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        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001321402</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001437402</issuerCik>
            <issuerName>ARDELYX INC</issuerName>
            <secFileNumber>001-36485</secFileNumber>
            <issuerAddress>
                <ns2:street1>400 Fifth Avenue Suite 210</ns2:street1>
                <ns2:city>Waltham</ns2:city>
                <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                <ns2:zipCode>02451</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>5107451700</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>MICHAEL RAAB</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Director</relationshipToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>166666</noOfUnitsSold>
            <aggregateMarketValue>833330.00</aggregateMarketValue>
            <noOfUnitsOutstanding>236854270</noOfUnitsOutstanding>
            <approxSaleDate>01/07/2025</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>01/07/2025</acquiredDate>
            <natureOfAcquisitionTransaction>Exercise of Stock Options</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>83333</amountOfSecuritiesAcquired>
            <paymentDate>01/07/2025</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>09/14/2020</acquiredDate>
            <natureOfAcquisitionTransaction>Performance Stock Units</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>83333</amountOfSecuritiesAcquired>
            <paymentDate>09/14/2020</paymentDate>
            <natureOfPayment>N/A</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>MICHAEL RAAB</name>
                <address>
                    <ns2:street1>400 Fifth Avenue Suite 210</ns2:street1>
                    <ns2:city>Waltham</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02451</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>12/10/2024</saleDate>
            <amountOfSecuritiesSold>25000</amountOfSecuritiesSold>
            <grossProceeds>131620.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>MICHAEL RAAB</name>
                <address>
                    <ns2:street1>400 Fifth Avenue Suite 210</ns2:street1>
                    <ns2:city>Waltham</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02451</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>11/25/2024</saleDate>
            <amountOfSecuritiesSold>25000</amountOfSecuritiesSold>
            <grossProceeds>134482.50</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>MICHAEL RAAB</name>
                <address>
                    <ns2:street1>400 Fifth Avenue Suite 210</ns2:street1>
                    <ns2:city>Waltham</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02451</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>11/20/2024</saleDate>
            <amountOfSecuritiesSold>31980</amountOfSecuritiesSold>
            <grossProceeds>153328.11</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>MICHAEL RAAB</name>
                <address>
                    <ns2:street1>400 Fifth Avenue Suite 210</ns2:street1>
                    <ns2:city>Waltham</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02451</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>11/11/2024</saleDate>
            <amountOfSecuritiesSold>2743</amountOfSecuritiesSold>
            <grossProceeds>13440.70</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>MICHAEL RAAB</name>
                <address>
                    <ns2:street1>400 Fifth Avenue Suite 210</ns2:street1>
                    <ns2:city>Waltham</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02451</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>10/28/2024</saleDate>
            <amountOfSecuritiesSold>25000</amountOfSecuritiesSold>
            <grossProceeds>147740.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>MICHAEL RAAB</name>
                <address>
                    <ns2:street1>400 Fifth Avenue Suite 210</ns2:street1>
                    <ns2:city>Waltham</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02451</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>10/11/2024</saleDate>
            <amountOfSecuritiesSold>7500</amountOfSecuritiesSold>
            <grossProceeds>45075.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <remarks>The securities to be sold were and will be received upon the exercise of stock options over the next three months. The dates of acquisition and payment were and will be the dates of exercise/sale.&#13;
</remarks>
        <noticeSignature>
            <noticeDate>01/07/2025</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>09/04/2024</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Michael Raab</signature>
        </noticeSignature>
    </formData>
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144
0001321402
XXXXXXXX
LIVE
0001437402
ARDELYX INC
001-36485
400 Fifth Avenue Suite 210
Waltham
MA
02451
5107451700
MICHAEL RAAB
Director
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
166666
833330.00
236854270
01/07/2025
NASDAQ
Common
01/07/2025
Exercise of Stock Options
Issuer
N
83333
01/07/2025
Cash
Common
09/14/2020
Performance Stock Units
Issuer
N
83333
09/14/2020
N/A
N
MICHAEL RAAB
400 Fifth Avenue Suite 210
Waltham
MA
02451
Common
12/10/2024
25000
131620.00
MICHAEL RAAB
400 Fifth Avenue Suite 210
Waltham
MA
02451
Common
11/25/2024
25000
134482.50
MICHAEL RAAB
400 Fifth Avenue Suite 210
Waltham
MA
02451
Common
11/20/2024
31980
153328.11
MICHAEL RAAB
400 Fifth Avenue Suite 210
Waltham
MA
02451
Common
11/11/2024
2743
13440.70
MICHAEL RAAB
400 Fifth Avenue Suite 210
Waltham
MA
02451
Common
10/28/2024
25000
147740.00
MICHAEL RAAB
400 Fifth Avenue Suite 210
Waltham
MA
02451
Common
10/11/2024
7500
45075.00
The securities to be sold were and will be received upon the exercise of stock options over the next three months. The dates of acquisition and payment were and will be the dates of exercise/sale.
01/07/2025
09/04/2024
/s/ Michael Raab