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                <filerCredentials>
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                    <ccc>XXXXXXXX</ccc>
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            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



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        <issuerInfo>
            <issuerCik>0001651308</issuerCik>
            <issuerName>BeOne Medicines Ltd.</issuerName>
            <secFileNumber>001-37686</secFileNumber>
            <issuerAddress>
                <ns2:street1>Aeschengraben 27, 21st Floor</ns2:street1>
                <ns2:city>Basel</ns2:city>
                <ns2:stateOrCountry>V8</ns2:stateOrCountry>
                <ns2:zipCode>4051</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>41-616851900</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>XIAODONG WANG</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Director</relationshipToIssuer>
                <relationshipToIssuer>Chair</relationshipToIssuer>
                <relationshipToIssuer> Scientific Advisory Brd</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>ADS</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>2007</noOfUnitsSold>
            <aggregateMarketValue>516822.57</aggregateMarketValue>
            <noOfUnitsOutstanding>56964739</noOfUnitsOutstanding>
            <approxSaleDate>06/24/2025</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>ADS</securitiesClassTitle>
            <acquiredDate>06/15/2025</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>2007</amountOfSecuritiesAcquired>
            <paymentDate>06/15/2025</paymentDate>
            <natureOfPayment>N/A</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales for XIAODONG WANG</name>
                <address>
                    <ns2:street1>Aeschengraben 27, 21st Floor</ns2:street1>
                    <ns2:city>Basel</ns2:city>
                    <ns2:stateOrCountry>V8</ns2:stateOrCountry>
                    <ns2:zipCode>4051</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>ADS</securitiesClassTitle>
            <saleDate>06/10/2025</saleDate>
            <amountOfSecuritiesSold>41760</amountOfSecuritiesSold>
            <grossProceeds>10975317.26</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales for XIAODONG WANG</name>
                <address>
                    <ns2:street1>Aeschengraben 27, 21st Floor</ns2:street1>
                    <ns2:city>Basel</ns2:city>
                    <ns2:stateOrCountry>V8</ns2:stateOrCountry>
                    <ns2:zipCode>4051</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>ADS</securitiesClassTitle>
            <saleDate>05/13/2025</saleDate>
            <amountOfSecuritiesSold>41760</amountOfSecuritiesSold>
            <grossProceeds>9333272.30</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales for XIAODONG WANG</name>
                <address>
                    <ns2:street1>Aeschengraben 27, 21st Floor</ns2:street1>
                    <ns2:city>Basel</ns2:city>
                    <ns2:stateOrCountry>V8</ns2:stateOrCountry>
                    <ns2:zipCode>4051</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>ADS</securitiesClassTitle>
            <saleDate>04/14/2025</saleDate>
            <amountOfSecuritiesSold>41760</amountOfSecuritiesSold>
            <grossProceeds>10133594.35</grossProceeds>
        </securitiesSoldInPast3Months>
        <remarks>The securities to be sold were acquired upon the vesting of restricted stock units on 06/15/2025, 06/16/2025 and 06/22/2025.
</remarks>
        <noticeSignature>
            <noticeDate>06/24/2025</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>08/12/2024</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Xiaodong Wang</signature>
        </noticeSignature>
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144
0001662982
XXXXXXXX
LIVE
0001651308
BeOne Medicines Ltd.
001-37686
Aeschengraben 27, 21st Floor
Basel
V8
4051
41-616851900
XIAODONG WANG
Director
Chair
Scientific Advisory Brd
ADS
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
2007
516822.57
56964739
06/24/2025
NASDAQ
ADS
06/15/2025
Restricted Stock Units
Issuer
N
2007
06/15/2025
N/A
N
10b5-1 Sales for XIAODONG WANG
Aeschengraben 27, 21st Floor
Basel
V8
4051
ADS
06/10/2025
41760
10975317.26
10b5-1 Sales for XIAODONG WANG
Aeschengraben 27, 21st Floor
Basel
V8
4051
ADS
05/13/2025
41760
9333272.30
10b5-1 Sales for XIAODONG WANG
Aeschengraben 27, 21st Floor
Basel
V8
4051
ADS
04/14/2025
41760
10133594.35
The securities to be sold were acquired upon the vesting of restricted stock units on 06/15/2025, 06/16/2025 and 06/22/2025.
06/24/2025
08/12/2024
/s/ Xiaodong Wang