content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001696831</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001665918</issuerCik>
        <issuerName>US Foods Holding Corp.</issuerName>
        <secFileNumber>001-37786</secFileNumber>
        <issuerAddress>
          <com:street1>9399 W. HIGGINS RD.</com:street1>
          <com:street2>SUITE 100</com:street2>
          <com:city>ROSEMONT</com:city>
          <com:stateOrCountry>IL</com:stateOrCountry>
          <com:zipCode>60018</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>8477208000</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Locascio Dirk J.</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem Street</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>10000</noOfUnitsSold>
        <aggregateMarketValue>579500.00</aggregateMarketValue>
        <noOfUnitsOutstanding>244558482</noOfUnitsOutstanding>
        <approxSaleDate>09/12/2024</approxSaleDate>
        <securitiesExchangeName>NYSE</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>09/12/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Options Granted 03/23/2020</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>10000</amountOfSecuritiesAcquired>
        <paymentDate>09/12/2024</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>09/12/2024</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>06/11/2024</planAdoptionDate>
        </planAdoptionDates>
        <signature>/s/ Daniel Tucci, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Dirk Locascio</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
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text: 144
  0001696831
  XXXXXXXX
  LIVE
  0001665918
  US Foods Holding Corp.
  001-37786
  9399 W. HIGGINS RD.
  SUITE 100
  ROSEMONT
  IL
  60018
  8477208000
  Locascio Dirk J.
  Officer
  Common
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  10000
  579500.00
  244558482
  09/12/2024
  NYSE
  Common
  09/12/2024
  Options Granted 03/23/2020
  Issuer
  N
  10000
  09/12/2024
  Cash
  Y
  09/12/2024
  06/11/2024
  /s/ Daniel Tucci, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Dirk Locascio