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<title>vrtx-20200918</title></head><body><div style="display:none"><ix:header><ix:hidden><ix:nonNumeric contextRef="ib85c21278a4f4c849c94f12ded7a51fb_D20200918-20200918" name="dei:EntityCentralIndexKey" id="id3VybDovL2RvY3MudjEvZG9jOjhkZDUxODA4YjEyODQ5NDU4ZDcxOWM4NGJjZjFlYWM2L3NlYzo4ZGQ1MTgwOGIxMjg0OTQ1OGQ3MTljODRiY2YxZWFjNl8xMy9mcmFnOmMwMjE0MjE1NjJhZDQzNTViYTdlZDMzNDI3ZjgwMDM2L3RhYmxlOjJkMTE4Yzk1ODAwMzRmMWM4YmYyNmIzNTZjODEzN2E0L3RhYmxlcmFuZ2U6MmQxMThjOTU4MDAzNGYxYzhiZjI2YjM1NmM4MTM3YTRfMi0xLTEtMS0w_ce539b22-21b7-4a1f-9fb3-20e15a4c98ac">0000875320</ix:nonNumeric><ix:nonNumeric contextRef="ib85c21278a4f4c849c94f12ded7a51fb_D20200918-20200918" name="dei:EntityRegistrantName" id="id3VybDovL2RvY3MudjEvZG9jOjhkZDUxODA4YjEyODQ5NDU4ZDcxOWM4NGJjZjFlYWM2L3NlYzo4ZGQ1MTgwOGIxMjg0OTQ1OGQ3MTljODRiY2YxZWFjNl8xMy9mcmFnOmMwMjE0MjE1NjJhZDQzNTViYTdlZDMzNDI3ZjgwMDM2L3RhYmxlOjJkMTE4Yzk1ODAwMzRmMWM4YmYyNmIzNTZjODEzN2E0L3RhYmxlcmFuZ2U6MmQxMThjOTU4MDAzNGYxYzhiZjI2YjM1NmM4MTM3YTRfMy0xLTEtMS0w_c5b5bf50-561d-44f3-ade4-fb7ddc2062b3">VERTEX PHARMACEUTICALS INC / MA</ix:nonNumeric><ix:nonNumeric contextRef="ib85c21278a4f4c849c94f12ded7a51fb_D20200918-20200918" name="dei:AmendmentFlag" id="id3VybDovL2RvY3MudjEvZG9jOjhkZDUxODA4YjEyODQ5NDU4ZDcxOWM4NGJjZjFlYWM2L3NlYzo4ZGQ1MTgwOGIxMjg0OTQ1OGQ3MTljODRiY2YxZWFjNl8xMy9mcmFnOmMwMjE0MjE1NjJhZDQzNTViYTdlZDMzNDI3ZjgwMDM2L3RhYmxlOjJkMTE4Yzk1ODAwMzRmMWM4YmYyNmIzNTZjODEzN2E0L3RhYmxlcmFuZ2U6MmQxMThjOTU4MDAzNGYxYzhiZjI2YjM1NmM4MTM3YTRfNi0xLTEtMS0w_5bfff962-6394-4f0b-a4a9-298682bb3c1f">false</ix:nonNumeric></ix:hidden><ix:references xml:lang="en-US"><link:schemaRef xlink:type="simple" xlink:href="vrtx-20200918.xsd"></link:schemaRef></ix:references><ix:resources><xbrli:context id="ib85c21278a4f4c849c94f12ded7a51fb_D20200918-20200918"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000875320</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:startDate>2020-09-18</xbrli:startDate><xbrli:endDate>2020-09-18</xbrli:endDate></xbrli:period></xbrli:context></ix:resources></ix:header></div><div id="i8dd51808b12849458d719c84bcf1eac6_1"></div><div style="min-height:42.75pt;width:100%;"><div><span><br/></span></div></div><div style="text-align:center;margin-bottom:6pt;"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:100.000%;"><tr><td style="width:1.0%;"></td><td style="width:98.900%;"></td><td style="width:0.1%;"></td></tr><tr><td colspan="3" style="height:5pt;background-color:rgb(255,255,255, 0.0);text-align:left;vertical-align:bottom;border-bottom:2pt solid #000000;padding-left:1pt;padding-right:1pt;"></td></tr></table></div><div style="text-align:center;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:700;line-height:120%;">UNITED STATES</span></div><div style="text-align:center;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:700;line-height:120%;">SECURITIES AND EXCHANGE COMMISSION</span></div><div style="text-align:center;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:700;line-height:232%;">Washington, D.C. 20549</span></div><div style="text-align:center;margin-bottom:18pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:14pt;font-weight:700;line-height:232%;">FORM <ix:nonNumeric contextRef="ib85c21278a4f4c849c94f12ded7a51fb_D20200918-20200918" name="dei:DocumentType" id="id3VybDovL2RvY3MudjEvZG9jOjhkZDUxODA4YjEyODQ5NDU4ZDcxOWM4NGJjZjFlYWM2L3NlYzo4ZGQ1MTgwOGIxMjg0OTQ1OGQ3MTljODRiY2YxZWFjNl8xL2ZyYWc6NzdjZDA3YTJlZjE1NGNmNThjMjFmNGUwMjdiNGY5NmYvdGV4dHJlZ2lvbjo3N2NkMDdhMmVmMTU0Y2Y1OGMyMWY0ZTAyN2I0Zjk2Zl8xNjMw_1625d1f3-8877-43f3-a657-b957052d0e8c">8-K</ix:nonNumeric> </span></div><div style="text-align:center;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:700;line-height:120%;">CURRENT REPORT</span></div><div style="text-align:center;margin-top:1pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#231f20;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:700;line-height:120%;">Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934</span></div><div style="text-align:center;"><span><br/></span></div><div style="text-align:center;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%;">Date of Report (Date of earliest event reported) <ix:nonNumeric contextRef="ib85c21278a4f4c849c94f12ded7a51fb_D20200918-20200918" format="ixt:datemonthdayyearen" name="dei:DocumentPeriodEndDate" id="id3VybDovL2RvY3MudjEvZG9jOjhkZDUxODA4YjEyODQ5NDU4ZDcxOWM4NGJjZjFlYWM2L3NlYzo4ZGQ1MTgwOGIxMjg0OTQ1OGQ3MTljODRiY2YxZWFjNl8xL2ZyYWc6NzdjZDA3YTJlZjE1NGNmNThjMjFmNGUwMjdiNGY5NmYvdGV4dHJlZ2lvbjo3N2NkMDdhMmVmMTU0Y2Y1OGMyMWY0ZTAyN2I0Zjk2Zl8yMjY_17bedc60-9671-465f-81b6-8a974e1e5f7a">September 18, 2020</ix:nonNumeric> </span></div><div><span><br/></span></div><div style="text-align:center;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:16pt;font-weight:700;line-height:144%;">Vertex Pharmaceuticals Incorporated </span></div><div style="text-align:center;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:9pt;font-weight:400;line-height:144%;">(Exact name of registrant as specified in its charter)</span></div><div style="text-align:center;margin-bottom:6pt;"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:100.000%;"><tr><td style="width:1.0%;"></td><td style="width:32.233%;"></td><td style="width:0.1%;"></td><td style="width:1.0%;"></td><td style="width:32.233%;"></td><td style="width:0.1%;"></td><td style="width:1.0%;"></td><td style="width:32.234%;"></td><td style="width:0.1%;"></td></tr><tr><td colspan="3" style="padding-top:2px;padding-bottom:2px;background-color:rgb(255,255,255, 0.0);text-align:left;vertical-align:bottom;padding-left:1pt;padding-right:1pt;"><div style="padding-left:2.25pt;padding-right:2.25pt;text-align:center;margin-bottom:1pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New 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0.0);text-align:left;vertical-align:top;padding-left:1pt;padding-right:1pt;"><div style="padding-right:2.25pt;text-align:center;margin-bottom:1pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:9pt;font-style:italic;font-weight:400;line-height:100%;">(Commission File Number)</span></div></td><td colspan="3" style="padding-top:2px;padding-bottom:2px;background-color:rgb(255,255,255, 0.0);text-align:left;vertical-align:top;padding-left:1pt;padding-right:1pt;"><div style="padding-left:2.25pt;padding-right:2.25pt;text-align:center;margin-bottom:1pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:9pt;font-style:italic;font-weight:400;line-height:100%;">(I.R.S. Employer Identification No.)</span></div></td></tr></table></div><div style="text-align:center;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:144%;"><ix:nonNumeric contextRef="ib85c21278a4f4c849c94f12ded7a51fb_D20200918-20200918" name="dei:EntityAddressAddressLine1" id="id3VybDovL2RvY3MudjEvZG9jOjhkZDUxODA4YjEyODQ5NDU4ZDcxOWM4NGJjZjFlYWM2L3NlYzo4ZGQ1MTgwOGIxMjg0OTQ1OGQ3MTljODRiY2YxZWFjNl8xL2ZyYWc6NzdjZDA3YTJlZjE1NGNmNThjMjFmNGUwMjdiNGY5NmYvdGV4dHJlZ2lvbjo3N2NkMDdhMmVmMTU0Y2Y1OGMyMWY0ZTAyN2I0Zjk2Zl8xNjI0_3bb1494b-98ae-4c70-8739-ab071b187dee">50 Northern Avenue</ix:nonNumeric> </span></div><div style="text-align:center;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:144%;"><ix:nonNumeric contextRef="ib85c21278a4f4c849c94f12ded7a51fb_D20200918-20200918" name="dei:EntityAddressCityOrTown" id="id3VybDovL2RvY3MudjEvZG9jOjhkZDUxODA4YjEyODQ5NDU4ZDcxOWM4NGJjZjFlYWM2L3NlYzo4ZGQ1MTgwOGIxMjg0OTQ1OGQ3MTljODRiY2YxZWFjNl8xL2ZyYWc6NzdjZDA3YTJlZjE1NGNmNThjMjFmNGUwMjdiNGY5NmYvdGV4dHJlZ2lvbjo3N2NkMDdhMmVmMTU0Y2Y1OGMyMWY0ZTAyN2I0Zjk2Zl8xNjI1_44c0c058-4273-4f5c-8000-6fd383c26459">Boston</ix:nonNumeric>, <ix:nonNumeric contextRef="ib85c21278a4f4c849c94f12ded7a51fb_D20200918-20200918" format="ixt-sec:stateprovnameen" name="dei:EntityAddressStateOrProvince" id="id3VybDovL2RvY3MudjEvZG9jOjhkZDUxODA4YjEyODQ5NDU4ZDcxOWM4NGJjZjFlYWM2L3NlYzo4ZGQ1MTgwOGIxMjg0OTQ1OGQ3MTljODRiY2YxZWFjNl8xL2ZyYWc6NzdjZDA3YTJlZjE1NGNmNThjMjFmNGUwMjdiNGY5NmYvdGV4dHJlZ2lvbjo3N2NkMDdhMmVmMTU0Y2Y1OGMyMWY0ZTAyN2I0Zjk2Zl8xNjI2_ed6d9cd2-ed8e-4d15-9a39-6d9f96b94526">Massachusetts</ix:nonNumeric>  <ix:nonNumeric contextRef="ib85c21278a4f4c849c94f12ded7a51fb_D20200918-20200918" name="dei:EntityAddressPostalZipCode" id="id3VybDovL2RvY3MudjEvZG9jOjhkZDUxODA4YjEyODQ5NDU4ZDcxOWM4NGJjZjFlYWM2L3NlYzo4ZGQ1MTgwOGIxMjg0OTQ1OGQ3MTljODRiY2YxZWFjNl8xL2ZyYWc6NzdjZDA3YTJlZjE1NGNmNThjMjFmNGUwMjdiNGY5NmYvdGV4dHJlZ2lvbjo3N2NkMDdhMmVmMTU0Y2Y1OGMyMWY0ZTAyN2I0Zjk2Zl8xNjI3_9eabefe4-5458-4010-b056-fb7f200c32a5">02210</ix:nonNumeric> </span></div><div style="text-align:center;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:9pt;font-style:italic;font-weight:400;line-height:144%;">(Address of principal executive offices) (Zip Code)</span></div><div style="text-align:center;"><span><br/></span></div><div style="text-align:center;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:144%;">(<ix:nonNumeric contextRef="ib85c21278a4f4c849c94f12ded7a51fb_D20200918-20200918" name="dei:CityAreaCode" id="id3VybDovL2RvY3MudjEvZG9jOjhkZDUxODA4YjEyODQ5NDU4ZDcxOWM4NGJjZjFlYWM2L3NlYzo4ZGQ1MTgwOGIxMjg0OTQ1OGQ3MTljODRiY2YxZWFjNl8xL2ZyYWc6NzdjZDA3YTJlZjE1NGNmNThjMjFmNGUwMjdiNGY5NmYvdGV4dHJlZ2lvbjo3N2NkMDdhMmVmMTU0Y2Y1OGMyMWY0ZTAyN2I0Zjk2Zl8xNjMx_a983ff00-ea24-40a9-99c5-531c023485e8">617</ix:nonNumeric>) <ix:nonNumeric contextRef="ib85c21278a4f4c849c94f12ded7a51fb_D20200918-20200918" name="dei:LocalPhoneNumber" id="id3VybDovL2RvY3MudjEvZG9jOjhkZDUxODA4YjEyODQ5NDU4ZDcxOWM4NGJjZjFlYWM2L3NlYzo4ZGQ1MTgwOGIxMjg0OTQ1OGQ3MTljODRiY2YxZWFjNl8xL2ZyYWc6NzdjZDA3YTJlZjE1NGNmNThjMjFmNGUwMjdiNGY5NmYvdGV4dHJlZ2lvbjo3N2NkMDdhMmVmMTU0Y2Y1OGMyMWY0ZTAyN2I0Zjk2Zl8xNjMy_2db1aefd-d039-43f0-8a36-d98e2bab2fb5">341-6100</ix:nonNumeric> </span></div><div style="text-align:center;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:110%;">(Registrant's telephone number, including area code)</span></div><div style="padding-left:11.25pt;text-align:center;"><span><br/></span></div><div><span><br/></span></div><div><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:9pt;font-weight:400;line-height:120%;">Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):</span></div><div><span><br/></span></div><div style="padding-left:2.25pt;padding-right:2.25pt;margin-bottom:1pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:9pt;font-weight:400;line-height:174%;"><ix:nonNumeric contextRef="ib85c21278a4f4c849c94f12ded7a51fb_D20200918-20200918" format="ixt-sec:boolballotbox" name="dei:WrittenCommunications" 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Roman',sans-serif;font-size:9pt;font-weight:400;line-height:174%;">Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) </span></div><div style="text-align:center;margin-bottom:6pt;"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:99.853%;"><tr><td style="width:1.0%;"></td><td style="width:33.453%;"></td><td style="width:0.1%;"></td><td style="width:1.0%;"></td><td style="width:2.853%;"></td><td style="width:0.1%;"></td><td style="width:1.0%;"></td><td style="width:17.640%;"></td><td style="width:0.1%;"></td><td style="width:1.0%;"></td><td style="width:2.853%;"></td><td style="width:0.1%;"></td><td style="width:1.0%;"></td><td style="width:37.701%;"></td><td style="width:0.1%;"></td></tr><tr><td colspan="15" style="padding-top:2px;padding-bottom:2px;background-color:rgb(255,255,255, 0.0);text-align:left;vertical-align:bottom;padding-left:1pt;padding-right:1pt;"><div style="padding-left:2.25pt;padding-right:58.5pt;margin-bottom:2pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:9pt;font-weight:400;line-height:100%;">Securities registered pursuant to Section 12(b) of the Act:</span></div></td><td colspan="3" style="display:none;"></td><td colspan="3" style="display:none;"></td><td colspan="3" style="display:none;"></td><td colspan="3" style="display:none;"></td></tr><tr><td colspan="3" style="padding-top:2px;padding-bottom:2px;background-color:rgb(255,255,255, 0.0);text-align:left;vertical-align:bottom;padding-left:1pt;padding-right:1pt;"><div style="padding-left:2.25pt;padding-right:2.25pt;text-align:center;margin-bottom:2pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:9pt;font-weight:400;line-height:100%;">Title of each class</span></div></td><td colspan="3" style="background-color:rgb(255,255,255, 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id="id3VybDovL2RvY3MudjEvZG9jOjhkZDUxODA4YjEyODQ5NDU4ZDcxOWM4NGJjZjFlYWM2L3NlYzo4ZGQ1MTgwOGIxMjg0OTQ1OGQ3MTljODRiY2YxZWFjNl8xL2ZyYWc6NzdjZDA3YTJlZjE1NGNmNThjMjFmNGUwMjdiNGY5NmYvdGFibGU6ZGY0YTdkYmYyZDgxNGQwYTlkMjYxODhkNTVkNjk2YmIvdGFibGVyYW5nZTpkZjRhN2RiZjJkODE0ZDBhOWQyNjE4OGQ1NWQ2OTZiYl8yLTAtMS0xLTA_28d16f8e-ecc6-4b2e-87ca-8167fd0edb9e">Common Stock, $0.01 Par Value Per Share</ix:nonNumeric></span></div></td><td colspan="3" style="background-color:rgb(255,255,255, 0.0);text-align:left;vertical-align:bottom;padding-left:1pt;padding-right:1pt;"></td><td colspan="3" style="padding-top:2px;padding-bottom:2px;background-color:rgb(255,255,255, 0.0);text-align:left;vertical-align:middle;border-top:1pt solid #000000;padding-left:1pt;padding-right:1pt;"><div style="padding-left:2.25pt;padding-right:2.25pt;text-align:center;margin-bottom:2pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New 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style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:9pt;font-weight:400;line-height:100%;"><ix:nonNumeric contextRef="ib85c21278a4f4c849c94f12ded7a51fb_D20200918-20200918" format="ixt-sec:exchnameen" name="dei:SecurityExchangeName" id="id3VybDovL2RvY3MudjEvZG9jOjhkZDUxODA4YjEyODQ5NDU4ZDcxOWM4NGJjZjFlYWM2L3NlYzo4ZGQ1MTgwOGIxMjg0OTQ1OGQ3MTljODRiY2YxZWFjNl8xL2ZyYWc6NzdjZDA3YTJlZjE1NGNmNThjMjFmNGUwMjdiNGY5NmYvdGFibGU6ZGY0YTdkYmYyZDgxNGQwYTlkMjYxODhkNTVkNjk2YmIvdGFibGVyYW5nZTpkZjRhN2RiZjJkODE0ZDBhOWQyNjE4OGQ1NWQ2OTZiYl8yLTQtMS0xLTA_43703ae1-a31c-43cf-adfd-295e21cb0eac">The Nasdaq Global Select Market</ix:nonNumeric></span></div></td></tr></table></div><div><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:9pt;font-weight:400;line-height:120%;">Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (&#167;230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (&#167;240.12b-2 of this chapter).</span></div><div><span><br/></span></div><div><span style="background-color:rgb(255,255,255, 0.0);color:#231f20;font-family:'Times New Roman',sans-serif;font-size:9pt;font-weight:400;line-height:120%;">Emerging growth company </span><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:9pt;font-weight:400;line-height:120%;"><ix:nonNumeric contextRef="ib85c21278a4f4c849c94f12ded7a51fb_D20200918-20200918" format="ixt-sec:boolballotbox" name="dei:EntityEmergingGrowthCompany" id="id3VybDovL2RvY3MudjEvZG9jOjhkZDUxODA4YjEyODQ5NDU4ZDcxOWM4NGJjZjFlYWM2L3NlYzo4ZGQ1MTgwOGIxMjg0OTQ1OGQ3MTljODRiY2YxZWFjNl8xL2ZyYWc6NzdjZDA3YTJlZjE1NGNmNThjMjFmNGUwMjdiNGY5NmYvdGV4dHJlZ2lvbjo3N2NkMDdhMmVmMTU0Y2Y1OGMyMWY0ZTAyN2I0Zjk2Zl8xNjM0_237f720a-bee7-4cf3-9d09-4c50662cf65c">&#9744;</ix:nonNumeric></span><span style="background-color:rgb(255,255,255, 0.0);color:#231f20;font-family:'Times New Roman',sans-serif;font-size:9pt;font-weight:400;line-height:120%;"> </span></div><div><span><br/></span></div><div><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:9pt;font-weight:400;line-height:120%;">If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. &#9744;</span></div><div style="position:relative;width:100%;height:42.75pt;"><div style="position:absolute;bottom:0;width:100%;"><div><span><br/></span></div></div></div><div id="i8dd51808b12849458d719c84bcf1eac6_4"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%;"><div><span><br/></span></div></div><div><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:700;line-height:144%;">Item 1.01. Entry into a Material Definitive Agreement.</span></div><div style="text-indent:36pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%;">On September 18, 2020, Vertex Pharmaceuticals Incorporated, a Massachusetts corporation (the &#8220;Company&#8221; or &#8220;we&#8221;) entered into a Credit Agreement (the &#8220;Credit Agreement&#8221;), with Vertex Pharmaceuticals (Europe) Limited, a private limited company incorporated in England and Wales and a wholly-owned subsidiary of the Company, as a co-borrower, Vertex Pharmaceuticals (Ireland) Limited, a private company limited by shares incorporated in Ireland and a wholly-owned subsidiary of the Company, as a co-borrower, certain other wholly-owned subsidiaries of the Company as subsidiary guarantors, Bank of America, N.A and the other lenders referred to therein, which is summarized below. The Credit Agreement provides for a $2.0 billion senior unsecured revolving facility. The Credit Agreement also provides that, subject to satisfaction of certain conditions, we may request that the borrowing capacity under the Credit Agreement be increased by an additional $500 million. The Credit Agreement matures on September 18, 2022.</span></div><div style="text-indent:36pt;"><span><br/></span></div><div style="text-indent:36pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%;">Proceeds of borrowings under the Credit Agreement will be used for general corporate purposes. Loans will bear interest, at our option, at either a base rate or a Eurocurrency rate, in each case plus an applicable margin. Under the Credit Agreement, the applicable margin on base rate loans ranges from 0.500% to 0.875% and the applicable margin on Eurocurrency loans ranges from 1.500% to 1.875%, in each case, based on our consolidated leverage ratio (the ratio of our total consolidated funded indebtedness to our consolidated EBITDA for the most recently completed four fiscal quarter period).  Loans under the Credit Agreement may be prepaid at par and commitments under the Credit Agreement may be reduced at any time, in whole or in part, without premium or penalty (except for LIBOR breakage costs).</span></div><div style="text-indent:36pt;"><span><br/></span></div><div style="text-indent:36pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%;">Loans will be guaranteed by certain of our existing and future domestic subsidiaries, subject to certain exceptions.</span></div><div style="text-indent:36pt;"><span><br/></span></div><div style="text-indent:36pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%;">The Credit Agreement contains customary representations and warranties and affirmative and negative covenants, including financial covenants to maintain (x) subject to certain limited exceptions, a consolidated leverage ratio of 3.50 to 1.00, subject to an increase to 4.00 to 1.00 following a material acquisition and (y) a consolidated interest coverage ratio of 2.50 to 1.00, in each case to be measured on a quarterly basis. The Credit Agreement also contains customary events of default. In the case of a continuing event of default, the administrative agent would be entitled to exercise various remedies, including the acceleration of amounts due under any outstanding loan.</span></div><div style="text-indent:36pt;"><span><br/></span></div><div><span><br/></span></div><div><span><br/></span></div><div id="i8dd51808b12849458d719c84bcf1eac6_183"></div><div><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:700;line-height:120%;">Item 2.03. Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant. </span></div><div><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</span></div><div style="text-indent:36pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%;">The information disclosed under Item 1.01 of this Current Report on Form 8-K is incorporated by reference herein.</span></div><div style="text-indent:36pt;"><span><br/></span></div><div style="text-indent:36pt;"><span><br/></span></div><div style="text-indent:36pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%;">The foregoing description of the Credit Agreement does not purport to be complete and is qualified in its entirety by reference to the Credit Agreement, which will be filed with Vertex&#8217;s Quarterly Report on Form 10-Q for the fiscal quarter ended September 30, 2020.</span></div><div style="position:relative;width:100%;height:42.75pt;"><div style="position:absolute;bottom:0;width:100%;"><div><span><br/></span></div></div></div><div id="i8dd51808b12849458d719c84bcf1eac6_10"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%;"><div><span><br/></span></div></div><div style="text-align:center;margin-top:12pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:700;line-height:144%;">SIGNATURES</span></div><div><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:144%;">&#160; </span></div><div style="text-indent:36pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:144%;">Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.</span></div><div><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:144%;">&#160;</span></div><div style="padding-left:2.25pt;margin-bottom:6pt;"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:88.888%;"><tr><td style="width:1.0%;"></td><td style="width:31.794%;"></td><td style="width:0.1%;"></td><td style="width:1.0%;"></td><td style="width:66.006%;"></td><td style="width:0.1%;"></td></tr><tr><td colspan="3" style="background-color:rgb(255,255,255, 0.0);text-align:left;vertical-align:bottom;padding-left:1pt;padding-right:1pt;"></td><td colspan="3" style="padding-top:2px;padding-bottom:2px;background-color:rgb(255,255,255, 0.0);text-align:left;vertical-align:top;padding-left:1pt;padding-right:1pt;"><div style="padding-left:2.25pt;padding-right:2.25pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:700;line-height:100%;">VERTEX PHARMACEUTICALS INCORPORATED</span></div></td></tr><tr><td colspan="3" style="background-color:rgb(255,255,255, 0.0);text-align:left;vertical-align:bottom;padding-left:1pt;padding-right:1pt;"></td><td colspan="3" style="padding-top:2px;padding-bottom:2px;background-color:rgb(255,255,255, 0.0);text-align:left;vertical-align:top;padding-left:1pt;padding-right:1pt;"><div style="padding-left:99pt;padding-right:2.25pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:100%;">(Registrant)</span></div></td></tr><tr><td colspan="3" style="height:15pt;background-color:rgb(255,255,255, 0.0);text-align:left;vertical-align:bottom;padding-left:1pt;padding-right:1pt;"></td><td colspan="3" style="height:15pt;background-color:rgb(255,255,255, 0.0);text-align:left;vertical-align:bottom;padding-left:1pt;padding-right:1pt;"></td></tr><tr><td colspan="3" style="padding-top:2px;padding-bottom:2px;background-color:rgb(255,255,255, 0.0);text-align:left;vertical-align:top;padding-left:1pt;padding-right:1pt;"><span style="font-size:11pt;font-weight:400;font-family:'Times New Roman',sans-serif;color:#000000;background-color:rgb(255,255,255, 0.0);">Date:  September 21, 2020</span></td><td colspan="3" style="padding-top:2px;padding-bottom:2px;background-color:rgb(255,255,255, 0.0);text-align:left;vertical-align:top;padding-left:1pt;padding-right:1pt;"><span style="font-size:11pt;font-weight:400;font-family:'Times New Roman',sans-serif;color:#000000;background-color:rgb(255,255,255, 0.0);">/s/ Michael Parini</span></td></tr><tr><td colspan="3" style="background-color:rgb(255,255,255, 0.0);text-align:left;vertical-align:bottom;padding-left:1pt;padding-right:1pt;"></td><td colspan="3" style="padding-top:2px;padding-bottom:2px;background-color:rgb(255,255,255, 0.0);text-align:left;vertical-align:top;border-top:1pt solid #000000;padding-left:1pt;padding-right:1pt;"><div style="padding-right:2.25pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:100%;">Michael Parini</span></div></td></tr><tr><td colspan="3" style="background-color:rgb(255,255,255, 0.0);text-align:left;vertical-align:bottom;padding-left:1pt;padding-right:1pt;"></td><td colspan="3" style="padding-top:2px;padding-bottom:2px;background-color:rgb(255,255,255, 0.0);text-align:left;vertical-align:bottom;padding-left:1pt;padding-right:1pt;"><div style="padding-right:2.25pt;"><span style="background-color:rgb(255,255,255, 0.0);color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:100%;">Executive Vice President, Chief Administrative, Legal and Business Development Officer</span></div></td></tr></table></div><div style="position:relative;width:100%;height:42.75pt;"><div style="position:absolute;bottom:0;width:100%;"><div><span><br/></span></div></div></div></body></html>
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vrtx-20200918
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM
8-K
CURRENT REPORT
Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934
Date of Report (Date of earliest event reported)
September 18, 2020
Vertex Pharmaceuticals Incorporated
(Exact name of registrant as specified in its charter)
Massachusetts
000-19319
04-3039129
(State or other jurisdiction of incorporation)
(Commission File Number)
(I.R.S. Employer Identification No.)
50 Northern Avenue
Boston
,
Massachusetts
02210
(Address of principal executive offices) (Zip Code)
(
617
)
341-6100
(Registrant's telephone number, including area code)
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):
☐
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
☐
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
☐
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
☐
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Securities registered pursuant to Section 12(b) of the Act:
Title of each class
Trading Symbol
Name of each exchange on which registered
Common Stock, $0.01 Par Value Per Share
VRTX
The Nasdaq Global Select Market
Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).
Emerging growth company
☐
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐
Item 1.01. Entry into a Material Definitive Agreement.
On September 18, 2020, Vertex Pharmaceuticals Incorporated, a Massachusetts corporation (the "Company" or "we") entered into a Credit Agreement (the "Credit Agreement"), with Vertex Pharmaceuticals (Europe) Limited, a private limited company incorporated in England and Wales and a wholly-owned subsidiary of the Company, as a co-borrower, Vertex Pharmaceuticals (Ireland) Limited, a private company limited by shares incorporated in Ireland and a wholly-owned subsidiary of the Company, as a co-borrower, certain other wholly-owned subsidiaries of the Company as subsidiary guarantors, Bank of America, N.A and the other lenders referred to therein, which is summarized below. The Credit Agreement provides for a $2.0 billion senior unsecured revolving facility. The Credit Agreement also provides that, subject to satisfaction of certain conditions, we may request that the borrowing capacity under the Credit Agreement be increased by an additional $500 million. The Credit Agreement matures on September 18, 2022.
Proceeds of borrowings under the Credit Agreement will be used for general corporate purposes. Loans will bear interest, at our option, at either a base rate or a Eurocurrency rate, in each case plus an applicable margin. Under the Credit Agreement, the applicable margin on base rate loans ranges from 0.500% to 0.875% and the applicable margin on Eurocurrency loans ranges from 1.500% to 1.875%, in each case, based on our consolidated leverage ratio (the ratio of our total consolidated funded indebtedness to our consolidated EBITDA for the most recently completed four fiscal quarter period).  Loans under the Credit Agreement may be prepaid at par and commitments under the Credit Agreement may be reduced at any time, in whole or in part, without premium or penalty (except for LIBOR breakage costs).
Loans will be guaranteed by certain of our existing and future domestic subsidiaries, subject to certain exceptions.
The Credit Agreement contains customary representations and warranties and affirmative and negative covenants, including financial covenants to maintain (x) subject to certain limited exceptions, a consolidated leverage ratio of 3.50 to 1.00, subject to an increase to 4.00 to 1.00 following a material acquisition and (y) a consolidated interest coverage ratio of 2.50 to 1.00, in each case to be measured on a quarterly basis. The Credit Agreement also contains customary events of default. In the case of a continuing event of default, the administrative agent would be entitled to exercise various remedies, including the acceleration of amounts due under any outstanding loan.
Item 2.03. Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant.
The information disclosed under Item 1.01 of this Current Report on Form 8-K is incorporated by reference herein.
The foregoing description of the Credit Agreement does not purport to be complete and is qualified in its entirety by reference to the Credit Agreement, which will be filed with Vertex's Quarterly Report on Form 10-Q for the fiscal quarter ended September 30, 2020.
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
VERTEX PHARMACEUTICALS INCORPORATED
(Registrant)
Date:  September 21, 2020
/s/ Michael Parini
Michael Parini
Executive Vice President, Chief Administrative, Legal and Business Development Officer