content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001582090</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001665918</issuerCik>
        <issuerName>US Foods Holding Corp.</issuerName>
        <secFileNumber>001-37786</secFileNumber>
        <issuerAddress>
          <com:street1>9399 W. HIGGINS RD.</com:street1>
          <com:street2>SUITE 100</com:street2>
          <com:city>ROSEMONT</com:city>
          <com:stateOrCountry>IL</com:stateOrCountry>
          <com:zipCode>60018</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>8477208000</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Sachem Head Capital Management LP</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Director</relationshipToIssuer>
          <relationshipToIssuer>Affiliate of Director</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Goldman Sachs &amp; Co. LLC</name>
          <address>
            <com:street1>200 West Street</com:street1>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10282</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>3000000</noOfUnitsSold>
        <aggregateMarketValue>133920000.00</aggregateMarketValue>
        <noOfUnitsOutstanding>245851550</noOfUnitsOutstanding>
        <approxSaleDate>12/11/2023</approxSaleDate>
        <securitiesExchangeName>NYSE</securitiesExchangeName>
      </securitiesInformation>
      <securitiesInformation>
        <securitiesClassTitle>Common Stock (underlying Call Options)</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Goldman Sachs &amp; Co. LLC</name>
          <address>
            <com:street1>200 West Street</com:street1>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10282</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>50000</noOfUnitsSold>
        <aggregateMarketValue>2232000.00</aggregateMarketValue>
        <noOfUnitsOutstanding>245851550</noOfUnitsOutstanding>
        <approxSaleDate>12/11/2023</approxSaleDate>
        <securitiesExchangeName>other</securitiesExchangeName>
      </securitiesInformation>
      <securitiesInformation>
        <securitiesClassTitle>Common Stock (underlying Call Options)</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Goldman Sachs &amp; Co. LLC</name>
          <address>
            <com:street1>200 West Street</com:street1>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10282</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>200000</noOfUnitsSold>
        <aggregateMarketValue>8928000.00</aggregateMarketValue>
        <noOfUnitsOutstanding>245851550</noOfUnitsOutstanding>
        <approxSaleDate>12/11/2023</approxSaleDate>
        <securitiesExchangeName>other</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <acquiredDate>11/30/2021</acquiredDate>
        <natureOfAcquisitionTransaction>Open Market Purchases</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>N/A</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>3000000</amountOfSecuritiesAcquired>
        <paymentDate>11/30/2021</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common Stock (underlying Call Options)</securitiesClassTitle>
        <acquiredDate>05/17/2021</acquiredDate>
        <natureOfAcquisitionTransaction>via Broker</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Goldman Sachs &amp; Co. LLC</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>50000</amountOfSecuritiesAcquired>
        <paymentDate>05/17/2021</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common Stock (underlying Call Options)</securitiesClassTitle>
        <acquiredDate>05/18/2021</acquiredDate>
        <natureOfAcquisitionTransaction>via Broker</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Goldman Sachs &amp; Co.</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>200000</amountOfSecuritiesAcquired>
        <paymentDate>05/18/2021</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <remarks>Sachem Head Capital Management LP (SHCM) is the investment manager of certain funds that are selling the shares. Scott Ferguson, the founder and managing partner of SHCM, is a director of the Issuer. The aggregate market value is as of the close of business on 12/08/2023. The number of securities outstanding is as of 11/03/2023. The shares proposed to be sold were acquired and paid for between 11/30/2021 and 02/11/2022. The call options to be sold reference 50,000 shares with a $40.00 strike price and expiration date of 12/15/2023 and 200,000 shares with a $50.00 strike price and expiration date of 12/15/2023.</remarks>
      <noticeSignature>
        <noticeDate>12/11/2023</noticeDate>
        <signature>/s/ Michael D. Adamski, as General Counsel</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 6205}]
text: 144
  0001582090
  XXXXXXXX
  LIVE
  0001665918
  US Foods Holding Corp.
  001-37786
  9399 W. HIGGINS RD.
  SUITE 100
  ROSEMONT
  IL
  60018
  8477208000
  Sachem Head Capital Management LP
  Director
  Affiliate of Director
  Common Stock
  Goldman Sachs & Co. LLC
  200 West Street
  New York
  NY
  10282
  3000000
  133920000.00
  245851550
  12/11/2023
  NYSE
  Common Stock (underlying Call Options)
  Goldman Sachs & Co. LLC
  200 West Street
  New York
  NY
  10282
  50000
  2232000.00
  245851550
  12/11/2023
  other
  Common Stock (underlying Call Options)
  Goldman Sachs & Co. LLC
  200 West Street
  New York
  NY
  10282
  200000
  8928000.00
  245851550
  12/11/2023
  other
  Common Stock
  11/30/2021
  Open Market Purchases
  N/A
  N
  3000000
  11/30/2021
  Cash
  Common Stock (underlying Call Options)
  05/17/2021
  via Broker
  Goldman Sachs & Co. LLC
  N
  50000
  05/17/2021
  Cash
  Common Stock (underlying Call Options)
  05/18/2021
  via Broker
  Goldman Sachs & Co.
  N
  200000
  05/18/2021
  Cash
  Y
  Sachem Head Capital Management LP (SHCM) is the investment manager of certain funds that are selling the shares. Scott Ferguson, the founder and managing partner of SHCM, is a director of the Issuer. The aggregate market value is as of the close of business on 12/08/2023. The number of securities outstanding is as of 11/03/2023. The shares proposed to be sold were acquired and paid for between 11/30/2021 and 02/11/2022. The call options to be sold reference 50,000 shares with a $40.00 strike price and expiration date of 12/15/2023 and 200,000 shares with a $50.00 strike price and expiration date of 12/15/2023.
  12/11/2023
  /s/ Michael D. Adamski, as General Counsel