content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001791115</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001651311</issuerCik>
        <issuerName>Merus N.V.</issuerName>
        <secFileNumber>001-37773</secFileNumber>
        <issuerAddress>
          <com:street1>YALELAAN 62</com:street1>
          <com:city>3584 CM UTRECHT</com:city>
          <com:stateOrCountry>MN</com:stateOrCountry>
          <com:zipCode>3584 CM</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>31 030 253 8800</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Shuman Harry</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>COMMON</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>RBC WEALTH MANAGEMENT</name>
          <address>
            <com:street1>250 NICOLLET MALL, SUITE 1700</com:street1>
            <com:city>MINNEAPOLIS</com:city>
            <com:stateOrCountry>MN</com:stateOrCountry>
            <com:zipCode>55401</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>575</noOfUnitsSold>
        <aggregateMarketValue>14133.00</aggregateMarketValue>
        <noOfUnitsOutstanding>57732814</noOfUnitsOutstanding>
        <approxSaleDate>12/01/2023</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>COMMON</securitiesClassTitle>
        <acquiredDate>12/01/2023</acquiredDate>
        <natureOfAcquisitionTransaction>RSU VEST</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>575</amountOfSecuritiesAcquired>
        <paymentDate>12/01/2023</paymentDate>
        <natureOfPayment>COMPENSATON</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <remarks>SOLD PURSUANT TO A RULE 10B5-1 PLAN ESTABLISHED 03/24/22</remarks>
      <noticeSignature>
        <noticeDate>12/01/2023</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>03/24/2022</planAdoptionDate>
        </planAdoptionDates>
        <signature>JEFFREY EISCHENS</signature>
      </noticeSignature>
    </formData>
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 2884}]
text: 144
  0001791115
  XXXXXXXX
  LIVE
  0001651311
  Merus N.V.
  001-37773
  YALELAAN 62
  3584 CM UTRECHT
  MN
  3584 CM
  31 030 253 8800
  Shuman Harry
  Officer
  COMMON
  RBC WEALTH MANAGEMENT
  250 NICOLLET MALL, SUITE 1700
  MINNEAPOLIS
  MN
  55401
  575
  14133.00
  57732814
  12/01/2023
  NASDAQ
  COMMON
  12/01/2023
  RSU VEST
  ISSUER
  N
  575
  12/01/2023
  COMPENSATON
  Y
  SOLD PURSUANT TO A RULE 10B5-1 PLAN ESTABLISHED 03/24/22
  12/01/2023
  03/24/2022
  JEFFREY EISCHENS