<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001797971</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001093557</issuerCik>
            <issuerName>DEXCOM, INC.</issuerName>
            <secFileNumber>000-51222</secFileNumber>
            <issuerAddress>
                <ns2:street1>6340 Sequence Drive</ns2:street1>
                <ns2:city>San Diego</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>92121</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>(858) 200-0200</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>SADIE STERN</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>8688</noOfUnitsSold>
            <aggregateMarketValue>1151396.13</aggregateMarketValue>
            <noOfUnitsOutstanding>385515421</noOfUnitsOutstanding>
            <approxSaleDate>03/12/2024</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <acquiredDate>03/08/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>4324</amountOfSecuritiesAcquired>
            <paymentDate>03/08/2023</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <acquiredDate>11/19/2022</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>4364</amountOfSecuritiesAcquired>
            <paymentDate>11/19/2022</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>SADIE STERN</name>
                <address>
                    <ns2:street1>6340 Sequence Drive</ns2:street1>
                    <ns2:city>San Diego</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>92121</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>01/16/2024</saleDate>
            <amountOfSecuritiesSold>2902</amountOfSecuritiesSold>
            <grossProceeds>358788.19</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>SADIE STERN</name>
                <address>
                    <ns2:street1>6340 Sequence Drive</ns2:street1>
                    <ns2:city>San Diego</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>92121</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>12/18/2023</saleDate>
            <amountOfSecuritiesSold>1675</amountOfSecuritiesSold>
            <grossProceeds>204097.78</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>03/12/2024</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>12/12/2023</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Sadie Stern</signature>
        </noticeSignature>
    </formData>
</edgarSubmission>
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144
0001797971
XXXXXXXX
LIVE
0001093557
DEXCOM, INC.
000-51222
6340 Sequence Drive
San Diego
CA
92121
(858) 200-0200
SADIE STERN
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
8688
1151396.13
385515421
03/12/2024
NASDAQ
COMMON
03/08/2023
Restricted Stock
ISSUER
N
4324
03/08/2023
Not Applicable
COMMON
11/19/2022
Restricted Stock
ISSUER
N
4364
11/19/2022
Not Applicable
N
SADIE STERN
6340 Sequence Drive
San Diego
CA
92121
Common
01/16/2024
2902
358788.19
SADIE STERN
6340 Sequence Drive
San Diego
CA
92121
Common
12/18/2023
1675
204097.78
03/12/2024
12/12/2023
/s/ Sadie Stern