content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001899977</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001070494</issuerCik>
        <issuerName>ACADIA PHARMACEUTICALS INC</issuerName>
        <secFileNumber>000-50768</secFileNumber>
        <issuerAddress>
          <com:street1>3611 VALLEY CENTRE DRIVE</com:street1>
          <com:street2>SUITE 300</com:street2>
          <com:city>SAN DIEGO</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>92130</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>858-558-2871</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Schneyer Mark C.</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Piper Sandler &amp; Co.</name>
          <address>
            <com:street1>800 Nicollet Mall, Suite 900</com:street1>
            <com:city>Minneapolis</com:city>
            <com:stateOrCountry>MN</com:stateOrCountry>
            <com:zipCode>55402</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>10000</noOfUnitsSold>
        <aggregateMarketValue>293300.00</aggregateMarketValue>
        <noOfUnitsOutstanding>163728859</noOfUnitsOutstanding>
        <approxSaleDate>08/21/2023</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>06/08/2021</acquiredDate>
        <natureOfAcquisitionTransaction>Vested RSU Shares</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>333</amountOfSecuritiesAcquired>
        <paymentDate>06/08/2021</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>02/23/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Vested RSU Shares</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>799</amountOfSecuritiesAcquired>
        <paymentDate>02/23/2022</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>05/17/2023</acquiredDate>
        <natureOfAcquisitionTransaction>Vested Performance Shares</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>8868</amountOfSecuritiesAcquired>
        <paymentDate>05/17/2023</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>08/21/2023</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>03/23/2023</planAdoptionDate>
        </planAdoptionDates>
        <signature>/s/ Linda Moran, as a duly authorized representative of Piper Sandler &amp; Co Corporate &amp; Venture Services FA, as attorney-in-fact for Mark Schneyer</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 4092}]
text: 144
  0001899977
  XXXXXXXX
  LIVE
  0001070494
  ACADIA PHARMACEUTICALS INC
  000-50768
  3611 VALLEY CENTRE DRIVE
  SUITE 300
  SAN DIEGO
  CA
  92130
  858-558-2871
  Schneyer Mark C.
  Officer
  Common
  Piper Sandler & Co.
  800 Nicollet Mall, Suite 900
  Minneapolis
  MN
  55402
  10000
  293300.00
  163728859
  08/21/2023
  NASDAQ
  Common
  06/08/2021
  Vested RSU Shares
  Issuer
  N
  333
  06/08/2021
  Compensation
  Common
  02/23/2022
  Vested RSU Shares
  Issuer
  N
  799
  02/23/2022
  Compensation
  Common
  05/17/2023
  Vested Performance Shares
  Issuer
  N
  8868
  05/17/2023
  Compensation
  Y
  08/21/2023
  03/23/2023
  /s/ Linda Moran, as a duly authorized representative of Piper Sandler & Co Corporate & Venture Services FA, as attorney-in-fact for Mark Schneyer