content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001015013</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0000313616</issuerCik>
        <issuerName>DANAHER CORP /DE/</issuerName>
        <secFileNumber>001-08089</secFileNumber>
        <issuerAddress>
          <com:street1>2200 PENNSYLVANIA AVE. N.W.</com:street1>
          <com:street2>SUITE 800W</com:street2>
          <com:city>WASHINGTON</com:city>
          <com:stateOrCountry>DC</com:stateOrCountry>
          <com:zipCode>20037-1701</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>2028280850</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>RALES STEVEN M</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
          <relationshipToIssuer>Director</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Monness, Crespi, Hardt &amp; Co., Inc.</name>
          <address>
            <com:street1>767 Third Avenue, 16th Floor</com:street1>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10017</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>1250000</noOfUnitsSold>
        <aggregateMarketValue>243525000.00</aggregateMarketValue>
        <noOfUnitsOutstanding>715669594</noOfUnitsOutstanding>
        <approxSaleDate>05/12/2025</approxSaleDate>
        <securitiesExchangeName>NYSE</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <acquiredDate>06/11/2021</acquiredDate>
        <natureOfAcquisitionTransaction>Pro rata distribution from co-owned entity</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Co-owned entity</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>1250000</amountOfSecuritiesAcquired>
        <paymentDate>06/11/2021</paymentDate>
        <natureOfPayment>Not Applicable</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>05/12/2025</noticeDate>
        <signature>Steven M. Rales</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 2902}]
text: 144
  0001015013
  XXXXXXXX
  LIVE
  0000313616
  DANAHER CORP /DE/
  001-08089
  2200 PENNSYLVANIA AVE. N.W.
  SUITE 800W
  WASHINGTON
  DC
  20037-1701
  2028280850
  RALES STEVEN M
  Officer
  Director
  Common Stock
  Monness, Crespi, Hardt & Co., Inc.
  767 Third Avenue, 16th Floor
  New York
  NY
  10017
  1250000
  243525000.00
  715669594
  05/12/2025
  NYSE
  Common Stock
  06/11/2021
  Pro rata distribution from co-owned entity
  Co-owned entity
  N
  1250000
  06/11/2021
  Not Applicable
  Y
  05/12/2025
  Steven M. Rales