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            <liveTestFlag>LIVE</liveTestFlag>



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        <issuerInfo>
            <issuerCik>0001549595</issuerCik>
            <issuerName>NURIX THERAPEUTICS INC</issuerName>
            <secFileNumber>001-39398</secFileNumber>
            <issuerAddress>
                <ns2:street1>1700 Owens Street, Suite 205</ns2:street1>
                <ns2:city>San Francisco</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>94158</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>4156605320</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>CHRISTINE RING</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>9050</noOfUnitsSold>
            <aggregateMarketValue>203353.50</aggregateMarketValue>
            <noOfUnitsOutstanding>64411870</noOfUnitsOutstanding>
            <approxSaleDate>10/01/2024</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>10/01/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Exercise of Stock Options</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>9050</amountOfSecuritiesAcquired>
            <paymentDate>10/01/2024</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales for CHRISTINE RING</name>
                <address>
                    <ns2:street1>1700 Owens Street, Suite 205</ns2:street1>
                    <ns2:city>San Francisco</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94158</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>09/03/2024</saleDate>
            <amountOfSecuritiesSold>9050</amountOfSecuritiesSold>
            <grossProceeds>225736.11</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales for CHRISTINE RING</name>
                <address>
                    <ns2:street1>1700 Owens Street, Suite 205</ns2:street1>
                    <ns2:city>San Francisco</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94158</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>08/26/2024</saleDate>
            <amountOfSecuritiesSold>9870</amountOfSecuritiesSold>
            <grossProceeds>246842.78</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>10b5-1 Sales for CHRISTINE RING</name>
                <address>
                    <ns2:street1>1700 Owens Street, Suite 205</ns2:street1>
                    <ns2:city>San Francisco</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94158</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>08/01/2024</saleDate>
            <amountOfSecuritiesSold>5760</amountOfSecuritiesSold>
            <grossProceeds>123458.69</grossProceeds>
        </securitiesSoldInPast3Months>
        <remarks>The securities to be sold were and will be received upon the exercise of stock options over the next three months. The dates of acquisition and payment were and will be the dates of exercise/sale.&#13;
</remarks>
        <noticeSignature>
            <noticeDate>10/01/2024</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>02/29/2024</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Christine Ring</signature>
        </noticeSignature>
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144
0001817199
XXXXXXXX
LIVE
0001549595
NURIX THERAPEUTICS INC
001-39398
1700 Owens Street, Suite 205
San Francisco
CA
94158
4156605320
CHRISTINE RING
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
9050
203353.50
64411870
10/01/2024
NASDAQ
Common
10/01/2024
Exercise of Stock Options
Issuer
N
9050
10/01/2024
Cash
N
10b5-1 Sales for CHRISTINE RING
1700 Owens Street, Suite 205
San Francisco
CA
94158
Common
09/03/2024
9050
225736.11
10b5-1 Sales for CHRISTINE RING
1700 Owens Street, Suite 205
San Francisco
CA
94158
Common
08/26/2024
9870
246842.78
10b5-1 Sales for CHRISTINE RING
1700 Owens Street, Suite 205
San Francisco
CA
94158
Common
08/01/2024
5760
123458.69
The securities to be sold were and will be received upon the exercise of stock options over the next three months. The dates of acquisition and payment were and will be the dates of exercise/sale.
10/01/2024
02/29/2024
/s/ Christine Ring