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            <filer>
                <filerCredentials>
                    <cik>0001646382</cik>
                    <ccc>XXXXXXXX</ccc>
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            <liveTestFlag>LIVE</liveTestFlag>



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        <issuerInfo>
            <issuerCik>0001604821</issuerCik>
            <issuerName>NATERA INC</issuerName>
            <secFileNumber>001-37478</secFileNumber>
            <issuerAddress>
                <ns2:street1>13011 MCCALLEN PASS</ns2:street1>
                <ns2:street2>Building A Suite 100</ns2:street2>
                <ns2:city>AUSTIN</ns2:city>
                <ns2:stateOrCountry>TX</ns2:stateOrCountry>
                <ns2:zipCode>78753</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>650-980-9190</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>RMDM TRUST U/A DTD 07/31/2020</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Director</relationshipToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>185000</noOfUnitsSold>
            <aggregateMarketValue>19695100.00</aggregateMarketValue>
            <noOfUnitsOutstanding>122802694</noOfUnitsOutstanding>
            <approxSaleDate>05/20/2024</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>05/12/2022</acquiredDate>
            <natureOfAcquisitionTransaction>Open Market Purchase</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>125000</amountOfSecuritiesAcquired>
            <paymentDate>05/12/2022</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/09/2022</acquiredDate>
            <natureOfAcquisitionTransaction>Previously Exercised Stock Options</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>60000</amountOfSecuritiesAcquired>
            <paymentDate>03/09/2022</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales for PREMIER TRUST TTEERMDM TRUST U/A DTD 07/31/2020</name>
                <address>
                    <ns2:street1>13011 MCCALLEN PASS</ns2:street1>
                    <ns2:street2>Building A Suite 100</ns2:street2>
                    <ns2:city>AUSTIN</ns2:city>
                    <ns2:stateOrCountry>TX</ns2:stateOrCountry>
                    <ns2:zipCode>78753</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>03/05/2024</saleDate>
            <amountOfSecuritiesSold>190000</amountOfSecuritiesSold>
            <grossProceeds>16605069.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>05/20/2024</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>11/24/2023</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Matthew Cooper, Premier Trust TTEE on behalf of RMDM Trust U/A DTD 7/31/2020</signature>
        </noticeSignature>
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144
0001646382
XXXXXXXX
LIVE
0001604821
NATERA INC
001-37478
13011 MCCALLEN PASS
Building A Suite 100
AUSTIN
TX
78753
650-980-9190
RMDM TRUST U/A DTD 07/31/2020
Director
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
185000
19695100.00
122802694
05/20/2024
NASDAQ
Common
05/12/2022
Open Market Purchase
Issuer
N
125000
05/12/2022
Cash
Common
03/09/2022
Previously Exercised Stock Options
Issuer
N
60000
03/09/2022
Cash
N
10b5-1 Sales for PREMIER TRUST TTEERMDM TRUST U/A DTD 07/31/2020
13011 MCCALLEN PASS
Building A Suite 100
AUSTIN
TX
78753
Common
03/05/2024
190000
16605069.00
05/20/2024
11/24/2023
/s/ Matthew Cooper, Premier Trust TTEE on behalf of RMDM Trust U/A DTD 7/31/2020