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            <secFileNumber>001-32335</secFileNumber>
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                <ns2:city>San Diego</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>92130</ns2:zipCode>
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            <issuerContactPhone>(858) 794-8889</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>HELEN TORLEY</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
                <relationshipToIssuer>Director</relationshipToIssuer>
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            <brokerOrMarketmakerDetails>
                <name>E*TRADE FINANCIAL CORPORATION</name>
                <address>
                    <ns2:street1>3 EDISON DRIVE</ns2:street1>
                    <ns2:city>ALPHARETTA</ns2:city>
                    <ns2:stateOrCountry>GA</ns2:stateOrCountry>
                    <ns2:zipCode>30005</ns2:zipCode>
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            <noOfUnitsOutstanding>131920880</noOfUnitsOutstanding>
            <approxSaleDate>08/29/2023</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
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            <acquiredDate>08/29/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Stock Option Exercise</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
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            <paymentDate>08/29/2023</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
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                    <ns2:zipCode>92130</ns2:zipCode>
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            <amountOfSecuritiesSold>10000</amountOfSecuritiesSold>
            <grossProceeds>431819.00</grossProceeds>
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            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>08/15/2023</saleDate>
            <amountOfSecuritiesSold>10000</amountOfSecuritiesSold>
            <grossProceeds>437683.00</grossProceeds>
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        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>HELEN TORLEY</name>
                <address>
                    <ns2:street1>12390 El Camino Real</ns2:street1>
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                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>92130</ns2:zipCode>
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            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>07/27/2023</saleDate>
            <amountOfSecuritiesSold>10000</amountOfSecuritiesSold>
            <grossProceeds>437903.00</grossProceeds>
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                <name>HELEN TORLEY</name>
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                    <ns2:street1>12390 El Camino Real</ns2:street1>
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                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>92130</ns2:zipCode>
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        <noticeSignature>
            <noticeDate>08/29/2023</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>09/07/2022</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Helen Imelda Torley</signature>
        </noticeSignature>
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144
0001528185
XXXXXXXX
LIVE
0001159036
HALOZYME THERAPEUTICS, INC.
001-32335
12390 El Camino Real
San Diego
CA
92130
(858) 794-8889
HELEN TORLEY
Officer
Director
Common
E*TRADE FINANCIAL CORPORATION
3 EDISON DRIVE
ALPHARETTA
GA
30005
10000
424018.00
131920880
08/29/2023
NASDAQ
COMMON
08/29/2023
Stock Option Exercise
ISSUER
N
10000
08/29/2023
Cash
N
HELEN TORLEY
12390 El Camino Real
San Diego
CA
92130
Common
08/17/2023
10000
431819.00
HELEN TORLEY
12390 El Camino Real
San Diego
CA
92130
Common
08/16/2023
10000
435320.00
HELEN TORLEY
12390 El Camino Real
San Diego
CA
92130
Common
08/15/2023
10000
437683.00
HELEN TORLEY
12390 El Camino Real
San Diego
CA
92130
Common
07/27/2023
10000
437903.00
HELEN TORLEY
12390 El Camino Real
San Diego
CA
92130
Common
07/26/2023
10000
426890.00
HELEN TORLEY
12390 El Camino Real
San Diego
CA
92130
Common
07/25/2023
10000
427962.00
08/29/2023
09/07/2022
/s/ Helen Imelda Torley