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  <issuerName>CASI Pharmaceuticals, INc.</issuerName>
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  <issuerAddress>
  <street1 xmlns="http://www.sec.gov/edgar/common">1701-1702, CHINA CENTRAL OFFICE TOWER 1</street1>
  <street2 xmlns="http://www.sec.gov/edgar/common">NO. 81 JIANGUO ROAD, CHAOYANG DISTRICT</street2>
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  <issuerContactPhone>86 10-6561 8789</issuerContactPhone>
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  <city xmlns="http://www.sec.gov/edgar/common">New York</city>
  <stateOrCountry xmlns="http://www.sec.gov/edgar/common">NY</stateOrCountry>
  <zipCode xmlns="http://www.sec.gov/edgar/common">10022</zipCode>
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  <securitiesExchangeName>NASDAQ</securitiesExchangeName>
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  <isGiftTransaction>N</isGiftTransaction>
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  <paymentDate>09/08/2022</paymentDate>
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  <name>Panacea Innovation Ltd.</name>
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  <street1 xmlns="http://www.sec.gov/edgar/common">C/O PANACEA VENTURE, NO. 5, LANE 1350</street1>
  <street2 xmlns="http://www.sec.gov/edgar/common">FUXING MIDDLE ROAD</street2>
  <city xmlns="http://www.sec.gov/edgar/common">SHANGHAI</city>
  <stateOrCountry xmlns="http://www.sec.gov/edgar/common">F4</stateOrCountry>
  <zipCode xmlns="http://www.sec.gov/edgar/common">200031</zipCode>
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  <saleDate>03/05/2024</saleDate>
  <amountOfSecuritiesSold>134000</amountOfSecuritiesSold>
  <grossProceeds>925940.00</grossProceeds>
  </securitiesSoldInPast3Months>
  <noticeSignature>
  <noticeDate>03/15/2024</noticeDate>
  <signature>/s/ James Huang</signature>
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text: 144
  0002010692
  XXXXXXXX
  LIVE
  0001962738
  CASI Pharmaceuticals, INc.
  001-41666
  1701-1702, CHINA CENTRAL OFFICE TOWER 1
  NO. 81 JIANGUO ROAD, CHAOYANG DISTRICT
  BEIJING
  F4
  100025
  86 10-6561 8789
  Panacea Innovation Ltd
  Owner
  Ordinary Shares
  Cantor Fitzgerald
  110 East 59th Street
  New York
  NY
  10022
  171000
  534186.90
  13378175
  03/15/2024
  NASDAQ
  Ordinary Shares
  09/08/2022
  Open Market Purchase
  Open Market Purchase
  N
  371517
  09/08/2022
  Cash
  N
  Panacea Innovation Ltd.
  C/O PANACEA VENTURE, NO. 5, LANE 1350
  FUXING MIDDLE ROAD
  SHANGHAI
  F4
  200031
  Ordinary Shares
  03/05/2024
  134000
  925940.00
  03/15/2024
  /s/ James Huang