<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001688366</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0001666134</issuerCik>
      <issuerName>BLACKLINE, INC.</issuerName>
      <secFileNumber>001-37924</secFileNumber>
      <issuerAddress>
        <com:street1>21300 VICTORY BOULEVARD</com:street1>
        <com:street2>12TH FLOOR</com:street2>
        <com:city>WOODLAND HILLS</com:city>
        <com:stateOrCountry>CA</com:stateOrCountry>
        <com:zipCode>91367</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>818-223-9008</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Partin Mark</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Officer</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Fidelity Brokerage Services LLC</name>
        <address>
          <com:street1>900 Salem Street</com:street1>
          <com:city>Smithfield</com:city>
          <com:stateOrCountry>RI</com:stateOrCountry>
          <com:zipCode>02917</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>10000</noOfUnitsSold>
      <aggregateMarketValue>665400.00</aggregateMarketValue>
      <noOfUnitsOutstanding>60047142</noOfUnitsOutstanding>
      <approxSaleDate>04/03/2023</approxSaleDate>
      <securitiesExchangeName>NASDAQ</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <acquiredDate>04/03/2023</acquiredDate>
      <natureOfAcquisitionTransaction>Options Granted 03/30/2015</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>10000</amountOfSecuritiesAcquired>
      <paymentDate>04/03/2023</paymentDate>
      <natureOfPayment>Cash</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Mark Partin</name>
        <address>
          <com:street1>21300 Victory Boulevard</com:street1>
          <com:street2>12th Floor</com:street2>
          <com:city>Woodland Hills</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>91367</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <saleDate>02/21/2023</saleDate>
      <amountOfSecuritiesSold>15000</amountOfSecuritiesSold>
      <grossProceeds>1062963.50</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Mark Partin</name>
        <address>
          <com:street1>21300 Victory Boulevard</com:street1>
          <com:street2>12th Floor</com:street2>
          <com:city>Woodland Hills</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>91367</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <saleDate>03/01/2023</saleDate>
      <amountOfSecuritiesSold>10000</amountOfSecuritiesSold>
      <grossProceeds>691557.50</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Mark Partin</name>
        <address>
          <com:street1>21300 Victory Boulevard</com:street1>
          <com:street2>12th Floor</com:street2>
          <com:city>Woodland Hills</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>91367</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <saleDate>03/02/2023</saleDate>
      <amountOfSecuritiesSold>5000</amountOfSecuritiesSold>
      <grossProceeds>350000.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <noticeSignature>
      <noticeDate>04/03/2023</noticeDate>
      <planAdoptionDates>
        <planAdoptionDate>12/09/2022</planAdoptionDate>
      </planAdoptionDates>
      <signature>/s/ Carli McPherson, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Mike Partin</signature>
    </noticeSignature>
  </formData>
</edgarSubmission>
[{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 4904}]
144
0001688366
XXXXXXXX
LIVE
0001666134
BLACKLINE, INC.
001-37924
21300 VICTORY BOULEVARD
12TH FLOOR
WOODLAND HILLS
CA
91367
818-223-9008
Partin Mark
Officer
Common
Fidelity Brokerage Services LLC
900 Salem Street
Smithfield
RI
02917
10000
665400.00
60047142
04/03/2023
NASDAQ
Common
04/03/2023
Options Granted 03/30/2015
Issuer
N
10000
04/03/2023
Cash
N
Mark Partin
21300 Victory Boulevard
12th Floor
Woodland Hills
CA
91367
Common
02/21/2023
15000
1062963.50
Mark Partin
21300 Victory Boulevard
12th Floor
Woodland Hills
CA
91367
Common
03/01/2023
10000
691557.50
Mark Partin
21300 Victory Boulevard
12th Floor
Woodland Hills
CA
91367
Common
03/02/2023
5000
350000.00
04/03/2023
12/09/2022
/s/ Carli McPherson, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Mike Partin