content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001662119</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001704292</issuerCik>
        <issuerName>Zai Lab Ltd</issuerName>
        <secFileNumber>001-38205</secFileNumber>
        <issuerAddress>
          <com:street1>4560 JINKE ROAD</com:street1>
          <com:street2>BLDG. 1, 4F, PUDONG</com:street2>
          <com:city>SHANGHAI</com:city>
          <com:stateOrCountry>F4</com:stateOrCountry>
          <com:zipCode>201210</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>862161632588</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Amado Rafael</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>American Depositary Shares</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem Street</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>3000</noOfUnitsSold>
        <aggregateMarketValue>115230.00</aggregateMarketValue>
        <noOfUnitsOutstanding>847651100</noOfUnitsOutstanding>
        <approxSaleDate>03/17/2025</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>American Depositary Shares</securitiesClassTitle>
        <acquiredDate>12/30/2023</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>3000</amountOfSecuritiesAcquired>
        <paymentDate>12/30/2023</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Rafael Amado</name>
          <address>
            <com:street1>4560 Jinke Road</com:street1>
            <com:street2>Bldg. 1, 4th Floor Pudong</com:street2>
            <com:city>Shanghai</com:city>
            <com:stateOrCountry>F4</com:stateOrCountry>
            <com:zipCode>201210</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>American Depositary Shares</securitiesClassTitle>
        <saleDate>12/31/2024</saleDate>
        <amountOfSecuritiesSold>7583</amountOfSecuritiesSold>
        <grossProceeds>199287.31</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>03/17/2025</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>11/22/2024</planAdoptionDate>
        </planAdoptionDates>
        <signature>/s/ Eric Janiak, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Rafael Amado</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
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text: 144
  0001662119
  XXXXXXXX
  LIVE
  0001704292
  Zai Lab Ltd
  001-38205
  4560 JINKE ROAD
  BLDG. 1, 4F, PUDONG
  SHANGHAI
  F4
  201210
  862161632588
  Amado Rafael
  Officer
  American Depositary Shares
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  3000
  115230.00
  847651100
  03/17/2025
  NASDAQ
  American Depositary Shares
  12/30/2023
  Restricted Stock Vesting
  Issuer
  N
  3000
  12/30/2023
  Compensation
  N
  Rafael Amado
  4560 Jinke Road
  Bldg. 1, 4th Floor Pudong
  Shanghai
  F4
  201210
  American Depositary Shares
  12/31/2024
  7583
  199287.31
  03/17/2025
  11/22/2024
  /s/ Eric Janiak, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Rafael Amado