content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001229143</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0000723531</issuerCik>
        <issuerName>PAYCHEX INC</issuerName>
        <secFileNumber>000-11330</secFileNumber>
        <issuerAddress>
          <com:street1>911 PANORAMA TRAIL S</com:street1>
          <com:city>ROCHESTER</com:city>
          <com:stateOrCountry>NY</com:stateOrCountry>
          <com:zipCode>14625-0397</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>5853856666</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>FLASCHEN DAVID J S</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Director</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem Street</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>14434</noOfUnitsSold>
        <aggregateMarketValue>1807257.33</aggregateMarketValue>
        <noOfUnitsOutstanding>360126911</noOfUnitsOutstanding>
        <approxSaleDate>08/05/2024</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>08/05/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Options Granted - 07/12/2018</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>8641</amountOfSecuritiesAcquired>
        <paymentDate>08/05/2024</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>08/05/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Options Granted - 07/15/2020</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>5793</amountOfSecuritiesAcquired>
        <paymentDate>08/05/2024</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>David Flaschen</name>
          <address>
            <com:street1>911 Panorama Trail South</com:street1>
            <com:city>Rochester</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>14625-2396</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>05/24/2024</saleDate>
        <amountOfSecuritiesSold>19709</amountOfSecuritiesSold>
        <grossProceeds>2454670.69</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>David Flaschen</name>
          <address>
            <com:street1>911 Panorama Trail South</com:street1>
            <com:city>Rochester</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>14625-2396</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>07/26/2024</saleDate>
        <amountOfSecuritiesSold>9615</amountOfSecuritiesSold>
        <grossProceeds>1207677.65</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>08/05/2024</noticeDate>
        <signature>/s/ Jared Cook, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for David Flaschen</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 4556}]
text: 144
  0001229143
  XXXXXXXX
  LIVE
  0000723531
  PAYCHEX INC
  000-11330
  911 PANORAMA TRAIL S
  ROCHESTER
  NY
  14625-0397
  5853856666
  FLASCHEN DAVID J S
  Director
  Common
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  14434
  1807257.33
  360126911
  08/05/2024
  NASDAQ
  Common
  08/05/2024
  Options Granted - 07/12/2018
  Issuer
  N
  8641
  08/05/2024
  Cash
  Common
  08/05/2024
  Options Granted - 07/15/2020
  Issuer
  N
  5793
  08/05/2024
  Cash
  N
  David Flaschen
  911 Panorama Trail South
  Rochester
  NY
  14625-2396
  Common
  05/24/2024
  19709
  2454670.69
  David Flaschen
  911 Panorama Trail South
  Rochester
  NY
  14625-2396
  Common
  07/26/2024
  9615
  1207677.65
  08/05/2024
  /s/ Jared Cook, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for David Flaschen