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    <issuerInfo>
      <issuerCik>0001376339</issuerCik>
      <issuerName>MIMEDX GROUP, INC.</issuerName>
      <secFileNumber>001-35887</secFileNumber>
      <issuerAddress>
        <com:street1>1775 W OAK COMMONS COURT, NE</com:street1>
        <com:city>MARIETTA</com:city>
        <com:stateOrCountry>GA</com:stateOrCountry>
        <com:zipCode>30062</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>(770) 651-9100</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Phelan William Lawrence</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Officer</relationshipToIssuer>
      </relationshipsToIssuer>
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    <securitiesInformation>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>FIDELITY BROKERAGE SERVICES LLC</name>
        <address>
          <com:street1>245 SUMMER STREET</com:street1>
          <com:city>BOSTON</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>02110</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>5200</noOfUnitsSold>
      <aggregateMarketValue>20618.00</aggregateMarketValue>
      <noOfUnitsOutstanding>114083096</noOfUnitsOutstanding>
      <approxSaleDate>05/02/2023</approxSaleDate>
      <securitiesExchangeName>NASDAQ</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>COMMON</securitiesClassTitle>
      <acquiredDate>10/02/2020</acquiredDate>
      <natureOfAcquisitionTransaction>STOCK AWARD</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>5200</amountOfSecuritiesAcquired>
      <paymentDate>10/02/2020</paymentDate>
      <natureOfPayment>COMPENSATION</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>WILLIAM PHELAN</name>
        <address>
          <com:street1>1775 WEST OAK COMMONS COURT NE</com:street1>
          <com:city>MARIAETTA</com:city>
          <com:stateOrCountry>GA</com:stateOrCountry>
          <com:zipCode>300062</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>MIDEX GROUP INC</securitiesClassTitle>
      <saleDate>03/07/2023</saleDate>
      <amountOfSecuritiesSold>3396</amountOfSecuritiesSold>
      <grossProceeds>14414.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>WILLIAM PHELAN</name>
        <address>
          <com:street1>1775 WEST OAK COMMONS COURT NE</com:street1>
          <com:city>MARIAETTA</com:city>
          <com:stateOrCountry>GA</com:stateOrCountry>
          <com:zipCode>300062</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>MIMEDX GROUP INC</securitiesClassTitle>
      <saleDate>04/11/2023</saleDate>
      <amountOfSecuritiesSold>1632</amountOfSecuritiesSold>
      <grossProceeds>5401.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>WILLIAM PHELAN</name>
        <address>
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          <com:stateOrCountry>GA</com:stateOrCountry>
          <com:zipCode>300062</com:zipCode>
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      <securitiesClassTitle>MIMEDX GROUP INC</securitiesClassTitle>
      <saleDate>04/25/2023</saleDate>
      <amountOfSecuritiesSold>1628</amountOfSecuritiesSold>
      <grossProceeds>6095.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <noticeSignature>
      <noticeDate>05/02/2023</noticeDate>
      <signature>/s/ Carmen Zamores as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Phelan William Lawrence</signature>
    </noticeSignature>
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144
0001811814
XXXXXXXX
LIVE
0001376339
MIMEDX GROUP, INC.
001-35887
1775 W OAK COMMONS COURT, NE
MARIETTA
GA
30062
(770) 651-9100
Phelan William Lawrence
Officer
Common
FIDELITY BROKERAGE SERVICES LLC
245 SUMMER STREET
BOSTON
MA
02110
5200
20618.00
114083096
05/02/2023
NASDAQ
COMMON
10/02/2020
STOCK AWARD
ISSUER
N
5200
10/02/2020
COMPENSATION
N
WILLIAM PHELAN
1775 WEST OAK COMMONS COURT NE
MARIAETTA
GA
300062
MIDEX GROUP INC
03/07/2023
3396
14414.00
WILLIAM PHELAN
1775 WEST OAK COMMONS COURT NE
MARIAETTA
GA
300062
MIMEDX GROUP INC
04/11/2023
1632
5401.00
WILLIAM PHELAN
1775 WEST OAK COMMONS COURT NE
MARIAETTA
GA
300062
MIMEDX GROUP INC
04/25/2023
1628
6095.00
05/02/2023
/s/ Carmen Zamores as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Phelan William Lawrence