<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001648518</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0001069183</issuerCik>
      <issuerName>AXON ENTERPRISE, INC.</issuerName>
      <secFileNumber>001-16391</secFileNumber>
      <issuerAddress>
        <com:street1>17800 N. 85TH ST.</com:street1>
        <com:city>SCOTTSDALE</com:city>
        <com:stateOrCountry>AZ</com:stateOrCountry>
        <com:zipCode>85255</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>480-991-0797</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Isner Joshua</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Officer</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Wells Faro Clearing Services</name>
        <address>
          <com:street1>1 N. Jefferson Ave. </com:street1>
          <com:city>St. Louis</com:city>
          <com:stateOrCountry>MO</com:stateOrCountry>
          <com:zipCode>63103</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>20000</noOfUnitsSold>
      <aggregateMarketValue>12122116.67</aggregateMarketValue>
      <noOfUnitsOutstanding>76254776</noOfUnitsOutstanding>
      <approxSaleDate>11/12/2024</approxSaleDate>
      <securitiesExchangeName>Nasdaq</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <acquiredDate>05/18/2023</acquiredDate>
      <natureOfAcquisitionTransaction>Compensation</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>20000</amountOfSecuritiesAcquired>
      <paymentDate>05/18/2023</paymentDate>
      <natureOfPayment>N/A</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Joshua Isner</name>
        <address>
          <com:street1>17800 N. 85th St.</com:street1>
          <com:city>Scottsdale</com:city>
          <com:stateOrCountry>AZ</com:stateOrCountry>
          <com:zipCode>85255</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common Stock </securitiesClassTitle>
      <saleDate>09/10/2024</saleDate>
      <amountOfSecuritiesSold>5874</amountOfSecuritiesSold>
      <grossProceeds>2117897.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Joshua Isner</name>
        <address>
          <com:street1>17800 N. 85th St.</com:street1>
          <com:city>Scottsdale,</com:city>
          <com:stateOrCountry>AZ</com:stateOrCountry>
          <com:zipCode>85255</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <saleDate>09/10/2024</saleDate>
      <amountOfSecuritiesSold>19937</amountOfSecuritiesSold>
      <grossProceeds>7170039.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <remarks>Shares being sold from Stool and Stars Revocable Trust, Joshua Isner is a Trustee of the trust and is an officer of VECO. </remarks>
    <noticeSignature>
      <noticeDate>11/12/2024</noticeDate>
      <signature>Joshua Isner</signature>
    </noticeSignature>
  </formData>
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144
0001648518
XXXXXXXX
LIVE
0001069183
AXON ENTERPRISE, INC.
001-16391
17800 N. 85TH ST.
SCOTTSDALE
AZ
85255
480-991-0797
Isner Joshua
Officer
Common
Wells Faro Clearing Services
1 N. Jefferson Ave.
St. Louis
MO
63103
20000
12122116.67
76254776
11/12/2024
Nasdaq
Common
05/18/2023
Compensation
Issuer
N
20000
05/18/2023
N/A
N
Joshua Isner
17800 N. 85th St.
Scottsdale
AZ
85255
Common Stock
09/10/2024
5874
2117897.00
Joshua Isner
17800 N. 85th St.
Scottsdale,
AZ
85255
Common Stock
09/10/2024
19937
7170039.00
Shares being sold from Stool and Stars Revocable Trust, Joshua Isner is a Trustee of the trust and is an officer of VECO.
11/12/2024
Joshua Isner