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                    <ccc>XXXXXXXX</ccc>
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            <liveTestFlag>LIVE</liveTestFlag>



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            <issuerCik>0001756262</issuerCik>
            <issuerName>TRANSMEDICS GROUP, INC.</issuerName>
            <secFileNumber>001-38891</secFileNumber>
            <issuerAddress>
                <ns2:street1>200 Minuteman Road</ns2:street1>
                <ns2:city>Andover</ns2:city>
                <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                <ns2:zipCode>01810</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>(978) 552-0900</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>EDWARD BASILE</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Director</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>6750</noOfUnitsSold>
            <aggregateMarketValue>1012225.28</aggregateMarketValue>
            <noOfUnitsOutstanding>33359363</noOfUnitsOutstanding>
            <approxSaleDate>08/06/2024</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>08/06/2024</acquiredDate>
            <natureOfAcquisitionTransaction>Stock Option Exercise</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>6750</amountOfSecuritiesAcquired>
            <paymentDate>08/06/2024</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>EDWARD BASILE</name>
                <address>
                    <ns2:street1>200 Minuteman Road</ns2:street1>
                    <ns2:city>Andover</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>01810</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>COMMON</securitiesClassTitle>
            <saleDate>06/05/2024</saleDate>
            <amountOfSecuritiesSold>1193</amountOfSecuritiesSold>
            <grossProceeds>164723.48</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>EDWARD BASILE</name>
                <address>
                    <ns2:street1>200 Minuteman Road</ns2:street1>
                    <ns2:city>Andover</ns2:city>
                    <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                    <ns2:zipCode>01810</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>05/07/2024</saleDate>
            <amountOfSecuritiesSold>7157</amountOfSecuritiesSold>
            <grossProceeds>930295.49</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>08/06/2024</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>09/06/2023</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Edward Michael Basile</signature>
        </noticeSignature>
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144
0001773661
XXXXXXXX
LIVE
0001756262
TRANSMEDICS GROUP, INC.
001-38891
200 Minuteman Road
Andover
MA
01810
(978) 552-0900
EDWARD BASILE
Director
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
6750
1012225.28
33359363
08/06/2024
NASDAQ
Common
08/06/2024
Stock Option Exercise
Issuer
N
6750
08/06/2024
Cash
N
EDWARD BASILE
200 Minuteman Road
Andover
MA
01810
COMMON
06/05/2024
1193
164723.48
EDWARD BASILE
200 Minuteman Road
Andover
MA
01810
Common
05/07/2024
7157
930295.49
08/06/2024
09/06/2023
/s/ Edward Michael Basile