content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
  <submissionType>144</submissionType>
  <filerInfo>
  <filer>
  <filerCredentials>
  <cik>0001983495</cik>
  <ccc>XXXXXXXX</ccc>
  </filerCredentials>
  </filer>
  <liveTestFlag>LIVE</liveTestFlag>
  
  
  
  </filerInfo>
  </headerData>
  <formData>
  <issuerInfo>
  <issuerCik>0001503584</issuerCik>
  <issuerName>Costamare Inc.</issuerName>
  <secFileNumber>001-34934</secFileNumber>
  <issuerAddress>
  <com:street1>7 rue du Gabian</com:street1>
  <com:city>Monaco</com:city>
  <com:stateOrCountry>O9</com:stateOrCountry>
  <com:zipCode>98000</com:zipCode>
  </issuerAddress>
  <issuerContactPhone>377-93 25 09 40</issuerContactPhone>
  <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Eirini Gkouma</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
  <relationshipsToIssuer>
  <relationshipToIssuer>SPOUSE OF CHAIRMAN AND CEO K. KONSTANTAKOPOULOS</relationshipToIssuer>
  </relationshipsToIssuer>
  </issuerInfo>
  <securitiesInformation>
  <securitiesClassTitle>COMMON SHARES</securitiesClassTitle>
  <brokerOrMarketmakerDetails>
  <name>HSBC BANK USA</name>
  <address>
  <com:street1>66 Hudson Boulevard E</com:street1>
  <com:city>New York</com:city>
  <com:stateOrCountry>NY</com:stateOrCountry>
  <com:zipCode>10001</com:zipCode>
  </address>
  </brokerOrMarketmakerDetails>
  <noOfUnitsSold>50000</noOfUnitsSold>
  <aggregateMarketValue>740000</aggregateMarketValue>
  <noOfUnitsOutstanding>118944401</noOfUnitsOutstanding>
  <approxSaleDate>05/28/2024</approxSaleDate>
  <securitiesExchangeName>NYSE</securitiesExchangeName>
  </securitiesInformation>
  <securitiesToBeSold>
  <securitiesClassTitle>COMMON</securitiesClassTitle>
  <acquiredDate>09/30/2021</acquiredDate>
  <natureOfAcquisitionTransaction>DONATION BY SPOUSE</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>KONSTANTINOS KONSTANTAKOPOULOS</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>Y</isGiftTransaction>
  <donarAcquiredDate>05/08/2017</donarAcquiredDate>
  <amountOfSecuritiesAcquired>300000</amountOfSecuritiesAcquired>
  <paymentDate>09/30/2021</paymentDate>
  <natureOfPayment>cashless</natureOfPayment>
  </securitiesToBeSold>
  <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
  <noticeSignature>
  <noticeDate>05/29/2024</noticeDate>
  <signature>/s/ Eirini Gkouma</signature>
  </noticeSignature>
  </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 2429}]
text: 144
  0001983495
  XXXXXXXX
  LIVE
  0001503584
  Costamare Inc.
  001-34934
  7 rue du Gabian
  Monaco
  O9
  98000
  377-93 25 09 40
  Eirini Gkouma
  SPOUSE OF CHAIRMAN AND CEO K. KONSTANTAKOPOULOS
  COMMON SHARES
  HSBC BANK USA
  66 Hudson Boulevard E
  New York
  NY
  10001
  50000
  740000
  118944401
  05/28/2024
  NYSE
  COMMON
  09/30/2021
  DONATION BY SPOUSE
  KONSTANTINOS KONSTANTAKOPOULOS
  Y
  05/08/2017
  300000
  09/30/2021
  cashless
  Y
  05/29/2024
  /s/ Eirini Gkouma