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  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0002066411</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0000858877</issuerCik>
      <issuerName>CISCO SYSTEMS, INC.</issuerName>
      <secFileNumber>001-39940</secFileNumber>
      <issuerAddress>
        <com:street1>170 WEST TASMAN DR</com:street1>
        <com:city>SAN JOSE</com:city>
        <com:stateOrCountry>CA</com:stateOrCountry>
        <com:zipCode>95134-1706</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>4085264000</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Tuszik Oliver</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Officer</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Charles Schwab &amp; Co., Inc.</name>
        <address>
          <com:street1>3000 Schwab Way</com:street1>
          <com:city>Westlake</com:city>
          <com:stateOrCountry>TX</com:stateOrCountry>
          <com:zipCode>76262</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>15000</noOfUnitsSold>
      <aggregateMarketValue>952947.00</aggregateMarketValue>
      <noOfUnitsOutstanding>3959998180</noOfUnitsOutstanding>
      <approxSaleDate>05/28/2025</approxSaleDate>
      <securitiesExchangeName>NASDAQ</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <acquiredDate>05/10/2024</acquiredDate>
      <natureOfAcquisitionTransaction>RSU / PSU - see remarks</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>CISCO SYSTEMS, INC.</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>15000</amountOfSecuritiesAcquired>
      <paymentDate>05/10/2024</paymentDate>
      <natureOfPayment>Equity Compensation</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <remarks>The shares sold in this filing were acquired and paid for between 5/10/2024 and 11/11/2024.</remarks>
    <noticeSignature>
      <noticeDate>05/28/2025</noticeDate>
      <signature>/S/ Oliver Tuszik</signature>
    </noticeSignature>
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144
0002066411
XXXXXXXX
LIVE
0000858877
CISCO SYSTEMS, INC.
001-39940
170 WEST TASMAN DR
SAN JOSE
CA
95134-1706
4085264000
Tuszik Oliver
Officer
Common
Charles Schwab & Co., Inc.
3000 Schwab Way
Westlake
TX
76262
15000
952947.00
3959998180
05/28/2025
NASDAQ
Common
05/10/2024
RSU / PSU - see remarks
CISCO SYSTEMS, INC.
N
15000
05/10/2024
Equity Compensation
Y
The shares sold in this filing were acquired and paid for between 5/10/2024 and 11/11/2024.
05/28/2025
/S/ Oliver Tuszik