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    <div style="text-align: center;"><font style="font-weight: bold; color: rgb(0, 0, 0);">As filed with the Securities and Exchange Commission on July 22, 2022<br>
      </font><br>
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    <div style="text-align: right; color: rgb(0, 0, 0); font-weight: bold;">
      <div style="color: rgb(0, 0, 0); font-weight: bold;">Registration No. 333-______</div>
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    <div style="text-align: center; font-weight: bold; font-size: 14pt;">UNITED STATES</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-size: 14pt; font-weight: bold;">SECURITIES AND EXCHANGE COMMISSION</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-size: 12pt; font-weight: bold;">WASHINGTON, D.C. 20549</div>
    <div><br>
    </div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-size: 18pt; font-weight: bold;">FORM S-8</div>
    <div><br>
    </div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">REGISTRATION STATEMENT</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">UNDER</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">THE SECURITIES ACT OF 1933</div>
    <div><br>
    </div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-size: 24pt; font-weight: bold;">ADMA BIOLOGICS, INC.</div>
    <div style="text-align: center; color: rgb(0, 0, 0);">(Exact name of registrant as specified in its charter)</div>
    <div><br>
    </div>
    <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z441141b5910c43aea19df9ffe928da84">

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          <td style="width: 49%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Delaware</div>
          </td>
          <td style="width: 2.42%; vertical-align: top; padding-bottom: 2px;">
            <div style="text-align: justify; color: rgb(0, 0, 0); font-weight: bold;">&#160;&#160;&#160;&#160;</div>
          </td>
          <td style="width: 49%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">56-2590442</div>
          </td>
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          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0);">(State or other jurisdiction of</div>
          </td>
          <td style="width: 2.42%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0);">(I.R.S. Employer Identification No.)</div>
          </td>
        </tr>
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          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0);">incorporation or organization)</div>
          </td>
          <td style="width: 2.42%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">&#160;</td>
        </tr>
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          <td style="width: 49%; vertical-align: top;">&#160;</td>
          <td style="width: 2.42%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">&#160;</td>
        </tr>
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          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">465 State Route 17</div>
          </td>
          <td style="width: 2.42%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">&#160;</td>
        </tr>
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          <td style="width: 49%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Ramsey, New Jersey</div>
          </td>
          <td style="width: 2.42%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
          <td style="width: 49%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">07446</div>
          </td>
        </tr>
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          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0);">(Address of Principal Executive Offices)</div>
          </td>
          <td style="width: 2.42%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0);">(Zip Code)</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">ADMA BIOLOGICS, INC. 2022 EQUITY COMPENSATION PLAN</div>
    <div style="text-align: center; color: rgb(0, 0, 0);">(Full title of the plan)</div>
    <div><br>
    </div>
    <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z8d71ca0839f140e8afa80bb972ee75c2">

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          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Adam S. Grossman&#160;</div>
          </td>
          <td style="width: 2.42%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0);">&#160;&#160;&#160;&#160;</div>
          </td>
          <td style="width: 49%; vertical-align: top;">&#160;</td>
        </tr>
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          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">President and Chief Executive Officer</div>
          </td>
          <td style="width: 2.42%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">David C. Schwartz, Esq.</div>
          </td>
        </tr>
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          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">ADMA Biologics, Inc.</div>
          </td>
          <td style="width: 2.42%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Morgan, Lewis &amp; Bockius LLP</div>
          </td>
        </tr>
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          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">465 State Route 17</div>
          </td>
          <td style="width: 2.42%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">502 Carnegie Center</div>
          </td>
        </tr>
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          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Ramsey, New Jersey 07446</div>
          </td>
          <td style="width: 2.42%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Princeton, New Jersey 08540</div>
          </td>
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          <td style="width: 49%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">(201) 478-5552</div>
          </td>
          <td style="width: 2.42%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">&#160;(609) 919-6600</div>
          </td>
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          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0);">(Name, address, telephone number,</div>
          </td>
          <td style="width: 2.42%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0);">(With copies to)</div>
          </td>
        </tr>
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          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0);">including area code, of agent for service)</div>
          </td>
          <td style="width: 2.42%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">&#160;</td>
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    <div><br>
    </div>
    <div style="text-align: justify; text-indent: 18pt; color: rgb(0, 0, 0);">Indicate by check mark whether the Registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth
      company.&#160; See the definitions of &#8220;large accelerated filer,&#8221; &#8220;accelerated filer,&#8221; &#8220;smaller reporting company,&#8221; and &#8220;emerging growth company&#8221; in Rule 12b-2 of the Exchange Act.</div>
    <div><br>
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          <td style="width: 20%; vertical-align: top;">
            <div style="text-align: center; text-indent: -7.2pt; margin-left: 7.2pt; color: rgb(0, 0, 0);">Large accelerated filer &#9744;</div>
          </td>
          <td style="width: 20%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0);">Accelerated filer &#9744;</div>
          </td>
          <td style="width: 20%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0);">Non-accelerated filer &#9746;</div>
            <div>&#160;</div>
          </td>
          <td style="width: 20%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0);">Smaller reporting company &#9746;</div>
          </td>
          <td style="width: 20.01%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0);">Emerging growth company &#9744;</div>
          </td>
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    </table>
    <div><br>
    </div>
    <div style="text-align: justify; text-indent: 18pt; color: rgb(0, 0, 0);">If an emerging growth company, indicate by check mark if the Registrant has elected not to use the extended transition period for complying with any new or revised financial
      accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act.&#160; &#9744;</div>
    <div><br>
    </div>
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    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">EXPLANATORY NOTE</div>
    <div><br>
    </div>
    <div style="text-align: justify; text-indent: 36pt;">On June 21, 2022 (the &#8220;<u>Effective Date</u>&#8221;), the stockholders of ADMA Biologics, Inc. (the &#8220;<u>Registrant</u>&#8221;) approved the ADMA Biologics, Inc. 2022 Equity Compensation Plan (the &#8220;<u>2022 Plan</u>&#8221;).








      Subject to adjustment, the 2022 Plan authorizes the issuance or transfer of up to 18,000,0000 shares (the &#8220;<u>Base 2022 Plan Shares</u>&#8221;) of the Registrant&#8217;s common stock, $0.0001 par value per share (the &#8220;<u>Common Stock</u>&#8221;). Additionally, the
      2022 Plan authorizes the issuance and transfer of (i) up to 5,714,620 shares of Common Stock, which is the number of shares that remained available for grants under the Amended and Restated ADMA Biologics, Inc. 2014 Omnibus Incentive Compensation
      Plan, as amended (the &#8220;<u>2014 Plan</u>&#8221;) as of the Effective Date and (ii) any shares of Common Stock subject to outstanding grants under the 2014 Plan that terminate, expire or are canceled, forfeited, exchanged or surrendered without having been
      exercised, vested or paid under the 2014 Plan after the Effective Date and that become available for issuance under the 2022 Plan (the shares of Common Stock referred to in clauses (i) and (ii) above, the &#8220;<u>Rollover Shares</u>&#8221;). As disclosed in
      the Registrant&#8217;s Definitive Proxy Statement on Schedule 14A, filed with the Securities and Exchange Commission (the "<font style="font-family: 'Times New Roman', Times, serif;"><u>Commission</u></font>") on April 28, 2022, there were 13,722,164
      shares of Common Stock underlying existing equity awards under the 2014 Plan as of April 15, 2022.</div>
    <div><br>
    </div>
    <div style="text-align: justify; text-indent: 36pt;">The Registrant is filing this Registration Statement on Form S-8 to register the Base 2022 Plan Shares. The Registrant is concurrently filing post-effective amendments to certain of the Registrant&#8217;s
      previously filed registration statements on Form S&#8209;8 with respect to the Rollover Shares.</div>
    <div><br>
    </div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">PART I</div>
    <div><br>
    </div>
    <div style="text-align: center; font-weight: bold;">INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS</div>
    <div>&#160;</div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z42a2abcc030a4f96bd764c16c99b0b00">

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          <td style="width: 54pt; vertical-align: top; font-weight: bold;">Item 1.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-weight: bold;">Plan Information.*</div>
          </td>
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    </table>
    <div>&#160;</div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zd6d5f83c637d4ee683d404d64ed062c0">

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          <td style="width: 54pt; vertical-align: top; font-weight: bold;">Item 2.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-weight: bold;">Registrant Information and Employee Plan Annual Information.*</div>
          </td>
        </tr>

    </table>
    <div style="text-align: justify;">&#160;&#160;&#160;&#160; <br>
      <hr noshade="noshade" align="left" style="background-color: #000000; border-bottom: medium none; border-left: medium none; border-right: medium none; border-top: medium none; margin: 0px auto 0px 0px; height: 2px; width: 10%; color: #000000; text-align: left;"></div>
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          <td style="width: 9pt; vertical-align: top;">*</td>
          <td style="width: auto; vertical-align: top;">
            <div>The documents containing the information specified in Part I will be delivered in accordance with Rule 428(b)(1) under the Securities Act of 1933, as amended (the &#8220;<u>Securities Act</u>&#8221;). Such documents are not required to be, and are
              not, filed with the Commission either as part of this Registration Statement or as prospectuses or prospectus supplements pursuant to Rule 424 under the Securities Act. These documents, and the documents incorporated by reference in this
              Registration Statement pursuant to Item 3 of Part II of this Form S-8, taken together, constitute a prospectus that meets the requirements of Section 10(a) of the Securities Act.&#160;</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div style="text-align: center; font-weight: bold;">PART II</div>
    <div>&#160;</div>
    <div style="text-align: center; font-weight: bold;">INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</div>
    <div>&#160;</div>
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          <td style="width: 54pt; vertical-align: top; font-weight: bold;">Item 3.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-weight: bold;">Incorporation of Documents by Reference.</div>
          </td>
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    </table>
    <div>&#160;</div>
    <div style="text-align: justify; text-indent: 36pt;">The following documents, which have been previously filed by the <font style="color: rgb(0, 0, 0);">Registrant</font> with the Commission pursuant to the Securities Exchange Act of 1934, as amended
      (the &#8220;<u>Exchange Act</u>&#8221;) are hereby incorporated herein by reference and shall be deemed to be a part of this Registration Statement:</div>
    <div><br>
    </div>
    <div>
      <div>
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                <td style="width: 18pt;">&#160;</td>
                <td style="vertical-align: top; width: 27pt;">
                  <div style="text-align: justify;">(1)</div>
                </td>
                <td style="align: left; vertical-align: top; width: auto;">
                  <div style="text-align: justify;">The <font style="color: rgb(0, 0, 0);">Registrant&#8217;s</font> Annual Report on Form 10-K for the year ended December 31, 2021, filed with the Commission on <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1368514/000114036122011030/brhc10035480_10k.htm">March 24, 2022</a> (including the portions of the Registrant's Definitive Proxy Statement on Schedule 14A filed with the Commission
                    on <a href="https://www.sec.gov/Archives/edgar/data/1368514/000114036122016578/ny20003524x2_def14a.htm">April 28, 2022</a> that are incorporated by reference therein);</div>
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    </div>
    <div><br>
    </div>
    <div>
      <div>
        <div>
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                <td style="width: 18pt;">&#160;</td>
                <td style="vertical-align: top; width: 27pt;">
                  <div style="text-align: justify;">(2)</div>
                </td>
                <td style="align: left; vertical-align: top; width: auto;">
                  <div style="text-align: justify;">The Registrant&#8217;s Quarterly Report on Form 10-Q for the quarter ended March 31, 2022, filed with the Commission on <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1368514/000114036122018668/brhc10037445_10q.htm">May 11, 2022</a>;&#160;</div>
                </td>
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    </div>
    <div><br>
    </div>
    <div>
      <div>
        <div>
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                <td style="width: 18pt;">&#160;</td>
                <td style="vertical-align: top; width: 27pt;">
                  <div style="text-align: justify;">(3)</div>
                </td>
                <td style="align: left; vertical-align: top; width: auto;">
                  <div style="text-align: justify;">The <font style="color: rgb(0, 0, 0);">Registrant&#8217;s Current Reports on Form 8-K filed with the Commission on <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1368514/000114036122001782/brhc10032849_8k.htm">January 18, 2022</a>, <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1368514/000114036122008174/brhc10034851_8k.htm">March






                        7, 2022</a>, <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1368514/000114036122008654/brhc10035009_8k.htm">March 9, 2022</a>, <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1368514/000114036122011213/brhc10035702_8k.htm">March 25, 2022</a>, <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1368514/000114036122022769/brhc10038698_8k.htm">June
                        13, 2022</a>, <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1368514/000114036122023666/brhc10038967_8k.htm">June 21, 2022</a> and <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1368514/000114036122024139/brhc10039148_8k.htm">June 27, 2022</a> (provided that any portions of such reports that are deemed furnished and not filed </font>pursuant to
                    instructions to Form 8-K shall not be incorporated by reference into this Registration Statement); and</div>
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              <div>(4)</div>
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            <td style="width: auto; vertical-align: top;">
              <div style="text-align: justify;">The description of Common Stock set forth in Exhibit 4.11 to the <font style="color: rgb(0, 0, 0);">Registrant&#8217;s</font> Annual Report on Form 10-K filed with the Commission on <a href="https://www.sec.gov/Archives/edgar/data/1368514/000114036122011030/brhc10035480_ex4-11.htm">March 24, 2022</a> pursuant to Section 12(b) of the Exchange Act, including any amendment or report filed for the purpose of updating such
                description.</div>
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    </div>
    <div style="text-align: justify; text-indent: 36pt;">In addition, all documents that the <font style="color: rgb(0, 0, 0);">Registrant</font> files pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act subsequent to the effective date of
      this Registration Statement (except for any portions of the <font style="color: rgb(0, 0, 0);">Registrant&#8217;s</font> Current Reports on Form 8-K furnished pursuant to Item 2.02 or Item 7.01 thereof and any corresponding exhibits thereto not filed with
      the Commission), but prior to the filing of a post-effective amendment to this Registration Statement indicating that all securities offered hereby have been sold or which deregisters all securities then remaining unsold shall be deemed to be
      incorporated by reference in this Registration Statement and to be a part hereof from the date of filing such documents.</div>
    <div><br>
    </div>
    <div style="text-align: justify; text-indent: 36pt;">For purposes of this Registration Statement, any document or statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or
      superseded to the extent that a statement contained herein or in any other subsequently filed document which also is or is deemed to be incorporated by reference herein modifies or supersedes such document or statement in such document. Any such
      statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this Registration Statement.</div>
    <div><br>
    </div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z28d9095c05ad4153a22a1c69e32b69f9">

        <tr>
          <td style="width: 54pt; vertical-align: top; font-weight: bold;">Item 4.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-weight: bold;">Description of Securities.</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div style="text-align: justify; text-indent: 36pt;">Not applicable.</div>
    <div><br>
    </div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z7ddb411fd8084092bd7bc590283d81a5">

        <tr>
          <td style="width: 54pt; vertical-align: top; font-weight: bold;">Item 5.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-weight: bold;">Interests of Named Experts and Counsel.</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div style="text-align: justify; text-indent: 36pt;">Not applicable.</div>
    <div><br>
    </div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z97fe9fd1ebe14e859018a40cb027fff5">

        <tr>
          <td style="width: 54pt; vertical-align: top; font-weight: bold;">Item 6.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-weight: bold;">Indemnification of Directors and Officers.</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div style="text-align: justify; text-indent: 36pt;">Section 145 of the DGCL provides, generally, that a corporation shall have the power to indemnify any person who was or is a party or is threatened to be made a party to any threatened, pending or
      completed action, suit or proceeding, whether civil, criminal, administrative or investigative (other than an action by or in the right of the corporation) by reason of the fact that such person is or was a director, officer, employee or agent of the
      corporation against all expenses, judgments, fines and amounts paid in settlement actually and reasonably incurred by such person in connection with such action, suit or proceeding if such person acted in good faith and in a manner such person
      reasonably believed to be in or not opposed to the best interests of the corporation and, with respect to any criminal action or proceeding, had no reasonable cause to believe his or her conduct was unlawful. A corporation may similarly indemnify
      such person for expenses actually and reasonably incurred by such person in connection with the defense or settlement of any action or suit by or in the right of the corporation, provided that such person acted in good faith and in a manner he or she
      reasonably believed to be in or not opposed to the best interests of the corporation, and, in the case of claims, issues and matters as to which such person shall have been adjudged liable to the corporation, provided that a court shall have
      determined, upon application, that, despite the adjudication of liability but in view of all of the circumstances of the case, such person is fairly and reasonably entitled to indemnity for such expenses which such court shall deem proper.</div>
    <div>&#160;</div>
    <div style="text-align: justify; text-indent: 36pt;">In accordance with Section 102(b)(7) of the DGCL, the Registrant&#8217;s Second Amended and Restated Certificate of Incorporation, as amended (the &#8220;<u>Charter</u>&#8221;) provides that a director will not be
      personally liable to the Registrant or its stockholders for monetary damages for breach of fiduciary duty as a director, except to the extent such exemption from liability or limitation thereof is not permitted under the DGCL. No such provision shall
      eliminate or limit the liability of a director for any act or omission occurring prior to the date when such provision became effective. Accordingly, these provisions will have no effect on the availability of equitable remedies such as an injunction
      or rescission based on a director&#8217;s breach of his or her duty of care.</div>
    <div>&#160;</div>
    <div style="text-align: justify; text-indent: 36pt;">The Charter provides that the Registrant will indemnify its present and former directors and officers to the maximum extent permitted by the DGCL and that such indemnification will not be exclusive
      of any other rights to which those seeking indemnification may have or hereafter acquire under any statute, provision of the Charter, the Registrant&#8217;s bylaws, agreement, vote of stockholders or disinterested directors or otherwise.</div>
    <div>&#160;</div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
      <div style="page-break-after:always;" id="DSPFPageBreak">
        <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
    </div>
    <div style="text-align: justify; text-indent: 36pt;">The Registrant has entered into, and expects to continue to enter into, customary indemnification arrangements with each of its current directors and executive officers. These arrangements require
      the Registrant to indemnify these individuals to the fullest extent permitted under Delaware law against liabilities that may arise by reason of their service to the Registrant, and to advance expenses incurred as a result of any proceeding against
      them as to which they could be indemnified. The Registrant also intends to enter into indemnification arrangements with future directors and executive officers.</div>
    <div>&#160;</div>
    <div style="text-align: justify; text-indent: 36pt;">See also the undertakings set out in response to Item 9 hereof.</div>
    <div>&#160;</div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zcf10d788e8134a0eb63d0bfc7a01c2d1">

        <tr>
          <td style="width: 54pt; vertical-align: top; font-weight: bold;">Item 7.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-weight: bold;">Exemption from Registration Claimed.</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div>&#160;&#160;<font class="HorizontalTab" style="width: 9pt; font-size: 1px; display: inline-block;">&#160;&#160;&#160; &#160; </font>Not applicable.</div>
    <div>&#160;</div>
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        <tr>
          <td style="width: 54pt; vertical-align: top; font-weight: bold;">Item 8.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-weight: bold;">Exhibits.</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div style="text-align: justify;">&#160;&#160; <font class="HorizontalTab" style="width: 9pt; font-size: 1px; display: inline-block;">&#160;&#160;&#160;&#160;</font>The Registrant hereby files the exhibits set forth below:</div>
    <div><br>
    </div>
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        <tr>
          <td style="width: 9%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="text-align: center; text-indent: -2.7pt; margin-left: 7.2pt; color: rgb(0, 0, 0); font-weight: bold;">Exhibit Number</div>
          </td>
          <td style="width: 1%; vertical-align: bottom;">&#160;</td>
          <td style="width: 90%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Description of Exhibit</div>
          </td>
        </tr>
        <tr>
          <td style="width: 9%; vertical-align: top;">&#160;</td>
          <td style="width: 1%; vertical-align: top;">&#160;</td>
          <td style="width: 90%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 9%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify; text-indent: -7.2pt; margin-left: 7.2pt; color: rgb(0, 0, 0);"><a href="https://www.sec.gov/Archives/edgar/data/1368514/000119380519000774/e618626_ex3-1.htm">4.1</a></div>
          </td>
          <td style="width: 1%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
          <td style="width: 90%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify; color: rgb(0, 0, 0);">Second Amended and Restated Certificate of Incorporation of the ADMA Biologics, Inc. (incorporated herein by reference to Exhibit 3.1 to the Registrant&#8217;s Current Report on Form 8-K, filed
              with the Commission on August 23, 2019).</div>
          </td>
        </tr>
        <tr>
          <td style="width: 9%; vertical-align: top;">&#160;</td>
          <td style="width: 1%; vertical-align: top;">&#160;</td>
          <td style="width: 90%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 9%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify; text-indent: -7.2pt; margin-left: 7.2pt; color: rgb(0, 0, 0);"><a href="https://www.sec.gov/Archives/edgar/data/1368514/000119380521000749/e620651_ex3-1.htm">4.2</a></div>
          </td>
          <td style="width: 1%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
          <td style="width: 90%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify; color: rgb(0, 0, 0);">Certificate of Amendment of the Second Amended and Restated Certificate of Incorporation of ADMA Biologics, Inc., dated as of May 27, 2021 (incorporated by reference to Exhibit 3.1 to the
              Registrant&#8217;s Current Report on Form 8-K filed with the Commission on May 28, 2021).</div>
          </td>
        </tr>
        <tr>
          <td style="width: 9%; vertical-align: top;">&#160;</td>
          <td style="width: 1%; vertical-align: top;">&#160;</td>
          <td style="width: 90%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 9%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify; text-indent: -7.2pt; margin-left: 7.2pt; color: rgb(0, 0, 0);"><a href="https://www.sec.gov/Archives/edgar/data/1368514/000119380516004084/e615468_ex3-1.htm">4.3</a></div>
          </td>
          <td style="width: 1%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
          <td style="width: 90%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify; color: rgb(0, 0, 0);">Amended and Restated Bylaws (incorporated herein by reference to Exhibit 3.1 to the Registrant&#8217;s Current Report on Form 8-K, filed with the Commission on October 7, 2016).</div>
          </td>
        </tr>
        <tr>
          <td style="width: 9%; vertical-align: top;">&#160;</td>
          <td style="width: 1%; vertical-align: top;">&#160;</td>
          <td style="width: 90%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 9%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify; text-indent: -7.2pt; margin-left: 7.2pt; color: rgb(0, 0, 0);"><a href="brhc10039578_ex5-1.htm">5.1</a></div>
          </td>
          <td style="width: 1%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
          <td style="width: 90%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify; color: rgb(0, 0, 0);">Opinion of Morgan, Lewis and Bockius LLP, counsel for the Registrant, regarding the legal validity of the shares of Common Stock being registered on this Registration Statement (filed
              herewith).</div>
          </td>
        </tr>
        <tr>
          <td style="width: 9%; vertical-align: top;" rowspan="1">&#160;</td>
          <td style="width: 1%; vertical-align: top;" rowspan="1">&#160;</td>
          <td style="width: 90%; vertical-align: top;" rowspan="1">&#160;</td>
        </tr>
        <tr>
          <td style="width: 9%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify; text-indent: -7.2pt; margin-left: 7.2pt; color: rgb(0, 0, 0);"><a href="https://www.sec.gov/Archives/edgar/data/1368514/000114036122023666/brhc10038967_ex10-1.htm">10.1</a></div>
          </td>
          <td style="width: 1%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
          <td style="width: 90%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify; color: rgb(0, 0, 0);">ADMA Biologics, Inc. 2022 Equity Compensation Plan (incorporated herein by reference to Exhibit 10.1 to the Registrant&#8217;s Current Report on Form 8-K filed with the Commission on June 21,
              2022).</div>
          </td>
        </tr>
        <tr>
          <td style="width: 9%; vertical-align: top;">&#160;</td>
          <td style="width: 1%; vertical-align: top;">&#160;</td>
          <td style="width: 90%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 9%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify; text-indent: -7.2pt; margin-left: 7.2pt; color: rgb(0, 0, 0);"><a href="brhc10039578_ex5-1.htm">23.1</a></div>
          </td>
          <td style="width: 1%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
          <td style="width: 90%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify; color: rgb(0, 0, 0);">Consent of Morgan, Lewis and Bockius LLP (contained in Exhibit 5.1).</div>
          </td>
        </tr>
        <tr>
          <td style="width: 9%; vertical-align: top;">&#160;</td>
          <td style="width: 1%; vertical-align: top;">&#160;</td>
          <td style="width: 90%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 9%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify; text-indent: -7.2pt; margin-left: 7.2pt; color: rgb(0, 0, 0);"><a href="brhc10039578_ex23-2.htm">23.2</a></div>
          </td>
          <td style="width: 1%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
          <td style="width: 90%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify;">Consent of CohnReznick LLP, the Registrant&#8217;s Independent Registered Public Accounting Firm <font style="color: rgb(0, 0, 0);">(filed herewith).</font></div>
          </td>
        </tr>
        <tr>
          <td style="width: 9%; vertical-align: top;" rowspan="1">&#160;</td>
          <td style="width: 1%; vertical-align: top;" rowspan="1">&#160;</td>
          <td style="width: 90%; vertical-align: top;" rowspan="1">&#160;</td>
        </tr>
        <tr>
          <td style="width: 9%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify; text-indent: -7.2pt; margin-left: 7.2pt; color: rgb(0, 0, 0);"><a href="#SIGNATURES">24.1</a></div>
          </td>
          <td style="width: 1%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
          <td style="width: 90%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify;">Power of Attorney (included on signature page).</div>
          </td>
        </tr>
        <tr>
          <td style="width: 9%; vertical-align: top;" rowspan="1">&#160;</td>
          <td style="width: 1%; vertical-align: top;" rowspan="1">&#160;</td>
          <td style="width: 90%; vertical-align: top;" rowspan="1">&#160;</td>
        </tr>
        <tr>
          <td style="width: 9%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify; text-indent: -7.2pt; margin-left: 7.2pt; color: rgb(0, 0, 0);"><a href="brhc10039578_ex107.htm">107</a></div>
          </td>
          <td style="width: 1%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
          <td style="width: 90%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify;">Filing Fee Exhibit</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z61695a64eb274d37b02c0395b7fe7fbd">

        <tr>
          <td style="width: 54pt; vertical-align: top; font-weight: bold;">Item 9.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-weight: bold;">Undertakings.</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div>
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          <tr>
            <td style="width: 18pt; vertical-align: top;">
              <div style="color: rgb(0, 0, 0);">(a)</div>
            </td>
            <td style="vertical-align: top;">
              <div style="color: rgb(0, 0, 0);">The undersigned Registrant hereby undertakes:</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <div><br>
      </div>
      <div>
        <div>
          <table cellspacing="0" cellpadding="0" style="width: 100%; font-family: 'Times New Roman'; font-size: 10pt;" id="z76313b6fe329413998d1c2bcd826f280" class="DSPFListTable">

              <tr style="vertical-align: top;">
                <td style="width: 18pt;">&#160;</td>
                <td style="vertical-align: top; width: 27pt;">
                  <div style="color: rgb(0, 0, 0);"><font style="text-align: right; color: rgb(0, 0, 0);">1.</font></div>
                </td>
                <td style="align: left; vertical-align: top; width: auto;">
                  <div style="color: rgb(0, 0, 0);">To file, during any period in which offers or sales are being made, a post-effective amendment to this registration statement:</div>
                </td>
              </tr>

          </table>
        </div>
      </div>
    </div>
    <div>
      <div><br>
      </div>
      <div>
        <div>
          <table cellspacing="0" cellpadding="0" style="width: 100%; font-family: 'Times New Roman'; font-size: 10pt;" id="z4cdb7d9ecc3c435ba2bd5c80c7a21e49" class="DSPFListTable">

              <tr style="vertical-align: top;">
                <td style="width: 45pt;">&#160;</td>
                <td style="vertical-align: top; width: 27pt;">
                  <div style="color: rgb(0, 0, 0);"><font style="text-align: right; color: rgb(0, 0, 0);">i.</font></div>
                </td>
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                  <div style="color: rgb(0, 0, 0);">To include any prospectus required by Section&#160;10(a)(3) of the Securities Act;</div>
                </td>
              </tr>

          </table>
        </div>
      </div>
    </div>
    <div>
      <div><br>
      </div>
    </div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
      <div style="page-break-after:always;" id="DSPFPageBreak">
        <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
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    <div>
      <div>
        <div>
          <table cellspacing="0" cellpadding="0" style="width: 100%; font-family: 'Times New Roman'; font-size: 10pt;" id="zdc2e5e5e063041bfb7381e9a5b9d87cf" class="DSPFListTable">

              <tr style="vertical-align: top;">
                <td style="width: 45pt;">&#160;</td>
                <td style="vertical-align: top; width: 27pt;">
                  <div style="color: rgb(0, 0, 0);"><font style="text-align: right; color: rgb(0, 0, 0);">ii.</font></div>
                </td>
                <td style="align: left; vertical-align: top; width: auto;">
                  <div style="color: rgb(0, 0, 0);">To reflect in the prospectus any facts or events arising after the effective date of the registration statement (or the most recent post-effective amendment thereof) which, individually or in the
                    aggregate, represent a fundamental change in the information set forth in the registration statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities
                    offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in
                    the aggregate, the changes in volume and price represent no more than a 20% change in the maximum aggregate offering price set forth in the &#8220;Calculation of Registration Fee&#8221; table in the effective registration statement.</div>
                </td>
              </tr>

          </table>
        </div>
      </div>
    </div>
    <div>
      <div><br>
      </div>
      <div>
        <div>
          <table cellspacing="0" cellpadding="0" style="width: 100%; font-family: 'Times New Roman'; font-size: 10pt;" id="z3129c0802fb34053a61ff5942366bc31" class="DSPFListTable">

              <tr style="vertical-align: top;">
                <td style="width: 45pt;">&#160;</td>
                <td style="vertical-align: top; width: 27pt;">
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                </td>
                <td style="align: left; vertical-align: top; width: auto;">
                  <div style="color: rgb(0, 0, 0);">To include any material information with respect to the plan of distribution not previously disclosed in the registration statement or any material change to such information in the registration
                    statement;</div>
                </td>
              </tr>

          </table>
        </div>
      </div>
    </div>
    <div>
      <div><br>
      </div>
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    <div>
      <div style="text-align: justify; color: rgb(0, 0, 0);"><font style="font-style: italic;">Provided, however,</font>&#160;that paragraphs (a)(i) and (a)(ii) do not apply if the information required to be included in a post-effective amendment by those
        paragraphs is contained in reports filed with or furnished to the Commission by the Registrant pursuant to Section&#160;13 or Section&#160;15(d) of the Exchange Act that are incorporated by reference in the registration statement.</div>
      <div><br>
      </div>
    </div>
    <div>
      <div>
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            <tr style="vertical-align: top;">
              <td style="width: 18pt;">&#160;</td>
              <td style="vertical-align: top; width: 27pt;">
                <div style="color: rgb(0, 0, 0);"><font style="color: rgb(0, 0, 0);">2.</font></div>
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                <div style="color: rgb(0, 0, 0);">That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered herein,
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                  <div style="color: rgb(0, 0, 0);">To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.</div>
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      <div><br>
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                  <div style="color: rgb(0, 0, 0);">That, for the purpose of determining liability of the Registrant under the Securities Act to any purchaser in the initial distribution of the securities, the undersigned Registrant undertakes that in a
                    primary offering of securities of the undersigned Registrant pursuant to this registration statement, regardless of the underwriting method used to sell the securities to the purchaser, if the securities are offered or sold to such
                    purchaser by means of any of the following communications, the undersigned Registrant will be a seller to the purchaser and will be considered to offer or sell such securities to such purchaser:</div>
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                  <div style="color: rgb(0, 0, 0);">Any preliminary prospectus or prospectus of the undersigned Registrant relating to the offering required to be filed pursuant to Rule 424,</div>
                </td>
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      <div><br>
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                  <div style="color: rgb(0, 0, 0);">Any free writing prospectus relating to the offering prepared by or on behalf of the undersigned Registrant or used or referred to by the undersigned Registrant,</div>
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                  <div style="color: rgb(0, 0, 0);">The portion of any other free writing prospectus relating to the offering containing material information about the undersigned Registrant or its securities provided by or on behalf of the undersigned
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                  <div style="color: rgb(0, 0, 0);">Any other communication that is an offer in the offering made by the undersigned Registrant to the purchaser.</div>
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                  <div style="color: rgb(0, 0, 0);">That, for purposes of determining any liability under the Securities Act, each filing of the Registrant&#8217;s annual report pursuant to Section&#160;13(a) or Section&#160;15(d) of the Exchange Act (and, where
                    applicable, each filing of an employee benefit plan&#8217;s annual report pursuant to Section&#160;15(d) of the Exchange Act) that is incorporated by reference in the Registration Statement shall be deemed to be a new registration statement
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              <div style="color: rgb(0, 0, 0);">(b)</div>
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              <div style="color: rgb(0, 0, 0);">Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the Registrant pursuant to the foregoing provisions, or
                otherwise, the Registrant has been advised that in the opinion of the Commission such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for
                indemnification against such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is
                asserted by such director, officer or controlling person in connection with the securities being registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court
                of appropriate jurisdiction the question whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.</div>
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    <div style="text-align: center; font-weight: bold;">SIGNATURES<a name="SIGNATURES"><!--Anchor--></a></div>
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    <div style="text-align: justify; text-indent: 36pt;">Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8
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            <div style="text-align: justify; color: rgb(0, 0, 0); font-weight: bold;">ADMA Biologics, Inc.</div>
            <div style="text-align: justify; color: rgb(0, 0, 0);">(Registrant)</div>
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          <td style="width: 50%; vertical-align: top;">&#160;</td>
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            <div style="color: rgb(0, 0, 0);">By:</div>
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            <div style="color: rgb(0, 0, 0);">/s/ Brian Lenz</div>
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    <div style="text-align: center; font-weight: bold;">POWER OF ATTORNEY</div>
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    <div style="text-align: justify; text-indent: 36pt;">KNOW BY ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Adam S. Grossman and Brian Lenz, and each of them, the undersigned&#8217;s true and lawful
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    <div style="text-align: justify; text-indent: 36pt;">Pursuant to the requirements of the Securities Act, this Registration Statement has been signed below by the following persons on behalf of the Registrant and in the capacities indicated on the date
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            <div>Executive Vice President and Chief Financial Officer</div>
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          <td style="width: 32%; vertical-align: top;">
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 45%; vertical-align: top;">
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 19%; vertical-align: top;">&#160;</td>
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 19%; vertical-align: top;">&#160;</td>
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          <td style="width: 32%; vertical-align: top;">
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          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 19%; vertical-align: top;">&#160;</td>
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            <div style="text-align: justify;">July 22, 2022</div>
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            <div style="text-align: justify; margin-left: 9pt;">Lawrence P. Guiheen</div>
          </td>
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            <div>/s/ Young T. Kwon</div>
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            <div style="text-align: justify;">Director</div>
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            <div style="text-align: justify;">July 22, 2022</div>
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          <td style="width: 32%; vertical-align: top;">
            <div style="text-align: justify; margin-left: 9pt;">Young T. Kwon</div>
          </td>
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{"company-data": {"conformed-name": "ADMA BIOLOGICS, INC.", "cik": "0001368514", "assigned-sic": "2836", "irs-number": "562590442", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-266291", "film-number": "221100259"}, "business-address": {"street1": "C/O ADMA BIOLOGICS, INC.", "street2": "465 STATE ROUTE 17", "city": "RAMSEY", "state": "NJ", "zip": "07446", "phone": "(201) 478-5552"}, "mail-address": {"street1": "C/O ADMA BIOLOGICS, INC.", "street2": "465 STATE ROUTE 17", "city": "RAMSEY", "state": "NJ", "zip": "07446"}, "former-company": {"former-conformed-name": "R&R ACQUISITION VI, INC", "date-changed": "20060707"}}
As filed with the Securities and Exchange Commission on July 22, 2022
Registration No. 333-______
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
FORM S-8
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
ADMA BIOLOGICS, INC.
(Exact name of registrant as specified in its charter)
Delaware
56-2590442
(State or other jurisdiction of
(I.R.S. Employer Identification No.)
incorporation or organization)
465 State Route 17
Ramsey, New Jersey
07446
(Address of Principal Executive Offices)
(Zip Code)
ADMA BIOLOGICS, INC. 2022 EQUITY COMPENSATION PLAN
(Full title of the plan)
Adam S. Grossman
President and Chief Executive Officer
David C. Schwartz, Esq.
ADMA Biologics, Inc.
Morgan, Lewis & Bockius LLP
465 State Route 17
502 Carnegie Center
Ramsey, New Jersey 07446
Princeton, New Jersey 08540
(201) 478-5552
(609) 919-6600
(Name, address, telephone number,
(With copies to)
including area code, of agent for service)
Indicate by check mark whether the Registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth
      company.  See the definitions of "large accelerated filer," "accelerated filer," "smaller reporting company," and "emerging growth company" in Rule 12b-2 of the Exchange Act.
Large accelerated filer ☐
Accelerated filer ☐
Non-accelerated filer ☒
Smaller reporting company ☒
Emerging growth company ☐
If an emerging growth company, indicate by check mark if the Registrant has elected not to use the extended transition period for complying with any new or revised financial
      accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act.  ☐
EXPLANATORY NOTE
On June 21, 2022 (the "
Effective Date
"), the stockholders of ADMA Biologics, Inc. (the "
Registrant
") approved the ADMA Biologics, Inc. 2022 Equity Compensation Plan (the "
2022 Plan
").

      Subject to adjustment, the 2022 Plan authorizes the issuance or transfer of up to 18,000,0000 shares (the "
Base 2022 Plan Shares
") of the Registrant's common stock, $0.0001 par value per share (the "
Common Stock
"). Additionally, the
      2022 Plan authorizes the issuance and transfer of (i) up to 5,714,620 shares of Common Stock, which is the number of shares that remained available for grants under the Amended and Restated ADMA Biologics, Inc. 2014 Omnibus Incentive Compensation
      Plan, as amended (the "
2014 Plan
") as of the Effective Date and (ii) any shares of Common Stock subject to outstanding grants under the 2014 Plan that terminate, expire or are canceled, forfeited, exchanged or surrendered without having been
      exercised, vested or paid under the 2014 Plan after the Effective Date and that become available for issuance under the 2022 Plan (the shares of Common Stock referred to in clauses (i) and (ii) above, the "
Rollover Shares
"). As disclosed in
      the Registrant's Definitive Proxy Statement on Schedule 14A, filed with the Securities and Exchange Commission (the "
Commission
") on April 28, 2022, there were 13,722,164
      shares of Common Stock underlying existing equity awards under the 2014 Plan as of April 15, 2022.
The Registrant is filing this Registration Statement on Form S-8 to register the Base 2022 Plan Shares. The Registrant is concurrently filing post-effective amendments to certain of the Registrant's
      previously filed registration statements on Form S‑8 with respect to the Rollover Shares.
PART I
INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS
Item 1.
Plan Information.*
Item 2.
Registrant Information and Employee Plan Annual Information.*
*
The documents containing the information specified in Part I will be delivered in accordance with Rule 428(b)(1) under the Securities Act of 1933, as amended (the "
Securities Act
"). Such documents are not required to be, and are
              not, filed with the Commission either as part of this Registration Statement or as prospectuses or prospectus supplements pursuant to Rule 424 under the Securities Act. These documents, and the documents incorporated by reference in this
              Registration Statement pursuant to Item 3 of Part II of this Form S-8, taken together, constitute a prospectus that meets the requirements of Section 10(a) of the Securities Act.
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 3.
Incorporation of Documents by Reference.
The following documents, which have been previously filed by the
Registrant
with the Commission pursuant to the Securities Exchange Act of 1934, as amended
      (the "
Exchange Act
") are hereby incorporated herein by reference and shall be deemed to be a part of this Registration Statement:
(1)
The
Registrant's
Annual Report on Form 10-K for the year ended December 31, 2021, filed with the Commission on
March 24, 2022
(including the portions of the Registrant's Definitive Proxy Statement on Schedule 14A filed with the Commission
                    on
April 28, 2022
that are incorporated by reference therein);
(2)
The Registrant's Quarterly Report on Form 10-Q for the quarter ended March 31, 2022, filed with the Commission on
May 11, 2022
;
(3)
The
Registrant's Current Reports on Form 8-K filed with the Commission on
January 18, 2022
,
March

                        7, 2022
,
March 9, 2022
,
March 25, 2022
,
June
                        13, 2022
,
June 21, 2022
and
June 27, 2022
(provided that any portions of such reports that are deemed furnished and not filed
pursuant to
                    instructions to Form 8-K shall not be incorporated by reference into this Registration Statement); and
(4)
The description of Common Stock set forth in Exhibit 4.11 to the
Registrant's
Annual Report on Form 10-K filed with the Commission on
March 24, 2022
pursuant to Section 12(b) of the Exchange Act, including any amendment or report filed for the purpose of updating such
                description.
In addition, all documents that the
Registrant
files pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act subsequent to the effective date of
      this Registration Statement (except for any portions of the
Registrant's
Current Reports on Form 8-K furnished pursuant to Item 2.02 or Item 7.01 thereof and any corresponding exhibits thereto not filed with
      the Commission), but prior to the filing of a post-effective amendment to this Registration Statement indicating that all securities offered hereby have been sold or which deregisters all securities then remaining unsold shall be deemed to be
      incorporated by reference in this Registration Statement and to be a part hereof from the date of filing such documents.
For purposes of this Registration Statement, any document or statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or
      superseded to the extent that a statement contained herein or in any other subsequently filed document which also is or is deemed to be incorporated by reference herein modifies or supersedes such document or statement in such document. Any such
      statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this Registration Statement.
Item 4.
Description of Securities.
Not applicable.
Item 5.
Interests of Named Experts and Counsel.
Not applicable.
Item 6.
Indemnification of Directors and Officers.
Section 145 of the DGCL provides, generally, that a corporation shall have the power to indemnify any person who was or is a party or is threatened to be made a party to any threatened, pending or
      completed action, suit or proceeding, whether civil, criminal, administrative or investigative (other than an action by or in the right of the corporation) by reason of the fact that such person is or was a director, officer, employee or agent of the
      corporation against all expenses, judgments, fines and amounts paid in settlement actually and reasonably incurred by such person in connection with such action, suit or proceeding if such person acted in good faith and in a manner such person
      reasonably believed to be in or not opposed to the best interests of the corporation and, with respect to any criminal action or proceeding, had no reasonable cause to believe his or her conduct was unlawful. A corporation may similarly indemnify
      such person for expenses actually and reasonably incurred by such person in connection with the defense or settlement of any action or suit by or in the right of the corporation, provided that such person acted in good faith and in a manner he or she
      reasonably believed to be in or not opposed to the best interests of the corporation, and, in the case of claims, issues and matters as to which such person shall have been adjudged liable to the corporation, provided that a court shall have
      determined, upon application, that, despite the adjudication of liability but in view of all of the circumstances of the case, such person is fairly and reasonably entitled to indemnity for such expenses which such court shall deem proper.
In accordance with Section 102(b)(7) of the DGCL, the Registrant's Second Amended and Restated Certificate of Incorporation, as amended (the "
Charter
") provides that a director will not be
      personally liable to the Registrant or its stockholders for monetary damages for breach of fiduciary duty as a director, except to the extent such exemption from liability or limitation thereof is not permitted under the DGCL. No such provision shall
      eliminate or limit the liability of a director for any act or omission occurring prior to the date when such provision became effective. Accordingly, these provisions will have no effect on the availability of equitable remedies such as an injunction
      or rescission based on a director's breach of his or her duty of care.
The Charter provides that the Registrant will indemnify its present and former directors and officers to the maximum extent permitted by the DGCL and that such indemnification will not be exclusive
      of any other rights to which those seeking indemnification may have or hereafter acquire under any statute, provision of the Charter, the Registrant's bylaws, agreement, vote of stockholders or disinterested directors or otherwise.
The Registrant has entered into, and expects to continue to enter into, customary indemnification arrangements with each of its current directors and executive officers. These arrangements require
      the Registrant to indemnify these individuals to the fullest extent permitted under Delaware law against liabilities that may arise by reason of their service to the Registrant, and to advance expenses incurred as a result of any proceeding against
      them as to which they could be indemnified. The Registrant also intends to enter into indemnification arrangements with future directors and executive officers.
See also the undertakings set out in response to Item 9 hereof.
Item 7.
Exemption from Registration Claimed.
Not applicable.
Item 8.
Exhibits.
The Registrant hereby files the exhibits set forth below:
Exhibit Number
Description of Exhibit
4.1
Second Amended and Restated Certificate of Incorporation of the ADMA Biologics, Inc. (incorporated herein by reference to Exhibit 3.1 to the Registrant's Current Report on Form 8-K, filed
              with the Commission on August 23, 2019).
4.2
Certificate of Amendment of the Second Amended and Restated Certificate of Incorporation of ADMA Biologics, Inc., dated as of May 27, 2021 (incorporated by reference to Exhibit 3.1 to the
              Registrant's Current Report on Form 8-K filed with the Commission on May 28, 2021).
4.3
Amended and Restated Bylaws (incorporated herein by reference to Exhibit 3.1 to the Registrant's Current Report on Form 8-K, filed with the Commission on October 7, 2016).
5.1
Opinion of Morgan, Lewis and Bockius LLP, counsel for the Registrant, regarding the legal validity of the shares of Common Stock being registered on this Registration Statement (filed
              herewith).
10.1
ADMA Biologics, Inc. 2022 Equity Compensation Plan (incorporated herein by reference to Exhibit 10.1 to the Registrant's Current Report on Form 8-K filed with the Commission on June 21,
              2022).
23.1
Consent of Morgan, Lewis and Bockius LLP (contained in Exhibit 5.1).
23.2
Consent of CohnReznick LLP, the Registrant's Independent Registered Public Accounting Firm
(filed herewith).
24.1
Power of Attorney (included on signature page).
107
Filing Fee Exhibit
Item 9.
Undertakings.
(a)
The undersigned Registrant hereby undertakes:
1.
To file, during any period in which offers or sales are being made, a post-effective amendment to this registration statement:
i.
To include any prospectus required by Section 10(a)(3) of the Securities Act;
ii.
To reflect in the prospectus any facts or events arising after the effective date of the registration statement (or the most recent post-effective amendment thereof) which, individually or in the
                    aggregate, represent a fundamental change in the information set forth in the registration statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities
                    offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in
                    the aggregate, the changes in volume and price represent no more than a 20% change in the maximum aggregate offering price set forth in the "Calculation of Registration Fee" table in the effective registration statement.
iii.
To include any material information with respect to the plan of distribution not previously disclosed in the registration statement or any material change to such information in the registration
                    statement;
Provided, however,
that paragraphs (a)(i) and (a)(ii) do not apply if the information required to be included in a post-effective amendment by those
        paragraphs is contained in reports filed with or furnished to the Commission by the Registrant pursuant to Section 13 or Section 15(d) of the Exchange Act that are incorporated by reference in the registration statement.
2.
That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered herein,
                  and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.
3.
To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.
4.
That, for the purpose of determining liability of the Registrant under the Securities Act to any purchaser in the initial distribution of the securities, the undersigned Registrant undertakes that in a
                    primary offering of securities of the undersigned Registrant pursuant to this registration statement, regardless of the underwriting method used to sell the securities to the purchaser, if the securities are offered or sold to such
                    purchaser by means of any of the following communications, the undersigned Registrant will be a seller to the purchaser and will be considered to offer or sell such securities to such purchaser:
i.
Any preliminary prospectus or prospectus of the undersigned Registrant relating to the offering required to be filed pursuant to Rule 424,
ii.
Any free writing prospectus relating to the offering prepared by or on behalf of the undersigned Registrant or used or referred to by the undersigned Registrant,
iii.
The portion of any other free writing prospectus relating to the offering containing material information about the undersigned Registrant or its securities provided by or on behalf of the undersigned
                    Registrant, and
iv.
Any other communication that is an offer in the offering made by the undersigned Registrant to the purchaser.
5.
That, for purposes of determining any liability under the Securities Act, each filing of the Registrant's annual report pursuant to Section 13(a) or Section 15(d) of the Exchange Act (and, where
                    applicable, each filing of an employee benefit plan's annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in the Registration Statement shall be deemed to be a new registration statement
                    relating to the securities offered herein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.
(b)
Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the Registrant pursuant to the foregoing provisions, or
                otherwise, the Registrant has been advised that in the opinion of the Commission such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for
                indemnification against such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is
                asserted by such director, officer or controlling person in connection with the securities being registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court
                of appropriate jurisdiction the question whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8
      and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Ramsey, State of New Jersey, on this 22
nd
day of July, 2022.
ADMA Biologics, Inc.
(Registrant)
By:
/s/ Brian Lenz
Name: Brian Lenz
Title: Executive Vice President and Chief Financial Officer
POWER OF ATTORNEY
KNOW BY ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Adam S. Grossman and Brian Lenz, and each of them, the undersigned's true and lawful
      attorneys-in-fact and agents, with full power of substitution and revocation, for and in the undersigned's name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective amendments) to this Registration
      Statement on Form S-8 (this "
Registration Statement
") and any registration statement filed pursuant to Rule 462(b) under the Securities Act of 1933, as amended (the "
Securities Act
"), and to file the same, with all exhibits thereto, and
      other documents in connection therewith, with the Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite and necessary to be done, as fully to
      all intents and purposes as the undersigned might or could do in person, hereby ratify and confirming all that said attorneys-in-fact and agents or any of them, or their or his substitutes, may lawfully do or cause to be done by virtue thereof.
Pursuant to the requirements of the Securities Act, this Registration Statement has been signed below by the following persons on behalf of the Registrant and in the capacities indicated on the date
      listed below.
Signature
Capacity
Date
/s/ Adam S. Grossman
President and Chief Executive Officer, Director
July 22, 2022
Adam S. Grossman
(Principal Executive Officer)
/s/ Brian Lenz
Executive Vice President and Chief Financial Officer
July 22, 2022
Brian Lenz
(Principal Financial Officer and Principal Accounting Officer)
/s/ Steven A. Elms
Chairman of the Board of Directors
July 22, 2022
Steven A. Elms
/s/ Dr. Jerrold B. Grossman
Vice Chairman of the Board of Directors
July 22, 2022
Dr. Jerrold B. Grossman
/s/ Martha J. Demski
Director
July 22, 2022
Martha J. Demski
/s/ Bryant E. Fong
Director
July 22, 2022
Bryant E. Fong
/s/ Lawrence P. Guiheen
Director
July 22, 2022
Lawrence P. Guiheen
/s/ Young T. Kwon
Director
July 22, 2022
Young T. Kwon