<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001208563</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001585364</issuerCik>
            <issuerName>PERRIGO COMPANY PUBLIC LIMITED COMPANY</issuerName>
            <secFileNumber>001-36353</secFileNumber>
            <issuerAddress>
                <ns2:street1>The Sharp Building, Hogan Place</ns2:street1>
                <ns2:city>Dublin 2</ns2:city>
                <ns2:stateOrCountry>L2</ns2:stateOrCountry>
                <ns2:zipCode>D02 TY74</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>(353) 1-709-4002</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>MURRAY S. KESSLER</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
                <relationshipToIssuer>Director</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>38th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>197646</noOfUnitsSold>
            <aggregateMarketValue>7066358.38</aggregateMarketValue>
            <noOfUnitsOutstanding>135325847</noOfUnitsOutstanding>
            <approxSaleDate>05/11/2023</approxSaleDate>
            <securitiesExchangeName>NYSE</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/05/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units vested under an S-8 Issuer Registered Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>8857</amountOfSecuritiesAcquired>
            <paymentDate>03/05/2023</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/07/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units vested under an S-8 Issuer Registered Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>12476</amountOfSecuritiesAcquired>
            <paymentDate>03/07/2023</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/05/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units vested under an S-8 Issuer Registered Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>11896</amountOfSecuritiesAcquired>
            <paymentDate>03/05/2023</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/03/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units vested under an S-8 Issuer Registered Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>43916</amountOfSecuritiesAcquired>
            <paymentDate>03/03/2023</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/06/2022</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units vested under an S-8 Issuer Registered Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>10321</amountOfSecuritiesAcquired>
            <paymentDate>03/06/2022</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/05/2022</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units vested under an S-8 Issuer Registered Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>11896</amountOfSecuritiesAcquired>
            <paymentDate>03/05/2022</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/05/2022</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units vested under an S-8 Issuer Registered Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>8857</amountOfSecuritiesAcquired>
            <paymentDate>03/05/2022</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/04/2022</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units vested under an S-8 Issuer Registered Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>45945</amountOfSecuritiesAcquired>
            <paymentDate>03/04/2022</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/06/2021</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units vested under an S-8 Issuer Registered Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>9763</amountOfSecuritiesAcquired>
            <paymentDate>03/06/2021</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/05/2021</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units vested under an S-8 Issuer Registered Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>8378</amountOfSecuritiesAcquired>
            <paymentDate>03/05/2021</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>03/06/2020</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units vested under an S-8 Issuer Registered Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>9658</amountOfSecuritiesAcquired>
            <paymentDate>03/06/2020</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>11/09/2018</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units vested under an S-8 Issuer Registered Plan</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>15683</amountOfSecuritiesAcquired>
            <paymentDate>11/09/2018</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>05/11/2023</noticeDate>
            <planAdoptionDates/>
            <signature>/s/ Murray S Kessler</signature>
        </noticeSignature>
    </formData>
</edgarSubmission>
[{"type": "144", "sequence": "1", "filename": "primary_doc.xml", "secsgml_size_bytes": 10386}]
144
0001208563
XXXXXXXX
LIVE
0001585364
PERRIGO COMPANY PUBLIC LIMITED COMPANY
001-36353
The Sharp Building, Hogan Place
Dublin 2
L2
D02 TY74
(353) 1-709-4002
MURRAY S. KESSLER
Officer
Director
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
38th Floor
New York
NY
10004
197646
7066358.38
135325847
05/11/2023
NYSE
Common
03/05/2023
Restricted Stock Units vested under an S-8 Issuer Registered Plan
Issuer
N
8857
03/05/2023
Not Applicable
Common
03/07/2023
Restricted Stock Units vested under an S-8 Issuer Registered Plan
Issuer
N
12476
03/07/2023
Not Applicable
Common
03/05/2023
Restricted Stock Units vested under an S-8 Issuer Registered Plan
Issuer
N
11896
03/05/2023
Not Applicable
Common
03/03/2023
Restricted Stock Units vested under an S-8 Issuer Registered Plan
Issuer
N
43916
03/03/2023
Not Applicable
Common
03/06/2022
Restricted Stock Units vested under an S-8 Issuer Registered Plan
Issuer
N
10321
03/06/2022
Not Applicable
Common
03/05/2022
Restricted Stock Units vested under an S-8 Issuer Registered Plan
Issuer
N
11896
03/05/2022
Not Applicable
Common
03/05/2022
Restricted Stock Units vested under an S-8 Issuer Registered Plan
Issuer
N
8857
03/05/2022
Not Applicable
Common
03/04/2022
Restricted Stock Units vested under an S-8 Issuer Registered Plan
Issuer
N
45945
03/04/2022
Not Applicable
Common
03/06/2021
Restricted Stock Units vested under an S-8 Issuer Registered Plan
Issuer
N
9763
03/06/2021
Not Applicable
Common
03/05/2021
Restricted Stock Units vested under an S-8 Issuer Registered Plan
Issuer
N
8378
03/05/2021
Not Applicable
Common
03/06/2020
Restricted Stock Units vested under an S-8 Issuer Registered Plan
Issuer
N
9658
03/06/2020
Not Applicable
Common
11/09/2018
Restricted Stock Units vested under an S-8 Issuer Registered Plan
Issuer
N
15683
11/09/2018
Not Applicable
Y
05/11/2023
/s/ Murray S Kessler