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      <submissionType>144</submissionType>
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          <filerCredentials>
            <cik>0001567828</cik>
            <ccc>XXXXXXXX</ccc>
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        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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      <issuerInfo>
        <issuerCik>0001555280</issuerCik>
        <issuerName>Zoetis Inc.</issuerName>
        <secFileNumber>001-35797</secFileNumber>
        <issuerAddress>
          <com:street1>10 SYLVAN WAY</com:street1>
          <com:city>PARSIPPANY</com:city>
          <com:stateOrCountry>NJ</com:stateOrCountry>
          <com:zipCode>07054</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>973-822-7000</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Chen Heidi C.</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Merrill Lynch</name>
          <address>
            <com:street1>225 Liberty St</com:street1>
            <com:street2>Floor 37</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10281</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>9905</noOfUnitsSold>
        <aggregateMarketValue>1784385.75</aggregateMarketValue>
        <noOfUnitsOutstanding>460316905</noOfUnitsOutstanding>
        <approxSaleDate>09/15/2023</approxSaleDate>
        <securitiesExchangeName>NYSE</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <acquiredDate>02/12/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Vesting of restricted stock unit award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Zoetis Inc.</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>2558</amountOfSecuritiesAcquired>
        <paymentDate>02/12/2022</paymentDate>
        <natureOfPayment>Granted as part of issuer equity compensation plan</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <acquiredDate>02/12/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Vesting of performance share award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Zoetis Inc.</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>7347</amountOfSecuritiesAcquired>
        <paymentDate>02/12/2022</paymentDate>
        <natureOfPayment>Granted as part of issuer equity compensation plan</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>09/15/2023</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>06/15/2023</planAdoptionDate>
        </planAdoptionDates>
        <signature>Heidi Chen</signature>
      </noticeSignature>
    </formData>
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text: 144
  0001567828
  XXXXXXXX
  LIVE
  0001555280
  Zoetis Inc.
  001-35797
  10 SYLVAN WAY
  PARSIPPANY
  NJ
  07054
  973-822-7000
  Chen Heidi C.
  Officer
  Common Stock
  Merrill Lynch
  225 Liberty St
  Floor 37
  New York
  NY
  10281
  9905
  1784385.75
  460316905
  09/15/2023
  NYSE
  Common Stock
  02/12/2022
  Vesting of restricted stock unit award
  Zoetis Inc.
  N
  2558
  02/12/2022
  Granted as part of issuer equity compensation plan
  Common Stock
  02/12/2022
  Vesting of performance share award
  Zoetis Inc.
  N
  7347
  02/12/2022
  Granted as part of issuer equity compensation plan
  Y
  09/15/2023
  06/15/2023
  Heidi Chen