<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001754765</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001459839</issuerCik>
            <issuerName>SI BONE INC</issuerName>
            <secFileNumber>001-38701</secFileNumber>
            <issuerAddress>
                <ns2:street1>471 El Camino Real, Suite 101</ns2:street1>
                <ns2:city>Santa Clara</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>95050</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>4082070700</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Michael Pisetsky</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>38th Fl.</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>11410</noOfUnitsSold>
            <aggregateMarketValue>253530.20</aggregateMarketValue>
            <noOfUnitsOutstanding>34985640</noOfUnitsOutstanding>
            <approxSaleDate>04/21/2023</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>05/01/2021</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>5410</amountOfSecuritiesAcquired>
            <paymentDate>05/01/2021</paymentDate>
            <natureOfPayment>N/A</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>04/21/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Exercise of Stock Options</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>6000</amountOfSecuritiesAcquired>
            <paymentDate>04/21/2023</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales Plan for MICHAEL ANDREW PISETSKY</name>
                <address>
                    <ns2:street1>471 El Camino Real, Suite 101</ns2:street1>
                    <ns2:city>Santa Clara</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>95050</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>02/28/2023</saleDate>
            <amountOfSecuritiesSold>14293</amountOfSecuritiesSold>
            <grossProceeds>288162.59</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>MICHAEL ANDREW PISETSKY</name>
                <address>
                    <ns2:street1>471 El Camino Real, Suite 101</ns2:street1>
                    <ns2:city>Santa Clara</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>95050</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>02/16/2023</saleDate>
            <amountOfSecuritiesSold>3366</amountOfSecuritiesSold>
            <grossProceeds>56481.48</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>04/21/2023</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>12/16/2022</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Michael Pisetsky</signature>
        </noticeSignature>
    </formData>
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144
0001754765
XXXXXXXX
LIVE
0001459839
SI BONE INC
001-38701
471 El Camino Real, Suite 101
Santa Clara
CA
95050
4082070700
Michael Pisetsky
Officer
COMMON
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
38th Fl.
New York
NY
10004
11410
253530.20
34985640
04/21/2023
NASDAQ
Common
05/01/2021
Restricted Stock Units
Issuer
N
5410
05/01/2021
N/A
Common
04/21/2023
Exercise of Stock Options
Issuer
N
6000
04/21/2023
Cash
N
10b5-1 Sales Plan for MICHAEL ANDREW PISETSKY
471 El Camino Real, Suite 101
Santa Clara
CA
95050
Common
02/28/2023
14293
288162.59
MICHAEL ANDREW PISETSKY
471 El Camino Real, Suite 101
Santa Clara
CA
95050
Common
02/16/2023
3366
56481.48
04/21/2023
12/16/2022
/s/ Michael Pisetsky