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      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001662392</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001358762</issuerCik>
        <issuerName>REATA PHARMACEUTICALS INC</issuerName>
        <secFileNumber>001-37785</secFileNumber>
        <issuerAddress>
          <com:street1>5320 LEGACY DRIVE</com:street1>
          <com:city>PLANO</com:city>
          <com:stateOrCountry>TX</com:stateOrCountry>
          <com:zipCode>75024</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>972-865-2219</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Meyer Colin John</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Merrill Lynch</name>
          <address>
            <com:street1>225 Liberty St</com:street1>
            <com:street2>Floor 37</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10281</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>2144</noOfUnitsSold>
        <aggregateMarketValue>362483.26</aggregateMarketValue>
        <noOfUnitsOutstanding>33499825</noOfUnitsOutstanding>
        <approxSaleDate>08/15/2023</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <acquiredDate>06/30/2023</acquiredDate>
        <natureOfAcquisitionTransaction>Vesting of restricted stock unit award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>REATA PHARMACEUTICALS INC</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>1756</amountOfSecuritiesAcquired>
        <paymentDate>06/30/2023</paymentDate>
        <natureOfPayment>Granted as part of issuer equity compensation plan</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <acquiredDate>07/06/2023</acquiredDate>
        <natureOfAcquisitionTransaction>Vesting of restricted stock unit award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>REATA PHARMACEUTICALS INC</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>388</amountOfSecuritiesAcquired>
        <paymentDate>07/06/2023</paymentDate>
        <natureOfPayment>Granted as part of issuer equity compensation plan</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Colin Meyer</name>
          <address>
            <com:street1>5320 LEGACY DRIVE</com:street1>
            <com:city>PLANO</com:city>
            <com:stateOrCountry>TX</com:stateOrCountry>
            <com:zipCode>75024</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <saleDate>05/16/2023</saleDate>
        <amountOfSecuritiesSold>625</amountOfSecuritiesSold>
        <grossProceeds>50590.00</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Colin Meyer</name>
          <address>
            <com:street1>5320 LEGACY DRIVE</com:street1>
            <com:city>PLANO</com:city>
            <com:stateOrCountry>TX</com:stateOrCountry>
            <com:zipCode>75024</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <saleDate>05/15/2023</saleDate>
        <amountOfSecuritiesSold>5608</amountOfSecuritiesSold>
        <grossProceeds>476473.22</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>08/15/2023</noticeDate>
        <signature>Colin Meyer</signature>
      </noticeSignature>
    </formData>
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text: 144
  0001662392
  XXXXXXXX
  LIVE
  0001358762
  REATA PHARMACEUTICALS INC
  001-37785
  5320 LEGACY DRIVE
  PLANO
  TX
  75024
  972-865-2219
  Meyer Colin John
  Officer
  Class A Common Stock
  Merrill Lynch
  225 Liberty St
  Floor 37
  New York
  NY
  10281
  2144
  362483.26
  33499825
  08/15/2023
  NASDAQ
  Class A Common Stock
  06/30/2023
  Vesting of restricted stock unit award
  REATA PHARMACEUTICALS INC
  N
  1756
  06/30/2023
  Granted as part of issuer equity compensation plan
  Class A Common Stock
  07/06/2023
  Vesting of restricted stock unit award
  REATA PHARMACEUTICALS INC
  N
  388
  07/06/2023
  Granted as part of issuer equity compensation plan
  N
  Colin Meyer
  5320 LEGACY DRIVE
  PLANO
  TX
  75024
  Class A Common Stock
  05/16/2023
  625
  50590.00
  Colin Meyer
  5320 LEGACY DRIVE
  PLANO
  TX
  75024
  Class A Common Stock
  05/15/2023
  5608
  476473.22
  08/15/2023
  Colin Meyer