content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001846045</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001107421</issuerCik>
        <issuerName>Alaunos Therapeutics, Inc.</issuerName>
        <secFileNumber>001-33038</secFileNumber>
        <issuerAddress>
          <com:street1>2617 BISSONNET ST</com:street1>
          <com:street2>SUITE 225</com:street2>
          <com:city>HOUSTON</com:city>
          <com:stateOrCountry>TX</com:stateOrCountry>
          <com:zipCode>77005</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>(346) 355-4099</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Vieser Jaime</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Director</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>245 Summer Street</com:street1>
            <com:city>Boston</com:city>
            <com:stateOrCountry>MA</com:stateOrCountry>
            <com:zipCode>02110</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>3000</noOfUnitsSold>
        <aggregateMarketValue>6510.00</aggregateMarketValue>
        <noOfUnitsOutstanding>1601252</noOfUnitsOutstanding>
        <approxSaleDate>12/31/2024</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>09/08/2017</acquiredDate>
        <natureOfAcquisitionTransaction>Open Market Purchase</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>249</amountOfSecuritiesAcquired>
        <paymentDate>09/08/2017</paymentDate>
        <natureOfPayment>Cash/ check</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>09/11/2017</acquiredDate>
        <natureOfAcquisitionTransaction>Open Market Purchase	</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>100</amountOfSecuritiesAcquired>
        <paymentDate>09/11/2017</paymentDate>
        <natureOfPayment>Cash/ check</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>09/29/2017</acquiredDate>
        <natureOfAcquisitionTransaction>Open Market Purchase	</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>333</amountOfSecuritiesAcquired>
        <paymentDate>09/29/2017</paymentDate>
        <natureOfPayment>Cash/ check</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>10/12/2017</acquiredDate>
        <natureOfAcquisitionTransaction>Open Market Purchase	</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>167</amountOfSecuritiesAcquired>
        <paymentDate>10/12/2017</paymentDate>
        <natureOfPayment>Cash/ check</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>10/13/2017</acquiredDate>
        <natureOfAcquisitionTransaction>Open Market Purchase	</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>167</amountOfSecuritiesAcquired>
        <paymentDate>10/13/2017</paymentDate>
        <natureOfPayment>Cash/ check</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common	</securitiesClassTitle>
        <acquiredDate>10/26/2017</acquiredDate>
        <natureOfAcquisitionTransaction>Open Market Purchase	</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>133</amountOfSecuritiesAcquired>
        <paymentDate>10/26/2017</paymentDate>
        <natureOfPayment>Cash/ check</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common	</securitiesClassTitle>
        <acquiredDate>11/17/2017</acquiredDate>
        <natureOfAcquisitionTransaction>Open Market Purchase	</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer	</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>147</amountOfSecuritiesAcquired>
        <paymentDate>11/17/2017</paymentDate>
        <natureOfPayment>Cash/ check</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>12/29/2017</acquiredDate>
        <natureOfAcquisitionTransaction>Open Market Purchase	</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>333</amountOfSecuritiesAcquired>
        <paymentDate>12/29/2017</paymentDate>
        <natureOfPayment>Cash/ check</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>02/05/2018</acquiredDate>
        <natureOfAcquisitionTransaction>Open Market Purchase	</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>133</amountOfSecuritiesAcquired>
        <paymentDate>02/05/2018</paymentDate>
        <natureOfPayment>Cash/ check</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>04/11/2018</acquiredDate>
        <natureOfAcquisitionTransaction>Open Market Purchase	</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>102</amountOfSecuritiesAcquired>
        <paymentDate>04/11/2018</paymentDate>
        <natureOfPayment>Cash/ check</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>04/13/2018</acquiredDate>
        <natureOfAcquisitionTransaction>Open Market Purchase	</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>133</amountOfSecuritiesAcquired>
        <paymentDate>04/13/2018</paymentDate>
        <natureOfPayment>Cash/ check</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>07/13/2018</acquiredDate>
        <natureOfAcquisitionTransaction>Open Market Purchase	</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>67</amountOfSecuritiesAcquired>
        <paymentDate>07/13/2018</paymentDate>
        <natureOfPayment>Cash/ check</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>08/02/2018</acquiredDate>
        <natureOfAcquisitionTransaction>Open Market Purchase	</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>133</amountOfSecuritiesAcquired>
        <paymentDate>08/02/2018</paymentDate>
        <natureOfPayment>Cash/ check</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>08/03/2018</acquiredDate>
        <natureOfAcquisitionTransaction>Open Market Purchase	</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>167</amountOfSecuritiesAcquired>
        <paymentDate>08/03/2018</paymentDate>
        <natureOfPayment>Cash/ check</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>08/06/2018</acquiredDate>
        <natureOfAcquisitionTransaction>Open Market Purchase	</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>67</amountOfSecuritiesAcquired>
        <paymentDate>08/06/2018</paymentDate>
        <natureOfPayment>Cash/ check</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>02/25/2019</acquiredDate>
        <natureOfAcquisitionTransaction>Open Market Purchase	</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>28</amountOfSecuritiesAcquired>
        <paymentDate>02/25/2019</paymentDate>
        <natureOfPayment>Cash/ check</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>09/25/2019</acquiredDate>
        <natureOfAcquisitionTransaction>Open Market Purchase	</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer	</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>200</amountOfSecuritiesAcquired>
        <paymentDate>09/25/2019</paymentDate>
        <natureOfPayment>Cash/ check</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>06/15/2020</acquiredDate>
        <natureOfAcquisitionTransaction>Open Market Purchase	</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>341</amountOfSecuritiesAcquired>
        <paymentDate>06/15/2020</paymentDate>
        <natureOfPayment>Cash/ check</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <remarks>Selling out of KASR LLC.</remarks>
      <noticeSignature>
        <noticeDate>12/31/2024</noticeDate>
        <signature>/s/ Cristina Garcia, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Vieser Jaime</signature>
      </noticeSignature>
    </formData>
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metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 11978}]
text: 144
  0001846045
  XXXXXXXX
  LIVE
  0001107421
  Alaunos Therapeutics, Inc.
  001-33038
  2617 BISSONNET ST
  SUITE 225
  HOUSTON
  TX
  77005
  (346) 355-4099
  Vieser Jaime
  Director
  Common
  Fidelity Brokerage Services LLC
  245 Summer Street
  Boston
  MA
  02110
  3000
  6510.00
  1601252
  12/31/2024
  NASDAQ
  Common
  09/08/2017
  Open Market Purchase
  Issuer
  N
  249
  09/08/2017
  Cash/ check
  Common
  09/11/2017
  Open Market Purchase
  Issuer
  N
  100
  09/11/2017
  Cash/ check
  Common
  09/29/2017
  Open Market Purchase
  Issuer
  N
  333
  09/29/2017
  Cash/ check
  Common
  10/12/2017
  Open Market Purchase
  Issuer
  N
  167
  10/12/2017
  Cash/ check
  Common
  10/13/2017
  Open Market Purchase
  Issuer
  N
  167
  10/13/2017
  Cash/ check
  Common
  10/26/2017
  Open Market Purchase
  Issuer
  N
  133
  10/26/2017
  Cash/ check
  Common
  11/17/2017
  Open Market Purchase
  Issuer
  N
  147
  11/17/2017
  Cash/ check
  Common
  12/29/2017
  Open Market Purchase
  Issuer
  N
  333
  12/29/2017
  Cash/ check
  Common
  02/05/2018
  Open Market Purchase
  Issuer
  N
  133
  02/05/2018
  Cash/ check
  Common
  04/11/2018
  Open Market Purchase
  Issuer
  N
  102
  04/11/2018
  Cash/ check
  Common
  04/13/2018
  Open Market Purchase
  Issuer
  N
  133
  04/13/2018
  Cash/ check
  Common
  07/13/2018
  Open Market Purchase
  Issuer
  N
  67
  07/13/2018
  Cash/ check
  Common
  08/02/2018
  Open Market Purchase
  Issuer
  N
  133
  08/02/2018
  Cash/ check
  Common
  08/03/2018
  Open Market Purchase
  Issuer
  N
  167
  08/03/2018
  Cash/ check
  Common
  08/06/2018
  Open Market Purchase
  Issuer
  N
  67
  08/06/2018
  Cash/ check
  Common
  02/25/2019
  Open Market Purchase
  Issuer
  N
  28
  02/25/2019
  Cash/ check
  Common
  09/25/2019
  Open Market Purchase
  Issuer
  N
  200
  09/25/2019
  Cash/ check
  Common
  06/15/2020
  Open Market Purchase
  Issuer
  N
  341
  06/15/2020
  Cash/ check
  Y
  Selling out of KASR LLC.
  12/31/2024
  /s/ Cristina Garcia, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Vieser Jaime