<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001894425</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0000914475</issuerCik>
            <issuerName>NEUROCRINE BIOSCIENCES INC</issuerName>
            <secFileNumber>000-22705</secFileNumber>
            <issuerAddress>
                <ns2:street1>6027 Edgewood Bend Court</ns2:street1>
                <ns2:city>San Diego</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>92130</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>8586177600</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>JUDE ONYIA</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>80181</noOfUnitsSold>
            <aggregateMarketValue>10263168.00</aggregateMarketValue>
            <noOfUnitsOutstanding>98965820</noOfUnitsOutstanding>
            <approxSaleDate>07/02/2025</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>07/02/2025</acquiredDate>
            <natureOfAcquisitionTransaction>Exercise of Stock Options</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>80181</amountOfSecuritiesAcquired>
            <paymentDate>07/02/2025</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <remarks>The securities to be sold were and will be received upon the exercise of stock options over the next three months. The dates of acquisition and payment were and will be the dates of exercise/sale.&#13;
</remarks>
        <noticeSignature>
            <noticeDate>07/02/2025</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>11/18/2024</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Jude Onyia</signature>
        </noticeSignature>
    </formData>
</edgarSubmission>
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144
0001894425
XXXXXXXX
LIVE
0000914475
NEUROCRINE BIOSCIENCES INC
000-22705
6027 Edgewood Bend Court
San Diego
CA
92130
8586177600
JUDE ONYIA
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
80181
10263168.00
98965820
07/02/2025
NASDAQ
Common
07/02/2025
Exercise of Stock Options
Issuer
N
80181
07/02/2025
Cash
Y
The securities to be sold were and will be received upon the exercise of stock options over the next three months. The dates of acquisition and payment were and will be the dates of exercise/sale.
07/02/2025
11/18/2024
/s/ Jude Onyia