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            <secFileNumber>001-34822</secFileNumber>
            <issuerAddress>
                <ns2:street1>120 S. Sierra Ave</ns2:street1>
                <ns2:street2>Suite</ns2:street2>
                <ns2:city>Solana Beach</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>92075</ns2:zipCode>
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            <issuerContactPhone>888-287-9109</issuerContactPhone>
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            <relationshipsToIssuer>
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                <relationshipToIssuer>Director</relationshipToIssuer>
            </relationshipsToIssuer>
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            <securitiesClassTitle>Common</securitiesClassTitle>
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                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
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            <noOfUnitsSold>21247</noOfUnitsSold>
            <aggregateMarketValue>282357.76</aggregateMarketValue>
            <noOfUnitsOutstanding>27989194</noOfUnitsOutstanding>
            <approxSaleDate>06/09/2025</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
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            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>21247</amountOfSecuritiesAcquired>
            <paymentDate>03/06/2025</paymentDate>
            <natureOfPayment>Services Rendered</natureOfPayment>
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        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
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                    <ns2:street2>Suite</ns2:street2>
                    <ns2:city>Solana Beach</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>92075</ns2:zipCode>
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            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>03/12/2025</saleDate>
            <amountOfSecuritiesSold>23405</amountOfSecuritiesSold>
            <grossProceeds>558592.38</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>06/09/2025</noticeDate>
            <planAdoptionDates/>
            <signature>/s/ Joseph Michael Burnett, Trustee</signature>
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144
0001721010
XXXXXXXX
LIVE
0001285550
ClearPoint Neuro, Inc.
001-34822
120 S. Sierra Ave
Suite
Solana Beach
CA
92075
888-287-9109
JOSEPH M BURNETT TRUST
Officer
Director
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
21247
282357.76
27989194
06/09/2025
NASDAQ
Common
03/06/2025
Restricted stock vesting under a registered plan
Issuer
N
21247
03/06/2025
Services Rendered
N
Joseph M Burnett
120 S. Sierra Ave
Suite
Solana Beach
CA
92075
Common
03/12/2025
23405
558592.38
06/09/2025
/s/ Joseph Michael Burnett, Trustee