content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:xsd="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <headerData>
  <submissionType>144</submissionType>
  <filerInfo>
  <filer>
  <filerCredentials>
  <cik>0001757839</cik>
  <ccc>XXXXXXXX</ccc>
  </filerCredentials>
  </filer>
  <liveTestFlag>LIVE</liveTestFlag>
  </filerInfo>
  </headerData>
  <formData>
  <issuerInfo>
  <issuerCik>0001289945</issuerCik>
  <issuerName>Spok Holdings, Inc.</issuerName>
  <secFileNumber>001-32358</secFileNumber>
  <issuerAddress>
  <street1 xmlns="http://www.sec.gov/edgar/common">5911 KINGSTOWNE VILLAGE PARKWAY</street1>
  <street2 xmlns="http://www.sec.gov/edgar/common">6TH FLOOR</street2>
  <city xmlns="http://www.sec.gov/edgar/common">ALEXANDRIA</city>
  <stateOrCountry xmlns="http://www.sec.gov/edgar/common">VA</stateOrCountry>
  <zipCode xmlns="http://www.sec.gov/edgar/common">22315</zipCode>
  </issuerAddress>
  <issuerContactPhone>800-611-8488</issuerContactPhone>
  <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Calvin Rice</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
  <relationshipsToIssuer>
  <relationshipToIssuer>Officer</relationshipToIssuer>
  </relationshipsToIssuer>
  </issuerInfo>
  <securitiesInformation>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <brokerOrMarketmakerDetails>
  <name>Computershare</name>
  <address>
  <street1 xmlns="http://www.sec.gov/edgar/common">144 Fernwood Avenue</street1>
  <city xmlns="http://www.sec.gov/edgar/common">Edison</city>
  <stateOrCountry xmlns="http://www.sec.gov/edgar/common">NJ</stateOrCountry>
  <zipCode xmlns="http://www.sec.gov/edgar/common">08837</zipCode>
  </address>
  </brokerOrMarketmakerDetails>
  <noOfUnitsSold>13000</noOfUnitsSold>
  <aggregateMarketValue>223470</aggregateMarketValue>
  <noOfUnitsOutstanding>19981238</noOfUnitsOutstanding>
  <approxSaleDate>11/30/2023</approxSaleDate>
  <securitiesExchangeName>Nasdaq</securitiesExchangeName>
  </securitiesInformation>
  <securitiesToBeSold>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <acquiredDate>12/31/2018</acquiredDate>
  <natureOfAcquisitionTransaction>Restricted Stock Unit Vesting</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>452</amountOfSecuritiesAcquired>
  <paymentDate>12/31/2018</paymentDate>
  <natureOfPayment>Services Rendered</natureOfPayment>
  </securitiesToBeSold>
  <securitiesToBeSold>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <acquiredDate>03/08/2019</acquiredDate>
  <natureOfAcquisitionTransaction>Restricted Stock Unit Vesting</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>437</amountOfSecuritiesAcquired>
  <paymentDate>03/08/2019</paymentDate>
  <natureOfPayment>Services Rendered</natureOfPayment>
  </securitiesToBeSold>
  <securitiesToBeSold>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <acquiredDate>12/31/2019</acquiredDate>
  <natureOfAcquisitionTransaction>Restricted Stock Unit Vesting</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>943</amountOfSecuritiesAcquired>
  <paymentDate>12/31/2019</paymentDate>
  <natureOfPayment>Services Rendered</natureOfPayment>
  </securitiesToBeSold>
  <securitiesToBeSold>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <acquiredDate>03/06/2020</acquiredDate>
  <natureOfAcquisitionTransaction>Restricted Stock Unit Vesting</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>552</amountOfSecuritiesAcquired>
  <paymentDate>03/06/2020</paymentDate>
  <natureOfPayment>Services Rendered</natureOfPayment>
  </securitiesToBeSold>
  <securitiesToBeSold>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <acquiredDate>12/31/2020</acquiredDate>
  <natureOfAcquisitionTransaction>Restricted Stock Unit Vesting</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>1618</amountOfSecuritiesAcquired>
  <paymentDate>12/31/2020</paymentDate>
  <natureOfPayment>Services Rendered</natureOfPayment>
  </securitiesToBeSold>
  <securitiesToBeSold>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <acquiredDate>01/22/2021</acquiredDate>
  <natureOfAcquisitionTransaction>Common Stock Grant</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>135</amountOfSecuritiesAcquired>
  <paymentDate>01/22/2021</paymentDate>
  <natureOfPayment>Services Rendered</natureOfPayment>
  </securitiesToBeSold>
  <securitiesToBeSold>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <acquiredDate>02/26/2021</acquiredDate>
  <natureOfAcquisitionTransaction>Restricted Stock Unit Vesting</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>752</amountOfSecuritiesAcquired>
  <paymentDate>02/26/2021</paymentDate>
  <natureOfPayment>Services Rendered</natureOfPayment>
  </securitiesToBeSold>
  <securitiesToBeSold>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <acquiredDate>04/02/2021</acquiredDate>
  <natureOfAcquisitionTransaction>Common Stock Grant</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>170</amountOfSecuritiesAcquired>
  <paymentDate>04/02/2021</paymentDate>
  <natureOfPayment>Services Rendered</natureOfPayment>
  </securitiesToBeSold>
  <securitiesToBeSold>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <acquiredDate>07/09/2021</acquiredDate>
  <natureOfAcquisitionTransaction>Common Stock Grant</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>181</amountOfSecuritiesAcquired>
  <paymentDate>07/09/2021</paymentDate>
  <natureOfPayment>Services Rendered</natureOfPayment>
  </securitiesToBeSold>
  <securitiesToBeSold>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <acquiredDate>12/31/2021</acquiredDate>
  <natureOfAcquisitionTransaction>Restricted Stock Unit Vesting</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>1751</amountOfSecuritiesAcquired>
  <paymentDate>12/31/2021</paymentDate>
  <natureOfPayment>Services Rendered</natureOfPayment>
  </securitiesToBeSold>
  <securitiesToBeSold>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <acquiredDate>02/25/2022</acquiredDate>
  <natureOfAcquisitionTransaction>Restricted Stock Unit Vesting</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>1011</amountOfSecuritiesAcquired>
  <paymentDate>02/25/2022</paymentDate>
  <natureOfPayment>Services Rendered</natureOfPayment>
  </securitiesToBeSold>
  <securitiesToBeSold>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <acquiredDate>03/02/2023</acquiredDate>
  <natureOfAcquisitionTransaction>Restricted Stock Unit Vesting</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>1867</amountOfSecuritiesAcquired>
  <paymentDate>03/02/2023</paymentDate>
  <natureOfPayment>Services Rendered</natureOfPayment>
  </securitiesToBeSold>
  <securitiesToBeSold>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <acquiredDate>01/03/2023</acquiredDate>
  <natureOfAcquisitionTransaction>Restricted Stock Unit Vesting</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>3927</amountOfSecuritiesAcquired>
  <paymentDate>01/03/2023</paymentDate>
  <natureOfPayment>Services Rendered</natureOfPayment>
  </securitiesToBeSold>
  <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
  <noticeSignature>
  <noticeDate>11/30/2023</noticeDate>
  <signature>/s/ Calvin Rice</signature>
  </noticeSignature>
  </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 8665}]
text: 144
  0001757839
  XXXXXXXX
  LIVE
  0001289945
  Spok Holdings, Inc.
  001-32358
  5911 KINGSTOWNE VILLAGE PARKWAY
  6TH FLOOR
  ALEXANDRIA
  VA
  22315
  800-611-8488
  Calvin Rice
  Officer
  Common Stock
  Computershare
  144 Fernwood Avenue
  Edison
  NJ
  08837
  13000
  223470
  19981238
  11/30/2023
  Nasdaq
  Common Stock
  12/31/2018
  Restricted Stock Unit Vesting
  Issuer
  N
  452
  12/31/2018
  Services Rendered
  Common Stock
  03/08/2019
  Restricted Stock Unit Vesting
  Issuer
  N
  437
  03/08/2019
  Services Rendered
  Common Stock
  12/31/2019
  Restricted Stock Unit Vesting
  Issuer
  N
  943
  12/31/2019
  Services Rendered
  Common Stock
  03/06/2020
  Restricted Stock Unit Vesting
  Issuer
  N
  552
  03/06/2020
  Services Rendered
  Common Stock
  12/31/2020
  Restricted Stock Unit Vesting
  Issuer
  N
  1618
  12/31/2020
  Services Rendered
  Common Stock
  01/22/2021
  Common Stock Grant
  Issuer
  N
  135
  01/22/2021
  Services Rendered
  Common Stock
  02/26/2021
  Restricted Stock Unit Vesting
  Issuer
  N
  752
  02/26/2021
  Services Rendered
  Common Stock
  04/02/2021
  Common Stock Grant
  Issuer
  N
  170
  04/02/2021
  Services Rendered
  Common Stock
  07/09/2021
  Common Stock Grant
  Issuer
  N
  181
  07/09/2021
  Services Rendered
  Common Stock
  12/31/2021
  Restricted Stock Unit Vesting
  Issuer
  N
  1751
  12/31/2021
  Services Rendered
  Common Stock
  02/25/2022
  Restricted Stock Unit Vesting
  Issuer
  N
  1011
  02/25/2022
  Services Rendered
  Common Stock
  03/02/2023
  Restricted Stock Unit Vesting
  Issuer
  N
  1867
  03/02/2023
  Services Rendered
  Common Stock
  01/03/2023
  Restricted Stock Unit Vesting
  Issuer
  N
  3927
  01/03/2023
  Services Rendered
  Y
  11/30/2023
  /s/ Calvin Rice