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        <paymentDate>05/20/2021</paymentDate>
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      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
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        <paymentDate>01/01/2022</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
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      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
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        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
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        <paymentDate>08/20/2020</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>07/22/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
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        <paymentDate>07/22/2024</paymentDate>
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        <paymentDate>04/01/2022</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
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      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>07/01/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
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        <paymentDate>07/01/2024</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
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        <securitiesClassTitle>Common</securitiesClassTitle>
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        <paymentDate>01/01/2025</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
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        <securitiesClassTitle>Common</securitiesClassTitle>
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        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
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        <paymentDate>02/20/2025</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
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        <securitiesClassTitle>Common</securitiesClassTitle>
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        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
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        <paymentDate>11/08/2024</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
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        <sellerDetails>
          <name>Patrick Finn</name>
          <address>
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            <com:city>South San Francisco</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>94080</com:zipCode>
          </address>
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        <sellerDetails>
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            <com:zipCode>94080</com:zipCode>
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        <securitiesClassTitle>Common</securitiesClassTitle>
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        <grossProceeds>7978.98</grossProceeds>
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        <sellerDetails>
          <name>Patrick Finn</name>
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            <com:zipCode>94080</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
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        <grossProceeds>82310.53</grossProceeds>
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        <sellerDetails>
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      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>05/08/2025</noticeDate>
        <signature>/s/ Daniel Tucci, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Patrick Finn</signature>
      </noticeSignature>
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text: 144
  0001755970
  XXXXXXXX
  LIVE
  0001581280
  Twist Bioscience Corp
  001-38720
  681 GATEWAY BLVD.
  SOUTH SAN FRANCISCO
  CA
  94080
  800-719-0671
  Finn Patrick John
  Officer
  Common
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  20000
  646256.55
  59916141
  05/08/2025
  NASDAQ
  Common
  01/24/2021
  Restricted Stock Vesting
  Issuer
  N
  378
  01/24/2021
  Compensation
  Common
  02/20/2021
  Restricted Stock Vesting
  Issuer
  N
  923
  02/20/2021
  Compensation
  Common
  01/04/2021
  Restricted Stock Vesting
  Issuer
  N
  292
  01/04/2021
  Compensation
  Common
  04/24/2021
  Restricted Stock Vesting
  Issuer
  N
  274
  04/24/2021
  Compensation
  Common
  07/01/2021
  Restricted Stock Vesting
  Issuer
  N
  230
  07/01/2021
  Compensation
  Common
  04/01/2021
  Restricted Stock Vesting
  Issuer
  N
  230
  04/01/2021
  Compensation
  Common
  07/24/2021
  Restricted Stock Vesting
  Issuer
  N
  274
  07/24/2021
  Compensation
  Common
  10/24/2021
  Restricted Stock Vesting
  Issuer
  N
  274
  10/24/2021
  Compensation
  Common
  11/20/2020
  Restricted Stock Vesting
  Issuer
  N
  983
  11/20/2020
  Compensation
  Common
  11/20/2021
  Restricted Stock Vesting
  Issuer
  N
  923
  11/20/2021
  Compensation
  Common
  10/01/2021
  Restricted Stock Vesting
  Issuer
  N
  230
  10/01/2021
  Compensation
  Common
  08/20/2021
  Restricted Stock Vesting
  Issuer
  N
  923
  08/20/2021
  Compensation
  Common
  05/20/2021
  Restricted Stock Vesting
  Issuer
  N
  923
  05/20/2021
  Compensation
  Common
  10/24/2020
  Restricted Stock Vesting
  Issuer
  N
  1168
  10/24/2020
  Compensation
  Common
  01/01/2022
  Restricted Stock Vesting
  Issuer
  N
  362
  01/01/2022
  Compensation
  Common
  08/20/2020
  Restricted Stock Vesting
  Issuer
  N
  983
  08/20/2020
  Compensation
  Common
  07/22/2024
  Restricted Stock Vesting
  Issuer
  N
  1925
  07/22/2024
  Compensation
  Common
  01/22/2025
  Restricted Stock Vesting
  Issuer
  N
  1710
  01/22/2025
  Compensation
  Common
  01/24/2022
  Restricted Stock Vesting
  Issuer
  N
  243
  01/24/2022
  Compensation
  Common
  02/02/2025
  Restricted Stock Vesting
  Issuer
  N
  2141
  02/02/2025
  Compensation
  Common
  02/20/2022
  Restricted Stock Vesting
  Issuer
  N
  923
  02/20/2022
  Compensation
  Common
  04/01/2022
  Restricted Stock Vesting
  Issuer
  N
  408
  04/01/2022
  Compensation
  Common
  07/01/2024
  Restricted Stock Vesting
  Issuer
  N
  390
  07/01/2024
  Compensation
  Common
  01/01/2025
  Restricted Stock Vesting
  Issuer
  N
  150
  01/01/2025
  Compensation
  Common
  02/20/2025
  Restricted Stock Vesting
  Issuer
  N
  1513
  02/20/2025
  Compensation
  Common
  11/08/2024
  Restricted Stock Vesting
  Issuer
  N
  1227
  11/08/2024
  Compensation
  N
  Patrick Finn
  681 Gateway Blvd
  South San Francisco
  CA
  94080
  Common
  02/21/2025
  1839
  81241.14
  Patrick Finn
  681 Gateway Blvd.
  South San Francisco
  CA
  94080
  Common
  04/02/2025
  206
  7978.98
  Patrick Finn
  681 Gateway Blvd.
  South San Francisco
  CA
  94080
  Common
  04/23/2025
  2058
  82310.53
  Patrick Finn
  681 Gateway Blvd.
  South San Francisco
  CA
  94080
  Common
  05/05/2025
  2800
  105422.80
  05/08/2025
  /s/ Daniel Tucci, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Patrick Finn