content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
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      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <!-- Field: Pseudo-Tag; ID: Name; Data: ORBIMED ADVISORS LLC -->
            <cik>0001055951</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
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      <issuerInfo>
        <issuerCik>0001787297</issuerCik>
        <issuerName>Passage BIO, Inc.</issuerName>
        <secFileNumber>001-39231</secFileNumber>
        <issuerAddress>
          <com:street1>One Commerce Square</com:street1>
          <com:street2>2005 Market Street, 39th Floor</com:street2>
          <com:city>Philadelphia</com:city>
          <com:stateOrCountry>PA</com:stateOrCountry>
          <com:zipCode>19103</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>267-866-0312</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>OrbiMed Private Investments VII, LP</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Stockholder</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>International Strategy &amp; Investment Group LLC</name>
          <address>
            <com:street1>666 5th Avenue</com:street1>
            <com:street2>11th Floor</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10103</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>787179</noOfUnitsSold>
        <aggregateMarketValue>301490.00</aggregateMarketValue>
        <noOfUnitsOutstanding>62148274</noOfUnitsOutstanding>
        <approxSaleDate>04/15/2025</approxSaleDate>
        <securitiesExchangeName>Nasdaq Stock Market</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <acquiredDate>03/03/2020</acquiredDate>
        <natureOfAcquisitionTransaction>IPO</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>787179</amountOfSecuritiesAcquired>
        <paymentDate>03/03/2020</paymentDate>
        <natureOfPayment>N/A</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <remarks>OrbiMed Capital GP VII LLC is the general partner of OrbiMed Private Investments VII, LP. OrbiMed Advisors LLC is the managing member of OrbiMed Capital GP VII LLC.</remarks>
      <noticeSignature>
        <noticeDate>04/15/2025</noticeDate>
        <signature>/s/ Douglas Coon, Chief Compliance Officer, OrbiMed Advisors LLC, managing member of the general partner of OrbiMed Private Investments VII, LP</signature>
      </noticeSignature>
    </formData>
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text: 144
  0001055951
  XXXXXXXX
  LIVE
  0001787297
  Passage BIO, Inc.
  001-39231
  One Commerce Square
  2005 Market Street, 39th Floor
  Philadelphia
  PA
  19103
  267-866-0312
  OrbiMed Private Investments VII, LP
  Stockholder
  Common Stock
  International Strategy & Investment Group LLC
  666 5th Avenue
  11th Floor
  New York
  NY
  10103
  787179
  301490.00
  62148274
  04/15/2025
  Nasdaq Stock Market
  Common Stock
  03/03/2020
  IPO
  Issuer
  N
  787179
  03/03/2020
  N/A
  Y
  OrbiMed Capital GP VII LLC is the general partner of OrbiMed Private Investments VII, LP. OrbiMed Advisors LLC is the managing member of OrbiMed Capital GP VII LLC.
  04/15/2025
  /s/ Douglas Coon, Chief Compliance Officer, OrbiMed Advisors LLC, managing member of the general partner of OrbiMed Private Investments VII, LP