content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <!-- Field: Pseudo-Tag; ID: Name; Data: ORBIMED CAPITAL LLC -->
            <cik>0001157524</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001800315</issuerCik>
        <issuerName>Galecto</issuerName>
        <secFileNumber>001-39655</secFileNumber>
        <issuerAddress>
          <com:street1>75 State Street</com:street1>
          <com:street2>Suite 100</com:street2>
          <com:city>Boston</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>02109</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>45-70-70-52-10</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>The Biotech Growth Trust PLC</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Shareholder</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Themis Trading LLC</name>
          <address>
            <com:street1>10 Town Square</com:street1>
            <com:street2>Suite 100</com:street2>
            <com:city>Chatham</com:city>
            <com:stateOrCountry>NJ</com:stateOrCountry>
            <com:zipCode>07928</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>2512</noOfUnitsSold>
        <aggregateMarketValue>4772.80</aggregateMarketValue>
        <noOfUnitsOutstanding>25673474</noOfUnitsOutstanding>
        <approxSaleDate>04/10/2023</approxSaleDate>
        <securitiesExchangeName>Nasdaq Stock Market</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <acquiredDate>09/25/2020</acquiredDate>
        <natureOfAcquisitionTransaction>Private placement</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>2512</amountOfSecuritiesAcquired>
        <paymentDate>09/25/2020</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>The Biotech Growth Trust PLC</name>
          <address>
            <com:street1>601 Lexington Ave.</com:street1>
            <com:street2>54th Floor</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10022</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <saleDate>04/05/2023</saleDate>
        <amountOfSecuritiesSold>7035</amountOfSecuritiesSold>
        <grossProceeds>15336.30</grossProceeds>
      </securitiesSoldInPast3Months>
      <remarks>OrbiMed Capital LLC is the portfolio manager of The Biotech Growth Trust PLC. Additional sales made on April 6, 2023. The Biotech Growth Trust PLC sold 735 shares of Common Stock for gross proceeds of $1,470.</remarks>
      <noticeSignature>
        <noticeDate>04/10/2023</noticeDate>
        <signature>/s/ Douglas Coon, Chief Compliance Officer, OrbiMed Capital LLC, portfolio manager for The Biotech Growth Trust PLC</signature>
      </noticeSignature>
    </formData>
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text: 144
  0001157524
  XXXXXXXX
  LIVE
  0001800315
  Galecto
  001-39655
  75 State Street
  Suite 100
  Boston
  MA
  02109
  45-70-70-52-10
  The Biotech Growth Trust PLC
  Shareholder
  Common Stock
  Themis Trading LLC
  10 Town Square
  Suite 100
  Chatham
  NJ
  07928
  2512
  4772.80
  25673474
  04/10/2023
  Nasdaq Stock Market
  Common Stock
  09/25/2020
  Private placement
  Issuer
  N
  2512
  09/25/2020
  Cash
  N
  The Biotech Growth Trust PLC
  601 Lexington Ave.
  54th Floor
  New York
  NY
  10022
  Common Stock
  04/05/2023
  7035
  15336.30
  OrbiMed Capital LLC is the portfolio manager of The Biotech Growth Trust PLC. Additional sales made on April 6, 2023. The Biotech Growth Trust PLC sold 735 shares of Common Stock for gross proceeds of $1,470.
  04/10/2023
  /s/ Douglas Coon, Chief Compliance Officer, OrbiMed Capital LLC, portfolio manager for The Biotech Growth Trust PLC