content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
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    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001649119</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001676725</issuerCik>
        <issuerName>IDEAYA Biosciences, Inc.</issuerName>
        <secFileNumber>001-38915</secFileNumber>
        <issuerAddress>
          <com:street1>7000 Shoreline Court</com:street1>
          <com:street2>Suite 350</com:street2>
          <com:city>San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94080</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>6504436209</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>YUJIRO HATA</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>CEO</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>J.P. Morgan Securities LLC</name>
          <address>
            <com:street1>390 Madison Avenue</com:street1>
            <com:street2>6th Floor</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10017</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>75000</noOfUnitsSold>
        <aggregateMarketValue>3000000</aggregateMarketValue>
        <noOfUnitsOutstanding>64459472</noOfUnitsOutstanding>
        <approxSaleDate>01/12/2024</approxSaleDate>
        <securitiesExchangeName>Nasdaq</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>01/12/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Stock Option Exercise</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>75000</amountOfSecuritiesAcquired>
        <paymentDate>01/12/2024</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Yujiro Hata</name>
          <address>
            <com:street1>7000 Shoreline Court</com:street1>
            <com:street2>Suite 350</com:street2>
            <com:city>San Francisco</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>94080</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>12/15/2023</saleDate>
        <amountOfSecuritiesSold>75000</amountOfSecuritiesSold>
        <grossProceeds>2627619</grossProceeds>
      </securitiesSoldInPast3Months>
      <remarks>The sales under this filing are from Cashless Option Exercises that will occur within 3 months from the date of filings.</remarks>
      <noticeSignature>
        <noticeDate>01/12/2024</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>05/11/2023</planAdoptionDate>
        </planAdoptionDates>
        <signature>/s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Yujiro Hata</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
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text: 144
  0001649119
  XXXXXXXX
  LIVE
  0001676725
  IDEAYA Biosciences, Inc.
  001-38915
  7000 Shoreline Court
  Suite 350
  San Francisco
  CA
  94080
  6504436209
  YUJIRO HATA
  CEO
  Common
  J.P. Morgan Securities LLC
  390 Madison Avenue
  6th Floor
  New York
  NY
  10017
  75000
  3000000
  64459472
  01/12/2024
  Nasdaq
  Common
  01/12/2024
  Stock Option Exercise
  Issuer
  N
  75000
  01/12/2024
  Cash
  N
  Yujiro Hata
  7000 Shoreline Court
  Suite 350
  San Francisco
  CA
  94080
  Common
  12/15/2023
  75000
  2627619
  The sales under this filing are from Cashless Option Exercises that will occur within 3 months from the date of filings.
  01/12/2024
  05/11/2023
  /s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Yujiro Hata