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    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0002019194</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0001627475</issuerCik>
            <issuerName>UPWORK INC.</issuerName>
            <secFileNumber>001-38678</secFileNumber>
            <issuerAddress>
                <ns2:street1>530 Lytton Avenue,</ns2:street1>
                <ns2:street2>Suite 301</ns2:street2>
                <ns2:city>Palo Alto</ns2:city>
                <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                <ns2:zipCode>94301</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>(650) 316-7500</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>DAVID BOTTOMS</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>11562</noOfUnitsSold>
            <aggregateMarketValue>156148.28</aggregateMarketValue>
            <noOfUnitsOutstanding>131589909</noOfUnitsOutstanding>
            <approxSaleDate>06/18/2025</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>06/18/2025</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>11562</amountOfSecuritiesAcquired>
            <paymentDate>06/18/2025</paymentDate>
            <natureOfPayment>Not Applicable</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>DAVID BOTTOMS</name>
                <address>
                    <ns2:street1>530 Lytton Avenue,</ns2:street1>
                    <ns2:street2>Suite 301</ns2:street2>
                    <ns2:city>Palo Alto</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94301</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>05/20/2025</saleDate>
            <amountOfSecuritiesSold>1620</amountOfSecuritiesSold>
            <grossProceeds>26583.39</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>DAVID BOTTOMS</name>
                <address>
                    <ns2:street1>530 Lytton Avenue,</ns2:street1>
                    <ns2:street2>Suite 301</ns2:street2>
                    <ns2:city>Palo Alto</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94301</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>05/19/2025</saleDate>
            <amountOfSecuritiesSold>2130</amountOfSecuritiesSold>
            <grossProceeds>35602.31</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>DAVID BOTTOM</name>
                <address>
                    <ns2:street1>530 Lytton Avenue,</ns2:street1>
                    <ns2:street2>Suite 301</ns2:street2>
                    <ns2:city>Palo Alto</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94301</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>05/15/2025</saleDate>
            <amountOfSecuritiesSold>1009</amountOfSecuritiesSold>
            <grossProceeds>17294.87</grossProceeds>
        </securitiesSoldInPast3Months>
        <securitiesSoldInPast3Months>
            <sellerDetails>
                <name>DAVID BOTTOMS</name>
                <address>
                    <ns2:street1>530 Lytton Avenue,</ns2:street1>
                    <ns2:street2>Suite 301</ns2:street2>
                    <ns2:city>Palo Alto</ns2:city>
                    <ns2:stateOrCountry>CA</ns2:stateOrCountry>
                    <ns2:zipCode>94301</ns2:zipCode>
                </address>
            </sellerDetails>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <saleDate>03/19/2025</saleDate>
            <amountOfSecuritiesSold>9593</amountOfSecuritiesSold>
            <grossProceeds>129133.15</grossProceeds>
        </securitiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>06/18/2025</noticeDate>
            <planAdoptionDates/>
            <signature>/s/ David Bottoms</signature>
        </noticeSignature>
    </formData>
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144
0002019194
XXXXXXXX
LIVE
0001627475
UPWORK INC.
001-38678
530 Lytton Avenue,
Suite 301
Palo Alto
CA
94301
(650) 316-7500
DAVID BOTTOMS
Officer
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
8th Floor
New York
NY
10004
11562
156148.28
131589909
06/18/2025
NASDAQ
Common
06/18/2025
Restricted Stock
Issuer
N
11562
06/18/2025
Not Applicable
N
DAVID BOTTOMS
530 Lytton Avenue,
Suite 301
Palo Alto
CA
94301
Common
05/20/2025
1620
26583.39
DAVID BOTTOMS
530 Lytton Avenue,
Suite 301
Palo Alto
CA
94301
Common
05/19/2025
2130
35602.31
DAVID BOTTOM
530 Lytton Avenue,
Suite 301
Palo Alto
CA
94301
Common
05/15/2025
1009
17294.87
DAVID BOTTOMS
530 Lytton Avenue,
Suite 301
Palo Alto
CA
94301
Common
03/19/2025
9593
129133.15
06/18/2025
/s/ David Bottoms