content: UNITED STATES
  SECURITIES AND EXCHANGE COMMISSION
  Washington, D.C. 20549
  
  OMB APPROVAL
  
  OMB Number:  3235-0101
  Expires: March 31, 2011
  Estimated average burden
  hours per response      2.0
  
  FORM 144
  NOTICE OF PROPOSED SALE OF SECURITIES
  PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
  
  
  SEC USE ONLY
  
  DOCUMENT SEQUENCE NO.
  
  CUSIP NUMBER
  
  WORK LOCATION
  
  
  NOTICE OF PROPOSED SALE OF SECURITIES
  PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
  
  
  ATTENTION:
  Transmit for filing 3 copies of this form concurrently with either placing
  an order with a broker to execute sale or executing a sale directly
  with a market maker.
  
  
  1(a) NAME OF ISSUER (Please type or print)
  
       Tekelec
  
  (b)  IRS IDENT. NO.
  
       95-2746131
  
  (c)  S.E.C. FILE NO.
  
       000-15135
  
  
  1(d) ADDRESS OF ISSUER: 5200 Paramount Parkway Morrisville    NC   27560
  
  
  (e) TELEPHONE NUMBER: 919-460-5500
  
  2(a) NAME OF PERSON FOR WHOSE ACCOUNT THE SECURITIES ARE TO BE SOLD
  
      Hubert de Pesquidoux
  
  (b) RELATIONSHIP TO ISSUER:  Director
  
  (c) ADDRESS: c/o Tekelec, 5200 Paramount Parkway, Morrisville, NC  27560
  
  
  INSTRUCTION:  The person filing this notice should contact the issuer to
  obtain the I.R.S. Identification Number and the S.E.C. File Number.
  
  3(a)  Title of the Class of Securities To Be Sold
  
        Common Stock
  
  (b)   Name and Address of Each Broker Through Whom the Securities
        are to be Offered or Each Market Maker who is Acquiring the Securities
  
        E*Trade Financial
        4005 Windward Plaza Drive
        Alpharetta, GA  30005
  
  
  SEC USE ONLY
  
  Broker-Dealer File Number:
  
  
  (c)  Number of Shares or Other Units To Be Sold: 1,000
  
  (d)  Aggregate Market Value:  $13,330.00  (11/09/10)
  
  (e)  Number of Shares or Other Units Outstanding: 68,585,311
  
  (f)  Approximate Date of Sale: 11/11/2010
  
  (g)  Name of Each Securities Exchange: NASDAQ
  
  
  
  INSTRUCTIONS:
  
  1.	(a)	Name of issuer
  	(b)	Issuer's I.R.S. Identification Number
          (c)	Issuer's S.E.C. file number, if any
  	(d)	Issuer's address, including zip code
  	(e)	Issuer's telephone number, including area code
  
  2.	(a)	Name of person for whose account the securities are to be sold
  	(b)	Such person's relationship to the issuer (e.g., officer, director,
  10% stockholder, or member of immediate family of any of the foregoing)
  	(c)	Such person's address, including zip code
  
  3.	(a)	Title of the class of securities to be sold
  	(b)	Name and address of each broker through whom the securities
  are intended to be sold
  	(c)	Number of shares or other units to be sold (if debt securities,
  give the aggregate face amount)
  	(d)	Aggregate market value of the securities to be sold as of a
  specified date within 10 days prior to the filing of this notice
  	(e)	Number of shares or other units of the class outstanding,
  or if debt securities the face amount thereof outstanding, as shown by
  the most recent report or statement published by the issuer
  	(f)	Approximate date on which the securities are to be sold
  	(g)	Name of each securities exchange, if any, on which the securities
  are intended to be sold
  
  
  
  TABLE I - SECURITIES TO BE SOLD
  Furnish the following information with respect to the acquisition of the
  securities to be sold and with respect to the payment of all or any part
  of the purchase price or other consideration therefor:
  
  Title of the Class: Common Stock
  
  Date you Acquired: 05/14/10
  
  Nature of Acquisition Transaction: Acquired upon vesting of Restricted
  Stock Units  (Remark #1)
  
  Name of Person from Whom Acquired (if gift, also give date donor acquired):
  
      Issuer
  
  Amount of Securities Acquired: 1,000
  
  Date of Payment: (Remark #2)
  
  Nature of Payment: (Remark #2)
  
  
  INSTRUCTIONS:	If the securities were purchased and full payment therefor
  was not made in cash at the time of purchase, explain in the table or
  in a note thereto the nature of the consideration given.  If the
  consideration consisted of any note or other obligation, or if payment
  was made in installments describe the arrangement and state when the
  note or other obligation was discharged in full or the last installment
  paid.
  
  
  
  TABLE II - SECURITIES SOLD DURING THE PAST 3 MONTHS
  Furnish the following information with respect to the acquisition of the
  securities to be sold and with respect to the payment of all or any part
  of the purchase price or other consideration therefor:
  
  
  Name and Address of Seller:
  
    NONE
  
  Title of Securities Sold:
  
  Date of Sale:
  
  Amount of Securities Sold:
  
  Gross Proceeds:
  
  
  REMARKS:
  (1)Shares acquired are registered under a Registration Statement on Form S-8.
  (2)Shares acquired upon vesting of Restricted Stock Units awarded to reporting
  person as a director of the issuer and no payment was required by the Seller
  in connection therewith.
  
  
  
  INSTRUCTIONS: See the definition of "person" in paragraph (a) of Rule 144.
  Information is to be given not only as to the person for whose account
  the securities are to be sold but also as to all other persons included
  in that definition.  In addition, information shall be given as to sales
  by all persons whose sales are required by paragraph (e) of Rule 144
  to be aggregated with sales for the account of the person filing this
  notice.
  
  ATTENTION:  The person for whose account the securities to which this
  notice relates are to be sold hereby represents by signing this notice
  that he does not know any material adverse information in regard to the
  current and prospective operations of the Issuer of the securities to
  be sold which has not been publicly disclosed.  If each person has
  adopted a written trading plan or given trading instructions to satisfy
  Rule 10b5-1 under the Exchange Act, by singing the form and indicating
  the date that the plan was adopted or the instruction given, that person
  makes such representation as of the plan adoption or instruction date.
  
  
  DATE OF NOTICE:  November 10, 2010
  
  /s/ Hubert de Pesquidoux
  ____________________
  Hubert de Pesquidoux
  (SIGNATURE)
  
  
  DATE OF PLAN ADOPTION OR GIVING OF INSTRUCTION,
  IF RELYING ON RULE 10B5-1: September 2, 2010
  
  
  The notice shall be signed by the person for whose account the securities
  are to be sold.  At least one copy of the notice shall be manually signed.
  Any copies not manually signed shall bear typed or printed signatures.
  
  
  ATTENTION:  Intentional misstatements or omission of facts constitute
  Federal Criminal Violations (See 18 U.S.C. 1001)
  
  SM01DOCS\667695.1	SEC 1147 (08-07)
  	Potential persons who are to respond to the collection of information
  contained in this form are not required to respond unless the form displays a
  currently valid OMB control number.
  SM01DOCS667695.1											SEC 1147 (04-07)
metadata_documents: [{"type": "144", "sequence": "1", "filename": "form144depesquidoux111010.txt", "description": "FORM 144 DEPESQIDOUX 111010", "secsgml_size_bytes": 6602}]
text: UNITED STATES
  SECURITIES AND EXCHANGE COMMISSION
  Washington, D.C. 20549
  
  OMB APPROVAL
  
  OMB Number:  3235-0101
  Expires: March 31, 2011
  Estimated average burden
  hours per response      2.0
  
  FORM 144
  NOTICE OF PROPOSED SALE OF SECURITIES
  PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
  
  SEC USE ONLY
  
  DOCUMENT SEQUENCE NO.
  
  CUSIP NUMBER
  
  WORK LOCATION
  
  NOTICE OF PROPOSED SALE OF SECURITIES
  PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
  
  ATTENTION:
  Transmit for filing 3 copies of this form concurrently with either placing
  an order with a broker to execute sale or executing a sale directly
  with a market maker.
  
  1(a) NAME OF ISSUER (Please type or print)
  
       Tekelec
  
  (b)  IRS IDENT. NO.
  
       95-2746131
  
  (c)  S.E.C. FILE NO.
  
       000-15135
  
  1(d) ADDRESS OF ISSUER: 5200 Paramount Parkway Morrisville    NC   27560
  
  (e) TELEPHONE NUMBER: 919-460-5500
  
  2(a) NAME OF PERSON FOR WHOSE ACCOUNT THE SECURITIES ARE TO BE SOLD
  
      Hubert de Pesquidoux
  
  (b) RELATIONSHIP TO ISSUER:  Director
  
  (c) ADDRESS: c/o Tekelec, 5200 Paramount Parkway, Morrisville, NC  27560
  
  INSTRUCTION:  The person filing this notice should contact the issuer to
  obtain the I.R.S. Identification Number and the S.E.C. File Number.
  
  3(a)  Title of the Class of Securities To Be Sold
  
        Common Stock
  
  (b)   Name and Address of Each Broker Through Whom the Securities
        are to be Offered or Each Market Maker who is Acquiring the Securities
  
        E*Trade Financial
        4005 Windward Plaza Drive
        Alpharetta, GA  30005
  
  SEC USE ONLY
  
  Broker-Dealer File Number:
  
  (c)  Number of Shares or Other Units To Be Sold: 1,000
  
  (d)  Aggregate Market Value:  $13,330.00  (11/09/10)
  
  (e)  Number of Shares or Other Units Outstanding: 68,585,311
  
  (f)  Approximate Date of Sale: 11/11/2010
  
  (g)  Name of Each Securities Exchange: NASDAQ
  
  INSTRUCTIONS:
  
  1.	(a)	Name of issuer
  	(b)	Issuer's I.R.S. Identification Number
          (c)	Issuer's S.E.C. file number, if any
  	(d)	Issuer's address, including zip code
  	(e)	Issuer's telephone number, including area code
  
  2.	(a)	Name of person for whose account the securities are to be sold
  	(b)	Such person's relationship to the issuer (e.g., officer, director,
  10% stockholder, or member of immediate family of any of the foregoing)
  	(c)	Such person's address, including zip code
  
  3.	(a)	Title of the class of securities to be sold
  	(b)	Name and address of each broker through whom the securities
  are intended to be sold
  	(c)	Number of shares or other units to be sold (if debt securities,
  give the aggregate face amount)
  	(d)	Aggregate market value of the securities to be sold as of a
  specified date within 10 days prior to the filing of this notice
  	(e)	Number of shares or other units of the class outstanding,
  or if debt securities the face amount thereof outstanding, as shown by
  the most recent report or statement published by the issuer
  	(f)	Approximate date on which the securities are to be sold
  	(g)	Name of each securities exchange, if any, on which the securities
  are intended to be sold
  
  TABLE I - SECURITIES TO BE SOLD
  Furnish the following information with respect to the acquisition of the
  securities to be sold and with respect to the payment of all or any part
  of the purchase price or other consideration therefor:
  
  Title of the Class: Common Stock
  
  Date you Acquired: 05/14/10
  
  Nature of Acquisition Transaction: Acquired upon vesting of Restricted
  Stock Units  (Remark #1)
  
  Name of Person from Whom Acquired (if gift, also give date donor acquired):
  
      Issuer
  
  Amount of Securities Acquired: 1,000
  
  Date of Payment: (Remark #2)
  
  Nature of Payment: (Remark #2)
  
  INSTRUCTIONS:	If the securities were purchased and full payment therefor
  was not made in cash at the time of purchase, explain in the table or
  in a note thereto the nature of the consideration given.  If the
  consideration consisted of any note or other obligation, or if payment
  was made in installments describe the arrangement and state when the
  note or other obligation was discharged in full or the last installment
  paid.
  
  TABLE II - SECURITIES SOLD DURING THE PAST 3 MONTHS
  Furnish the following information with respect to the acquisition of the
  securities to be sold and with respect to the payment of all or any part
  of the purchase price or other consideration therefor:
  
  Name and Address of Seller:
  
    NONE
  
  Title of Securities Sold:
  
  Date of Sale:
  
  Amount of Securities Sold:
  
  Gross Proceeds:
  
  REMARKS:
  (1)Shares acquired are registered under a Registration Statement on Form S-8.
  (2)Shares acquired upon vesting of Restricted Stock Units awarded to reporting
  person as a director of the issuer and no payment was required by the Seller
  in connection therewith.
  
  INSTRUCTIONS: See the definition of "person" in paragraph (a) of Rule 144.
  Information is to be given not only as to the person for whose account
  the securities are to be sold but also as to all other persons included
  in that definition.  In addition, information shall be given as to sales
  by all persons whose sales are required by paragraph (e) of Rule 144
  to be aggregated with sales for the account of the person filing this
  notice.
  
  ATTENTION:  The person for whose account the securities to which this
  notice relates are to be sold hereby represents by signing this notice
  that he does not know any material adverse information in regard to the
  current and prospective operations of the Issuer of the securities to
  be sold which has not been publicly disclosed.  If each person has
  adopted a written trading plan or given trading instructions to satisfy
  Rule 10b5-1 under the Exchange Act, by singing the form and indicating
  the date that the plan was adopted or the instruction given, that person
  makes such representation as of the plan adoption or instruction date.
  
  DATE OF NOTICE:  November 10, 2010
  
  /s/ Hubert de Pesquidoux
  ____________________
  Hubert de Pesquidoux
  (SIGNATURE)
  
  DATE OF PLAN ADOPTION OR GIVING OF INSTRUCTION,
  IF RELYING ON RULE 10B5-1: September 2, 2010
  
  The notice shall be signed by the person for whose account the securities
  are to be sold.  At least one copy of the notice shall be manually signed.
  Any copies not manually signed shall bear typed or printed signatures.
  
  ATTENTION:  Intentional misstatements or omission of facts constitute
  Federal Criminal Violations (See 18 U.S.C. 1001)
  
  SM01DOCS\667695.1	SEC 1147 (08-07)
  	Potential persons who are to respond to the collection of information
  contained in this form are not required to respond unless the form displays a
  currently valid OMB control number.
  SM01DOCS667695.1											SEC 1147 (04-07)