<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001559655</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0000858877</issuerCik>
            <issuerName>Cisco Systems, Inc.</issuerName>
            <secFileNumber>001-39940</secFileNumber>
            <issuerAddress>
                <ns2:street1>170 West Tasman Drive</ns2:street1>
                <ns2:city>San Jose</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>95134</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>4085264000</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>CHARLES ROBBINS</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Director</relationshipToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>38th Fl.</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>49212</noOfUnitsSold>
            <aggregateMarketValue>2470934.52</aggregateMarketValue>
            <noOfUnitsOutstanding>4075058155</noOfUnitsOutstanding>
            <approxSaleDate>06/06/2023</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>05/10/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Dividend Equivalent Shares</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>910</amountOfSecuritiesAcquired>
            <paymentDate>05/10/2023</paymentDate>
            <natureOfPayment>N/A</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>09/11/2015</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>45932</amountOfSecuritiesAcquired>
            <paymentDate>09/11/2015</paymentDate>
            <natureOfPayment>N/A</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>06/29/2018</acquiredDate>
            <natureOfAcquisitionTransaction>Employee Stock Purchase Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>2370</amountOfSecuritiesAcquired>
            <paymentDate>06/29/2018</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <remarks>The securities to be sold were acquired upon the vesting of restricted stock units during the period of
9/11/2015 through 5/10/2023.

The securities to be sold were acquired upon the purchase of Employee Stock Purchase Plan during the period of
6/29/2018 through 6/30/2021.</remarks>
        <noticeSignature>
            <noticeDate>06/06/2023</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>03/07/2023</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Charles Robbins</signature>
        </noticeSignature>
    </formData>
</edgarSubmission>
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144
0001559655
XXXXXXXX
LIVE
0000858877
Cisco Systems, Inc.
001-39940
170 West Tasman Drive
San Jose
CA
95134
4085264000
CHARLES ROBBINS
Director
Officer
COMMON
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
38th Fl.
New York
NY
10004
49212
2470934.52
4075058155
06/06/2023
NASDAQ
Common
05/10/2023
Dividend Equivalent Shares
Issuer
N
910
05/10/2023
N/A
Common
09/11/2015
Restricted Stock Units
Issuer
N
45932
09/11/2015
N/A
Common
06/29/2018
Employee Stock Purchase Plan
Issuer
N
2370
06/29/2018
Cash
Y
The securities to be sold were acquired upon the vesting of restricted stock units during the period of
9/11/2015 through 5/10/2023.

The securities to be sold were acquired upon the purchase of Employee Stock Purchase Plan during the period of
6/29/2018 through 6/30/2021.
06/06/2023
03/07/2023
/s/ Charles Robbins