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            <filer>
                <filerCredentials>
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                    <ccc>XXXXXXXX</ccc>
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            <liveTestFlag>LIVE</liveTestFlag>



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        <issuerInfo>
            <issuerCik>0001478320</issuerCik>
            <issuerName>ADAPTIVE BIOTECHNOLOGIES CORPORATION</issuerName>
            <secFileNumber>001-38957</secFileNumber>
            <issuerAddress>
                <ns2:street1>1165 Eastlake Avenue East</ns2:street1>
                <ns2:city>Seattle</ns2:city>
                <ns2:stateOrCountry>WA</ns2:stateOrCountry>
                <ns2:zipCode>98109</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>(206) 659-0067</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>MICHELLE GRIFFIN</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Director</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>15664</noOfUnitsSold>
            <aggregateMarketValue>124439.52</aggregateMarketValue>
            <noOfUnitsOutstanding>148582201</noOfUnitsOutstanding>
            <approxSaleDate>03/06/2025</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/04/2025</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>ISSUER</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>15664</amountOfSecuritiesAcquired>
            <paymentDate>03/04/2025</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>03/06/2025</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>11/18/2024</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Michelle Renee Griffin</signature>
        </noticeSignature>
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144
0001229765
XXXXXXXX
LIVE
0001478320
ADAPTIVE BIOTECHNOLOGIES CORPORATION
001-38957
1165 Eastlake Avenue East
Seattle
WA
98109
(206) 659-0067
MICHELLE GRIFFIN
Director
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
15664
124439.52
148582201
03/06/2025
NASDAQ
Common
03/04/2025
Restricted Stock
ISSUER
N
15664
03/04/2025
Not Applicable
Y
03/06/2025
11/18/2024
/s/ Michelle Renee Griffin