<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001196661</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001099800</issuerCik>
            <issuerName>EDWARDS LIFESCIENCES CORPORATION</issuerName>
            <secFileNumber>001-15525</secFileNumber>
            <issuerAddress>
                <ns2:street1>ONE EDWARDS WAY</ns2:street1>
                <ns2:city>IRVINE</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>92614</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>949-250-6815</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>BOBO JR FAMILY TRUST</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
                <relationshipToIssuer>Director</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>38th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>5635</noOfUnitsSold>
            <aggregateMarketValue>499401.88</aggregateMarketValue>
            <noOfUnitsOutstanding>606218215</noOfUnitsOutstanding>
            <approxSaleDate>05/05/2023</approxSaleDate>
            <securitiesExchangeName>NYSE</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>05/11/2020</acquiredDate>
            <natureOfAcquisitionTransaction>Exercise of Options on under an Issuer Reg Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>2295</amountOfSecuritiesAcquired>
            <paymentDate>05/11/2020</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>05/08/2022</acquiredDate>
            <natureOfAcquisitionTransaction>Exercise of Options on under an Issuer Reg Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>3340</amountOfSecuritiesAcquired>
            <paymentDate>05/08/2022</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>05/05/2023</noticeDate>
            <planAdoptionDates/>
            <signature>/s/ Donald E Bobo Jr, Trustee </signature>
        </noticeSignature>
    </formData>
</edgarSubmission>
[{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 3932}]
144
0001196661
XXXXXXXX
LIVE
0001099800
EDWARDS LIFESCIENCES CORPORATION
001-15525
ONE EDWARDS WAY
IRVINE
CA
92614
949-250-6815
BOBO JR FAMILY TRUST
Officer
Director
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
38th Floor
New York
NY
10004
5635
499401.88
606218215
05/05/2023
NYSE
Common
05/11/2020
Exercise of Options on under an Issuer Reg Plan
Issuer
N
2295
05/11/2020
Cash
Common
05/08/2022
Exercise of Options on under an Issuer Reg Plan
Issuer
N
3340
05/08/2022
Cash
Y
05/05/2023
/s/ Donald E Bobo Jr, Trustee