content: <?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
    <headerData>
      <submissionType>144</submissionType>
      <filerInfo>
        <filer>
          <filerCredentials>
            <cik>0001790314</cik>
            <ccc>XXXXXXXX</ccc>
          </filerCredentials>
        </filer>
        <liveTestFlag>LIVE</liveTestFlag>
  
  
  
      </filerInfo>
    </headerData>
    <formData>
      <issuerInfo>
        <issuerCik>0001651311</issuerCik>
        <issuerName>Merus N.V.</issuerName>
        <secFileNumber>001-37773</secFileNumber>
        <issuerAddress>
          <com:street1>YALELAAN 62</com:street1>
          <com:city>3584 CM UTRECHT</com:city>
          <com:stateOrCountry>P7</com:stateOrCountry>
          <com:zipCode>3584 CM</com:zipCode>
        </issuerAddress>
        <issuerContactPhone>31 030 253 8800</issuerContactPhone>
        <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Silverman Peter B.</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
        <relationshipsToIssuer>
          <relationshipToIssuer>Officer</relationshipToIssuer>
        </relationshipsToIssuer>
      </issuerInfo>
      <securitiesInformation>
        <securitiesClassTitle>COMMON</securitiesClassTitle>
        <brokerOrMarketmakerDetails>
          <name>RBC CAPITALS MARKETS LLC</name>
          <address>
            <com:street1>250 Nicollet Mall</com:street1>
            <com:street2>Suite 1700</com:street2>
            <com:city>Minneapolis</com:city>
            <com:stateOrCountry>MN</com:stateOrCountry>
            <com:zipCode>55401</com:zipCode>
          </address>
        </brokerOrMarketmakerDetails>
        <noOfUnitsSold>16805</noOfUnitsSold>
        <aggregateMarketValue>924313.00</aggregateMarketValue>
        <noOfUnitsOutstanding>69213576</noOfUnitsOutstanding>
        <approxSaleDate>07/10/2025</approxSaleDate>
        <securitiesExchangeName>NASDAQ</securitiesExchangeName>
      </securitiesInformation>
      <securitiesToBeSold>
        <securitiesClassTitle>COMMON</securitiesClassTitle>
        <acquiredDate>07/10/2025</acquiredDate>
        <natureOfAcquisitionTransaction>STOCK OPTION EXERCISE</natureOfAcquisitionTransaction>
        <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
        <isGiftTransaction>N</isGiftTransaction>
        <amountOfSecuritiesAcquired>16805</amountOfSecuritiesAcquired>
        <paymentDate>07/10/2025</paymentDate>
        <natureOfPayment>CHECK</natureOfPayment>
      </securitiesToBeSold>
      <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>PETER SILVERMAN C/O RBC CAPITAL MARKETS LLC</name>
          <address>
            <com:street1>250 NICOLLET MALL</com:street1>
            <com:street2>SUITE 1700</com:street2>
            <com:city>MINNEAPOLIS</com:city>
            <com:stateOrCountry>MN</com:stateOrCountry>
            <com:zipCode>55401</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>COMMON</securitiesClassTitle>
        <saleDate>06/20/2025</saleDate>
        <amountOfSecuritiesSold>34000</amountOfSecuritiesSold>
        <grossProceeds>1793741.00</grossProceeds>
      </securitiesSoldInPast3Months>
      <securitiesSoldInPast3Months>
        <sellerDetails>
          <name>PETER SILVERMAN C/O RBC CAPITAL MARKETS LLC</name>
          <address>
            <com:street1>250 NICOLLET MALL</com:street1>
            <com:street2>SUITE 1700</com:street2>
            <com:city>MINNEAPOLIS</com:city>
            <com:stateOrCountry>MN</com:stateOrCountry>
            <com:zipCode>55401</com:zipCode>
          </address>
        </sellerDetails>
        <securitiesClassTitle>COMMON</securitiesClassTitle>
        <saleDate>07/09/2025</saleDate>
        <amountOfSecuritiesSold>6695</amountOfSecuritiesSold>
        <grossProceeds>368240.00</grossProceeds>
      </securitiesSoldInPast3Months>
      <remarks>SOLD PURSUANT TO RULE 10B5-1 PLAN ESTABLISHED 3-20-2025</remarks>
      <noticeSignature>
        <noticeDate>07/10/2025</noticeDate>
        <planAdoptionDates>
          <planAdoptionDate>03/20/2025</planAdoptionDate>
        </planAdoptionDates>
        <signature>POA JEFFREY J. KAPALA</signature>
      </noticeSignature>
    </formData>
  
  </edgarSubmission>
metadata_documents: [{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 4272}]
text: 144
  0001790314
  XXXXXXXX
  LIVE
  0001651311
  Merus N.V.
  001-37773
  YALELAAN 62
  3584 CM UTRECHT
  P7
  3584 CM
  31 030 253 8800
  Silverman Peter B.
  Officer
  COMMON
  RBC CAPITALS MARKETS LLC
  250 Nicollet Mall
  Suite 1700
  Minneapolis
  MN
  55401
  16805
  924313.00
  69213576
  07/10/2025
  NASDAQ
  COMMON
  07/10/2025
  STOCK OPTION EXERCISE
  ISSUER
  N
  16805
  07/10/2025
  CHECK
  N
  PETER SILVERMAN C/O RBC CAPITAL MARKETS LLC
  250 NICOLLET MALL
  SUITE 1700
  MINNEAPOLIS
  MN
  55401
  COMMON
  06/20/2025
  34000
  1793741.00
  PETER SILVERMAN C/O RBC CAPITAL MARKETS LLC
  250 NICOLLET MALL
  SUITE 1700
  MINNEAPOLIS
  MN
  55401
  COMMON
  07/09/2025
  6695
  368240.00
  SOLD PURSUANT TO RULE 10B5-1 PLAN ESTABLISHED 3-20-2025
  07/10/2025
  03/20/2025
  POA JEFFREY J. KAPALA