<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001636178</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001082554</issuerCik>
            <issuerName>United Therapeutics Corporation</issuerName>
            <secFileNumber>000-26301</secFileNumber>
            <issuerAddress>
                <ns2:street1>1000 SPRING ST</ns2:street1>
                <ns2:city>SILVER SPRING</ns2:city>
                <ns2:stateOrCountry>MD</ns2:stateOrCountry>
                <ns2:zipCode>20910</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>3016089292</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>JAMES EDGEMOND</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>111500</noOfUnitsSold>
            <aggregateMarketValue>35551775.00</aggregateMarketValue>
            <noOfUnitsOutstanding>45106623</noOfUnitsOutstanding>
            <approxSaleDate>06/02/2025</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>06/02/2025</acquiredDate>
            <natureOfAcquisitionTransaction>Exercise of Stock Options</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>111500</amountOfSecuritiesAcquired>
            <paymentDate>06/02/2025</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <remarks>The securities to be sold were and will be received upon the exercise of stock options over the next three months. The dates of acquisition and payment were and will be the dates of exercise/sale.
</remarks>
        <noticeSignature>
            <noticeDate>06/02/2025</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>11/05/2024</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ James Edgemond</signature>
        </noticeSignature>
    </formData>
</edgarSubmission>
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144
0001636178
XXXXXXXX
LIVE
0001082554
United Therapeutics Corporation
000-26301
1000 SPRING ST
SILVER SPRING
MD
20910
3016089292
JAMES EDGEMOND
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
111500
35551775.00
45106623
06/02/2025
NASDAQ
Common
06/02/2025
Exercise of Stock Options
Issuer
N
111500
06/02/2025
Cash
Y
The securities to be sold were and will be received upon the exercise of stock options over the next three months. The dates of acquisition and payment were and will be the dates of exercise/sale.
06/02/2025
11/05/2024
/s/ James Edgemond