content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:xsd="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <headerData>
  <submissionType>144</submissionType>
  <filerInfo>
  <filer>
  <filerCredentials>
  <cik>0001918894</cik>
  <ccc>XXXXXXXX</ccc>
  </filerCredentials>
  </filer>
  <liveTestFlag>LIVE</liveTestFlag>
  </filerInfo>
  </headerData>
  <formData>
  <issuerInfo>
  <issuerCik>0001571949</issuerCik>
  <issuerName>Intercontinental Exchange, Inc.</issuerName>
  <secFileNumber>001-36198</secFileNumber>
  <issuerAddress>
  <street1 xmlns="http://www.sec.gov/edgar/common">5660 New Northside Drive</street1>
  <city xmlns="http://www.sec.gov/edgar/common">Atlanta</city>
  <stateOrCountry xmlns="http://www.sec.gov/edgar/common">GA</stateOrCountry>
  <zipCode xmlns="http://www.sec.gov/edgar/common">30328</zipCode>
  </issuerAddress>
  <issuerContactPhone>770-857-4700</issuerContactPhone>
  <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Foley Douglas </nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
  <relationshipsToIssuer>
  <relationshipToIssuer>Officer</relationshipToIssuer>
  </relationshipsToIssuer>
  </issuerInfo>
  <securitiesInformation>
  <securitiesClassTitle>Common</securitiesClassTitle>
  <brokerOrMarketmakerDetails>
  <name>Morgan Stanley Smith Barney LLC Executive Services Services</name>
  <address>
  <street1 xmlns="http://www.sec.gov/edgar/common">200 W Civic Center Drive</street1>
  <street2 xmlns="http://www.sec.gov/edgar/common">4th Floor</street2>
  <city xmlns="http://www.sec.gov/edgar/common">Sandy</city>
  <stateOrCountry xmlns="http://www.sec.gov/edgar/common">UT</stateOrCountry>
  <zipCode xmlns="http://www.sec.gov/edgar/common">84070</zipCode>
  </address>
  </brokerOrMarketmakerDetails>
  <noOfUnitsSold>8259</noOfUnitsSold>
  <aggregateMarketValue>1484555.25</aggregateMarketValue>
  <noOfUnitsOutstanding>573626271</noOfUnitsOutstanding>
  <approxSaleDate>05/30/2025</approxSaleDate>
  <securitiesExchangeName>NYSE</securitiesExchangeName>
  </securitiesInformation>
  <securitiesToBeSold>
  <securitiesClassTitle>Common</securitiesClassTitle>
  <acquiredDate>05/30/2025</acquiredDate>
  <natureOfAcquisitionTransaction>Exercise of Stock Options</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>8259</amountOfSecuritiesAcquired>
  <paymentDate>05/30/2025</paymentDate>
  <natureOfPayment>Cash</natureOfPayment>
  </securitiesToBeSold>
  <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
  <securitiesSoldInPast3Months>
  <sellerDetails>
  <name>10b5-1 Sales for DOUGLAS FOLEY</name>
  <address>
  <street1 xmlns="http://www.sec.gov/edgar/common">5660 New Northside Drive</street1>
  <city xmlns="http://www.sec.gov/edgar/common">Atlanta</city>
  <stateOrCountry xmlns="http://www.sec.gov/edgar/common">GA</stateOrCountry>
  <zipCode xmlns="http://www.sec.gov/edgar/common">30328</zipCode>
  </address>
  </sellerDetails>
  <securitiesClassTitle>Common</securitiesClassTitle>
  <saleDate>03/12/2025</saleDate>
  <amountOfSecuritiesSold>1600</amountOfSecuritiesSold>
  <grossProceeds>270624</grossProceeds>
  </securitiesSoldInPast3Months>
  <noticeSignature>
  <noticeDate>06/03/2025</noticeDate>
  <signature>/s/ Douglas Foley</signature>
  </noticeSignature>
  </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 3381}]
text: 144
  0001918894
  XXXXXXXX
  LIVE
  0001571949
  Intercontinental Exchange, Inc.
  001-36198
  5660 New Northside Drive
  Atlanta
  GA
  30328
  770-857-4700
  Foley Douglas
  Officer
  Common
  Morgan Stanley Smith Barney LLC Executive Services Services
  200 W Civic Center Drive
  4th Floor
  Sandy
  UT
  84070
  8259
  1484555.25
  573626271
  05/30/2025
  NYSE
  Common
  05/30/2025
  Exercise of Stock Options
  Issuer
  N
  8259
  05/30/2025
  Cash
  N
  10b5-1 Sales for DOUGLAS FOLEY
  5660 New Northside Drive
  Atlanta
  GA
  30328
  Common
  03/12/2025
  1600
  270624
  06/03/2025
  /s/ Douglas Foley