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          <filerCredentials>
            <!-- Field: Pseudo-Tag; ID: Name; Data: Casdin Partners Master Fund, L.P. -->
            <cik>0001534265</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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      <issuerInfo>
        <issuerCik>0001287098</issuerCik>
        <issuerName>MAXCYTE, INC.</issuerName>
        <secFileNumber>001-40674</secFileNumber>
        <issuerAddress>
          <com:street1>9713 Key West Avenue, Suite 400</com:street1>
          <com:city>Rockville</com:city>
          <com:stateOrCountry>MD</com:stateOrCountry>
          <com:zipCode>20850</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>000-000-0000</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Casdin Partners Master Fund, L.P.</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Former 10% stockholder</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common Stock, par value $0.01 per share</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Stifel Nicolaus &amp; Company, Incorporated</name>
          <address>
            <com:street1>One Financial Plaza</com:street1>
            <com:street2>501 North Broadway</com:street2>
            <com:city>St. Louis</com:city>
            <com:stateOrCountry>MO</com:stateOrCountry>
            <com:zipCode>63102</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>5000</noOfUnitsSold>
        <aggregateMarketValue>28142.85</aggregateMarketValue>
        <noOfUnitsOutstanding>102046769</noOfUnitsOutstanding>
        <approxSaleDate>11/30/2022</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common Stock, par value $0.01 per share</securitiesClassTitle>
        <acquiredDate>08/27/2020</acquiredDate>
        <natureOfAcquisitionTransaction>Purchase</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>The shares were purchased in open market transactions.</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>5000</amountOfSecuritiesAcquired>
        <paymentDate>08/27/2020</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Casdin Partners Master Fund, L.P.</name>
          <address>
            <com:street1>1350 Avenue of the Americas, Suite 2600</com:street1>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10019</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Stock, par value $0.01 per share</securitiesClassTitle>
        <saleDate>11/29/2022</saleDate>
        <amountOfSecuritiesSold>10000</amountOfSecuritiesSold>
        <grossProceeds>58208.65</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Casdin Partners Master Fund, L.P.</name>
          <address>
            <com:street1>1350 Avenue of the Americas, Suite 2600</com:street1>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10019</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Stock, par value $0.01 per share</securitiesClassTitle>
        <saleDate>11/21/2022</saleDate>
        <amountOfSecuritiesSold>10000</amountOfSecuritiesSold>
        <grossProceeds>60412.60</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Casdin Partners Master Fund, L.P.</name>
          <address>
            <com:street1>1350 Avenue of the Americas, Suite 2600</com:street1>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10019</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Stock, par value $0.01 per share</securitiesClassTitle>
        <saleDate>11/18/2022</saleDate>
        <amountOfSecuritiesSold>5000</amountOfSecuritiesSold>
        <grossProceeds>31407.27</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Casdin Partners Master Fund, L.P.</name>
          <address>
            <com:street1>1350 Avenue of the Americas, Suite 2600</com:street1>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10019</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Stock, par value $0.01 per share</securitiesClassTitle>
        <saleDate>11/17/2022</saleDate>
        <amountOfSecuritiesSold>4800</amountOfSecuritiesSold>
        <grossProceeds>30374.33</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Casdin Partners Master Fund, L.P.</name>
          <address>
            <com:street1>1350 Avenue of the Americas, Suite 2600</com:street1>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10019</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Stock, par value $0.01 per share</securitiesClassTitle>
        <saleDate>11/16/2022</saleDate>
        <amountOfSecuritiesSold>25200</amountOfSecuritiesSold>
        <grossProceeds>168354.36</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Casdin Partners Master Fund, L.P.</name>
          <address>
            <com:street1>1350 Avenue of the Americas, Suite 2600</com:street1>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10019</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Stock, par value $0.01 per share</securitiesClassTitle>
        <saleDate>11/15/2022</saleDate>
        <amountOfSecuritiesSold>35000</amountOfSecuritiesSold>
        <grossProceeds>238112.51</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Casdin Partners Master Fund, L.P.</name>
          <address>
            <com:street1>1350 Avenue of the Americas, Suite 2600</com:street1>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10019</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Stock, par value $0.01 per share</securitiesClassTitle>
        <saleDate>11/09/2022</saleDate>
        <amountOfSecuritiesSold>175000</amountOfSecuritiesSold>
        <grossProceeds>1103532.50</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Casdin Partners Master Fund, L.P.</name>
          <address>
            <com:street1>1350 Avenue of the Americas, Suite 2600</com:street1>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10019</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Stock, par value $0.01 per share</securitiesClassTitle>
        <saleDate>11/08/2022</saleDate>
        <amountOfSecuritiesSold>175000</amountOfSecuritiesSold>
        <grossProceeds>1172517.50</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Casdin Partners Master Fund, L.P.</name>
          <address>
            <com:street1>1350 Avenue of the Americas, Suite 2600</com:street1>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10019</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Stock, par value $0.01 per share</securitiesClassTitle>
        <saleDate>10/03/2022</saleDate>
        <amountOfSecuritiesSold>735786</amountOfSecuritiesSold>
        <grossProceeds>4525083.90</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>11/30/2022</noticeDate>
        <signature>/s/ Eli Casdin</signature>
      </noticeSignature>
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text: 144
  0001534265
  XXXXXXXX
  LIVE
  0001287098
  MAXCYTE, INC.
  001-40674
  9713 Key West Avenue, Suite 400
  Rockville
  MD
  20850
  000-000-0000
  Casdin Partners Master Fund, L.P.
  Former 10% stockholder
  Common Stock, par value $0.01 per share
  Stifel Nicolaus & Company, Incorporated
  One Financial Plaza
  501 North Broadway
  St. Louis
  MO
  63102
  5000
  28142.85
  102046769
  11/30/2022
  NASDAQ
  Common Stock, par value $0.01 per share
  08/27/2020
  Purchase
  The shares were purchased in open market transactions.
  N
  5000
  08/27/2020
  Cash
  N
  Casdin Partners Master Fund, L.P.
  1350 Avenue of the Americas, Suite 2600
  New York
  NY
  10019
  Common Stock, par value $0.01 per share
  11/29/2022
  10000
  58208.65
  Casdin Partners Master Fund, L.P.
  1350 Avenue of the Americas, Suite 2600
  New York
  NY
  10019
  Common Stock, par value $0.01 per share
  11/21/2022
  10000
  60412.60
  Casdin Partners Master Fund, L.P.
  1350 Avenue of the Americas, Suite 2600
  New York
  NY
  10019
  Common Stock, par value $0.01 per share
  11/18/2022
  5000
  31407.27
  Casdin Partners Master Fund, L.P.
  1350 Avenue of the Americas, Suite 2600
  New York
  NY
  10019
  Common Stock, par value $0.01 per share
  11/17/2022
  4800
  30374.33
  Casdin Partners Master Fund, L.P.
  1350 Avenue of the Americas, Suite 2600
  New York
  NY
  10019
  Common Stock, par value $0.01 per share
  11/16/2022
  25200
  168354.36
  Casdin Partners Master Fund, L.P.
  1350 Avenue of the Americas, Suite 2600
  New York
  NY
  10019
  Common Stock, par value $0.01 per share
  11/15/2022
  35000
  238112.51
  Casdin Partners Master Fund, L.P.
  1350 Avenue of the Americas, Suite 2600
  New York
  NY
  10019
  Common Stock, par value $0.01 per share
  11/09/2022
  175000
  1103532.50
  Casdin Partners Master Fund, L.P.
  1350 Avenue of the Americas, Suite 2600
  New York
  NY
  10019
  Common Stock, par value $0.01 per share
  11/08/2022
  175000
  1172517.50
  Casdin Partners Master Fund, L.P.
  1350 Avenue of the Americas, Suite 2600
  New York
  NY
  10019
  Common Stock, par value $0.01 per share
  10/03/2022
  735786
  4525083.90
  11/30/2022
  /s/ Eli Casdin