<html>
  <head>
    <title></title>
    <!-- Licensed to: Broadridge
         Document created using Broadridge PROfile 22.10.2.5096
         Copyright 1995 - 2022 Broadridge -->
  </head>
<body bgcolor="#ffffff" style="font-family: 'Times New Roman'; font-size: 10pt; text-align: left; color: #000000;">
  <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">As filed with the Securities and Exchange Commission on December 20, 2022</div>
  <div><br>
  </div>
  <div style="text-align: right; color: rgb(0, 0, 0); font-weight: bold;">Registration No. 333-</div>
  <div>
    <div><font style="color: rgb(0, 0, 0);"> </font>
      <hr align="center" style="border: none; border-bottom: 1px solid black; border-top: 4px solid black; height: 10px; color: #ffffff; background-color: #ffffff; text-align: center; margin-left: auto; margin-right: auto;"></div>
  </div>
  <div style="font-size: 14pt;">
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">UNITED STATES</div>
  </div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-size: 14pt; font-weight: bold;">SECURITIES AND EXCHANGE COMMISSION</div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-size: 12pt; font-weight: bold;">Washington, D.C. 20549</div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;"> <br>
  </div>
  <div><font style="color: rgb(0, 0, 0);"> </font>
    <hr noshade="noshade" align="center" style="height: 2px; color: #000000; background-color: #000000; text-align: center; margin-left: auto; margin-right: auto; border: none;"></div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-size: 18pt; font-weight: bold;">FORM S-8</div>
  <div>&#160;</div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">REGISTRATION STATEMENT</div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-style: italic; font-weight: bold;">UNDER</div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-style: italic; font-weight: bold;">THE SECURITIES ACT OF 1933</div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-style: italic; font-weight: bold;"> <br>
  </div>
  <div><font style="color: rgb(0, 0, 0);"> </font>
    <hr noshade="noshade" align="center" style="height: 2px; color: #000000; background-color: #000000; text-align: center; margin-left: auto; margin-right: auto; border: none;"></div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-size: 24pt; font-weight: bold;">Rocket Pharmaceuticals, Inc.</div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">(Exact name of registrant as specified in its charter)</div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;"> <br>
  </div>
  <div><font style="color: rgb(0, 0, 0);"> </font>
    <hr noshade="noshade" align="center" style="height: 2px; color: #000000; background-color: #000000; text-align: center; margin-left: auto; margin-right: auto; border: none;"></div>
  <div> <br>
  </div>
  <table cellspacing="0" cellpadding="0" border="0" id="z590d3ad1ae8849acbaffa185c54e9fd6" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

      <tr>
        <td style="width: 49%; vertical-align: top;">
          <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Delaware</div>
        </td>
        <td style="width: 2%; vertical-align: bottom;">&#160;</td>
        <td style="width: 49%; vertical-align: top;">
          <div style="text-align: center; font-weight: bold;">04-3475813</div>
        </td>
      </tr>
      <tr>
        <td style="width: 49%; vertical-align: top;">
          <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">(State or other jurisdiction of incorporation or organization)</div>
        </td>
        <td style="width: 2%; vertical-align: bottom;">&#160;</td>
        <td style="width: 49%; vertical-align: top;">
          <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">(I.R.S. Employer Identification No.)</div>
        </td>
      </tr>

  </table>
  <div>&#160;</div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Rocket Pharmaceuticals, Inc.</div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">9 Cedarbrook Drive</div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Cranbury, NJ 08512</div>
  <div style="text-align: center; color: rgb(0, 0, 0);">(Address of principal executive offices, including zip code)</div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">(646) 440-9100</div>
  <div style="text-align: center; color: rgb(0, 0, 0);">(Registrant&#8217;s telephone number, including area code)</div>
  <div>&#160;</div>
  <div style="text-align: center; color: #000000;"><font style="font-weight: bold;">Second Amended and Restated Rocket Pharmaceuticals, Inc.</font>&#160;<font style="font-weight: bold;">2014 Stock Option and Incentive Plan</font></div>
  <div style="text-align: center; color: rgb(0, 0, 0);">(Full title of the plans)</div>
  <div style="text-align: center; color: rgb(0, 0, 0);"> <br>
  </div>
  <div><font style="color: rgb(0, 0, 0);"> </font>
    <hr noshade="noshade" align="center" style="height: 2px; color: #000000; background-color: #000000; text-align: center; margin-left: auto; margin-right: auto; border: none;"></div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Gaurav Shah, MD</div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">President and Chief Executive Officer</div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Rocket Pharmaceuticals, Inc.</div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">9 Cedarbrook Drive</div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Cranbury, NJ 08512</div>
  <div style="text-align: center; color: rgb(0, 0, 0);">(Name and address, including zip code, of agent for service)</div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">(646) 440-9100</div>
  <div style="text-align: center; color: rgb(0, 0, 0);">(Telephone number, including area code, of agent for service)</div>
  <div style="text-align: center; color: rgb(0, 0, 0);"> <br>
  </div>
  <div><font style="color: rgb(0, 0, 0);"> </font>
    <hr noshade="noshade" align="center" style="height: 2px; color: #000000; background-color: #000000; text-align: center; margin-left: auto; margin-right: auto; border: none;"></div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-style: italic; font-weight: bold;">Please send copies of all communications to:</div>
  <div><font style="color: rgb(0, 0, 0);"> </font><br>
  </div>
  <table cellspacing="0" cellpadding="0" border="0" id="z57e7ea6d95784e039e8ba9f6737e2790" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

      <tr>
        <td style="width: 49%; vertical-align: top;">
          <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Sarah Ashfaq, Esq.</div>
          <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">William D. Collins, Esq.</div>
          <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Goodwin Procter LLP</div>
          <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">The New York Times Building</div>
          <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">620 Eighth Avenue</div>
          <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">New York, NY 10018</div>
          <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">(212) 813-8800</div>
        </td>
        <td style="width: 1.7%; vertical-align: bottom;">&#160;</td>
        <td style="width: 49%; vertical-align: top;">
          <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Martin Wilson, Esq.</div>
          <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">General Counsel &amp; Chief Compliance Officers, SVP</div>
          <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Rocket Pharmaceuticals, Inc.</div>
          <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">9 Cedarbrook Drive</div>
          <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Cranbury, NJ 08512</div>
          <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">(646) 440-9100</div>
          <div>&#160;</div>
        </td>
      </tr>

  </table>
  <div><font style="color: rgb(0, 0, 0);"> </font><br>
  </div>
  <div>
    <div style="text-align: center;"><font style="color: rgb(0, 0, 0);"> </font>
      <hr align="center" style="border: none; border-bottom: 4px solid black; border-top: 1px solid black; height: 10px; color: #ffffff; background-color: #ffffff; margin-left: auto; margin-right: auto;"></div>
  </div>
  <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
    <div class="BRPFPageBreak" style="page-break-after: always;">
      <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
  </div>
  <div style="text-align: justify;">Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company.&#160; See the definitions of <font style="color: rgb(0, 0, 0);">&#8220;</font>large accelerated filer,<font style="color: rgb(0, 0, 0);">&#8221;</font>&#160;<font style="color: rgb(0, 0, 0);">&#8220;</font>accelerated filer,<font style="color: rgb(0, 0, 0);">&#8221;</font>&#160;<font style="color: rgb(0, 0, 0);">&#8220;</font>smaller



    reporting company,<font style="color: rgb(0, 0, 0);">&#8221;</font> and <font style="color: rgb(0, 0, 0);">&#8220;</font>emerging growth company<font style="color: rgb(0, 0, 0);">&#8221;</font> in Rule 12b-2 of the Exchange Act.</div>
  <div><font style="color: rgb(0, 0, 0);"> </font><br>
  </div>
  <table cellspacing="0" cellpadding="0" border="0" id="z4bf178a71bbf43cdbbad4608bd1207cb" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

      <tr>
        <td style="width: 21%; vertical-align: bottom;">
          <div>Large accelerated filer</div>
        </td>
        <td style="width: 54%; vertical-align: bottom;">&#9746;</td>
        <td style="width: 22%; vertical-align: bottom;">
          <div>Accelerated filer</div>
        </td>
        <td style="width: 3.32%; vertical-align: bottom;">&#9744;</td>
      </tr>
      <tr>
        <td style="width: 21%; vertical-align: bottom;">&#160;</td>
        <td style="width: 54%; vertical-align: bottom;">&#160;</td>
        <td style="width: 22%; vertical-align: bottom;">&#160;</td>
        <td style="width: 3.32%; vertical-align: bottom;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 21%; vertical-align: bottom;">
          <div>Non-accelerated filer</div>
        </td>
        <td style="width: 54%; vertical-align: bottom;">&#9744;</td>
        <td style="width: 22%; vertical-align: bottom;">
          <div>Smaller reporting company</div>
        </td>
        <td style="width: 3.32%; vertical-align: bottom;">&#9744;</td>
      </tr>
      <tr>
        <td style="width: 21%; vertical-align: bottom;">&#160;</td>
        <td style="width: 54%; vertical-align: bottom;">&#160;</td>
        <td style="width: 22%; vertical-align: bottom;">&#160;</td>
        <td style="width: 3.32%; vertical-align: bottom;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 21%; vertical-align: bottom;">
          <div>Emerging growth company</div>
        </td>
        <td style="width: 54%; vertical-align: bottom;">&#9744;</td>
        <td style="width: 22%; vertical-align: bottom;">&#160;</td>
        <td style="width: 3.32%; vertical-align: bottom;">&#160;</td>
      </tr>

  </table>
  <div>&#160;</div>
  <div style="text-align: justify;">If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to
    Section 7(a)(2)(B) of the Securities Act.&#160; &#9744;</div>
  <div>&#160;</div>
  <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">EXPLANATORY NOTE</div>
  <div>&#160;</div>
  <div style="text-align: justify; color: rgb(0, 0, 0);">This Registration Statement on Form S-8 registers 5,020,091 additional shares of Common Stock under the Second Amended and Restated Rocket Pharmaceuticals, Inc. 2014 Stock Option and Incentive Plan
    (the &#8220;<u>Plan</u>&#8221;). The number of shares of Common Stock reserved and available for issuance under the Plan is subject to an automatic annual increase on each January 1, beginning in 2020, by an amount equal to the lesser of: (i) four percent (4%) of
    the number of shares of Common Stock issued and outstanding on the immediately preceding December 31 or (ii) such number of shares of Common Stock as determined by the compensation committee of the Company&#8217;s board of directors. Accordingly, on January
    1, 2021, and January 1, 2022, the number of shares of Common Stock reserved and available for issuance under the Plan increased by 2,439,855 and 2,580,236, respectively. The additional shares are of the same class as other securities relating to the
    Plan for which the Registrant&#8217;s registration statements filed on Form S-8 filed with the Securities and Exchange Commission on March 6, 2020 (<a href="https://www.sec.gov/Archives/edgar/data/1281895/000114036120005062/forms8.htm">File No. 333-236946</a>),



    March 7, 2018 (<a href="https://www.sec.gov/Archives/edgar/data/1281895/000119312518073524/d527889ds8.htm">Registration No. 333-223488</a>), March 23, 2017 (<a href="https://www.sec.gov/Archives/edgar/data/1281895/000119312517092821/d361865ds8.htm">Registration



      No. 333-216892</a>), June 29, 2016 (<a href="https://www.sec.gov/Archives/edgar/data/1281895/000119312516636655/d218658ds8.htm">Registration No. 333-212308</a>) and May 28, 2015 (<a href="https://www.sec.gov/Archives/edgar/data/1281895/000119312515204038/d933094ds8.htm">Registration No. 333-204501</a>), are effective. The information contained in the Registrant&#8217;s registration statements on Form S-8 (Registration Nos. 333-236946,
    333- 223488, 333-216892, 333-212308 and 333-204501) are hereby incorporated by reference pursuant to General Instruction E.</div>
  <div><br>
  </div>
  <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
    <div class="BRPFPageBreak" style="page-break-after: always;">
      <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
  </div>
  <div>
    <div style="font-weight: bold;">Part II</div>
    <div>&#160;</div>
  </div>
  <div>
    <div style="font-weight: bold;">
      <table cellspacing="0" cellpadding="0" id="zba953d3d9a874a569380c38d646f527a" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

          <tr>
            <td style="width: 100%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
              <div>
                <div style="font-weight: bold;">INFORMATION REQUIRED IN THE REGISTRATION STATEMENT </div>
              </div>
            </td>
          </tr>

      </table>
    </div>
  </div>
  <table cellspacing="0" cellpadding="0" id="z6256d391a6b84004b3a831cbb6a5557a" class="DSPFListTable" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

      <tr>
        <td style="width: 18pt;"><br>
        </td>
        <td style="width: 54pt; vertical-align: top; font-weight: bold;">Item 8.</td>
        <td style="width: auto; vertical-align: top;">
          <div style="font-weight: bold;">Exhibits.</div>
        </td>
      </tr>

  </table>
  <div>&#160;</div>
  <table cellspacing="0" cellpadding="0" border="0" id="z4e8e3cbe056544d79cfbe1e7e36cc392" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

      <tr>
        <td style="width: 7.32%; vertical-align: bottom;">
          <div style="font-weight: bold;">Exhibit</div>
          <div style="font-weight: bold;">No.</div>
        </td>
        <td style="width: 92.56%; vertical-align: bottom;">
          <div style="text-align: center; font-weight: bold;">Description</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div><a href="brhc10045666_ex5-1.htm">5.1*</a></div>
        </td>
        <td style="width: 92.56%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div>Opinion of Goodwin Procter LLP.</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top;" rowspan="1">&#160;</td>
        <td style="width: 92.56%; vertical-align: top;" rowspan="1">&#160;</td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div><a href="brhc10045666_ex5-1.htm">23.1*</a></div>
        </td>
        <td style="width: 92.56%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div>Consent of Goodwin Procter LLP (included in Exhibit 5.1).</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top;" rowspan="1">&#160;</td>
        <td style="width: 92.56%; vertical-align: top;" rowspan="1">&#160;</td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div><a href="brhc10045666_ex23-2.htm">23.2*</a></div>
        </td>
        <td style="width: 92.56%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div>Consent of EisnerAmper LLP, independent registered public accounting firm.</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top;">&#160;</td>
        <td style="width: 92.56%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div><a href="#POWEROFATTORNEY">24.1*</a></div>
        </td>
        <td style="width: 92.56%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div>Power of Attorney (included on signature page).</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top;" rowspan="1">&#160;</td>
        <td style="width: 92.56%; vertical-align: top;" rowspan="1">&#160;</td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div><a href="https://www.sec.gov/Archives/edgar/data/1281895/000119312518143310/d535515ddef14a.htm">99.1</a></div>
        </td>
        <td style="width: 92.56%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div style="text-align: justify;">Second Amended and Restated 2014 Stock Option and Incentive Plan (Incorporated by reference to Appendix A to the Registrant&#8217;s Definitive Proxy Statement on Schedule 14A (File No. 001-36829) filed with the
            Securities and Exchange Commission on April 20, 2018).</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top;" rowspan="1">&#160;</td>
        <td style="width: 92.56%; vertical-align: top;" rowspan="1">&#160;</td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div><a href="https://www.sec.gov/Archives/edgar/data/1281895/000114036118036347/ex10_2.htm">99.2</a></div>
        </td>
        <td style="width: 92.56%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div style="text-align: justify;">Form of Incentive Stock Option Agreement (Employees) (Incorporated by reference to Exhibit 10.3# to the Registrant&#8217;s Annual Report on Form 10-K (File No. 001-36829) filed with the Securities and Exchange
            Commission on March 8, 2019).</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top;" rowspan="1">&#160;</td>
        <td style="width: 92.56%; vertical-align: top;" rowspan="1">&#160;</td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div><a href="https://www.sec.gov/Archives/edgar/data/1281895/000114036118036347/ex10_3.htm">99.3</a></div>
        </td>
        <td style="width: 92.56%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div style="text-align: justify;">Form of Non-Qualified Stock Option Agreement (Employees) (Incorporated by reference to Exhibit 10.4# to the Registrant&#8217;s Annual Report on Form 10-K (File No. 001-36829) filed with the Securities and Exchange
            Commission on March 8, 2019).</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top;" rowspan="1">&#160;</td>
        <td style="width: 92.56%; vertical-align: top;" rowspan="1">&#160;</td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div><a href="https://www.sec.gov/Archives/edgar/data/1281895/000114036118036347/ex10_4.htm">99.4</a></div>
        </td>
        <td style="width: 92.56%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div style="text-align: justify;">Form of Non-Qualified Stock Option Agreement (Non-Employee Directors) (Incorporated by reference to Exhibit 10.5# to the Registrant&#8217;s Annual Report on Form 10-K (File No. 001-36829) filed with the Securities and
            Exchange Commission on March 8, 2019).</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top;" rowspan="1">&#160;</td>
        <td style="width: 92.56%; vertical-align: top;" rowspan="1">&#160;</td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div><a href="https://www.sec.gov/Archives/edgar/data/1281895/000114036118036347/ex10_5.htm">99.5</a></div>
        </td>
        <td style="width: 92.56%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div style="text-align: justify;">Form of Non-Qualified Stock Option Agreement (Consultants) (Incorporated by reference to Exhibit 10.6# to the Registrant&#8217;s Annual Report on Form 10-K (File No. 001-36829) filed with the Securities and Exchange
            Commission on March 8, 2019).</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top;" rowspan="1">&#160;</td>
        <td style="width: 92.56%; vertical-align: top;" rowspan="1">&#160;</td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div><a href="https://www.sec.gov/Archives/edgar/data/1281895/000114036120005056/ex10_61.htm">99.6</a></div>
        </td>
        <td style="width: 92.56%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div style="text-align: justify;">Form of Restricted Stock Unit Award Agreement (Incorporated by reference to Exhibit 10.6.1# to the Registrant&#8217;s Annual Report on Form 10-K (File No. 001-36829) filed with the Securities and Exchange Commission on
            March 6, 2020).</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top;">&#160;</td>
        <td style="width: 92.56%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div><a href="https://www.sec.gov/Archives/edgar/data/1281895/000000000014057980/filename1.pdf">99.7</a></div>
        </td>
        <td style="width: 92.56%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div style="text-align: justify;">Amended and Restated 2014 Employee Stock Purchase Plan (Incorporated by reference to Exhibit 10.10 to the Registrant&#8217;s Annual Report on Form 10-K (File No. 001-36829) filed with the Securities and Exchange
            Commission on March 7, 2018).</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top;">&#160;</td>
        <td style="width: 92.56%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 7.32%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div><a href="brhc10045666_ex107.htm">107*</a></div>
        </td>
        <td style="width: 92.56%; vertical-align: top; background-color: rgb(204, 238, 255);">
          <div>Filing Fee Table.</div>
        </td>
      </tr>

  </table>
  <div><br>
  </div>
  <div>
    <hr noshade="noshade" align="left" style="height: 2px; width: 20%; color: #000000; background-color: #000000; margin-left: 0px; margin-right: auto; border: none;"></div>
  <table cellspacing="0" cellpadding="0" id="z45e9c28110fc4c18a1df1ce784f25109" class="DSPFListTable" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

      <tr>
        <td style="width: 9pt;"><br>
        </td>
        <td style="width: 45pt; vertical-align: top;">*</td>
        <td style="width: auto; vertical-align: top;">
          <div>Filed herewith.</div>
        </td>
      </tr>

  </table>
  <div><br>
  </div>
  <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
    <div class="BRPFPageBreak" style="page-break-after: always;">
      <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
  </div>
  <div style="text-align: center; font-weight: bold;">SIGNATURES</div>
  <div>&#160;</div>
  <div style="text-align: justify; text-indent: 18pt;">Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8
    and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Cranbury, State of New Jersey, on December 20, 2022.</div>
  <div>&#160;</div>
  <table cellspacing="0" cellpadding="0" border="0" id="z35d49f008be349fd9a338a4a7719f7ed" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

      <tr>
        <td style="width: 50%; vertical-align: top;">&#160;</td>
        <td style="width: 50%; vertical-align: top;">
          <div style="font-weight: bold;">ROCKET PHARMACEUTICALS, INC.</div>
        </td>
      </tr>
      <tr>
        <td style="width: 50%; vertical-align: top;">&#160;</td>
        <td style="width: 50%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 50%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
        <td style="width: 50%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div>/s/ Gaurav Shah, MD</div>
        </td>
      </tr>
      <tr>
        <td style="width: 50%; vertical-align: top;">&#160;</td>
        <td style="width: 50%; vertical-align: top;">
          <div>Gaurav Shah, MD</div>
        </td>
      </tr>
      <tr>
        <td style="width: 50%; vertical-align: top;">&#160;</td>
        <td style="width: 50%; vertical-align: top;">
          <div>Chief Executive Officer</div>
        </td>
      </tr>

  </table>
  <div><br>
  </div>
  <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
    <div class="BRPFPageBreak" style="page-break-after: always;">
      <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
  </div>
  <div style="text-align: center; font-weight: bold;"><a name="POWEROFATTORNEY"><!--Anchor--></a>POWER OF ATTORNEY AND SIGNATURES</div>
  <div>&#160;</div>
  <div style="text-align: justify; text-indent: 18pt;"><font style="font-weight: bold;">KNOW ALL PERSONS BY THESE PRESENTS</font>, that each person whose signature appears below hereby constitutes and appoints Gaurav Shah, MD and Martin Wilson, JD, and
    each of them, as his or her true and lawful attorney-in-fact and agent with the full power of substitution, for him or her, in any and all capacities, to sign any and all amendments to this Registration Statement (including post-effective amendments to
    this Registration Statement on Form S-8), and to file the same, with all exhibits thereto and other documents in connection therewith, with the Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to
    do and perform each and every act and thing requisite and necessary to be done in connection therewith, as fully for all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and
    agents, or his or her substitutes, may lawfully do or cause to be done by virtue hereof.</div>
  <div>&#160;</div>
  <div style="text-align: justify; text-indent: 18pt;">Pursuant to the requirements of the Securities Act, this Registration Statement has been signed by the following persons on behalf of the Registrant in the capacities and on the dates indicated:</div>
  <div>&#160;</div>
  <table cellspacing="0" cellpadding="0" border="0" id="z4288a74b93a1439c8c952fa5c5b69102" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

      <tr>
        <td style="width: 34%; vertical-align: top;">
          <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;"><u>Name</u></div>
        </td>
        <td style="width: 2%; vertical-align: top;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: top;">
          <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;"><u>Title</u></div>
        </td>
        <td style="width: 2%; vertical-align: top;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: top;">
          <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;"><u>Date</u></div>
        </td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle;" rowspan="1">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" rowspan="1" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle;" rowspan="1">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" rowspan="1" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle;" rowspan="1">&#160;</td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: center;">/s/ Gaurav Shah</div>
        </td>
        <td style="width: 2%; vertical-align: middle; padding-bottom: 2px;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle; padding-bottom: 2px;">
          <div style="text-align: center;">Chief Executive Officer and Director</div>
        </td>
        <td style="width: 2%; vertical-align: middle; padding-bottom: 2px;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle; padding-bottom: 2px;">
          <div style="text-align: center;">December 20, 2022</div>
        </td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle;">
          <div style="text-align: center;">Gaurav Shah, M.D.</div>
        </td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle;">
          <div style="text-align: center; font-style: italic;">(Principal Executive Officer)</div>
        </td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: center;">/s/ John C. Militello</div>
        </td>
        <td style="width: 2%; vertical-align: middle; padding-bottom: 2px;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle; padding-bottom: 2px;">
          <div style="text-align: center;">VP of Finance, Senior Controller and Treasurer</div>
        </td>
        <td style="width: 2%; vertical-align: middle; padding-bottom: 2px;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle; padding-bottom: 2px;">
          <div style="text-align: center;">December 20, 2022</div>
        </td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle;">
          <div style="text-align: center;">John C. Militello</div>
        </td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle;">
          <div style="text-align: center; font-style: italic;">(Interim Principal Financial Officer and Principal Accounting Officer)</div>
        </td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: center;">/s/ Elisabeth Bj&#246;rk</div>
        </td>
        <td style="width: 2%; vertical-align: middle; padding-bottom: 2px;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle; padding-bottom: 2px;">
          <div style="text-align: center;">Director</div>
        </td>
        <td style="width: 2%; vertical-align: middle; padding-bottom: 2px;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle; padding-bottom: 2px;">
          <div style="text-align: center;">December 20, 2022</div>
        </td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle;">
          <div style="text-align: center;">Elisabeth Bj&#246;rk, M.D., Ph.D.</div>
        </td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: center;">/s/ Roderick Wong</div>
        </td>
        <td style="width: 2%; vertical-align: middle; padding-bottom: 2px;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle; padding-bottom: 2px;">
          <div style="text-align: center;">Director</div>
        </td>
        <td style="width: 2%; vertical-align: middle; padding-bottom: 2px;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle; padding-bottom: 2px;">
          <div style="text-align: center;">December 20, 2022</div>
        </td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle;">
          <div style="text-align: center;">Roderick Wong, M.D.</div>
        </td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: center;">/s/ Naveen Yalamanchi</div>
        </td>
        <td style="width: 2%; vertical-align: middle; padding-bottom: 2px;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle; padding-bottom: 2px;">
          <div style="text-align: center;">Director</div>
        </td>
        <td style="width: 2%; vertical-align: middle; padding-bottom: 2px;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle; padding-bottom: 2px;">
          <div style="text-align: center;">December 20, 2022</div>
        </td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle;">
          <div style="text-align: center;">Naveen Yalamanchi, M.D.</div>
        </td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: center;">/s/ Carsten Boess</div>
        </td>
        <td style="width: 2%; vertical-align: middle; padding-bottom: 2px;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle; padding-bottom: 2px;">
          <div style="text-align: center;">Director</div>
        </td>
        <td style="width: 2%; vertical-align: middle; padding-bottom: 2px;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle; padding-bottom: 2px;">
          <div style="text-align: center;">December 20, 2022</div>
        </td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle;">
          <div style="text-align: center;">Carsten Boess</div>
        </td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: center;">/s/ David P. Southwell</div>
        </td>
        <td style="width: 2%; vertical-align: middle; padding-bottom: 2px;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle; padding-bottom: 2px;">
          <div style="text-align: center;">Director</div>
        </td>
        <td style="width: 2%; vertical-align: middle; padding-bottom: 2px;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle; padding-bottom: 2px;">
          <div style="text-align: center;">December 20, 2022</div>
        </td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle;">
          <div style="text-align: center;">David P. Southwell</div>
        </td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: center;">/s/ Pedro Granadillo</div>
        </td>
        <td style="width: 2%; vertical-align: middle; padding-bottom: 2px;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle; padding-bottom: 2px;">
          <div style="text-align: center;">Director</div>
        </td>
        <td style="width: 2%; vertical-align: middle; padding-bottom: 2px;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle; padding-bottom: 2px;">
          <div style="text-align: center;">December 20, 2022</div>
        </td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle;">
          <div style="text-align: center;">Pedro Granadillo</div>
        </td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: center;">/s/ Gotham Makker</div>
        </td>
        <td style="width: 2%; vertical-align: middle; padding-bottom: 2px;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle; padding-bottom: 2px;">
          <div style="text-align: center;">Director</div>
        </td>
        <td style="width: 2%; vertical-align: middle; padding-bottom: 2px;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle; padding-bottom: 2px;">
          <div style="text-align: center;">December 20, 2022</div>
        </td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle;">
          <div style="text-align: center;">Gotham Makker, M.D.</div>
        </td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: center;">/s/ Fady Malik</div>
        </td>
        <td style="width: 2%; vertical-align: middle; padding-bottom: 2px;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle; padding-bottom: 2px;">
          <div style="text-align: center;">Director</div>
        </td>
        <td style="width: 2%; vertical-align: middle; padding-bottom: 2px;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle; padding-bottom: 2px;">
          <div style="text-align: center;">December 20, 2022</div>
        </td>
      </tr>
      <tr>
        <td style="width: 34%; vertical-align: middle;">
          <div style="text-align: center;">Fady Malik, M.D., Ph.D.</div>
        </td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 39%; vertical-align: middle;">&#160;</td>
        <td style="width: 2%; vertical-align: middle;" colspan="1">&#160;</td>
        <td style="width: 23%; vertical-align: middle;">&#160;</td>
      </tr>

  </table>
  <div><br>
  </div>
  <div>&#160;</div>
  <div>
    <hr noshade="noshade" align="center" style="height: 2px; color: #000000; background-color: #000000; text-align: center; margin-left: auto; margin-right: auto; border: none;"></div>
</body>
</html>
[{"type": "S-8", "sequence": "1", "filename": "brhc10045666_s8.htm", "description": "S-8", "secsgml_size_bytes": 47439}]
{"company-data": {"conformed-name": "ROCKET PHARMACEUTICALS, INC.", "cik": "0001281895", "assigned-sic": "2834", "irs-number": "000000000", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-268908", "film-number": "221474816"}, "business-address": {"street1": "350 FIFTH AVENUE", "street2": "SUITE 7530", "city": "NEW YORK", "state": "NY", "zip": "10118", "phone": "646-440-9100"}, "mail-address": {"street1": "350 FIFTH AVENUE", "street2": "SUITE 7530", "city": "NEW YORK", "state": "NY", "zip": "10118"}, "former-company": {"former-conformed-name": "INOTEK PHARMACEUTICALS CORP", "date-changed": "20040226"}}
As filed with the Securities and Exchange Commission on December 20, 2022
Registration No. 333-
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-8
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
Rocket Pharmaceuticals, Inc.
(Exact name of registrant as specified in its charter)
Delaware
04-3475813
(State or other jurisdiction of incorporation or organization)
(I.R.S. Employer Identification No.)
Rocket Pharmaceuticals, Inc.
9 Cedarbrook Drive
Cranbury, NJ 08512
(Address of principal executive offices, including zip code)
(646) 440-9100
(Registrant's telephone number, including area code)
Second Amended and Restated Rocket Pharmaceuticals, Inc.
2014 Stock Option and Incentive Plan
(Full title of the plans)
Gaurav Shah, MD
President and Chief Executive Officer
Rocket Pharmaceuticals, Inc.
9 Cedarbrook Drive
Cranbury, NJ 08512
(Name and address, including zip code, of agent for service)
(646) 440-9100
(Telephone number, including area code, of agent for service)
Please send copies of all communications to:
Sarah Ashfaq, Esq.
William D. Collins, Esq.
Goodwin Procter LLP
The New York Times Building
620 Eighth Avenue
New York, NY 10018
(212) 813-8800
Martin Wilson, Esq.
General Counsel & Chief Compliance Officers, SVP
Rocket Pharmaceuticals, Inc.
9 Cedarbrook Drive
Cranbury, NJ 08512
(646) 440-9100
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company.  See the definitions of
"
large accelerated filer,
"
"
accelerated filer,
"
"
smaller

    reporting company,
"
and
"
emerging growth company
"
in Rule 12b-2 of the Exchange Act.
Large accelerated filer
☒
Accelerated filer
☐
Non-accelerated filer
☐
Smaller reporting company
☐
Emerging growth company
☐
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to
    Section 7(a)(2)(B) of the Securities Act.  ☐
EXPLANATORY NOTE
This Registration Statement on Form S-8 registers 5,020,091 additional shares of Common Stock under the Second Amended and Restated Rocket Pharmaceuticals, Inc. 2014 Stock Option and Incentive Plan
    (the "
Plan
"). The number of shares of Common Stock reserved and available for issuance under the Plan is subject to an automatic annual increase on each January 1, beginning in 2020, by an amount equal to the lesser of: (i) four percent (4%) of
    the number of shares of Common Stock issued and outstanding on the immediately preceding December 31 or (ii) such number of shares of Common Stock as determined by the compensation committee of the Company's board of directors. Accordingly, on January
    1, 2021, and January 1, 2022, the number of shares of Common Stock reserved and available for issuance under the Plan increased by 2,439,855 and 2,580,236, respectively. The additional shares are of the same class as other securities relating to the
    Plan for which the Registrant's registration statements filed on Form S-8 filed with the Securities and Exchange Commission on March 6, 2020 (
File No. 333-236946
),

    March 7, 2018 (
Registration No. 333-223488
), March 23, 2017 (
Registration

      No. 333-216892
), June 29, 2016 (
Registration No. 333-212308
) and May 28, 2015 (
Registration No. 333-204501
), are effective. The information contained in the Registrant's registration statements on Form S-8 (Registration Nos. 333-236946,
    333- 223488, 333-216892, 333-212308 and 333-204501) are hereby incorporated by reference pursuant to General Instruction E.
Part II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 8.
Exhibits.
Exhibit
No.
Description
5.1*
Opinion of Goodwin Procter LLP.
23.1*
Consent of Goodwin Procter LLP (included in Exhibit 5.1).
23.2*
Consent of EisnerAmper LLP, independent registered public accounting firm.
24.1*
Power of Attorney (included on signature page).
99.1
Second Amended and Restated 2014 Stock Option and Incentive Plan (Incorporated by reference to Appendix A to the Registrant's Definitive Proxy Statement on Schedule 14A (File No. 001-36829) filed with the
            Securities and Exchange Commission on April 20, 2018).
99.2
Form of Incentive Stock Option Agreement (Employees) (Incorporated by reference to Exhibit 10.3# to the Registrant's Annual Report on Form 10-K (File No. 001-36829) filed with the Securities and Exchange
            Commission on March 8, 2019).
99.3
Form of Non-Qualified Stock Option Agreement (Employees) (Incorporated by reference to Exhibit 10.4# to the Registrant's Annual Report on Form 10-K (File No. 001-36829) filed with the Securities and Exchange
            Commission on March 8, 2019).
99.4
Form of Non-Qualified Stock Option Agreement (Non-Employee Directors) (Incorporated by reference to Exhibit 10.5# to the Registrant's Annual Report on Form 10-K (File No. 001-36829) filed with the Securities and
            Exchange Commission on March 8, 2019).
99.5
Form of Non-Qualified Stock Option Agreement (Consultants) (Incorporated by reference to Exhibit 10.6# to the Registrant's Annual Report on Form 10-K (File No. 001-36829) filed with the Securities and Exchange
            Commission on March 8, 2019).
99.6
Form of Restricted Stock Unit Award Agreement (Incorporated by reference to Exhibit 10.6.1# to the Registrant's Annual Report on Form 10-K (File No. 001-36829) filed with the Securities and Exchange Commission on
            March 6, 2020).
99.7
Amended and Restated 2014 Employee Stock Purchase Plan (Incorporated by reference to Exhibit 10.10 to the Registrant's Annual Report on Form 10-K (File No. 001-36829) filed with the Securities and Exchange
            Commission on March 7, 2018).
107*
Filing Fee Table.
*
Filed herewith.
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8
    and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Cranbury, State of New Jersey, on December 20, 2022.
ROCKET PHARMACEUTICALS, INC.
/s/ Gaurav Shah, MD
Gaurav Shah, MD
Chief Executive Officer
POWER OF ATTORNEY AND SIGNATURES
KNOW ALL PERSONS BY THESE PRESENTS
, that each person whose signature appears below hereby constitutes and appoints Gaurav Shah, MD and Martin Wilson, JD, and
    each of them, as his or her true and lawful attorney-in-fact and agent with the full power of substitution, for him or her, in any and all capacities, to sign any and all amendments to this Registration Statement (including post-effective amendments to
    this Registration Statement on Form S-8), and to file the same, with all exhibits thereto and other documents in connection therewith, with the Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to
    do and perform each and every act and thing requisite and necessary to be done in connection therewith, as fully for all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and
    agents, or his or her substitutes, may lawfully do or cause to be done by virtue hereof.
Pursuant to the requirements of the Securities Act, this Registration Statement has been signed by the following persons on behalf of the Registrant in the capacities and on the dates indicated:
Name
Title
Date
/s/ Gaurav Shah
Chief Executive Officer and Director
December 20, 2022
Gaurav Shah, M.D.
(Principal Executive Officer)
/s/ John C. Militello
VP of Finance, Senior Controller and Treasurer
December 20, 2022
John C. Militello
(Interim Principal Financial Officer and Principal Accounting Officer)
/s/ Elisabeth Björk
Director
December 20, 2022
Elisabeth Björk, M.D., Ph.D.
/s/ Roderick Wong
Director
December 20, 2022
Roderick Wong, M.D.
/s/ Naveen Yalamanchi
Director
December 20, 2022
Naveen Yalamanchi, M.D.
/s/ Carsten Boess
Director
December 20, 2022
Carsten Boess
/s/ David P. Southwell
Director
December 20, 2022
David P. Southwell
/s/ Pedro Granadillo
Director
December 20, 2022
Pedro Granadillo
/s/ Gotham Makker
Director
December 20, 2022
Gotham Makker, M.D.
/s/ Fady Malik
Director
December 20, 2022
Fady Malik, M.D., Ph.D.