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      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001916332</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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    <formData>
      <issuerInfo>
        <issuerCik>0000350698</issuerCik>
        <issuerName>AUTONATION, INC.</issuerName>
        <secFileNumber>001-13107</secFileNumber>
        <issuerAddress>
          <com:street1>200 SW 1ST AVE</com:street1>
          <com:street2>SUITE 1600</com:street2>
          <com:city>FORT LAUDERDALE</com:city>
          <com:stateOrCountry>FL</com:stateOrCountry>
          <com:zipCode>33301</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>9547696000</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>KWAK STEVE</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Former Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Merrill Lynch</name>
          <address>
            <com:street1>3455 Peachtree Road NE</com:street1>
            <com:street2>Suite 1000</com:street2>
            <com:city>Atlanta</com:city>
            <com:stateOrCountry>GA</com:stateOrCountry>
            <com:zipCode>30326</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>7955</noOfUnitsSold>
        <aggregateMarketValue>1005295.93</aggregateMarketValue>
        <noOfUnitsOutstanding>42520469</noOfUnitsOutstanding>
        <approxSaleDate>10/30/2023</approxSaleDate>
        <securitiesExchangeName>NYSE</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>03/01/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Vesting of a Stock Award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Autonation, Inc.</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>3845</amountOfSecuritiesAcquired>
        <paymentDate>03/01/2022</paymentDate>
        <natureOfPayment>Compensatory Payment</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>03/01/2023</acquiredDate>
        <natureOfAcquisitionTransaction>Vesting of a Stock Award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Autonation, Inc.</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>3617</amountOfSecuritiesAcquired>
        <paymentDate>03/01/2023</paymentDate>
        <natureOfPayment>Compensatory Payment</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>03/08/2023</acquiredDate>
        <natureOfAcquisitionTransaction>Vesting of a Stock Award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Autonation, Inc.</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>493</amountOfSecuritiesAcquired>
        <paymentDate>03/08/2023</paymentDate>
        <natureOfPayment>Compensatory Payment</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>10/30/2023</noticeDate>
        <signature>STEVE KWAK</signature>
      </noticeSignature>
    </formData>
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text: 144
  0001916332
  XXXXXXXX
  LIVE
  0000350698
  AUTONATION, INC.
  001-13107
  200 SW 1ST AVE
  SUITE 1600
  FORT LAUDERDALE
  FL
  33301
  9547696000
  KWAK STEVE
  Former Officer
  Common
  Merrill Lynch
  3455 Peachtree Road NE
  Suite 1000
  Atlanta
  GA
  30326
  7955
  1005295.93
  42520469
  10/30/2023
  NYSE
  Common
  03/01/2022
  Vesting of a Stock Award
  Autonation, Inc.
  N
  3845
  03/01/2022
  Compensatory Payment
  Common
  03/01/2023
  Vesting of a Stock Award
  Autonation, Inc.
  N
  3617
  03/01/2023
  Compensatory Payment
  Common
  03/08/2023
  Vesting of a Stock Award
  Autonation, Inc.
  N
  493
  03/08/2023
  Compensatory Payment
  Y
  10/30/2023
  STEVE KWAK