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            <relationshipsToIssuer>
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                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
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            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
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            <isGiftTransaction>N</isGiftTransaction>
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            <paymentDate>01/27/2025</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
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                    <ns2:zipCode>94080</ns2:zipCode>
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            <grossProceeds>264117.83</grossProceeds>
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            <securitiesClassTitle>Common</securitiesClassTitle>
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            <grossProceeds>251274.22</grossProceeds>
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        <securitiesSoldInPast3Months>
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                    <ns2:street1>601 Gateway Boulevard, Suite 350</ns2:street1>
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                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94080</ns2:zipCode>
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            <securitiesClassTitle>Common</securitiesClassTitle>
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                    <ns2:zipCode>94080</ns2:zipCode>
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            <grossProceeds>146855.79</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>01/27/2025</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>05/24/2024</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Catriona Yale</signature>
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144
0001779308
XXXXXXXX
LIVE
0001744659
AKERO THERAPEUTICS INC
001-38944
601 Gateway Boulevard, Suite 350
South San Francisco
CA
94080
6504876488
CATRIONA YALE
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
53591
1403012.38
69799148
01/27/2025
NASDAQ
Common
01/27/2025
Exercise of Stock Options
Issuer
N
53591
01/27/2025
Cash
N
10b5-1 Sales for CATRIONA YALE
601 Gateway Boulevard, Suite 350
South San Francisco
CA
94080
Common
12/16/2024
9074
264117.83
CATRIONA YALE
601 Gateway Boulevard, Suite 350
South San Francisco
CA
94080
Common
12/10/2024
2810
86519.90
10b5-1 Sales for CATRIONA YALE
601 Gateway Boulevard, Suite 350
South San Francisco
CA
94080
Common
11/15/2024
9061
251274.22
10b5-1 Sales for CATRIONA YALE
601 Gateway Boulevard, Suite 350
South San Francisco
CA
94080
Common
11/06/2024
10000
351892.00
10b5-1 Sales for CATRIONA YALE
601 Gateway Boulevard, Suite 350
South San Francisco
CA
94080
Common
11/01/2024
15485
505106.76
10b5-1 Sales for CATRIONA YALE
601 Gateway Boulevard, Suite 350
South San Francisco
CA
94080
Common
10/30/2024
4515
146855.79
01/27/2025
05/24/2024
/s/ Catriona Yale