<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001228622</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001517413</issuerCik>
            <issuerName>FASTLY, INC.</issuerName>
            <secFileNumber>001-38897</secFileNumber>
            <issuerAddress>
                <ns2:street1>475 Brannan Street, Suite 300</ns2:street1>
                <ns2:city>San Francisco</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>94107</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>8444327859</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>RONALD KISLING LIVING TRUST </nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>12000</noOfUnitsSold>
            <aggregateMarketValue>88440.00</aggregateMarketValue>
            <noOfUnitsOutstanding>136600000</noOfUnitsOutstanding>
            <approxSaleDate>07/01/2024</approxSaleDate>
            <securitiesExchangeName>NYSE</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>04/15/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>12000</amountOfSecuritiesAcquired>
            <paymentDate>04/15/2024</paymentDate>
            <natureOfPayment>N/A</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>RONALD KISLING </name>
                <address>
                    <ns2:street1>475 Brannan Street, Suite 300</ns2:street1>
                    <ns2:city>San Francisco</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94107</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>05/29/2024</saleDate>
            <amountOfSecuritiesSold>1186</amountOfSecuritiesSold>
            <grossProceeds>10436.80</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>RONALD KISLING </name>
                <address>
                    <ns2:street1>475 Brannan Street, Suite 300</ns2:street1>
                    <ns2:city>San Francisco</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94107</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>05/23/2024</saleDate>
            <amountOfSecuritiesSold>2904</amountOfSecuritiesSold>
            <grossProceeds>25555.20</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>RONALD KISLING </name>
                <address>
                    <ns2:street1>475 Brannan Street, Suite 300</ns2:street1>
                    <ns2:city>San Francisco</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94107</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>05/16/2024</saleDate>
            <amountOfSecuritiesSold>22989</amountOfSecuritiesSold>
            <grossProceeds>196555.95</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>RONALD KISLING </name>
                <address>
                    <ns2:street1>475 Brannan Street, Suite 300</ns2:street1>
                    <ns2:city>San Francisco</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94107</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>04/16/2024</saleDate>
            <amountOfSecuritiesSold>7411</amountOfSecuritiesSold>
            <grossProceeds>96861.77</grossProceeds>
        </securitiesSoldInPast3Months>
        <remarks>The securities to be sold were acquired upon the vesting of restricted stock units during the period of 4/15/2024 through 5/15/2024
</remarks>
        <noticeSignature>
            <noticeDate>07/01/2024</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>11/20/2023</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Ronald Kisling</signature>
        </noticeSignature>
    </formData>
</edgarSubmission>
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144
0001228622
XXXXXXXX
LIVE
0001517413
FASTLY, INC.
001-38897
475 Brannan Street, Suite 300
San Francisco
CA
94107
8444327859
RONALD KISLING LIVING TRUST
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
12000
88440.00
136600000
07/01/2024
NYSE
Common
04/15/2024
Restricted Stock Units
Issuer
N
12000
04/15/2024
N/A
N
RONALD KISLING
475 Brannan Street, Suite 300
San Francisco
CA
94107
Common
05/29/2024
1186
10436.80
RONALD KISLING
475 Brannan Street, Suite 300
San Francisco
CA
94107
Common
05/23/2024
2904
25555.20
RONALD KISLING
475 Brannan Street, Suite 300
San Francisco
CA
94107
Common
05/16/2024
22989
196555.95
RONALD KISLING
475 Brannan Street, Suite 300
San Francisco
CA
94107
Common
04/16/2024
7411
96861.77
The securities to be sold were acquired upon the vesting of restricted stock units during the period of 4/15/2024 through 5/15/2024
07/01/2024
11/20/2023
/s/ Ronald Kisling