content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <!-- Generated by Workiva -->
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001834171</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001559720</issuerCik>
        <issuerName>Airbnb, Inc.</issuerName>
        <secFileNumber>001-39778</secFileNumber>
        <issuerAddress>
          <com:street1>888 Brannan Street</com:street1>
          <com:city>San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94103</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>415-728-0108</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Joseph Gebbia</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Director</relationshipToIssuer>
          <relationshipToIssuer>10% Shareholder</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>J.P. Morgan Securities LLC</name>
          <address>
            <com:street1>390 Madison Avenue, 6th Floor</com:street1>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10017</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>1654509</noOfUnitsSold>
        <aggregateMarketValue>214093465</aggregateMarketValue>
        <noOfUnitsOutstanding>431602213</noOfUnitsOutstanding>
        <approxSaleDate>05/28/2025</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <acquiredDate>05/25/2025</acquiredDate>
        <natureOfAcquisitionTransaction>Compensation</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>2509</amountOfSecuritiesAcquired>
        <paymentDate>05/25/2025</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <acquiredDate>10/27/2020</acquiredDate>
        <natureOfAcquisitionTransaction>Transfer</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Joseph Gebbia, who acquired Founder shares on 07/15/09</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>1652000</amountOfSecuritiesAcquired>
        <paymentDate>10/27/2020</paymentDate>
        <natureOfPayment>N/A</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>The Sycamore Trust</name>
          <address>
            <com:street1>C/o AirBNB, Inc.</com:street1>
            <com:street2>888 Brannan Street</com:street2>
            <com:city>San Francisco</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>94103</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <saleDate>03/11/2025</saleDate>
        <amountOfSecuritiesSold>214285</amountOfSecuritiesSold>
        <grossProceeds>27170765</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>The Sycamore Trust</name>
          <address>
            <com:street1>C/o AirBNB, Inc.</com:street1>
            <com:street2>888 Brannan Street</com:street2>
            <com:city>San Francisco</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>94103</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <saleDate>03/25/2025</saleDate>
        <amountOfSecuritiesSold>214285</amountOfSecuritiesSold>
        <grossProceeds>27724153</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>The Sycamore Trust</name>
          <address>
            <com:street1>C/o AirBNB, Inc.</com:street1>
            <com:street2>888 Brannan Street</com:street2>
            <com:city>San Francisco</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>94103</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <saleDate>04/08/2025</saleDate>
        <amountOfSecuritiesSold>214285</amountOfSecuritiesSold>
        <grossProceeds>23304629</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>The Sycamore Trust</name>
          <address>
            <com:street1>C/o AirBNB, Inc.</com:street1>
            <com:street2>888 Brannan Street</com:street2>
            <com:city>San Francisco</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>94103</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <saleDate>04/22/2025</saleDate>
        <amountOfSecuritiesSold>214285</amountOfSecuritiesSold>
        <grossProceeds>24476148</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>The Sycamore Trust</name>
          <address>
            <com:street1>C/o AirBNB, Inc.</com:street1>
            <com:street2>888 Brannan Street</com:street2>
            <com:city>San Francisco</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>94103</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <saleDate>05/06/2025</saleDate>
        <amountOfSecuritiesSold>214285</amountOfSecuritiesSold>
        <grossProceeds>26322887</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>The Sycamore Trust</name>
          <address>
            <com:street1>C/o AirBNB, Inc.</com:street1>
            <com:street2>888 Brannan Street</com:street2>
            <com:city>San Francisco</com:city>
            <com:stateOrCountry>CA</com:stateOrCountry>
            <com:zipCode>94103</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
        <saleDate>05/20/2025</saleDate>
        <amountOfSecuritiesSold>214285</amountOfSecuritiesSold>
        <grossProceeds>28397324</grossProceeds>
      </securitiesSoldInPast3Months>
      <remarks>Of the shares filed today,  2,509 shares will be sold by Joseph Gebbia and 1,652,000 shares will be sold by The Sycamore Trust, Joseph Gebbia as Trustee.</remarks>
      <noticeSignature>
        <noticeDate>05/28/2025</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>02/26/2025</planAdoptionDate>
        </planAdoptionDates>
        <signature>/s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Joseph Gebbia</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 7734}]
text: 144
  0001834171
  XXXXXXXX
  LIVE
  0001559720
  Airbnb, Inc.
  001-39778
  888 Brannan Street
  San Francisco
  CA
  94103
  415-728-0108
  Joseph Gebbia
  Director
  10% Shareholder
  Class A Common Stock
  J.P. Morgan Securities LLC
  390 Madison Avenue, 6th Floor
  New York
  NY
  10017
  1654509
  214093465
  431602213
  05/28/2025
  NASDAQ
  Class A Common Stock
  05/25/2025
  Compensation
  Issuer
  N
  2509
  05/25/2025
  Compensation
  Class A Common Stock
  10/27/2020
  Transfer
  Joseph Gebbia, who acquired Founder shares on 07/15/09
  N
  1652000
  10/27/2020
  N/A
  N
  The Sycamore Trust
  C/o AirBNB, Inc.
  888 Brannan Street
  San Francisco
  CA
  94103
  Class A Common Stock
  03/11/2025
  214285
  27170765
  The Sycamore Trust
  C/o AirBNB, Inc.
  888 Brannan Street
  San Francisco
  CA
  94103
  Class A Common Stock
  03/25/2025
  214285
  27724153
  The Sycamore Trust
  C/o AirBNB, Inc.
  888 Brannan Street
  San Francisco
  CA
  94103
  Class A Common Stock
  04/08/2025
  214285
  23304629
  The Sycamore Trust
  C/o AirBNB, Inc.
  888 Brannan Street
  San Francisco
  CA
  94103
  Class A Common Stock
  04/22/2025
  214285
  24476148
  The Sycamore Trust
  C/o AirBNB, Inc.
  888 Brannan Street
  San Francisco
  CA
  94103
  Class A Common Stock
  05/06/2025
  214285
  26322887
  The Sycamore Trust
  C/o AirBNB, Inc.
  888 Brannan Street
  San Francisco
  CA
  94103
  Class A Common Stock
  05/20/2025
  214285
  28397324
  Of the shares filed today,  2,509 shares will be sold by Joseph Gebbia and 1,652,000 shares will be sold by The Sycamore Trust, Joseph Gebbia as Trustee.
  05/28/2025
  02/26/2025
  /s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Joseph Gebbia