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  <P> <TABLE align="right" width="30%" border="1" cellspacing="0" cellpadding="1" bgcolor="#eeeeee"> <TR><TD align="center" nowrap><FONT size="2">OMB APPROVAL</FONT></TD></TR> <TR><TD nowrap><FONT size="2">OMB Number: 3235-0101</FONT></TD></TR> <TR><TD nowrap><FONT size="2">Expires: December 31, 2006</FONT></TD></TR> <TR><TD nowrap><FONT size="2">Estimated average burden<BR> hours per response...4.47</FONT></TD></TR></TABLE>
  <BR clear="right"> <P>&nbsp;  <TABLE align="right" width="30%" border="1" cellpadding="1" cellspacing="0" bgcolor="#eeeeee"> <TR><TD align="center" nowrap><FONT size="2">SEC USE ONLY</FONT></TD></TR> <TR><TD nowrap><FONT size="2">DOCUMENT SEQUENCE NO.</FONT></TD></TR> <TR><TD nowrap><FONT size="2">CUSIP NUMBER</FONT></TD></TR> <TR><TD nowrap><FONT size="2">WORK LOCATION</FONT></TD></TR> </TABLE>
  <BR clear="right">  <P align="center"><FONT size="3"><B>UNITED STATES<BR>SECURITIES AND EXCHANGE COMMISSION</B></FONT><BR> <FONT size="2"><B>Washington, DC 20549</B></FONT> <P align="center"><FONT size="4"><B>FORM 144</B></FONT> <P align="center"><FONT size="3"><B>NOTICE OF PROPOSED SALE OF SECURITIES<BR> PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933</B></FONT>
  <TABLE border="0" width="100%" cellspacing="0"> <TR valign="bottom"> <TD width="10%">&nbsp;</TD> <TD width="3%">&nbsp;</TD> <TD width="87%">&nbsp;</TD> </TR> <TR valign="top"> <TD><FONT size="2"><B>ATTENTION:</B></FONT></TD> <TD>&nbsp;</TD> <TD><FONT size="2"><I>Transmit for filing 3 copies of  this form concurrently with either placing an order with a broker to  execute sale or executing a sale directly with a market maker.</I></FONT></TD> </TR> </TABLE>
  <HR size="2" noshade>  <TABLE border="0" width="100%" cellpadding="2" cellspacing="0"> <TR valign="top"> <TD width="4%" nowrap><FONT size="2"><B>1(a)</B></FONT></TD> <TD width="35%"><FONT size="2"><B>Name of Issuer</B></FONT></TD> <TD width="2%"><FONT size="2">&nbsp;</FONT></TD> <TD width="3%"><FONT size="2"><B>(b)</B></FONT></TD> <TD width="30%"><FONT size="2"><B>IRS Ident. No.</B></FONT></TD> <TD width="2%"><FONT size="2">&nbsp;</FONT></TD> <TD width="3%"><FONT size="2"><B>(c)</B></FONT></TD> <TD width="2
  5%"><FONT size="2"><B>S.E.C. File No.</B></FONT></TD> </TR>
  <TR> <TD colspan="8"><FONT size="2">&nbsp;</FONT></TD> </TR>
  <TR valign="bottom"> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">
  INTERMUNE, INC.
  </FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">
  94-3296648
  </FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">
  0-29801
  </FONT></TD> </TR>  <TR valign="top"> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><HR size="1" noshade></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><HR size="1" noshade></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><HR size="1" noshade></TD> </TR>
  <TR> <TD colspan="8"><FONT size="2">&nbsp;</FONT></TD> </TR>
  <TR valign="top"> <TD><FONT size="2"><B>(d)</B></FONT></TD> <TD><FONT size="2"><B>Address of Issuer</B></FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2"><B>(e)</B></FONT></TD> <TD><FONT size="2"><B>Telephone</B></FONT></TD> </TR>
  <TR> <TD colspan="8"><FONT size="2">&nbsp;</FONT></TD> </TR>
  <TR valign="bottom"> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">
  3280 Bayshore Boulevard
  <BR>
  
  </FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">
  Brisbane
  ,&nbsp;
  CA
  &nbsp;&nbsp;
  94005
  </FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">
  415
  &nbsp;
  466-2200
  </FONT></TD> </TR>  <TR> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><HR size="1" noshade></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><HR size="1" noshade></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><HR size="1" noshade></TD> </TR>
  <TR valign="top"> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">(Street)</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">(City)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(State)&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;(Zip Code)</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">(Area Code)&nbsp;&nbsp;&nbsp;(Number)</FONT></TD> </TR>
  <TR> <TD colspan="8"><FONT size="2">&nbsp;</FONT></TD> </TR>  <TR valign="top"> <TD><FONT size="2"><B>2(a)</B></FONT></TD> <TD><FONT size="2"><B>Name of Person For Whose Account the<BR>Securities are to be Sold</B></FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2"><B>(b)</B></FONT></TD> <TD><FONT size="2"><B>IRS Ident. No.</B></FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2"><B>(c)</B></FONT></TD> <TD><FONT size="2"><B>Relationship to Issuer</B></FONT></TD> </TR>
  <TR> <TD colspan="8"><FONT size="2">&nbsp;</FONT></TD> </TR>
  <TR valign="bottom"> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">
  Howard Allan Simon
  </FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">
  
  </FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">
  Officer
  </FONT></TD> </TR>  <TR> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><HR size="1" noshade></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><HR size="1" noshade></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><HR size="1" noshade></TD> </TR>
  <TR> <TD colspan="8"><FONT size="2">&nbsp;</FONT></TD> </TR>
  <TR valign="top"> <TD><FONT size="2"><B>(d)</B></FONT></TD> <TD><FONT size="2"><B>Address</B></FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> </TR>
  <TR> <TD colspan="8"><FONT size="2">&nbsp;</FONT></TD> </TR>
  <TR valign="bottom"> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">
  3280 Bayshore Boulevard
  <BR>
  
  </FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">
  Brisbane
  ,&nbsp;
  CA
  &nbsp;&nbsp;
  94005
  </FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2"></FONT></TD> </TR>
  <TR> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><HR size="1" noshade></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><HR size="1" noshade></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> </TR>
  <TR valign="top"> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">(Street)</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">(City)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(State)&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;(Zip Code)</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> <TD><FONT size="2">&nbsp;</FONT></TD> </TR> </TABLE>
  <HR size="2" noshade>  <TABLE border="0" width="100%"> <TR valign="top"> <TD width="10%"><FONT size="2"><B>INSTRUCTION:</B></FONT></TD> <TD width="3%">&nbsp;</TD> <TD width="87%"><FONT size="2"><i>The person filing this notice should contact  the issuer to obtain the I.R.S. Identification Number and the S.E.C. File Number</i></FONT></TD> </TR> </TABLE>
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  <P><HR noshade><P>
  <H5 align="left" style="page-break-before:always">&nbsp;</H5><P>
  <HR size="2" noshade> <TABLE border="0" width="100%" cellspacing="0" cellpadding="2"> <TR valign="bottom">  <TD width="10%"><FONT size="1">&nbsp;</FONT></TD> <TD width="1%"><FONT size="1">&nbsp;</FONT></TD> <TD width="20%"><FONT size="1">&nbsp;</FONT></TD> <TD width="10%"><FONT size="1">&nbsp;</FONT></TD> <TD width="1%"><FONT size="1">&nbsp;</FONT></TD> <TD width="1%"><FONT size="1">&nbsp;</FONT></TD> <TD width="1%"><FONT size="1">&nbsp;</FONT></TD>
  <TD width="1%"><FONT size="1">&nbsp;</FONT></TD> <TD width="1%"><FONT size="1">&nbsp;</FONT></TD> <TD width="1%"><FONT size="1">&nbsp;</FONT></TD> <TD width="1%"><FONT size="1">&nbsp;</FONT></TD> <TD width="1%"><FONT size="1">&nbsp;</FONT></TD> <TD width="1%"><FONT size="1">&nbsp;</FONT></TD> <TD width="12%"><FONT size="1">&nbsp;</FONT></TD> <TD width="1%"><FONT size="1">&nbsp;</FONT></TD> <TD width="10%"><FONT size="1">&nbsp;</FONT></TD> </TR>
  <TR valign="bottom">  <TD align="center"><FONT size="1"><B>3(a)<BR> Title of the<BR>Class of<BR>Securities to<BR>be Sold</B></FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD align="center"><FONT size="1"><B>(b)<BR> Name and Address<BR>of Each Broker<BR>Through Whom the<BR>Securities Are to be<BR> Offered or Each<BR>Market Maker Who<BR>is Acquiring the Securities</B></FONT></TD> <TD align="center" nowrap><FONT size="1"><B>SEC USE<BR>ONLY</B><BR><BR><HR size="1" noshade><BR>
  <B>Broker-Dealer<BR>File Number</B></FONT></TD>
  <TD align="center" colspan="3" nowrap><FONT size="1"><B>(c)<BR> Number of<BR>Shares or Other<BR>Units to be Sold</B><BR><I>(See Instr. 3(c))</I></FONT></TD> <TD align="center" colspan="3" nowrap><FONT size="1"><B>(d)<BR> Aggregate<BR>Market Value</B><BR> <I>(See Instr. 3(d))</I></FONT></TD> <TD align="center" colspan="3" nowrap><FONT size="1"><B>(e)<BR>
  Number of<BR>Shares or Other<BR>Units Outstanding</B><BR><I>(See Instr. 3(e))</I></FONT></TD> <TD align="center" nowrap><FONT size="1"><B>(f)<BR> Approximate<BR>Date of Sale<BR>(Mo/Day/Yr)</B><BR><I>(See Instr. 3(f))</I></FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD align="center" nowrap><FONT size="1"><B>(g)<BR>Name of Each<BR>Securities<BR>Exchange</B><BR> <I>(See Instr. 3(g))</I></FONT></TD> </TR>
  <TR valign="bottom">  <TD colspan="16"><HR size="2" noshade></TD> </TR>
  <TR valign="bottom" bgcolor="#eeeeee">  <TD><FONT size="1">
  COMMON STOCK
  </FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD><FONT size="1">
  E*TRADE FINANCIAL<BR>1095 WHITE ROCK ROAD<BR>RANCHO CORDOVA, CA 95670
  </FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD align="right"><FONT size="1">&nbsp;</FONT></TD> <TD align="right" nowrap><FONT size="1">
  2,268(2)
  </FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD align="right"><FONT size="1">&nbsp;</FONT></TD> <TD align="right" nowrap><FONT size="1">
  $75,864.60
  </FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD align="right"><FONT size="1">
  34,008,554
  </FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD align="center"><FONT size="1">
  01/19/2007
  </FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD align="center"><FONT size="1">
  NASDAQ
  </FONT></TD> </TR>
  <TR valign="bottom">  <TD colspan="16"><HR size="2" noshade></TD> </TR>
  <TR valign="bottom">  <TD><FONT size="1">
  
  </FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD><FONT size="1">
  
  </FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD align="right"><FONT size="1">&nbsp;</FONT></TD> <TD align="right" nowrap><FONT size="1">
  
  </FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD align="right"><FONT size="1">&nbsp;</FONT></TD> <TD align="right" nowrap><FONT size="1">
  
  </FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD align="right"><FONT size="1">
  
  </FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD align="center"><FONT size="1">
  
  </FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD align="center"><FONT size="1">
  
  </FONT></TD> </TR>
  <TR valign="bottom">  <TD colspan="16"><HR size="2" noshade></TD> </TR>
  <TR valign="bottom" bgcolor="#eeeeee">  <TD><FONT size="1">
  
  </FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD><FONT size="1">
  
  </FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD align="right"><FONT size="1">&nbsp;</FONT></TD> <TD align="right" nowrap><FONT size="1">
  
  </FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD align="right"><FONT size="1">&nbsp;</FONT></TD> <TD align="right" nowrap><FONT size="1">
  
  </FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD align="right"><FONT size="1">
  
  </FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD align="center"><FONT size="1">
  
  </FONT></TD> <TD><FONT size="1">&nbsp;</FONT></TD> <TD align="center"><FONT size="1">
  
  </FONT></TD> </TR>
  </TABLE><P><FONT size="2"><b>INSTRUCTIONS:</b></FONT><TABLE cellspacing="0" cellpadding="0" width="100%" border="0"><TR valign="bottom"><TD width="3%">&nbsp;</TD><TD width="1%">&nbsp;</TD> <TD width="3%">&nbsp;</TD><TD width="1%">&nbsp;</TD><TD width="85%">&nbsp;</TD></TR><TR valign="bottom"> <TD valign="top">
  <FONT size="2">1.</FONT></TD> <TD></TD> <TD align="left" valign="top"><FONT size="2">(a)</FONT></TD> <TD></TD><TD align="left" valign="top"><FONT size="2">Name of issuer</FONT></TD> </TR><TR valign="bottom"><TD valign="top"></TD> <TD></TD><TD align="left" valign="top"><FONT size="2">(b)</FONT></TD><TD></TD><TD align="left" valign="top"><FONT size="2">Issuer&#146;s I.R.S. Identification Number</FONT></TD> </TR><TR valign="bottom"><TD valign="top"></TD><TD></TD><TD align="left" valign="top"><FONT size="2">(c)
  </FONT></TD><TD></TD><TD align="left" valign="top"><FONT size="2">Issuer&#146;s S.E.C. file number, if any</FONT></TD> </TR><TR valign="bottom"><TD valign="top"></TD><TD></TD><TD align="left" valign="top"><FONT size="2">(d)</FONT></TD><TD></TD><TD align="left" valign="top"><FONT size="2">Issuer&#146;s address, including zip code</FONT></TD></TR>
  <TR valign="bottom"><TD valign="top"></TD><TD></TD><TD align="left" valign="top"><FONT size="2">(e)</FONT></TD><TD></TD><TD align="left" valign="top"><FONT size="2">Issuer&#146;s telephone number, including area code</FONT></TD></TR> <TR><TD colspan="5"><FONT size="2">&nbsp;</FONT></TD></TR><TR valign="bottom"> <TD valign="top"><FONT size="2">2.</FONT></TD><TD></TD><TD align="left" valign="top"><FONT size="2">(a)</FONT></TD><TD></TD><TD align="left" valign="top">
  <FONT size="2">Name of person for whose account the securities are to be sold</FONT></TD></TR><TR valign="bottom"><TD valign="top"></TD><TD></TD><TD align="left" valign="top"><FONT size="2">(b)</FONT></TD><TD></TD><TD align="left" valign="top"><FONT size="2">Such person&#146;s I.R.S. Identification number, if such person is an entity</FONT></TD></TR>
  <TR valign="bottom"><TD valign="top"></TD><TD></TD><TD align="left" valign="top"><FONT size="2">(c)</FONT></TD><TD></TD> <TD align="left" valign="top"><FONT size="2">Such person&#146;s relationship to the issuer (e.g., officer, director, 10% stockholder, or member of immediate family of any of the foregoing)</FONT></TD></TR><TR valign="bottom"><TD valign="top"></TD><TD></TD><TD align="left" valign="top"><FONT size="2">(d)</FONT></TD><TD></TD><TD align="left" valign="top">
  <FONT size="2">Such person&#146;s address, including zip code</FONT></TD></TR><TR><TD colspan="5"><FONT size="2">&nbsp;</FONT></TD></TR><TR valign="bottom"><TD valign="top"><FONT size="2">3.</FONT></TD><TD></TD> <TD align="left" valign="top"><FONT size="2">(a)</FONT></TD><TD></TD><TD align="left" valign="top"><FONT size="2">Title of the class of securities to be sold</FONT></TD></TR><TR valign="bottom"><TD valign="top"></TD> <TD></TD><TD align="left" valign="top"><FONT size="2">(b)</FONT></TD>
  <TD></TD><TD align="left" valign="top"><FONT size="2">Name and Address of each broker through whom the securities are intended to be sold</FONT></TD></TR><TR valign="bottom"><TD valign="top"></TD><TD></TD><TD align="left" valign="top"><FONT size="2">(c)</FONT></TD> <TD></TD><TD align="left" valign="top"><FONT size="2">Number of shares or other units to be sold (if debt securities, give the aggregate face amount)</FONT></TD></TR><TR valign="bottom"><TD valign="top"></TD> <TD></TD>
  <TD align="left" valign="top"><FONT size="2">(d)</FONT></TD><TD></TD><TD align="left" valign="top"><FONT size="2">Aggregate market value of the securities to be sold as of a specified date within 10&nbsp;days prior to the filing of this notice</FONT></TD></TR><TR valign="bottom"><TD valign="top"></TD> <TD></TD><TD align="left" valign="top"><FONT size="2">(e)</FONT></TD>
  <TD></TD><TD align="left" valign="top"><FONT size="2">Number of shares or other units of the class outstanding, or if debt securities the face amount thereof outstanding, as shown by the most recent report or statement published by the issuer</FONT></TD></TR><TR valign="bottom"><TD valign="top"></TD><TD></TD><TD align="left" valign="top"><FONT size="2">(f)</FONT></TD><TD></TD><TD align="left" valign="top"><FONT size="2">Approximate date on which the securities are to be sold</FONT></TD></TR>
  <TR valign="bottom"><TD valign="top"></TD><TD></TD><TD align="left" valign="top"><FONT size="2">(g)</FONT></TD> <TD></TD><TD align="left" valign="top"><FONT size="2">Name of each securities exchange, if any, on which the securities are intended to be sold</FONT></TD></TR></TABLE>
  <P align="center"><FONT size="2">Page 2</FONT>
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metadata_documents: [{"type": "144", "sequence": "1", "filename": "f26670hse144.htm", "description": "FORM 144", "secsgml_size_bytes": 17401}]
text: e144
  OMB APPROVAL
  OMB Number: 3235-0101
  Expires: December 31, 2006
  Estimated average burden
  hours per response...4.47
  SEC USE ONLY
  DOCUMENT SEQUENCE NO.
  CUSIP NUMBER
  WORK LOCATION
  UNITED STATES
  SECURITIES AND EXCHANGE COMMISSION
  Washington, DC 20549
  FORM 144
  NOTICE OF PROPOSED SALE OF SECURITIES
  PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
  ATTENTION:
  Transmit for filing 3 copies of  this form concurrently with either placing an order with a broker to  execute sale or executing a sale directly with a market maker.
  1(a)
  Name of Issuer
  (b)
  IRS Ident. No.
  (c)
  S.E.C. File No.
  INTERMUNE, INC.
  94-3296648
  0-29801
  (d)
  Address of Issuer
  (e)
  Telephone
  3280 Bayshore Boulevard
  Brisbane
  , 
  CA
    
  94005
  415
   
  466-2200
  (Street)
  (City)      (State)       (Zip Code)
  (Area Code)   (Number)
  2(a)
  Name of Person For Whose Account the
  Securities are to be Sold
  (b)
  IRS Ident. No.
  (c)
  Relationship to Issuer
  Howard Allan Simon
  Officer
  (d)
  Address
  3280 Bayshore Boulevard
  Brisbane
  , 
  CA
    
  94005
  (Street)
  (City)      (State)        (Zip Code)
  INSTRUCTION:
  The person filing this notice should contact  the issuer to obtain the I.R.S. Identification Number and the S.E.C. File Number
  3(a)
  Title of the
  Class of
  Securities to
  be Sold
  (b)
  Name and Address
  of Each Broker
  Through Whom the
  Securities Are to be
  Offered or Each
  Market Maker Who
  is Acquiring the Securities
  SEC USE
  ONLY
  Broker-Dealer
  File Number
  (c)
  Number of
  Shares or Other
  Units to be Sold
  (See Instr. 3(c))
  (d)
  Aggregate
  Market Value
  (See Instr. 3(d))
  (e)
  Number of
  Shares or Other
  Units Outstanding
  (See Instr. 3(e))
  (f)
  Approximate
  Date of Sale
  (Mo/Day/Yr)
  (See Instr. 3(f))
  (g)
  Name of Each
  Securities
  Exchange
  (See Instr. 3(g))
  COMMON STOCK
  E*TRADE FINANCIAL
  1095 WHITE ROCK ROAD
  RANCHO CORDOVA, CA 95670
  2,268(2)
  $75,864.60
  34,008,554
  01/19/2007
  NASDAQ
  INSTRUCTIONS:
  1.
  (a)
  Name of issuer
  (b)
  Issuer's I.R.S. Identification Number
  (c)
  Issuer's S.E.C. file number, if any
  (d)
  Issuer's address, including zip code
  (e)
  Issuer's telephone number, including area code
  2.
  (a)
  Name of person for whose account the securities are to be sold
  (b)
  Such person's I.R.S. Identification number, if such person is an entity
  (c)
  Such person's relationship to the issuer (e.g., officer, director, 10% stockholder, or member of immediate family of any of the foregoing)
  (d)
  Such person's address, including zip code
  3.
  (a)
  Title of the class of securities to be sold
  (b)
  Name and Address of each broker through whom the securities are intended to be sold
  (c)
  Number of shares or other units to be sold (if debt securities, give the aggregate face amount)
  (d)
  Aggregate market value of the securities to be sold as of a specified date within 10 days prior to the filing of this notice
  (e)
  Number of shares or other units of the class outstanding, or if debt securities the face amount thereof outstanding, as shown by the most recent report or statement published by the issuer
  (f)
  Approximate date on which the securities are to be sold
  (g)
  Name of each securities exchange, if any, on which the securities are intended to be sold
  Page 2