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        <filer>
          <filerCredentials>
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            <ccc>XXXXXXXX</ccc>
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        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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      <issuerInfo>
        <issuerCik>0001070494</issuerCik>
        <issuerName>ACADIA PHARMACEUTICALS INC</issuerName>
        <secFileNumber>000-50768</secFileNumber>
        <issuerAddress>
          <com:street1>12830 EL CAMINO REAL</com:street1>
          <com:street2>SUITE 400</com:street2>
          <com:city>SAN DIEGO</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>92130</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>858-558-2871</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Kihara James</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>COMMON STOCK</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Piper Sandler &amp; Co.</name>
          <address>
            <com:street1>800 Nicollet Mall</com:street1>
            <com:city>Minneapolis</com:city>
            <com:stateOrCountry>MN</com:stateOrCountry>
            <com:zipCode>55414</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>2000</noOfUnitsSold>
        <aggregateMarketValue>56120.00</aggregateMarketValue>
        <noOfUnitsOutstanding>164180000</noOfUnitsOutstanding>
        <approxSaleDate>12/15/2023</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>COMMON STOCK</securitiesClassTitle>
        <acquiredDate>04/07/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Units</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Acadia Pharmaceuticals</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>2000</amountOfSecuritiesAcquired>
        <paymentDate>12/15/2023</paymentDate>
        <natureOfPayment>CASH</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>JAMES KIHARA</name>
          <address>
            <com:street1>15658 Via Montecristo</com:street1>
            <com:city>San Diego</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>92127</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Acadia Pharmaceuticals Inc</securitiesClassTitle>
        <saleDate>09/15/2023</saleDate>
        <amountOfSecuritiesSold>2000</amountOfSecuritiesSold>
        <grossProceeds>51760.00</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>12/15/2023</noticeDate>
        <signature>Alex Johnson, a duly authorized representative of Piper Sandler &amp; Co Corporate &amp; Venture Services FA, as attorney-in-fact for James Kihara</signature>
      </noticeSignature>
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text: 144
  0001816160
  XXXXXXXX
  LIVE
  0001070494
  ACADIA PHARMACEUTICALS INC
  000-50768
  12830 EL CAMINO REAL
  SUITE 400
  SAN DIEGO
  CA
  92130
  858-558-2871
  Kihara James
  Officer
  COMMON STOCK
  Piper Sandler & Co.
  800 Nicollet Mall
  Minneapolis
  MN
  55414
  2000
  56120.00
  164180000
  12/15/2023
  NASDAQ
  COMMON STOCK
  04/07/2022
  Restricted Stock Units
  Acadia Pharmaceuticals
  N
  2000
  12/15/2023
  CASH
  N
  JAMES KIHARA
  15658 Via Montecristo
  San Diego
  CA
  92127
  Acadia Pharmaceuticals Inc
  09/15/2023
  2000
  51760.00
  12/15/2023
  Alex Johnson, a duly authorized representative of Piper Sandler & Co Corporate & Venture Services FA, as attorney-in-fact for James Kihara