content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001878264</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001142417</issuerCik>
        <issuerName>NEXSTAR MEDIA GROUP, INC.</issuerName>
        <secFileNumber>000-50478</secFileNumber>
        <issuerAddress>
          <com:street1>545 EAST JOHN CARPENTER FREEWAY</com:street1>
          <com:street2>SUITE 700</com:street2>
          <com:city>IRVING</com:city>
          <com:stateOrCountry>TX</com:stateOrCountry>
          <com:zipCode>75062</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>972-373-8800</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Gliha Lee Ann</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem Street</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>757</noOfUnitsSold>
        <aggregateMarketValue>125093.95</aggregateMarketValue>
        <noOfUnitsOutstanding>30148875</noOfUnitsOutstanding>
        <approxSaleDate>06/17/2025</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>06/16/2025</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>757</amountOfSecuritiesAcquired>
        <paymentDate>06/16/2025</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Lee A. Gliha</name>
          <address>
            <com:street1>545 E. John Carpenter Freeway</com:street1>
            <com:street2>Suite 700</com:street2>
            <com:city>Irving</com:city>
            <com:stateOrCountry>TX</com:stateOrCountry>
            <com:zipCode>75062</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>05/27/2025</saleDate>
        <amountOfSecuritiesSold>1437</amountOfSecuritiesSold>
        <grossProceeds>249453.58</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Lee A. Gliha</name>
          <address>
            <com:street1>545 E. John Carpenter Freeway</com:street1>
            <com:street2>Suite 700</com:street2>
            <com:city>Irving</com:city>
            <com:stateOrCountry>TX</com:stateOrCountry>
            <com:zipCode>75062</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>06/04/2025</saleDate>
        <amountOfSecuritiesSold>526</amountOfSecuritiesSold>
        <grossProceeds>87972.66</grossProceeds>
      </securitiesSoldInPast3Months>
      <remarks>Sale includes an amount necessary to cover a tax obligation resulting from the settlement of a vested equity award distribution.</remarks>
      <noticeSignature>
        <noticeDate>06/17/2025</noticeDate>
        <signature>/s/ Bradley Camilo, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Lee A. Gliha</signature>
      </noticeSignature>
    </formData>
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text: 144
  0001878264
  XXXXXXXX
  LIVE
  0001142417
  NEXSTAR MEDIA GROUP, INC.
  000-50478
  545 EAST JOHN CARPENTER FREEWAY
  SUITE 700
  IRVING
  TX
  75062
  972-373-8800
  Gliha Lee Ann
  Officer
  Common
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  757
  125093.95
  30148875
  06/17/2025
  NASDAQ
  Common
  06/16/2025
  Restricted Stock Vesting
  Issuer
  N
  757
  06/16/2025
  Compensation
  N
  Lee A. Gliha
  545 E. John Carpenter Freeway
  Suite 700
  Irving
  TX
  75062
  Common
  05/27/2025
  1437
  249453.58
  Lee A. Gliha
  545 E. John Carpenter Freeway
  Suite 700
  Irving
  TX
  75062
  Common
  06/04/2025
  526
  87972.66
  Sale includes an amount necessary to cover a tax obligation resulting from the settlement of a vested equity award distribution.
  06/17/2025
  /s/ Bradley Camilo, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Lee A. Gliha