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        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001197735</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0000885725</issuerCik>
            <issuerName>BOSTON SCIENTIFIC CORPORATION</issuerName>
            <secFileNumber>001-11083</secFileNumber>
            <issuerAddress>
                <ns2:street1>300 BOSTON SCIENTIFIC WAY</ns2:street1>
                <ns2:city>MARLBOROUGH</ns2:city>
                <ns2:stateOrCountry>MA</ns2:stateOrCountry>
                <ns2:zipCode>01752</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>(508) 683-4000</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>THE DONNA A JAMES FAMILY TRUST</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Former Director</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>38th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>30003</noOfUnitsSold>
            <aggregateMarketValue>1602482.17</aggregateMarketValue>
            <noOfUnitsOutstanding>1437698101</noOfUnitsOutstanding>
            <approxSaleDate>05/23/2023</approxSaleDate>
            <securitiesExchangeName>NYSE</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>05/03/2016</acquiredDate>
            <natureOfAcquisitionTransaction>Annual Equity Award</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>8758</amountOfSecuritiesAcquired>
            <paymentDate>05/03/2016</paymentDate>
            <natureOfPayment>Services Rendered</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>05/10/2018</acquiredDate>
            <natureOfAcquisitionTransaction>Annual Equity Award</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>6109</amountOfSecuritiesAcquired>
            <paymentDate>05/10/2018</paymentDate>
            <natureOfPayment>Services Rendered</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>05/09/2017</acquiredDate>
            <natureOfAcquisitionTransaction>Annual Equity Award</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>7012</amountOfSecuritiesAcquired>
            <paymentDate>05/09/2017</paymentDate>
            <natureOfPayment>Services Rendered</natureOfPayment>
        </securitiesToBeSold>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>05/06/2023</acquiredDate>
            <natureOfAcquisitionTransaction>Annual Equity Award</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>8124</amountOfSecuritiesAcquired>
            <paymentDate>05/06/2023</paymentDate>
            <natureOfPayment>Services Rendered</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <noticeSignature>
            <noticeDate>05/23/2023</noticeDate>
            <planAdoptionDates/>
            <signature>/s/ Donna James, Trustee</signature>
        </noticeSignature>
    </formData>
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144
0001197735
XXXXXXXX
LIVE
0000885725
BOSTON SCIENTIFIC CORPORATION
001-11083
300 BOSTON SCIENTIFIC WAY
MARLBOROUGH
MA
01752
(508) 683-4000
THE DONNA A JAMES FAMILY TRUST
Former Director
Common
Morgan Stanley Smith Barney LLC Executive Financial Services
1 New York Plaza
38th Floor
New York
NY
10004
30003
1602482.17
1437698101
05/23/2023
NYSE
Common
05/03/2016
Annual Equity Award
Issuer
N
8758
05/03/2016
Services Rendered
Common
05/10/2018
Annual Equity Award
Issuer
N
6109
05/10/2018
Services Rendered
Common
05/09/2017
Annual Equity Award
Issuer
N
7012
05/09/2017
Services Rendered
Common
05/06/2023
Annual Equity Award
Issuer
N
8124
05/06/2023
Services Rendered
Y
05/23/2023
/s/ Donna James, Trustee