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            <filer>
                <filerCredentials>
                    <cik>0001779458</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



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            <issuerCik>0001314102</issuerCik>
            <issuerName>EYEPOINT PHARMACEUTICALS INC</issuerName>
            <secFileNumber>000-51122</secFileNumber>
            <issuerAddress>
                <ns2:street1>480 Pleasant Street</ns2:street1>
                <ns2:city>Watertown</ns2:city>
                <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                <ns2:zipCode>02472</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>617-926-5000</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>DAVID S JONES</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>38th Fl.</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>34442</noOfUnitsSold>
            <aggregateMarketValue>857950.22</aggregateMarketValue>
            <noOfUnitsOutstanding>48838843</noOfUnitsOutstanding>
            <approxSaleDate>01/24/2024</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>01/24/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Exercise of Stock Options</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>34442</amountOfSecuritiesAcquired>
            <paymentDate>01/24/2024</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales for DAVID S JONES</name>
                <address>
                    <ns2:street1>480 Pleasant Street</ns2:street1>
                    <ns2:city>Watertown</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02472</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>01/23/2024</saleDate>
            <amountOfSecuritiesSold>900</amountOfSecuritiesSold>
            <grossProceeds>22500.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales for DAVID S JONES</name>
                <address>
                    <ns2:street1>480 Pleasant Street</ns2:street1>
                    <ns2:city>Watertown</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02472</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>01/22/2024</saleDate>
            <amountOfSecuritiesSold>34166</amountOfSecuritiesSold>
            <grossProceeds>772691.34</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>01/24/2024</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>09/21/2023</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ David S Jones</signature>
        </noticeSignature>
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144
0001779458
XXXXXXXX
LIVE
0001314102
EYEPOINT PHARMACEUTICALS INC
000-51122
480 Pleasant Street
Watertown
MA
02472
617-926-5000
DAVID S JONES
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
38th Fl.
New York
NY
10004
34442
857950.22
48838843
01/24/2024
NASDAQ
Common
01/24/2024
Exercise of Stock Options
Issuer
N
34442
01/24/2024
Cash
N
10b5-1 Sales for DAVID S JONES
480 Pleasant Street
Watertown
MA
02472
Common
01/23/2024
900
22500.00
10b5-1 Sales for DAVID S JONES
480 Pleasant Street
Watertown
MA
02472
Common
01/22/2024
34166
772691.34
01/24/2024
09/21/2023
/s/ David S Jones