content: <HTML>
  <HEAD>
       <TITLE></TITLE>
  </HEAD>
  <BODY STYLE="font: 10pt Times New Roman, Times, Serif">
  
  <P STYLE="margin: 0">&nbsp;</P>
  
  
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; width: 100%; border-collapse: collapse">
  <TR>
      <TD COLSPAN="7" STYLE="vertical-align: bottom; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>UNITED STATES</B></FONT></TD>
      <TD COLSPAN="3" STYLE="vertical-align: top; border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-bottom: black 1pt solid; border-left: black 1.5pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">OMB APPROVAL</FONT></TD></TR>
  <TR>
      <TD COLSPAN="7" STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>SECURITIES AND EXCHANGE COMMISSION</B></FONT></TD>
      <TD STYLE="vertical-align: top; border-left: black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;OMB Number:</FONT></TD>
      <TD COLSPAN="2" STYLE="vertical-align: top; border-right: black 1.5pt solid; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">3235-0101</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD COLSPAN="7" STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>Washington, D.C. 20549</B></FONT></TD>
      <TD STYLE="border-left: black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;Expires:</FONT></TD>
      <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">June 30, 2020 </FONT></TD></TR>
  <TR>
      <TD COLSPAN="7" STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD COLSPAN="3" STYLE="vertical-align: bottom; border-right: black 1.5pt solid; border-left: black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;Estimated average burden</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD COLSPAN="7" STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 14pt"><B>FORM 144</B></FONT></TD>
      <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; border-left: black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;hours per response</FONT></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">1.00 </FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD COLSPAN="7" STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>NOTICE OF PROPOSED SALE OF SECURITIES</B></FONT></TD>
      <TD COLSPAN="3" STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; border-bottom: black 1pt solid; background-color: white; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><B>SEC USE ONLY</B></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD COLSPAN="7" STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933</B></FONT></TD>
      <TD COLSPAN="3" STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; background-color: gainsboro"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;DOCUMENT SEQUENCE NO.</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD COLSPAN="7"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD COLSPAN="3" STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; border-bottom: black 1pt solid; background-color: gainsboro"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD COLSPAN="7"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD COLSPAN="3" STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; background-color: gainsboro"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;CUSIP NUMBER</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD COLSPAN="7" STYLE="border-bottom: black 1pt solid">
          <P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0 0 0 76.5pt; text-indent: -76.5pt"><B>ATTENTION:&#9;</B><FONT STYLE="font-size: 10pt"><I>Transmit
          for filing 3 copies of this form concurrently with either placing an order with a broker to execute sale or executing a sale directly
          with a market maker.</I></FONT></P>
          <P STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; margin: 0 0 0 63pt; text-indent: -63pt">&nbsp;</P></TD>
      <TD STYLE="border-bottom: black 1pt solid; border-left: black 1.5pt solid; background-color: gainsboro"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; border-bottom: black 1pt solid; background-color: gainsboro"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD COLSPAN="4" STYLE="border-left: black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;1 <I>(a)</I> NAME OF ISSUER <I>(Please type or print)</I></FONT></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding-left: 9pt; text-indent: -9pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><I>&nbsp;(b)</I> IRS IDENT. NO.</FONT></TD>
      <TD COLSPAN="2" STYLE="padding-left: 9pt; text-indent: -9pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><I>&nbsp;(c)</I> S.E.C. FILE NO.</FONT></TD>
      <TD COLSPAN="3" STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; background-color: gainsboro"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;WORK LOCATION</FONT></TD></TR>
  <TR STYLE="vertical-align: bottom">
      <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; border-left: black 1.5pt solid">
          <P STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; margin: 0">&nbsp;</P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">Alector, Inc. </P></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; border-bottom: black 1pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;462702363</FONT></TD>
      <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;001-38792</FONT></TD>
      <TD COLSPAN="3" STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; border-bottom: black 1pt solid; background-color: gainsboro"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-left: black 1.5pt solid; padding-left: 27pt; text-indent: -27pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;1 <I>(d)</I> ADDRESS OF ISSUER</FONT></TD>
      <TD COLSPAN="3"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;STREET </FONT></TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">CITY</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">STATE</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">ZIP CODE</FONT></TD>
      <TD COLSPAN="3" STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; border-bottom: black 1pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><I>&nbsp;(e)</I> TELEPHONE NO</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-left: black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD COLSPAN="3"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">AREA CODE</FONT></TD>
      <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">NUMBER</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: black 1pt solid; border-left: black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;131 Oyster Point Blvd, Suite 600</FONT></TD>
      <TD COLSPAN="3" STYLE="border-bottom: black 1pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp; </FONT></TD>
      <TD STYLE="border-bottom: black 1pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;South San Francisco </FONT></TD>
      <TD STYLE="border-bottom: black 1pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;CA</FONT></TD>
      <TD STYLE="border-bottom: black 1pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"> 94080</FONT></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; border-bottom: black 1pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">415</FONT></TD>
      <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; border-bottom: black 1pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;231-5660</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;2 <I>(a)</I> NAME OF PERSON FOR WHOSE ACCOUNT THE SECURITIES ARE TO BE SOLD</FONT></TD>
      <TD STYLE="border-right: black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="border-right: black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><I>&nbsp;(b) </I>RELATIONSHIP TO ISSUER</FONT></TD>
      <TD COLSPAN="2"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><I>(c) </I>ADDRESS STREET </FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">CITY</FONT></TD>
      <TD STYLE="padding-left: 0.25in; text-indent: -0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">STATE</FONT></TD>
      <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">ZIP CODE</FONT></TD></TR>
  <TR STYLE="vertical-align: bottom">
      <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; border-bottom: black 1pt solid">
          <P STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; margin: 0">&nbsp;</P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">OrbiMed Advisors LLC on behalf of OrbiMed Private Investments IV - AL (Feeder), LP</P></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Shareholder</FONT></TD>
      <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;c/o OrbiMed Advisors LLC<BR>
  
  601 Lexington Avenue, 54th Floor
  </FONT></TD>
      <TD STYLE="border-bottom: black 1pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">New York         </FONT></TD>
      <TD STYLE="border-bottom: black 1pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">NY</FONT></TD>
      <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; border-bottom: black 1pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">10022</FONT></TD></TR>
  <TR>
      <TD STYLE="width: 26%">&nbsp;</TD>
      <TD STYLE="width: 1%">&nbsp;</TD>
      <TD STYLE="width: 5%">&nbsp;</TD>
      <TD STYLE="width: 14%">&nbsp;</TD>
      <TD STYLE="width: 16%">&nbsp;</TD>
      <TD STYLE="width: 9%">&nbsp;</TD>
      <TD STYLE="width: 10%">&nbsp;</TD>
      <TD STYLE="width: 9%">&nbsp;</TD>
      <TD STYLE="width: 3%">&nbsp;</TD>
      <TD STYLE="width: 7%">&nbsp;</TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><I>INSTRUCTION: The person filing this notice
  should contact the issuer to obtain the I.R.S. Identification Number and the S.E.C. File Number.</I></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 11%; border-top: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">3 (<I>a)</I></FONT></TD>
      <TD STYLE="width: 23%; border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><I>(b)</I></FONT></TD>
      <TD STYLE="width: 10%; border-top: black 1.5pt solid; border-bottom: black 1pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><B>SEC USE ONLY</B></FONT></TD>
      <TD STYLE="width: 10%; border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><I>&nbsp;(c)</I></FONT></TD>
      <TD STYLE="width: 11%; border-top: black 1.5pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><I>&nbsp;(d)</I></FONT></TD>
      <TD STYLE="width: 12%; border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><I>&nbsp;(e)</I></FONT></TD>
      <TD STYLE="width: 12%; border-top: black 1.5pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><I>&nbsp;(f)</I></FONT></TD>
      <TD STYLE="width: 11%; border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><I>&nbsp;(g)</I></FONT></TD></TR>
  <TR>
      <TD STYLE="vertical-align: bottom; border-left: black 1.5pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><B>Title of the Class of Securities To Be Sold</B></FONT></TD>
      <TD STYLE="vertical-align: bottom; border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><B>Name and Address of Each Broker Through Whom the Securities are to be Offered or Each Market Maker who is Acquiring the Securities</B></FONT></TD>
      <TD STYLE="vertical-align: bottom; padding: 1.5pt; background-color: gainsboro">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center; background-color: gainsboro"><B>Broker-Dealer
          </B></P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center; background-color: gainsboro"><B>File Number</B></P></TD>
      <TD STYLE="vertical-align: top; border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><B>Number of Shares or Other Units To Be Sold</B></FONT></TD>
      <TD STYLE="vertical-align: top; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><B>Aggregate Market Value</B></FONT></TD>
      <TD STYLE="text-align: center; vertical-align: top; border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><B>Number of Shares or Other Units Outstanding</B></FONT></TD>
      <TD STYLE="text-align: center; vertical-align: top; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><B>Approximate Date of Sale</B></FONT></TD>
      <TD STYLE="vertical-align: top; border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><B>Name of Each Securities Exchange</B></FONT></TD></TR>
  <TR>
      <TD STYLE="vertical-align: top; border-bottom: black 1pt solid; border-left: black 1.5pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="vertical-align: top; border-right: black 1.5pt solid; border-left: black 1.5pt solid; border-bottom: black 1pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><B>&nbsp;</B></FONT></TD>
      <TD STYLE="vertical-align: top; border-bottom: black 1pt solid; background-color: gainsboro; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="vertical-align: bottom; border-right: black 1.5pt solid; border-left: black 1.5pt solid; border-bottom: black 1pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><I>(See instr. 3(c))</I></FONT></TD>
      <TD STYLE="vertical-align: bottom; border-bottom: black 1pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><I>(See instr. 3(d))</I></FONT></TD>
      <TD STYLE="vertical-align: bottom; border-right: black 1.5pt solid; border-left: black 1.5pt solid; border-bottom: black 1pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><I>(See instr. 3(e))</I></FONT></TD>
      <TD STYLE="vertical-align: top; border-bottom: black 1pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><I>(See instr. 3(f))<BR>
  </I>(MO. DAY YR.)</FONT></TD>
      <TD STYLE="vertical-align: bottom; border-right: black 1.5pt solid; border-left: black 1.5pt solid; border-bottom: black 1pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><I>(See instr. 3(g))</I></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: black 1pt solid; border-left: black 1.5pt solid; padding: 1.5pt">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">Common</P>
          <P STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; margin: 0">&nbsp;</P></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; border-bottom: black 1pt solid; padding-right: 1.5pt; padding-bottom: 1.5pt; padding-left: 1.5pt">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">Morgan Stanley<BR>
  
  1300 Thames Street<BR>
  
  Thames Street Wharf, 3rd Floor<BR>
  
  Baltimore, MD 21231
  </P>
          <P STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; margin: 0">&nbsp;</P></TD>
      <TD STYLE="border-bottom: black 1pt solid; background-color: gainsboro; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding: 1.5pt; border-bottom: black 1pt solid">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">97,576</P>
          <P STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; margin: 0; text-align: center">&nbsp;</P></TD>
      <TD STYLE="border-bottom: black 1pt solid; padding: 1.5pt">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">$2,280,355</P>
          <P STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; margin: 0; text-align: center">&nbsp;</P></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding: 1.5pt; border-bottom: black 1pt solid">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">78,992,871</P>
          <P STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; margin: 0; text-align: center">&nbsp;</P></TD>
      <TD STYLE="border-bottom: black 1pt solid; padding: 1.5pt">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">4/9/2020</P>
          <P STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; margin: 0; text-align: center">&nbsp;</P></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding: 1.5pt; border-bottom: black 1pt solid">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">NASDAQ</P>
          <P STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; margin: 0; text-align: center">&nbsp;</P></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: black 1pt solid; border-left: black 1.5pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; border-bottom: black 1pt solid; padding-right: 1.5pt; padding-bottom: 1.5pt; padding-left: 1.5pt">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
          <P STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; margin: 0">&nbsp;</P></TD>
      <TD STYLE="border-bottom: black 1pt solid; background-color: gainsboro; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding: 1.5pt; border-bottom: black 1pt solid">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P></TD>
      <TD STYLE="border-bottom: black 1pt solid; padding: 1.5pt">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center"></P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding: 1.5pt; border-bottom: black 1pt solid">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center"></P>
          <P STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; margin: 0; text-align: center">&nbsp;</P></TD>
      <TD STYLE="border-bottom: black 1pt solid; padding: 1.5pt">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center"></P>
          <P STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; margin: 0; text-align: center">&nbsp;</P></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding: 1.5pt; border-bottom: black 1pt solid">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center"></P>
          <P STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; margin: 0; text-align: center">&nbsp;</P></TD></TR>
  </TABLE>
  <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
      <TD COLSPAN="3"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><B>INSTRUCTIONS:</B></FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD COLSPAN="2"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">1.</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">(a)&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Name of issuer</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">3.</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">(a)&nbsp;</FONT></TD>
      <TD COLSPAN="2"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Title of the class of securities to be sold</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">(b)</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Issuer&rsquo;s I.R.S. Identification Number</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">(b)</FONT></TD>
      <TD COLSPAN="2"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Name and address of each broker through whom the securities are intended to be sold</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">(c)</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Issuer&rsquo;s S.E.C. file number, if any</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">(c)</FONT></TD>
      <TD COLSPAN="2"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Number of shares or other units to be sold (if debt securities, give the aggregate face amount)</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">(d)</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Issuer&rsquo;s address, including zip code</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">(d)</FONT></TD>
      <TD COLSPAN="2"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Aggregate market value of the securities to be sold as of a specified date within 10 days prior to filing of this notice</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">(e)</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Issuer&rsquo;s telephone number, including area code</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">(e)</FONT></TD>
      <TD COLSPAN="2"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Number of shares or other units of the class outstanding, or if debt securities the face amount thereof outstanding, as shown by the most recent report or statement published by the issuer</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">(f)</FONT></TD>
      <TD COLSPAN="2"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Approximate date on which the securities are to be sold</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">2.</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">(a)</FONT></TD>
      <TD COLSPAN="2"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Name of person for whose account the securities are to be sold</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">(g)</FONT></TD>
      <TD COLSPAN="2"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Name of each securities exchange, if any, on which the securities are intended to be sold</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">(b)</FONT></TD>
      <TD COLSPAN="2"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Such person&rsquo;s relationship to the issuer (e.g., officer, director, 10% stockholder, or member of immediate family of any of the foregoing)</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD COLSPAN="2"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">(c)</FONT></TD>
      <TD COLSPAN="2"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Such person&rsquo;s address, including zip code</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD COLSPAN="2"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD COLSPAN="7"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><B>Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.</B></FONT></TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">SEC 1147 (08-08)</FONT></TD></TR>
  <TR>
      <TD STYLE="width: 2%">&nbsp;</TD>
      <TD STYLE="width: 2%">&nbsp;</TD>
      <TD STYLE="width: 34%">&nbsp;</TD>
      <TD STYLE="width: 1%">&nbsp;</TD>
      <TD STYLE="width: 2%">&nbsp;</TD>
      <TD STYLE="width: 2%">&nbsp;</TD>
      <TD STYLE="width: 47%">&nbsp;</TD>
      <TD STYLE="width: 10%">&nbsp;</TD></TR>
  </TABLE>
  <P STYLE="font: 5pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>TABLE I &mdash; SECURITIES TO BE SOLD</B></P>
  
  <P STYLE="font: 2pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>
  <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center"><I>Furnish the following information with respect
  to the acquisition of the securities to be sold</I></P>
  
  <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center"><I>and with respect to the payment of all or
  any part of the purchase price or other consideration therefor:</I></P>
  
  <P STYLE="font: 8pt Calibri, Helvetica, Sans-Serif; margin: 0; text-align: center">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 11pt Calibri, Helvetica, Sans-Serif; border-collapse: collapse">
  <TR>
      <TD STYLE="width: 12%; border-top: black 1.5pt solid; border-bottom: black 1pt solid; border-left: black 1.5pt solid; padding: 1.5pt">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">Title of</P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">the Class</P></TD>
      <TD STYLE="width: 12%; border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-left: black 1.5pt solid; border-bottom: black 1pt solid; padding: 1.5pt">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">Date you</P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">Acquired</P></TD>
      <TD STYLE="width: 23%; border-top: black 1.5pt solid; border-bottom: black 1pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Nature of Acquisition Transaction</FONT></TD>
      <TD STYLE="width: 20%; border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-left: black 1.5pt solid; border-bottom: black 1pt solid; padding: 1.5pt">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">Name of Person from Whom Acquired</P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">(<I>If gift, also give date donor acquired</I>)</P></TD>
      <TD STYLE="width: 12%; border-top: black 1.5pt solid; border-bottom: black 1pt solid; padding: 1.5pt">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">Amount of</P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">Securities Acquired</P></TD>
      <TD STYLE="width: 9%; border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-left: black 1.5pt solid; border-bottom: black 1pt solid; padding: 1.5pt">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">Date of</P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">Payment</P></TD>
      <TD STYLE="width: 12%; border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-bottom: black 1pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Nature of Payment</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: black 1pt solid; border-left: black 1.5pt solid; padding: 1.5pt">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">Common Stock </P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
          <P STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; margin: 0">&nbsp;</P></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding: 1.5pt; border-bottom: black 1pt solid">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">More than 1 year</P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P></TD>
      <TD STYLE="border-bottom: black 1pt solid; padding: 1.5pt">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">Private Placement</P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding: 1.5pt; border-bottom: black 1pt solid">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">Issuer</P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P></TD>
      <TD STYLE="border-bottom: black 1pt solid; padding: 1.5pt">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">97,576</P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding: 1.5pt; border-bottom: black 1pt solid">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">More than 1 year</P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1pt solid; padding: 1.5pt">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">Cash</P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P></TD></TR>
  </TABLE>
  <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 11pt Calibri, Helvetica, Sans-Serif; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 19%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><B>INSTRUCTIONS:</B></FONT></TD>
      <TD STYLE="width: 1%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="width: 80%; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.</FONT></TD></TR>
  </TABLE>
  <!-- Field: Rule-Page --><DIV STYLE="margin-top: 1pt; margin-bottom: 1pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 0.5pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->
  
  <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>TABLE II &mdash; SECURITIES SOLD DURING THE
  PAST 3 MONTHS</B></P>
  
  <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center"><I>Furnish the following information as to all
  securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.</I></P>
  
  <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 11pt Calibri, Helvetica, Sans-Serif; border-collapse: collapse">
  <TR>
      <TD STYLE="width: 35%; border-top: black 1.5pt solid; border-bottom: black 1pt solid; border-left: black 1.5pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Name and Address of Seller</FONT></TD>
      <TD STYLE="width: 24%; border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-left: black 1.5pt solid; border-bottom: black 1pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Title of Securities Sold</FONT></TD>
      <TD STYLE="width: 10%; border-top: black 1.5pt solid; border-bottom: black 1pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Date of Sale</FONT></TD>
      <TD STYLE="width: 14%; border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-left: black 1.5pt solid; border-bottom: black 1pt solid; padding: 1.5pt">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">Amount of</P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">Securities Sold</P></TD>
      <TD STYLE="width: 17%; border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-bottom: black 1pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Gross Proceeds</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: black 1pt solid; border-left: black 1.5pt solid; padding-right: 1.5pt; padding-bottom: 1.5pt; padding-left: 1.5pt">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0 0 0 9pt">OrbiMed Private Investments IV - AL (Feeder), LP<BR>
  
  c/o OrbiMed Advisors LLC<BR>
  
  601 Lexington Avenue, 54th Floor<BR>
  
  New York, NY 10022
  </P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0 0 0 9pt">&nbsp;</P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0 0 0 9pt">&nbsp;</P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0 0 0 9pt">&nbsp;</P></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding: 1.5pt; border-bottom: black 1pt solid">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">Common Stock</P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P></TD>
      <TD STYLE="border-bottom: black 1pt solid; padding: 1.5pt">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">3/2/20<BR>
  <BR>
  
  
  3/23/20<BR>
  <BR>
  
  
  3/24/20<BR>
  <BR>
  
  
  3/25/20<BR>
  <BR>
  
  
  3/31/20<BR>
  <BR>
  
  
  4/7/20<BR>
  <BR>
  
  
  4/8/20
  </P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding: 1.5pt; border-bottom: black 1pt solid">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">445,086<BR>
  <BR>
  
  
  3,541<BR>
  <BR>
  
  
  16,409<BR>
  <BR>
  
  
  13,684<BR>
  <BR>
  
  
  60,645<BR>
  <BR>
  
  
  2,224<BR>
  <BR>
  
  
  20,041
  </P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P></TD>
      <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1pt solid; padding: 1.5pt">
          <P STYLE="text-align: center; font: 8pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0">$11,572,980<BR>
  <BR>
  
  
  $92,230<BR>
  <BR>
  
  
  $401,166<BR>
  <BR>
  
  
  $337,454<BR>
  <BR>
  
  
  $1,485,856<BR>
  <BR>
  
  
  $51,378<BR>
  <BR>
  
  
  $473,996
  </P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
          <P STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; margin: 0">&nbsp;</P></TD></TR>
  </TABLE>
  <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0"><B>REMARKS:</B></P>
  
  <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 11pt Calibri, Helvetica, Sans-Serif; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 51%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><B>INSTRUCTIONS:</B></FONT></TD>
      <TD STYLE="width: 1%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="width: 48%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><B>ATTENTION:</B></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">See the definition of &ldquo;person&rdquo; in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><I>The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.</I></FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 11pt Calibri, Helvetica, Sans-Serif; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 4%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="width: 44%; border-bottom: black 1pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">4-9-2020</FONT></TD>
      <TD STYLE="width: 4%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="width: 4%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="width: 40%; border-bottom: black 1pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">/s/ Douglas Coon</FONT></TD>
      <TD STYLE="width: 4%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">DATE OF NOTICE</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">(SIGNATURE)</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">Douglas Coon<BR>
      Chief Compliance Officer of OrbiMed Advisors LLC, Managing Member of the General Partner of OrbiMed Private Investments IV - AL (Feeder), LP
  </font></TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="border-bottom: black 1pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">DATE OF PLAN ADOPTION OR GIVING OF INSTRUCTION,<BR>
  IF RELYING ON RULE 10B5-1</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD COLSPAN="3">
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center"><I>The notice shall be signed by the person for
          whose account the securities are to be sold. At least one </I></P>
          <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: center"><I>copy of the notice shall be manually signed.
          Any copies not manually signed shall bear typed or printed signatures.</I></P></TD></TR>
  </TABLE>
  <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 11pt Calibri, Helvetica, Sans-Serif; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 100%; border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-left: black 1.5pt solid; border-bottom: black 1pt solid; padding-top: 1.5pt; padding-right: 1.5pt; padding-left: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 8pt"><B>ATTENTION:&nbsp;&nbsp;Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)</B></FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0; text-align: right">SEC 1147 (02-08)</P>
  
  <!-- Field: Rule-Page --><DIV STYLE="margin-top: 1pt; margin-bottom: 1pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 0.5pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->
  
  
  
  <P STYLE="margin: 0"></P>
  
  </BODY>
  </HTML>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "ss171313_144.htm", "description": "NOTICE OF PROPOSED SALE OF SECURITIES", "secsgml_size_bytes": 54160}]
text: UNITED STATES
  OMB APPROVAL
  SECURITIES AND EXCHANGE COMMISSION
  OMB Number:
  3235-0101
  Washington, D.C. 20549
  Expires:
  June 30, 2020
  Estimated average burden
  FORM 144
  hours per response
  1.00
  NOTICE OF PROPOSED SALE OF SECURITIES
  SEC USE ONLY
  PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
  DOCUMENT SEQUENCE NO.
  CUSIP NUMBER
  ATTENTION:
  Transmit
          for filing 3 copies of this form concurrently with either placing an order with a broker to execute sale or executing a sale directly
          with a market maker.
  1
  (a)
  NAME OF ISSUER
  (Please type or print)
  (b)
  IRS IDENT. NO.
  (c)
  S.E.C. FILE NO.
  WORK LOCATION
  Alector, Inc.
  462702363
  001-38792
  1
  (d)
  ADDRESS OF ISSUER
  STREET
  CITY
  STATE
  ZIP CODE
  (e)
  TELEPHONE NO
  AREA CODE
  NUMBER
  131 Oyster Point Blvd, Suite 600
  South San Francisco
  CA
  94080
  415
  231-5660
  2
  (a)
  NAME OF PERSON FOR WHOSE ACCOUNT THE SECURITIES ARE TO BE SOLD
  (b)
  RELATIONSHIP TO ISSUER
  (c)
  ADDRESS STREET
  CITY
  STATE
  ZIP CODE
  OrbiMed Advisors LLC on behalf of OrbiMed Private Investments IV - AL (Feeder), LP
  Shareholder
  c/o OrbiMed Advisors LLC
  601 Lexington Avenue, 54th Floor
  New York
  NY
  10022
  INSTRUCTION: The person filing this notice
  should contact the issuer to obtain the I.R.S. Identification Number and the S.E.C. File Number.
  3 (
  a)
  (b)
  SEC USE ONLY
  (c)
  (d)
  (e)
  (f)
  (g)
  Title of the Class of Securities To Be Sold
  Name and Address of Each Broker Through Whom the Securities are to be Offered or Each Market Maker who is Acquiring the Securities
  Broker-Dealer
  File Number
  Number of Shares or Other Units To Be Sold
  Aggregate Market Value
  Number of Shares or Other Units Outstanding
  Approximate Date of Sale
  Name of Each Securities Exchange
  (See instr. 3(c))
  (See instr. 3(d))
  (See instr. 3(e))
  (See instr. 3(f))
  (MO. DAY YR.)
  (See instr. 3(g))
  Common
  Morgan Stanley
  1300 Thames Street
  Thames Street Wharf, 3rd Floor
  Baltimore, MD 21231
  97,576
  $2,280,355
  78,992,871
  4/9/2020
  NASDAQ
  INSTRUCTIONS:
  1.
  (a)
  Name of issuer
  3.
  (a)
  Title of the class of securities to be sold
  (b)
  Issuer's I.R.S. Identification Number
  (b)
  Name and address of each broker through whom the securities are intended to be sold
  (c)
  Issuer's S.E.C. file number, if any
  (c)
  Number of shares or other units to be sold (if debt securities, give the aggregate face amount)
  (d)
  Issuer's address, including zip code
  (d)
  Aggregate market value of the securities to be sold as of a specified date within 10 days prior to filing of this notice
  (e)
  Issuer's telephone number, including area code
  (e)
  Number of shares or other units of the class outstanding, or if debt securities the face amount thereof outstanding, as shown by the most recent report or statement published by the issuer
  (f)
  Approximate date on which the securities are to be sold
  2.
  (a)
  Name of person for whose account the securities are to be sold
  (g)
  Name of each securities exchange, if any, on which the securities are intended to be sold
  (b)
  Such person's relationship to the issuer (e.g., officer, director, 10% stockholder, or member of immediate family of any of the foregoing)
  (c)
  Such person's address, including zip code
  Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
  SEC 1147 (08-08)
  TABLE I — SECURITIES TO BE SOLD
  Furnish the following information with respect
  to the acquisition of the securities to be sold
  and with respect to the payment of all or
  any part of the purchase price or other consideration therefor:
  Title of
  the Class
  Date you
  Acquired
  Nature of Acquisition Transaction
  Name of Person from Whom Acquired
  (
  If gift, also give date donor acquired
  )
  Amount of
  Securities Acquired
  Date of
  Payment
  Nature of Payment
  Common Stock
  More than 1 year
  Private Placement
  Issuer
  97,576
  More than 1 year
  Cash
  INSTRUCTIONS:
  If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.
  TABLE II — SECURITIES SOLD DURING THE
  PAST 3 MONTHS
  Furnish the following information as to all
  securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.
  Name and Address of Seller
  Title of Securities Sold
  Date of Sale
  Amount of
  Securities Sold
  Gross Proceeds
  OrbiMed Private Investments IV - AL (Feeder), LP
  c/o OrbiMed Advisors LLC
  601 Lexington Avenue, 54th Floor
  New York, NY 10022
  Common Stock
  3/2/20
  3/23/20
  3/24/20
  3/25/20
  3/31/20
  4/7/20
  4/8/20
  445,086
  3,541
  16,409
  13,684
  60,645
  2,224
  20,041
  $11,572,980
  $92,230
  $401,166
  $337,454
  $1,485,856
  $51,378
  $473,996
  REMARKS:
  INSTRUCTIONS:
  ATTENTION:
  See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.
  The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.
  4-9-2020
  /s/ Douglas Coon
  DATE OF NOTICE
  (SIGNATURE)
  Douglas Coon
  Chief Compliance Officer of OrbiMed Advisors LLC, Managing Member of the General Partner of OrbiMed Private Investments IV - AL (Feeder), LP
  DATE OF PLAN ADOPTION OR GIVING OF INSTRUCTION,
  IF RELYING ON RULE 10B5-1
  The notice shall be signed by the person for
          whose account the securities are to be sold. At least one
  copy of the notice shall be manually signed.
          Any copies not manually signed shall bear typed or printed signatures.
  ATTENTION:  Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)
  SEC 1147 (02-08)