content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001174454</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001585364</issuerCik>
        <issuerName>PERRIGO Co plc</issuerName>
        <secFileNumber>001-36353</secFileNumber>
        <issuerAddress>
          <com:street1>THE SHARP BUILDING</com:street1>
          <com:street2>HOGAN PLACE</com:street2>
          <com:city>DUBLIN 2</com:city>
          <com:stateOrCountry>L2</com:stateOrCountry>
          <com:zipCode>D02 TY74</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>269-673-8451</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>KINDLER JEFFREY B</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Director</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem Street</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>17598</noOfUnitsSold>
        <aggregateMarketValue>497425.93</aggregateMarketValue>
        <noOfUnitsOutstanding>136427804</noOfUnitsOutstanding>
        <approxSaleDate>12/09/2024</approxSaleDate>
        <securitiesExchangeName>NYSE</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>07/20/2017</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>528</amountOfSecuritiesAcquired>
        <paymentDate>07/20/2017</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>06/06/2018</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>2217</amountOfSecuritiesAcquired>
        <paymentDate>06/06/2018</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>05/15/2019</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>2064</amountOfSecuritiesAcquired>
        <paymentDate>05/15/2019</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>05/15/2020</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>3148</amountOfSecuritiesAcquired>
        <paymentDate>05/15/2020</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>05/07/2021</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>3018</amountOfSecuritiesAcquired>
        <paymentDate>05/07/2021</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>05/17/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>3431</amountOfSecuritiesAcquired>
        <paymentDate>05/17/2022</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>05/17/2023</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>3192</amountOfSecuritiesAcquired>
        <paymentDate>05/17/2023</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>12/09/2024</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>09/09/2024</planAdoptionDate>
        </planAdoptionDates>
        <signature>/s/ Andrew Glade, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Jeffrey B. Kindler</signature>
      </noticeSignature>
    </formData>
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text: 144
  0001174454
  XXXXXXXX
  LIVE
  0001585364
  PERRIGO Co plc
  001-36353
  THE SHARP BUILDING
  HOGAN PLACE
  DUBLIN 2
  L2
  D02 TY74
  269-673-8451
  KINDLER JEFFREY B
  Director
  Common
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  17598
  497425.93
  136427804
  12/09/2024
  NYSE
  Common
  07/20/2017
  Restricted Stock Vesting
  Issuer
  N
  528
  07/20/2017
  Compensation
  Common
  06/06/2018
  Restricted Stock Vesting
  Issuer
  N
  2217
  06/06/2018
  Compensation
  Common
  05/15/2019
  Restricted Stock Vesting
  Issuer
  N
  2064
  05/15/2019
  Compensation
  Common
  05/15/2020
  Restricted Stock Vesting
  Issuer
  N
  3148
  05/15/2020
  Compensation
  Common
  05/07/2021
  Restricted Stock Vesting
  Issuer
  N
  3018
  05/07/2021
  Compensation
  Common
  05/17/2022
  Restricted Stock Vesting
  Issuer
  N
  3431
  05/17/2022
  Compensation
  Common
  05/17/2023
  Restricted Stock Vesting
  Issuer
  N
  3192
  05/17/2023
  Compensation
  Y
  12/09/2024
  09/09/2024
  /s/ Andrew Glade, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Jeffrey B. Kindler