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      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001830053</cik>
            <ccc>XXXXXXXX</ccc>
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        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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      <issuerInfo>
        <issuerCik>0001770121</issuerCik>
        <issuerName>Sana Biotechnology, Inc.</issuerName>
        <secFileNumber>001-39941</secFileNumber>
        <issuerAddress>
          <com:street1>188 EAST BLAINE STREET, SUITE 400</com:street1>
          <com:city>SEATTLE</com:city>
          <com:stateOrCountry>WA</com:stateOrCountry>
          <com:zipCode>98102</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>(206) 701-7914</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Hardy Nathan</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Former CFO</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Morgan Stanley Smith Barney LLC  Executive Financial Services</name>
          <address>
            <com:street1>1 New York Plaza</com:street1>
            <com:street2>8th Floor</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10004</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>91607</noOfUnitsSold>
        <aggregateMarketValue>229017.50</aggregateMarketValue>
        <noOfUnitsOutstanding>223268889</noOfUnitsOutstanding>
        <approxSaleDate>11/26/2024</approxSaleDate>
        <securitiesExchangeName>Nasdaq</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Class A</securitiesClassTitle>
        <acquiredDate>07/23/2019</acquiredDate>
        <natureOfAcquisitionTransaction>Founders Stock</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>91607</amountOfSecuritiesAcquired>
        <paymentDate>07/23/2019</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>NATHAN HARDY</name>
          <address>
            <com:street1>188 East Blaine Street</com:street1>
            <com:street2>Suite 400</com:street2>
            <com:city>Seattle</com:city>
            <com:stateOrCountry>WA</com:stateOrCountry>
            <com:zipCode>98102</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>11/25/2024</saleDate>
        <amountOfSecuritiesSold>25933</amountOfSecuritiesSold>
        <grossProceeds>64959.57</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name> NATHAN HARDY</name>
          <address>
            <com:street1>188 East Blaine Street</com:street1>
            <com:street2>Suite 400</com:street2>
            <com:city>Seattle</com:city>
            <com:stateOrCountry>WA</com:stateOrCountry>
            <com:zipCode>98102</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>10/21/2024</saleDate>
        <amountOfSecuritiesSold>45796</amountOfSecuritiesSold>
        <grossProceeds>180807.19</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>11/26/2024</noticeDate>
        <signature> /s/ Nathan Richard Hardy</signature>
      </noticeSignature>
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text: 144
  0001830053
  XXXXXXXX
  LIVE
  0001770121
  Sana Biotechnology, Inc.
  001-39941
  188 EAST BLAINE STREET, SUITE 400
  SEATTLE
  WA
  98102
  (206) 701-7914
  Hardy Nathan
  Former CFO
  Common
  Morgan Stanley Smith Barney LLC  Executive Financial Services
  1 New York Plaza
  8th Floor
  New York
  NY
  10004
  91607
  229017.50
  223268889
  11/26/2024
  Nasdaq
  Class A
  07/23/2019
  Founders Stock
  Issuer
  N
  91607
  07/23/2019
  Cash
  N
  NATHAN HARDY
  188 East Blaine Street
  Suite 400
  Seattle
  WA
  98102
  Common
  11/25/2024
  25933
  64959.57
  NATHAN HARDY
  188 East Blaine Street
  Suite 400
  Seattle
  WA
  98102
  Common
  10/21/2024
  45796
  180807.19
  11/26/2024
  /s/ Nathan Richard Hardy