content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001662170</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001281895</issuerCik>
        <issuerName>ROCKET PHARMACEUTICALS, INC.</issuerName>
        <secFileNumber>001-36829</secFileNumber>
        <issuerAddress>
          <com:street1>350 FIFTH AVENUE</com:street1>
          <com:street2>SUITE 7530</com:street2>
          <com:city>NEW YORK</com:city>
          <com:stateOrCountry>NY</com:stateOrCountry>
          <com:zipCode>10118</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>646-440-9100</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Militello John</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem Street</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>2737</noOfUnitsSold>
        <aggregateMarketValue>28961.02</aggregateMarketValue>
        <noOfUnitsOutstanding>91157085</noOfUnitsOutstanding>
        <approxSaleDate>02/21/2025</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>02/14/2025</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>2737</amountOfSecuritiesAcquired>
        <paymentDate>02/14/2025</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>John Militello</name>
          <address>
            <com:street1>9 Cedarbrook Drive</com:street1>
            <com:city>Cranbury</com:city>
            <com:stateOrCountry>NJ</com:stateOrCountry>
            <com:zipCode>08512</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>11/21/2024</saleDate>
        <amountOfSecuritiesSold>1224</amountOfSecuritiesSold>
        <grossProceeds>15978.09</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>John Militello</name>
          <address>
            <com:street1>9 Cedarbrook Drive</com:street1>
            <com:city>Cranbury</com:city>
            <com:stateOrCountry>NJ</com:stateOrCountry>
            <com:zipCode>08512</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>01/23/2025</saleDate>
        <amountOfSecuritiesSold>896</amountOfSecuritiesSold>
        <grossProceeds>9300.93</grossProceeds>
      </securitiesSoldInPast3Months>
      <remarks>Sale includes an amount necessary to cover a tax obligation resulting from the settlement of a vested equity award distribution.</remarks>
      <noticeSignature>
        <noticeDate>02/21/2025</noticeDate>
        <signature>/s/ Jared Cook, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for John Militello</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
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text: 144
  0001662170
  XXXXXXXX
  LIVE
  0001281895
  ROCKET PHARMACEUTICALS, INC.
  001-36829
  350 FIFTH AVENUE
  SUITE 7530
  NEW YORK
  NY
  10118
  646-440-9100
  Militello John
  Officer
  Common
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  2737
  28961.02
  91157085
  02/21/2025
  NASDAQ
  Common
  02/14/2025
  Restricted Stock Vesting
  Issuer
  N
  2737
  02/14/2025
  Compensation
  N
  John Militello
  9 Cedarbrook Drive
  Cranbury
  NJ
  08512
  Common
  11/21/2024
  1224
  15978.09
  John Militello
  9 Cedarbrook Drive
  Cranbury
  NJ
  08512
  Common
  01/23/2025
  896
  9300.93
  Sale includes an amount necessary to cover a tax obligation resulting from the settlement of a vested equity award distribution.
  02/21/2025
  /s/ Jared Cook, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for John Militello