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            <ns2:issuerName>Thermo Fisher Scientific Inc.</ns2:issuerName>
            <ns2:secFileNumber>001-08002</ns2:secFileNumber>
            <ns2:issuerAddress>
                <com:street1>168 3RD AVE</com:street1>
                <com:city>WALTHAM</com:city>
                <com:stateOrCountry>MA</com:stateOrCountry>
                <com:zipCode>02451</com:zipCode>
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            <ns2:issuerContactPhone>1-781-622-1000</ns2:issuerContactPhone>
            <ns2:nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Jim Manzi</ns2:nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <ns2:relationshipsToIssuer>
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                <ns2:name>Goldman Sachs &amp; Co. LLC</ns2:name>
                <ns2:address>
                    <com:street1>200 West Street</com:street1>
                    <com:city>New York</com:city>
                    <com:stateOrCountry>NY</com:stateOrCountry>
                    <com:zipCode>10282</com:zipCode>
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            <ns2:noOfUnitsSold>500</ns2:noOfUnitsSold>
            <ns2:aggregateMarketValue>269135</ns2:aggregateMarketValue>
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            <ns2:approxSaleDate>07/21/2023</ns2:approxSaleDate>
            <ns2:securitiesExchangeName>NYSE</ns2:securitiesExchangeName>
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            <ns2:acquiredDate>03/03/2010</ns2:acquiredDate>
            <ns2:natureOfAcquisitionTransaction>Acquired upon option exercise</ns2:natureOfAcquisitionTransaction>
            <ns2:nameOfPersonfromWhomAcquired>Issuer</ns2:nameOfPersonfromWhomAcquired>
            <ns2:isGiftTransaction>N</ns2:isGiftTransaction>
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            <ns2:paymentDate>03/03/2010</ns2:paymentDate>
            <ns2:natureOfPayment>Option exercise</ns2:natureOfPayment>
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        <ns2:nothingToReportFlagOnSecuritiesSoldInPast3Months>N</ns2:nothingToReportFlagOnSecuritiesSoldInPast3Months>
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                <ns2:address>
                    <com:street1>168 3RD AVE</com:street1>
                    <com:city>WALTHAM</com:city>
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                    <com:zipCode>02451</com:zipCode>
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            <ns2:securitiesClassTitle>Common</ns2:securitiesClassTitle>
            <ns2:saleDate>05/25/2023</ns2:saleDate>
            <ns2:amountOfSecuritiesSold>438</ns2:amountOfSecuritiesSold>
            <ns2:grossProceeds>226833.63</ns2:grossProceeds>
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        <ns2:noticeSignature>
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            <ns2:planAdoptionDates/>
            <ns2:signature>Goldman Sachs &amp; Co. LLC on behalf of Jim Manzi</ns2:signature>
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144
0001216076
XXXXXXXX
LIVE
0000097745
Thermo Fisher Scientific Inc.
001-08002
168 3RD AVE
WALTHAM
MA
02451
1-781-622-1000
Jim Manzi
Director
Common
Goldman Sachs & Co. LLC
200 West Street
New York
NY
10282
500
269135
385721286
07/21/2023
NYSE
Common
03/03/2010
Acquired upon option exercise
Issuer
N
500
03/03/2010
Option exercise
N
Jim Manzi
168 3RD AVE
WALTHAM
MA
02451
Common
05/25/2023
438
226833.63
07/21/2023
Goldman Sachs & Co. LLC on behalf of Jim Manzi