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                <ns2:city>Research Triangle Park</ns2:city>
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                    <ns2:street1>3 EDISON DRIVE</ns2:street1>
                    <ns2:city>ALPHARETTA</ns2:city>
                    <ns2:stateOrCountry>GA</ns2:stateOrCountry>
                    <ns2:zipCode>30005</ns2:zipCode>
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            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
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                    <ns2:stateOrCountry>NC</ns2:stateOrCountry>
                    <ns2:zipCode>27709</ns2:zipCode>
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                    <ns2:stateOrCountry>NC</ns2:stateOrCountry>
                    <ns2:zipCode>27709</ns2:zipCode>
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            <amountOfSecuritiesSold>2207</amountOfSecuritiesSold>
            <grossProceeds>18692.00</grossProceeds>
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        <noticeSignature>
            <noticeDate>08/18/2023</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>03/18/2022</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Chris Anigeron Rallis</signature>
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144
0001185945
XXXXXXXX
LIVE
0001211583
FENNEC PHARMACEUTICALS INC.
001-32295
PO BOX 13628, 68 TW ALEXANDER DRIVE
Research Triangle Park
NC
27709
(919) 636-4530
CHRIS A RALLIS
Director
Common
E*TRADE FINANCIAL CORPORATION
3 EDISON DRIVE
ALPHARETTA
GA
30005
673
5283.05
26566467
08/18/2023
NASDAQ
COMMON
07/18/2022
Exercised Shares
ISSUER
N
673
07/18/2022
Cash
N
CHRIS A RALLIS
PO BOX 13628, 68 TW ALEXANDER DRIVE
Research Triangle Park
NC
27709
Common
07/24/2023
6796
55549.82
CHRIS A RALLIS
PO BOX 13628, 68 TW ALEXANDER DRIVE
Research Triangle Park
NC
27709
Common
05/19/2023
1758
12938.88
CHRIS A RALLIS
PO BOX 13628, 68 TW ALEXANDER DRIVE
Research Triangle Park
NC
27709
Common
07/06/2023
2207
18692.00
08/18/2023
03/18/2022
/s/ Chris Anigeron Rallis