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        <filer>
          <filerCredentials>
            <cik>0001980122</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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      <issuerInfo>
        <issuerCik>0001070081</issuerCik>
        <issuerName>PTC THERAPEUTICS, INC.</issuerName>
        <secFileNumber>001-35969</secFileNumber>
        <issuerAddress>
          <com:street1>500 WARREN CORPORATE CENTER DRIVE</com:street1>
          <com:city>WARREN</com:city>
          <com:stateOrCountry>NJ</com:stateOrCountry>
          <com:zipCode>07059</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>9082227000</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Bell William F. Jr.</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Former Director</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem Street</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>6666</noOfUnitsSold>
        <aggregateMarketValue>297103.62</aggregateMarketValue>
        <noOfUnitsOutstanding>77125143</noOfUnitsOutstanding>
        <approxSaleDate>01/10/2025</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>01/10/2025</acquiredDate>
        <natureOfAcquisitionTransaction>Option Granted 02/15/2024</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>6666</amountOfSecuritiesAcquired>
        <paymentDate>01/10/2025</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>01/10/2025</noticeDate>
        <signature>/s/ Jackson Harris, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for William F. Bell Jr.</signature>
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text: 144
  0001980122
  XXXXXXXX
  LIVE
  0001070081
  PTC THERAPEUTICS, INC.
  001-35969
  500 WARREN CORPORATE CENTER DRIVE
  WARREN
  NJ
  07059
  9082227000
  Bell William F. Jr.
  Former Director
  Common
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  6666
  297103.62
  77125143
  01/10/2025
  NASDAQ
  Common
  01/10/2025
  Option Granted 02/15/2024
  Issuer
  N
  6666
  01/10/2025
  Cash
  Y
  01/10/2025
  /s/ Jackson Harris, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for William F. Bell Jr.