content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
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        <filer>
          <filerCredentials>
            <cik>0001862146</cik>
            <ccc>XXXXXXXX</ccc>
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        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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        <issuerCik>0001861560</issuerCik>
        <issuerName>Nuvalent, Inc.</issuerName>
        <secFileNumber>001-40671</secFileNumber>
        <issuerAddress>
          <com:street1>One Broadway, 14th floor</com:street1>
          <com:city>Cambridge</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>02142</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>8573577000</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Christopher Durant Turner</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>J.P. Morgan Securities LLC</name>
          <address>
            <com:street1>390 Madison Avenue</com:street1>
            <com:street2>6th Floor</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10017</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>10660</noOfUnitsSold>
        <aggregateMarketValue>517010</aggregateMarketValue>
        <noOfUnitsOutstanding>51385516</noOfUnitsOutstanding>
        <approxSaleDate>07/28/2023</approxSaleDate>
        <securitiesExchangeName>Nasdaq</securitiesExchangeName>
      </securitiesInformation>
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        <securitiesClassTitle>Class A Common</securitiesClassTitle>
        <acquiredDate>07/28/2023</acquiredDate>
        <natureOfAcquisitionTransaction>Stock Option Exercise</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>10660</amountOfSecuritiesAcquired>
        <paymentDate>07/28/2023</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Christopher Durant Turner</name>
          <address>
            <com:street1>One Broadway, 14th floor</com:street1>
            <com:city>Cambridge</com:city>
            <com:stateOrCountry>MA</com:stateOrCountry>
            <com:zipCode>02142</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Class A Common</securitiesClassTitle>
        <saleDate>06/05/2023</saleDate>
        <amountOfSecuritiesSold>10235</amountOfSecuritiesSold>
        <grossProceeds>459111</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Christopher Durant Turner</name>
          <address>
            <com:street1>One Broadway, 14th floor</com:street1>
            <com:city>Cambridge</com:city>
            <com:stateOrCountry>MA</com:stateOrCountry>
            <com:zipCode>02142</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Class A Common</securitiesClassTitle>
        <saleDate>07/20/2023</saleDate>
        <amountOfSecuritiesSold>100</amountOfSecuritiesSold>
        <grossProceeds>4680</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Christopher Durant Turner</name>
          <address>
            <com:street1>One Broadway, 14th floor</com:street1>
            <com:city>Cambridge</com:city>
            <com:stateOrCountry>MA</com:stateOrCountry>
            <com:zipCode>02142</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Class A Common</securitiesClassTitle>
        <saleDate>07/24/2023</saleDate>
        <amountOfSecuritiesSold>200</amountOfSecuritiesSold>
        <grossProceeds>9363</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Christopher Durant Turner</name>
          <address>
            <com:street1>One Broadway, 14th floor</com:street1>
            <com:city>Cambridge</com:city>
            <com:stateOrCountry>MA</com:stateOrCountry>
            <com:zipCode>02142</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Class A Common</securitiesClassTitle>
        <saleDate>07/26/2023</saleDate>
        <amountOfSecuritiesSold>2365</amountOfSecuritiesSold>
        <grossProceeds>110792</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>07/28/2023</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>10/21/2021</planAdoptionDate>
        </planAdoptionDates>
        <signature>/s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Christopher Durant Turner</signature>
      </noticeSignature>
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text: 144
  0001862146
  XXXXXXXX
  LIVE
  0001861560
  Nuvalent, Inc.
  001-40671
  One Broadway, 14th floor
  Cambridge
  MA
  02142
  8573577000
  Christopher Durant Turner
  Officer
  Common
  J.P. Morgan Securities LLC
  390 Madison Avenue
  6th Floor
  New York
  NY
  10017
  10660
  517010
  51385516
  07/28/2023
  Nasdaq
  Class A Common
  07/28/2023
  Stock Option Exercise
  Issuer
  N
  10660
  07/28/2023
  Cash
  N
  Christopher Durant Turner
  One Broadway, 14th floor
  Cambridge
  MA
  02142
  Class A Common
  06/05/2023
  10235
  459111
  Christopher Durant Turner
  One Broadway, 14th floor
  Cambridge
  MA
  02142
  Class A Common
  07/20/2023
  100
  4680
  Christopher Durant Turner
  One Broadway, 14th floor
  Cambridge
  MA
  02142
  Class A Common
  07/24/2023
  200
  9363
  Christopher Durant Turner
  One Broadway, 14th floor
  Cambridge
  MA
  02142
  Class A Common
  07/26/2023
  2365
  110792
  07/28/2023
  10/21/2021
  /s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Christopher Durant Turner