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            <ccc>XXXXXXXX</ccc>
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        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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        <issuerCik>0001676725</issuerCik>
        <issuerName>IDEAYA Biosciences, Inc.</issuerName>
        <secFileNumber>001-38915</secFileNumber>
        <issuerAddress>
          <com:street1>7000 Shoreline Court, Suite 350</com:street1>
          <com:city>South San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94080</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>6504436209</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Jason Throne</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>affiliate</relationshipToIssuer>
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        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>JP Morgan Securities LLC</name>
          <address>
            <com:street1>390 Madison Avenue</com:street1>
            <com:street2>6th Floor</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10019</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>4485</noOfUnitsSold>
        <aggregateMarketValue>96087</aggregateMarketValue>
        <noOfUnitsOutstanding>57290177</noOfUnitsOutstanding>
        <approxSaleDate>05/22/2023</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
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        <securitiesClassTitle>common</securitiesClassTitle>
        <acquiredDate>10/09/2019</acquiredDate>
        <natureOfAcquisitionTransaction>Stock Option exercise</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>4485</amountOfSecuritiesAcquired>
        <paymentDate>10/09/2019</paymentDate>
        <natureOfPayment>cash</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>05/22/2023</noticeDate>
        <signature>s/ JPMS LLC as agent and attorney-in-fact forJason Throne</signature>
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text: 144
  0001790865
  XXXXXXXX
  LIVE
  0001676725
  IDEAYA Biosciences, Inc.
  001-38915
  7000 Shoreline Court, Suite 350
  South San Francisco
  CA
  94080
  6504436209
  Jason Throne
  affiliate
  Common
  JP Morgan Securities LLC
  390 Madison Avenue
  6th Floor
  New York
  NY
  10019
  4485
  96087
  57290177
  05/22/2023
  NASDAQ
  common
  10/09/2019
  Stock Option exercise
  Issuer
  N
  4485
  10/09/2019
  cash
  Y
  05/22/2023
  s/ JPMS LLC as agent and attorney-in-fact forJason Throne