content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001798744</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001376339</issuerCik>
        <issuerName>MIMEDX GROUP, INC.</issuerName>
        <secFileNumber>001-35887</secFileNumber>
        <issuerAddress>
          <com:street1>1775 W OAK COMMONS COURT, NE</com:street1>
          <com:city>MARIETTA</com:city>
          <com:stateOrCountry>GA</com:stateOrCountry>
          <com:zipCode>30062</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>(770) 651-9100</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Whitlow Ricci S</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem Street</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>15271</noOfUnitsSold>
        <aggregateMarketValue>122343.62</aggregateMarketValue>
        <noOfUnitsOutstanding>116376583</noOfUnitsOutstanding>
        <approxSaleDate>02/20/2024</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>02/16/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>15271</amountOfSecuritiesAcquired>
        <paymentDate>02/16/2024</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Ricci Whitlow</name>
          <address>
            <com:street1>1775 West Oak Commons Ct NE</com:street1>
            <com:city>Marietta</com:city>
            <com:stateOrCountry>GA</com:stateOrCountry>
            <com:zipCode>30062</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>02/14/2024</saleDate>
        <amountOfSecuritiesSold>15845</amountOfSecuritiesSold>
        <grossProceeds>127274.96</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Ricci Whitlow</name>
          <address>
            <com:street1>1775 West Oak Commons Ct NE</com:street1>
            <com:city>Marietta</com:city>
            <com:stateOrCountry>GA</com:stateOrCountry>
            <com:zipCode>30062</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>02/15/2024</saleDate>
        <amountOfSecuritiesSold>15198</amountOfSecuritiesSold>
        <grossProceeds>122488.28</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Ricci Whitlow</name>
          <address>
            <com:street1>1775 West Oak Commons Ct NE</com:street1>
            <com:city>Marietta</com:city>
            <com:stateOrCountry>GA</com:stateOrCountry>
            <com:zipCode>30062</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>02/16/2024</saleDate>
        <amountOfSecuritiesSold>15493</amountOfSecuritiesSold>
        <grossProceeds>125076.54</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>02/20/2024</noticeDate>
        <signature>/s/ Ryan Riviere, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Ricci Whitlow</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 4619}]
text: 144
  0001798744
  XXXXXXXX
  LIVE
  0001376339
  MIMEDX GROUP, INC.
  001-35887
  1775 W OAK COMMONS COURT, NE
  MARIETTA
  GA
  30062
  (770) 651-9100
  Whitlow Ricci S
  Officer
  Common
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  15271
  122343.62
  116376583
  02/20/2024
  NASDAQ
  Common
  02/16/2024
  Restricted Stock Vesting
  Issuer
  N
  15271
  02/16/2024
  Compensation
  N
  Ricci Whitlow
  1775 West Oak Commons Ct NE
  Marietta
  GA
  30062
  Common
  02/14/2024
  15845
  127274.96
  Ricci Whitlow
  1775 West Oak Commons Ct NE
  Marietta
  GA
  30062
  Common
  02/15/2024
  15198
  122488.28
  Ricci Whitlow
  1775 West Oak Commons Ct NE
  Marietta
  GA
  30062
  Common
  02/16/2024
  15493
  125076.54
  02/20/2024
  /s/ Ryan Riviere, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Ricci Whitlow