<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001502558</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001101239</issuerCik>
            <issuerName>EQUINIX INC,COM.</issuerName>
            <secFileNumber>001-40205</secFileNumber>
            <issuerAddress>
                <ns2:street1>One Lagoon Drive</ns2:street1>
                <ns2:city>Redwood City</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>94065</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>6505986000</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>CHARLES J MEYERS</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>3562</noOfUnitsSold>
            <aggregateMarketValue>3319427.80</aggregateMarketValue>
            <noOfUnitsOutstanding>97332005</noOfUnitsOutstanding>
            <approxSaleDate>02/19/2025</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>02/15/2025</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>3562</amountOfSecuritiesAcquired>
            <paymentDate>02/15/2025</paymentDate>
            <natureOfPayment>N/A</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales for CHARLES J MEYERS </name>
                <address>
                    <ns2:street1>One Lagoon Drive</ns2:street1>
                    <ns2:city>Redwood City</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94065</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>01/17/2025</saleDate>
            <amountOfSecuritiesSold>4241</amountOfSecuritiesSold>
            <grossProceeds>3905916.20</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales for CHARLES J MEYERS </name>
                <address>
                    <ns2:street1>One Lagoon Drive</ns2:street1>
                    <ns2:city>Redwood City</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94065</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>01/16/2025</saleDate>
            <amountOfSecuritiesSold>5788</amountOfSecuritiesSold>
            <grossProceeds>5265987.23</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>02/19/2025</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>06/05/2024</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Charles J Meyers</signature>
        </noticeSignature>
    </formData>
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144
0001502558
XXXXXXXX
LIVE
0001101239
EQUINIX INC,COM.
001-40205
One Lagoon Drive
Redwood City
CA
94065
6505986000
CHARLES J MEYERS
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
3562
3319427.80
97332005
02/19/2025
NASDAQ
Common
02/15/2025
Restricted Stock Units
Issuer
N
3562
02/15/2025
N/A
N
10b5-1 Sales for CHARLES J MEYERS
One Lagoon Drive
Redwood City
CA
94065
Common
01/17/2025
4241
3905916.20
10b5-1 Sales for CHARLES J MEYERS
One Lagoon Drive
Redwood City
CA
94065
Common
01/16/2025
5788
5265987.23
02/19/2025
06/05/2024
/s/ Charles J Meyers