content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
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      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001665177</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
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      <issuerInfo>
        <issuerCik>0001423689</issuerCik>
        <issuerName>AGNC Investment Corp.</issuerName>
        <secFileNumber>001-34057</secFileNumber>
        <issuerAddress>
          <com:street1>7373 WISCONSIN AVENUE, 22ND FLOOR</com:street1>
          <com:city>BETHESDA</com:city>
          <com:stateOrCountry>MD</com:stateOrCountry>
          <com:zipCode>20814</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>301 968 9300</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Bell Bernice</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem Street</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>10000</noOfUnitsSold>
        <aggregateMarketValue>98500.00</aggregateMarketValue>
        <noOfUnitsOutstanding>671105859</noOfUnitsOutstanding>
        <approxSaleDate>01/26/2024</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>03/15/2023</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>10000</amountOfSecuritiesAcquired>
        <paymentDate>03/15/2023</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Bernice E. Bell</name>
          <address>
            <com:street1>7373 Wisconsin Avenue</com:street1>
            <com:street2>22nd Floor</com:street2>
            <com:city>Bethesda</com:city>
            <com:stateOrCountry>MD</com:stateOrCountry>
            <com:zipCode>20814</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>11/08/2023</saleDate>
        <amountOfSecuritiesSold>6000</amountOfSecuritiesSold>
        <grossProceeds>50665.58</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>01/26/2024</noticeDate>
        <signature>/s/ Courtney Broxterman, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Bernice E. Bell</signature>
      </noticeSignature>
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text: 144
  0001665177
  XXXXXXXX
  LIVE
  0001423689
  AGNC Investment Corp.
  001-34057
  7373 WISCONSIN AVENUE, 22ND FLOOR
  BETHESDA
  MD
  20814
  301 968 9300
  Bell Bernice
  Officer
  Common
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  10000
  98500.00
  671105859
  01/26/2024
  NASDAQ
  Common
  03/15/2023
  Restricted Stock Vesting
  Issuer
  N
  10000
  03/15/2023
  Compensation
  N
  Bernice E. Bell
  7373 Wisconsin Avenue
  22nd Floor
  Bethesda
  MD
  20814
  Common
  11/08/2023
  6000
  50665.58
  01/26/2024
  /s/ Courtney Broxterman, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Bernice E. Bell