content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001674404</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001025835</issuerCik>
        <issuerName>ENTERPRISE FINANCIAL SERVICES CORP</issuerName>
        <secFileNumber>001-15373</secFileNumber>
        <issuerAddress>
          <com:street1>150 NORTH MERAMEC</com:street1>
          <com:street2>150 NORTH MERAMEC</com:street2>
          <com:city>CLAYTON</com:city>
          <com:stateOrCountry>MO</com:stateOrCountry>
          <com:zipCode>63105</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>3147255500</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>LALLY JAMES BRIAN</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
          <relationshipToIssuer>Director</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem Street</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>400</noOfUnitsSold>
        <aggregateMarketValue>22004.00</aggregateMarketValue>
        <noOfUnitsOutstanding>36932680</noOfUnitsOutstanding>
        <approxSaleDate>05/15/2025</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>01/30/2023</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>400</amountOfSecuritiesAcquired>
        <paymentDate>01/30/2023</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>James Lally</name>
          <address>
            <com:street1>150 North Meramec</com:street1>
            <com:city>Clayton</com:city>
            <com:stateOrCountry>MO</com:stateOrCountry>
            <com:zipCode>63105</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>05/13/2025</saleDate>
        <amountOfSecuritiesSold>2206</amountOfSecuritiesSold>
        <grossProceeds>121411.50</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>James Lally</name>
          <address>
            <com:street1>150 North Meramec</com:street1>
            <com:city>Clayton</com:city>
            <com:stateOrCountry>MO</com:stateOrCountry>
            <com:zipCode>63105</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>05/12/2025</saleDate>
        <amountOfSecuritiesSold>4689</amountOfSecuritiesSold>
        <grossProceeds>258757.14</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>05/15/2025</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>12/17/2024</planAdoptionDate>
        </planAdoptionDates>
        <signature>/s/ Joshua Schmitt, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for James B. Lally.</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
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text: 144
  0001674404
  XXXXXXXX
  LIVE
  0001025835
  ENTERPRISE FINANCIAL SERVICES CORP
  001-15373
  150 NORTH MERAMEC
  150 NORTH MERAMEC
  CLAYTON
  MO
  63105
  3147255500
  LALLY JAMES BRIAN
  Officer
  Director
  Common
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  400
  22004.00
  36932680
  05/15/2025
  NASDAQ
  Common
  01/30/2023
  Restricted Stock Vesting
  Issuer
  N
  400
  01/30/2023
  Compensation
  N
  James Lally
  150 North Meramec
  Clayton
  MO
  63105
  Common
  05/13/2025
  2206
  121411.50
  James Lally
  150 North Meramec
  Clayton
  MO
  63105
  Common
  05/12/2025
  4689
  258757.14
  05/15/2025
  12/17/2024
  /s/ Joshua Schmitt, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for James B. Lally.