<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001913491</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0001835268</issuerCik>
      <issuerName>Connect Biopharma Holdings Ltd</issuerName>
      <secFileNumber>001-40212</secFileNumber>
      <issuerAddress>
        <com:street1>3580 CARMEL MOUNTAIN ROAD, SUITE 200</com:street1>
        <com:city>SAN DIEGO</com:city>
        <com:stateOrCountry>CA</com:stateOrCountry>
        <com:zipCode>92130</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>858-727-1040</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Wei Zheng</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>10% Stockholder</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Ordinary Shares</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Individual Filer</name>
        <address>
          <com:street1>PO Box 415</com:street1>
          <com:street2>122 15th Street</com:street2>
          <com:city>Del Mar</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>92014</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>39775</noOfUnitsSold>
      <aggregateMarketValue>32217.75</aggregateMarketValue>
      <noOfUnitsOutstanding>55561056</noOfUnitsOutstanding>
      <approxSaleDate>06/11/2025</approxSaleDate>
      <securitiesExchangeName>N/A</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Ordinary Shares</securitiesClassTitle>
      <acquiredDate>03/19/2021</acquiredDate>
      <natureOfAcquisitionTransaction>Compensation-Stock Award</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>39775</amountOfSecuritiesAcquired>
      <paymentDate>03/19/2021</paymentDate>
      <natureOfPayment>No payment - Stock awarded as compensation for services</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <remarks>This is a private transaction in which the seller listed in Section 2(a) above is selling the ordinary shares described above directly to the issuer's current Chief Executive Officer, Barry D. Quart, Pharm.D., at market price.</remarks>
    <noticeSignature>
      <noticeDate>06/11/2025</noticeDate>
      <signature>zheng Wei</signature>
    </noticeSignature>
  </formData>
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144
0001913491
XXXXXXXX
LIVE
0001835268
Connect Biopharma Holdings Ltd
001-40212
3580 CARMEL MOUNTAIN ROAD, SUITE 200
SAN DIEGO
CA
92130
858-727-1040
Wei Zheng
10% Stockholder
Ordinary Shares
Individual Filer
PO Box 415
122 15th Street
Del Mar
CA
92014
39775
32217.75
55561056
06/11/2025
N/A
Ordinary Shares
03/19/2021
Compensation-Stock Award
Issuer
N
39775
03/19/2021
No payment - Stock awarded as compensation for services
Y
This is a private transaction in which the seller listed in Section 2(a) above is selling the ordinary shares described above directly to the issuer's current Chief Executive Officer, Barry D. Quart, Pharm.D., at market price.
06/11/2025
zheng Wei