content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001869672</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0000059478</issuerCik>
        <issuerName>ELI LILLY &amp; Co</issuerName>
        <secFileNumber>001-06351</secFileNumber>
        <issuerAddress>
          <com:street1>LILLY CORPORATE CTR</com:street1>
          <com:street2>DROP CODE 1094</com:street2>
          <com:city>INDIANAPOLIS</com:city>
          <com:stateOrCountry>IN</com:stateOrCountry>
          <com:zipCode>46285</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>3172762000</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Weems Alonzo</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Merrill Lynch</name>
          <address>
            <com:street1>225 Liberty St</com:street1>
            <com:street2>Floor 37</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10281</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>1148</noOfUnitsSold>
        <aggregateMarketValue>678445.04</aggregateMarketValue>
        <noOfUnitsOutstanding>949295173</noOfUnitsOutstanding>
        <approxSaleDate>09/12/2023</approxSaleDate>
        <securitiesExchangeName>NYSE</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <acquiredDate>02/09/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Vesting of restricted stock unit award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>ELI LILLY &amp; Co</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>1148</amountOfSecuritiesAcquired>
        <paymentDate>02/09/2022</paymentDate>
        <natureOfPayment>Granted as part of issuer equity compensation plan</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>09/12/2023</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>06/14/2023</planAdoptionDate>
        </planAdoptionDates>
        <signature>Alonzo Weems</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 2971}]
text: 144
  0001869672
  XXXXXXXX
  LIVE
  0000059478
  ELI LILLY & Co
  001-06351
  LILLY CORPORATE CTR
  DROP CODE 1094
  INDIANAPOLIS
  IN
  46285
  3172762000
  Weems Alonzo
  Officer
  Common Stock
  Merrill Lynch
  225 Liberty St
  Floor 37
  New York
  NY
  10281
  1148
  678445.04
  949295173
  09/12/2023
  NYSE
  Common Stock
  02/09/2022
  Vesting of restricted stock unit award
  ELI LILLY & Co
  N
  1148
  02/09/2022
  Granted as part of issuer equity compensation plan
  Y
  09/12/2023
  06/14/2023
  Alonzo Weems