<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001838061</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001789972</issuerCik>
            <issuerName>CULLINAN THERAPEUTICS, INC.</issuerName>
            <secFileNumber>001-39856</secFileNumber>
            <issuerAddress>
                <ns2:street1>One Main Street, Suite 1350</ns2:street1>
                <ns2:city>Cambridge</ns2:city>
                <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                <ns2:zipCode>02142</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>6174104650</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>JENNIFER MICHAELSON</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>8000</noOfUnitsSold>
            <aggregateMarketValue>101440.00</aggregateMarketValue>
            <noOfUnitsOutstanding>58227593</noOfUnitsOutstanding>
            <approxSaleDate>01/06/2025</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>12/16/2019</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>4523</amountOfSecuritiesAcquired>
            <paymentDate>12/16/2019</paymentDate>
            <natureOfPayment>N/A</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>01/06/2025</acquiredDate>
            <natureOfAcquisitionTransaction>Exercise of Stock Options</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>3477</amountOfSecuritiesAcquired>
            <paymentDate>01/06/2025</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JENNIFER MICHAELSON </name>
                <address>
                    <ns2:street1>One Main Street, Suite 1350</ns2:street1>
                    <ns2:city>Cambridge</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02142</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>12/18/2024</saleDate>
            <amountOfSecuritiesSold>4693</amountOfSecuritiesSold>
            <grossProceeds>53547.13</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>JENNIFER MICHAELSON </name>
                <address>
                    <ns2:street1>One Main Street, Suite 1350</ns2:street1>
                    <ns2:city>Cambridge</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02142</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>12/12/2024</saleDate>
            <amountOfSecuritiesSold>3489</amountOfSecuritiesSold>
            <grossProceeds>43682.28</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales for JENNIFER MICHAELSON </name>
                <address>
                    <ns2:street1>One Main Street, Suite 1350</ns2:street1>
                    <ns2:city>Cambridge</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02142</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>11/05/2024</saleDate>
            <amountOfSecuritiesSold>8000</amountOfSecuritiesSold>
            <grossProceeds>125102.80</grossProceeds>
        </securitiesSoldInPast3Months>
        <remarks>The securities to be sold were acquired upon the vesting of restricted stock units during the period of 12/16/2023 through 12/17/2023
The securities to be sold will be received upon the exercise of stock options over the next three months. The dates of acquisition and payment will be the dates of exercise/sale.</remarks>
        <noticeSignature>
            <noticeDate>01/06/2025</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>01/05/2024</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Jennifer Michaelson</signature>
        </noticeSignature>
    </formData>
</edgarSubmission>
[{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 6386}]
144
0001838061
XXXXXXXX
LIVE
0001789972
CULLINAN THERAPEUTICS, INC.
001-39856
One Main Street, Suite 1350
Cambridge
MA
02142
6174104650
JENNIFER MICHAELSON
Officer
COMMON
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
8000
101440.00
58227593
01/06/2025
NASDAQ
Common
12/16/2019
Restricted Stock Units
Issuer
N
4523
12/16/2019
N/A
Common
01/06/2025
Exercise of Stock Options
Issuer
N
3477
01/06/2025
Cash
N
JENNIFER MICHAELSON
One Main Street, Suite 1350
Cambridge
MA
02142
Common
12/18/2024
4693
53547.13
JENNIFER MICHAELSON
One Main Street, Suite 1350
Cambridge
MA
02142
Common
12/12/2024
3489
43682.28
10b5-1 Sales for JENNIFER MICHAELSON
One Main Street, Suite 1350
Cambridge
MA
02142
COMMON
11/05/2024
8000
125102.80
The securities to be sold were acquired upon the vesting of restricted stock units during the period of 12/16/2023 through 12/17/2023
The securities to be sold will be received upon the exercise of stock options over the next three months. The dates of acquisition and payment will be the dates of exercise/sale.
01/06/2025
01/05/2024
/s/ Jennifer Michaelson