content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
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      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001430462</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
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      <issuerInfo>
        <issuerCik>0001756262</issuerCik>
        <issuerName>TransMedics Group, Inc.</issuerName>
        <secFileNumber>001-38891</secFileNumber>
        <issuerAddress>
          <com:street1>20 Minuteman Rd</com:street1>
          <com:city>Andover</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>01810</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>9785520900</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Tamer Khayal</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Chief Commercial Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>JPMorgan Securiites LLC</name>
          <address>
            <com:street1>390 Madison Ave</com:street1>
            <com:street2>6th Floor</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10017</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>5000</noOfUnitsSold>
        <aggregateMarketValue>403750</aggregateMarketValue>
        <noOfUnitsOutstanding>32196219</noOfUnitsOutstanding>
        <approxSaleDate>04/21/2023</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>05/31/2013</acquiredDate>
        <natureOfAcquisitionTransaction>Stock option exercise</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>5000</amountOfSecuritiesAcquired>
        <paymentDate>05/31/2013</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Khayal Family 2021 Irrevocable Trust</name>
          <address>
            <com:street1>20 Minuteman Rd</com:street1>
            <com:city>Andover</com:city>
            <com:stateOrCountry>MA</com:stateOrCountry>
            <com:zipCode>01810</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Shares</securitiesClassTitle>
        <saleDate>03/01/2023</saleDate>
        <amountOfSecuritiesSold>5000</amountOfSecuritiesSold>
        <grossProceeds>400309</grossProceeds>
      </securitiesSoldInPast3Months>
      <remarks>Shares were sold for the  Khayal Family 2021 Irrev Trust</remarks>
      <noticeSignature>
        <noticeDate>04/21/2023</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>01/11/2023</planAdoptionDate>
        </planAdoptionDates>
        <signature>/s/ JPMS LLC as agent and attorney-in-fact for Tamer Khayal</signature>
      </noticeSignature>
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text: 144
  0001430462
  XXXXXXXX
  LIVE
  0001756262
  TransMedics Group, Inc.
  001-38891
  20 Minuteman Rd
  Andover
  MA
  01810
  9785520900
  Tamer Khayal
  Chief Commercial Officer
  Common
  JPMorgan Securiites LLC
  390 Madison Ave
  6th Floor
  New York
  NY
  10017
  5000
  403750
  32196219
  04/21/2023
  NASDAQ
  Common
  05/31/2013
  Stock option exercise
  Issuer
  N
  5000
  05/31/2013
  Cash
  N
  Khayal Family 2021 Irrevocable Trust
  20 Minuteman Rd
  Andover
  MA
  01810
  Common Shares
  03/01/2023
  5000
  400309
  Shares were sold for the  Khayal Family 2021 Irrev Trust
  04/21/2023
  01/11/2023
  /s/ JPMS LLC as agent and attorney-in-fact for Tamer Khayal