content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001365619</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001070494</issuerCik>
        <issuerName>ACADIA PHARMACEUTICALS INC</issuerName>
        <secFileNumber>000-50768</secFileNumber>
        <issuerAddress>
          <com:street1>3611 VALLEY CENTRE DRIVE</com:street1>
          <com:street2>SUITE 300</com:street2>
          <com:city>SAN DIEGO</com:city>
          <com:stateOrCountry>MN</com:stateOrCountry>
          <com:zipCode>92130</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>858-558-2871</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Brege Laura</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Director</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Piper Sandler &amp; Co.</name>
          <address>
            <com:street1>800 Nicollet Mall, Ste 900</com:street1>
            <com:city>Minneapolis</com:city>
            <com:stateOrCountry>MN</com:stateOrCountry>
            <com:zipCode>55402</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>4500</noOfUnitsSold>
        <aggregateMarketValue>112240.00</aggregateMarketValue>
        <noOfUnitsOutstanding>162630000</noOfUnitsOutstanding>
        <approxSaleDate>06/12/2023</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>06/01/2023</acquiredDate>
        <natureOfAcquisitionTransaction>Vested RSU shares</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>4500</amountOfSecuritiesAcquired>
        <paymentDate>06/01/2023</paymentDate>
        <natureOfPayment>Equity award</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>06/12/2023</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>11/14/2022</planAdoptionDate>
        </planAdoptionDates>
        <signature>/s/ Linda Moran, as a duly authorized representative of Piper Sandler &amp; Co Corporate &amp; Venture Services FA, as attorney-in-fact for Laura Brege</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 3015}]
text: 144
  0001365619
  XXXXXXXX
  LIVE
  0001070494
  ACADIA PHARMACEUTICALS INC
  000-50768
  3611 VALLEY CENTRE DRIVE
  SUITE 300
  SAN DIEGO
  MN
  92130
  858-558-2871
  Brege Laura
  Director
  common
  Piper Sandler & Co.
  800 Nicollet Mall, Ste 900
  Minneapolis
  MN
  55402
  4500
  112240.00
  162630000
  06/12/2023
  NASDAQ
  Common
  06/01/2023
  Vested RSU shares
  Issuer
  N
  4500
  06/01/2023
  Equity award
  Y
  06/12/2023
  11/14/2022
  /s/ Linda Moran, as a duly authorized representative of Piper Sandler & Co Corporate & Venture Services FA, as attorney-in-fact for Laura Brege