content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:xsd="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
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  <filerInfo>
  <filer>
  <filerCredentials>
  <cik>0001418459</cik>
  <ccc>XXXXXXXX</ccc>
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  </filer>
  <liveTestFlag>LIVE</liveTestFlag>
  </filerInfo>
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  <formData>
  <issuerInfo>
  <issuerCik>0001142417</issuerCik>
  <issuerName>NEXSTAR MEDIA GROUP, INC.</issuerName>
  <secFileNumber>000-50478</secFileNumber>
  <issuerAddress>
  <street1 xmlns="http://www.sec.gov/edgar/common">545 E. John Carpenter Freeway</street1>
  <street2 xmlns="http://www.sec.gov/edgar/common">Suite 700</street2>
  <city xmlns="http://www.sec.gov/edgar/common">Irving</city>
  <stateOrCountry xmlns="http://www.sec.gov/edgar/common">TX</stateOrCountry>
  <zipCode xmlns="http://www.sec.gov/edgar/common">75062</zipCode>
  </issuerAddress>
  <issuerContactPhone> 972-373-8800</issuerContactPhone>
  <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Blake Russell</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
  <relationshipsToIssuer>
  <relationshipToIssuer>Officer</relationshipToIssuer>
  </relationshipsToIssuer>
  </issuerInfo>
  <securitiesInformation>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <brokerOrMarketmakerDetails>
  <name>Raymond James &amp; Associates, Inc.</name>
  <address>
  <street1 xmlns="http://www.sec.gov/edgar/common">880 Carillon Parkway</street1>
  <city xmlns="http://www.sec.gov/edgar/common">St. Petersburg</city>
  <stateOrCountry xmlns="http://www.sec.gov/edgar/common">FL</stateOrCountry>
  <zipCode xmlns="http://www.sec.gov/edgar/common">33716</zipCode>
  </address>
  </brokerOrMarketmakerDetails>
  <noOfUnitsSold>3000</noOfUnitsSold>
  <aggregateMarketValue>503473</aggregateMarketValue>
  <noOfUnitsOutstanding>35856653</noOfUnitsOutstanding>
  <approxSaleDate>06/27/2023</approxSaleDate>
  <securitiesExchangeName>NASDAQ</securitiesExchangeName>
  </securitiesInformation>
  <securitiesInformation>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <brokerOrMarketmakerDetails>
  <name>Raymond James &amp; Associates, Inc.</name>
  <address>
  <street1 xmlns="http://www.sec.gov/edgar/common">880 Carillon Parkway</street1>
  <city xmlns="http://www.sec.gov/edgar/common">St. Petersburg</city>
  <stateOrCountry xmlns="http://www.sec.gov/edgar/common">FL</stateOrCountry>
  <zipCode xmlns="http://www.sec.gov/edgar/common">33716</zipCode>
  </address>
  </brokerOrMarketmakerDetails>
  <noOfUnitsSold>3697</noOfUnitsSold>
  <aggregateMarketValue>602650</aggregateMarketValue>
  <noOfUnitsOutstanding>35856653</noOfUnitsOutstanding>
  <approxSaleDate>06/26/2023</approxSaleDate>
  <securitiesExchangeName>NASDAQ</securitiesExchangeName>
  </securitiesInformation>
  <securitiesToBeSold>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <acquiredDate>05/17/2022</acquiredDate>
  <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>1041</amountOfSecuritiesAcquired>
  <paymentDate>05/17/2022</paymentDate>
  <natureOfPayment>Cash</natureOfPayment>
  </securitiesToBeSold>
  <securitiesToBeSold>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <acquiredDate>04/10/2022</acquiredDate>
  <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>1516</amountOfSecuritiesAcquired>
  <paymentDate>04/10/2022</paymentDate>
  <natureOfPayment>Cash</natureOfPayment>
  </securitiesToBeSold>
  <securitiesToBeSold>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <acquiredDate>03/20/2022</acquiredDate>
  <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>443</amountOfSecuritiesAcquired>
  <paymentDate>03/20/2022</paymentDate>
  <natureOfPayment>Cash</natureOfPayment>
  </securitiesToBeSold>
  <securitiesToBeSold>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <acquiredDate>03/15/2022</acquiredDate>
  <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>2861</amountOfSecuritiesAcquired>
  <paymentDate>03/15/2022</paymentDate>
  <natureOfPayment>Cash</natureOfPayment>
  </securitiesToBeSold>
  <securitiesToBeSold>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <acquiredDate>03/20/2022</acquiredDate>
  <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>836</amountOfSecuritiesAcquired>
  <paymentDate>03/20/2022</paymentDate>
  <natureOfPayment>Cash</natureOfPayment>
  </securitiesToBeSold>
  <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
  <noticeSignature>
  <noticeDate>06/27/2023</noticeDate>
  <signature>Blake Russell</signature>
  </noticeSignature>
  </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 5430}]
text: 144
  0001418459
  XXXXXXXX
  LIVE
  0001142417
  NEXSTAR MEDIA GROUP, INC.
  000-50478
  545 E. John Carpenter Freeway
  Suite 700
  Irving
  TX
  75062
  972-373-8800
  Blake Russell
  Officer
  Common Stock
  Raymond James & Associates, Inc.
  880 Carillon Parkway
  St. Petersburg
  FL
  33716
  3000
  503473
  35856653
  06/27/2023
  NASDAQ
  Common Stock
  Raymond James & Associates, Inc.
  880 Carillon Parkway
  St. Petersburg
  FL
  33716
  3697
  602650
  35856653
  06/26/2023
  NASDAQ
  Common Stock
  05/17/2022
  Restricted Stock Vesting
  Issuer
  N
  1041
  05/17/2022
  Cash
  Common Stock
  04/10/2022
  Restricted Stock Vesting
  Issuer
  N
  1516
  04/10/2022
  Cash
  Common Stock
  03/20/2022
  Restricted Stock Vesting
  Issuer
  N
  443
  03/20/2022
  Cash
  Common Stock
  03/15/2022
  Restricted Stock Vesting
  Issuer
  N
  2861
  03/15/2022
  Cash
  Common Stock
  03/20/2022
  Restricted Stock Vesting
  Issuer
  N
  836
  03/20/2022
  Cash
  Y
  06/27/2023
  Blake Russell