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            <liveTestFlag>LIVE</liveTestFlag>



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            <secFileNumber>001-32335</secFileNumber>
            <issuerAddress>
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                <ns2:city>San Diego</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>92130</ns2:zipCode>
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            <issuerContactPhone>(858) 794-8889</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>MICHAEL LABARRE</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
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        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>10000</noOfUnitsSold>
            <aggregateMarketValue>551145.00</aggregateMarketValue>
            <noOfUnitsOutstanding>127274000</noOfUnitsOutstanding>
            <approxSaleDate>07/24/2024</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
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            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <acquiredDate>07/24/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Stock Option Exercise</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>10000</amountOfSecuritiesAcquired>
            <paymentDate>07/24/2024</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
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                <address>
                    <ns2:street1>12390 El Camino Real</ns2:street1>
                    <ns2:city>San Diego</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>92130</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>07/23/2024</saleDate>
            <amountOfSecuritiesSold>10000</amountOfSecuritiesSold>
            <grossProceeds>548872.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>MICHAEL LABARRE</name>
                <address>
                    <ns2:street1>12390 El Camino Real</ns2:street1>
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                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>92130</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>06/18/2024</saleDate>
            <amountOfSecuritiesSold>10000</amountOfSecuritiesSold>
            <grossProceeds>494262.00</grossProceeds>
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        <securitiesSoldInPast3Months>
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                    <ns2:zipCode>92130</ns2:zipCode>
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            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>05/22/2024</saleDate>
            <amountOfSecuritiesSold>10000</amountOfSecuritiesSold>
            <grossProceeds>453835.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>MICHAEL LABARRE</name>
                <address>
                    <ns2:street1>12390 El Camino Real</ns2:street1>
                    <ns2:city>San Diego</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>92130</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>05/21/2024</saleDate>
            <amountOfSecuritiesSold>10000</amountOfSecuritiesSold>
            <grossProceeds>451635.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>07/24/2024</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>03/09/2023</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Michael James LaBarre</signature>
        </noticeSignature>
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144
0001507174
XXXXXXXX
LIVE
0001159036
HALOZYME THERAPEUTICS, INC.
001-32335
12390 El Camino Real
San Diego
CA
92130
(858) 794-8889
MICHAEL LABARRE
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
10000
551145.00
127274000
07/24/2024
NASDAQ
COMMON
07/24/2024
Stock Option Exercise
ISSUER
N
10000
07/24/2024
Cash
N
MICHAEL LABARRE
12390 El Camino Real
San Diego
CA
92130
Common
07/23/2024
10000
548872.00
MICHAEL LABARRE
12390 El Camino Real
San Diego
CA
92130
Common
06/18/2024
10000
494262.00
MICHAEL LABARRE
12390 El Camino Real
San Diego
CA
92130
Common
05/22/2024
10000
453835.00
MICHAEL LABARRE
12390 El Camino Real
San Diego
CA
92130
Common
05/21/2024
10000
451635.00
07/24/2024
03/09/2023
/s/ Michael James LaBarre