content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001777217</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001668397</issuerCik>
        <issuerName>Medpace Holdings, Inc.</issuerName>
        <secFileNumber>001-37856</secFileNumber>
        <issuerAddress>
          <com:street1>5375 MEDPACE WAY</com:street1>
          <com:city>CINCINNATI</com:city>
          <com:stateOrCountry>OH</com:stateOrCountry>
          <com:zipCode>45227</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>(513) 579-9911</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Keating Ashley M.</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Former Director</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem Street</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>2000</noOfUnitsSold>
        <aggregateMarketValue>765000.00</aggregateMarketValue>
        <noOfUnitsOutstanding>31001761</noOfUnitsOutstanding>
        <approxSaleDate>08/06/2024</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>08/06/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Option Granted 05/20/2022</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>1000</amountOfSecuritiesAcquired>
        <paymentDate>08/06/2024</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>08/06/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Option Granted 05/19/2023</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>1000</amountOfSecuritiesAcquired>
        <paymentDate>08/06/2024</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Ashley M. Keating</name>
          <address>
            <com:street1>5375 Medpace Way</com:street1>
            <com:city>Cincinnati</com:city>
            <com:stateOrCountry>OH</com:stateOrCountry>
            <com:zipCode>45227</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>07/25/2024</saleDate>
        <amountOfSecuritiesSold>2422</amountOfSecuritiesSold>
        <grossProceeds>934377.45</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Ashley M. Keating</name>
          <address>
            <com:street1>5375 Medpace Way</com:street1>
            <com:city>Cincinnati</com:city>
            <com:stateOrCountry>OH</com:stateOrCountry>
            <com:zipCode>45227</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>07/30/2024</saleDate>
        <amountOfSecuritiesSold>1300</amountOfSecuritiesSold>
        <grossProceeds>506600.00</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>08/06/2024</noticeDate>
        <signature>/s/ Eric Janiak, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Ashley M. Keating</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 4543}]
text: 144
  0001777217
  XXXXXXXX
  LIVE
  0001668397
  Medpace Holdings, Inc.
  001-37856
  5375 MEDPACE WAY
  CINCINNATI
  OH
  45227
  (513) 579-9911
  Keating Ashley M.
  Former Director
  Common
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  2000
  765000.00
  31001761
  08/06/2024
  NASDAQ
  Common
  08/06/2024
  Option Granted 05/20/2022
  Issuer
  N
  1000
  08/06/2024
  Cash
  Common
  08/06/2024
  Option Granted 05/19/2023
  Issuer
  N
  1000
  08/06/2024
  Cash
  N
  Ashley M. Keating
  5375 Medpace Way
  Cincinnati
  OH
  45227
  Common
  07/25/2024
  2422
  934377.45
  Ashley M. Keating
  5375 Medpace Way
  Cincinnati
  OH
  45227
  Common
  07/30/2024
  1300
  506600.00
  08/06/2024
  /s/ Eric Janiak, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Ashley M. Keating