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    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001984186</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0001613103</issuerCik>
      <issuerName>Medtronic plc</issuerName>
      <secFileNumber>001-36820</secFileNumber>
      <issuerAddress>
        <com:street1>20 ON HATCH, LOWER HATCH STREET</com:street1>
        <com:city>DUBLIN</com:city>
        <com:stateOrCountry>L2</com:stateOrCountry>
        <com:zipCode>2</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>01135314381700</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Marinaro Michael</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Officer</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Fidelity Brokerage Services, LLC.</name>
        <address>
          <com:street1>900 Salem Street</com:street1>
          <com:city>Smithfield</com:city>
          <com:stateOrCountry>RI</com:stateOrCountry>
          <com:zipCode>02917</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>1352</noOfUnitsSold>
      <aggregateMarketValue>113716.72</aggregateMarketValue>
      <noOfUnitsOutstanding>1330405428</noOfUnitsOutstanding>
      <approxSaleDate>08/04/2023</approxSaleDate>
      <securitiesExchangeName>NYSE</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <acquiredDate>08/03/2023</acquiredDate>
      <natureOfAcquisitionTransaction>Restricted Stock Vesting</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>790</amountOfSecuritiesAcquired>
      <paymentDate>08/03/2023</paymentDate>
      <natureOfPayment>Compensation</natureOfPayment>
    </securitiesToBeSold>
    <securitiesToBeSold>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <acquiredDate>08/03/2023</acquiredDate>
      <natureOfAcquisitionTransaction>Performance Shares</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>562</amountOfSecuritiesAcquired>
      <paymentDate>08/03/2023</paymentDate>
      <natureOfPayment>Compensation</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Michael Marinaro</name>
        <address>
          <com:street1>20 On Hatch, Lower Hatch Street</com:street1>
          <com:city>Dublin 2</com:city>
          <com:stateOrCountry>L2</com:stateOrCountry>
          <com:zipCode>D02</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <saleDate>05/15/2023</saleDate>
      <amountOfSecuritiesSold>619</amountOfSecuritiesSold>
      <grossProceeds>55159.09</grossProceeds>
    </securitiesSoldInPast3Months>
    <noticeSignature>
      <noticeDate>08/04/2023</noticeDate>
      <planAdoptionDates>
        <planAdoptionDate>04/12/2023</planAdoptionDate>
      </planAdoptionDates>
      <signature>/s/ Daniel Tucci, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Michael Marinaro</signature>
    </noticeSignature>
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144
0001984186
XXXXXXXX
LIVE
0001613103
Medtronic plc
001-36820
20 ON HATCH, LOWER HATCH STREET
DUBLIN
L2
2
01135314381700
Marinaro Michael
Officer
Common
Fidelity Brokerage Services, LLC.
900 Salem Street
Smithfield
RI
02917
1352
113716.72
1330405428
08/04/2023
NYSE
Common
08/03/2023
Restricted Stock Vesting
Issuer
N
790
08/03/2023
Compensation
Common
08/03/2023
Performance Shares
Issuer
N
562
08/03/2023
Compensation
N
Michael Marinaro
20 On Hatch, Lower Hatch Street
Dublin 2
L2
D02
Common
05/15/2023
619
55159.09
08/04/2023
04/12/2023
/s/ Daniel Tucci, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Michael Marinaro