content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001662008</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0000313616</issuerCik>
        <issuerName>DANAHER CORP /DE/</issuerName>
        <secFileNumber>001-08089</secFileNumber>
        <issuerAddress>
          <com:street1>2200 PENNSYLVANIA AVE. N.W.</com:street1>
          <com:street2>SUITE 800W</com:street2>
          <com:city>WASHINGTON</com:city>
          <com:stateOrCountry>DC</com:stateOrCountry>
          <com:zipCode>20037-1701</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>2028280850</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Ellis Brian W</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem Street</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>5700</noOfUnitsSold>
        <aggregateMarketValue>1277541.57</aggregateMarketValue>
        <noOfUnitsOutstanding>722275141</noOfUnitsOutstanding>
        <approxSaleDate>01/30/2025</approxSaleDate>
        <securitiesExchangeName>NYSE</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>01/30/2025</acquiredDate>
        <natureOfAcquisitionTransaction>Option Granted 02/24/2016</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>5700</amountOfSecuritiesAcquired>
        <paymentDate>01/30/2025</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>01/30/2025</noticeDate>
        <signature>/s/ Jackson Harris, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for  Brian W Ellis</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 2881}]
text: 144
  0001662008
  XXXXXXXX
  LIVE
  0000313616
  DANAHER CORP /DE/
  001-08089
  2200 PENNSYLVANIA AVE. N.W.
  SUITE 800W
  WASHINGTON
  DC
  20037-1701
  2028280850
  Ellis Brian W
  Officer
  Common
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  5700
  1277541.57
  722275141
  01/30/2025
  NYSE
  Common
  01/30/2025
  Option Granted 02/24/2016
  Issuer
  N
  5700
  01/30/2025
  Cash
  Y
  01/30/2025
  /s/ Jackson Harris, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for  Brian W Ellis