<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
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        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001962926</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



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        <issuerInfo>
            <issuerCik>0001888886</issuerCik>
            <issuerName>Structure Therapeutics Inc.</issuerName>
            <secFileNumber>001-41608</secFileNumber>
            <issuerAddress>
                <ns2:street1>601 Gateway Blvd., Suite 900</ns2:street1>
                <ns2:city>South San Francisco</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>94080</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>6504571978</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>XICHEN LIN</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>59000</noOfUnitsSold>
            <aggregateMarketValue>2017800.00</aggregateMarketValue>
            <noOfUnitsOutstanding>139863370</noOfUnitsOutstanding>
            <approxSaleDate>06/03/2024</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>06/03/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Exercise of Stock Options</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>59000</amountOfSecuritiesAcquired>
            <paymentDate>06/03/2024</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <remarks>The securities to be sold were and will be received upon the exercise of stock options over the next three months.&#13;
The date of acquisition and payment was and will be the date of exercise/sale.&#13;
</remarks>
        <noticeSignature>
            <noticeDate>06/03/2024</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>12/28/2023</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Xichen Lin</signature>
        </noticeSignature>
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144
0001962926
XXXXXXXX
LIVE
0001888886
Structure Therapeutics Inc.
001-41608
601 Gateway Blvd., Suite 900
South San Francisco
CA
94080
6504571978
XICHEN LIN
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
59000
2017800.00
139863370
06/03/2024
NASDAQ
Common
06/03/2024
Exercise of Stock Options
Issuer
N
59000
06/03/2024
Cash
Y
The securities to be sold were and will be received upon the exercise of stock options over the next three months.
The date of acquisition and payment was and will be the date of exercise/sale.
06/03/2024
12/28/2023
/s/ Xichen Lin