content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001835824</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001704292</issuerCik>
        <issuerName>Zai Lab Ltd</issuerName>
        <secFileNumber>001-38205</secFileNumber>
        <issuerAddress>
          <com:street1>4560 JINKE ROAD</com:street1>
          <com:street2>BLDG. 1, 4F, PUDONG</com:street2>
          <com:city>SHANGHAI</com:city>
          <com:stateOrCountry>F4</com:stateOrCountry>
          <com:zipCode>201210</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>862161632588</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Reinhart Harald</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Former Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>American Depositary Shares</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem Street</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>60000</noOfUnitsSold>
        <aggregateMarketValue>1320000.00</aggregateMarketValue>
        <noOfUnitsOutstanding>762101560</noOfUnitsOutstanding>
        <approxSaleDate>09/26/2024</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>American Depositary Shares</securitiesClassTitle>
        <acquiredDate>09/26/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Options Granted - 03/28/2018</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>60000</amountOfSecuritiesAcquired>
        <paymentDate>09/26/2024</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Harald Reinhart</name>
          <address>
            <com:street1>4560 Jinke Road</com:street1>
            <com:street2>Bldg. 1, Fourth Floor, Pudong</com:street2>
            <com:city>Shanghai</com:city>
            <com:stateOrCountry>F4</com:stateOrCountry>
            <com:zipCode>201210</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>American Depositary Shares</securitiesClassTitle>
        <saleDate>06/26/2024</saleDate>
        <amountOfSecuritiesSold>7431</amountOfSecuritiesSold>
        <grossProceeds>133024.59</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Harald Reinhart</name>
          <address>
            <com:street1>4560 Jinke Road</com:street1>
            <com:street2>Bldg. 1, Fourth Floor, Pudong</com:street2>
            <com:city>Shanghai</com:city>
            <com:stateOrCountry>F4</com:stateOrCountry>
            <com:zipCode>201210</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>American Depositary Shares</securitiesClassTitle>
        <saleDate>09/19/2024</saleDate>
        <amountOfSecuritiesSold>70000</amountOfSecuritiesSold>
        <grossProceeds>1481095.00</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>09/26/2024</noticeDate>
        <signature>/s/ Gerardo Ibarra-Munoz, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Harald H. Reinhart</signature>
      </noticeSignature>
    </formData>
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text: 144
  0001835824
  XXXXXXXX
  LIVE
  0001704292
  Zai Lab Ltd
  001-38205
  4560 JINKE ROAD
  BLDG. 1, 4F, PUDONG
  SHANGHAI
  F4
  201210
  862161632588
  Reinhart Harald
  Former Officer
  American Depositary Shares
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  60000
  1320000.00
  762101560
  09/26/2024
  NASDAQ
  American Depositary Shares
  09/26/2024
  Options Granted - 03/28/2018
  Issuer
  N
  60000
  09/26/2024
  Cash
  N
  Harald Reinhart
  4560 Jinke Road
  Bldg. 1, Fourth Floor, Pudong
  Shanghai
  F4
  201210
  American Depositary Shares
  06/26/2024
  7431
  133024.59
  Harald Reinhart
  4560 Jinke Road
  Bldg. 1, Fourth Floor, Pudong
  Shanghai
  F4
  201210
  American Depositary Shares
  09/19/2024
  70000
  1481095.00
  09/26/2024
  /s/ Gerardo Ibarra-Munoz, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Harald H. Reinhart