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      <issuerCik>0001314052</issuerCik>
      <issuerName>ANAVEX LIFE SCIENCES CORP.</issuerName>
      <secFileNumber>001-37606</secFileNumber>
      <issuerAddress>
        <com:street1>51 W 52ND STREET,</com:street1>
        <com:street2>7TH FLOOR</com:street2>
        <com:city>NEW YORK</com:city>
        <com:stateOrCountry>NY</com:stateOrCountry>
        <com:zipCode>10019-6163</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>800-689-3939</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>MISSLING CHRISTOPHER U</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Officer</relationshipToIssuer>
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    <securitiesInformation>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Charles Schwab Corp.</name>
        <address>
          <com:street1>3000 Schwab Way</com:street1>
          <com:city>Westlake</com:city>
          <com:stateOrCountry>TX</com:stateOrCountry>
          <com:zipCode>76262</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>268000</noOfUnitsSold>
      <aggregateMarketValue>2144000.00</aggregateMarketValue>
      <noOfUnitsOutstanding>80837723</noOfUnitsOutstanding>
      <approxSaleDate>06/28/2023</approxSaleDate>
      <securitiesExchangeName>Nasdaq</securitiesExchangeName>
    </securitiesInformation>
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      <securitiesClassTitle>Common</securitiesClassTitle>
      <acquiredDate>06/28/2023</acquiredDate>
      <natureOfAcquisitionTransaction>Stock Option Exercise</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>268000</amountOfSecuritiesAcquired>
      <paymentDate>06/28/2023</paymentDate>
      <natureOfPayment>Broker's Check</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <noticeSignature>
      <noticeDate>06/28/2023</noticeDate>
      <signature>Christopher Missling</signature>
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144
0001196573
XXXXXXXX
LIVE
0001314052
ANAVEX LIFE SCIENCES CORP.
001-37606
51 W 52ND STREET,
7TH FLOOR
NEW YORK
NY
10019-6163
800-689-3939
MISSLING CHRISTOPHER U
Officer
Common
Charles Schwab Corp.
3000 Schwab Way
Westlake
TX
76262
268000
2144000.00
80837723
06/28/2023
Nasdaq
Common
06/28/2023
Stock Option Exercise
Issuer
N
268000
06/28/2023
Broker's Check
Y
06/28/2023
Christopher Missling