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      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001443841</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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        <issuerCik>0001267565</issuerCik>
        <issuerName>COLLEGIUM PHARMACEUTICAL, INC</issuerName>
        <secFileNumber>001-37372</secFileNumber>
        <issuerAddress>
          <com:street1>100 TECHNOLOGY CENTER DRIVE</com:street1>
          <com:city>STOUGHTON</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>02072</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>781-713-3699</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Ciaffoni Joseph</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Former Officer &amp; Director</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem Street</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>84313</noOfUnitsSold>
        <aggregateMarketValue>2660030.35</aggregateMarketValue>
        <noOfUnitsOutstanding>32715322</noOfUnitsOutstanding>
        <approxSaleDate>06/04/2024</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>02/12/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>84313</amountOfSecuritiesAcquired>
        <paymentDate>02/12/2024</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Joseph J. Ciaffoni</name>
          <address>
            <com:street1>100 Technology Center Drive</com:street1>
            <com:city>Stoughton</com:city>
            <com:stateOrCountry>MA</com:stateOrCountry>
            <com:zipCode>02072</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>05/28/2024</saleDate>
        <amountOfSecuritiesSold>48992</amountOfSecuritiesSold>
        <grossProceeds>1675729.02</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Joseph J. Ciaffoni</name>
          <address>
            <com:street1>100 Technology Center Drive</com:street1>
            <com:city>Stoughton</com:city>
            <com:stateOrCountry>MA</com:stateOrCountry>
            <com:zipCode>02072</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>05/29/2024</saleDate>
        <amountOfSecuritiesSold>54146</amountOfSecuritiesSold>
        <grossProceeds>1803484.15</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Joseph J. Ciaffoni</name>
          <address>
            <com:street1>100 Technology Center Drive</com:street1>
            <com:city>Stoughton</com:city>
            <com:stateOrCountry>MA</com:stateOrCountry>
            <com:zipCode>02072</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>05/30/2024</saleDate>
        <amountOfSecuritiesSold>54147</amountOfSecuritiesSold>
        <grossProceeds>1794269.97</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Joseph J. Ciaffoni</name>
          <address>
            <com:street1>100 Technology Center Drive</com:street1>
            <com:city>Stoughton</com:city>
            <com:stateOrCountry>MA</com:stateOrCountry>
            <com:zipCode>02072</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>06/03/2024</saleDate>
        <amountOfSecuritiesSold>52572</amountOfSecuritiesSold>
        <grossProceeds>1709001.84</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>06/04/2024</noticeDate>
        <signature>/s/Wade Moss, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Joseph J Ciaffoni </signature>
      </noticeSignature>
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text: 144
  0001443841
  XXXXXXXX
  LIVE
  0001267565
  COLLEGIUM PHARMACEUTICAL, INC
  001-37372
  100 TECHNOLOGY CENTER DRIVE
  STOUGHTON
  MA
  02072
  781-713-3699
  Ciaffoni Joseph
  Former Officer & Director
  Common
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  84313
  2660030.35
  32715322
  06/04/2024
  NASDAQ
  Common
  02/12/2024
  Restricted Stock Vesting
  Issuer
  N
  84313
  02/12/2024
  Compensation
  N
  Joseph J. Ciaffoni
  100 Technology Center Drive
  Stoughton
  MA
  02072
  Common
  05/28/2024
  48992
  1675729.02
  Joseph J. Ciaffoni
  100 Technology Center Drive
  Stoughton
  MA
  02072
  Common
  05/29/2024
  54146
  1803484.15
  Joseph J. Ciaffoni
  100 Technology Center Drive
  Stoughton
  MA
  02072
  Common
  05/30/2024
  54147
  1794269.97
  Joseph J. Ciaffoni
  100 Technology Center Drive
  Stoughton
  MA
  02072
  Common
  06/03/2024
  52572
  1709001.84
  06/04/2024
  /s/Wade Moss, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Joseph J Ciaffoni