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  <street2 xmlns="http://www.sec.gov/edgar/common">Suite 201</street2>
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  <issuerContactPhone>978-645-5500</issuerContactPhone>
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  <securitiesClassTitle>Common Stock</securitiesClassTitle>
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  <city xmlns="http://www.sec.gov/edgar/common">New York</city>
  <stateOrCountry xmlns="http://www.sec.gov/edgar/common">NY</stateOrCountry>
  <zipCode xmlns="http://www.sec.gov/edgar/common">10179</zipCode>
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  <noOfUnitsOutstanding>66767385</noOfUnitsOutstanding>
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  <securitiesExchangeName>NASDAQ</securitiesExchangeName>
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  <acquiredDate>08/17/2022</acquiredDate>
  <natureOfAcquisitionTransaction>Acquired upon exchange of common shares of Atotech Limited for per share consideration of cash and shares of Common Stock of the Issuer.</natureOfAcquisitionTransaction>
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  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>5180030</amountOfSecuritiesAcquired>
  <paymentDate>08/17/2022</paymentDate>
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  <name>Carlyle Partners VI Cayman Holdings, L.P.</name>
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  <street1 xmlns="http://www.sec.gov/edgar/common">c/o Walkers Corporate Services Limited</street1>
  <street2 xmlns="http://www.sec.gov/edgar/common">190 Elgin Avenue</street2>
  <city xmlns="http://www.sec.gov/edgar/common">George Town, Grand Cayman</city>
  <stateOrCountry xmlns="http://www.sec.gov/edgar/common">E9</stateOrCountry>
  <zipCode xmlns="http://www.sec.gov/edgar/common">KY1-9001</zipCode>
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  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <saleDate>05/08/2023</saleDate>
  <amountOfSecuritiesSold>1221311</amountOfSecuritiesSold>
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  <saleDate>06/01/2023</saleDate>
  <amountOfSecuritiesSold>1221312</amountOfSecuritiesSold>
  <grossProceeds>118174149.12</grossProceeds>
  </securitiesSoldInPast3Months>
  <noticeSignature>
  <noticeDate>06/28/2023</noticeDate>
  <signature>Carlyle Partners VI Cayman Holdings, L.P., By: TC Group VI Cayman, L.P., By: TC Group VI Cayman, L.L.C., By: /s/ Jeremy W. Anderson, Authorized Person</signature>
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text: 144
  0001838776
  XXXXXXXX
  LIVE
  0001049502
  MKS Instruments, Inc.
  000-23621
  2 Tech Drive
  Suite 201
  Andover
  MA
  01810
  978-645-5500
  Carlyle Partners VI Cayman Holdings, L.P.
  Former 10% stockholder
  Common Stock
  J.P. Morgan Securities LLC
  383 Madison Avenue
  New York
  NY
  10179
  610656
  65492856.00
  66767385
  06/28/2023
  NASDAQ
  Common Stock
  08/17/2022
  Acquired upon exchange of common shares of Atotech Limited for per share consideration of cash and shares of Common Stock of the Issuer.
  Issuer
  N
  5180030
  08/17/2022
  Share exchange
  N
  Carlyle Partners VI Cayman Holdings, L.P.
  c/o Walkers Corporate Services Limited
  190 Elgin Avenue
  George Town, Grand Cayman
  E9
  KY1-9001
  Common Stock
  05/08/2023
  1221311
  105185409.88
  Carlyle Partners VI Cayman Holdings, L.P.
  c/o Walkers Corporate Services Limited
  190 Elgin Avenue
  George Town, Grand Cayman
  E9
  KY1-9001
  Common Stock
  06/01/2023
  1221312
  118174149.12
  06/28/2023
  Carlyle Partners VI Cayman Holdings, L.P., By: TC Group VI Cayman, L.P., By: TC Group VI Cayman, L.L.C., By: /s/ Jeremy W. Anderson, Authorized Person