content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <!-- Generated by Workiva -->
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001909644</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0000318300</issuerCik>
        <issuerName>Peoples Bancorp Inc.</issuerName>
        <secFileNumber>000-16772</secFileNumber>
        <issuerAddress>
          <com:street1>138 Putnam Street</com:street1>
          <com:city>Marietta</com:city>
          <com:stateOrCountry>OH</com:stateOrCountry>
          <com:zipCode>45750</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>740-373-3155</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Kevin Reeves</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Director</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>J.P. Morgan Securities LLC</name>
          <address>
            <com:street1>390 Madison Avenue - 6th Floor</com:street1>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10017</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>5478</noOfUnitsSold>
        <aggregateMarketValue>168887</aggregateMarketValue>
        <noOfUnitsOutstanding>35645823</noOfUnitsOutstanding>
        <approxSaleDate>05/15/2025</approxSaleDate>
        <securitiesExchangeName>Nasdaq</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>Common</securitiesClassTitle>
        <acquiredDate>03/31/2022</acquiredDate>
        <natureOfAcquisitionTransaction>Compensation</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>5478</amountOfSecuritiesAcquired>
        <paymentDate>03/31/2022</paymentDate>
        <natureOfPayment>NA</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <remarks>This filing is for shares acquired by Kevin Reeves in the form of Executive Stock Compensation from  03/31/2022 - 04/30/2025.</remarks>
      <noticeSignature>
        <noticeDate>05/15/2025</noticeDate>
        <signature>/s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Kevin Reeves.</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 2941}]
text: 144
  0001909644
  XXXXXXXX
  LIVE
  0000318300
  Peoples Bancorp Inc.
  000-16772
  138 Putnam Street
  Marietta
  OH
  45750
  740-373-3155
  Kevin Reeves
  Director
  Common
  J.P. Morgan Securities LLC
  390 Madison Avenue - 6th Floor
  New York
  NY
  10017
  5478
  168887
  35645823
  05/15/2025
  Nasdaq
  Common
  03/31/2022
  Compensation
  Issuer
  N
  5478
  03/31/2022
  NA
  Y
  This filing is for shares acquired by Kevin Reeves in the form of Executive Stock Compensation from  03/31/2022 - 04/30/2025.
  05/15/2025
  /s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Kevin Reeves.