<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001446989</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0001099800</issuerCik>
      <issuerName>Edwards Lifesciences Corp</issuerName>
      <secFileNumber>001-15525</secFileNumber>
      <issuerAddress>
        <com:street1>ONE EDWARDS WAY</com:street1>
        <com:city>IRVINE</com:city>
        <com:stateOrCountry>CA</com:stateOrCountry>
        <com:zipCode>92614</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>9492502500</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Ullem Scott B.</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Officer</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Charles Schwab &amp; Co., Inc.</name>
        <address>
          <com:street1>3000 Schwab Way</com:street1>
          <com:city>Westlake</com:city>
          <com:stateOrCountry>TX</com:stateOrCountry>
          <com:zipCode>76262</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>21765</noOfUnitsSold>
      <aggregateMarketValue>1693099.00</aggregateMarketValue>
      <noOfUnitsOutstanding>607916300</noOfUnitsOutstanding>
      <approxSaleDate>08/31/2023</approxSaleDate>
      <securitiesExchangeName>NYSE</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <acquiredDate>08/31/2023</acquiredDate>
      <natureOfAcquisitionTransaction>Employee Stock Option Exercise - See Remarks</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>EDWARDS LIFESCIENCES CORPORATION</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>21765</amountOfSecuritiesAcquired>
      <paymentDate>08/31/2023</paymentDate>
      <natureOfPayment>Broker Payment for Cashless Exercise</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>SCOTT B ULLEM</name>
        <address>
          <com:street1>ONE EDWARDS WAY</com:street1>
          <com:city>IRVINE</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>92614</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Edwards Lifesciences Corp</securitiesClassTitle>
      <saleDate>06/30/2023</saleDate>
      <amountOfSecuritiesSold>7255</amountOfSecuritiesSold>
      <grossProceeds>676673.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>SCOTT B ULLEM</name>
        <address>
          <com:street1>ONE EDWARDS WAY</com:street1>
          <com:city>IRVINE</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>92614</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Edwards Lifesciences Corp</securitiesClassTitle>
      <saleDate>07/31/2023</saleDate>
      <amountOfSecuritiesSold>7255</amountOfSecuritiesSold>
      <grossProceeds>611959.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <remarks>The options covered by this filing, may be sold over various dates.</remarks>
    <noticeSignature>
      <noticeDate>08/31/2023</noticeDate>
      <planAdoptionDates>
        <planAdoptionDate>02/05/2023</planAdoptionDate>
      </planAdoptionDates>
      <signature>SCOTT B ULLEM</signature>
    </noticeSignature>
  </formData>
</edgarSubmission>
[{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 4173}]
144
0001446989
XXXXXXXX
LIVE
0001099800
Edwards Lifesciences Corp
001-15525
ONE EDWARDS WAY
IRVINE
CA
92614
9492502500
Ullem Scott B.
Officer
Common
Charles Schwab & Co., Inc.
3000 Schwab Way
Westlake
TX
76262
21765
1693099.00
607916300
08/31/2023
NYSE
Common
08/31/2023
Employee Stock Option Exercise - See Remarks
EDWARDS LIFESCIENCES CORPORATION
N
21765
08/31/2023
Broker Payment for Cashless Exercise
N
SCOTT B ULLEM
ONE EDWARDS WAY
IRVINE
CA
92614
Edwards Lifesciences Corp
06/30/2023
7255
676673.00
SCOTT B ULLEM
ONE EDWARDS WAY
IRVINE
CA
92614
Edwards Lifesciences Corp
07/31/2023
7255
611959.00
The options covered by this filing, may be sold over various dates.
08/31/2023
02/05/2023
SCOTT B ULLEM