content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0002070012</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001114448</issuerCik>
        <issuerName>NOVARTIS AG</issuerName>
        <secFileNumber>001-15024</secFileNumber>
        <issuerAddress>
          <com:street1>LICHTSTRASSE 35</com:street1>
          <com:city>BASEL</com:city>
          <com:stateOrCountry>V8</com:stateOrCountry>
          <com:zipCode>CH 4056</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>01141613241111</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Marshall Fiona</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>American Depository Shares</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Fidelity Brokerage Services LLC</name>
          <address>
            <com:street1>900 Salem Street</com:street1>
            <com:city>Smithfield</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02917</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>15000</noOfUnitsSold>
        <aggregateMarketValue>1690180.59</aggregateMarketValue>
        <noOfUnitsOutstanding>1975089248</noOfUnitsOutstanding>
        <approxSaleDate>05/23/2025</approxSaleDate>
        <securitiesExchangeName>NYSE</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>American Depository Shares</securitiesClassTitle>
        <acquiredDate>03/31/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>1831</amountOfSecuritiesAcquired>
        <paymentDate>03/31/2024</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>American Depository Shares</securitiesClassTitle>
        <acquiredDate>05/01/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>2613</amountOfSecuritiesAcquired>
        <paymentDate>05/01/2024</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>American Depository Shares</securitiesClassTitle>
        <acquiredDate>03/31/2025</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>4924</amountOfSecuritiesAcquired>
        <paymentDate>03/31/2025</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>American Depository Shares</securitiesClassTitle>
        <acquiredDate>05/01/2025</acquiredDate>
        <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>5632</amountOfSecuritiesAcquired>
        <paymentDate>05/01/2025</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>05/23/2025</noticeDate>
        <signature>/s/ Ryan Riviere, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Fiona Marshall</signature>
      </noticeSignature>
    </formData>
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text: 144
  0002070012
  XXXXXXXX
  LIVE
  0001114448
  NOVARTIS AG
  001-15024
  LICHTSTRASSE 35
  BASEL
  V8
  CH 4056
  01141613241111
  Marshall Fiona
  Officer
  American Depository Shares
  Fidelity Brokerage Services LLC
  900 Salem Street
  Smithfield
  RI
  02917
  15000
  1690180.59
  1975089248
  05/23/2025
  NYSE
  American Depository Shares
  03/31/2024
  Restricted Stock Vesting
  Issuer
  N
  1831
  03/31/2024
  Compensation
  American Depository Shares
  05/01/2024
  Restricted Stock Vesting
  Issuer
  N
  2613
  05/01/2024
  Compensation
  American Depository Shares
  03/31/2025
  Restricted Stock Vesting
  Issuer
  N
  4924
  03/31/2025
  Compensation
  American Depository Shares
  05/01/2025
  Restricted Stock Vesting
  Issuer
  N
  5632
  05/01/2025
  Compensation
  Y
  05/23/2025
  /s/ Ryan Riviere, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Fiona Marshall