content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001473812</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001613103</issuerCik>
        <issuerName>Medtronic plc</issuerName>
        <secFileNumber>001-36820</secFileNumber>
        <issuerAddress>
          <com:street1>BUILDING TWO PARKMORE BUSINESS PARK WEST</com:street1>
          <com:city>GALWAY</com:city>
          <com:stateOrCountry>L2</com:stateOrCountry>
          <com:zipCode>1</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>01135314381700</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Wall Brett A.</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem Street</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>12437</noOfUnitsSold>
        <aggregateMarketValue>1119330.00</aggregateMarketValue>
        <noOfUnitsOutstanding>1282285681</noOfUnitsOutstanding>
        <approxSaleDate>01/24/2025</approxSaleDate>
        <securitiesExchangeName>NYSE</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>01/24/2025</acquiredDate>
        <natureOfAcquisitionTransaction>Options Granted 08/03/2015</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>12437</amountOfSecuritiesAcquired>
        <paymentDate>01/24/2025</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Brett Wall</name>
          <address>
            <com:street1>Building Two</com:street1>
            <com:street2>Parkmore Business Park West</com:street2>
            <com:city>Galway</com:city>
            <com:stateOrCountry>L2</com:stateOrCountry>
            <com:zipCode>-</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>01/08/2025</saleDate>
        <amountOfSecuritiesSold>9850</amountOfSecuritiesSold>
        <grossProceeds>792038.50</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>01/24/2025</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>10/10/2024</planAdoptionDate>
        </planAdoptionDates>
        <signature>/s/ Jennifer Ruchti, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Brett Wall</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
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text: 144
  0001473812
  XXXXXXXX
  LIVE
  0001613103
  Medtronic plc
  001-36820
  BUILDING TWO PARKMORE BUSINESS PARK WEST
  GALWAY
  L2
  1
  01135314381700
  Wall Brett A.
  Officer
  Common
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  12437
  1119330.00
  1282285681
  01/24/2025
  NYSE
  Common
  01/24/2025
  Options Granted 08/03/2015
  Issuer
  N
  12437
  01/24/2025
  Cash
  N
  Brett Wall
  Building Two
  Parkmore Business Park West
  Galway
  L2
  -
  Common
  01/08/2025
  9850
  792038.50
  01/24/2025
  10/10/2024
  /s/ Jennifer Ruchti, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Brett Wall