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        <com:stateOrCountry>MA</com:stateOrCountry>
        <com:zipCode>02210</com:zipCode>
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      <issuerContactPhone>(877) 442-5362</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Dmytruk Mark E.</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
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          <com:city>Smithfield</com:city>
          <com:stateOrCountry>RI</com:stateOrCountry>
          <com:zipCode>02917</com:zipCode>
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      <approxSaleDate>07/03/2023</approxSaleDate>
      <securitiesExchangeName>NYSE</securitiesExchangeName>
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          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>02210</com:zipCode>
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      <securitiesClassTitle>Class A</securitiesClassTitle>
      <saleDate>04/10/2023</saleDate>
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      <saleDate>05/02/2023</saleDate>
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          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>02210</com:zipCode>
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      </sellerDetails>
      <securitiesClassTitle>Class A</securitiesClassTitle>
      <saleDate>05/22/2023</saleDate>
      <amountOfSecuritiesSold>250000</amountOfSecuritiesSold>
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    <noticeSignature>
      <noticeDate>07/03/2023</noticeDate>
      <signature>/s/ Gary Redman, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Mark Dmytruk</signature>
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144
0001873507
XXXXXXXX
LIVE
0001830214
Ginkgo Bioworks Holdings, Inc.
001-40097
27 DRYDOCK AVENUE
8TH FLOOR
BOSTON
MA
02210
(877) 442-5362
Dmytruk Mark E.
Officer
Class A
Fidelity Brokerage Services LLC
900 Salem Street
Smithfield
RI
02917
40637
73211.64
1585286502
07/03/2023
NYSE
Class A
06/30/2023
Restricted Stock Vesting
Issuer
N
40637
06/30/2023
Compensation
N
Mark Dmytruk
27 Drydock Avenue
8th Floor
Boston
MA
02210
Class A
04/03/2023
38787
49209.07
Mark Dmytruk
27 Drydock Avenue
8th Floor
Boston
MA
02210
Class A
04/10/2023
740
986.64
Mark Dmytruk
27 Drydock Avenue
8th Floor
Boston
MA
02210
Class A
05/02/2023
38802
44517.54
Mark Dmytruk
27 Drydock Avenue
8th Floor
Boston
MA
02210
Class A
05/22/2023
250000
375000.00
Mark Dmytruk
27 Drydock Avenue
8th Floor
Boston
MA
02210
Class A
06/02/2023
40511
63391.61
07/03/2023
/s/ Gary Redman, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Mark Dmytruk