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    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001924892</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001809519</issuerCik>
            <issuerName>GOODRX HOLDINGS, INC.</issuerName>
            <secFileNumber>001-39549</secFileNumber>
            <issuerAddress>
                <ns2:street1>2701 Olympic Boulevard</ns2:street1>
                <ns2:city>Santa Monica</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>90404</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>855 268-2822</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>ROMIN NABIEY</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
                <relationshipToIssuer>Director</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>79000</noOfUnitsSold>
            <aggregateMarketValue>534624.60</aggregateMarketValue>
            <noOfUnitsOutstanding>98583716</noOfUnitsOutstanding>
            <approxSaleDate>08/12/2024</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>common</securitiesClassTitle>
            <acquiredDate>03/08/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>6456</amountOfSecuritiesAcquired>
            <paymentDate>03/08/2024</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>common</securitiesClassTitle>
            <acquiredDate>05/08/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>8144</amountOfSecuritiesAcquired>
            <paymentDate>05/08/2024</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>common</securitiesClassTitle>
            <acquiredDate>07/15/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>1704</amountOfSecuritiesAcquired>
            <paymentDate>07/15/2023</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>common</securitiesClassTitle>
            <acquiredDate>04/15/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>1676</amountOfSecuritiesAcquired>
            <paymentDate>04/15/2024</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>common</securitiesClassTitle>
            <acquiredDate>01/15/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>1538</amountOfSecuritiesAcquired>
            <paymentDate>01/15/2024</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>common</securitiesClassTitle>
            <acquiredDate>07/15/2022</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>1704</amountOfSecuritiesAcquired>
            <paymentDate>07/15/2022</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>common</securitiesClassTitle>
            <acquiredDate>04/15/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>1704</amountOfSecuritiesAcquired>
            <paymentDate>04/15/2023</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>common</securitiesClassTitle>
            <acquiredDate>08/26/2020</acquiredDate>
            <natureOfAcquisitionTransaction>Exercise of options under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>14583</amountOfSecuritiesAcquired>
            <paymentDate>08/26/2020</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>common</securitiesClassTitle>
            <acquiredDate>03/17/2022</acquiredDate>
            <natureOfAcquisitionTransaction>Exercise of options under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>6148</amountOfSecuritiesAcquired>
            <paymentDate>03/17/2022</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>common</securitiesClassTitle>
            <acquiredDate>09/08/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>6673</amountOfSecuritiesAcquired>
            <paymentDate>09/08/2023</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>common</securitiesClassTitle>
            <acquiredDate>02/08/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>7473</amountOfSecuritiesAcquired>
            <paymentDate>02/08/2024</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>common</securitiesClassTitle>
            <acquiredDate>06/08/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>7996</amountOfSecuritiesAcquired>
            <paymentDate>06/08/2024</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>common</securitiesClassTitle>
            <acquiredDate>08/08/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>8283</amountOfSecuritiesAcquired>
            <paymentDate>08/08/2023</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>common</securitiesClassTitle>
            <acquiredDate>04/15/2022</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>1704</amountOfSecuritiesAcquired>
            <paymentDate>04/15/2022</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>common</securitiesClassTitle>
            <acquiredDate>01/15/2022</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>1538</amountOfSecuritiesAcquired>
            <paymentDate>01/15/2022</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>common</securitiesClassTitle>
            <acquiredDate>07/15/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>1676</amountOfSecuritiesAcquired>
            <paymentDate>07/15/2024</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>08/12/2024</noticeDate>
            <planAdoptionDates/>
            <signature>/s/ Romin Nabiey</signature>
        </noticeSignature>
    </formData>
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144
0001924892
XXXXXXXX
LIVE
0001809519
GOODRX HOLDINGS, INC.
001-39549
2701 Olympic Boulevard
Santa Monica
CA
90404
855 268-2822
ROMIN NABIEY
Officer
Director
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
79000
534624.60
98583716
08/12/2024
NASDAQ
common
03/08/2024
Restricted stock vesting under a registered plan
Issuer
N
6456
03/08/2024
Not Applicable
common
05/08/2024
Restricted stock vesting under a registered plan
Issuer
N
8144
05/08/2024
Not Applicable
common
07/15/2023
Restricted stock vesting under a registered plan
Issuer
N
1704
07/15/2023
Not Applicable
common
04/15/2024
Restricted stock vesting under a registered plan
Issuer
N
1676
04/15/2024
Not Applicable
common
01/15/2024
Restricted stock vesting under a registered plan
Issuer
N
1538
01/15/2024
Not Applicable
common
07/15/2022
Restricted stock vesting under a registered plan
Issuer
N
1704
07/15/2022
Not Applicable
common
04/15/2023
Restricted stock vesting under a registered plan
Issuer
N
1704
04/15/2023
Not Applicable
common
08/26/2020
Exercise of options under a registered plan
Issuer
N
14583
08/26/2020
Cash
common
03/17/2022
Exercise of options under a registered plan
Issuer
N
6148
03/17/2022
Cash
common
09/08/2023
Restricted stock vesting under a registered plan
Issuer
N
6673
09/08/2023
Not Applicable
common
02/08/2024
Restricted stock vesting under a registered plan
Issuer
N
7473
02/08/2024
Not Applicable
common
06/08/2024
Restricted stock vesting under a registered plan
Issuer
N
7996
06/08/2024
Not Applicable
common
08/08/2023
Restricted stock vesting under a registered plan
Issuer
N
8283
08/08/2023
Not Applicable
common
04/15/2022
Restricted stock vesting under a registered plan
Issuer
N
1704
04/15/2022
Not Applicable
common
01/15/2022
Restricted stock vesting under a registered plan
Issuer
N
1538
01/15/2022
Not Applicable
common
07/15/2024
Restricted stock vesting under a registered plan
Issuer
N
1676
07/15/2024
Not Applicable
Y
08/12/2024
/s/ Romin Nabiey