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  <ccc>XXXXXXXX</ccc>
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  <liveTestFlag>LIVE</liveTestFlag>
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  <issuerCik>0001861560</issuerCik>
  <issuerName>Nuvalent, Inc.</issuerName>
  <secFileNumber>001-40671</secFileNumber>
  <issuerAddress>
  <street1 xmlns="http://www.sec.gov/edgar/common">One Broadway</street1>
  <street2 xmlns="http://www.sec.gov/edgar/common">14th Floor</street2>
  <city xmlns="http://www.sec.gov/edgar/common">Cambridge</city>
  <stateOrCountry xmlns="http://www.sec.gov/edgar/common">MA</stateOrCountry>
  <zipCode xmlns="http://www.sec.gov/edgar/common">02142</zipCode>
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  <issuerContactPhone>857-357-7000</issuerContactPhone>
  <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Bain Capital Life Sciences Fund II, L.P.</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
  <relationshipsToIssuer>
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  <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
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  <address>
  <street1 xmlns="http://www.sec.gov/edgar/common">200 West Street</street1>
  <city xmlns="http://www.sec.gov/edgar/common">New York</city>
  <stateOrCountry xmlns="http://www.sec.gov/edgar/common">NY</stateOrCountry>
  <zipCode xmlns="http://www.sec.gov/edgar/common">10282</zipCode>
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  <noOfUnitsSold>1114286</noOfUnitsSold>
  <aggregateMarketValue>104308312</aggregateMarketValue>
  <noOfUnitsOutstanding>65617305</noOfUnitsOutstanding>
  <approxSaleDate>12/11/2024</approxSaleDate>
  <securitiesExchangeName>NASDAQ</securitiesExchangeName>
  </securitiesInformation>
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  <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
  <acquiredDate>04/30/2021</acquiredDate>
  <natureOfAcquisitionTransaction>Purchase of preferred stock from the Issuer, which was automatically converted into shares of Class A Common Stock immediately prior to the closing of the Issuer's initial public offering</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>2400630</amountOfSecuritiesAcquired>
  <paymentDate>04/30/2021</paymentDate>
  <natureOfPayment>Cash</natureOfPayment>
  </securitiesToBeSold>
  <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
  <noticeSignature>
  <noticeDate>12/11/2024</noticeDate>
  <signature>/s/ Andrew Hack, as Partner of Bain Capital Life Sciences Investors, LLC</signature>
  </noticeSignature>
  </formData>
  </edgarSubmission>
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text: 144
  0001773187
  XXXXXXXX
  LIVE
  0001861560
  Nuvalent, Inc.
  001-40671
  One Broadway
  14th Floor
  Cambridge
  MA
  02142
  857-357-7000
  Bain Capital Life Sciences Fund II, L.P.
  Affiliate
  Class A Common Stock
  Goldman Sachs & Co. LLC
  200 West Street
  New York
  NY
  10282
  1114286
  104308312
  65617305
  12/11/2024
  NASDAQ
  Class A Common Stock
  04/30/2021
  Purchase of preferred stock from the Issuer, which was automatically converted into shares of Class A Common Stock immediately prior to the closing of the Issuer's initial public offering
  Issuer
  N
  2400630
  04/30/2021
  Cash
  Y
  12/11/2024
  /s/ Andrew Hack, as Partner of Bain Capital Life Sciences Investors, LLC