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    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001646382</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001604821</issuerCik>
            <issuerName>NATERA INC</issuerName>
            <secFileNumber>001-37478</secFileNumber>
            <issuerAddress>
                <ns2:street1>13011 MCCALLEN PASS Building A Suite 100</ns2:street1>
                <ns2:city>AUSTIN</ns2:city>
                <ns2:stateOrCountry>TX</ns2:stateOrCountry>
                <ns2:zipCode>78753</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>6509809190</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>MATTHEW RABINOWITZ</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Director</relationshipToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>160000</noOfUnitsSold>
            <aggregateMarketValue>26632000.00</aggregateMarketValue>
            <noOfUnitsOutstanding>132020816</noOfUnitsOutstanding>
            <approxSaleDate>12/13/2024</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>12/05/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Previously Exercised Options</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>68496</amountOfSecuritiesAcquired>
            <paymentDate>12/05/2024</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>05/12/2022</acquiredDate>
            <natureOfAcquisitionTransaction>Open Market Purchase</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>91504</amountOfSecuritiesAcquired>
            <paymentDate>05/12/2022</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>MATTHEW RABINOWITZ</name>
                <address>
                    <ns2:street1>13011 MCCALLEN PASS Building A Suite 100</ns2:street1>
                    <ns2:city>AUSTIN</ns2:city>
                    <ns2:stateOrCountry>TX</ns2:stateOrCountry>
                    <ns2:zipCode>78753</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>11/26/2024</saleDate>
            <amountOfSecuritiesSold>2000</amountOfSecuritiesSold>
            <grossProceeds>328340.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>MATTHEW RABINOWITZ</name>
                <address>
                    <ns2:street1>13011 MCCALLEN PASS Building A Suite 100</ns2:street1>
                    <ns2:city>AUSTIN</ns2:city>
                    <ns2:stateOrCountry>TX</ns2:stateOrCountry>
                    <ns2:zipCode>78753</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>11/25/2024</saleDate>
            <amountOfSecuritiesSold>2000</amountOfSecuritiesSold>
            <grossProceeds>337020.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>12/13/2024</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>09/13/2024</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Matthew Rabinowitz</signature>
        </noticeSignature>
    </formData>
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144
0001646382
XXXXXXXX
LIVE
0001604821
NATERA INC
001-37478
13011 MCCALLEN PASS Building A Suite 100
AUSTIN
TX
78753
6509809190
MATTHEW RABINOWITZ
Director
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
160000
26632000.00
132020816
12/13/2024
NASDAQ
Common
12/05/2024
Previously Exercised Options
Issuer
N
68496
12/05/2024
Cash
Common
05/12/2022
Open Market Purchase
Issuer
N
91504
05/12/2022
Cash
N
MATTHEW RABINOWITZ
13011 MCCALLEN PASS Building A Suite 100
AUSTIN
TX
78753
Common
11/26/2024
2000
328340.00
MATTHEW RABINOWITZ
13011 MCCALLEN PASS Building A Suite 100
AUSTIN
TX
78753
Common
11/25/2024
2000
337020.00
12/13/2024
09/13/2024
/s/ Matthew Rabinowitz