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        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001927856</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001478320</issuerCik>
            <issuerName>ADAPTIVE BIOTECHNOLOGIES CORPORATION</issuerName>
            <secFileNumber>001-38957</secFileNumber>
            <issuerAddress>
                <ns2:street1>1165 Eastlake Avenue East</ns2:street1>
                <ns2:city>Seattle</ns2:city>
                <ns2:stateOrCountry>WA</ns2:stateOrCountry>
                <ns2:zipCode>98109</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>(206) 659-0067</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>TYCHO PETERSON</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>E*TRADE FINANCIAL CORPORATION</name>
                <address>
                    <ns2:street1>3 EDISON DRIVE</ns2:street1>
                    <ns2:city>ALPHARETTA</ns2:city>
                    <ns2:stateOrCountry>GA</ns2:stateOrCountry>
                    <ns2:zipCode>30005</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>70000</noOfUnitsSold>
            <aggregateMarketValue>597367.60</aggregateMarketValue>
            <noOfUnitsOutstanding>144311000</noOfUnitsOutstanding>
            <approxSaleDate>06/15/2023</approxSaleDate>
            <securitiesExchangeName>NASD</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <acquiredDate>06/15/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Stock Option Exercise</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>14328</amountOfSecuritiesAcquired>
            <paymentDate>06/15/2023</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <acquiredDate>06/01/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>55672</amountOfSecuritiesAcquired>
            <paymentDate>06/01/2023</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>TYCHO PETERSON</name>
                <address>
                    <ns2:street1>1165 Eastlake Avenue East</ns2:street1>
                    <ns2:city>Seattle</ns2:city>
                    <ns2:stateOrCountry>WA</ns2:stateOrCountry>
                    <ns2:zipCode>98109</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>common</securitiesClassTitle>
            <saleDate>06/02/2023</saleDate>
            <amountOfSecuritiesSold>38000</amountOfSecuritiesSold>
            <grossProceeds>272057.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>06/15/2023</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>03/10/2023</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Tycho Wyeth Peterson</signature>
        </noticeSignature>
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144
0001927856
XXXXXXXX
LIVE
0001478320
ADAPTIVE BIOTECHNOLOGIES CORPORATION
001-38957
1165 Eastlake Avenue East
Seattle
WA
98109
(206) 659-0067
TYCHO PETERSON
Officer
Common
E*TRADE FINANCIAL CORPORATION
3 EDISON DRIVE
ALPHARETTA
GA
30005
70000
597367.60
144311000
06/15/2023
NASD
COMMON
06/15/2023
Stock Option Exercise
ISSUER
N
14328
06/15/2023
Cash
COMMON
06/01/2023
Restricted Stock
ISSUER
N
55672
06/01/2023
Not Applicable
N
TYCHO PETERSON
1165 Eastlake Avenue East
Seattle
WA
98109
common
06/02/2023
38000
272057.00
06/15/2023
03/10/2023
/s/ Tycho Wyeth Peterson