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      <issuerName>DiaMedica Therapeutics Inc.</issuerName>
      <secFileNumber>001-36291</secFileNumber>
      <issuerAddress>
        <com:street1>301 CARLSON PARKWAY</com:street1>
        <com:street2>SUITE 210</com:street2>
        <com:city>MINNEAPOLIS</com:city>
        <com:stateOrCountry>MN</com:stateOrCountry>
        <com:zipCode>55305</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>(763) 496-5454</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Daves Julie VanOrsdel</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Officer</relationshipToIssuer>
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        <name>Ameriprise Financial</name>
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          <com:street1>2865 Ameriprise Financial Center</com:street1>
          <com:city>Minneapolis</com:city>
          <com:stateOrCountry>MN</com:stateOrCountry>
          <com:zipCode>55474</com:zipCode>
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      <noOfUnitsSold>39700</noOfUnitsSold>
      <aggregateMarketValue>109462.60</aggregateMarketValue>
      <noOfUnitsOutstanding>37963916</noOfUnitsOutstanding>
      <approxSaleDate>07/01/2024</approxSaleDate>
      <securitiesExchangeName>NASDAQ</securitiesExchangeName>
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      <acquiredDate>07/01/2024</acquiredDate>
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      <nameOfPersonfromWhomAcquired>DiaMedica Therapeutics</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
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      <paymentDate>07/01/2024</paymentDate>
      <natureOfPayment>Non Qualified Stock Option Exercise</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <remarks>Sell to cover employee stock option exercise.</remarks>
    <noticeSignature>
      <noticeDate>07/02/2024</noticeDate>
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144
0001945603
XXXXXXXX
LIVE
0001401040
DiaMedica Therapeutics Inc.
001-36291
301 CARLSON PARKWAY
SUITE 210
MINNEAPOLIS
MN
55305
(763) 496-5454
Daves Julie VanOrsdel
Officer
Common
Ameriprise Financial
2865 Ameriprise Financial Center
Minneapolis
MN
55474
39700
109462.60
37963916
07/01/2024
NASDAQ
Common
07/01/2024
Employee Stock Option Exercise
DiaMedica Therapeutics
N
52500
07/01/2024
Non Qualified Stock Option Exercise
Y
Sell to cover employee stock option exercise.
07/02/2024
Julie Daves