content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001888940</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001591956</issuerCik>
        <issuerName>Sphere 3D Corp.</issuerName>
        <secFileNumber>001-36532</secFileNumber>
        <issuerAddress>
          <com:street1>4 GREENWICH OFFICE PARK</com:street1>
          <com:street2>1ST FLOOR</com:street2>
          <com:city>GREENWICH</com:city>
          <com:stateOrCountry>CT</com:stateOrCountry>
          <com:zipCode>06831</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>416-749-5999</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Trompeter Patricia</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>common</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Oppenheimer &amp; Co Inc</name>
          <address>
            <com:street1>85 Broad Street</com:street1>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10004</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>41858</noOfUnitsSold>
        <aggregateMarketValue>13921.00</aggregateMarketValue>
        <noOfUnitsOutstanding>77266595</noOfUnitsOutstanding>
        <approxSaleDate>05/22/2023</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>common</securitiesClassTitle>
        <acquiredDate>05/22/2023</acquiredDate>
        <natureOfAcquisitionTransaction>RSU</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>41858</amountOfSecuritiesAcquired>
        <paymentDate>05/22/2023</paymentDate>
        <natureOfPayment>FF</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <remarks>POA on File</remarks>
      <noticeSignature>
        <noticeDate>05/22/2023</noticeDate>
        <signature>Patricia Trompeter</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 2765}]
text: 144
  0001888940
  XXXXXXXX
  LIVE
  0001591956
  Sphere 3D Corp.
  001-36532
  4 GREENWICH OFFICE PARK
  1ST FLOOR
  GREENWICH
  CT
  06831
  416-749-5999
  Trompeter Patricia
  Officer
  common
  Oppenheimer & Co Inc
  85 Broad Street
  New York
  NY
  10004
  41858
  13921.00
  77266595
  05/22/2023
  NASDAQ
  common
  05/22/2023
  RSU
  issuer
  N
  41858
  05/22/2023
  FF
  Y
  POA on File
  05/22/2023
  Patricia Trompeter