content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001809355</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001627475</issuerCik>
        <issuerName>UPWORK, INC</issuerName>
        <secFileNumber>001-38678</secFileNumber>
        <issuerAddress>
          <com:street1>475 BRANNAN STREET</com:street1>
          <com:street2>SUITE 430</com:street2>
          <com:city>SAN FRANCISCO</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94107</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>650-316-7500</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Gilpin Eric</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Morgan Stanley Smith Barney LLC</name>
          <address>
            <com:street1>1 New York Plaza</com:street1>
            <com:street2>38th Floor</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10004</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>62941</noOfUnitsSold>
        <aggregateMarketValue>874879.00</aggregateMarketValue>
        <noOfUnitsOutstanding>134883597</noOfUnitsOutstanding>
        <approxSaleDate>08/23/2023</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>05/14/2018</acquiredDate>
        <natureOfAcquisitionTransaction>Shares Purchased through Employee Stock Purchase Plan</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>1642</amountOfSecuritiesAcquired>
        <paymentDate>05/14/2018</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>05/14/2020</acquiredDate>
        <natureOfAcquisitionTransaction>Shares Purchased through Employee Stock Purchase Plan</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>964</amountOfSecuritiesAcquired>
        <paymentDate>05/14/2020</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>11/13/2020</acquiredDate>
        <natureOfAcquisitionTransaction>Shares Purchased through Employee Stock Purchase Plan</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>1081</amountOfSecuritiesAcquired>
        <paymentDate>11/13/2020</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>05/14/2021</acquiredDate>
        <natureOfAcquisitionTransaction>Shares Purchased through Employee Stock Purchase Plan</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>1065</amountOfSecuritiesAcquired>
        <paymentDate>05/14/2021</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>11/12/2021</acquiredDate>
        <natureOfAcquisitionTransaction>Shares Purchased through Employee Stock Purchase Plan</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>997</amountOfSecuritiesAcquired>
        <paymentDate>11/12/2021</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>05/13/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Shares Purchased through Employee Stock Purchase Plan</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>555</amountOfSecuritiesAcquired>
        <paymentDate>05/13/2022</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>11/15/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Shares Purchased through Employee Stock Purchase Plan</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>1677</amountOfSecuritiesAcquired>
        <paymentDate>11/15/2022</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>02/18/2021</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>3346</amountOfSecuritiesAcquired>
        <paymentDate>02/18/2021</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>05/18/2021</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>3945</amountOfSecuritiesAcquired>
        <paymentDate>05/18/2021</paymentDate>
        <natureOfPayment>Not Applicable</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>11/18/2021</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>2015</amountOfSecuritiesAcquired>
        <paymentDate>11/18/2021</paymentDate>
        <natureOfPayment>Not Applicable</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>02/18/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>4287</amountOfSecuritiesAcquired>
        <paymentDate>02/18/2022</paymentDate>
        <natureOfPayment>Not Applicable</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>05/18/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>5936</amountOfSecuritiesAcquired>
        <paymentDate>05/18/2022</paymentDate>
        <natureOfPayment>Not Applicable</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>08/18/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>6096</amountOfSecuritiesAcquired>
        <paymentDate>08/18/2022</paymentDate>
        <natureOfPayment>Not Applicable</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>11/18/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>7309</amountOfSecuritiesAcquired>
        <paymentDate>11/18/2022</paymentDate>
        <natureOfPayment>Not Applicable</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>02/18/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>11950</amountOfSecuritiesAcquired>
        <paymentDate>02/18/2023</paymentDate>
        <natureOfPayment>Not Applicable</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>05/18/2023</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>10076</amountOfSecuritiesAcquired>
        <paymentDate>05/18/2023</paymentDate>
        <natureOfPayment>Not Applicable</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>08/24/2023</noticeDate>
        <signature>/s/ Eric Gilpin</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 11243}]
text: 144
  0001809355
  XXXXXXXX
  LIVE
  0001627475
  UPWORK, INC
  001-38678
  475 BRANNAN STREET
  SUITE 430
  SAN FRANCISCO
  CA
  94107
  650-316-7500
  Gilpin Eric
  Officer
  Common
  Morgan Stanley Smith Barney LLC
  1 New York Plaza
  38th Floor
  New York
  NY
  10004
  62941
  874879.00
  134883597
  08/23/2023
  NASDAQ
  Common
  05/14/2018
  Shares Purchased through Employee Stock Purchase Plan
  Issuer
  N
  1642
  05/14/2018
  Cash
  Common
  05/14/2020
  Shares Purchased through Employee Stock Purchase Plan
  Issuer
  N
  964
  05/14/2020
  Cash
  Common
  11/13/2020
  Shares Purchased through Employee Stock Purchase Plan
  Issuer
  N
  1081
  11/13/2020
  Cash
  Common
  05/14/2021
  Shares Purchased through Employee Stock Purchase Plan
  Issuer
  N
  1065
  05/14/2021
  Cash
  Common
  11/12/2021
  Shares Purchased through Employee Stock Purchase Plan
  Issuer
  N
  997
  11/12/2021
  Cash
  Common
  05/13/2022
  Shares Purchased through Employee Stock Purchase Plan
  Issuer
  N
  555
  05/13/2022
  Cash
  Common
  11/15/2022
  Shares Purchased through Employee Stock Purchase Plan
  Issuer
  N
  1677
  11/15/2022
  Cash
  Common
  02/18/2021
  Restricted stock vesting under a registered plan
  Issuer
  N
  3346
  02/18/2021
  Cash
  Common
  05/18/2021
  Restricted stock vesting under a registered plan
  Issuer
  N
  3945
  05/18/2021
  Not Applicable
  Common
  11/18/2021
  Restricted stock vesting under a registered plan
  Issuer
  N
  2015
  11/18/2021
  Not Applicable
  Common
  02/18/2022
  Restricted stock vesting under a registered plan
  Issuer
  N
  4287
  02/18/2022
  Not Applicable
  Common
  05/18/2022
  Restricted stock vesting under a registered plan
  Issuer
  N
  5936
  05/18/2022
  Not Applicable
  Common
  08/18/2022
  Restricted stock vesting under a registered plan
  Issuer
  N
  6096
  08/18/2022
  Not Applicable
  Common
  11/18/2022
  Restricted stock vesting under a registered plan
  Issuer
  N
  7309
  11/18/2022
  Not Applicable
  Common
  02/18/2022
  Restricted stock vesting under a registered plan
  Issuer
  N
  11950
  02/18/2023
  Not Applicable
  Common
  05/18/2023
  Restricted stock vesting under a registered plan
  Issuer
  N
  10076
  05/18/2023
  Not Applicable
  Y
  08/24/2023
  /s/ Eric Gilpin