed to the best interests of the corporation and, with respect to any criminal action or proceeding, had no reason to believe their conduct was unlawful. In a derivative action, an action only by or in the right of the
          corporation, indemnification may be made only for expenses, including attorney&#8217;s fees, actually and reasonably incurred by directors and officers in connection with the defense or settlement of an action or suit, and only with respect to a matter
          as to which they acted in good faith and in a manner they reasonably believed to be in or not opposed to the best interests of the corporation. No indemnification shall be made if such person shall have been adjudged to be liable to the
          corporation, unless and only to the extent that the court in which the action or suit was brought determines upon application that the defendant officers or directors are fairly and reasonably entitled to indemnity for such expenses despite such
          adjudication of liability. The amended and restated certificate of incorporation, as amended, of the registrant provides that the registrant may indemnify its directors, officers, employees or agents to the fullest extent permitted by applicable
          law and the amended and restated bylaws of the registrant provide that the registrant shall indemnify its directors and officers to the fullest extent permitted by applicable law.</div>
      </div>
      <div>
        <div><br>
        </div>
        <div style="text-indent: 24.5pt; color: #000000;">Section 102(b)(7) of the DGCL permits a corporation to provide in its certificate of incorporation that a director or officer of the corporation shall not be personally liable to the corporation or
          its stockholders for monetary damages for breach of fiduciary duty as a director or officer, except for liability of (1) a director or officer for any breach of the director&#8217;s or officer&#8217;s duty of loyalty to the corporation or its stockholders,
          (2) a director or officer for acts or omissions not in good faith or which involve intentional misconduct or a knowing violation of law, (3) a director for payments of unlawful dividends or unlawful stock purchases or redemptions, (4) a director
          or officer for any transaction from which the director or officer derived an improper personal benefit, or (5) an officer in any action by or in the right of the corporation. The amended and restated certificate of incorporation, as amended, of
          the registrant provides for such limitation of liability with respect to directors and officers of the corporation.</div>
        <div>&#160;</div>
        <div style="text-indent: 24.5pt; color: #000000;">We have entered into indemnification agreements with each of our directors and officers in which we have agreed to indemnify and hold harmless, and also advance expenses as incurred, to the fullest
          extent permitted under applicable law, against all expenses, losses and liabilities incurred by the indemnitee or on the indemnitee&#8217;s behalf arising from the fact that such person is or was a director, officer, employee or agent of our company or
          our subsidiaries.</div>
        <div>&#160;</div>
        <div style="text-indent: 24.5pt; color: #000000;">The indemnification rights set forth above shall not be exclusive of any other right which an indemnified person may have or hereafter acquire under any statute, our amended and restated certificate
          of incorporation, as amended, our amended and restated bylaws, any agreement, any vote of stockholders or disinterested directors or otherwise.</div>
        <div>&#160;</div>
        <div style="text-indent: 24.5pt; color: #000000;">We maintain standard policies of insurance that provide coverage (1) to our directors and officers against loss rising from claims made by reason of breach of duty or other wrongful act and (2) to
          us with respect to indemnification payments that we may make to such directors and officers.</div>
      </div>
      <div> <br>
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            <td style="width: 36pt; vertical-align: top; font-weight: bold;">Item 8.</td>
            <td style="width: auto; vertical-align: top;">
              <div style="font-weight: bold;">Exhibits.</div>
            </td>
          </tr>

      </table>
      <div> <br>
      </div>
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            <td nowrap="nowrap" style="width: 6%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="font-weight: bold;">Exhibit</div>
              <div style="font-weight: bold;">Number</div>
            </td>
            <td nowrap="nowrap" style="width: 49%; vertical-align: bottom; padding-bottom: 2px;">
              <div style="text-align: center; font-weight: bold;"><u>Exhibit Description</u></div>
            </td>
            <td nowrap="nowrap" style="width: 8%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="font-weight: bold;">Filed</div>
              <div style="font-weight: bold;">Herewith</div>
            </td>
            <td nowrap="nowrap" style="width: 13%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center; font-weight: bold;">Incorporated</div>
              <div style="text-align: center; font-weight: bold;">by Reference</div>
              <div style="text-align: center; font-weight: bold;">herein from</div>
              <div style="text-align: center; font-weight: bold;">Form or</div>
              <div style="text-align: center; font-weight: bold;">Schedule</div>
            </td>
            <td nowrap="nowrap" style="width: 11%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center; font-weight: bold;">Filing Date</div>
            </td>
            <td nowrap="nowrap" style="width: 13%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center; font-weight: bold;">SEC File/</div>
              <div style="text-align: center; font-weight: bold;">Reg. Number</div>
            </td>
          </tr>
          <tr>
            <td nowrap="nowrap" style="width: 6%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div><a href="https://www.sec.gov/Archives/edgar/data/1816431/000114036123038382/brhc20056874_ex3-1.htm">4.1</a></div>
            </td>
            <td style="width: 49%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div>Second Amended and Restated Certificate of Incorporation of the Registrant, as amended.</div>
            </td>
            <td style="width: 8%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
            <td style="width: 13%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">10-Q</div>
              <div style="text-align: center;">(Exhibit 3.1)</div>
            </td>
            <td style="width: 11%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">8/7/2023</div>
            </td>
            <td style="width: 13%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">001-39486</div>
            </td>
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            </td>
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            </td>
            <td style="width: 8%; vertical-align: top;"><br>
            </td>
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            </td>
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            </td>
            <td style="width: 13%; vertical-align: top;"><br>
            </td>
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            <td nowrap="nowrap" style="width: 6%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div><a href="https://www.sec.gov/Archives/edgar/data/1816431/000114036122007334/brhc10034564_ex3-2.htm">4.2</a></div>
            </td>
            <td style="width: 49%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div>Amended and Restated Bylaws of the Registrant.</div>
            </td>
            <td style="width: 8%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
            <td style="width: 13%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">10-K</div>
              <div style="text-align: center;">(Exhibit 3.2)</div>
            </td>
            <td style="width: 11%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">3/1/2022</div>
            </td>
            <td style="width: 13%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">001-39486</div>
            </td>
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            </td>
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            </td>
            <td rowspan="1" style="width: 13%; vertical-align: top;"><br>
            </td>
            <td rowspan="1" style="width: 11%; vertical-align: top;"><br>
            </td>
            <td rowspan="1" style="width: 13%; vertical-align: top;">&#160;</td>
          </tr>
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            <td nowrap="nowrap" style="width: 6%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div><a href="https://www.sec.gov/Archives/edgar/data/1816431/000110465921064151/tm217673d12_ex4-1.htm">4.3</a></div>
            </td>
            <td style="width: 49%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div>Specimen Class A Common Stock Certificate.</div>
            </td>
            <td style="width: 8%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
            <td style="width: 13%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">S-4/A</div>
              <div style="text-align: center;">(Exhibit 4.1)</div>
            </td>
            <td style="width: 11%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">5/11/2021</div>
            </td>
            <td style="width: 13%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">333-253691</div>
            </td>
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            <td nowrap="nowrap" rowspan="1" style="width: 6%; vertical-align: top;"><br>
            </td>
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            </td>
            <td rowspan="1" style="width: 13%; vertical-align: top;"><br>
            </td>
            <td rowspan="1" style="width: 11%; vertical-align: top;"><br>
            </td>
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            </td>
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            <td nowrap="nowrap" style="width: 6%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div><a href="https://www.sec.gov/Archives/edgar/data/1816431/000110465920103448/tm2030387d1_ex4-1.htm">4.4</a></div>
            </td>
            <td style="width: 49%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div>Warrant Agreement, dated as of September 3, 2020, by and between Quantum-Si Incorporated (formerly HighCape Capital Acquisition Corp.) and Continental Stock Transfer &amp; Trust Company.</div>
            </td>
            <td style="width: 8%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
            <td style="width: 13%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">8-K</div>
              <div style="text-align: center;">(Exhibit 4.1)</div>
            </td>
            <td style="width: 11%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">9/9/2020</div>
            </td>
            <td style="width: 13%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">001-39486</div>
            </td>
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            <td style="width: 6%; vertical-align: middle;">&#160;</td>
            <td style="width: 49%; vertical-align: middle;"><br>
            </td>
            <td style="width: 8%; vertical-align: middle;"><br>
            </td>
            <td style="width: 13%; vertical-align: middle;"><br>
            </td>
            <td style="width: 11%; vertical-align: middle;"><br>
            </td>
            <td style="width: 13%; vertical-align: middle;"><br>
            </td>
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            <td nowrap="nowrap" style="width: 6%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div><a href="ef20022562_ex5-1.htm">5.1</a></div>
            </td>
            <td style="width: 49%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div>Opinion of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.</div>
            </td>
            <td style="width: 8%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">X</div>
            </td>
            <td style="width: 13%; vertical-align: bottom; background-color: rgb(204, 238, 255);"><br>
            </td>
            <td style="width: 11%; vertical-align: middle; background-color: rgb(204, 238, 255);"><br>
            </td>
            <td style="width: 13%; vertical-align: middle; background-color: rgb(204, 238, 255);"><br>
            </td>
          </tr>
          <tr>
            <td style="width: 6%; vertical-align: middle;">&#160;</td>
            <td style="width: 49%; vertical-align: middle;">&#160;</td>
            <td style="width: 8%; vertical-align: top;">&#160;</td>
            <td style="width: 13%; vertical-align: middle;"><br>
            </td>
            <td style="width: 11%; vertical-align: middle;"><br>
            </td>
            <td style="width: 13%; vertical-align: middle;"><br>
            </td>
          </tr>
          <tr>
            <td nowrap="nowrap" style="width: 6%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div><a href="ef20022562_ex5-1.htm">23.1</a></div>
            </td>
            <td style="width: 49%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div>Consent of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C. (included in opinion of counsel filed as Exhibit 5.1).</div>
            </td>
            <td style="width: 8%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">X</div>
            </td>
            <td style="width: 13%; vertical-align: bottom; background-color: rgb(204, 238, 255);"><br>
            </td>
            <td style="width: 11%; vertical-align: middle; background-color: rgb(204, 238, 255);"><br>
            </td>
            <td style="width: 13%; vertical-align: middle; background-color: rgb(204, 238, 255);"><br>
            </td>
          </tr>
          <tr>
            <td style="width: 6%; vertical-align: middle;"><br>
            </td>
            <td style="width: 49%; vertical-align: middle;"><br>
            </td>
            <td style="width: 8%; vertical-align: top;"><br>
            </td>
            <td style="width: 13%; vertical-align: middle;"><br>
            </td>
            <td style="width: 11%; vertical-align: middle;"><br>
            </td>
            <td style="width: 13%; vertical-align: middle;"><br>
            </td>
          </tr>
          <tr>
            <td nowrap="nowrap" style="width: 6%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div><a href="ef20022562_ex23-2.htm">23.2</a></div>
            </td>
            <td style="width: 49%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div>Consent of Deloitte &amp; Touche LLP, independent registered public accounting firm.</div>
            </td>
            <td style="width: 8%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">X</div>
            </td>
            <td style="width: 13%; vertical-align: bottom; background-color: rgb(204, 238, 255);"><br>
            </td>
            <td style="width: 11%; vertical-align: middle; background-color: rgb(204, 238, 255);"><br>
            </td>
            <td style="width: 13%; vertical-align: middle; background-color: rgb(204, 238, 255);"><br>
            </td>
          </tr>
          <tr>
            <td style="width: 6%; vertical-align: middle;">&#160;</td>
            <td style="width: 49%; vertical-align: middle;"><br>
            </td>
            <td style="width: 8%; vertical-align: top;"><br>
            </td>
            <td style="width: 13%; vertical-align: middle;"><br>
            </td>
            <td style="width: 11%; vertical-align: middle;"><br>
            </td>
            <td style="width: 13%; vertical-align: middle;"><br>
            </td>
          </tr>
          <tr>
            <td nowrap="nowrap" style="width: 6%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div><a href="#POWEROFATTORNEY">24.1</a></div>
            </td>
            <td style="width: 49%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div>Power of Attorney (included on the signature page hereof).</div>
            </td>
            <td style="width: 8%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">X</div>
            </td>
            <td style="width: 13%; vertical-align: bottom; background-color: rgb(204, 238, 255);"><br>
            </td>
            <td style="width: 11%; vertical-align: middle; background-color: rgb(204, 238, 255);"><br>
            </td>
            <td style="width: 13%; vertical-align: middle; background-color: rgb(204, 238, 255);"><br>
            </td>
          </tr>
          <tr>
            <td nowrap="nowrap" style="width: 6%; vertical-align: top;" rowspan="1"><br>
            </td>
            <td style="width: 49%; vertical-align: top;" rowspan="1"><br>
            </td>
            <td style="width: 8%; vertical-align: top;" rowspan="1"><br>
            </td>
            <td style="width: 13%; vertical-align: bottom;" rowspan="1"><br>
            </td>
            <td style="width: 11%; vertical-align: middle;" rowspan="1"><br>
            </td>
            <td style="width: 13%; vertical-align: middle;" rowspan="1"><br>
            </td>
          </tr>
          <tr>
            <td nowrap="nowrap" style="width: 6%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div><a href="https://www.sec.gov/Archives/edgar/data/1816431/000110465921081560/tm2118908d1_ex10-13d1.htm">99.1+</a></div>
            </td>
            <td style="width: 49%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div>Quantum-Si Incorporated 2021 Equity Incentive Plan.</div>
            </td>
            <td style="width: 8%; vertical-align: bottom; background-color: rgb(204, 238, 255);">&#160;</td>
            <td style="width: 13%; vertical-align: bottom; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">8-K</div>
              <div style="text-align: center;">(Exhibit 10.13.1)</div>
            </td>
            <td style="width: 11%; vertical-align: middle; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">6/15/2021</div>
            </td>
            <td style="width: 13%; vertical-align: middle; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">001-39486</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6%; vertical-align: middle;"><br>
            </td>
            <td style="width: 49%; vertical-align: middle;"><br>
            </td>
            <td style="width: 8%; vertical-align: middle;"><br>
            </td>
            <td style="width: 13%; vertical-align: middle;"><br>
            </td>
            <td style="width: 11%; vertical-align: middle;"><br>
            </td>
            <td style="width: 13%; vertical-align: middle;"><br>
            </td>
          </tr>
          <tr>
            <td nowrap="nowrap" style="width: 6%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div><a href="https://www.sec.gov/Archives/edgar/data/1816431/000110465921081560/tm2118908d1_ex10-13d2.htm">99.2+</a></div>
            </td>
            <td style="width: 49%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div>Form of Stock Option Agreement under 2021 Equity Incentive Plan.</div>
            </td>
            <td style="width: 8%; vertical-align: bottom; background-color: rgb(204, 238, 255);">&#160;</td>
            <td style="width: 13%; vertical-align: bottom; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">8-K</div>
              <div style="text-align: center;">(Exhibit 10.13.2)</div>
            </td>
            <td style="width: 11%; vertical-align: middle; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">6/15/2021</div>
            </td>
            <td style="width: 13%; vertical-align: middle; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">001-39486</div>
            </td>
          </tr>
          <tr>
            <td nowrap="nowrap" rowspan="1" style="width: 6%; vertical-align: top;"><br>
            </td>
            <td rowspan="1" style="width: 49%; vertical-align: top;"><br>
            </td>
            <td rowspan="1" style="width: 8%; vertical-align: bottom;">&#160;</td>
            <td rowspan="1" style="width: 13%; vertical-align: bottom;">&#160;</td>
            <td rowspan="1" style="width: 11%; vertical-align: middle;">&#160;</td>
            <td rowspan="1" style="width: 13%; vertical-align: middle;">&#160;</td>
          </tr>
          <tr>
            <td nowrap="nowrap" style="width: 6%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div><a href="https://www.sec.gov/Archives/edgar/data/1816431/000114036124010438/ef20015319_ex10-13-3.htm">99.3+</a></div>
            </td>
            <td style="width: 49%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div>Form of Restricted Stock Unit Agreement under 2021 Equity Incentive Plan.</div>
            </td>
            <td style="width: 8%; vertical-align: bottom; background-color: rgb(204, 238, 255);">&#160;</td>
            <td style="width: 13%; vertical-align: bottom; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">Form 10-K</div>
              <div style="text-align: center;">(Exhibit 10.13.3)</div>
            </td>
            <td style="width: 11%; vertical-align: middle; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">2/29/2024</div>
            </td>
            <td style="width: 13%; vertical-align: middle; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">001-39486</div>
            </td>
          </tr>
          <tr>
            <td nowrap="nowrap" rowspan="1" style="width: 6%; vertical-align: top;"><br>
            </td>
            <td rowspan="1" style="width: 49%; vertical-align: top;"><br>
            </td>
            <td rowspan="1" style="width: 8%; vertical-align: bottom;"><br>
            </td>
            <td rowspan="1" style="width: 13%; vertical-align: bottom;"><br>
            </td>
            <td rowspan="1" style="width: 11%; vertical-align: middle;"><br>
            </td>
            <td rowspan="1" style="width: 13%; vertical-align: middle;"><br>
            </td>
          </tr>
          <tr>
            <td nowrap="nowrap" style="width: 6%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div><a href="ef20022562_ex107.htm">107</a></div>
            </td>
            <td style="width: 49%; vertical-align: top; background-color: rgb(204, 238, 255);">
              <div>Filing Fee Table</div>
            </td>
            <td style="width: 8%; vertical-align: bottom; background-color: rgb(204, 238, 255);">
              <div style="text-align: center;">X</div>
            </td>
            <td style="width: 13%; vertical-align: bottom; background-color: rgb(204, 238, 255);">&#160;</td>
            <td style="width: 11%; vertical-align: middle; background-color: rgb(204, 238, 255);">&#160;</td>
            <td style="width: 13%; vertical-align: middle; background-color: rgb(204, 238, 255);">&#160;</td>
          </tr>

      </table>
      <div style="color: #000000;"><br>
        + Denotes management contract or compensatory plan or arrangement</div>
      <div>&#160;</div>
      <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
        <div class="BRPFPageBreak" style="page-break-after: always;">
          <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
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      <div style="text-align: center; font-weight: bold;">SIGNATURES</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt;">Pursuant to the requirements of the Securities Act of 1933, as amended, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form
        S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Branford, State of Connecticut, on February 29, 2024.</div>
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          <tr>
            <td style="width: 50%; vertical-align: top;">&#160;</td>
            <td colspan="2" style="vertical-align: top;">
              <div style="font-weight: bold;">QUANTUM-SI INCORPORATED</div>
            </td>
          </tr>
          <tr>
            <td style="width: 50%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
            <td style="width: 5%; vertical-align: top; padding-bottom: 2px;">
              <div>By:</div>
            </td>
            <td style="width: 45%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
              <div>/s/ Jeffrey Hawkins</div>
            </td>
          </tr>
          <tr>
            <td style="width: 50%; vertical-align: top;">&#160;</td>
            <td style="width: 5%; vertical-align: top;">&#160;</td>
            <td style="width: 45%; vertical-align: top;">
              <div>Jeffrey Hawkins</div>
            </td>
          </tr>
          <tr>
            <td style="width: 50%; vertical-align: top;">&#160;</td>
            <td style="width: 5%; vertical-align: top;">&#160;</td>
            <td style="width: 45%; vertical-align: top;">
              <div>President and Chief Executive Officer</div>
            </td>
          </tr>

      </table>
      <div><br>
      </div>
      <div style="text-align: center; font-weight: bold;"><a name="POWEROFATTORNEY"><!--Anchor--></a>POWER OF ATTORNEY</div>
      <div style="text-align: center; font-weight: bold;"> <br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;">Each person whose signature appears below constitutes and appoints each of Jeffrey Hawkins and Jeffry Keyes, acting alone or together with another attorney-in-fact, as his or her true and lawful
        attorney-in-fact and agent, with full power of substitution and re-substitution, for such person and in his or her name, place and stead, in any and all capacities, to sign any or all further amendments (including post-effective amendments) to this
        registration statement, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and
        authority to do and perform each and every act and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said
        attorney-in-fact and agent, or his or her substitute or substitutes, may lawfully do or cause to be done by virtue hereof.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt;">Pursuant to the requirements of the Securities Act of 1933, as amended, this registration statement has been signed by the following persons in the capacities and on the date indicated.</div>
      <div>&#160;</div>
      <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z73d83ddd743a459298d6aad711cfedb2">

          <tr>
            <td style="width: 38%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center; font-weight: bold;">Signature</div>
            </td>
            <td style="width: 2%; vertical-align: top;">&#160;</td>
            <td style="width: 38%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center; font-weight: bold;">Title</div>
            </td>
            <td style="width: 2%; vertical-align: top;">&#160;</td>
            <td style="width: 20%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center; font-weight: bold;">Date</div>
            </td>
          </tr>
          <tr>
            <td rowspan="1" style="width: 38%; vertical-align: top;"><br>
            </td>
            <td rowspan="1" style="width: 2%; vertical-align: top;">&#160;</td>
            <td rowspan="1" style="width: 38%; vertical-align: middle;"><br>
            </td>
            <td rowspan="1" style="width: 2%; vertical-align: middle;">&#160;</td>
            <td rowspan="1" style="width: 20%; vertical-align: middle;"><br>
            </td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center;">/s/ Jeffrey Hawkins</div>
            </td>
            <td rowspan="2" style="width: 2%; vertical-align: top;"><br>
            </td>
            <td rowspan="2" style="width: 38%; vertical-align: middle;">
              <div style="text-align: center;">President, Chief Executive Officer and Director</div>
              <div style="text-align: center;">(Principal Executive Officer)</div>
            </td>
            <td rowspan="2" style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td rowspan="2" style="width: 20%; vertical-align: middle;">
              <div style="text-align: center;">February 29, 2024</div>
            </td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top;">
              <div style="text-align: center;">Jeffrey Hawkins</div>
            </td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top;"><br>
            </td>
            <td style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td style="width: 38%; vertical-align: middle;">&#160;</td>
            <td style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td style="width: 20%; vertical-align: middle;">&#160;</td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center;">/s/ Jeffry Keyes</div>
            </td>
            <td rowspan="2" style="width: 2%; vertical-align: top;"><br>
            </td>
            <td rowspan="2" style="width: 38%; vertical-align: middle;">
              <div style="text-align: center;">Chief Financial Officer and Treasurer</div>
              <div style="text-align: center;">(Principal Financial and Accounting Officer)</div>
            </td>
            <td rowspan="2" style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td rowspan="2" style="width: 20%; vertical-align: top;">
              <div style="text-align: center;">February 29, 2024</div>
            </td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top;">
              <div style="text-align: center;">Jeffry Keyes</div>
            </td>
          </tr>
          <tr>
            <td rowspan="1" style="width: 38%; vertical-align: top;"><br>
            </td>
            <td rowspan="1" style="width: 2%; vertical-align: top;"><br>
            </td>
            <td rowspan="1" style="width: 38%; vertical-align: middle;">&#160;</td>
            <td rowspan="1" style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td rowspan="1" style="width: 20%; vertical-align: top;">&#160;</td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center;">/s/ Jonathan M. Rothberg, Ph.D.</div>
            </td>
            <td rowspan="2" style="width: 2%; vertical-align: top;"><br>
            </td>
            <td rowspan="2" style="width: 38%; vertical-align: middle;">
              <div style="text-align: center;">Chairman</div>
            </td>
            <td rowspan="2" style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td rowspan="2" style="width: 20%; vertical-align: top;">
              <div style="text-align: center;">February 29, 2024</div>
            </td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top;">
              <div style="text-align: center;">Jonathan M. Rothberg, Ph.D.</div>
            </td>
          </tr>
          <tr>
            <td rowspan="1" style="width: 38%; vertical-align: top;"><br>
            </td>
            <td rowspan="1" style="width: 2%; vertical-align: top;"><br>
            </td>
            <td rowspan="1" style="width: 38%; vertical-align: middle;">&#160;</td>
            <td rowspan="1" style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td rowspan="1" style="width: 20%; vertical-align: top;">&#160;</td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center;">/s/ Scott Mendel</div>
            </td>
            <td rowspan="2" style="width: 2%; vertical-align: top;"><br>
            </td>
            <td rowspan="2" style="width: 38%; vertical-align: middle;">
              <div style="text-align: center;">Director</div>
            </td>
            <td rowspan="2" style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td rowspan="2" style="width: 20%; vertical-align: top;">
              <div style="text-align: center;">February 29, 2024</div>
            </td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top;">
              <div style="text-align: center;">Scott Mendel</div>
            </td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top;"><br>
            </td>
            <td style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td style="width: 38%; vertical-align: middle;">&#160;</td>
            <td style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td style="width: 20%; vertical-align: middle;">&#160;</td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center;">/s/ John Patrick Kenny</div>
            </td>
            <td rowspan="2" style="width: 2%; vertical-align: top;"><br>
            </td>
            <td rowspan="2" style="width: 38%; vertical-align: middle;">
              <div style="text-align: center;">Director</div>
            </td>
            <td rowspan="2" style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td rowspan="2" style="width: 20%; vertical-align: top;">
              <div style="text-align: center;">February 29, 2024</div>
            </td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top;">
              <div style="text-align: center;">John Patrick Kenny</div>
            </td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top;"><br>
            </td>
            <td style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td style="width: 38%; vertical-align: middle;">&#160;</td>
            <td style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td style="width: 20%; vertical-align: middle;">&#160;</td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center;">/s/ Ruth Fattori</div>
            </td>
            <td rowspan="2" style="width: 2%; vertical-align: top;"><br>
            </td>
            <td rowspan="2" style="width: 38%; vertical-align: middle;">
              <div style="text-align: center;">Director</div>
            </td>
            <td rowspan="2" style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td rowspan="2" style="width: 20%; vertical-align: top;">
              <div style="text-align: center;">February 29, 2024</div>
            </td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top;">
              <div style="text-align: center;">Ruth Fattori</div>
            </td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top;">&#160;</td>
            <td style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td style="width: 38%; vertical-align: middle;">&#160;</td>
            <td style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td style="width: 20%; vertical-align: middle;">&#160;</td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center;">/s/ Brigid A. Makes</div>
            </td>
            <td rowspan="2" style="width: 2%; vertical-align: top;"><br>
            </td>
            <td rowspan="2" style="width: 38%; vertical-align: middle;">
              <div style="text-align: center;">Director</div>
            </td>
            <td rowspan="2" style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td rowspan="2" style="width: 20%; vertical-align: top;">
              <div style="text-align: center;">February 29, 2024</div>
            </td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top;">
              <div style="text-align: center;">Brigid A. Makes</div>
            </td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top;"><br>
            </td>
            <td style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td style="width: 38%; vertical-align: middle;">&#160;</td>
            <td style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td style="width: 20%; vertical-align: middle;">&#160;</td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center;">/s/ Kevin Rakin</div>
            </td>
            <td rowspan="2" style="width: 2%; vertical-align: top;"><br>
            </td>
            <td rowspan="2" style="width: 38%; vertical-align: middle;">
              <div style="text-align: center;">Director</div>
            </td>
            <td rowspan="2" style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td rowspan="2" style="width: 20%; vertical-align: top;">
              <div style="text-align: center;">February 29, 2024</div>
            </td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top;">
              <div style="text-align: center;">Kevin Rakin</div>
            </td>
          </tr>
          <tr>
            <td rowspan="1" style="width: 38%; vertical-align: top;"><br>
            </td>
            <td rowspan="1" style="width: 2%; vertical-align: top;"><br>
            </td>
            <td rowspan="1" style="width: 38%; vertical-align: middle;">&#160;</td>
            <td rowspan="1" style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td rowspan="1" style="width: 20%; vertical-align: top;">&#160;</td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center;">/s/ Amir Jafri</div>
            </td>
            <td style="width: 2%; vertical-align: top;"><br>
            </td>
            <td style="width: 38%; vertical-align: middle;">
              <div style="text-align: center;">Director</div>
            </td>
            <td style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td style="width: 20%; vertical-align: top;">
              <div style="text-align: center;">February 29, 2024</div>
            </td>
          </tr>
          <tr>
            <td style="width: 38%; vertical-align: top;">
              <div style="text-align: center;">Amir Jafri</div>
            </td>
            <td style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td style="width: 38%; vertical-align: middle;">&#160;</td>
            <td style="width: 2%; vertical-align: middle;"><br>
            </td>
            <td style="width: 20%; vertical-align: middle;">&#160;</td>
          </tr>

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{"company-data": {"conformed-name": "Quantum-Si Inc", "cik": "0001816431", "assigned-sic": "3829", "organization-name": "08 Industrial Applications and Services", "irs-number": "851388175", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-277533", "film-number": "24704592"}, "business-address": {"street1": "29 BUSINESS PARK DRIVE", "city": "BRANFORD", "state": "CT", "zip": "06405", "phone": "(203) 458-7100"}, "mail-address": {"street1": "29 BUSINESS PARK DRIVE", "city": "BRANFORD", "state": "CT", "zip": "06405"}, "former-company": {"former-conformed-name": "HighCape Capital Acquisition Corp.", "date-changed": "20200629"}}
As filed with the Securities and Exchange Commission on February 29, 2024
Registration No. 333-
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
FORM S-8
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
Quantum-Si Incorporated
(Exact name of registrant as specified in its charter)
Delaware
85-1388175
(State or other jurisdiction of incorporation or organization)
(I.R.S. Employer Identification No.)
29 Business Park Drive
Branford, Connecticut
06405
(Address of Principal Executive Offices)
(Zip Code)
2021 Equity Incentive Plan
(Full title of the plan)
Jeffrey Hawkins
Chief Executive Officer
Quantum-Si Incorporated
29 Business Park Drive
Branford, Connecticut 06405
(Name and address of agent for service)
(866) 688‑7374
(Telephone number, including area code, of agent for service)
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company.
        See the definitions of "large accelerated filer," "accelerated filer," "smaller reporting company," and "emerging growth company" in Rule 12b-2 of the Exchange Act.
Large accelerated filer ☐
Accelerated filer ☐
Non-accelerated filer   ☒
Smaller reporting company ☒
Emerging growth company ☐
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial
        accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐
EXPLANATORY NOTE
This registration statement registers an aggregate of 5,670,796 additional shares of Class A common stock, par value $0.0001 per share, of Quantum-Si Incorporated (the "Registrant") reserved under the Quantum-Si
        Incorporated 2021 Equity Incentive Plan (the "2021 Plan"), representing an increase of 5,670,796 shares reserved under the 2021 Plan effective January 1, 2024 by operation of the 2021 Plan's "evergreen" provision. This registration statement
        registers additional securities of the same class as other securities for which a registration statement filed on Form S-8 (File No. 333-259271) relating to an employee benefit plan is effective. The information contained in the Registrant's
        registration statement on Form S-8 filed with the Securities and Exchange Commission on September 2, 2021 (File No. 333-259271) is hereby incorporated by reference pursuant to General Instruction E of Form S-8.
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 6.
Indemnification of Directors and Officers.
Section 145 of the Delaware General Corporation Law (the "DGCL"), permits a corporation to indemnify its directors and officers against expenses, including attorneys' fees, judgments, fines and
          amounts paid in settlements actually and reasonably incurred by them in connection with any action, suit or proceeding brought by third parties. The directors or officers must have acted in good faith and in a manner they reasonably believed to
          be in or not opposed to the best interests of the corporation and, with respect to any criminal action or proceeding, had no reason to believe their conduct was unlawful. In a derivative action, an action only by or in the right of the
          corporation, indemnification may be made only for expenses, including attorney's fees, actually and reasonably incurred by directors and officers in connection with the defense or settlement of an action or suit, and only with respect to a matter
          as to which they acted in good faith and in a manner they reasonably believed to be in or not opposed to the best interests of the corporation. No indemnification shall be made if such person shall have been adjudged to be liable to the
          corporation, unless and only to the extent that the court in which the action or suit was brought determines upon application that the defendant officers or directors are fairly and reasonably entitled to indemnity for such expenses despite such
          adjudication of liability. The amended and restated certificate of incorporation, as amended, of the registrant provides that the registrant may indemnify its directors, officers, employees or agents to the fullest extent permitted by applicable
          law and the amended and restated bylaws of the registrant provide that the registrant shall indemnify its directors and officers to the fullest extent permitted by applicable law.
Section 102(b)(7) of the DGCL permits a corporation to provide in its certificate of incorporation that a director or officer of the corporation shall not be personally liable to the corporation or
          its stockholders for monetary damages for breach of fiduciary duty as a director or officer, except for liability of (1) a director or officer for any breach of the director's or officer's duty of loyalty to the corporation or its stockholders,
          (2) a director or officer for acts or omissions not in good faith or which involve intentional misconduct or a knowing violation of law, (3) a director for payments of unlawful dividends or unlawful stock purchases or redemptions, (4) a director
          or officer for any transaction from which the director or officer derived an improper personal benefit, or (5) an officer in any action by or in the right of the corporation. The amended and restated certificate of incorporation, as amended, of
          the registrant provides for such limitation of liability with respect to directors and officers of the corporation.
We have entered into indemnification agreements with each of our directors and officers in which we have agreed to indemnify and hold harmless, and also advance expenses as incurred, to the fullest
          extent permitted under applicable law, against all expenses, losses and liabilities incurred by the indemnitee or on the indemnitee's behalf arising from the fact that such person is or was a director, officer, employee or agent of our company or
          our subsidiaries.
The indemnification rights set forth above shall not be exclusive of any other right which an indemnified person may have or hereafter acquire under any statute, our amended and restated certificate
          of incorporation, as amended, our amended and restated bylaws, any agreement, any vote of stockholders or disinterested directors or otherwise.
We maintain standard policies of insurance that provide coverage (1) to our directors and officers against loss rising from claims made by reason of breach of duty or other wrongful act and (2) to
          us with respect to indemnification payments that we may make to such directors and officers.
Item 8.
Exhibits.
Exhibit
Number
Exhibit Description
Filed
Herewith
Incorporated
by Reference
herein from
Form or
Schedule
Filing Date
SEC File/
Reg. Number
4.1
Second Amended and Restated Certificate of Incorporation of the Registrant, as amended.
10-Q
(Exhibit 3.1)
8/7/2023
001-39486
4.2
Amended and Restated Bylaws of the Registrant.
10-K
(Exhibit 3.2)
3/1/2022
001-39486
4.3
Specimen Class A Common Stock Certificate.
S-4/A
(Exhibit 4.1)
5/11/2021
333-253691
4.4
Warrant Agreement, dated as of September 3, 2020, by and between Quantum-Si Incorporated (formerly HighCape Capital Acquisition Corp.) and Continental Stock Transfer & Trust Company.
8-K
(Exhibit 4.1)
9/9/2020
001-39486
5.1
Opinion of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
X
23.1
Consent of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C. (included in opinion of counsel filed as Exhibit 5.1).
X
23.2
Consent of Deloitte & Touche LLP, independent registered public accounting firm.
X
24.1
Power of Attorney (included on the signature page hereof).
X
99.1+
Quantum-Si Incorporated 2021 Equity Incentive Plan.
8-K
(Exhibit 10.13.1)
6/15/2021
001-39486
99.2+
Form of Stock Option Agreement under 2021 Equity Incentive Plan.
8-K
(Exhibit 10.13.2)
6/15/2021
001-39486
99.3+
Form of Restricted Stock Unit Agreement under 2021 Equity Incentive Plan.
Form 10-K
(Exhibit 10.13.3)
2/29/2024
001-39486
107
Filing Fee Table
X
+ Denotes management contract or compensatory plan or arrangement
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, as amended, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form
        S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Branford, State of Connecticut, on February 29, 2024.
QUANTUM-SI INCORPORATED
By:
/s/ Jeffrey Hawkins
Jeffrey Hawkins
President and Chief Executive Officer
POWER OF ATTORNEY
Each person whose signature appears below constitutes and appoints each of Jeffrey Hawkins and Jeffry Keyes, acting alone or together with another attorney-in-fact, as his or her true and lawful
        attorney-in-fact and agent, with full power of substitution and re-substitution, for such person and in his or her name, place and stead, in any and all capacities, to sign any or all further amendments (including post-effective amendments) to this
        registration statement, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and
        authority to do and perform each and every act and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said
        attorney-in-fact and agent, or his or her substitute or substitutes, may lawfully do or cause to be done by virtue hereof.
Pursuant to the requirements of the Securities Act of 1933, as amended, this registration statement has been signed by the following persons in the capacities and on the date indicated.
Signature
Title
Date
/s/ Jeffrey Hawkins
President, Chief Executive Officer and Director
(Principal Executive Officer)
February 29, 2024
Jeffrey Hawkins
/s/ Jeffry Keyes
Chief Financial Officer and Treasurer
(Principal Financial and Accounting Officer)
February 29, 2024
Jeffry Keyes
/s/ Jonathan M. Rothberg, Ph.D.
Chairman
February 29, 2024
Jonathan M. Rothberg, Ph.D.
/s/ Scott Mendel
Director
February 29, 2024
Scott Mendel
/s/ John Patrick Kenny
Director
February 29, 2024
John Patrick Kenny
/s/ Ruth Fattori
Director
February 29, 2024
Ruth Fattori
/s/ Brigid A. Makes
Director
February 29, 2024
Brigid A. Makes
/s/ Kevin Rakin
Director
February 29, 2024
Kevin Rakin
/s/ Amir Jafri
Director
February 29, 2024
Amir Jafri