content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <!-- Generated by Workiva -->
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001834171</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001559720</issuerCik>
        <issuerName>Airbnb, Inc.</issuerName>
        <secFileNumber>001-39778</secFileNumber>
        <issuerAddress>
          <com:street1>888 Brannan Street</com:street1>
          <com:city>San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94103</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>415-728-0108</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Joseph Gebbia</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Director</relationshipToIssuer>
          <relationshipToIssuer>10% Shareholder</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>J.P. Morgan Securities LLC</name>
          <address>
            <com:street1>390 Madison Avenue, 6th Floor</com:street1>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10017</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>1500005</noOfUnitsSold>
        <aggregateMarketValue>217170723</aggregateMarketValue>
        <noOfUnitsOutstanding>432876657</noOfUnitsOutstanding>
        <approxSaleDate>02/25/2025</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <acquiredDate>10/27/2020</acquiredDate>
        <natureOfAcquisitionTransaction>Transfer</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Joseph Gebbia, who acquired Founder shares on 07/15/09</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>1500005</amountOfSecuritiesAcquired>
        <paymentDate>10/27/2020</paymentDate>
        <natureOfPayment>N/A</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>Joseph Gebbia</name>
          <address>
            <com:street1>C/o AirBNB, Inc.</com:street1>
            <com:street2>888 Brannan Street</com:street2>
            <com:city>San Francisco</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>94103</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <saleDate>12/03/2024</saleDate>
        <amountOfSecuritiesSold>19448</amountOfSecuritiesSold>
        <grossProceeds>2667195</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>The Sycamore Trust</name>
          <address>
            <com:street1>C/o AirBNB, Inc.</com:street1>
            <com:street2>888 Brannan Street</com:street2>
            <com:city>San Francisco</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>94103</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <saleDate>12/03/2024</saleDate>
        <amountOfSecuritiesSold>214285</amountOfSecuritiesSold>
        <grossProceeds>29383628</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>The Sycamore Trust</name>
          <address>
            <com:street1>C/o AirBNB, Inc.</com:street1>
            <com:street2>888 Brannan Street</com:street2>
            <com:city>San Francisco</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>94103</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <saleDate>12/17/2024</saleDate>
        <amountOfSecuritiesSold>214285</amountOfSecuritiesSold>
        <grossProceeds>28260150</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>The Sycamore Trust</name>
          <address>
            <com:street1>C/o AirBNB, Inc.</com:street1>
            <com:street2>888 Brannan Street</com:street2>
            <com:city>San Francisco</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>94103</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <saleDate>01/06/2025</saleDate>
        <amountOfSecuritiesSold>214285</amountOfSecuritiesSold>
        <grossProceeds>29130777</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>The Sycamore Trust</name>
          <address>
            <com:street1>C/o AirBNB, Inc.</com:street1>
            <com:street2>888 Brannan Street</com:street2>
            <com:city>San Francisco</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>94103</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <saleDate>01/14/2025</saleDate>
        <amountOfSecuritiesSold>214285</amountOfSecuritiesSold>
        <grossProceeds>27631674</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>The Sycamore Trust</name>
          <address>
            <com:street1>C/o AirBNB, Inc.</com:street1>
            <com:street2>888 Brannan Street</com:street2>
            <com:city>San Francisco</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>94103</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <saleDate>01/28/2025</saleDate>
        <amountOfSecuritiesSold>214285</amountOfSecuritiesSold>
        <grossProceeds>27687055</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>The Sycamore Trust</name>
          <address>
            <com:street1>C/o AirBNB, Inc.</com:street1>
            <com:street2>888 Brannan Street</com:street2>
            <com:city>San Francisco</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>94103</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <saleDate>02/11/2025</saleDate>
        <amountOfSecuritiesSold>214285</amountOfSecuritiesSold>
        <grossProceeds>28936167</grossProceeds>
      </securitiesSoldInPast3Months>
      <remarks>The shares filed today will be sold by The Sycamore Trust, Joseph Gebbia as Trustee.</remarks>
      <noticeSignature>
        <noticeDate>02/25/2025</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>08/20/2024</planAdoptionDate>
        </planAdoptionDates>
        <signature>/s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Joseph Gebbia</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 7779}]
text: 144
  0001834171
  XXXXXXXX
  LIVE
  0001559720
  Airbnb, Inc.
  001-39778
  888 Brannan Street
  San Francisco
  CA
  94103
  415-728-0108
  Joseph Gebbia
  Director
  10% Shareholder
  Class A Common Stock
  J.P. Morgan Securities LLC
  390 Madison Avenue, 6th Floor
  New York
  NY
  10017
  1500005
  217170723
  432876657
  02/25/2025
  NASDAQ
  Class A Common Stock
  10/27/2020
  Transfer
  Joseph Gebbia, who acquired Founder shares on 07/15/09
  N
  1500005
  10/27/2020
  N/A
  N
  Joseph Gebbia
  C/o AirBNB, Inc.
  888 Brannan Street
  San Francisco
  CA
  94103
  Class A Common Stock
  12/03/2024
  19448
  2667195
  The Sycamore Trust
  C/o AirBNB, Inc.
  888 Brannan Street
  San Francisco
  CA
  94103
  Class A Common Stock
  12/03/2024
  214285
  29383628
  The Sycamore Trust
  C/o AirBNB, Inc.
  888 Brannan Street
  San Francisco
  CA
  94103
  Class A Common Stock
  12/17/2024
  214285
  28260150
  The Sycamore Trust
  C/o AirBNB, Inc.
  888 Brannan Street
  San Francisco
  CA
  94103
  Class A Common Stock
  01/06/2025
  214285
  29130777
  The Sycamore Trust
  C/o AirBNB, Inc.
  888 Brannan Street
  San Francisco
  CA
  94103
  Class A Common Stock
  01/14/2025
  214285
  27631674
  The Sycamore Trust
  C/o AirBNB, Inc.
  888 Brannan Street
  San Francisco
  CA
  94103
  Class A Common Stock
  01/28/2025
  214285
  27687055
  The Sycamore Trust
  C/o AirBNB, Inc.
  888 Brannan Street
  San Francisco
  CA
  94103
  Class A Common Stock
  02/11/2025
  214285
  28936167
  The shares filed today will be sold by The Sycamore Trust, Joseph Gebbia as Trustee.
  02/25/2025
  08/20/2024
  /s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Joseph Gebbia