<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001070123</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0001289945</issuerCik>
      <issuerName>Spok Holdings, Inc</issuerName>
      <secFileNumber>001-32358</secFileNumber>
      <issuerAddress>
        <com:street1>5911 KINGSTOWNE VILLAGE PARKWAY</com:street1>
        <com:street2>6TH FLOOR</com:street2>
        <com:city>ALEXANDRIA</com:city>
        <com:stateOrCountry>VA</com:stateOrCountry>
        <com:zipCode>22315</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>800-611-8488</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>WALLACE MICHAEL W</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Director</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>common</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Charles Schwab Corp</name>
        <address>
          <com:street1>3000 Schwab Way</com:street1>
          <com:city>Westlake</com:city>
          <com:stateOrCountry>TX</com:stateOrCountry>
          <com:zipCode>76262</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>25000</noOfUnitsSold>
      <aggregateMarketValue>367500.00</aggregateMarketValue>
      <noOfUnitsOutstanding>20264055</noOfUnitsOutstanding>
      <approxSaleDate>08/20/2024</approxSaleDate>
      <securitiesExchangeName>NASDAQ</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <acquiredDate>10/13/2019</acquiredDate>
      <natureOfAcquisitionTransaction>Purchased</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>8000</amountOfSecuritiesAcquired>
      <paymentDate>10/13/2019</paymentDate>
      <natureOfPayment>cash</natureOfPayment>
    </securitiesToBeSold>
    <securitiesToBeSold>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <acquiredDate>07/17/2018</acquiredDate>
      <natureOfAcquisitionTransaction>Stock Plan</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>17577</amountOfSecuritiesAcquired>
      <paymentDate>07/17/2018</paymentDate>
      <natureOfPayment>N/A</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <remarks>8,000 purchase-10/30/2019 3000 shs - 3/9/2020 2000 shs - 8/3/2020 3000 shs --
RSU - 7/17/2018 6881 shs - 1/2/2019 3064 shs - 1/11/2019 - 7632 shs</remarks>
    <noticeSignature>
      <noticeDate>08/20/2024</noticeDate>
      <signature>MICHAEL W WALLACE</signature>
    </noticeSignature>
  </formData>
</edgarSubmission>
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144
0001070123
XXXXXXXX
LIVE
0001289945
Spok Holdings, Inc
001-32358
5911 KINGSTOWNE VILLAGE PARKWAY
6TH FLOOR
ALEXANDRIA
VA
22315
800-611-8488
WALLACE MICHAEL W
Director
common
Charles Schwab Corp
3000 Schwab Way
Westlake
TX
76262
25000
367500.00
20264055
08/20/2024
NASDAQ
Common
10/13/2019
Purchased
Issuer
N
8000
10/13/2019
cash
Common
07/17/2018
Stock Plan
Issuer
N
17577
07/17/2018
N/A
Y
8,000 purchase-10/30/2019 3000 shs - 3/9/2020 2000 shs - 8/3/2020 3000 shs --
RSU - 7/17/2018 6881 shs - 1/2/2019 3064 shs - 1/11/2019 - 7632 shs
08/20/2024
MICHAEL W WALLACE