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            <filer>
                <filerCredentials>
                    <cik>0001859284</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
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            <liveTestFlag>LIVE</liveTestFlag>



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        <issuerInfo>
            <issuerCik>0001454789</issuerCik>
            <issuerName>ASTRIA THERAPEUTICS, INC.</issuerName>
            <secFileNumber>001-37467</secFileNumber>
            <issuerAddress>
                <ns2:street1>75 State Street Suite 1400</ns2:street1>
                <ns2:city>Boston</ns2:city>
                <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                <ns2:zipCode>02109</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>(617) 349-1971</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>CHRIS MORABITO</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>10000</noOfUnitsSold>
            <aggregateMarketValue>135939.00</aggregateMarketValue>
            <noOfUnitsOutstanding>54903061</noOfUnitsOutstanding>
            <approxSaleDate>04/01/2024</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>04/01/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Stock Option Exercise</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>10000</amountOfSecuritiesAcquired>
            <paymentDate>04/01/2024</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>CHRISTOPHER MORABITO</name>
                <address>
                    <ns2:street1>75 State Street Suite 1400</ns2:street1>
                    <ns2:city>Boston</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02109</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>01/29/2024</saleDate>
            <amountOfSecuritiesSold>9200</amountOfSecuritiesSold>
            <grossProceeds>102552.40</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>CHRISTOPHER MORABITO</name>
                <address>
                    <ns2:street1>75 State Street Suite 1400</ns2:street1>
                    <ns2:city>Boston</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02109</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>01/26/2024</saleDate>
            <amountOfSecuritiesSold>800</amountOfSecuritiesSold>
            <grossProceeds>8812.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>04/01/2024</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>03/31/2023</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Christopher John Morabito</signature>
        </noticeSignature>
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144
0001859284
XXXXXXXX
LIVE
0001454789
ASTRIA THERAPEUTICS, INC.
001-37467
75 State Street Suite 1400
Boston
MA
02109
(617) 349-1971
CHRIS MORABITO
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
10000
135939.00
54903061
04/01/2024
NASDAQ
Common
04/01/2024
Stock Option Exercise
Issuer
N
10000
04/01/2024
Cash
N
CHRISTOPHER MORABITO
75 State Street Suite 1400
Boston
MA
02109
Common
01/29/2024
9200
102552.40
CHRISTOPHER MORABITO
75 State Street Suite 1400
Boston
MA
02109
Common
01/26/2024
800
8812.00
04/01/2024
03/31/2023
/s/ Christopher John Morabito