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                    <ccc>XXXXXXXX</ccc>
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            <liveTestFlag>LIVE</liveTestFlag>



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        <issuerInfo>
            <issuerCik>0001815442</issuerCik>
            <issuerName>KYMERA THERAPEUTICS, INC.</issuerName>
            <secFileNumber>001-39460</secFileNumber>
            <issuerAddress>
                <ns2:street1>200 Arsenal Yards Blvd., Suite 230</ns2:street1>
                <ns2:city>Watertown</ns2:city>
                <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                <ns2:zipCode>02472</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>8572855300</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>JARED GOLLOB</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>23145</noOfUnitsSold>
            <aggregateMarketValue>1041525.00</aggregateMarketValue>
            <noOfUnitsOutstanding>61358262</noOfUnitsOutstanding>
            <approxSaleDate>07/16/2024</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>07/16/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Exercise of Stock Options</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>23145</amountOfSecuritiesAcquired>
            <paymentDate>07/16/2024</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales for JARED AUGUST GOLLOB</name>
                <address>
                    <ns2:street1>200 Arsenal Yards Blvd., Suite 230</ns2:street1>
                    <ns2:city>Watertown</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02472</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>07/15/2024</saleDate>
            <amountOfSecuritiesSold>16455</amountOfSecuritiesSold>
            <grossProceeds>742925.15</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>07/16/2024</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>03/22/2023</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Jared Gollob</signature>
        </noticeSignature>
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144
0001821198
XXXXXXXX
LIVE
0001815442
KYMERA THERAPEUTICS, INC.
001-39460
200 Arsenal Yards Blvd., Suite 230
Watertown
MA
02472
8572855300
JARED GOLLOB
Officer
COMMON
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
23145
1041525.00
61358262
07/16/2024
NASDAQ
Common
07/16/2024
Exercise of Stock Options
Issuer
N
23145
07/16/2024
Cash
N
10b5-1 Sales for JARED AUGUST GOLLOB
200 Arsenal Yards Blvd., Suite 230
Watertown
MA
02472
COMMON
07/15/2024
16455
742925.15
07/16/2024
03/22/2023
/s/ Jared Gollob