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            <secFileNumber>000-22705</secFileNumber>
            <issuerAddress>
                <ns2:street1>6027 Edgewood Bend Court</ns2:street1>
                <ns2:city>San Diego</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>92130</ns2:zipCode>
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            <issuerContactPhone>8586177600</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>JULIE  COOKE</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
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        <securitiesInformation>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
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            </brokerOrMarketmakerDetails>
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            <aggregateMarketValue>93275.28</aggregateMarketValue>
            <noOfUnitsOutstanding>99703527</noOfUnitsOutstanding>
            <approxSaleDate>02/13/2025</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
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            <acquiredDate>02/13/2025</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>796</amountOfSecuritiesAcquired>
            <paymentDate>02/13/2025</paymentDate>
            <natureOfPayment>N/A</natureOfPayment>
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                <address>
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                    <ns2:city>San Diego</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>92130</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>02/10/2025</saleDate>
            <amountOfSecuritiesSold>700</amountOfSecuritiesSold>
            <grossProceeds>82792.50</grossProceeds>
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                <address>
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                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>92130</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>01/31/2025</saleDate>
            <amountOfSecuritiesSold>916</amountOfSecuritiesSold>
            <grossProceeds>140045.32</grossProceeds>
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                    <ns2:zipCode>92130</ns2:zipCode>
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            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>01/31/2025</saleDate>
            <amountOfSecuritiesSold>824</amountOfSecuritiesSold>
            <grossProceeds>125979.63</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>02/13/2025</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>03/15/2023</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Julie Cooke</signature>
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144
0001776977
XXXXXXXX
LIVE
0000914475
NEUROCRINE BIOSCIENCES, INC.
000-22705
6027 Edgewood Bend Court
San Diego
CA
92130
8586177600
JULIE  COOKE
Officer
COMMON
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
796
93275.28
99703527
02/13/2025
NASDAQ
Common
02/13/2025
Restricted Stock Units
Issuer
N
796
02/13/2025
N/A
N
10b5-1 Sales Plan for JULIE SMITH COOKE
6027 Edgewood Bend Court
San Diego
CA
92130
COMMON
02/10/2025
700
82792.50
10b5-1 Sales Plan for JULIE SMITH COOKE
6027 Edgewood Bend Court
San Diego
CA
92130
COMMON
01/31/2025
916
140045.32
10b5-1 Sales Plan for JULIE SMITH COOKE
6027 Edgewood Bend Court
San Diego
CA
92130
COMMON
01/31/2025
824
125979.63
02/13/2025
03/15/2023
/s/ Julie Cooke