content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001656207</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001645590</issuerCik>
        <issuerName>Hewlett Packard Enterprise Co</issuerName>
        <secFileNumber>001-37483</secFileNumber>
        <issuerAddress>
          <com:street1>1701 E MOSSY OAKS ROAD</com:street1>
          <com:city>SPRING</com:city>
          <com:stateOrCountry>TX</com:stateOrCountry>
          <com:zipCode>77389</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>678-259-9860</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>MAY ALAN RICHARD</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Former Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Merrill Lynch</name>
          <address>
            <com:street1>3455 Peachtree Rd NE</com:street1>
            <com:street2>Ste 1000</com:street2>
            <com:city>Atlanta</com:city>
            <com:stateOrCountry>GA</com:stateOrCountry>
            <com:zipCode>30326</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>91286</noOfUnitsSold>
        <aggregateMarketValue>1642023.63</aggregateMarketValue>
        <noOfUnitsOutstanding>1300000000</noOfUnitsOutstanding>
        <approxSaleDate>03/05/2024</approxSaleDate>
        <securitiesExchangeName>NYSE</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>03/05/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Exercise of a Stock Award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>HEWLETT PACKARD ENTERPRISE COMPANY</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>91286</amountOfSecuritiesAcquired>
        <paymentDate>03/05/2024</paymentDate>
        <natureOfPayment>Compensatory Payment</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>03/05/2024</noticeDate>
        <signature>ALAN RICHARD MAY</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 2807}]
text: 144
  0001656207
  XXXXXXXX
  LIVE
  0001645590
  Hewlett Packard Enterprise Co
  001-37483
  1701 E MOSSY OAKS ROAD
  SPRING
  TX
  77389
  678-259-9860
  MAY ALAN RICHARD
  Former Officer
  Common
  Merrill Lynch
  3455 Peachtree Rd NE
  Ste 1000
  Atlanta
  GA
  30326
  91286
  1642023.63
  1300000000
  03/05/2024
  NYSE
  Common
  03/05/2024
  Exercise of a Stock Award
  HEWLETT PACKARD ENTERPRISE COMPANY
  N
  91286
  03/05/2024
  Compensatory Payment
  Y
  03/05/2024
  ALAN RICHARD MAY