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        <com:stateOrCountry>MA</com:stateOrCountry>
        <com:zipCode>02451</com:zipCode>
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      <issuerContactPhone>857-399-9500</issuerContactPhone>
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        <address>
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          <com:city>Westlake</com:city>
          <com:stateOrCountry>TX</com:stateOrCountry>
          <com:zipCode>76262</com:zipCode>
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    <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <noticeSignature>
      <noticeDate>05/15/2023</noticeDate>
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144
0001251553
XXXXXXXX
LIVE
0001783328
TScan Therapeutics, Inc.
001-40603
830 WINTER STREET
WALTHAM
MA
02451
857-399-9500
SOUTHWELL DAVID P
Director
Common
Charles Schwab Company
3000 Schwab Way
Westlake
TX
76262
85911
346221.00
19480729
05/15/2023
Nasdaq
Common
09/08/2021
Open Market
Open Market
N
12237
09/08/2021
Cash
Common
03/02/2022
Exercised Stock Options
Issuer
N
48670
03/04/2022
Compensation
Common
05/18/2022
Open Market
Open Market
N
25004
05/18/2022
Cash
Y
05/15/2023
David Peabody Southwell