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            <cik>0001771383</cik>
            <ccc>XXXXXXXX</ccc>
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        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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      <issuerInfo>
        <issuerCik>0000721371</issuerCik>
        <issuerName>CARDINAL HEALTH INC</issuerName>
        <secFileNumber>001-11373</secFileNumber>
        <issuerAddress>
          <com:street1>7000 CARDINAL PLACE</com:street1>
          <com:city>DUBLIN</com:city>
          <com:stateOrCountry>OH</com:stateOrCountry>
          <com:zipCode>43017</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>6147573033</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Mayer Jessica L</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Merrill</name>
          <address>
            <com:street1>8890 Lyra Dr 5th Flr</com:street1>
            <com:city>Columbus</com:city>
            <com:stateOrCountry>OH</com:stateOrCountry>
            <com:zipCode>43240</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>30145</noOfUnitsSold>
        <aggregateMarketValue>2738364.00</aggregateMarketValue>
        <noOfUnitsOutstanding>250681620</noOfUnitsOutstanding>
        <approxSaleDate>08/16/2023</approxSaleDate>
        <securitiesExchangeName>NYSE</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>08/15/2023</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted stock vest</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Cardinal Health</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>6130</amountOfSecuritiesAcquired>
        <paymentDate>08/15/2023</paymentDate>
        <natureOfPayment>NA</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>common</securitiesClassTitle>
        <acquiredDate>08/15/2014</acquiredDate>
        <natureOfAcquisitionTransaction>Stock option exercise</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Cardinal Health</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>1142</amountOfSecuritiesAcquired>
        <paymentDate>08/16/2023</paymentDate>
        <natureOfPayment>cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>common</securitiesClassTitle>
        <acquiredDate>08/15/2015</acquiredDate>
        <natureOfAcquisitionTransaction>stock option exercise</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Cardinal Health</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>973</amountOfSecuritiesAcquired>
        <paymentDate>08/16/2023</paymentDate>
        <natureOfPayment>cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>common</securitiesClassTitle>
        <acquiredDate>09/01/2013</acquiredDate>
        <natureOfAcquisitionTransaction>restricted stock vest</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Cardinal Health</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>12</amountOfSecuritiesAcquired>
        <paymentDate>09/01/2013</paymentDate>
        <natureOfPayment>na</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>common</securitiesClassTitle>
        <acquiredDate>09/01/2014</acquiredDate>
        <natureOfAcquisitionTransaction>restricted stock vest</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Cardinal Health</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>536</amountOfSecuritiesAcquired>
        <paymentDate>09/10/2014</paymentDate>
        <natureOfPayment>na</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>common</securitiesClassTitle>
        <acquiredDate>09/01/2015</acquiredDate>
        <natureOfAcquisitionTransaction>restricted stock vest</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Cardinal Health</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>527</amountOfSecuritiesAcquired>
        <paymentDate>09/01/2015</paymentDate>
        <natureOfPayment>na</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>common</securitiesClassTitle>
        <acquiredDate>08/15/2016</acquiredDate>
        <natureOfAcquisitionTransaction>restricted stock vest</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Cardinal Health</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>168</amountOfSecuritiesAcquired>
        <paymentDate>08/15/2016</paymentDate>
        <natureOfPayment>na</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>ommon</securitiesClassTitle>
        <acquiredDate>09/01/2016</acquiredDate>
        <natureOfAcquisitionTransaction>restricted stock vest</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Cardinal Health</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>307</amountOfSecuritiesAcquired>
        <paymentDate>09/01/2016</paymentDate>
        <natureOfPayment>na</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>common</securitiesClassTitle>
        <acquiredDate>08/15/2017</acquiredDate>
        <natureOfAcquisitionTransaction>restricted stock vest</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Cardinal Health</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>445</amountOfSecuritiesAcquired>
        <paymentDate>08/15/2017</paymentDate>
        <natureOfPayment>na</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>common</securitiesClassTitle>
        <acquiredDate>08/15/2020</acquiredDate>
        <natureOfAcquisitionTransaction>restricted stock vest</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Cardinal Health</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>5434</amountOfSecuritiesAcquired>
        <paymentDate>08/15/2020</paymentDate>
        <natureOfPayment>na</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>common</securitiesClassTitle>
        <acquiredDate>03/15/2021</acquiredDate>
        <natureOfAcquisitionTransaction>restricted stock vest</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Cardinal Health</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>119</amountOfSecuritiesAcquired>
        <paymentDate>03/15/2021</paymentDate>
        <natureOfPayment>na</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>common</securitiesClassTitle>
        <acquiredDate>08/15/2022</acquiredDate>
        <natureOfAcquisitionTransaction>restricted stock vest</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Cardinal Health</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>14352</amountOfSecuritiesAcquired>
        <paymentDate>08/15/2022</paymentDate>
        <natureOfPayment>na</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>08/16/2023</noticeDate>
        <signature>Jessica Mayer</signature>
      </noticeSignature>
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text: 144
  0001771383
  XXXXXXXX
  LIVE
  0000721371
  CARDINAL HEALTH INC
  001-11373
  7000 CARDINAL PLACE
  DUBLIN
  OH
  43017
  6147573033
  Mayer Jessica L
  Officer
  Common
  Merrill
  8890 Lyra Dr 5th Flr
  Columbus
  OH
  43240
  30145
  2738364.00
  250681620
  08/16/2023
  NYSE
  Common
  08/15/2023
  Restricted stock vest
  Cardinal Health
  N
  6130
  08/15/2023
  NA
  common
  08/15/2014
  Stock option exercise
  Cardinal Health
  N
  1142
  08/16/2023
  cash
  common
  08/15/2015
  stock option exercise
  Cardinal Health
  N
  973
  08/16/2023
  cash
  common
  09/01/2013
  restricted stock vest
  Cardinal Health
  N
  12
  09/01/2013
  na
  common
  09/01/2014
  restricted stock vest
  Cardinal Health
  N
  536
  09/10/2014
  na
  common
  09/01/2015
  restricted stock vest
  Cardinal Health
  N
  527
  09/01/2015
  na
  common
  08/15/2016
  restricted stock vest
  Cardinal Health
  N
  168
  08/15/2016
  na
  ommon
  09/01/2016
  restricted stock vest
  Cardinal Health
  N
  307
  09/01/2016
  na
  common
  08/15/2017
  restricted stock vest
  Cardinal Health
  N
  445
  08/15/2017
  na
  common
  08/15/2020
  restricted stock vest
  Cardinal Health
  N
  5434
  08/15/2020
  na
  common
  03/15/2021
  restricted stock vest
  Cardinal Health
  N
  119
  03/15/2021
  na
  common
  08/15/2022
  restricted stock vest
  Cardinal Health
  N
  14352
  08/15/2022
  na
  Y
  08/16/2023
  Jessica Mayer