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                    <ccc>XXXXXXXX</ccc>
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            <liveTestFlag>LIVE</liveTestFlag>



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        <issuerInfo>
            <issuerCik>0001706431</issuerCik>
            <issuerName>VIR BIOTECHNOLOGY, INC.</issuerName>
            <secFileNumber>001-39083</secFileNumber>
            <issuerAddress>
                <ns2:street1>499 Illinois Street, Suite 500</ns2:street1>
                <ns2:city>San Francisco</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>94158</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>(415) 906-4324</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>STEVEN J RICE</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>E*TRADE FINANCIAL CORPORATION</name>
                <address>
                    <ns2:street1>3 EDISON DRIVE</ns2:street1>
                    <ns2:city>ALPHARETTA</ns2:city>
                    <ns2:stateOrCountry>GA</ns2:stateOrCountry>
                    <ns2:zipCode>30005</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>2500</noOfUnitsSold>
            <aggregateMarketValue>64175.00</aggregateMarketValue>
            <noOfUnitsOutstanding>133976538</noOfUnitsOutstanding>
            <approxSaleDate>06/01/2023</approxSaleDate>
            <securitiesExchangeName>NASD</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>02/16/2022</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>2500</amountOfSecuritiesAcquired>
            <paymentDate>02/16/2022</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>06/01/2023</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>03/02/2023</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Steven Joseph Rice</signature>
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144
0001820108
XXXXXXXX
LIVE
0001706431
VIR BIOTECHNOLOGY, INC.
001-39083
499 Illinois Street, Suite 500
San Francisco
CA
94158
(415) 906-4324
STEVEN J RICE
Officer
Common
E*TRADE FINANCIAL CORPORATION
3 EDISON DRIVE
ALPHARETTA
GA
30005
2500
64175.00
133976538
06/01/2023
NASD
Common
02/16/2022
Restricted Stock
Issuer
N
2500
02/16/2022
Not Applicable
Y
06/01/2023
03/02/2023
/s/ Steven Joseph Rice