<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001438538</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0001099800</issuerCik>
      <issuerName>Edwards Lifesciences Corp</issuerName>
      <secFileNumber>001-15525</secFileNumber>
      <issuerAddress>
        <com:street1>ONE EDWARDS WAY</com:street1>
        <com:city>IRVINE</com:city>
        <com:stateOrCountry>CA</com:stateOrCountry>
        <com:zipCode>92614</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>9492502500</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Szyman Catherine M.</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Officer</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Charles Schwab &amp; Co., Inc.</name>
        <address>
          <com:street1>3000 Schwab Way</com:street1>
          <com:city>Westlake</com:city>
          <com:stateOrCountry>TX</com:stateOrCountry>
          <com:zipCode>76262</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>85600</noOfUnitsSold>
      <aggregateMarketValue>7613683.00</aggregateMarketValue>
      <noOfUnitsOutstanding>606218215</noOfUnitsOutstanding>
      <approxSaleDate>05/09/2023</approxSaleDate>
      <securitiesExchangeName>NYSE</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <acquiredDate>05/09/2023</acquiredDate>
      <natureOfAcquisitionTransaction>Employee Stock Option Exercise - See Remarks</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>EDWARDS LIFESCIENCES CORPORATION</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>85600</amountOfSecuritiesAcquired>
      <paymentDate>05/09/2023</paymentDate>
      <natureOfPayment>Broker Payment for Cashless Exercise</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <remarks>The shares in this filing are intended to be sold on various dates over the next 3 months.</remarks>
    <noticeSignature>
      <noticeDate>05/09/2023</noticeDate>
      <planAdoptionDates>
        <planAdoptionDate>02/06/2023</planAdoptionDate>
      </planAdoptionDates>
      <signature>CATHERINE M SZYMAN</signature>
    </noticeSignature>
  </formData>
</edgarSubmission>
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144
0001438538
XXXXXXXX
LIVE
0001099800
Edwards Lifesciences Corp
001-15525
ONE EDWARDS WAY
IRVINE
CA
92614
9492502500
Szyman Catherine M.
Officer
Common
Charles Schwab & Co., Inc.
3000 Schwab Way
Westlake
TX
76262
85600
7613683.00
606218215
05/09/2023
NYSE
Common
05/09/2023
Employee Stock Option Exercise - See Remarks
EDWARDS LIFESCIENCES CORPORATION
N
85600
05/09/2023
Broker Payment for Cashless Exercise
Y
The shares in this filing are intended to be sold on various dates over the next 3 months.
05/09/2023
02/06/2023
CATHERINE M SZYMAN