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            <filer>
                <filerCredentials>
                    <cik>0001241357</cik>
                    <ccc>XXXXXXXX</ccc>
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            <liveTestFlag>LIVE</liveTestFlag>



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        <issuerInfo>
            <issuerCik>0001060736</issuerCik>
            <issuerName>SEAGEN INC.</issuerName>
            <secFileNumber>000-32405</secFileNumber>
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                <ns2:street1>21823 30TH DRIVE SE</ns2:street1>
                <ns2:city>BOTHELL</ns2:city>
                <ns2:stateOrCountry>WA</ns2:stateOrCountry>
                <ns2:zipCode>98021</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>(425) 527-4000</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>JEAN LIU</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>38th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>5000</noOfUnitsSold>
            <aggregateMarketValue>1029310.00</aggregateMarketValue>
            <noOfUnitsOutstanding>187113577</noOfUnitsOutstanding>
            <approxSaleDate>04/17/2023</approxSaleDate>
            <securitiesExchangeName>NASD</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <acquiredDate>08/25/2015</acquiredDate>
            <natureOfAcquisitionTransaction>STOCK OPTIONS</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>5000</amountOfSecuritiesAcquired>
            <paymentDate>08/25/2015</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
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                <address>
                    <ns2:street1>21823 30TH DRIVE SE</ns2:street1>
                    <ns2:city>BOTHELL</ns2:city>
                    <ns2:stateOrCountry>WA</ns2:stateOrCountry>
                    <ns2:zipCode>98021</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>04/06/2023</saleDate>
            <amountOfSecuritiesSold>174</amountOfSecuritiesSold>
            <grossProceeds>35798.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JEAN LIU</name>
                <address>
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                    <ns2:city>BOTHELL</ns2:city>
                    <ns2:stateOrCountry>WA</ns2:stateOrCountry>
                    <ns2:zipCode>98021</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>03/16/2023</saleDate>
            <amountOfSecuritiesSold>5000</amountOfSecuritiesSold>
            <grossProceeds>999292.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JEAN LIU</name>
                <address>
                    <ns2:street1>21823 30TH DRIVE SE</ns2:street1>
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                    <ns2:stateOrCountry>WA</ns2:stateOrCountry>
                    <ns2:zipCode>98021</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>02/16/2023</saleDate>
            <amountOfSecuritiesSold>5000</amountOfSecuritiesSold>
            <grossProceeds>774782.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JEAN LIU</name>
                <address>
                    <ns2:street1>21823 30TH DRIVE SE</ns2:street1>
                    <ns2:city>BOTHELL</ns2:city>
                    <ns2:stateOrCountry>WA</ns2:stateOrCountry>
                    <ns2:zipCode>98021</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>01/24/2023</saleDate>
            <amountOfSecuritiesSold>5000</amountOfSecuritiesSold>
            <grossProceeds>674918.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JEAN LIU</name>
                <address>
                    <ns2:street1>21823 30TH DRIVE SE</ns2:street1>
                    <ns2:city>BOTHELL</ns2:city>
                    <ns2:stateOrCountry>WA</ns2:stateOrCountry>
                    <ns2:zipCode>98021</ns2:zipCode>
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            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>01/17/2023</saleDate>
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            <grossProceeds>75536.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>04/17/2023</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>11/25/2022</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Jean I. Liu</signature>
        </noticeSignature>
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144
0001241357
XXXXXXXX
LIVE
0001060736
SEAGEN INC.
000-32405
21823 30TH DRIVE SE
BOTHELL
WA
98021
(425) 527-4000
JEAN LIU
Officer
Common
Morgan Stanley Smith Barney LLC
1 New York Plaza
38th Floor
New York
NY
10004
5000
1029310.00
187113577
04/17/2023
NASD
COMMON
08/25/2015
STOCK OPTIONS
ISSUER
N
5000
08/25/2015
Cash
N
JEAN LIU
21823 30TH DRIVE SE
BOTHELL
WA
98021
COMMON
04/06/2023
174
35798.00
JEAN LIU
21823 30TH DRIVE SE
BOTHELL
WA
98021
COMMON
03/16/2023
5000
999292.00
JEAN LIU
21823 30TH DRIVE SE
BOTHELL
WA
98021
COMMON
02/16/2023
5000
774782.00
JEAN LIU
21823 30TH DRIVE SE
BOTHELL
WA
98021
COMMON
01/24/2023
5000
674918.00
JEAN LIU
21823 30TH DRIVE SE
BOTHELL
WA
98021
COMMON
01/17/2023
578
75536.00
04/17/2023
11/25/2022
/s/ Jean I. Liu