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      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001860609</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
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      <issuerInfo>
        <issuerCik>0001737953</issuerCik>
        <issuerName>Replimune Group Inc.</issuerName>
        <secFileNumber>001-38596</secFileNumber>
        <issuerAddress>
          <com:street1>500 Unicorn Park Drive</com:street1>
          <com:street2>Suite 303</com:street2>
          <com:city>Woburn</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>01801</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>7812229600</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Sushil Patel</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Chief Strategy  Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>J.P. Morgan Securities LLC</name>
          <address>
            <com:street1>390 Madison Avenue</com:street1>
            <com:street2>6th Floor</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10017</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>15000</noOfUnitsSold>
        <aggregateMarketValue>188550</aggregateMarketValue>
        <noOfUnitsOutstanding>68417444</noOfUnitsOutstanding>
        <approxSaleDate>12/16/2024</approxSaleDate>
        <securitiesExchangeName>Nasdaq</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>05/15/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Rsetricted Stock Units</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>5698</amountOfSecuritiesAcquired>
        <paymentDate>05/15/2022</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>05/15/2023</acquiredDate>
        <natureOfAcquisitionTransaction>Rsetricted Stock Units</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>9302</amountOfSecuritiesAcquired>
        <paymentDate>05/15/2023</paymentDate>
        <natureOfPayment>Compensation</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <noticeSignature>
        <noticeDate>12/16/2024</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>04/03/2024</planAdoptionDate>
        </planAdoptionDates>
        <signature>/s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Sushil Patel</signature>
      </noticeSignature>
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text: 144
  0001860609
  XXXXXXXX
  LIVE
  0001737953
  Replimune Group Inc.
  001-38596
  500 Unicorn Park Drive
  Suite 303
  Woburn
  MA
  01801
  7812229600
  Sushil Patel
  Chief Strategy  Officer
  Common
  J.P. Morgan Securities LLC
  390 Madison Avenue
  6th Floor
  New York
  NY
  10017
  15000
  188550
  68417444
  12/16/2024
  Nasdaq
  Common
  05/15/2022
  Rsetricted Stock Units
  Issuer
  N
  5698
  05/15/2022
  Compensation
  Common
  05/15/2023
  Rsetricted Stock Units
  Issuer
  N
  9302
  05/15/2023
  Compensation
  Y
  12/16/2024
  04/03/2024
  /s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Sushil Patel