content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
  <submissionType>144</submissionType>
  <filerInfo>
  <filer>
  <filerCredentials>
  <cik>0001988588</cik>
  <ccc>XXXXXXXX</ccc>
  </filerCredentials>
  </filer>
  <liveTestFlag>LIVE</liveTestFlag>
  
  
  
  </filerInfo>
  </headerData>
  <formData>
  <issuerInfo>
  <issuerCik>0001503584</issuerCik>
  <issuerName>Costamare Inc.</issuerName>
  <secFileNumber>001-34934</secFileNumber>
  <issuerAddress>
  <com:street1>7 rue du Gabian</com:street1>
  <com:city>MC</com:city>
  <com:stateOrCountry>O9</com:stateOrCountry>
  <com:zipCode>98000</com:zipCode>
  </issuerAddress>
  <issuerContactPhone>377 9 3 25 09 40</issuerContactPhone>
  <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Konstantinos Zacharatos</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
  <relationshipsToIssuer>
  <relationshipToIssuer>Director</relationshipToIssuer>
  </relationshipsToIssuer>
  </issuerInfo>
  <securitiesInformation>
  <securitiesClassTitle>COMMON SHARES</securitiesClassTitle>
  <brokerOrMarketmakerDetails>
  <name>HSBC UK Bank plc</name>
  <address>
  <com:street1>1 Centenary Place</com:street1>
  <com:city>Birmingham</com:city>
  <com:stateOrCountry>X0</com:stateOrCountry>
  <com:zipCode>B1 1HQ</com:zipCode>
  </address>
  </brokerOrMarketmakerDetails>
  <noOfUnitsSold>38000</noOfUnitsSold>
  <aggregateMarketValue>653220</aggregateMarketValue>
  <noOfUnitsOutstanding>118944401</noOfUnitsOutstanding>
  <approxSaleDate>06/26/2024</approxSaleDate>
  <securitiesExchangeName>NYSE</securitiesExchangeName>
  </securitiesInformation>
  <securitiesInformation>
  <securitiesClassTitle>COMMON SHARES</securitiesClassTitle>
  <brokerOrMarketmakerDetails>
  <name>Bordier &amp; Cie SCmA</name>
  <address>
  <com:street1>Rue Rath 16</com:street1>
  <com:city>Geneva</com:city>
  <com:stateOrCountry>V8</com:stateOrCountry>
  <com:zipCode>1204</com:zipCode>
  </address>
  </brokerOrMarketmakerDetails>
  <noOfUnitsSold>4000</noOfUnitsSold>
  <aggregateMarketValue>68760</aggregateMarketValue>
  <noOfUnitsOutstanding>118944401</noOfUnitsOutstanding>
  <approxSaleDate>06/26/2024</approxSaleDate>
  <securitiesExchangeName>NYSE</securitiesExchangeName>
  </securitiesInformation>
  <securitiesToBeSold>
  <securitiesClassTitle>COMMON SHARES</securitiesClassTitle>
  <acquiredDate>05/30/2023</acquiredDate>
  <natureOfAcquisitionTransaction>Open Market Purchase</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Open Market</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>8000</amountOfSecuritiesAcquired>
  <paymentDate>05/30/2023</paymentDate>
  <natureOfPayment>Cash</natureOfPayment>
  </securitiesToBeSold>
  <securitiesToBeSold>
  <securitiesClassTitle>COMMON SHARES</securitiesClassTitle>
  <acquiredDate>05/31/2023</acquiredDate>
  <natureOfAcquisitionTransaction>Open Market Purchase</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Open Market</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>30000</amountOfSecuritiesAcquired>
  <paymentDate>05/31/2023</paymentDate>
  <natureOfPayment>Cash</natureOfPayment>
  </securitiesToBeSold>
  <securitiesToBeSold>
  <securitiesClassTitle>COMMON SHARES</securitiesClassTitle>
  <acquiredDate>09/22/2021</acquiredDate>
  <natureOfAcquisitionTransaction>Open Market Purchase</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Open Market</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>4000</amountOfSecuritiesAcquired>
  <paymentDate>09/22/2021</paymentDate>
  <natureOfPayment>Cash</natureOfPayment>
  </securitiesToBeSold>
  <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
  <securitiesSoldInPast3Months>
  <sellerDetails>
  <name>Konstantinos Zacharatos</name>
  <address>
  <com:street1>60 Zephyrou Street &amp; Syngrou Avenue</com:street1>
  <com:city>Athens</com:city>
  <com:stateOrCountry>J3</com:stateOrCountry>
  <com:zipCode>17564</com:zipCode>
  </address>
  </sellerDetails>
  <securitiesClassTitle>Common Shares</securitiesClassTitle>
  <saleDate>06/24/2024</saleDate>
  <amountOfSecuritiesSold>20000</amountOfSecuritiesSold>
  <grossProceeds>339239.21</grossProceeds>
  </securitiesSoldInPast3Months>
  <remarks>Aggregate Market Value of shares calculated based on a closing share price of $17.19 on June 25, 2024.</remarks>
  <noticeSignature>
  <noticeDate>06/26/2024</noticeDate>
  <signature>/s/ Konstantinos Zacharatos</signature>
  </noticeSignature>
  </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 4548}]
text: 144
  0001988588
  XXXXXXXX
  LIVE
  0001503584
  Costamare Inc.
  001-34934
  7 rue du Gabian
  MC
  O9
  98000
  377 9 3 25 09 40
  Konstantinos Zacharatos
  Director
  COMMON SHARES
  HSBC UK Bank plc
  1 Centenary Place
  Birmingham
  X0
  B1 1HQ
  38000
  653220
  118944401
  06/26/2024
  NYSE
  COMMON SHARES
  Bordier & Cie SCmA
  Rue Rath 16
  Geneva
  V8
  1204
  4000
  68760
  118944401
  06/26/2024
  NYSE
  COMMON SHARES
  05/30/2023
  Open Market Purchase
  Open Market
  N
  8000
  05/30/2023
  Cash
  COMMON SHARES
  05/31/2023
  Open Market Purchase
  Open Market
  N
  30000
  05/31/2023
  Cash
  COMMON SHARES
  09/22/2021
  Open Market Purchase
  Open Market
  N
  4000
  09/22/2021
  Cash
  N
  Konstantinos Zacharatos
  60 Zephyrou Street & Syngrou Avenue
  Athens
  J3
  17564
  Common Shares
  06/24/2024
  20000
  339239.21
  Aggregate Market Value of shares calculated based on a closing share price of $17.19 on June 25, 2024.
  06/26/2024
  /s/ Konstantinos Zacharatos