content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
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      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001909636</cik>
            <ccc>XXXXXXXX</ccc>
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        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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      <issuerInfo>
        <issuerCik>0001640266</issuerCik>
        <issuerName>Voyager Therapeutics, Inc.</issuerName>
        <secFileNumber>001-37625</secFileNumber>
        <issuerAddress>
          <com:street1>75 HAYDEN AVENUE</com:street1>
          <com:city>LEXINGTON</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>02421</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>857-259-5340</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Swartz Robin</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem Street</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>6950</noOfUnitsSold>
        <aggregateMarketValue>30937.93</aggregateMarketValue>
        <noOfUnitsOutstanding>54625586</noOfUnitsOutstanding>
        <approxSaleDate>02/11/2025</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>02/07/2025</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>6950</amountOfSecuritiesAcquired>
        <paymentDate>02/07/2025</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Robin E. Swartz</name>
          <address>
            <com:street1>75 Hayden Avenue</com:street1>
            <com:city>Lexington</com:city>
            <com:stateOrCountry>MA</com:stateOrCountry>
            <com:zipCode>02421</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>12/23/2024</saleDate>
        <amountOfSecuritiesSold>6500</amountOfSecuritiesSold>
        <grossProceeds>36747.27</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Robin E. Swartz</name>
          <address>
            <com:street1>75 Hayden Avenue</com:street1>
            <com:city>Lexington</com:city>
            <com:stateOrCountry>MA</com:stateOrCountry>
            <com:zipCode>02421</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>01/14/2025</saleDate>
        <amountOfSecuritiesSold>3087</amountOfSecuritiesSold>
        <grossProceeds>15721.47</grossProceeds>
      </securitiesSoldInPast3Months>
      <remarks>Sale includes an amount necessary to cover a tax obligation resulting from the settlement of a vested equity award distribution.</remarks>
      <noticeSignature>
        <noticeDate>02/11/2025</noticeDate>
        <signature>/s/ Daniel Tucci, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Robin Swartz</signature>
      </noticeSignature>
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text: 144
  0001909636
  XXXXXXXX
  LIVE
  0001640266
  Voyager Therapeutics, Inc.
  001-37625
  75 HAYDEN AVENUE
  LEXINGTON
  MA
  02421
  857-259-5340
  Swartz Robin
  Officer
  Common
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  6950
  30937.93
  54625586
  02/11/2025
  NASDAQ
  Common
  02/07/2025
  Restricted Stock Vesting
  Issuer
  N
  6950
  02/07/2025
  Compensation
  N
  Robin E. Swartz
  75 Hayden Avenue
  Lexington
  MA
  02421
  Common
  12/23/2024
  6500
  36747.27
  Robin E. Swartz
  75 Hayden Avenue
  Lexington
  MA
  02421
  Common
  01/14/2025
  3087
  15721.47
  Sale includes an amount necessary to cover a tax obligation resulting from the settlement of a vested equity award distribution.
  02/11/2025
  /s/ Daniel Tucci, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Robin Swartz