content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001920061</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001192448</issuerCik>
        <issuerName>GLAUKOS Corp</issuerName>
        <secFileNumber>001-37463</secFileNumber>
        <issuerAddress>
          <com:street1>1 GLAUKOS WAY</com:street1>
          <com:city>ALISO VIEJO</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>92656</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>949-367-9600</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Thurman Alex R.</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem St</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>316</noOfUnitsSold>
        <aggregateMarketValue>29901.38</aggregateMarketValue>
        <noOfUnitsOutstanding>49470423</noOfUnitsOutstanding>
        <approxSaleDate>04/03/2024</approxSaleDate>
        <securitiesExchangeName>NYSE</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>03/22/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>52</amountOfSecuritiesAcquired>
        <paymentDate>03/22/2024</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>04/01/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>264</amountOfSecuritiesAcquired>
        <paymentDate>04/01/2024</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Alex R. Thurman</name>
          <address>
            <com:street1>One Glaukos Way</com:street1>
            <com:city>Aliso Viejo</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>92656</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>01/18/2024</saleDate>
        <amountOfSecuritiesSold>583</amountOfSecuritiesSold>
        <grossProceeds>52784.81</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Alex R. Thurman</name>
          <address>
            <com:street1>One Glaukos Way</com:street1>
            <com:city>Aliso Viejo</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>92656</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>02/07/2024</saleDate>
        <amountOfSecuritiesSold>33</amountOfSecuritiesSold>
        <grossProceeds>3135.00</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Alex R. Thurman</name>
          <address>
            <com:street1>One Glaukos Way,</com:street1>
            <com:city>Aliso Viejo,</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>92656</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>02/08/2024</saleDate>
        <amountOfSecuritiesSold>550</amountOfSecuritiesSold>
        <grossProceeds>52681.35</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Alex R. Thurman</name>
          <address>
            <com:street1>One Glaukos Way,</com:street1>
            <com:city>Aliso Viejo</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>92656</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>04/02/2024</saleDate>
        <amountOfSecuritiesSold>474</amountOfSecuritiesSold>
        <grossProceeds>42835.05</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>04/03/2024</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>05/17/2023</planAdoptionDate>
        </planAdoptionDates>
        <signature>/s/ Jennifer Ruchti, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Alex R. Thurman</signature>
      </noticeSignature>
    </formData>
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text: 144
  0001920061
  XXXXXXXX
  LIVE
  0001192448
  GLAUKOS Corp
  001-37463
  1 GLAUKOS WAY
  ALISO VIEJO
  CA
  92656
  949-367-9600
  Thurman Alex R.
  Officer
  Common
  Fidelity Brokerage Services LLC
  900 Salem St
  Smithfield
  RI
  02917
  316
  29901.38
  49470423
  04/03/2024
  NYSE
  Common
  03/22/2024
  Restricted Stock Vesting
  Issuer
  N
  52
  03/22/2024
  Compensation
  Common
  04/01/2024
  Restricted Stock Vesting
  Issuer
  N
  264
  04/01/2024
  Compensation
  N
  Alex R. Thurman
  One Glaukos Way
  Aliso Viejo
  CA
  92656
  Common
  01/18/2024
  583
  52784.81
  Alex R. Thurman
  One Glaukos Way
  Aliso Viejo
  CA
  92656
  Common
  02/07/2024
  33
  3135.00
  Alex R. Thurman
  One Glaukos Way,
  Aliso Viejo,
  CA
  92656
  Common
  02/08/2024
  550
  52681.35
  Alex R. Thurman
  One Glaukos Way,
  Aliso Viejo
  CA
  92656
  Common
  04/02/2024
  474
  42835.05
  04/03/2024
  05/17/2023
  /s/ Jennifer Ruchti, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Alex R. Thurman