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      <issuerCik>0001819790</issuerCik>
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      <secFileNumber>001-39614</secFileNumber>
      <issuerAddress>
        <com:street1>15440 LAGUNA CANYON ROAD</com:street1>
        <com:city>IRVINE</com:city>
        <com:stateOrCountry>CA</com:stateOrCountry>
        <com:zipCode>92618</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>(949) 409-9820</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Mottiwala Aziz</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Officer</relationshipToIssuer>
      </relationshipsToIssuer>
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    <securitiesInformation>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Fidelity Brokerage Services LLC</name>
        <address>
          <com:street1>900 Salem Street</com:street1>
          <com:city>Smithfield</com:city>
          <com:stateOrCountry>RI</com:stateOrCountry>
          <com:zipCode>02917</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>2143</noOfUnitsSold>
      <aggregateMarketValue>39876.47</aggregateMarketValue>
      <noOfUnitsOutstanding>26803733</noOfUnitsOutstanding>
      <approxSaleDate>06/06/2023</approxSaleDate>
      <securitiesExchangeName>NASDAQ</securitiesExchangeName>
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      <securitiesClassTitle>Common</securitiesClassTitle>
      <acquiredDate>07/27/2020</acquiredDate>
      <natureOfAcquisitionTransaction>Stock Option Exercise</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>2143</amountOfSecuritiesAcquired>
      <paymentDate>07/27/2020</paymentDate>
      <natureOfPayment>Cash</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <noticeSignature>
      <noticeDate>06/06/2023</noticeDate>
      <planAdoptionDates>
        <planAdoptionDate>08/15/2022</planAdoptionDate>
      </planAdoptionDates>
      <signature>/s/Wade Moss, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Aziz A Mottiwala</signature>
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144
0001788542
XXXXXXXX
LIVE
0001819790
Tarsus Pharmaceuticals, Inc.
001-39614
15440 LAGUNA CANYON ROAD
IRVINE
CA
92618
(949) 409-9820
Mottiwala Aziz
Officer
Common
Fidelity Brokerage Services LLC
900 Salem Street
Smithfield
RI
02917
2143
39876.47
26803733
06/06/2023
NASDAQ
Common
07/27/2020
Stock Option Exercise
Issuer
N
2143
07/27/2020
Cash
Y
06/06/2023
08/15/2022
/s/Wade Moss, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Aziz A Mottiwala