content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <!-- Generated by Workiva -->
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001250333</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001327567</issuerCik>
        <issuerName>Palo Alto Networks, Inc.</issuerName>
        <secFileNumber>001-35594</secFileNumber>
        <issuerAddress>
          <com:street1>3000 Tannery Way</com:street1>
          <com:city>Santa Clara</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>95054</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>408-753-4000</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Nir Zuk</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Affiliate</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>J.P. Morgan Securities LLC</name>
          <address>
            <com:street1>390 Madison Avenue</com:street1>
            <com:street2>6th Floor</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10017</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>949828</noOfUnitsSold>
        <aggregateMarketValue>15982557.56</aggregateMarketValue>
        <noOfUnitsOutstanding>662100000</noOfUnitsOutstanding>
        <approxSaleDate>04/11/2025</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>03/07/2005</acquiredDate>
        <natureOfAcquisitionTransaction>Founder shares held by Hawk Family Trust Dtd 10/29/12</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>400000</amountOfSecuritiesAcquired>
        <paymentDate>03/07/2005</paymentDate>
        <natureOfPayment>N/A</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>09/13/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Gift to The Cliff Family Trust FBO Ameet Zuk-Tepman</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Nir Zuk</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>Y</isGiftTransaction>
        <donarAcquiredDate>06/22/2006</donarAcquiredDate>
        <amountOfSecuritiesAcquired>109962</amountOfSecuritiesAcquired>
        <paymentDate>09/13/2022</paymentDate>
        <natureOfPayment>Gift</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>09/13/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Gift to The Cliff Family Trust FBO Danielle Zuk-Tepman</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Nir Zuk</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>Y</isGiftTransaction>
        <donarAcquiredDate>06/22/2006</donarAcquiredDate>
        <amountOfSecuritiesAcquired>109962</amountOfSecuritiesAcquired>
        <paymentDate>09/13/2022</paymentDate>
        <natureOfPayment>Gift</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>09/13/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Gift to The Cliff Family Trust FBO Guy Zuk</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Nir Zuk</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>Y</isGiftTransaction>
        <donarAcquiredDate>06/22/2006</donarAcquiredDate>
        <amountOfSecuritiesAcquired>109968</amountOfSecuritiesAcquired>
        <paymentDate>09/13/2022</paymentDate>
        <natureOfPayment>Gift</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>09/13/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Gift to The Cliff Family Trust FBO Maayan Haziza</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Nir Zuk</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>Y</isGiftTransaction>
        <donarAcquiredDate>06/22/2006</donarAcquiredDate>
        <amountOfSecuritiesAcquired>109968</amountOfSecuritiesAcquired>
        <paymentDate>09/13/2022</paymentDate>
        <natureOfPayment>Gift</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>09/13/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Gift to The Cliff Family Trust FBO Maya Zuk</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Nir Zuk</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>Y</isGiftTransaction>
        <donarAcquiredDate>06/22/2006</donarAcquiredDate>
        <amountOfSecuritiesAcquired>109968</amountOfSecuritiesAcquired>
        <paymentDate>09/13/2022</paymentDate>
        <natureOfPayment>Gift</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <remarks>The shares covered by this filing are shares expected to be sold within 3 months of this filing by Hawk Family Trust Dtd 10/29/12 (Nir Zuk as Trustee), The Cliff Family Trust FBO Ameet Zuk-Tepman, The Cliff Family Trust FBO Danielle Zuk-Tepman, The Cliff Family Trust FBO Guy Zuk, The Cliff Family Trust FBO Maayan Haziza, The Cliff Family Trust FBO Maya Zuk (J. P. Morgan Trust Company of Delaware as Trustee)</remarks>
      <noticeSignature>
        <noticeDate>04/11/2025</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>01/09/2025</planAdoptionDate>
        </planAdoptionDates>
        <signature>/s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Nir Zuk</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 6481}]
text: 144
  0001250333
  XXXXXXXX
  LIVE
  0001327567
  Palo Alto Networks, Inc.
  001-35594
  3000 Tannery Way
  Santa Clara
  CA
  95054
  408-753-4000
  Nir Zuk
  Affiliate
  Common
  J.P. Morgan Securities LLC
  390 Madison Avenue
  6th Floor
  New York
  NY
  10017
  949828
  15982557.56
  662100000
  04/11/2025
  NASDAQ
  Common
  03/07/2005
  Founder shares held by Hawk Family Trust Dtd 10/29/12
  Issuer
  N
  400000
  03/07/2005
  N/A
  Common
  09/13/2022
  Gift to The Cliff Family Trust FBO Ameet Zuk-Tepman
  Nir Zuk
  Y
  06/22/2006
  109962
  09/13/2022
  Gift
  Common
  09/13/2022
  Gift to The Cliff Family Trust FBO Danielle Zuk-Tepman
  Nir Zuk
  Y
  06/22/2006
  109962
  09/13/2022
  Gift
  Common
  09/13/2022
  Gift to The Cliff Family Trust FBO Guy Zuk
  Nir Zuk
  Y
  06/22/2006
  109968
  09/13/2022
  Gift
  Common
  09/13/2022
  Gift to The Cliff Family Trust FBO Maayan Haziza
  Nir Zuk
  Y
  06/22/2006
  109968
  09/13/2022
  Gift
  Common
  09/13/2022
  Gift to The Cliff Family Trust FBO Maya Zuk
  Nir Zuk
  Y
  06/22/2006
  109968
  09/13/2022
  Gift
  Y
  The shares covered by this filing are shares expected to be sold within 3 months of this filing by Hawk Family Trust Dtd 10/29/12 (Nir Zuk as Trustee), The Cliff Family Trust FBO Ameet Zuk-Tepman, The Cliff Family Trust FBO Danielle Zuk-Tepman, The Cliff Family Trust FBO Guy Zuk, The Cliff Family Trust FBO Maayan Haziza, The Cliff Family Trust FBO Maya Zuk (J. P. Morgan Trust Company of Delaware as Trustee)
  04/11/2025
  01/09/2025
  /s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Nir Zuk