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                <ns2:city>San Diego</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>92121</ns2:zipCode>
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            <issuerContactPhone>8584017900</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>KATHLEEN GALLAGHER</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
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                    <ns2:street2>8th Floor</ns2:street2>
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                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
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            <aggregateMarketValue>580391.25</aggregateMarketValue>
            <noOfUnitsOutstanding>119309317</noOfUnitsOutstanding>
            <approxSaleDate>02/03/2025</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
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            <natureOfAcquisitionTransaction>Exercise of Stock Options</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
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            <paymentDate>02/03/2025</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
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                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>92121</ns2:zipCode>
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            <grossProceeds>169775.71</grossProceeds>
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                    <ns2:zipCode>92121</ns2:zipCode>
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            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>01/21/2025</saleDate>
            <amountOfSecuritiesSold>2487</amountOfSecuritiesSold>
            <grossProceeds>71112.33</grossProceeds>
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            <saleDate>01/21/2025</saleDate>
            <amountOfSecuritiesSold>1295</amountOfSecuritiesSold>
            <grossProceeds>37024.05</grossProceeds>
        </securitiesSoldInPast3Months>
        <remarks>The securities to be sold were and will be received upon the exercise of stock options over the next three months. The dates of acquisition and payment were and will be the dates of exercise/sale.&#13;
</remarks>
        <noticeSignature>
            <noticeDate>02/03/2025</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>06/12/2024</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Kathleen Gallagher</signature>
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144
0002048409
XXXXXXXX
LIVE
0001599901
Avidity Biosciences, Inc.
001-39321
10578 Science Center Drive, Suite 125
San Diego
CA
92121
8584017900
KATHLEEN GALLAGHER
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
17625
580391.25
119309317
02/03/2025
NASDAQ
Common
02/03/2025
Exercise of Stock Options
Issuer
N
17625
02/03/2025
Cash
N
10b5-1 Sales for KATHLEEN GALLAGHER
10578 Science Center Drive, Suite 125
San Diego
CA
92121
Common
01/22/2025
5629
169775.71
KATHLEEN GALLAGHER
10578 Science Center Drive, Suite 125
San Diego
CA
92121
Common
01/21/2025
2487
71112.33
10b5-1 Sales for KATHLEEN GALLAGHER
10578 Science Center Drive, Suite 125
San Diego
CA
92121
Common
01/21/2025
1295
37024.05
The securities to be sold were and will be received upon the exercise of stock options over the next three months. The dates of acquisition and payment were and will be the dates of exercise/sale.
02/03/2025
06/12/2024
/s/ Kathleen Gallagher