<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001796825</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001261333</issuerCik>
            <issuerName>DOCUSIGN, INC.</issuerName>
            <secFileNumber>001-38465</secFileNumber>
            <issuerAddress>
                <ns2:street1>221 Main Street, Suite 1550</ns2:street1>
                <ns2:city>San Francisco</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>94105</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>(415) 489-4940</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>BLAKE J GRAYSON</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>9552</noOfUnitsSold>
            <aggregateMarketValue>657232.61</aggregateMarketValue>
            <noOfUnitsOutstanding>202972713</noOfUnitsOutstanding>
            <approxSaleDate>10/15/2024</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <acquiredDate>12/10/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>983</amountOfSecuritiesAcquired>
            <paymentDate>12/10/2023</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <acquiredDate>09/10/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>7017</amountOfSecuritiesAcquired>
            <paymentDate>09/10/2023</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <acquiredDate>08/10/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>1552</amountOfSecuritiesAcquired>
            <paymentDate>08/10/2024</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>BLAKE J GRAYSON</name>
                <address>
                    <ns2:street1>221 Main Street, Suite 1550</ns2:street1>
                    <ns2:city>San Francisco</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94105</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>09/18/2024</saleDate>
            <amountOfSecuritiesSold>14036</amountOfSecuritiesSold>
            <grossProceeds>778519.37</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>10/15/2024</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>06/28/2024</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Blake Jeffrey Grayson</signature>
        </noticeSignature>
    </formData>
</edgarSubmission>
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144
0001796825
XXXXXXXX
LIVE
0001261333
DOCUSIGN, INC.
001-38465
221 Main Street, Suite 1550
San Francisco
CA
94105
(415) 489-4940
BLAKE J GRAYSON
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
9552
657232.61
202972713
10/15/2024
NASDAQ
COMMON
12/10/2023
Restricted Stock
ISSUER
N
983
12/10/2023
Not Applicable
COMMON
09/10/2023
Restricted Stock
ISSUER
N
7017
09/10/2023
Not Applicable
COMMON
08/10/2024
Restricted Stock
ISSUER
N
1552
08/10/2024
Not Applicable
N
BLAKE J GRAYSON
221 Main Street, Suite 1550
San Francisco
CA
94105
Common
09/18/2024
14036
778519.37
10/15/2024
06/28/2024
/s/ Blake Jeffrey Grayson