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            <ccc>XXXXXXXX</ccc>
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        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
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        <issuerName>Galecto, Inc.</issuerName>
        <secFileNumber>001-39655</secFileNumber>
        <issuerAddress>
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          <com:street2>Suite 100</com:street2>
          <com:city>Boston</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>02109</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>45-70-70-52-10</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>The Biotech Growth Trust PLC</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Shareholder</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>Bank of America</name>
          <address>
            <com:street1>One Bryant Park</com:street1>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10036</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>147910</noOfUnitsSold>
        <aggregateMarketValue>91260.00</aggregateMarketValue>
        <noOfUnitsOutstanding>27112697</noOfUnitsOutstanding>
        <approxSaleDate>08/21/2023</approxSaleDate>
        <securitiesExchangeName>Nasdaq Stock Market</securitiesExchangeName>
      </securitiesInformation>
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        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <acquiredDate>09/25/2020</acquiredDate>
        <natureOfAcquisitionTransaction>Private placement</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>147910</amountOfSecuritiesAcquired>
        <paymentDate>09/25/2020</paymentDate>
        <natureOfPayment>Cash</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>The Biotech Growth Trust PLC</name>
          <address>
            <com:street1>601 Lexington Ave.</com:street1>
            <com:street2>54th Floor</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10022</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <saleDate>07/13/2023</saleDate>
        <amountOfSecuritiesSold>14700</amountOfSecuritiesSold>
        <grossProceeds>35280.00</grossProceeds>
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        <sellerDetails>
          <name>The Biotech Growth Trust PLC</name>
          <address>
            <com:street1>601 Lexington Ave.</com:street1>
            <com:street2>54th Floor</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10022</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <saleDate>07/25/2023</saleDate>
        <amountOfSecuritiesSold>8100</amountOfSecuritiesSold>
        <grossProceeds>23652.00</grossProceeds>
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        <sellerDetails>
          <name>The Biotech Growth Trust PLC</name>
          <address>
            <com:street1>601 Lexington Ave.</com:street1>
            <com:street2>54th Floor</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10022</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <saleDate>07/31/2023</saleDate>
        <amountOfSecuritiesSold>40600</amountOfSecuritiesSold>
        <grossProceeds>121800.00</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>The Biotech Growth Trust PLC</name>
          <address>
            <com:street1>601 Lexington Ave.</com:street1>
            <com:street2>54th Floor</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10022</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>Common Stock</securitiesClassTitle>
        <saleDate>08/15/2023</saleDate>
        <amountOfSecuritiesSold>58320</amountOfSecuritiesSold>
        <grossProceeds>43740.00</grossProceeds>
      </securitiesSoldInPast3Months>
      <remarks>OrbiMed Capital LLC is the portfolio manager of The Biotech Growth Trust PLC.</remarks>
      <noticeSignature>
        <noticeDate>08/21/2023</noticeDate>
        <signature>/s/ Douglas Coon, Chief Compliance Officer, OrbiMed Capital LLC, portfolio manager of The Biotech Growth Trust PLC</signature>
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text: 144
  0001157524
  XXXXXXXX
  LIVE
  0001800315
  Galecto, Inc.
  001-39655
  75 State Street
  Suite 100
  Boston
  MA
  02109
  45-70-70-52-10
  The Biotech Growth Trust PLC
  Shareholder
  Common Stock
  Bank of America
  One Bryant Park
  New York
  NY
  10036
  147910
  91260.00
  27112697
  08/21/2023
  Nasdaq Stock Market
  Common Stock
  09/25/2020
  Private placement
  Issuer
  N
  147910
  09/25/2020
  Cash
  N
  The Biotech Growth Trust PLC
  601 Lexington Ave.
  54th Floor
  New York
  NY
  10022
  Common Stock
  07/13/2023
  14700
  35280.00
  The Biotech Growth Trust PLC
  601 Lexington Ave.
  54th Floor
  New York
  NY
  10022
  Common Stock
  07/25/2023
  8100
  23652.00
  The Biotech Growth Trust PLC
  601 Lexington Ave.
  54th Floor
  New York
  NY
  10022
  Common Stock
  07/31/2023
  40600
  121800.00
  The Biotech Growth Trust PLC
  601 Lexington Ave.
  54th Floor
  New York
  NY
  10022
  Common Stock
  08/15/2023
  58320
  43740.00
  OrbiMed Capital LLC is the portfolio manager of The Biotech Growth Trust PLC.
  08/21/2023
  /s/ Douglas Coon, Chief Compliance Officer, OrbiMed Capital LLC, portfolio manager of The Biotech Growth Trust PLC