<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001228622</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001517413</issuerCik>
            <issuerName>FASTLY, INC.</issuerName>
            <secFileNumber>001-38897</secFileNumber>
            <issuerAddress>
                <ns2:street1>475 Brannan Street, Suite 300</ns2:street1>
                <ns2:city>San Francisco</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>94107</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>8444327859</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>RONALD KISLING LIVING TRUST U/A DTD 07/15/2016</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>24500</noOfUnitsSold>
            <aggregateMarketValue>233975.00</aggregateMarketValue>
            <noOfUnitsOutstanding>140300000</noOfUnitsOutstanding>
            <approxSaleDate>01/06/2025</approxSaleDate>
            <securitiesExchangeName>NYSE</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>07/15/2022</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>24500</amountOfSecuritiesAcquired>
            <paymentDate>07/15/2022</paymentDate>
            <natureOfPayment>N/A</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>RONALD KISLING TTEERONALD KISLING LIVING TRUST U/A DTD07/15/2016</name>
                <address>
                    <ns2:street1>475 Brannan Street, Suite 300</ns2:street1>
                    <ns2:city>San Francisco</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94107</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>12/02/2024</saleDate>
            <amountOfSecuritiesSold>1192</amountOfSecuritiesSold>
            <grossProceeds>10990.24</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>RONALD KISLING TTEERONALD KISLING LIVING TRUST U/A DTD07/15/2016</name>
                <address>
                    <ns2:street1>475 Brannan Street, Suite 300</ns2:street1>
                    <ns2:city>San Francisco</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94107</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>11/25/2024</saleDate>
            <amountOfSecuritiesSold>2920</amountOfSecuritiesSold>
            <grossProceeds>23710.40</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>RONALD KISLING TTEERONALD KISLING LIVING TRUST U/A DTD07/15/2016</name>
                <address>
                    <ns2:street1>475 Brannan Street, Suite 300</ns2:street1>
                    <ns2:city>San Francisco</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94107</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>11/18/2024</saleDate>
            <amountOfSecuritiesSold>16102</amountOfSecuritiesSold>
            <grossProceeds>100637.50</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>RONALD KISLING TTEERONALD KISLING LIVING TRUST U/A DTD07/15/2016</name>
                <address>
                    <ns2:street1>475 Brannan Street, Suite 300</ns2:street1>
                    <ns2:city>San Francisco</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94107</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>10/16/2024</saleDate>
            <amountOfSecuritiesSold>7449</amountOfSecuritiesSold>
            <grossProceeds>53930.76</grossProceeds>
        </securitiesSoldInPast3Months>
        <remarks>The securities to be sold were acquired upon the vesting of restricted stock units during the period of 7/15/2022 through 11/28/2023.
</remarks>
        <noticeSignature>
            <noticeDate>01/06/2025</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>09/05/2024</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Ronald Kisling</signature>
        </noticeSignature>
    </formData>
</edgarSubmission>
[{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 6525}]
144
0001228622
XXXXXXXX
LIVE
0001517413
FASTLY, INC.
001-38897
475 Brannan Street, Suite 300
San Francisco
CA
94107
8444327859
RONALD KISLING LIVING TRUST U/A DTD 07/15/2016
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
24500
233975.00
140300000
01/06/2025
NYSE
Common
07/15/2022
Restricted Stock Units
Issuer
N
24500
07/15/2022
N/A
N
RONALD KISLING TTEERONALD KISLING LIVING TRUST U/A DTD07/15/2016
475 Brannan Street, Suite 300
San Francisco
CA
94107
Common
12/02/2024
1192
10990.24
RONALD KISLING TTEERONALD KISLING LIVING TRUST U/A DTD07/15/2016
475 Brannan Street, Suite 300
San Francisco
CA
94107
Common
11/25/2024
2920
23710.40
RONALD KISLING TTEERONALD KISLING LIVING TRUST U/A DTD07/15/2016
475 Brannan Street, Suite 300
San Francisco
CA
94107
Common
11/18/2024
16102
100637.50
RONALD KISLING TTEERONALD KISLING LIVING TRUST U/A DTD07/15/2016
475 Brannan Street, Suite 300
San Francisco
CA
94107
Common
10/16/2024
7449
53930.76
The securities to be sold were acquired upon the vesting of restricted stock units during the period of 7/15/2022 through 11/28/2023.
01/06/2025
09/05/2024
/s/ Ronald Kisling