content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:xsd="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
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  <filerCredentials>
  <cik>0001560959</cik>
  <ccc>XXXXXXXX</ccc>
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  <liveTestFlag>LIVE</liveTestFlag>
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  <issuerInfo>
  <issuerCik>0001815442</issuerCik>
  <issuerName>KYMERA THERAPEUTICS, INC.</issuerName>
  <secFileNumber>001-39460</secFileNumber>
  <issuerAddress>
  <street1 xmlns="http://www.sec.gov/edgar/common">500 NORTH BEACON STREET</street1>
  <street2 xmlns="http://www.sec.gov/edgar/common">4TH FLOOR</street2>
  <city xmlns="http://www.sec.gov/edgar/common">WATERTOWN</city>
  <stateOrCountry xmlns="http://www.sec.gov/edgar/common">MA</stateOrCountry>
  <zipCode xmlns="http://www.sec.gov/edgar/common">02472</zipCode>
  </issuerAddress>
  <issuerContactPhone>857-285-5300</issuerContactPhone>
  <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>JOANNA HOROBIN</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
  <relationshipsToIssuer>
  <relationshipToIssuer>FORMER DIRECTOR</relationshipToIssuer>
  </relationshipsToIssuer>
  </issuerInfo>
  <securitiesInformation>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <brokerOrMarketmakerDetails>
  <name>Morgan Stanley Smith Barney LLC</name>
  <address>
  <street1 xmlns="http://www.sec.gov/edgar/common">1 New York Plaza</street1>
  <street2 xmlns="http://www.sec.gov/edgar/common">38th Floor</street2>
  <city xmlns="http://www.sec.gov/edgar/common">New York</city>
  <stateOrCountry xmlns="http://www.sec.gov/edgar/common">NY</stateOrCountry>
  <zipCode xmlns="http://www.sec.gov/edgar/common">10004</zipCode>
  </address>
  </brokerOrMarketmakerDetails>
  <noOfUnitsSold>66958</noOfUnitsSold>
  <aggregateMarketValue>2948830.00</aggregateMarketValue>
  <noOfUnitsOutstanding>61358262</noOfUnitsOutstanding>
  <approxSaleDate>07/25/2024</approxSaleDate>
  <securitiesExchangeName>NASDAQ</securitiesExchangeName>
  </securitiesInformation>
  <securitiesToBeSold>
  <securitiesClassTitle>Common Stock</securitiesClassTitle>
  <acquiredDate>07/25/2024</acquiredDate>
  <natureOfAcquisitionTransaction>Exercise of Stock Options</natureOfAcquisitionTransaction>
  <nameOfPersonfromWhomAcquired>KYMERA THERAPEUTICS, INC.</nameOfPersonfromWhomAcquired>
  <isGiftTransaction>N</isGiftTransaction>
  <amountOfSecuritiesAcquired>66958</amountOfSecuritiesAcquired>
  <paymentDate>07/25/2024</paymentDate>
  <natureOfPayment>Cash</natureOfPayment>
  </securitiesToBeSold>
  <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
  <securitiesSoldInPast3Months>
  <sellerDetails>
  <name>Joanna Horobin</name>
  <address>
  <street1 xmlns="http://www.sec.gov/edgar/common">500 North Beacon Street</street1>
  <street2 xmlns="http://www.sec.gov/edgar/common">4th Floor</street2>
  <city xmlns="http://www.sec.gov/edgar/common">Watertown</city>
  <stateOrCountry xmlns="http://www.sec.gov/edgar/common">MA</stateOrCountry>
  <zipCode xmlns="http://www.sec.gov/edgar/common">02472</zipCode>
  </address>
  </sellerDetails>
  <securitiesClassTitle>Common</securitiesClassTitle>
  <saleDate>06/07/2024</saleDate>
  <amountOfSecuritiesSold>8500</amountOfSecuritiesSold>
  <grossProceeds>280400.00</grossProceeds>
  </securitiesSoldInPast3Months>
  <securitiesSoldInPast3Months>
  <sellerDetails>
  <name>Joanna Horobin</name>
  <address>
  <street1 xmlns="http://www.sec.gov/edgar/common">500 North Beacon Street</street1>
  <street2 xmlns="http://www.sec.gov/edgar/common">4th Floor</street2>
  <city xmlns="http://www.sec.gov/edgar/common">Watertown</city>
  <stateOrCountry xmlns="http://www.sec.gov/edgar/common">MA</stateOrCountry>
  <zipCode xmlns="http://www.sec.gov/edgar/common">02472</zipCode>
  </address>
  </sellerDetails>
  <securitiesClassTitle>Common</securitiesClassTitle>
  <saleDate>07/23/2024</saleDate>
  <amountOfSecuritiesSold>15000</amountOfSecuritiesSold>
  <grossProceeds>648842.00</grossProceeds>
  </securitiesSoldInPast3Months>
  <noticeSignature>
  <noticeDate>07/25/2024</noticeDate>
  <signature>/s/ Joanna Horobin</signature>
  </noticeSignature>
  </formData>
  </edgarSubmission>
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text: 144
  0001560959
  XXXXXXXX
  LIVE
  0001815442
  KYMERA THERAPEUTICS, INC.
  001-39460
  500 NORTH BEACON STREET
  4TH FLOOR
  WATERTOWN
  MA
  02472
  857-285-5300
  JOANNA HOROBIN
  FORMER DIRECTOR
  Common Stock
  Morgan Stanley Smith Barney LLC
  1 New York Plaza
  38th Floor
  New York
  NY
  10004
  66958
  2948830.00
  61358262
  07/25/2024
  NASDAQ
  Common Stock
  07/25/2024
  Exercise of Stock Options
  KYMERA THERAPEUTICS, INC.
  N
  66958
  07/25/2024
  Cash
  N
  Joanna Horobin
  500 North Beacon Street
  4th Floor
  Watertown
  MA
  02472
  Common
  06/07/2024
  8500
  280400.00
  Joanna Horobin
  500 North Beacon Street
  4th Floor
  Watertown
  MA
  02472
  Common
  07/23/2024
  15000
  648842.00
  07/25/2024
  /s/ Joanna Horobin