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        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001286090</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001039065</issuerCik>
            <issuerName>OSI SYSTEMS INC</issuerName>
            <secFileNumber>000-23125</secFileNumber>
            <issuerAddress>
                <ns2:street1>12525 Chadron Avenue</ns2:street1>
                <ns2:city>Hawthorne</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>90250</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>310-978-0516</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>VICTOR SO-MIEN SZE &amp;ANGELA HSIN-CHI HSU CO-TTEESZE TRUST U/T/A DTD 11/25/2014</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>38th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>10000</noOfUnitsSold>
            <aggregateMarketValue>1218667.00</aggregateMarketValue>
            <noOfUnitsOutstanding>16727882</noOfUnitsOutstanding>
            <approxSaleDate>06/02/2023</approxSaleDate>
            <securitiesExchangeName>NASD</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>06/03/2011</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>3371</amountOfSecuritiesAcquired>
            <paymentDate>06/03/2011</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>12/29/2017</acquiredDate>
            <natureOfAcquisitionTransaction>Shares Purchased through Employee Stock Purchase Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>214</amountOfSecuritiesAcquired>
            <paymentDate>12/29/2017</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>06/30/2016</acquiredDate>
            <natureOfAcquisitionTransaction>Shares Purchased through Employee Stock Purchase Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>201</amountOfSecuritiesAcquired>
            <paymentDate>06/30/2016</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>06/29/2018</acquiredDate>
            <natureOfAcquisitionTransaction>Shares Purchased through Employee Stock Purchase Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>214</amountOfSecuritiesAcquired>
            <paymentDate>06/29/2018</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>02/08/2011</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>625</amountOfSecuritiesAcquired>
            <paymentDate>02/08/2011</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>05/17/2012</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>575</amountOfSecuritiesAcquired>
            <paymentDate>05/17/2012</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>06/28/2019</acquiredDate>
            <natureOfAcquisitionTransaction>Shares Purchased through Employee Stock Purchase Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>173</amountOfSecuritiesAcquired>
            <paymentDate>06/28/2019</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>06/28/2013</acquiredDate>
            <natureOfAcquisitionTransaction>Shares Purchased through Employee Stock Purchase Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>191</amountOfSecuritiesAcquired>
            <paymentDate>06/28/2013</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>02/08/2012</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>625</amountOfSecuritiesAcquired>
            <paymentDate>02/08/2012</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>09/30/2014</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>194</amountOfSecuritiesAcquired>
            <paymentDate>09/30/2014</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>12/31/2014</acquiredDate>
            <natureOfAcquisitionTransaction>Shares Purchased through Employee Stock Purchase Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>127</amountOfSecuritiesAcquired>
            <paymentDate>12/31/2014</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>06/30/2015</acquiredDate>
            <natureOfAcquisitionTransaction>Shares Purchased through Employee Stock Purchase Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>201</amountOfSecuritiesAcquired>
            <paymentDate>06/30/2015</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>12/31/2015</acquiredDate>
            <natureOfAcquisitionTransaction>Shares Purchased through Employee Stock Purchase Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>201</amountOfSecuritiesAcquired>
            <paymentDate>12/30/2016</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>12/30/2016</acquiredDate>
            <natureOfAcquisitionTransaction>Shares Purchased through Employee Stock Purchase Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>214</amountOfSecuritiesAcquired>
            <paymentDate>12/30/2016</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>12/31/2018</acquiredDate>
            <natureOfAcquisitionTransaction>Shares Purchased through Employee Stock Purchase Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>160</amountOfSecuritiesAcquired>
            <paymentDate>12/31/2018</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>09/01/2011</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>2500</amountOfSecuritiesAcquired>
            <paymentDate>09/01/2011</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>06/30/2017</acquiredDate>
            <natureOfAcquisitionTransaction>Shares Purchased through Employee Stock Purchase Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>214</amountOfSecuritiesAcquired>
            <paymentDate>06/30/2017</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>Victor Sze</name>
                <address>
                    <ns2:street1>12525 Chadron Avenue</ns2:street1>
                    <ns2:city>Hawthorne</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>90250</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>RSU</securitiesClassTitle>
            <saleDate>05/08/2023</saleDate>
            <amountOfSecuritiesSold>20000</amountOfSecuritiesSold>
            <grossProceeds>2353998.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>06/02/2023</noticeDate>
            <planAdoptionDates/>
            <signature>/s/ Victor So-Mien Sze</signature>
        </noticeSignature>
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144
0001286090
XXXXXXXX
LIVE
0001039065
OSI SYSTEMS INC
000-23125
12525 Chadron Avenue
Hawthorne
CA
90250
310-978-0516
VICTOR SO-MIEN SZE &ANGELA HSIN-CHI HSU CO-TTEESZE TRUST U/T/A DTD 11/25/2014
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
38th Floor
New York
NY
10004
10000
1218667.00
16727882
06/02/2023
NASD
Common
06/03/2011
Restricted stock vesting under a registered plan
Issuer
N
3371
06/03/2011
Not Applicable
Common
12/29/2017
Shares Purchased through Employee Stock Purchase Plan
Issuer
N
214
12/29/2017
Cash
Common
06/30/2016
Shares Purchased through Employee Stock Purchase Plan
Issuer
N
201
06/30/2016
Cash
Common
06/29/2018
Shares Purchased through Employee Stock Purchase Plan
Issuer
N
214
06/29/2018
Cash
Common
02/08/2011
Restricted stock vesting under a registered plan
Issuer
N
625
02/08/2011
Not Applicable
Common
05/17/2012
Restricted stock vesting under a registered plan
Issuer
N
575
05/17/2012
Not Applicable
Common
06/28/2019
Shares Purchased through Employee Stock Purchase Plan
Issuer
N
173
06/28/2019
Cash
Common
06/28/2013
Shares Purchased through Employee Stock Purchase Plan
Issuer
N
191
06/28/2013
Cash
Common
02/08/2012
Restricted stock vesting under a registered plan
Issuer
N
625
02/08/2012
Not Applicable
Common
09/30/2014
Restricted stock vesting under a registered plan
Issuer
N
194
09/30/2014
Not Applicable
Common
12/31/2014
Shares Purchased through Employee Stock Purchase Plan
Issuer
N
127
12/31/2014
Cash
Common
06/30/2015
Shares Purchased through Employee Stock Purchase Plan
Issuer
N
201
06/30/2015
Cash
Common
12/31/2015
Shares Purchased through Employee Stock Purchase Plan
Issuer
N
201
12/30/2016
Cash
Common
12/30/2016
Shares Purchased through Employee Stock Purchase Plan
Issuer
N
214
12/30/2016
Cash
Common
12/31/2018
Shares Purchased through Employee Stock Purchase Plan
Issuer
N
160
12/31/2018
Cash
Common
09/01/2011
Restricted stock vesting under a registered plan
Issuer
N
2500
09/01/2011
Not Applicable
Common
06/30/2017
Shares Purchased through Employee Stock Purchase Plan
Issuer
N
214
06/30/2017
Cash
N
Victor Sze
12525 Chadron Avenue
Hawthorne
CA
90250
RSU
05/08/2023
20000
2353998.00
06/02/2023
/s/ Victor So-Mien Sze