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    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001540065</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0000784199</issuerCik>
            <issuerName>ARTIVION, INC.</issuerName>
            <secFileNumber>001-13165</secFileNumber>
            <issuerAddress>
                <ns2:street1>1655 ROBERTS BLVD NW</ns2:street1>
                <ns2:city>KENNESAW</ns2:city>
                <ns2:stateOrCountry>GA</ns2:stateOrCountry>
                <ns2:zipCode>30144</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>(770) 419-3355</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>JEAN F HOLLOWAY</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>8748</noOfUnitsSold>
            <aggregateMarketValue>253692.00</aggregateMarketValue>
            <noOfUnitsOutstanding>42702785</noOfUnitsOutstanding>
            <approxSaleDate>05/27/2025</approxSaleDate>
            <securitiesExchangeName>NYSE</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>02/19/2018</acquiredDate>
            <natureOfAcquisitionTransaction>Performance Shares</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>1694</amountOfSecuritiesAcquired>
            <paymentDate>02/19/2018</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/01/2019</acquiredDate>
            <natureOfAcquisitionTransaction>Performance Shares</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>3501</amountOfSecuritiesAcquired>
            <paymentDate>03/01/2019</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>02/21/2020</acquiredDate>
            <natureOfAcquisitionTransaction>Performance Shares</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>1184</amountOfSecuritiesAcquired>
            <paymentDate>02/21/2020</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/05/2018</acquiredDate>
            <natureOfAcquisitionTransaction>Performance Shares</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>2369</amountOfSecuritiesAcquired>
            <paymentDate>03/05/2018</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JEAN F HOLLOWAY</name>
                <address>
                    <ns2:street1>1655 ROBERTS BLVD NW</ns2:street1>
                    <ns2:city>KENNESAW</ns2:city>
                    <ns2:stateOrCountry>GA</ns2:stateOrCountry>
                    <ns2:zipCode>30144</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>05/21/2025</saleDate>
            <amountOfSecuritiesSold>9926</amountOfSecuritiesSold>
            <grossProceeds>287854.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JEAN F HOLLOWAY</name>
                <address>
                    <ns2:street1>1655 ROBERTS BLVD NW</ns2:street1>
                    <ns2:city>KENNESAW</ns2:city>
                    <ns2:stateOrCountry>GA</ns2:stateOrCountry>
                    <ns2:zipCode>30144</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>03/11/2025</saleDate>
            <amountOfSecuritiesSold>18020</amountOfSecuritiesSold>
            <grossProceeds>425509.86</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JEAN F HOLLOWAY</name>
                <address>
                    <ns2:street1>1655 ROBERTS BLVD NW</ns2:street1>
                    <ns2:city>KENNESAW</ns2:city>
                    <ns2:stateOrCountry>GA</ns2:stateOrCountry>
                    <ns2:zipCode>30144</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>03/06/2025</saleDate>
            <amountOfSecuritiesSold>2124</amountOfSecuritiesSold>
            <grossProceeds>52685.29</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JEAN F HOLLOWAY</name>
                <address>
                    <ns2:street1>1655 ROBERTS BLVD NW</ns2:street1>
                    <ns2:city>KENNESAW</ns2:city>
                    <ns2:stateOrCountry>GA</ns2:stateOrCountry>
                    <ns2:zipCode>30144</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>03/05/2025</saleDate>
            <amountOfSecuritiesSold>472</amountOfSecuritiesSold>
            <grossProceeds>11708.57</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>05/27/2025</noticeDate>
            <planAdoptionDates/>
            <signature>/s/ Jean Frames Holloway</signature>
        </noticeSignature>
    </formData>
</edgarSubmission>
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144
0001540065
XXXXXXXX
LIVE
0000784199
ARTIVION, INC.
001-13165
1655 ROBERTS BLVD NW
KENNESAW
GA
30144
(770) 419-3355
JEAN F HOLLOWAY
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
8748
253692.00
42702785
05/27/2025
NYSE
Common
02/19/2018
Performance Shares
ISSUER
N
1694
02/19/2018
Not Applicable
Common
03/01/2019
Performance Shares
ISSUER
N
3501
03/01/2019
Not Applicable
Common
02/21/2020
Performance Shares
ISSUER
N
1184
02/21/2020
Not Applicable
Common
03/05/2018
Performance Shares
ISSUER
N
2369
03/05/2018
Not Applicable
N
JEAN F HOLLOWAY
1655 ROBERTS BLVD NW
KENNESAW
GA
30144
Common
05/21/2025
9926
287854.00
JEAN F HOLLOWAY
1655 ROBERTS BLVD NW
KENNESAW
GA
30144
Common
03/11/2025
18020
425509.86
JEAN F HOLLOWAY
1655 ROBERTS BLVD NW
KENNESAW
GA
30144
Common
03/06/2025
2124
52685.29
JEAN F HOLLOWAY
1655 ROBERTS BLVD NW
KENNESAW
GA
30144
Common
03/05/2025
472
11708.57
05/27/2025
/s/ Jean Frames Holloway