content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
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      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001977434</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0000946581</issuerCik>
        <issuerName>TAKE TWO INTERACTIVE SOFTWARE INC</issuerName>
        <secFileNumber>001-34003</secFileNumber>
        <issuerAddress>
          <com:street1>110 WEST 44TH STREET</com:street1>
          <com:city>NEW YORK</com:city>
          <com:stateOrCountry>NY</com:stateOrCountry>
          <com:zipCode>10036</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>646 536 2842</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>ZMC Advisors, L.P.</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Affiliate</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Merrill Lynch, Pierce, Fenner &amp; Smith Incorporated</name>
          <address>
            <com:street1>555 California Street</com:street1>
            <com:city>San Francisco</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>94104</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>216661</noOfUnitsSold>
        <aggregateMarketValue>49470206.13</aggregateMarketValue>
        <noOfUnitsOutstanding>177424908</noOfUnitsOutstanding>
        <approxSaleDate>05/30/2025</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>06/01/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Performance Share Awards</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>163638</amountOfSecuritiesAcquired>
        <paymentDate>05/30/2025</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>06/01/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>25201</amountOfSecuritiesAcquired>
        <paymentDate>05/30/2025</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>06/01/2023</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>13543</amountOfSecuritiesAcquired>
        <paymentDate>05/30/2025</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>06/03/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>14279</amountOfSecuritiesAcquired>
        <paymentDate>05/30/2025</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <remarks>Sales under 10b5-1 Plan to pay taxes upon vesting of restricted units</remarks>
      <noticeSignature>
        <noticeDate>05/30/2025</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>11/13/2024</planAdoptionDate>
        </planAdoptionDates>
        <signature>Strauss Zelnick</signature>
      </noticeSignature>
    </formData>
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text: 144
  0001977434
  XXXXXXXX
  LIVE
  0000946581
  TAKE TWO INTERACTIVE SOFTWARE INC
  001-34003
  110 WEST 44TH STREET
  NEW YORK
  NY
  10036
  646 536 2842
  ZMC Advisors, L.P.
  Affiliate
  Common
  Merrill Lynch, Pierce, Fenner & Smith Incorporated
  555 California Street
  San Francisco
  CA
  94104
  216661
  49470206.13
  177424908
  05/30/2025
  NASDAQ
  Common
  06/01/2022
  Performance Share Awards
  Issuer
  N
  163638
  05/30/2025
  Compensation
  Common
  06/01/2022
  Restricted Stock Vesting
  Issuer
  N
  25201
  05/30/2025
  Compensation
  Common
  06/01/2023
  Restricted Stock Vesting
  Issuer
  N
  13543
  05/30/2025
  Compensation
  Common
  06/03/2024
  Restricted Stock Vesting
  Issuer
  N
  14279
  05/30/2025
  Compensation
  Y
  Sales under 10b5-1 Plan to pay taxes upon vesting of restricted units
  05/30/2025
  11/13/2024
  Strauss Zelnick