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      <submissionType>144</submissionType>
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        <filer>
          <filerCredentials>
            <cik>0001918894</cik>
            <ccc>XXXXXXXX</ccc>
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        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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      <issuerInfo>
        <issuerCik>0001571949</issuerCik>
        <issuerName>Intercontinental Exchange, Inc.</issuerName>
        <secFileNumber>001-36198</secFileNumber>
        <issuerAddress>
          <com:street1>5660 NEW NORTHSIDE DRIVE,</com:street1>
          <com:street2>THIRD FLOOR</com:street2>
          <com:city>ATLANTA</com:city>
          <com:stateOrCountry>GA</com:stateOrCountry>
          <com:zipCode>30328</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>770-857-4700</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Foley Douglas</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Director</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Truist Investment Services Inc</name>
          <address>
            <com:street1>303 Peachtree Center Ave</com:street1>
            <com:city>Atlanta</com:city>
            <com:stateOrCountry>GA</com:stateOrCountry>
            <com:zipCode>30303</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>4800</noOfUnitsSold>
        <aggregateMarketValue>864000.00</aggregateMarketValue>
        <noOfUnitsOutstanding>573630000</noOfUnitsOutstanding>
        <approxSaleDate>06/12/2025</approxSaleDate>
        <securitiesExchangeName>NYSE</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>02/14/2024</acquiredDate>
        <natureOfAcquisitionTransaction>Stock Award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>2798</amountOfSecuritiesAcquired>
        <paymentDate>02/14/2024</paymentDate>
        <natureOfPayment>N/A</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>02/04/2025</acquiredDate>
        <natureOfAcquisitionTransaction>Stock Award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>1891</amountOfSecuritiesAcquired>
        <paymentDate>02/04/2025</paymentDate>
        <natureOfPayment>N/A</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>02/12/2025</acquiredDate>
        <natureOfAcquisitionTransaction>Stock Award</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>111</amountOfSecuritiesAcquired>
        <paymentDate>02/12/2025</paymentDate>
        <natureOfPayment>N/A</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Douglas A Foley</name>
          <address>
            <com:street1>5660 New Northside dr 3rd floor</com:street1>
            <com:city>Atlanta</com:city>
            <com:stateOrCountry>GA</com:stateOrCountry>
            <com:zipCode>30328</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>ICE</securitiesClassTitle>
        <saleDate>03/12/2025</saleDate>
        <amountOfSecuritiesSold>1600</amountOfSecuritiesSold>
        <grossProceeds>267595.81</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Douglas A Foley</name>
          <address>
            <com:street1>5660 New Northside dr 3rd floor</com:street1>
            <com:city>Atlanta</com:city>
            <com:stateOrCountry>GA</com:stateOrCountry>
            <com:zipCode>30328</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>ICE</securitiesClassTitle>
        <saleDate>05/30/2025</saleDate>
        <amountOfSecuritiesSold>8259</amountOfSecuritiesSold>
        <grossProceeds>1011231.96</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>06/12/2025</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>11/22/2024</planAdoptionDate>
        </planAdoptionDates>
        <signature>Carmen Zamores as a duly authorized representative of National Financial Services LLC, as attorney-in-fact for Douglas Foley</signature>
      </noticeSignature>
    </formData>
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text: 144
  0001918894
  XXXXXXXX
  LIVE
  0001571949
  Intercontinental Exchange, Inc.
  001-36198
  5660 NEW NORTHSIDE DRIVE,
  THIRD FLOOR
  ATLANTA
  GA
  30328
  770-857-4700
  Foley Douglas
  Director
  Common
  Truist Investment Services Inc
  303 Peachtree Center Ave
  Atlanta
  GA
  30303
  4800
  864000.00
  573630000
  06/12/2025
  NYSE
  Common
  02/14/2024
  Stock Award
  Issuer
  N
  2798
  02/14/2024
  N/A
  Common
  02/04/2025
  Stock Award
  Issuer
  N
  1891
  02/04/2025
  N/A
  Common
  02/12/2025
  Stock Award
  Issuer
  N
  111
  02/12/2025
  N/A
  N
  Douglas A Foley
  5660 New Northside dr 3rd floor
  Atlanta
  GA
  30328
  ICE
  03/12/2025
  1600
  267595.81
  Douglas A Foley
  5660 New Northside dr 3rd floor
  Atlanta
  GA
  30328
  ICE
  05/30/2025
  8259
  1011231.96
  06/12/2025
  11/22/2024
  Carmen Zamores as a duly authorized representative of National Financial Services LLC, as attorney-in-fact for Douglas Foley