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      <submissionType>144</submissionType>
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        <filer>
          <filerCredentials>
            <cik>0001561539</cik>
            <ccc>XXXXXXXX</ccc>
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        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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      <issuerInfo>
        <issuerCik>0000059478</issuerCik>
        <issuerName>ELI LILLY &amp; Co</issuerName>
        <secFileNumber>001-06351</secFileNumber>
        <issuerAddress>
          <com:street1>LILLY CORPORATE CTR</com:street1>
          <com:street2>DROP CODE 1094</com:street2>
          <com:city>INDIANAPOLIS</com:city>
          <com:stateOrCountry>IN</com:stateOrCountry>
          <com:zipCode>46285</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>3172762000</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Zakrowski Donald A</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Merrill Lynch</name>
          <address>
            <com:street1>225 Liberty St</com:street1>
            <com:street2>Floor 37</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10281</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>900</noOfUnitsSold>
        <aggregateMarketValue>723042.00</aggregateMarketValue>
        <noOfUnitsOutstanding>949315694</noOfUnitsOutstanding>
        <approxSaleDate>11/08/2024</approxSaleDate>
        <securitiesExchangeName>NYSE</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <acquiredDate>02/12/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Vesting of performance share unit award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>ELI LILLY &amp; Co</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>900</amountOfSecuritiesAcquired>
        <paymentDate>02/12/2024</paymentDate>
        <natureOfPayment>Granted as part of issuer equity compensation plan</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Donald Zakrowski</name>
          <address>
            <com:street1>LILLY CORPORATE CTR</com:street1>
            <com:street2>DROP CODE 1094</com:street2>
            <com:city>INDIANAPOLIS</com:city>
            <com:stateOrCountry>IN</com:stateOrCountry>
            <com:zipCode>46285</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <saleDate>08/26/2024</saleDate>
        <amountOfSecuritiesSold>750</amountOfSecuritiesSold>
        <grossProceeds>712500.00</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>11/08/2024</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>11/16/2023</planAdoptionDate>
        </planAdoptionDates>
        <signature>Donald Zakrowski</signature>
      </noticeSignature>
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text: 144
  0001561539
  XXXXXXXX
  LIVE
  0000059478
  ELI LILLY & Co
  001-06351
  LILLY CORPORATE CTR
  DROP CODE 1094
  INDIANAPOLIS
  IN
  46285
  3172762000
  Zakrowski Donald A
  Officer
  Common Stock
  Merrill Lynch
  225 Liberty St
  Floor 37
  New York
  NY
  10281
  900
  723042.00
  949315694
  11/08/2024
  NYSE
  Common Stock
  02/12/2024
  Vesting of performance share unit award
  ELI LILLY & Co
  N
  900
  02/12/2024
  Granted as part of issuer equity compensation plan
  N
  Donald Zakrowski
  LILLY CORPORATE CTR
  DROP CODE 1094
  INDIANAPOLIS
  IN
  46285
  Common Stock
  08/26/2024
  750
  712500.00
  11/08/2024
  11/16/2023
  Donald Zakrowski