<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001222012</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001682852</issuerCik>
            <issuerName>Moderna, Inc.</issuerName>
            <secFileNumber>001-38753</secFileNumber>
            <issuerAddress>
                <ns2:street1>325 Binney Street</ns2:street1>
                <ns2:city>Cambridge</ns2:city>
                <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                <ns2:zipCode>02142</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>6177146500</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>NOUBAR B AFEYAN</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Director</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>15000</noOfUnitsSold>
            <aggregateMarketValue>1782600.00</aggregateMarketValue>
            <noOfUnitsOutstanding>383239726</noOfUnitsOutstanding>
            <approxSaleDate>07/31/2024</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>05/01/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Private Placement</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>15000</amountOfSecuritiesAcquired>
            <paymentDate>05/01/2024</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales Plan for NOUBAR B AFEYAN</name>
                <address>
                    <ns2:street1>325 Binney Street</ns2:street1>
                    <ns2:city>Cambridge</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02142</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>07/24/2024</saleDate>
            <amountOfSecuritiesSold>15000</amountOfSecuritiesSold>
            <grossProceeds>1766971.50</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales Plan for NOUBAR B AFEYAN</name>
                <address>
                    <ns2:street1>325 Binney Street</ns2:street1>
                    <ns2:city>Cambridge</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02142</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>07/17/2024</saleDate>
            <amountOfSecuritiesSold>15000</amountOfSecuritiesSold>
            <grossProceeds>1842651.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales Plan for NOUBAR B AFEYAN</name>
                <address>
                    <ns2:street1>325 Binney Street</ns2:street1>
                    <ns2:city>Cambridge</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02142</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>07/10/2024</saleDate>
            <amountOfSecuritiesSold>15000</amountOfSecuritiesSold>
            <grossProceeds>1756177.50</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales Plan for NOUBAR B AFEYAN</name>
                <address>
                    <ns2:street1>325 Binney Street</ns2:street1>
                    <ns2:city>Cambridge</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02142</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>06/26/2024</saleDate>
            <amountOfSecuritiesSold>15000</amountOfSecuritiesSold>
            <grossProceeds>1908294.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales Plan for NOUBAR B AFEYAN</name>
                <address>
                    <ns2:street1>325 Binney Street</ns2:street1>
                    <ns2:city>Cambridge</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02142</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>06/18/2024</saleDate>
            <amountOfSecuritiesSold>15000</amountOfSecuritiesSold>
            <grossProceeds>2003562.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales Plan for NOUBAR B AFEYAN</name>
                <address>
                    <ns2:street1>325 Binney Street</ns2:street1>
                    <ns2:city>Cambridge</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02142</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>06/12/2024</saleDate>
            <amountOfSecuritiesSold>15000</amountOfSecuritiesSold>
            <grossProceeds>2208072.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>Flagship Ventures IV-RX, LP</name>
                <address>
                    <ns2:street1>325 Binney Street</ns2:street1>
                    <ns2:city>Cambridge</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02142</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>06/11/2024</saleDate>
            <amountOfSecuritiesSold>32763</amountOfSecuritiesSold>
            <grossProceeds>4859942.20</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>Flagship Ventures IV, LP</name>
                <address>
                    <ns2:street1>325 Binney Street</ns2:street1>
                    <ns2:city>Cambridge</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02142</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>06/11/2024</saleDate>
            <amountOfSecuritiesSold>170069</amountOfSecuritiesSold>
            <grossProceeds>25227406.20</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales Plan for NOUBAR B AFEYAN</name>
                <address>
                    <ns2:street1>325 Binney Street</ns2:street1>
                    <ns2:city>Cambridge</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02142</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>06/05/2024</saleDate>
            <amountOfSecuritiesSold>15000</amountOfSecuritiesSold>
            <grossProceeds>2268804.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales Plan for NOUBAR B AFEYAN</name>
                <address>
                    <ns2:street1>325 Binney Street</ns2:street1>
                    <ns2:city>Cambridge</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02142</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>05/29/2024</saleDate>
            <amountOfSecuritiesSold>20000</amountOfSecuritiesSold>
            <grossProceeds>2901586.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales Plan for NOUBAR B AFEYAN</name>
                <address>
                    <ns2:street1>325 Binney Street</ns2:street1>
                    <ns2:city>Cambridge</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02142</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>05/22/2024</saleDate>
            <amountOfSecuritiesSold>15000</amountOfSecuritiesSold>
            <grossProceeds>2363556.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales Plan for NOUBAR B AFEYAN</name>
                <address>
                    <ns2:street1>325 Binney Street</ns2:street1>
                    <ns2:city>Cambridge</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02142</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>05/15/2024</saleDate>
            <amountOfSecuritiesSold>15000</amountOfSecuritiesSold>
            <grossProceeds>1909863.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales Plan for NOUBAR B AFEYAN</name>
                <address>
                    <ns2:street1>325 Binney Street</ns2:street1>
                    <ns2:city>Cambridge</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02142</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>05/08/2024</saleDate>
            <amountOfSecuritiesSold>15000</amountOfSecuritiesSold>
            <grossProceeds>1825219.50</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales Plan for NOUBAR B AFEYAN</name>
                <address>
                    <ns2:street1>325 Binney Street</ns2:street1>
                    <ns2:city>Cambridge</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02142</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>05/01/2024</saleDate>
            <amountOfSecuritiesSold>15000</amountOfSecuritiesSold>
            <grossProceeds>1663854.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>07/31/2024</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>11/07/2023</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Noubar B. Afeyan</signature>
        </noticeSignature>
    </formData>
</edgarSubmission>
[{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 13296}]
144
0001222012
XXXXXXXX
LIVE
0001682852
Moderna, Inc.
001-38753
325 Binney Street
Cambridge
MA
02142
6177146500
NOUBAR B AFEYAN
Director
COMMON
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
15000
1782600.00
383239726
07/31/2024
NASDAQ
Common
05/01/2024
Private Placement
Issuer
N
15000
05/01/2024
Cash
N
10b5-1 Sales Plan for NOUBAR B AFEYAN
325 Binney Street
Cambridge
MA
02142
COMMON
07/24/2024
15000
1766971.50
10b5-1 Sales Plan for NOUBAR B AFEYAN
325 Binney Street
Cambridge
MA
02142
COMMON
07/17/2024
15000
1842651.00
10b5-1 Sales Plan for NOUBAR B AFEYAN
325 Binney Street
Cambridge
MA
02142
COMMON
07/10/2024
15000
1756177.50
10b5-1 Sales Plan for NOUBAR B AFEYAN
325 Binney Street
Cambridge
MA
02142
COMMON
06/26/2024
15000
1908294.00
10b5-1 Sales Plan for NOUBAR B AFEYAN
325 Binney Street
Cambridge
MA
02142
COMMON
06/18/2024
15000
2003562.00
10b5-1 Sales Plan for NOUBAR B AFEYAN
325 Binney Street
Cambridge
MA
02142
COMMON
06/12/2024
15000
2208072.00
Flagship Ventures IV-RX, LP
325 Binney Street
Cambridge
MA
02142
Common
06/11/2024
32763
4859942.20
Flagship Ventures IV, LP
325 Binney Street
Cambridge
MA
02142
Common
06/11/2024
170069
25227406.20
10b5-1 Sales Plan for NOUBAR B AFEYAN
325 Binney Street
Cambridge
MA
02142
COMMON
06/05/2024
15000
2268804.00
10b5-1 Sales Plan for NOUBAR B AFEYAN
325 Binney Street
Cambridge
MA
02142
COMMON
05/29/2024
20000
2901586.00
10b5-1 Sales Plan for NOUBAR B AFEYAN
325 Binney Street
Cambridge
MA
02142
COMMON
05/22/2024
15000
2363556.00
10b5-1 Sales Plan for NOUBAR B AFEYAN
325 Binney Street
Cambridge
MA
02142
COMMON
05/15/2024
15000
1909863.00
10b5-1 Sales Plan for NOUBAR B AFEYAN
325 Binney Street
Cambridge
MA
02142
COMMON
05/08/2024
15000
1825219.50
10b5-1 Sales Plan for NOUBAR B AFEYAN
325 Binney Street
Cambridge
MA
02142
COMMON
05/01/2024
15000
1663854.00
07/31/2024
11/07/2023
/s/ Noubar B. Afeyan