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                <ns2:street2>4th Floor</ns2:street2>
                <ns2:city>Watertown</ns2:city>
                <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                <ns2:zipCode>02472</ns2:zipCode>
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            <relationshipsToIssuer>
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            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
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            <natureOfAcquisitionTransaction>Stock Option Exercise</natureOfAcquisitionTransaction>
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            <isGiftTransaction>N</isGiftTransaction>
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            <paymentDate>08/26/2024</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
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                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02472</ns2:zipCode>
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                    <ns2:zipCode>02472</ns2:zipCode>
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            <securitiesClassTitle>Common</securitiesClassTitle>
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            <grossProceeds>619657.78</grossProceeds>
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            <securitiesClassTitle>Common</securitiesClassTitle>
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            <grossProceeds>150105.29</grossProceeds>
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                    <ns2:zipCode>02472</ns2:zipCode>
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        <securitiesSoldInPast3Months>
            <sellerDetails>
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                    <ns2:zipCode>02472</ns2:zipCode>
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            <saleDate>07/23/2024</saleDate>
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        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>08/26/2024</noticeDate>
            <planAdoptionDates/>
            <signature>/s/ Joanna C Horobin</signature>
        </noticeSignature>
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144
0001560959
XXXXXXXX
LIVE
0001815442
KYMERA THERAPEUTICS, INC.
001-39460
500 North Beacon Street
4th Floor
Watertown
MA
02472
(857) 285-5300
JOANNA HOROBIN
Director
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
12000
589896.00
61753243
08/26/2024
NASDAQ
Common
08/26/2024
Stock Option Exercise
Issuer
N
12000
08/26/2024
Cash
N
JOANNA HOROBIN
500 North Beacon Street
4th Floor
Watertown
MA
02472
Common
08/05/2024
11944
476262.22
JOANNA HOROBIN
500 North Beacon Street
4th Floor
Watertown
MA
02472
Common
08/02/2024
10000
413708.00
JOANNA HOROBIN
500 North Beacon Street
4th Floor
Watertown
MA
02472
Common
08/01/2024
13819
619657.78
JOANNA HOROBIN
500 North Beacon Street
4th Floor
Watertown
MA
02472
Common
07/31/2024
9342
426224.08
JOANNA HOROBIN
500 North Beacon Street
4th Floor
Watertown
MA
02472
Common
07/30/2024
300
13219.98
JOANNA HOROBIN
500 North Beacon Street
4th Floor
Watertown
MA
02472
Common
07/29/2024
3358
150105.29
JOANNA HOROBIN
500 North Beacon Street
4th Floor
Watertown
MA
02472
Common
07/26/2024
8195
368305.43
JOANNA HOROBIN
500 North Beacon Street
4th Floor
Watertown
MA
02472
Common
07/25/2024
10000
445776.00
JOANNA HOROBIN
500 North Beacon Street
4th Floor
Watertown
MA
02472
Common
07/23/2024
15000
648841.00
JOANNA HOROBIN
500 North Beacon Street
4th Floor
Watertown
MA
02472
Common
06/07/2024
8500
280399.70
08/26/2024
/s/ Joanna C Horobin