<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001805306</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>


    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0001360442</issuerCik>
      <issuerName>Cannabis Sativa, Inc.</issuerName>
      <secFileNumber>000-53571</secFileNumber>
      <issuerAddress>
        <com:street1>355 W MESQUITE BLVD</com:street1>
        <com:street2>C70</com:street2>
        <com:city>MESQUITE</com:city>
        <com:stateOrCountry>NV</com:stateOrCountry>
        <com:zipCode>89027</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>323-420-8683</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Tankson Robert N. III</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Director</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Wilson-Davis &amp; Co</name>
        <address>
          <com:street1>236 So. Main Street</com:street1>
          <com:city>Salt Lake City, UT</com:city>
          <com:stateOrCountry>UT</com:stateOrCountry>
          <com:zipCode>84101</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>1018146</noOfUnitsSold>
      <aggregateMarketValue>19039.00</aggregateMarketValue>
      <noOfUnitsOutstanding>101814674</noOfUnitsOutstanding>
      <approxSaleDate>07/19/2024</approxSaleDate>
      <securitiesExchangeName>otcqb</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <acquiredDate>12/31/2023</acquiredDate>
      <natureOfAcquisitionTransaction>Salary Shares Sale of company</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Cannabis Sativa, Inc.</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>5371849</amountOfSecuritiesAcquired>
      <paymentDate>01/01/2024</paymentDate>
      <natureOfPayment>Services</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <noticeSignature>
      <noticeDate>07/16/2024</noticeDate>
      <signature>Robert N. Tankson</signature>
    </noticeSignature>
  </formData>
</edgarSubmission>
[{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 2789}]
144
0001805306
XXXXXXXX
LIVE
0001360442
Cannabis Sativa, Inc.
000-53571
355 W MESQUITE BLVD
C70
MESQUITE
NV
89027
323-420-8683
Tankson Robert N. III
Director
Common
Wilson-Davis & Co
236 So. Main Street
Salt Lake City, UT
UT
84101
1018146
19039.00
101814674
07/19/2024
otcqb
Common
12/31/2023
Salary Shares Sale of company
Cannabis Sativa, Inc.
N
5371849
01/01/2024
Services
Y
07/16/2024
Robert N. Tankson