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        <filer>
          <filerCredentials>
            <cik>0001233171</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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      <issuerInfo>
        <issuerCik>0001645590</issuerCik>
        <issuerName>Hewlett Packard Enterprise Company</issuerName>
        <secFileNumber>001-37483</secFileNumber>
        <issuerAddress>
          <com:street1>1701 East Mossy Oaks Road</com:street1>
          <com:city>Spring</com:city>
          <com:stateOrCountry>TX</com:stateOrCountry>
          <com:zipCode>77389</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>678-259-9860</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Gary M. Reiner</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Director</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>J.P. Morgan Securities LLC</name>
          <address>
            <com:street1>390 Madison Avenue</com:street1>
            <com:street2>6th Floor</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10017</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>50000</noOfUnitsSold>
        <aggregateMarketValue>1017500</aggregateMarketValue>
        <noOfUnitsOutstanding>1299673270</noOfUnitsOutstanding>
        <approxSaleDate>06/06/2024</approxSaleDate>
        <securitiesExchangeName>NYSE</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <acquiredDate>04/04/2023</acquiredDate>
        <natureOfAcquisitionTransaction>Compensation</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>2017</amountOfSecuritiesAcquired>
        <paymentDate>04/04/2023</paymentDate>
        <natureOfPayment>NA</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <acquiredDate>04/05/2023</acquiredDate>
        <natureOfAcquisitionTransaction>Compensation</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>15118</amountOfSecuritiesAcquired>
        <paymentDate>04/05/2023</paymentDate>
        <natureOfPayment>NA</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <acquiredDate>04/16/2021</acquiredDate>
        <natureOfAcquisitionTransaction>Compensation</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>20095</amountOfSecuritiesAcquired>
        <paymentDate>04/16/2021</paymentDate>
        <natureOfPayment>NA</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <acquiredDate>05/31/2016</acquiredDate>
        <natureOfAcquisitionTransaction>Compensation</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>1556</amountOfSecuritiesAcquired>
        <paymentDate>05/31/2016</paymentDate>
        <natureOfPayment>NA</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <acquiredDate>04/20/2016</acquiredDate>
        <natureOfAcquisitionTransaction>Compensation</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>7542</amountOfSecuritiesAcquired>
        <paymentDate>04/20/2016</paymentDate>
        <natureOfPayment>NA</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <acquiredDate>04/21/2015</acquiredDate>
        <natureOfAcquisitionTransaction>Compensation</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>3672</amountOfSecuritiesAcquired>
        <paymentDate>04/21/2015</paymentDate>
        <natureOfPayment>NA</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>06/06/2024</noticeDate>
        <signature>/s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Gary M. Reiner</signature>
      </noticeSignature>
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text: 144
  0001233171
  XXXXXXXX
  LIVE
  0001645590
  Hewlett Packard Enterprise Company
  001-37483
  1701 East Mossy Oaks Road
  Spring
  TX
  77389
  678-259-9860
  Gary M. Reiner
  Director
  Common Stock
  J.P. Morgan Securities LLC
  390 Madison Avenue
  6th Floor
  New York
  NY
  10017
  50000
  1017500
  1299673270
  06/06/2024
  NYSE
  Common Stock
  04/04/2023
  Compensation
  Issuer
  N
  2017
  04/04/2023
  NA
  Common Stock
  04/05/2023
  Compensation
  Issuer
  N
  15118
  04/05/2023
  NA
  Common Stock
  04/16/2021
  Compensation
  Issuer
  N
  20095
  04/16/2021
  NA
  Common Stock
  05/31/2016
  Compensation
  Issuer
  N
  1556
  05/31/2016
  NA
  Common Stock
  04/20/2016
  Compensation
  Issuer
  N
  7542
  04/20/2016
  NA
  Common Stock
  04/21/2015
  Compensation
  Issuer
  N
  3672
  04/21/2015
  NA
  Y
  06/06/2024
  /s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Gary M. Reiner