content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <!-- Generated by Workiva -->
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001311548</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0000318300</issuerCik>
        <issuerName>Peoples Bancorp Inc.</issuerName>
        <secFileNumber>000-16772</secFileNumber>
        <issuerAddress>
          <com:street1>138 Putnam Street</com:street1>
          <com:city>Marietta</com:city>
          <com:stateOrCountry>OH</com:stateOrCountry>
          <com:zipCode>45750</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>740-373-3155</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>David F. Dierker</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Affiliate</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>J.P. Morgan Securities LLC</name>
          <address>
            <com:street1>390 Madison Avenue - 6th Floor</com:street1>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10017</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>7500</noOfUnitsSold>
        <aggregateMarketValue>270150</aggregateMarketValue>
        <noOfUnitsOutstanding>35508377</noOfUnitsOutstanding>
        <approxSaleDate>11/26/2024</approxSaleDate>
        <securitiesExchangeName>Nasdaq</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>09/08/2020</acquiredDate>
        <natureOfAcquisitionTransaction>Open market purchase</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Open market purchase</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>2500</amountOfSecuritiesAcquired>
        <paymentDate>09/08/2020</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>09/09/2020</acquiredDate>
        <natureOfAcquisitionTransaction>Open market purchase</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Open market purchase</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>2500</amountOfSecuritiesAcquired>
        <paymentDate>09/09/2020</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>09/10/2020</acquiredDate>
        <natureOfAcquisitionTransaction>Open market purchase</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Open market purchase</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>2500</amountOfSecuritiesAcquired>
        <paymentDate>09/10/2020</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>David Dierker</name>
          <address>
            <com:street1>Care of Peoples Bancorp Inc</com:street1>
            <com:street2>138 Putnam Street,  P.O. Box 738</com:street2>
            <com:city>Marietta</com:city>
            <com:stateOrCountry>OH</com:stateOrCountry>
            <com:zipCode>45750</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>09/23/2024</saleDate>
        <amountOfSecuritiesSold>1000</amountOfSecuritiesSold>
        <grossProceeds>30361.94</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>David Dierker</name>
          <address>
            <com:street1>Care of Peoples Bancorp Inc</com:street1>
            <com:street2>138 Putnam Street,  P.O. Box 738</com:street2>
            <com:city>Marietta</com:city>
            <com:stateOrCountry>OH</com:stateOrCountry>
            <com:zipCode>45750</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <saleDate>10/24/2024</saleDate>
        <amountOfSecuritiesSold>1000</amountOfSecuritiesSold>
        <grossProceeds>30992.31</grossProceeds>
      </securitiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>11/26/2024</noticeDate>
        <signature>/s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for David F. Dierker</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 5224}]
text: 144
  0001311548
  XXXXXXXX
  LIVE
  0000318300
  Peoples Bancorp Inc.
  000-16772
  138 Putnam Street
  Marietta
  OH
  45750
  740-373-3155
  David F. Dierker
  Affiliate
  Common
  J.P. Morgan Securities LLC
  390 Madison Avenue - 6th Floor
  New York
  NY
  10017
  7500
  270150
  35508377
  11/26/2024
  Nasdaq
  Common
  09/08/2020
  Open market purchase
  Open market purchase
  N
  2500
  09/08/2020
  Cash
  Common
  09/09/2020
  Open market purchase
  Open market purchase
  N
  2500
  09/09/2020
  Cash
  Common
  09/10/2020
  Open market purchase
  Open market purchase
  N
  2500
  09/10/2020
  Cash
  N
  David Dierker
  Care of Peoples Bancorp Inc
  138 Putnam Street,  P.O. Box 738
  Marietta
  OH
  45750
  Common
  09/23/2024
  1000
  30361.94
  David Dierker
  Care of Peoples Bancorp Inc
  138 Putnam Street,  P.O. Box 738
  Marietta
  OH
  45750
  Common
  10/24/2024
  1000
  30992.31
  11/26/2024
  /s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for David F. Dierker