content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001493858</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001374310</issuerCik>
        <issuerName>CBOE Global Markets, Inc</issuerName>
        <secFileNumber>001-34774</secFileNumber>
        <issuerAddress>
          <com:street1>433 West Van Buren st</com:street1>
          <com:city>Chicago</com:city>
          <com:stateOrCountry>IL</com:stateOrCountry>
          <com:zipCode>60607</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>3127865600</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Tilly Edward T</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Rockefeller Financial LLC</name>
          <address>
            <com:street1>227 W Monroe St</com:street1>
            <com:street2>STE 2050</com:street2>
            <com:city>Chicago</com:city>
            <com:stateOrCountry>IL</com:stateOrCountry>
            <com:zipCode>60010</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>50000</noOfUnitsSold>
        <aggregateMarketValue>8282770.00</aggregateMarketValue>
        <noOfUnitsOutstanding>105555989</noOfUnitsOutstanding>
        <approxSaleDate>11/03/2023</approxSaleDate>
        <securitiesExchangeName>other</securitiesExchangeName>
      </securitiesInformation>
      <securitiesInformation>
        <securitiesClassTitle>common (call contact)</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Rockefeller Financial LLC</name>
          <address>
            <com:street1>227 W Monroe St</com:street1>
            <com:street2>STE 2050</com:street2>
            <com:city>chicago</com:city>
            <com:stateOrCountry>IL</com:stateOrCountry>
            <com:zipCode>60010</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>10000</noOfUnitsSold>
        <aggregateMarketValue>1700000.00</aggregateMarketValue>
        <noOfUnitsOutstanding>105555989</noOfUnitsOutstanding>
        <approxSaleDate>11/03/2023</approxSaleDate>
        <securitiesExchangeName>other</securitiesExchangeName>
      </securitiesInformation>
      <securitiesInformation>
        <securitiesClassTitle>common (call contact)</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Rockefeller Financial LLC</name>
          <address>
            <com:street1>227 W Monroe St</com:street1>
            <com:street2>STE 2050</com:street2>
            <com:city>Chicago</com:city>
            <com:stateOrCountry>IL</com:stateOrCountry>
            <com:zipCode>60010</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>5000</noOfUnitsSold>
        <aggregateMarketValue>850000.00</aggregateMarketValue>
        <noOfUnitsOutstanding>105555989</noOfUnitsOutstanding>
        <approxSaleDate>11/03/2023</approxSaleDate>
        <securitiesExchangeName>other</securitiesExchangeName>
      </securitiesInformation>
      <securitiesInformation>
        <securitiesClassTitle>common (call contact)</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Rockefeller Financial LLC</name>
          <address>
            <com:street1>227 W Monroe St</com:street1>
            <com:street2>STE 2050</com:street2>
            <com:city>Chicago</com:city>
            <com:stateOrCountry>IL</com:stateOrCountry>
            <com:zipCode>60010</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>5000</noOfUnitsSold>
        <aggregateMarketValue>850000.00</aggregateMarketValue>
        <noOfUnitsOutstanding>105555989</noOfUnitsOutstanding>
        <approxSaleDate>11/03/2023</approxSaleDate>
        <securitiesExchangeName>other</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>common (50k shares)</securitiesClassTitle>
        <acquiredDate>02/19/2022</acquiredDate>
        <natureOfAcquisitionTransaction>stock award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>12959</amountOfSecuritiesAcquired>
        <paymentDate>02/19/2022</paymentDate>
        <natureOfPayment>cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>common (50k shares)</securitiesClassTitle>
        <acquiredDate>02/09/2022</acquiredDate>
        <natureOfAcquisitionTransaction>stock award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>6090</amountOfSecuritiesAcquired>
        <paymentDate>02/09/2022</paymentDate>
        <natureOfPayment>cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>common (50k shares)</securitiesClassTitle>
        <acquiredDate>02/19/2020</acquiredDate>
        <natureOfAcquisitionTransaction>stock award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>16046</amountOfSecuritiesAcquired>
        <paymentDate>02/19/2020</paymentDate>
        <natureOfPayment>cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>common (50k shares)</securitiesClassTitle>
        <acquiredDate>02/10/2020</acquiredDate>
        <natureOfAcquisitionTransaction>stock award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>2822</amountOfSecuritiesAcquired>
        <paymentDate>02/10/2020</paymentDate>
        <natureOfPayment>cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>common (50k shares)</securitiesClassTitle>
        <acquiredDate>02/21/2018</acquiredDate>
        <natureOfAcquisitionTransaction>stock award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>12083</amountOfSecuritiesAcquired>
        <paymentDate>02/21/2018</paymentDate>
        <natureOfPayment>cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>common (20k call shares)</securitiesClassTitle>
        <acquiredDate>02/21/2018</acquiredDate>
        <natureOfAcquisitionTransaction>stock award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>3904</amountOfSecuritiesAcquired>
        <paymentDate>02/21/2018</paymentDate>
        <natureOfPayment>cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>common (20k call shares)</securitiesClassTitle>
        <acquiredDate>02/26/2018</acquiredDate>
        <natureOfAcquisitionTransaction>stock award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>5533</amountOfSecuritiesAcquired>
        <paymentDate>02/26/2018</paymentDate>
        <natureOfPayment>cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>common (20k call shares)</securitiesClassTitle>
        <acquiredDate>02/20/2018</acquiredDate>
        <natureOfAcquisitionTransaction>stock award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>8989</amountOfSecuritiesAcquired>
        <paymentDate>02/20/2018</paymentDate>
        <natureOfPayment>cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>common (20k call shares)</securitiesClassTitle>
        <acquiredDate>02/27/2018</acquiredDate>
        <natureOfAcquisitionTransaction>stock award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>1305</amountOfSecuritiesAcquired>
        <paymentDate>02/27/2018</paymentDate>
        <natureOfPayment>cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>common (20k call shares)</securitiesClassTitle>
        <acquiredDate>02/19/2021</acquiredDate>
        <natureOfAcquisitionTransaction>stock award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>269</amountOfSecuritiesAcquired>
        <paymentDate>02/19/2021</paymentDate>
        <natureOfPayment>cash</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <remarks>20,000 shares represent common shares to possibly be sold via 3 listed call option transactions executed on 11/3/2023;
  S 100 Call contracts 12/15/23 expiry $170 strike
  S 50 Call contracts 12/23/23 expiry $170 strike
  S 50 Call contracts 1/19/23 expiry $170 strike</remarks>
      <noticeSignature>
        <noticeDate>11/03/2023</noticeDate>
        <signature>Jason Coleman as a duly authorized representative of National Financial Services LLC, as attorney-in-fact for Edward Tilly</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 10327}]
text: 144
  0001493858
  XXXXXXXX
  LIVE
  0001374310
  CBOE Global Markets, Inc
  001-34774
  433 West Van Buren st
  Chicago
  IL
  60607
  3127865600
  Tilly Edward T
  Officer
  Common
  Rockefeller Financial LLC
  227 W Monroe St
  STE 2050
  Chicago
  IL
  60010
  50000
  8282770.00
  105555989
  11/03/2023
  other
  common (call contact)
  Rockefeller Financial LLC
  227 W Monroe St
  STE 2050
  chicago
  IL
  60010
  10000
  1700000.00
  105555989
  11/03/2023
  other
  common (call contact)
  Rockefeller Financial LLC
  227 W Monroe St
  STE 2050
  Chicago
  IL
  60010
  5000
  850000.00
  105555989
  11/03/2023
  other
  common (call contact)
  Rockefeller Financial LLC
  227 W Monroe St
  STE 2050
  Chicago
  IL
  60010
  5000
  850000.00
  105555989
  11/03/2023
  other
  common (50k shares)
  02/19/2022
  stock award
  issuer
  N
  12959
  02/19/2022
  cash
  common (50k shares)
  02/09/2022
  stock award
  issuer
  N
  6090
  02/09/2022
  cash
  common (50k shares)
  02/19/2020
  stock award
  issuer
  N
  16046
  02/19/2020
  cash
  common (50k shares)
  02/10/2020
  stock award
  issuer
  N
  2822
  02/10/2020
  cash
  common (50k shares)
  02/21/2018
  stock award
  issuer
  N
  12083
  02/21/2018
  cash
  common (20k call shares)
  02/21/2018
  stock award
  issuer
  N
  3904
  02/21/2018
  cash
  common (20k call shares)
  02/26/2018
  stock award
  issuer
  N
  5533
  02/26/2018
  cash
  common (20k call shares)
  02/20/2018
  stock award
  issuer
  N
  8989
  02/20/2018
  cash
  common (20k call shares)
  02/27/2018
  stock award
  issuer
  N
  1305
  02/27/2018
  cash
  common (20k call shares)
  02/19/2021
  stock award
  issuer
  N
  269
  02/19/2021
  cash
  Y
  20,000 shares represent common shares to possibly be sold via 3 listed call option transactions executed on 11/3/2023;
  S 100 Call contracts 12/15/23 expiry $170 strike
  S 50 Call contracts 12/23/23 expiry $170 strike
  S 50 Call contracts 1/19/23 expiry $170 strike
  11/03/2023
  Jason Coleman as a duly authorized representative of National Financial Services LLC, as attorney-in-fact for Edward Tilly