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      <submissionType>144</submissionType>
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        <filer>
          <filerCredentials>
            <cik>0001567878</cik>
            <ccc>XXXXXXXX</ccc>
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        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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      <issuerInfo>
        <issuerCik>0001555280</issuerCik>
        <issuerName>Zoetis Inc.</issuerName>
        <secFileNumber>001-35797</secFileNumber>
        <issuerAddress>
          <com:street1>10 SYLVAN WAY</com:street1>
          <com:city>PARSIPPANY</com:city>
          <com:stateOrCountry>NJ</com:stateOrCountry>
          <com:zipCode>07054</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>973-822-7000</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Lagano Roxanne</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Merrill Lynch</name>
          <address>
            <com:street1>225 Liberty St</com:street1>
            <com:street2>Floor 37</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10281</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>923</noOfUnitsSold>
        <aggregateMarketValue>176689.89</aggregateMarketValue>
        <noOfUnitsOutstanding>459113691</noOfUnitsOutstanding>
        <approxSaleDate>01/18/2024</approxSaleDate>
        <securitiesExchangeName>NYSE</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <acquiredDate>02/13/2021</acquiredDate>
        <natureOfAcquisitionTransaction>Vesting of restricted stock unit award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Zoetis Inc.</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>923</amountOfSecuritiesAcquired>
        <paymentDate>02/13/2021</paymentDate>
        <natureOfPayment>Granted as part of issuer equity compensation plan</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Roxanne Lagano</name>
          <address>
            <com:street1>10 SYLVAN WAY</com:street1>
            <com:city>PARSIPPANY</com:city>
            <com:stateOrCountry>NJ</com:stateOrCountry>
            <com:zipCode>07054</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <saleDate>10/18/2023</saleDate>
        <amountOfSecuritiesSold>923</amountOfSecuritiesSold>
        <grossProceeds>159605.16</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Roxanne Lagano</name>
          <address>
            <com:street1>10 SYLVAN WAY</com:street1>
            <com:city>PARSIPPANY</com:city>
            <com:stateOrCountry>NJ</com:stateOrCountry>
            <com:zipCode>07054</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <saleDate>11/17/2023</saleDate>
        <amountOfSecuritiesSold>923</amountOfSecuritiesSold>
        <grossProceeds>163795.58</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Roxanne Lagano</name>
          <address>
            <com:street1>10 SYLVAN WAY</com:street1>
            <com:city>PARSIPPANY</com:city>
            <com:stateOrCountry>NJ</com:stateOrCountry>
            <com:zipCode>07054</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <saleDate>12/14/2023</saleDate>
        <amountOfSecuritiesSold>2500</amountOfSecuritiesSold>
        <grossProceeds>500000.00</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Roxanne Lagano</name>
          <address>
            <com:street1>10 SYLVAN WAY</com:street1>
            <com:city>PARSIPPANY</com:city>
            <com:stateOrCountry>NJ</com:stateOrCountry>
            <com:zipCode>07054</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <saleDate>12/18/2023</saleDate>
        <amountOfSecuritiesSold>923</amountOfSecuritiesSold>
        <grossProceeds>182883.22</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>01/18/2024</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>06/01/2023</planAdoptionDate>
        </planAdoptionDates>
        <signature>Roxanne Lagano</signature>
      </noticeSignature>
    </formData>
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text: 144
  0001567878
  XXXXXXXX
  LIVE
  0001555280
  Zoetis Inc.
  001-35797
  10 SYLVAN WAY
  PARSIPPANY
  NJ
  07054
  973-822-7000
  Lagano Roxanne
  Officer
  Common Stock
  Merrill Lynch
  225 Liberty St
  Floor 37
  New York
  NY
  10281
  923
  176689.89
  459113691
  01/18/2024
  NYSE
  Common Stock
  02/13/2021
  Vesting of restricted stock unit award
  Zoetis Inc.
  N
  923
  02/13/2021
  Granted as part of issuer equity compensation plan
  N
  Roxanne Lagano
  10 SYLVAN WAY
  PARSIPPANY
  NJ
  07054
  Common Stock
  10/18/2023
  923
  159605.16
  Roxanne Lagano
  10 SYLVAN WAY
  PARSIPPANY
  NJ
  07054
  Common Stock
  11/17/2023
  923
  163795.58
  Roxanne Lagano
  10 SYLVAN WAY
  PARSIPPANY
  NJ
  07054
  Common Stock
  12/14/2023
  2500
  500000.00
  Roxanne Lagano
  10 SYLVAN WAY
  PARSIPPANY
  NJ
  07054
  Common Stock
  12/18/2023
  923
  182883.22
  01/18/2024
  06/01/2023
  Roxanne Lagano