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      <filer>
        <filerCredentials>
          <cik>0001365306</cik>
          <ccc>XXXXXXXX</ccc>
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      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
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    <issuerInfo>
      <issuerCik>0000318154</issuerCik>
      <issuerName>AMGEN INC</issuerName>
      <secFileNumber>001-37702</secFileNumber>
      <issuerAddress>
        <com:street1>ONE AMGEN CENTER DRIVE</com:street1>
        <com:city>THOUSAND OAKS</com:city>
        <com:stateOrCountry>CA</com:stateOrCountry>
        <com:zipCode>91320</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>(805)447-1000</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Graham Jonathan P</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Officer</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Charles Schwab Corp.</name>
        <address>
          <com:street1>3000 Schwab Way</com:street1>
          <com:city>Westlake</com:city>
          <com:stateOrCountry>TX</com:stateOrCountry>
          <com:zipCode>76262</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>25045</noOfUnitsSold>
      <aggregateMarketValue>7336682.00</aggregateMarketValue>
      <noOfUnitsOutstanding>537532723</noOfUnitsOutstanding>
      <approxSaleDate>02/07/2025</approxSaleDate>
      <securitiesExchangeName>Nasdaq</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <acquiredDate>02/07/2025</acquiredDate>
      <natureOfAcquisitionTransaction>Stock Option Exercise</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer: Amgen Inc.</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>25045</amountOfSecuritiesAcquired>
      <paymentDate>02/07/2025</paymentDate>
      <natureOfPayment>Broker's Check</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <remarks>Trade placed in account registered: Jonathan Park Graham TTEE The Graham-Ulmer Family Trust</remarks>
    <noticeSignature>
      <noticeDate>02/07/2025</noticeDate>
      <signature>Jonathan Graham</signature>
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144
0001365306
XXXXXXXX
LIVE
0000318154
AMGEN INC
001-37702
ONE AMGEN CENTER DRIVE
THOUSAND OAKS
CA
91320
(805)447-1000
Graham Jonathan P
Officer
Common
Charles Schwab Corp.
3000 Schwab Way
Westlake
TX
76262
25045
7336682.00
537532723
02/07/2025
Nasdaq
Common
02/07/2025
Stock Option Exercise
Issuer: Amgen Inc.
N
25045
02/07/2025
Broker's Check
Y
Trade placed in account registered: Jonathan Park Graham TTEE The Graham-Ulmer Family Trust
02/07/2025
Jonathan Graham