<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001838061</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001789972</issuerCik>
            <issuerName>CULLINAN THERAPEUTICS, INC.</issuerName>
            <secFileNumber>001-39856</secFileNumber>
            <issuerAddress>
                <ns2:street1>One Main Street, Suite 1350</ns2:street1>
                <ns2:city>Cambridge</ns2:city>
                <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                <ns2:zipCode>02142</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>6174104650</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>JENNIFER MICHAELSON &amp; MARC D MICHAELSON</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>66000</noOfUnitsSold>
            <aggregateMarketValue>1871100.00</aggregateMarketValue>
            <noOfUnitsOutstanding>43065645</noOfUnitsOutstanding>
            <approxSaleDate>05/06/2024</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>05/06/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Exercise of Stock Options</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>50000</amountOfSecuritiesAcquired>
            <paymentDate>05/06/2024</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>12/01/2018</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>16000</amountOfSecuritiesAcquired>
            <paymentDate>12/01/2018</paymentDate>
            <natureOfPayment>N/A</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <remarks>The securities to be sold were and will be received upon the exercise of stock options over the next three months.
The date of acquisition and payment were and will be the date of exercise/sale.
The securities to be sold were acquired upon the vesting of restricted stock units during the period of 12/01/2018 through 6/17/2023.
</remarks>
        <noticeSignature>
            <noticeDate>05/06/2024</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>01/05/2024</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Jennifer Michaelson</signature>
        </noticeSignature>
    </formData>
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144
0001838061
XXXXXXXX
LIVE
0001789972
CULLINAN THERAPEUTICS, INC.
001-39856
One Main Street, Suite 1350
Cambridge
MA
02142
6174104650
JENNIFER MICHAELSON & MARC D MICHAELSON
Officer
COMMON
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
66000
1871100.00
43065645
05/06/2024
NASDAQ
Common
05/06/2024
Exercise of Stock Options
Issuer
N
50000
05/06/2024
Cash
Common
12/01/2018
Restricted Stock Units
Issuer
N
16000
12/01/2018
N/A
Y
The securities to be sold were and will be received upon the exercise of stock options over the next three months.
The date of acquisition and payment were and will be the date of exercise/sale.
The securities to be sold were acquired upon the vesting of restricted stock units during the period of 12/01/2018 through 6/17/2023.
05/06/2024
01/05/2024
/s/ Jennifer Michaelson