<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001959750</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0000873303</issuerCik>
            <issuerName>SAREPTA THERAPEUTICS INC </issuerName>
            <secFileNumber>001-14895</secFileNumber>
            <issuerAddress>
                <ns2:street1>215 First Street Suite 415</ns2:street1>
                <ns2:city>Cambridge</ns2:city>
                <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                <ns2:zipCode>02142</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>617-274-4000</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>BILAL ARIF</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>7859</noOfUnitsSold>
            <aggregateMarketValue>1263098.48</aggregateMarketValue>
            <noOfUnitsOutstanding>94523766</noOfUnitsOutstanding>
            <approxSaleDate>06/24/2024</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>02/28/2020</acquiredDate>
            <natureOfAcquisitionTransaction>Employee Stock Purchase Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>933</amountOfSecuritiesAcquired>
            <paymentDate>02/28/2020</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/29/2020</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>6926</amountOfSecuritiesAcquired>
            <paymentDate>03/29/2020</paymentDate>
            <natureOfPayment>N/A</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <remarks>The securities to be sold were acquired upon the vesting of restricted stock units during the period of 03/29/2020 through 03/07/2024.

</remarks>
        <noticeSignature>
            <noticeDate>06/24/2024</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>03/11/2024</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Bilal Arif</signature>
        </noticeSignature>
    </formData>
</edgarSubmission>
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144
0001959750
XXXXXXXX
LIVE
0000873303
SAREPTA THERAPEUTICS INC
001-14895
215 First Street Suite 415
Cambridge
MA
02142
617-274-4000
BILAL ARIF
Officer
COMMON
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
7859
1263098.48
94523766
06/24/2024
NASDAQ
Common
02/28/2020
Employee Stock Purchase Plan
Issuer
N
933
02/28/2020
Cash
Common
03/29/2020
Restricted Stock Units
Issuer
N
6926
03/29/2020
N/A
Y
The securities to be sold were acquired upon the vesting of restricted stock units during the period of 03/29/2020 through 03/07/2024.
06/24/2024
03/11/2024
/s/ Bilal Arif