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    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001909680</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001841387</issuerCik>
            <issuerName>CANDEL THERAPEUTICS INC</issuerName>
            <secFileNumber>001-40629</secFileNumber>
            <issuerAddress>
                <ns2:street1>117 Kendrick St, Suite 450</ns2:street1>
                <ns2:city>Needham</ns2:city>
                <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                <ns2:zipCode>02494</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>6179165445</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>FRANCESCA BARONE</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>32146</noOfUnitsSold>
            <aggregateMarketValue>283849.18</aggregateMarketValue>
            <noOfUnitsOutstanding>47235460</noOfUnitsOutstanding>
            <approxSaleDate>03/18/2025</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/18/2025</acquiredDate>
            <natureOfAcquisitionTransaction>Exercise of Stock Options</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>18000</amountOfSecuritiesAcquired>
            <paymentDate>03/18/2025</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>07/16/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>14146</amountOfSecuritiesAcquired>
            <paymentDate>07/16/2024</paymentDate>
            <natureOfPayment>N/A</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>FRANCESCA BARONE</name>
                <address>
                    <ns2:street1>117 Kendrick St, Suite 450</ns2:street1>
                    <ns2:city>Needham</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02494</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>01/15/2025</saleDate>
            <amountOfSecuritiesSold>13534</amountOfSecuritiesSold>
            <grossProceeds>97783.15</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>FRANCESCA BARONE</name>
                <address>
                    <ns2:street1>117 Kendrick St, Suite 450</ns2:street1>
                    <ns2:city>Needham</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>02494</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>01/08/2025</saleDate>
            <amountOfSecuritiesSold>13673</amountOfSecuritiesSold>
            <grossProceeds>112367.45</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>03/18/2025</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>11/22/2024</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Francesca Barone</signature>
        </noticeSignature>
    </formData>
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144
0001909680
XXXXXXXX
LIVE
0001841387
CANDEL THERAPEUTICS INC
001-40629
117 Kendrick St, Suite 450
Needham
MA
02494
6179165445
FRANCESCA BARONE
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
32146
283849.18
47235460
03/18/2025
NASDAQ
Common
03/18/2025
Exercise of Stock Options
Issuer
N
18000
03/18/2025
Cash
Common
07/16/2024
Restricted Stock Units
Issuer
N
14146
07/16/2024
N/A
N
FRANCESCA BARONE
117 Kendrick St, Suite 450
Needham
MA
02494
Common
01/15/2025
13534
97783.15
FRANCESCA BARONE
117 Kendrick St, Suite 450
Needham
MA
02494
Common
01/08/2025
13673
112367.45
03/18/2025
11/22/2024
/s/ Francesca Barone