content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001375889</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001321732</issuerCik>
        <issuerName>Penumbra Inc</issuerName>
        <secFileNumber>001-37557</secFileNumber>
        <issuerAddress>
          <com:street1>ONE PENUMBRA PLACE</com:street1>
          <com:city>ALAMEDA</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94502</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>(510) 995-2486</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Grewal Harpreet</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Director</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>245 Summer Street</com:street1>
            <com:city>Boston</com:city>
            <com:stateOrCountry>MA</com:stateOrCountry>
            <com:zipCode>02110</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>170</noOfUnitsSold>
        <aggregateMarketValue>40968.30</aggregateMarketValue>
        <noOfUnitsOutstanding>38436663</noOfUnitsOutstanding>
        <approxSaleDate>10/02/2023</approxSaleDate>
        <securitiesExchangeName>NYSE</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <acquiredDate>09/30/2023</acquiredDate>
        <natureOfAcquisitionTransaction>Stock Award vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Penumbra, Inc.</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>170</amountOfSecuritiesAcquired>
        <paymentDate>09/30/2023</paymentDate>
        <natureOfPayment>N/A</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Harpreet Grewal</name>
          <address>
            <com:street1>c/o Penumbra, Inc</com:street1>
            <com:street2>One Penumbra Place</com:street2>
            <com:city>Alameda</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>94502</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <saleDate>09/01/2023</saleDate>
        <amountOfSecuritiesSold>340</amountOfSecuritiesSold>
        <grossProceeds>90650.80</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>10/02/2023</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>05/23/2023</planAdoptionDate>
        </planAdoptionDates>
        <signature>/s/ Myra King, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Harpreet Grewal</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 3571}]
text: 144
  0001375889
  XXXXXXXX
  LIVE
  0001321732
  Penumbra Inc
  001-37557
  ONE PENUMBRA PLACE
  ALAMEDA
  CA
  94502
  (510) 995-2486
  Grewal Harpreet
  Director
  Common Stock
  Fidelity Brokerage Services LLC
  245 Summer Street
  Boston
  MA
  02110
  170
  40968.30
  38436663
  10/02/2023
  NYSE
  Common Stock
  09/30/2023
  Stock Award vesting
  Penumbra, Inc.
  N
  170
  09/30/2023
  N/A
  N
  Harpreet Grewal
  c/o Penumbra, Inc
  One Penumbra Place
  Alameda
  CA
  94502
  Common Stock
  09/01/2023
  340
  90650.80
  10/02/2023
  05/23/2023
  /s/ Myra King, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Harpreet Grewal