content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <!-- Generated by Workiva -->
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001202432</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0000740260</issuerCik>
        <issuerName>Ventas, Inc.</issuerName>
        <secFileNumber>001-10989</secFileNumber>
        <issuerAddress>
          <com:street1>353 N. Clark Street, Suite 3300</com:street1>
          <com:city>Chicago</com:city>
          <com:stateOrCountry>IL</com:stateOrCountry>
          <com:zipCode>60654</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>877-483-6827</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Walter C. Rakowich</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Director</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>JP Morgan Securities LLC</name>
          <address>
            <com:street1>390 Madison Avenue</com:street1>
            <com:street2>6th Floor</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10017</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>1459</noOfUnitsSold>
        <aggregateMarketValue>93638.62</aggregateMarketValue>
        <noOfUnitsOutstanding>451298340</noOfUnitsOutstanding>
        <approxSaleDate>05/14/2025</approxSaleDate>
        <securitiesExchangeName>NYSE</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>05/13/2025</acquiredDate>
        <natureOfAcquisitionTransaction>RSU grant</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>1459</amountOfSecuritiesAcquired>
        <paymentDate>05/13/2025</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <remarks>RSUs were granted on May 14, 2024.</remarks>
      <noticeSignature>
        <noticeDate>05/14/2025</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>09/15/2024</planAdoptionDate>
        </planAdoptionDates>
        <signature>/s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Walter C. Rakowich</signature>
      </noticeSignature>
    </formData>
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text: 144
  0001202432
  XXXXXXXX
  LIVE
  0000740260
  Ventas, Inc.
  001-10989
  353 N. Clark Street, Suite 3300
  Chicago
  IL
  60654
  877-483-6827
  Walter C. Rakowich
  Director
  Common
  JP Morgan Securities LLC
  390 Madison Avenue
  6th Floor
  New York
  NY
  10017
  1459
  93638.62
  451298340
  05/14/2025
  NYSE
  Common
  05/13/2025
  RSU grant
  Issuer
  N
  1459
  05/13/2025
  Compensation
  Y
  RSUs were granted on May 14, 2024.
  05/14/2025
  09/15/2024
  /s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Walter C. Rakowich