<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001251368</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0000948708</issuerCik>
            <issuerName>SMITH MICRO SOFTWARE INC.</issuerName>
            <secFileNumber>001-35525</secFileNumber>
            <issuerAddress>
                <ns2:street1>5800 Corporate Drive</ns2:street1>
                <ns2:city>Pittsburgh</ns2:city>
                <ns2:stateOrCountry>PA</ns2:stateOrCountry>
                <ns2:zipCode>15237</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>(412) 837-5300</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>WILLIAM W SMITH JR</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
                <relationshipToIssuer>Director</relationshipToIssuer>
                <relationshipToIssuer>10% Stockholder</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>7066</noOfUnitsSold>
            <aggregateMarketValue>5512.19</aggregateMarketValue>
            <noOfUnitsOutstanding>17736708</noOfUnitsOutstanding>
            <approxSaleDate>12/03/2024</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>04/16/2011</acquiredDate>
            <natureOfAcquisitionTransaction>Compensation</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>7066</amountOfSecuritiesAcquired>
            <paymentDate>04/16/2011</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <remarks>All securities are to be sold by the Smith Living Trust. Securities to be sold for tax planning purposes</remarks>
        <noticeSignature>
            <noticeDate>12/03/2024</noticeDate>
            <planAdoptionDates/>
            <signature>/s/ William W Smith, Jr</signature>
        </noticeSignature>
    </formData>
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144
0001251368
XXXXXXXX
LIVE
0000948708
SMITH MICRO SOFTWARE INC.
001-35525
5800 Corporate Drive
Pittsburgh
PA
15237
(412) 837-5300
WILLIAM W SMITH JR
Officer
Director
10% Stockholder
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
7066
5512.19
17736708
12/03/2024
NASDAQ
Common
04/16/2011
Compensation
Issuer
N
7066
04/16/2011
Not Applicable
Y
All securities are to be sold by the Smith Living Trust. Securities to be sold for tax planning purposes
12/03/2024
/s/ William W Smith, Jr