content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
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      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001956241</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001737953</issuerCik>
        <issuerName>Replimune Group Inc.</issuerName>
        <secFileNumber>001-38596</secFileNumber>
        <issuerAddress>
          <com:street1>500 Unicorn Park Drive</com:street1>
          <com:street2>Suite 303</com:street2>
          <com:city>Woburn</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>01801</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>7812229600</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Konstantinos Xynos</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>J.P. Morgan Securities LLC</name>
          <address>
            <com:street1>390 Madison Avenue</com:street1>
            <com:street2>6th Floor</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10017</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>15881</noOfUnitsSold>
        <aggregateMarketValue>119185</aggregateMarketValue>
        <noOfUnitsOutstanding>60415105</noOfUnitsOutstanding>
        <approxSaleDate>06/07/2024</approxSaleDate>
        <securitiesExchangeName>Nasdaq</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>11/15/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Rsetricted Stock Units</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>8798</amountOfSecuritiesAcquired>
        <paymentDate>11/15/2022</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>11/15/2023</acquiredDate>
        <natureOfAcquisitionTransaction>Rsetricted Stock Units</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>7083</amountOfSecuritiesAcquired>
        <paymentDate>11/15/2023</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>06/07/2024</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>02/13/2024</planAdoptionDate>
        </planAdoptionDates>
        <signature>/s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Konstantinos Xynos</signature>
      </noticeSignature>
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text: 144
  0001956241
  XXXXXXXX
  LIVE
  0001737953
  Replimune Group Inc.
  001-38596
  500 Unicorn Park Drive
  Suite 303
  Woburn
  MA
  01801
  7812229600
  Konstantinos Xynos
  Officer
  Common
  J.P. Morgan Securities LLC
  390 Madison Avenue
  6th Floor
  New York
  NY
  10017
  15881
  119185
  60415105
  06/07/2024
  Nasdaq
  Common
  11/15/2022
  Rsetricted Stock Units
  Issuer
  N
  8798
  11/15/2022
  Compensation
  Common
  11/15/2023
  Rsetricted Stock Units
  Issuer
  N
  7083
  11/15/2023
  Compensation
  Y
  06/07/2024
  02/13/2024
  /s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Konstantinos Xynos