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                    <ccc>XXXXXXXX</ccc>
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            <liveTestFlag>LIVE</liveTestFlag>



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            <issuerCik>0000882095</issuerCik>
            <issuerName>GILEAD SCIENCES, INC.</issuerName>
            <secFileNumber>000-19731</secFileNumber>
            <issuerAddress>
                <ns2:street1>333 Lakeside Drive</ns2:street1>
                <ns2:city>Foster City</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>94404</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>(650) 574-3000</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>JOHANNA MERCIER</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>3000</noOfUnitsSold>
            <aggregateMarketValue>333090.00</aggregateMarketValue>
            <noOfUnitsOutstanding>1243929121</noOfUnitsOutstanding>
            <approxSaleDate>07/15/2025</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>12/10/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>877</amountOfSecuritiesAcquired>
            <paymentDate>12/10/2023</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>07/24/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>649</amountOfSecuritiesAcquired>
            <paymentDate>07/24/2023</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>09/10/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>1474</amountOfSecuritiesAcquired>
            <paymentDate>09/10/2023</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JOHANNA MERCIER</name>
                <address>
                    <ns2:street1>333 Lakeside Drive</ns2:street1>
                    <ns2:city>Foster City</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94404</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>06/16/2025</saleDate>
            <amountOfSecuritiesSold>3000</amountOfSecuritiesSold>
            <grossProceeds>330510.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JOHANNA MERCIER</name>
                <address>
                    <ns2:street1>333 Lakeside Drive</ns2:street1>
                    <ns2:city>Foster City</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94404</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>05/22/2025</saleDate>
            <amountOfSecuritiesSold>12500</amountOfSecuritiesSold>
            <grossProceeds>1343961.25</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JOHANNA MERCIER</name>
                <address>
                    <ns2:street1>333 Lakeside Drive</ns2:street1>
                    <ns2:city>Foster City</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94404</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>05/22/2025</saleDate>
            <amountOfSecuritiesSold>12500</amountOfSecuritiesSold>
            <grossProceeds>1344037.50</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JOHANNA MERCIER</name>
                <address>
                    <ns2:street1>333 Lakeside Drive</ns2:street1>
                    <ns2:city>Foster City</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94404</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>05/22/2025</saleDate>
            <amountOfSecuritiesSold>860</amountOfSecuritiesSold>
            <grossProceeds>92468.23</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JOHANNA MERCIER</name>
                <address>
                    <ns2:street1>333 Lakeside Drive</ns2:street1>
                    <ns2:city>Foster City</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94404</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>05/22/2025</saleDate>
            <amountOfSecuritiesSold>1458</amountOfSecuritiesSold>
            <grossProceeds>156765.91</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JOHANNA MERCIER</name>
                <address>
                    <ns2:street1>333 Lakeside Drive</ns2:street1>
                    <ns2:city>Foster City</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94404</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>05/22/2025</saleDate>
            <amountOfSecuritiesSold>682</amountOfSecuritiesSold>
            <grossProceeds>73329.46</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>07/15/2025</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>02/20/2025</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Johanna Mercier</signature>
        </noticeSignature>
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144
0001782135
XXXXXXXX
LIVE
0000882095
GILEAD SCIENCES, INC.
000-19731
333 Lakeside Drive
Foster City
CA
94404
(650) 574-3000
JOHANNA MERCIER
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
3000
333090.00
1243929121
07/15/2025
NASDAQ
Common
12/10/2023
Restricted Stock
Issuer
N
877
12/10/2023
Not Applicable
Common
07/24/2023
Restricted Stock
Issuer
N
649
07/24/2023
Not Applicable
Common
09/10/2023
Restricted Stock
Issuer
N
1474
09/10/2023
Not Applicable
N
JOHANNA MERCIER
333 Lakeside Drive
Foster City
CA
94404
Common
06/16/2025
3000
330510.00
JOHANNA MERCIER
333 Lakeside Drive
Foster City
CA
94404
Common
05/22/2025
12500
1343961.25
JOHANNA MERCIER
333 Lakeside Drive
Foster City
CA
94404
Common
05/22/2025
12500
1344037.50
JOHANNA MERCIER
333 Lakeside Drive
Foster City
CA
94404
Common
05/22/2025
860
92468.23
JOHANNA MERCIER
333 Lakeside Drive
Foster City
CA
94404
Common
05/22/2025
1458
156765.91
JOHANNA MERCIER
333 Lakeside Drive
Foster City
CA
94404
Common
05/22/2025
682
73329.46
07/15/2025
02/20/2025
/s/ Johanna Mercier