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    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001231589</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001082554</issuerCik>
            <issuerName>UNITED THERAPEUTICS CORPORATION</issuerName>
            <secFileNumber>000-26301</secFileNumber>
            <issuerAddress>
                <ns2:street1>1000 SPRING STREET</ns2:street1>
                <ns2:city>SILVER SPRING</ns2:city>
                <ns2:stateOrCountry>MD</ns2:stateOrCountry>
                <ns2:zipCode>20910</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>(301) 608-9292</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>PAUL MAHON</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>11000</noOfUnitsSold>
            <aggregateMarketValue>3121542.60</aggregateMarketValue>
            <noOfUnitsOutstanding>44912177</noOfUnitsOutstanding>
            <approxSaleDate>04/17/2025</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>04/17/2025</acquiredDate>
            <natureOfAcquisitionTransaction>Stock Options Exercise</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>11000</amountOfSecuritiesAcquired>
            <paymentDate>04/17/2025</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>PAUL MAHON</name>
                <address>
                    <ns2:street1>1000 SPRING STREET</ns2:street1>
                    <ns2:city>SILVER SPRING</ns2:city>
                    <ns2:stateOrCountry>MD</ns2:stateOrCountry>
                    <ns2:zipCode>20910</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>04/03/2025</saleDate>
            <amountOfSecuritiesSold>11000</amountOfSecuritiesSold>
            <grossProceeds>3367983.30</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>04/17/2025</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>12/24/2024</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Paul A. Mahon</signature>
        </noticeSignature>
    </formData>
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144
0001231589
XXXXXXXX
LIVE
0001082554
UNITED THERAPEUTICS CORPORATION
000-26301
1000 SPRING STREET
SILVER SPRING
MD
20910
(301) 608-9292
PAUL MAHON
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
11000
3121542.60
44912177
04/17/2025
NASDAQ
Common
04/17/2025
Stock Options Exercise
Issuer
N
11000
04/17/2025
Cash
N
PAUL MAHON
1000 SPRING STREET
SILVER SPRING
MD
20910
Common
04/03/2025
11000
3367983.30
04/17/2025
12/24/2024
/s/ Paul A. Mahon