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            <ccc>XXXXXXXX</ccc>
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        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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        <issuerName>Medtronic plc</issuerName>
        <secFileNumber>001-36820</secFileNumber>
        <issuerAddress>
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          <com:stateOrCountry>L2</com:stateOrCountry>
          <com:zipCode>1</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>01135314381700</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>PARKHILL KAREN L</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Former Director</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem Street</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
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        <aggregateMarketValue>1358740.32</aggregateMarketValue>
        <noOfUnitsOutstanding>1282490493</noOfUnitsOutstanding>
        <approxSaleDate>10/30/2024</approxSaleDate>
        <securitiesExchangeName>NYSE</securitiesExchangeName>
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        <acquiredDate>10/30/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Option Granted- 07/30/2018</natureOfAcquisitionTransaction>
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        <isGiftTransaction>N</isGiftTransaction>
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        <paymentDate>10/30/2024</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Karen L. Parkhill</name>
          <address>
            <com:street1>Building Two</com:street1>
            <com:street2>Parkmore Business Park West</com:street2>
            <com:city>Galway</com:city>
            <com:stateOrCountry>L2</com:stateOrCountry>
            <com:zipCode>1</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>08/26/2024</saleDate>
        <amountOfSecuritiesSold>2668</amountOfSecuritiesSold>
        <grossProceeds>240120.00</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Karen L. Parkhill</name>
          <address>
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            <com:stateOrCountry>L2</com:stateOrCountry>
            <com:zipCode>1</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>10/17/2024</saleDate>
        <amountOfSecuritiesSold>55179</amountOfSecuritiesSold>
        <grossProceeds>4958715.22</grossProceeds>
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      <securitiesSoldInPast3Months>
        <sellerDetails>
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          <address>
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            <com:stateOrCountry>L2</com:stateOrCountry>
            <com:zipCode>1</com:zipCode>
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        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>10/18/2024</saleDate>
        <amountOfSecuritiesSold>48825</amountOfSecuritiesSold>
        <grossProceeds>4479309.77</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Karen L. ParkhillKaren L. Parkhill</name>
          <address>
            <com:street1>Building Two</com:street1>
            <com:street2>Parkmore Business Park West</com:street2>
            <com:city>Galway</com:city>
            <com:stateOrCountry>L2</com:stateOrCountry>
            <com:zipCode>1</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>10/23/2024</saleDate>
        <amountOfSecuritiesSold>23848</amountOfSecuritiesSold>
        <grossProceeds>2188206.17</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Karen L. Parkhill</name>
          <address>
            <com:street1>Building Two</com:street1>
            <com:street2>Parkmore Business Park West</com:street2>
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            <com:stateOrCountry>L2</com:stateOrCountry>
            <com:zipCode>1</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>10/24/2024</saleDate>
        <amountOfSecuritiesSold>22712</amountOfSecuritiesSold>
        <grossProceeds>2100632.88</grossProceeds>
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        <sellerDetails>
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          <address>
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            <com:stateOrCountry>L2</com:stateOrCountry>
            <com:zipCode>1</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>10/29/2024</saleDate>
        <amountOfSecuritiesSold>15000</amountOfSecuritiesSold>
        <grossProceeds>1367347.50</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>10/30/2024</noticeDate>
        <signature>/s/Wade Moss, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Karen L Parkhill</signature>
      </noticeSignature>
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text: 144
  0001527660
  XXXXXXXX
  LIVE
  0001613103
  Medtronic plc
  001-36820
  BUILDING TWO PARKMORE BUSINESS PARK WEST
  GALWAY
  L2
  1
  01135314381700
  PARKHILL KAREN L
  Former Director
  Common
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  15000
  1358740.32
  1282490493
  10/30/2024
  NYSE
  Common
  10/30/2024
  Option Granted- 07/30/2018
  Issuer
  N
  15000
  10/30/2024
  Cash
  N
  Karen L. Parkhill
  Building Two
  Parkmore Business Park West
  Galway
  L2
  1
  Common
  08/26/2024
  2668
  240120.00
  Karen L. Parkhill
  Building Two
  Parkmore Business Park West
  Galway
  L2
  1
  Common
  10/17/2024
  55179
  4958715.22
  Karen L. Parkhill
  Building Two
  Parkmore Business Park West
  Galway
  L2
  1
  Common
  10/18/2024
  48825
  4479309.77
  Karen L. ParkhillKaren L. Parkhill
  Building Two
  Parkmore Business Park West
  Galway
  L2
  1
  Common
  10/23/2024
  23848
  2188206.17
  Karen L. Parkhill
  Building Two
  Parkmore Business Park West
  Galway
  L2
  1
  Common
  10/24/2024
  22712
  2100632.88
  Karen L. Parkhill
  Building Two
  Parkmore Business Park West
  Galway
  L2
  1
  Common
  10/29/2024
  15000
  1367347.50
  10/30/2024
  /s/Wade Moss, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Karen L Parkhill