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      <issuerCik>0001369568</issuerCik>
      <issuerName>CATALYST PHARMACEUTICALS, INC.</issuerName>
      <secFileNumber>001-33057</secFileNumber>
      <issuerAddress>
        <com:street1>355 ALHAMBRA CIRCLE</com:street1>
        <com:street2>SUITE 801</com:street2>
        <com:city>CORAL GABLES</com:city>
        <com:stateOrCountry>FL</com:stateOrCountry>
        <com:zipCode>33134</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>(305) 420-3200</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>MCENANY PATRICK J</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Director</relationshipToIssuer>
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    <securitiesInformation>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Charles Schwab Corporation</name>
        <address>
          <com:street1>3000 Schwab Way</com:street1>
          <com:city>Westlake</com:city>
          <com:stateOrCountry>TX</com:stateOrCountry>
          <com:zipCode>76262</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>200000</noOfUnitsSold>
      <aggregateMarketValue>5176000.00</aggregateMarketValue>
      <noOfUnitsOutstanding>121975152</noOfUnitsOutstanding>
      <approxSaleDate>06/06/2025</approxSaleDate>
      <securitiesExchangeName>NASDAQ</securitiesExchangeName>
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      <securitiesClassTitle>Common</securitiesClassTitle>
      <acquiredDate>03/14/2002</acquiredDate>
      <natureOfAcquisitionTransaction>Private Placement</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>200000</amountOfSecuritiesAcquired>
      <paymentDate>03/14/2002</paymentDate>
      <natureOfPayment>Cash/Check</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <noticeSignature>
      <noticeDate>06/06/2025</noticeDate>
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144
0000929985
XXXXXXXX
LIVE
0001369568
CATALYST PHARMACEUTICALS, INC.
001-33057
355 ALHAMBRA CIRCLE
SUITE 801
CORAL GABLES
FL
33134
(305) 420-3200
MCENANY PATRICK J
Director
Common
Charles Schwab Corporation
3000 Schwab Way
Westlake
TX
76262
200000
5176000.00
121975152
06/06/2025
NASDAQ
Common
03/14/2002
Private Placement
Issuer
N
200000
03/14/2002
Cash/Check
Y
06/06/2025
PATRICK MCENANY