<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001962731</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001594805</issuerCik>
            <issuerName>SHOPIFY, INC.</issuerName>
            <secFileNumber>001-37400</secFileNumber>
            <issuerAddress>
                <ns2:street1>151 O Connor Street</ns2:street1>
                <ns2:city>Ottawa</ns2:city>
                <ns2:stateOrCountry>A6</ns2:stateOrCountry>
                <ns2:zipCode>K2P 2L8</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>6132412828</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>JESSICA HERTZ</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>2273</noOfUnitsSold>
            <aggregateMarketValue>145062.86</aggregateMarketValue>
            <noOfUnitsOutstanding>1207318947</noOfUnitsOutstanding>
            <approxSaleDate>06/12/2024</approxSaleDate>
            <securitiesExchangeName>NYSE</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Class A Subordinate Voting Shares</securitiesClassTitle>
            <acquiredDate>06/09/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>2273</amountOfSecuritiesAcquired>
            <paymentDate>06/09/2024</paymentDate>
            <natureOfPayment>Vesting of RSUs</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JESSICA HERTZ</name>
                <address>
                    <ns2:street1>151 O Connor Street</ns2:street1>
                    <ns2:city>Ottawa</ns2:city>
                    <ns2:stateOrCountry>A6</ns2:stateOrCountry>
                    <ns2:zipCode>K2P 2L8</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>CL A Subordinate Voting Share</securitiesClassTitle>
            <saleDate>06/10/2024</saleDate>
            <amountOfSecuritiesSold>5688</amountOfSecuritiesSold>
            <grossProceeds>353902.81</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales for JESSICA HERTZ</name>
                <address>
                    <ns2:street1>151 O Connor Street</ns2:street1>
                    <ns2:city>Ottawa</ns2:city>
                    <ns2:stateOrCountry>A6</ns2:stateOrCountry>
                    <ns2:zipCode>K2P 2L8</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>05/29/2024</saleDate>
            <amountOfSecuritiesSold>2508</amountOfSecuritiesSold>
            <grossProceeds>144460.80</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JESSICA HERTZ</name>
                <address>
                    <ns2:street1>151 O Connor Street</ns2:street1>
                    <ns2:city>Ottawa</ns2:city>
                    <ns2:stateOrCountry>A6</ns2:stateOrCountry>
                    <ns2:zipCode>K2P 2L8</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>CL A Subordinate Voting Share</securitiesClassTitle>
            <saleDate>05/28/2024</saleDate>
            <amountOfSecuritiesSold>768</amountOfSecuritiesSold>
            <grossProceeds>43557.04</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JESSICA HERTZ</name>
                <address>
                    <ns2:street1>151 O Connor Street</ns2:street1>
                    <ns2:city>Ottawa</ns2:city>
                    <ns2:stateOrCountry>A6</ns2:stateOrCountry>
                    <ns2:zipCode>K2P 2L8</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>CL A Subordinate Voting Share</securitiesClassTitle>
            <saleDate>05/24/2024</saleDate>
            <amountOfSecuritiesSold>2435</amountOfSecuritiesSold>
            <grossProceeds>139267.15</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JESSICA HERTZ</name>
                <address>
                    <ns2:street1>151 O Connor Street</ns2:street1>
                    <ns2:city>Ottawa</ns2:city>
                    <ns2:stateOrCountry>A6</ns2:stateOrCountry>
                    <ns2:zipCode>K2P 2L8</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>CL A Subordinate Voting Share</securitiesClassTitle>
            <saleDate>04/29/2024</saleDate>
            <amountOfSecuritiesSold>761</amountOfSecuritiesSold>
            <grossProceeds>54671.46</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JESSICA HERTZ</name>
                <address>
                    <ns2:street1>151 O Connor Street</ns2:street1>
                    <ns2:city>Ottawa</ns2:city>
                    <ns2:stateOrCountry>A6</ns2:stateOrCountry>
                    <ns2:zipCode>K2P 2L8</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>CL A Subordinate Voting Share</securitiesClassTitle>
            <saleDate>03/28/2024</saleDate>
            <amountOfSecuritiesSold>764</amountOfSecuritiesSold>
            <grossProceeds>60227.27</grossProceeds>
        </securitiesSoldInPast3Months>
        <remarks>Aggregate market value calculated using 6/11/2024 closing price of $63.82 per share. Number of shares outstanding as of June 12, 2024. Shares to be sold to cover taxes and fees resulting from the vesting of RSUs. Dates of sale reflect a three month period starting on June 12, 2024.</remarks>
        <noticeSignature>
            <noticeDate>06/12/2024</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>06/09/2023</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Jessica Rose Hertz</signature>
        </noticeSignature>
    </formData>
</edgarSubmission>
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144
0001962731
XXXXXXXX
LIVE
0001594805
SHOPIFY, INC.
001-37400
151 O Connor Street
Ottawa
A6
K2P 2L8
6132412828
JESSICA HERTZ
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
2273
145062.86
1207318947
06/12/2024
NYSE
Class A Subordinate Voting Shares
06/09/2024
Restricted Stock Units
Issuer
N
2273
06/09/2024
Vesting of RSUs
N
JESSICA HERTZ
151 O Connor Street
Ottawa
A6
K2P 2L8
CL A Subordinate Voting Share
06/10/2024
5688
353902.81
10b5-1 Sales for JESSICA HERTZ
151 O Connor Street
Ottawa
A6
K2P 2L8
Common
05/29/2024
2508
144460.80
JESSICA HERTZ
151 O Connor Street
Ottawa
A6
K2P 2L8
CL A Subordinate Voting Share
05/28/2024
768
43557.04
JESSICA HERTZ
151 O Connor Street
Ottawa
A6
K2P 2L8
CL A Subordinate Voting Share
05/24/2024
2435
139267.15
JESSICA HERTZ
151 O Connor Street
Ottawa
A6
K2P 2L8
CL A Subordinate Voting Share
04/29/2024
761
54671.46
JESSICA HERTZ
151 O Connor Street
Ottawa
A6
K2P 2L8
CL A Subordinate Voting Share
03/28/2024
764
60227.27
Aggregate market value calculated using 6/11/2024 closing price of $63.82 per share. Number of shares outstanding as of June 12, 2024. Shares to be sold to cover taxes and fees resulting from the vesting of RSUs. Dates of sale reflect a three month period starting on June 12, 2024.
06/12/2024
06/09/2023
/s/ Jessica Rose Hertz