<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001492695</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0000842023</issuerCik>
      <issuerName>BIO-TECHNE Corp</issuerName>
      <secFileNumber>000-17272</secFileNumber>
      <issuerAddress>
        <com:street1>614 MCKINLEY PL N E</com:street1>
        <com:city>MINNEAPOLIS</com:city>
        <com:stateOrCountry>MN</com:stateOrCountry>
        <com:zipCode>55413</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>6123798854</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Nusse Roeland</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Director</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Charles Schwab Corp.</name>
        <address>
          <com:street1>3000 Schwab Way</com:street1>
          <com:city>Westlake</com:city>
          <com:stateOrCountry>TX</com:stateOrCountry>
          <com:zipCode>76262</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>10400</noOfUnitsSold>
      <aggregateMarketValue>800626.00</aggregateMarketValue>
      <noOfUnitsOutstanding>157191685</noOfUnitsOutstanding>
      <approxSaleDate>03/07/2024</approxSaleDate>
      <securitiesExchangeName>Nasdaq</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Commone</securitiesClassTitle>
      <acquiredDate>10/02/2019</acquiredDate>
      <natureOfAcquisitionTransaction>Stock Option Exercise and Stock Dividends</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>10400</amountOfSecuritiesAcquired>
      <paymentDate>10/19/2019</paymentDate>
      <natureOfPayment>Cash</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <remarks>Client exercised Stock Options on 10/02/2019, and received quarterly dividends in the form of stock between 10/2/2019 thru 3/1/2021 Client is selling from an account registered: Roeland Nusse and Elizabeth Mathews TTEEs The Nusse-Mathews Living Trust</remarks>
    <noticeSignature>
      <noticeDate>03/07/2024</noticeDate>
      <signature>Roeland Nusse</signature>
    </noticeSignature>
  </formData>
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144
0001492695
XXXXXXXX
LIVE
0000842023
BIO-TECHNE Corp
000-17272
614 MCKINLEY PL N E
MINNEAPOLIS
MN
55413
6123798854
Nusse Roeland
Director
Common
Charles Schwab Corp.
3000 Schwab Way
Westlake
TX
76262
10400
800626.00
157191685
03/07/2024
Nasdaq
Commone
10/02/2019
Stock Option Exercise and Stock Dividends
Issuer
N
10400
10/19/2019
Cash
Y
Client exercised Stock Options on 10/02/2019, and received quarterly dividends in the form of stock between 10/2/2019 thru 3/1/2021 Client is selling from an account registered: Roeland Nusse and Elizabeth Mathews TTEEs The Nusse-Mathews Living Trust
03/07/2024
Roeland Nusse