<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001558880</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0000002488</issuerCik>
            <issuerName>ADVANCED MICRO DEVICES, INC.</issuerName>
            <secFileNumber>001-07882</secFileNumber>
            <issuerAddress>
                <ns2:street1>2485 Augustine Drive</ns2:street1>
                <ns2:city>Santa Clara</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>95054</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>(408) 749-4000</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>DEVINDER KUMAR</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>38th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>16423</noOfUnitsSold>
            <aggregateMarketValue>1817040.72</aggregateMarketValue>
            <noOfUnitsOutstanding>1615671380</noOfUnitsOutstanding>
            <approxSaleDate>09/06/2023</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <acquiredDate>08/09/2021</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>9989</amountOfSecuritiesAcquired>
            <paymentDate>08/09/2021</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <acquiredDate>08/09/2022</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>6434</amountOfSecuritiesAcquired>
            <paymentDate>08/09/2022</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>DEVINDER KUMAR</name>
                <address>
                    <ns2:street1>2485 Augustine Drive</ns2:street1>
                    <ns2:city>Santa Clara</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>95054</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>08/17/2023</saleDate>
            <amountOfSecuritiesSold>39368</amountOfSecuritiesSold>
            <grossProceeds>4188251.29</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>DEVINDER KUMAR</name>
                <address>
                    <ns2:street1>2485 Augustine Drive</ns2:street1>
                    <ns2:city>Santa Clara</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>95054</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>08/09/2023</saleDate>
            <amountOfSecuritiesSold>15446</amountOfSecuritiesSold>
            <grossProceeds>1744934.62</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>09/06/2023</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>12/09/2022</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Devinder Kumar</signature>
        </noticeSignature>
    </formData>
</edgarSubmission>
[{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 5307}]
144
0001558880
XXXXXXXX
LIVE
0000002488
ADVANCED MICRO DEVICES, INC.
001-07882
2485 Augustine Drive
Santa Clara
CA
95054
(408) 749-4000
DEVINDER KUMAR
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
38th Floor
New York
NY
10004
16423
1817040.72
1615671380
09/06/2023
NASDAQ
COMMON
08/09/2021
Restricted Stock
ISSUER
N
9989
08/09/2021
Not Applicable
COMMON
08/09/2022
Restricted Stock
ISSUER
N
6434
08/09/2022
Not Applicable
N
DEVINDER KUMAR
2485 Augustine Drive
Santa Clara
CA
95054
Common
08/17/2023
39368
4188251.29
DEVINDER KUMAR
2485 Augustine Drive
Santa Clara
CA
95054
Common
08/09/2023
15446
1744934.62
09/06/2023
12/09/2022
/s/ Devinder Kumar