<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001820036</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001583107</issuerCik>
            <issuerName>THERAVANCE BIOPHARMA INC</issuerName>
            <secFileNumber>001-36033</secFileNumber>
            <issuerAddress>
                <ns2:street1>C/O THERAVANCE BIOPHARMA US, INC., 901 G</ns2:street1>
                <ns2:street2>ATEWAY BLVD</ns2:street2>
                <ns2:city>SOUTH SAN FRANCISCO</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>94080</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>650-808-6000</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>RICHARD A GRAHAM</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>38th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>2323</noOfUnitsSold>
            <aggregateMarketValue>27597.24</aggregateMarketValue>
            <noOfUnitsOutstanding>63225611</noOfUnitsOutstanding>
            <approxSaleDate>04/14/2023</approxSaleDate>
            <securitiesExchangeName>NASD</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <acquiredDate>08/20/2021</acquiredDate>
            <natureOfAcquisitionTransaction>RSU</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>973</amountOfSecuritiesAcquired>
            <paymentDate>08/20/2021</paymentDate>
            <natureOfPayment>NONE</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <acquiredDate>02/20/2022</acquiredDate>
            <natureOfAcquisitionTransaction>RSU</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>1350</amountOfSecuritiesAcquired>
            <paymentDate>02/20/2022</paymentDate>
            <natureOfPayment>NONE</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>RICHARD A GRAHAM</name>
                <address>
                    <ns2:street1>C/O THERAVANCE BIOPHARMA US, INC., 901 G</ns2:street1>
                    <ns2:street2>ATEWAY BLVD</ns2:street2>
                    <ns2:city>SOUTH SAN FRANCISCO</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94080</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>03/14/2023</saleDate>
            <amountOfSecuritiesSold>2323</amountOfSecuritiesSold>
            <grossProceeds>23903.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>RICHARD A GRAHAM</name>
                <address>
                    <ns2:street1>C/O THERAVANCE BIOPHARMA US, INC., 901 G</ns2:street1>
                    <ns2:street2>ATEWAY BLVD</ns2:street2>
                    <ns2:city>SOUTH SAN FRANCISCO</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94080</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>03/06/2023</saleDate>
            <amountOfSecuritiesSold>2323</amountOfSecuritiesSold>
            <grossProceeds>23276.00</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>04/14/2023</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>11/23/2022</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Richard Alan Graham</signature>
        </noticeSignature>
    </formData>
</edgarSubmission>
[{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 5480}]
144
0001820036
XXXXXXXX
LIVE
0001583107
THERAVANCE BIOPHARMA INC
001-36033
C/O THERAVANCE BIOPHARMA US, INC., 901 G
ATEWAY BLVD
SOUTH SAN FRANCISCO
CA
94080
650-808-6000
RICHARD A GRAHAM
Officer
Common
Morgan Stanley Smith Barney LLC
1 New York Plaza
38th Floor
New York
NY
10004
2323
27597.24
63225611
04/14/2023
NASD
COMMON
08/20/2021
RSU
ISSUER
N
973
08/20/2021
NONE
COMMON
02/20/2022
RSU
ISSUER
N
1350
02/20/2022
NONE
N
RICHARD A GRAHAM
C/O THERAVANCE BIOPHARMA US, INC., 901 G
ATEWAY BLVD
SOUTH SAN FRANCISCO
CA
94080
COMMON
03/14/2023
2323
23903.00
RICHARD A GRAHAM
C/O THERAVANCE BIOPHARMA US, INC., 901 G
ATEWAY BLVD
SOUTH SAN FRANCISCO
CA
94080
COMMON
03/06/2023
2323
23276.00
04/14/2023
11/23/2022
/s/ Richard Alan Graham