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                <filerCredentials>
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                    <ccc>XXXXXXXX</ccc>
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            <liveTestFlag>LIVE</liveTestFlag>



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        <issuerInfo>
            <issuerCik>0001434647</issuerCik>
            <issuerName>ZEVRA THERAPEUTICS INC</issuerName>
            <secFileNumber>001-36913</secFileNumber>
            <issuerAddress>
                <ns2:street1>1180 Celebration Boulevard, Suite 103</ns2:street1>
                <ns2:city>Celebration</ns2:city>
                <ns2:stateOrCountry>FL</ns2:stateOrCountry>
                <ns2:zipCode>34747</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>3219393416</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Joshua Schafer</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>10500</noOfUnitsSold>
            <aggregateMarketValue>81060.00</aggregateMarketValue>
            <noOfUnitsOutstanding>5337593</noOfUnitsOutstanding>
            <approxSaleDate>02/13/2025</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>01/31/2025</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>10500</amountOfSecuritiesAcquired>
            <paymentDate>01/31/2025</paymentDate>
            <natureOfPayment>N/A</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>02/13/2025</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>10/15/2024</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Joshua Schafer</signature>
        </noticeSignature>
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144
0001945557
XXXXXXXX
LIVE
0001434647
ZEVRA THERAPEUTICS INC
001-36913
1180 Celebration Boulevard, Suite 103
Celebration
FL
34747
3219393416
Joshua Schafer
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
10500
81060.00
5337593
02/13/2025
NASDAQ
Common
01/31/2025
Restricted Stock Units
Issuer
N
10500
01/31/2025
N/A
Y
02/13/2025
10/15/2024
/s/ Joshua Schafer