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    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001490925</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>


    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0001039065</issuerCik>
      <issuerName>OSI SYSTEMS INC</issuerName>
      <secFileNumber>000-23125</secFileNumber>
      <issuerAddress>
        <com:street1>12525 CHADRON AVE</com:street1>
        <com:city>HAWTHORNE</com:city>
        <com:stateOrCountry>CA</com:stateOrCountry>
        <com:zipCode>90250</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>3109780516</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Ballhaus William Francis JR</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Director</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>COMMON</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>FIDELITY BROKERAGE SERVICES LLC</name>
        <address>
          <com:street1>245 SUMMER STREET</com:street1>
          <com:city>BOSTON</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>02110</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>1025</noOfUnitsSold>
      <aggregateMarketValue>129785.50</aggregateMarketValue>
      <noOfUnitsOutstanding>16727882</noOfUnitsOutstanding>
      <approxSaleDate>06/14/2023</approxSaleDate>
      <securitiesExchangeName>NASDAQ</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>COMMON</securitiesClassTitle>
      <acquiredDate>08/05/2019</acquiredDate>
      <natureOfAcquisitionTransaction>STOCK AWARD</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>1025</amountOfSecuritiesAcquired>
      <paymentDate>08/05/2019</paymentDate>
      <natureOfPayment>COMPENSATION</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <remarks>Share sold from Ballhaus Trust</remarks>
    <noticeSignature>
      <noticeDate>06/14/2023</noticeDate>
      <signature>/s/ Carmen Zamores as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Ballhaus William Francis JR</signature>
    </noticeSignature>
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144
0001490925
XXXXXXXX
LIVE
0001039065
OSI SYSTEMS INC
000-23125
12525 CHADRON AVE
HAWTHORNE
CA
90250
3109780516
Ballhaus William Francis JR
Director
COMMON
FIDELITY BROKERAGE SERVICES LLC
245 SUMMER STREET
BOSTON
MA
02110
1025
129785.50
16727882
06/14/2023
NASDAQ
COMMON
08/05/2019
STOCK AWARD
ISSUER
N
1025
08/05/2019
COMPENSATION
Y
Share sold from Ballhaus Trust
06/14/2023
/s/ Carmen Zamores as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Ballhaus William Francis JR