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            <filer>
                <filerCredentials>
                    <cik>0002012715</cik>
                    <ccc>XXXXXXXX</ccc>
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            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



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        <issuerInfo>
            <issuerCik>0001393434</issuerCik>
            <issuerName>OCULAR THERAPEUTIX, INC.</issuerName>
            <secFileNumber>001-36554</secFileNumber>
            <issuerAddress>
                <ns2:street1>15 Crosby Drive</ns2:street1>
                <ns2:city>Bedford</ns2:city>
                <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                <ns2:zipCode>01730</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>781-357-4000</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>SANJAY NAYAK</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>1862</noOfUnitsSold>
            <aggregateMarketValue>13346.82</aggregateMarketValue>
            <noOfUnitsOutstanding>159299736</noOfUnitsOutstanding>
            <approxSaleDate>05/23/2025</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>05/22/2025</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>1862</amountOfSecuritiesAcquired>
            <paymentDate>02/22/2025</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>SANJAY NAYAK</name>
                <address>
                    <ns2:street1>15 Crosby Drive</ns2:street1>
                    <ns2:city>Bedford</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>01730</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>02/24/2025</saleDate>
            <amountOfSecuritiesSold>1895</amountOfSecuritiesSold>
            <grossProceeds>12956.68</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>05/23/2025</noticeDate>
            <planAdoptionDates/>
            <signature>/s/ Sanjay Nayak</signature>
        </noticeSignature>
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144
0002012715
XXXXXXXX
LIVE
0001393434
OCULAR THERAPEUTIX, INC.
001-36554
15 Crosby Drive
Bedford
MA
01730
781-357-4000
SANJAY NAYAK
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
1862
13346.82
159299736
05/23/2025
NASDAQ
Common
05/22/2025
Restricted stock vesting under a registered plan
ISSUER
N
1862
02/22/2025
Cash
N
SANJAY NAYAK
15 Crosby Drive
Bedford
MA
01730
Common
02/24/2025
1895
12956.68
05/23/2025
/s/ Sanjay Nayak