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            <issuerAddress>
                <ns2:street1>13011 McCallen Pass</ns2:street1>
                <ns2:street2>Building A Suite 100</ns2:street2>
                <ns2:city>Austin</ns2:city>
                <ns2:stateOrCountry>TX</ns2:stateOrCountry>
                <ns2:zipCode>78753</ns2:zipCode>
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            <issuerContactPhone>(650) 980-9190</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>BV369 TRUST</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Director</relationshipToIssuer>
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            <securitiesClassTitle>Common</securitiesClassTitle>
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                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>87473</noOfUnitsSold>
            <aggregateMarketValue>14793564.97</aggregateMarketValue>
            <noOfUnitsOutstanding>132020816</noOfUnitsOutstanding>
            <approxSaleDate>12/02/2024</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
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            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>11/20/2020</acquiredDate>
            <natureOfAcquisitionTransaction>Exercise of options under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>87473</amountOfSecuritiesAcquired>
            <paymentDate>11/20/2020</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>12/02/2024</noticeDate>
            <planAdoptionDates/>
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144
0001222287
XXXXXXXX
LIVE
0001604821
NATERA, INC.
001-37478
13011 McCallen Pass
Building A Suite 100
Austin
TX
78753
(650) 980-9190
BV369 TRUST
Director
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
87473
14793564.97
132020816
12/02/2024
NASDAQ
Common
11/20/2020
Exercise of options under a registered plan
Issuer
N
87473
11/20/2020
Cash
Y
12/02/2024
/s/ Roelof Botha