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            <filer>
                <filerCredentials>
                    <cik>0001697362</cik>
                    <ccc>XXXXXXXX</ccc>
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            <liveTestFlag>LIVE</liveTestFlag>



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        <issuerInfo>
            <issuerCik>0001604821</issuerCik>
            <issuerName>NATERA INC</issuerName>
            <secFileNumber>001-37478</secFileNumber>
            <issuerAddress>
                <ns2:street1>13011 McCallen Pass</ns2:street1>
                <ns2:city>Austin</ns2:city>
                <ns2:stateOrCountry>TX</ns2:stateOrCountry>
                <ns2:zipCode>78753</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>6509809190</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>MICHAEL BURKES BROPHY</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>920</noOfUnitsSold>
            <aggregateMarketValue>129379.60</aggregateMarketValue>
            <noOfUnitsOutstanding>136546580</noOfUnitsOutstanding>
            <approxSaleDate>07/22/2025</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>07/20/2025</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>920</amountOfSecuritiesAcquired>
            <paymentDate>07/20/2025</paymentDate>
            <natureOfPayment>N/A</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
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            <sellerDetails>
                <name>10b5-1 Sales Plan for MICHAEL BURKES BROPHY</name>
                <address>
                    <ns2:street1>13011 McCallen Pass</ns2:street1>
                    <ns2:city>Austin</ns2:city>
                    <ns2:stateOrCountry>TX</ns2:stateOrCountry>
                    <ns2:zipCode>78753</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>04/29/2025</saleDate>
            <amountOfSecuritiesSold>3045</amountOfSecuritiesSold>
            <grossProceeds>469483.58</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales Plan for MICHAEL BURKES BROPHY</name>
                <address>
                    <ns2:street1>13011 McCallen Pass</ns2:street1>
                    <ns2:city>Austin</ns2:city>
                    <ns2:stateOrCountry>TX</ns2:stateOrCountry>
                    <ns2:zipCode>78753</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>04/24/2025</saleDate>
            <amountOfSecuritiesSold>755</amountOfSecuritiesSold>
            <grossProceeds>115101.71</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>MICHAEL BURKES BROPHY</name>
                <address>
                    <ns2:street1>13011 McCallen Pass</ns2:street1>
                    <ns2:city>Austin</ns2:city>
                    <ns2:stateOrCountry>TX</ns2:stateOrCountry>
                    <ns2:zipCode>78753</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>04/23/2025</saleDate>
            <amountOfSecuritiesSold>495</amountOfSecuritiesSold>
            <grossProceeds>74616.30</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>07/22/2025</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>06/14/2024</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Michael Burkes Brophy</signature>
        </noticeSignature>
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144
0001697362
XXXXXXXX
LIVE
0001604821
NATERA INC
001-37478
13011 McCallen Pass
Austin
TX
78753
6509809190
MICHAEL BURKES BROPHY
Officer
COMMON
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
920
129379.60
136546580
07/22/2025
NASDAQ
Common
07/20/2025
Restricted Stock Units
Issuer
N
920
07/20/2025
N/A
N
10b5-1 Sales Plan for MICHAEL BURKES BROPHY
13011 McCallen Pass
Austin
TX
78753
COMMON
04/29/2025
3045
469483.58
10b5-1 Sales Plan for MICHAEL BURKES BROPHY
13011 McCallen Pass
Austin
TX
78753
COMMON
04/24/2025
755
115101.71
MICHAEL BURKES BROPHY
13011 McCallen Pass
Austin
TX
78753
Common
04/23/2025
495
74616.30
07/22/2025
06/14/2024
/s/ Michael Burkes Brophy