content: <TABLE>
  <CAPTION>
  <S>     <C>    <C>    <C>    <C>    <C>    <C>
  
  
  
                                                                                                        OMB APPROVAL
  
                                                                                                        OMB Number: 3235-0101
                                                                                                        Expires: August 31,2003
                                                                                                        Estimated average burden
                                      UNITED STATES                                                     hours per response. . . 2.0
                         SECURITIES AND EXCHANGE COMMISSION
                                Washington, D.C. 20549                                                  SEC USE ONLY
                                                                                                        DOCUMENT SEQUENCE NO.
                                       FORM 144
                         NOTICE OF PROPOSED SALE OF SECURITIES                                          CUSIP NUMBER
                PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
                                                                                                        WORK LOCATION
  
  ATTENTION: Transmit for filing 3 copies of this form concurrently with either placing an order
             with a broker to execute sale or executing a sale directly with a market maker
  
  1(a)     NAME OF ISSUER   (Please type or print)                                         (b) IRS IDENT. NO.     (c) S.E.C. FILE NO.
           Enchira Biotechnology Corporation                                                   04-3078857             0-21130
  
   (d)     ADDRESS OF ISSUER  STREET   CITY  STATE  ZIP CODE                               (e) TELEPHONE
                                                                                          AREA CODE               NUMBERS
           4200 Research Forest Blvd.,                                                    281                     419-7000
           The Woodlands, TX, 77381
  
  
  2(a)    NAME OF PERSON FOR WHOSE                    (b) IRS IDENT.   (c) RELATIONSHIP TO    (d) ADDRESS STREET CITY  STATE  ZIP CODE
          ACCOUNT THE SECURITIES ARE TO BE SOLD           NO.              ISSUER
  
          MillenCo, L.P.                                  13-3532932       10% stockholder        666 5th Avenue, NY, NY 10103
  
  
  INSTRUCTION: The person filing this notice should contact the issuer to obtain the I.R.S. identification Number and
               the S.E.C. File Number.
  
  
  3(a) Title of    3(b)  Name and          SEC    (c) Number of     (d) Aggregate      (e) Number of    (f) Approx. Date  (g)Name of
       the Class        Address of         USE        Shares or         Market Value       Shares or        of Sale          Each
          of            Each Broker        ONLY       Other Units     See instr. 3(d)      Other Units      See instr.3(f)  Securities
       Securities       Through whom                  To Be Sold                          Outstanding       (MO. DAY YR.)   Exchange
       To Be Sold      the Securities               See instr. 3(c)                      See instr. 3(e)                    See instr.
                      Are To Be Offered                                                                                       3(g)
                       or Each Market     Broker-
                       Maker who is       Dealer
                       Acquiring the      File
                        Securities        Number
  
      Common Stock    Charles Schwab &
                      Co.
                      101 Montgomery St.
                      San Francisco,                 91,278                $31,035          9,127,890           3/21/02         N/A
                      CA 94104
  
                      Knight Securities
                      525 Washington Blvd.
                      Jersey City,
                      NJ 07310
  
                      Spear, Leeds &
                      Kellogg
                      120 Broadway
                      NY, NY 10271
  
                      Herzog, Heine, Geduld
                      525 Washington Blvd.
                      Jersey City, NJ 07310
  
  
  <PAGE>
  
  INSTRUCTIONS:
  1.   (a)  Name of issuer
       (b)  Issuer's I.R.S. Identification Number
       (c)  Issuer's S.E.C. file number, if any
       (d)  Issuer's address, including zip code
       (e)  Issuers's telephone number, including area code
  
  2.   (a)  Name of person for whose account the securities are to be sold
       (b)  Such person's I.R.S. identification number, if such person is an entity
       (c)  Such person's relationship to the issuer (e.g., officer, director, 10% stockholder, or member of immediate
            family of any of the foregoing)
       (d)  Such person's address, including zip code
  
  3.   (a)  Title of the class of securities to be sold
       (b)  Name and Address of each broker through whom the securities are
            intended to be sold
       (c)  Number of shares or other units to be sold (if debt securities, give
            the aggregate face amount) (d) Aggregate market value of the
            securities to be sold as of a specified date within 10 days prior to
            the filing of this notice
       (e)  Number of shares or other units of the class outstanding, or if debt
            securities the face amount thereof outstanding, as shown by the most
            recent report or statement published by the issuer
       (f)  Approximate date on which the securities are to be sold
       (g)  Name of each securities exchange, if any, on which the securities are intended to be sold
  
  
  
  <PAGE>
  
                          TABLE I -- SECURITIES TO BE SOLD
                   Furnish the following information with respect
                to the acquisition of the securities to be sold and
               with respect to the payment of all or any part of the
                  purchase price or other consideration therefor:
  
                                                            Name of Person from Whom
                                                                  Acquired
    Title of        Date you           Nature of            (if gift, also give date    Amount of Securities     Date of    Nature of
    the Class       Acquired       Acquisition Transaction       donor acquired)              Acquired           Payment     Payment
  
  *Series B
   Preferred Stock   2/26/97          Purchase                    Issuer               41,000 shares of          2/26/97     Cash
                                                                                       Series B Preferred Stock
  
  INSTRUCTIONS:
  1.   If the securities were purchased and full payment therefor was not made in
       cash at the time of purchase, explain in the table or in a note thereto the
       nature of the consideration given. If the consideration consisted of any
       note or other obligation, or if payment was made in installments describe
       the arrangement and state when the note or other obligation was discharged
       in full or the last installment paid.
  
  2.   If within two years after the acquisition of the securities the person for
       whose account they are to be sold had any short positions, put or other
       option to dispose of securities referred to in paragraph (d)(3) of Rule
       144, furnish full information with respect thereto.
  
  
  
  <PAGE>
  
                   TABLE II -- SECURITIES SOLD DURING THE PAST 3 MONTHS
                     Furnish the following information as to all  securities of
                  the issuer sold during the past 3 months by the person for
                         whose account the securities are to be sold.
  
  
    Name and Address      Title of                                Amount of
    of Seller          Securities Sold      Date of Sale          Securities Sold          Gross Proceeds
  
  Millenco, L.P.       Common Stock     See Attached Schedule    See Attached Schedule    See Attached Schedule
  666 5th Avenue
  NY, NY 10103
  
  
  REMARKS: *Filer received shares of common stock to be sold upon issuer's
  mandatory redemption of filer's Series B Preferred Stock effective as of
  February 26, 2002.
  
  
  
  INSTRUCTIONS:  See the definition of "person" in paragraph (a) of Rule 144.
  Information  is to be given  not only as to the  person  for whose  account  the
  seucrities  are to be sold but also as to all  other  persons  included  in that
  definition.  In addition,  information shall be given as to sales by all persons
  whose sales are  required by  paragraph  (c) of Rule 144 to be  aggregated  with
  sales for the account of the person filing this notice.
  
  
  ATTENTION: The person for whose account the securities to which this notice
  relates are to be sold hereby represents by signing this notice that he does not
  know any material  adverse  information in regard to the current and prospective
  operations  of the  Issuer  of the  securities  to be sold  which  has not  been
  publicly disclosed.
  
  
  
  
                                                 MILLENCO, L.P.
  3/22/02                                    By: Millennium Management L.L.C.,
  DATE OF NOTICE                                 as general partner
  
  
  
                                                  By: /s/ Terry Feeney
                                                      -------------------------
                                                      Terry Feeney
                                                      Chief Operating Officer
                                                      (SIGNATURE)
  
  
  
  The notice shall be signed by the person for whose account the securites are to
         be sold. At least one copy of the notice shall be manually signed.
        Any copies not manually signed shall bear typed or printed signatures
  
  
                                     ATTENTION:
             Intentional misstatements or omission of facts constitute
                  Federal Criminal Violations (See 18 U.S.C. 1001)
  
  
  
  
  
  
  
  
  http://www.sec.gov/divisions/corpfin/forms/144.htm
  Last update: 009/01/2000
  </TABLE>
  <PAGE>
  <TABLE>
  <CAPTION>
  
                Table II - SECURITIES SOLD DURING PAST THREE MONTHS
  
  
  <S>                      <C>                    <C>
                         Amount of
    Date of              ecurities
     Sale               S  Sold              Gross Proceeds
     1/4/02              (39,000)                25,349.61
     1/7/02               (8,800)                 5,807.91
     1/8/02              (37,000)                21,829.67
    2/11/02               (1,000)                   400.00
    2/11/02               (2,000)                   800.00
    2/12/02                 (100)                    39.00
    2/12/02                 (100)                    37.00
    2/12/02                 (400)                   148.00
    2/12/02                 (500)                   185.00
    2/12/02                 (700)                   252.00
    2/12/02                 (900)                   333.00
    2/12/02               (1,000)                   360.00
    2/12/02               (2,400)                   840.00
    2/12/02               (3,000)                 1,110.00
    2/12/02               (5,000)                 1,850.00
    2/12/02               (5,900)                 2,124.00
    2/12/02              (17,000)                 5,949.91
  
  </TABLE>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "form144.txt", "description": "ENCHIRA BIOTECH", "secsgml_size_bytes": 11361}]
text: OMB APPROVAL
  
                                                                                                        OMB Number: 3235-0101
                                                                                                        Expires: August 31,2003
                                                                                                        Estimated average burden
                                      UNITED STATES                                                     hours per response. . . 2.0
                         SECURITIES AND EXCHANGE COMMISSION
                                Washington, D.C. 20549                                                  SEC USE ONLY
                                                                                                        DOCUMENT SEQUENCE NO.
                                       FORM 144
                         NOTICE OF PROPOSED SALE OF SECURITIES                                          CUSIP NUMBER
                PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
                                                                                                        WORK LOCATION
  
  ATTENTION: Transmit for filing 3 copies of this form concurrently with either placing an order
             with a broker to execute sale or executing a sale directly with a market maker
  
  1(a)     NAME OF ISSUER   (Please type or print)                                         (b) IRS IDENT. NO.     (c) S.E.C. FILE NO.
           Enchira Biotechnology Corporation                                                   04-3078857             0-21130
  
   (d)     ADDRESS OF ISSUER  STREET   CITY  STATE  ZIP CODE                               (e) TELEPHONE
                                                                                          AREA CODE               NUMBERS
           4200 Research Forest Blvd.,                                                    281                     419-7000
           The Woodlands, TX, 77381
  
  2(a)    NAME OF PERSON FOR WHOSE                    (b) IRS IDENT.   (c) RELATIONSHIP TO    (d) ADDRESS STREET CITY  STATE  ZIP CODE
          ACCOUNT THE SECURITIES ARE TO BE SOLD           NO.              ISSUER
  
          MillenCo, L.P.                                  13-3532932       10% stockholder        666 5th Avenue, NY, NY 10103
  
  INSTRUCTION: The person filing this notice should contact the issuer to obtain the I.R.S. identification Number and
               the S.E.C. File Number.
  
  3(a) Title of    3(b)  Name and          SEC    (c) Number of     (d) Aggregate      (e) Number of    (f) Approx. Date  (g)Name of
       the Class        Address of         USE        Shares or         Market Value       Shares or        of Sale          Each
          of            Each Broker        ONLY       Other Units     See instr. 3(d)      Other Units      See instr.3(f)  Securities
       Securities       Through whom                  To Be Sold                          Outstanding       (MO. DAY YR.)   Exchange
       To Be Sold      the Securities               See instr. 3(c)                      See instr. 3(e)                    See instr.
                      Are To Be Offered                                                                                       3(g)
                       or Each Market     Broker-
                       Maker who is       Dealer
                       Acquiring the      File
                        Securities        Number
  
      Common Stock    Charles Schwab &
                      Co.
                      101 Montgomery St.
                      San Francisco,                 91,278                $31,035          9,127,890           3/21/02         N/A
                      CA 94104
  
                      Knight Securities
                      525 Washington Blvd.
                      Jersey City,
                      NJ 07310
  
                      Spear, Leeds &
                      Kellogg
                      120 Broadway
                      NY, NY 10271
  
                      Herzog, Heine, Geduld
                      525 Washington Blvd.
                      Jersey City, NJ 07310
  INSTRUCTIONS:
  1.   (a)  Name of issuer
       (b)  Issuer's I.R.S. Identification Number
       (c)  Issuer's S.E.C. file number, if any
       (d)  Issuer's address, including zip code
       (e)  Issuers's telephone number, including area code
  
  2.   (a)  Name of person for whose account the securities are to be sold
       (b)  Such person's I.R.S. identification number, if such person is an entity
       (c)  Such person's relationship to the issuer (e.g., officer, director, 10% stockholder, or member of immediate
            family of any of the foregoing)
       (d)  Such person's address, including zip code
  
  3.   (a)  Title of the class of securities to be sold
       (b)  Name and Address of each broker through whom the securities are
            intended to be sold
       (c)  Number of shares or other units to be sold (if debt securities, give
            the aggregate face amount) (d) Aggregate market value of the
            securities to be sold as of a specified date within 10 days prior to
            the filing of this notice
       (e)  Number of shares or other units of the class outstanding, or if debt
            securities the face amount thereof outstanding, as shown by the most
            recent report or statement published by the issuer
       (f)  Approximate date on which the securities are to be sold
       (g)  Name of each securities exchange, if any, on which the securities are intended to be sold
  TABLE I -- SECURITIES TO BE SOLD
                   Furnish the following information with respect
                to the acquisition of the securities to be sold and
               with respect to the payment of all or any part of the
                  purchase price or other consideration therefor:
  
                                                            Name of Person from Whom
                                                                  Acquired
    Title of        Date you           Nature of            (if gift, also give date    Amount of Securities     Date of    Nature of
    the Class       Acquired       Acquisition Transaction       donor acquired)              Acquired           Payment     Payment
  
  *Series B
   Preferred Stock   2/26/97          Purchase                    Issuer               41,000 shares of          2/26/97     Cash
                                                                                       Series B Preferred Stock
  
  INSTRUCTIONS:
  1.   If the securities were purchased and full payment therefor was not made in
       cash at the time of purchase, explain in the table or in a note thereto the
       nature of the consideration given. If the consideration consisted of any
       note or other obligation, or if payment was made in installments describe
       the arrangement and state when the note or other obligation was discharged
       in full or the last installment paid.
  
  2.   If within two years after the acquisition of the securities the person for
       whose account they are to be sold had any short positions, put or other
       option to dispose of securities referred to in paragraph (d)(3) of Rule
       144, furnish full information with respect thereto.
  TABLE II -- SECURITIES SOLD DURING THE PAST 3 MONTHS
                     Furnish the following information as to all  securities of
                  the issuer sold during the past 3 months by the person for
                         whose account the securities are to be sold.
  
    Name and Address      Title of                                Amount of
    of Seller          Securities Sold      Date of Sale          Securities Sold          Gross Proceeds
  
  Millenco, L.P.       Common Stock     See Attached Schedule    See Attached Schedule    See Attached Schedule
  666 5th Avenue
  NY, NY 10103
  
  REMARKS: *Filer received shares of common stock to be sold upon issuer's
  mandatory redemption of filer's Series B Preferred Stock effective as of
  February 26, 2002.
  
  INSTRUCTIONS:  See the definition of "person" in paragraph (a) of Rule 144.
  Information  is to be given  not only as to the  person  for whose  account  the
  seucrities  are to be sold but also as to all  other  persons  included  in that
  definition.  In addition,  information shall be given as to sales by all persons
  whose sales are  required by  paragraph  (c) of Rule 144 to be  aggregated  with
  sales for the account of the person filing this notice.
  
  ATTENTION: The person for whose account the securities to which this notice
  relates are to be sold hereby represents by signing this notice that he does not
  know any material  adverse  information in regard to the current and prospective
  operations  of the  Issuer  of the  securities  to be sold  which  has not  been
  publicly disclosed.
  
                                                 MILLENCO, L.P.
  3/22/02                                    By: Millennium Management L.L.C.,
  DATE OF NOTICE                                 as general partner
  
                                                  By: /s/ Terry Feeney
                                                      -------------------------
                                                      Terry Feeney
                                                      Chief Operating Officer
                                                      (SIGNATURE)
  
  The notice shall be signed by the person for whose account the securites are to
         be sold. At least one copy of the notice shall be manually signed.
        Any copies not manually signed shall bear typed or printed signatures
  
                                     ATTENTION:
             Intentional misstatements or omission of facts constitute
                  Federal Criminal Violations (See 18 U.S.C. 1001)
  
  http://www.sec.gov/divisions/corpfin/forms/144.htm
  Last update: 009/01/2000
  Table II - SECURITIES SOLD DURING PAST THREE MONTHS
  Amount of
    Date of              ecurities
     Sale               S  Sold              Gross Proceeds
     1/4/02              (39,000)                25,349.61
     1/7/02               (8,800)                 5,807.91
     1/8/02              (37,000)                21,829.67
    2/11/02               (1,000)                   400.00
    2/11/02               (2,000)                   800.00
    2/12/02                 (100)                    39.00
    2/12/02                 (100)                    37.00
    2/12/02                 (400)                   148.00
    2/12/02                 (500)                   185.00
    2/12/02                 (700)                   252.00
    2/12/02                 (900)                   333.00
    2/12/02               (1,000)                   360.00
    2/12/02               (2,400)                   840.00
    2/12/02               (3,000)                 1,110.00
    2/12/02               (5,000)                 1,850.00
    2/12/02               (5,900)                 2,124.00
    2/12/02              (17,000)                 5,949.91