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        <filer>
          <filerCredentials>
            <cik>0001869027</cik>
            <ccc>XXXXXXXX</ccc>
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        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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      <issuerInfo>
        <issuerCik>0001623526</issuerCik>
        <issuerName>Stoke Therapeutics Inc</issuerName>
        <secFileNumber>001-38938</secFileNumber>
        <issuerAddress>
          <com:street1>45 Wiggins Avenue</com:street1>
          <com:city>Bedford</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>01730</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>781-430-8200</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Ezbon International Limited</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Affiliate</relationshipToIssuer>
        </relationshipsToIssuer>
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      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>J.P. Morgan Securities LLC</name>
          <address>
            <com:street1>390 Madison Avenue - 6th Floor</com:street1>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10017</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>3600000</noOfUnitsSold>
        <aggregateMarketValue>41760000</aggregateMarketValue>
        <noOfUnitsOutstanding>46303743</noOfUnitsOutstanding>
        <approxSaleDate>04/17/2024</approxSaleDate>
        <securitiesExchangeName>Nasdaq</securitiesExchangeName>
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        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>06/29/2021</acquiredDate>
        <natureOfAcquisitionTransaction>Distribution in Kind</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>ATP Life Science Ventures, L.P.</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>7605577</amountOfSecuritiesAcquired>
        <paymentDate>06/29/2021</paymentDate>
        <natureOfPayment>N/A</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>04/17/2024</noticeDate>
        <signature>/s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Ezbon International Limited</signature>
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text: 144
  0001869027
  XXXXXXXX
  LIVE
  0001623526
  Stoke Therapeutics Inc
  001-38938
  45 Wiggins Avenue
  Bedford
  MA
  01730
  781-430-8200
  Ezbon International Limited
  Affiliate
  Common
  J.P. Morgan Securities LLC
  390 Madison Avenue - 6th Floor
  New York
  NY
  10017
  3600000
  41760000
  46303743
  04/17/2024
  Nasdaq
  Common
  06/29/2021
  Distribution in Kind
  ATP Life Science Ventures, L.P.
  N
  7605577
  06/29/2021
  N/A
  Y
  04/17/2024
  /s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Ezbon International Limited