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        <filer>
          <filerCredentials>
            <cik>0001980122</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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      <issuerInfo>
        <issuerCik>0001070081</issuerCik>
        <issuerName>PTC THERAPEUTICS, INC.</issuerName>
        <secFileNumber>001-35969</secFileNumber>
        <issuerAddress>
          <com:street1>500 WARREN CORPORATE CENTER DRIVE</com:street1>
          <com:city>WARREN</com:city>
          <com:stateOrCountry>NJ</com:stateOrCountry>
          <com:zipCode>07059</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>9082227000</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Bell William F. Jr.</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Former Director</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem Street</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>10556</noOfUnitsSold>
        <aggregateMarketValue>527800.00</aggregateMarketValue>
        <noOfUnitsOutstanding>77125143</noOfUnitsOutstanding>
        <approxSaleDate>02/03/2025</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>02/03/2025</acquiredDate>
        <natureOfAcquisitionTransaction>Option Granted- 06/06/2023</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>10556</amountOfSecuritiesAcquired>
        <paymentDate>02/03/2025</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>William F. Bell</name>
          <address>
            <com:street1>500 Warren Corporate Center Drive</com:street1>
            <com:city>Warren</com:city>
            <com:stateOrCountry>NJ</com:stateOrCountry>
            <com:zipCode>07059</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>01/10/2025</saleDate>
        <amountOfSecuritiesSold>6666</amountOfSecuritiesSold>
        <grossProceeds>297103.62</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>02/03/2025</noticeDate>
        <signature>/s/ Eric Janiak, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for William F. Bell</signature>
      </noticeSignature>
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text: 144
  0001980122
  XXXXXXXX
  LIVE
  0001070081
  PTC THERAPEUTICS, INC.
  001-35969
  500 WARREN CORPORATE CENTER DRIVE
  WARREN
  NJ
  07059
  9082227000
  Bell William F. Jr.
  Former Director
  Common
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  10556
  527800.00
  77125143
  02/03/2025
  NASDAQ
  Common
  02/03/2025
  Option Granted- 06/06/2023
  Issuer
  N
  10556
  02/03/2025
  Cash
  N
  William F. Bell
  500 Warren Corporate Center Drive
  Warren
  NJ
  07059
  Common
  01/10/2025
  6666
  297103.62
  02/03/2025
  /s/ Eric Janiak, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for William F. Bell