content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001731790</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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      <issuerInfo>
        <issuerCik>0001704292</issuerCik>
        <issuerName>Zai Lab Ltd</issuerName>
        <secFileNumber>001-38205</secFileNumber>
        <issuerAddress>
          <com:street1>4560 JINKE ROAD</com:street1>
          <com:street2>BLDG. 1, 4F, PUDONG</com:street2>
          <com:city>SHANGHAI</com:city>
          <com:stateOrCountry>F4</com:stateOrCountry>
          <com:zipCode>201210</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>862161632588</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Du Ying</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
          <relationshipToIssuer>Director</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>American Depositary Shares</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem Street</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>7013</noOfUnitsSold>
        <aggregateMarketValue>122575.32</aggregateMarketValue>
        <noOfUnitsOutstanding>758101320</noOfUnitsOutstanding>
        <approxSaleDate>07/01/2024</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>American Depositary Shares</securitiesClassTitle>
        <acquiredDate>06/28/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>7013</amountOfSecuritiesAcquired>
        <paymentDate>06/28/2024</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Samantha Ying Du</name>
          <address>
            <com:street1>4560 Jinke Road</com:street1>
            <com:street2>Bldg. 1, Fourth Floor, Pudong</com:street2>
            <com:city>Shanghai</com:city>
            <com:stateOrCountry>F4</com:stateOrCountry>
            <com:zipCode>201210</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>American Depositary Shares</securitiesClassTitle>
        <saleDate>04/02/2024</saleDate>
        <amountOfSecuritiesSold>5787</amountOfSecuritiesSold>
        <grossProceeds>93466.42</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Samantha Ying Du</name>
          <address>
            <com:street1>4560 Jinke Road</com:street1>
            <com:street2>Bldg. 1, Fourth Floor, Pudong</com:street2>
            <com:city>Shanghai</com:city>
            <com:stateOrCountry>F4</com:stateOrCountry>
            <com:zipCode>201210</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>American Depositary Shares</securitiesClassTitle>
        <saleDate>06/26/2024</saleDate>
        <amountOfSecuritiesSold>23939</amountOfSecuritiesSold>
        <grossProceeds>428539.22</grossProceeds>
      </securitiesSoldInPast3Months>
      <remarks>Sale includes an amount necessary to cover a tax obligation resulting from the settlement of a vested equity award distribution.</remarks>
      <noticeSignature>
        <noticeDate>07/01/2024</noticeDate>
        <signature>/s/ Bradley Camilo, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Samantha Ying Du</signature>
      </noticeSignature>
    </formData>
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text: 144
  0001731790
  XXXXXXXX
  LIVE
  0001704292
  Zai Lab Ltd
  001-38205
  4560 JINKE ROAD
  BLDG. 1, 4F, PUDONG
  SHANGHAI
  F4
  201210
  862161632588
  Du Ying
  Officer
  Director
  American Depositary Shares
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  7013
  122575.32
  758101320
  07/01/2024
  NASDAQ
  American Depositary Shares
  06/28/2024
  Restricted Stock Vesting
  Issuer
  N
  7013
  06/28/2024
  Compensation
  N
  Samantha Ying Du
  4560 Jinke Road
  Bldg. 1, Fourth Floor, Pudong
  Shanghai
  F4
  201210
  American Depositary Shares
  04/02/2024
  5787
  93466.42
  Samantha Ying Du
  4560 Jinke Road
  Bldg. 1, Fourth Floor, Pudong
  Shanghai
  F4
  201210
  American Depositary Shares
  06/26/2024
  23939
  428539.22
  Sale includes an amount necessary to cover a tax obligation resulting from the settlement of a vested equity award distribution.
  07/01/2024
  /s/ Bradley Camilo, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Samantha Ying Du