<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001469131</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001060955</issuerCik>
            <issuerName>ICON PLC</issuerName>
            <secFileNumber>333-08704</secFileNumber>
            <issuerAddress>
                <ns2:street1>South County Business Park</ns2:street1>
                <ns2:street2>Leopardstown</ns2:street2>
                <ns2:city>Dublin 18</ns2:city>
                <ns2:stateOrCountry>L2</ns2:stateOrCountry>
                <ns2:zipCode>D18 X5R3</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>353-1-291-2000</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>STEPHEN CUTLER</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>6007</noOfUnitsSold>
            <aggregateMarketValue>1935996.03</aggregateMarketValue>
            <noOfUnitsOutstanding>82495086</noOfUnitsOutstanding>
            <approxSaleDate>03/04/2024</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/03/2021</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>1319</amountOfSecuritiesAcquired>
            <paymentDate>03/03/2021</paymentDate>
            <natureOfPayment>Services Rendered</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/03/2021</acquiredDate>
            <natureOfAcquisitionTransaction>Performance Stock Units</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>1983</amountOfSecuritiesAcquired>
            <paymentDate>03/03/2021</paymentDate>
            <natureOfPayment>Services Rendered</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/03/2022</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>1345</amountOfSecuritiesAcquired>
            <paymentDate>03/06/2024</paymentDate>
            <natureOfPayment>Services Rendered</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/03/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted stock vesting under a registered plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>1360</amountOfSecuritiesAcquired>
            <paymentDate>03/06/2024</paymentDate>
            <natureOfPayment>Services Rendered</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <remarks>Date of Plan Adoption or Giving of Instruction, if Relying on Rule 10b5-1

ATTENTION:
17 September 2023
The person for whose account the securities to which this notice relates are to be sold hereby
represents by signing this notice that he does not know any material adverse information in regard
to the current and prospective operations of the Issuer of the securities to be sold which has not
been publicly disclosed. If such person has adopted a written trading plan or given trading
instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the
date that the plan was adopted or the instruction given, that person makes such representation as
of the plan adoption or instruction date.
</remarks>
        <noticeSignature>
            <noticeDate>03/04/2024</noticeDate>
            <planAdoptionDates/>
            <signature>/s/ Stephen Cutler</signature>
        </noticeSignature>
    </formData>
</edgarSubmission>
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144
0001469131
XXXXXXXX
LIVE
0001060955
ICON PLC
333-08704
South County Business Park
Leopardstown
Dublin 18
L2
D18 X5R3
353-1-291-2000
STEPHEN CUTLER
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
6007
1935996.03
82495086
03/04/2024
NASDAQ
Common
03/03/2021
Restricted stock vesting under a registered plan
Issuer
N
1319
03/03/2021
Services Rendered
Common
03/03/2021
Performance Stock Units
Issuer
N
1983
03/03/2021
Services Rendered
Common
03/03/2022
Restricted stock vesting under a registered plan
Issuer
N
1345
03/06/2024
Services Rendered
Common
03/03/2023
Restricted stock vesting under a registered plan
Issuer
N
1360
03/06/2024
Services Rendered
Y
Date of Plan Adoption or Giving of Instruction, if Relying on Rule 10b5-1

ATTENTION:
17 September 2023
The person for whose account the securities to which this notice relates are to be sold hereby
represents by signing this notice that he does not know any material adverse information in regard
to the current and prospective operations of the Issuer of the securities to be sold which has not
been publicly disclosed. If such person has adopted a written trading plan or given trading
instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the
date that the plan was adopted or the instruction given, that person makes such representation as
of the plan adoption or instruction date.
03/04/2024
/s/ Stephen Cutler