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      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001812556</cik>
            <ccc>XXXXXXXX</ccc>
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        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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      <issuerInfo>
        <issuerCik>0001645590</issuerCik>
        <issuerName>Hewlett Packard Enterprise Co</issuerName>
        <secFileNumber>001-37483</secFileNumber>
        <issuerAddress>
          <com:street1>1701 E MOSSY OAKS ROAD</com:street1>
          <com:city>SPRING</com:city>
          <com:stateOrCountry>TX</com:stateOrCountry>
          <com:zipCode>77389</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>678-259-9860</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>MacDonald Neil B</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>COMMON</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>MERRILL LYNCH</name>
          <address>
            <com:street1>3455 PEACHTREE RD NE</com:street1>
            <com:street2>SUITE 1000</com:street2>
            <com:city>ATLANTA</com:city>
            <com:stateOrCountry>GA</com:stateOrCountry>
            <com:zipCode>30326</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>17852</noOfUnitsSold>
        <aggregateMarketValue>388816.56</aggregateMarketValue>
        <noOfUnitsOutstanding>1298668639</noOfUnitsOutstanding>
        <approxSaleDate>12/12/2024</approxSaleDate>
        <securitiesExchangeName>NEW YORK</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>COMMON</securitiesClassTitle>
        <acquiredDate>12/09/2024</acquiredDate>
        <natureOfAcquisitionTransaction>RESTRICTED STOCK UNIT VEST</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>HEWLETT PACKARD ENTERPRISE COMPANY</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>16391</amountOfSecuritiesAcquired>
        <paymentDate>12/09/2024</paymentDate>
        <natureOfPayment>COMPENSATORY PAYMENT</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>COMMON</securitiesClassTitle>
        <acquiredDate>12/09/2024</acquiredDate>
        <natureOfAcquisitionTransaction>RESTRICTED STOCK UNIT VEST</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>HEWLETT PACKARD ENTERPRISE COMPANY</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>1461</amountOfSecuritiesAcquired>
        <paymentDate>12/09/2024</paymentDate>
        <natureOfPayment>COMPENSATORY PAYMENT</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>NEIL MACDONALD</name>
          <address>
            <com:street1>1701 E MOSSSY OAKS ROAD</com:street1>
            <com:city>SPRING</com:city>
            <com:stateOrCountry>TX</com:stateOrCountry>
            <com:zipCode>77389</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>COMMON</securitiesClassTitle>
        <saleDate>09/13/2024</saleDate>
        <amountOfSecuritiesSold>29000</amountOfSecuritiesSold>
        <grossProceeds>493000.00</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>NEIL MACDONALD</name>
          <address>
            <com:street1>1701 E MOSSSY OAKS ROAD</com:street1>
            <com:city>SPRING</com:city>
            <com:stateOrCountry>TX</com:stateOrCountry>
            <com:zipCode>77389</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>COMMON</securitiesClassTitle>
        <saleDate>12/10/2024</saleDate>
        <amountOfSecuritiesSold>88281</amountOfSecuritiesSold>
        <grossProceeds>2004085.13</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>NEIL MACDONALD</name>
          <address>
            <com:street1>1701 E MOSSSY OAKS ROAD</com:street1>
            <com:city>SPRING</com:city>
            <com:stateOrCountry>TX</com:stateOrCountry>
            <com:zipCode>77389</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>COMMON</securitiesClassTitle>
        <saleDate>12/11/2024</saleDate>
        <amountOfSecuritiesSold>51305</amountOfSecuritiesSold>
        <grossProceeds>1118314.62</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>12/12/2024</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>03/12/2024</planAdoptionDate>
        </planAdoptionDates>
        <signature>NEIL MACDONALD</signature>
      </noticeSignature>
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text: 144
  0001812556
  XXXXXXXX
  LIVE
  0001645590
  Hewlett Packard Enterprise Co
  001-37483
  1701 E MOSSY OAKS ROAD
  SPRING
  TX
  77389
  678-259-9860
  MacDonald Neil B
  Officer
  COMMON
  MERRILL LYNCH
  3455 PEACHTREE RD NE
  SUITE 1000
  ATLANTA
  GA
  30326
  17852
  388816.56
  1298668639
  12/12/2024
  NEW YORK
  COMMON
  12/09/2024
  RESTRICTED STOCK UNIT VEST
  HEWLETT PACKARD ENTERPRISE COMPANY
  N
  16391
  12/09/2024
  COMPENSATORY PAYMENT
  COMMON
  12/09/2024
  RESTRICTED STOCK UNIT VEST
  HEWLETT PACKARD ENTERPRISE COMPANY
  N
  1461
  12/09/2024
  COMPENSATORY PAYMENT
  N
  NEIL MACDONALD
  1701 E MOSSSY OAKS ROAD
  SPRING
  TX
  77389
  COMMON
  09/13/2024
  29000
  493000.00
  NEIL MACDONALD
  1701 E MOSSSY OAKS ROAD
  SPRING
  TX
  77389
  COMMON
  12/10/2024
  88281
  2004085.13
  NEIL MACDONALD
  1701 E MOSSSY OAKS ROAD
  SPRING
  TX
  77389
  COMMON
  12/11/2024
  51305
  1118314.62
  12/12/2024
  03/12/2024
  NEIL MACDONALD