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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">UNITED
STATES</font></div>
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AND EXCHANGE COMMISSION</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Washington,
D.C.&#160;&#160;20549</font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">FORM
8-K</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">CURRENT
REPORT</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">PURSUANT
TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Date
of Report (Date of earliest event reported) <font style="DISPLAY: inline; TEXT-DECORATION: underline">&#160;&#160;&#160;June 5,
2009</font></font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">APPLIED
NEUROSOLUTIONS, INC.</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(Exact
name of Registrant as Specified in its Charter)</font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><font style="DISPLAY: inline; TEXT-DECORATION: underline">&#160;&#160;Delaware&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;001-13835&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;39-1661164</font></font></div>
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or Other Jurisdiction&#160;&#160;&#160;&#160;&#160;(Commission file
Number)&#160;&#160;&#160;&#160;(IRS Employer</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">&#160;&#160;&#160;&#160;&#160;&#160;&#160;of&#160;&#160;Incorporation)&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;Identification
No.)</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><font style="DISPLAY: inline; TEXT-DECORATION: underline">&#160;&#160;&#160;&#160;50
Lakeview Parkway, Suite 111, Vernon Hills,
IL&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;60061</font></font></div>
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of Principal Executive
Offices)&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;(Zip
Code)</font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Registrant&#8217;s
telephone number, including area code <font style="DISPLAY: inline; TEXT-DECORATION: underline">(847)
573-8000</font></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Check the
appropriate box below if the Form 8-K filing is intended to simultaneously
satisfy the filing obligation of the registrant under any of the following
provisions (see General Instruction A.2. below):</font></div>
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Written communications pursuant to Rule 425 under the Securities Act (17 CFR
230.425)</font></div>
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Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
240.14a-12)</font></div>
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Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act
(17 CFR 240.14d-2(b))</font></div>
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Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act
(17 CFR 240.13e-4(c))</font></div>
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              <div align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: times new roman"><font style="DISPLAY: inline; FONT-WEIGHT: bold">Section 5 &#8211; Corporate
      Governance and Management</font></font></div>
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    </div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Item
5.03.&#160;&#160;Amendments to Articles of Incorporation or Bylaws; Change in
Fiscal Year.</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">On June
5, 2009, the Registrant filed a Certificate of Amendment to its Amended and
Restated Certificate of Incorporation with the Delaware Secretary of State which
serves to effect, as of June 29, 2009, a 1-for-30 reverse split of the
Registrant&#8217;s common stock.&#160;&#160;As a result of the reverse stock split,
every 30 shares of the Registrant&#8217;s common stock will be combined into one share
of common stock, and any fractional shares created by the reverse stock split
will be rounded up to whole shares.&#160;&#160;The reverse stock split affects
all of the Registrant&#8217;s common stock, stock options and warrants outstanding
immediately prior to the effective date of the reverse stock
split.&#160;&#160;The reverse split, which was approved by the Registrant&#8217;s
stockholders at the annual meeting held on September 16, 2008, will reduce the
number of shares of the Registrant&#8217;s common stock outstanding from 130,217,808
shares to approximately 4,342,000 shares, and the number of authorized shares of
common stock will be reduced from 200,000,000 shares to 100,000,000 shares. The
Certificate of Amendment is filed as Exhibit 2.1 hereto.</font></div>
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    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Item
9.01&#160;&#160;Financial Statements and Exhibits.</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(d)&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;Exhibits.</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">2.1&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;Certificate
of Amendment to the Amended and Restated Certificate of Incorporation of Applied
NeuroSolutions, Inc. filed June 5, 2009.</font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">SIGNATURES</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 36pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Pursuant
to the requirements of the Securities Exchange Act of 1934, the registrant has
duly caused this report to be signed on its behalf by the undersigned hereunto
duly authorized on this 10th day of June 2009.</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 216pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">APPLIED
NEUROSOLUTIONS, INC.</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 216pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">By:&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="DISPLAY: inline; TEXT-DECORATION: underline">&#160;&#160;&#160;&#160;/s/&#160;&#160;&#160;&#160;David
Ellison</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 252pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Name:&#160;&#160;David
Ellison</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 252pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Title:&#160;&#160;&#160;&#160;Chief
Financial Officer</font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="right"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">EXHIBIT
2.1</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">CERTIFICATE
OF AMENDMENT</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">OF</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">AMENDED
AND RESTATED CERTIFICATE OF INCORPORATION</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">OF</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">APPLIED
NEUROSOLUTIONS, INC.</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(a
Delaware corporation)</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><font id="TAB1" style="MARGIN-LEFT: 36pt"></font>Applied NeuroSolutions, Inc. (the
&#8220;Corporation&#8221;), a corporation duly organized and existing under the laws of the
State of Delaware, does hereby certify as follows:</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><font id="TAB1" style="MARGIN-LEFT: 36pt"></font>1.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;The
Amended and Restated Certificate of Incorporation of the Corporation is hereby
amended by deleting Article 4 thereof in its entirety and inserting the
following in lieu thereof:</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">ARTICLE
4</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 18pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">4.1&#160;&#160;&#160;&#160;&#160;<font style="DISPLAY: inline; TEXT-DECORATION: underline">Authorized
Stock</font>.</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 18pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">The total
number of shares of all classes of stock that the Corporation shall have
authority to issue is 105,000,000 consisting solely of:</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 72pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">100,000,000
shares of common stock, $.0025 par value per share ("Common Stock");
and</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 72pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">5,000,000
shares of preferred stock, $.0025 par value per share ("Preferred
Stock").</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">The
following is a statement of the powers, designations, preferences, privileges,
and relative, participating, optional, and other special rights of the Preferred
Stock and Common Stock, respectively.</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 18pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">4.2&#160;&#160;&#160;&#160;&#160;&#160;<font style="DISPLAY: inline; TEXT-DECORATION: underline">Preferred
Stock</font>.</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 18pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">The Board
of Directors is hereby expressly authorized to provide for, designate and issue,
out of the authorized but unissued shares of Preferred Stock, one or more series
of Preferred Stock, subject to the terms and conditions set forth
herein.&#160;&#160;Before any shares of any series of Preferred Stock are
issued, the Board of Directors shall fix, and hereby is expressly empowered to
fix, by resolution or resolutions, the following provisions of the shares of any
such series:</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 18pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(a)&#160;&#160;&#160;&#160;&#160;the
designation of such series, the number of shares to constitute such series, and
the stated value thereof if different from the par value;</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 18pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(b)&#160;&#160;&#160;&#160;&#160;whether
the shares of such series shall have voting rights or powers, in addition to any
voting rights required by law, and, if so, the terms of such voting rights or
powers, which may be full or limited;</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 18pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(c)&#160;&#160;&#160;&#160;&#160;the
dividends, if any, payable on such series, whether any such dividends shall be
cumulative, and, if so, from what dates, the conditions and dates upon which
such dividends shall be payable, the preference or relation which such dividends
shall bear to the dividends payable on any shares of stock of any other class or
series;</font></div>
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        </div>
        <div style="WIDTH: 100%; TEXT-ALIGN: center">
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        </div>
      </div>
      <div id="HDR">
        <div id="GLHDR" style="WIDTH: 100%" align="right">
        </div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 18pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(d)&#160;&#160;&#160;&#160;&#160;whether
the shares of such class or series shall be subject to redemption by the
Corporation, and, if so, the times, prices and other conditions of such
redemption;</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 18pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(e)&#160;&#160;&#160;&#160;&#160;the
amount or amounts payable with respect to shares of such class or series upon,
and the rights of the holders of such class or series in, the voluntary or
involuntary liquidations, dissolution or winding up, or upon any distribution of
the assets, of the Corporation;</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 18pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(f)&#160;&#160;&#160;&#160;&#160;whether
the shares of such class or series shall be subject to the operation of a
retirement or sinking fund and, if so, the extent to and manner in which any
such retirement or sinking fund shall be applied to the purchase or redemption
of the shares of such class or series for retirement or other corporate purposes
and the terms and provisions relative to the operation thereof;</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 18pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(g)&#160;&#160;&#160;&#160;&#160;whether
the shares of such class or series shall be convertible into, or exchangeable
for, shares of stock of any other class or series of any other securities and,
if so, the price or prices or the rate or rates of conversion or exchange and
the method, if any, of adjusting the same, and any other terms and conditions of
conversion or exchange;</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 18pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(h)&#160;&#160;&#160;&#160;&#160;the
limitations and restrictions, if any, to be effective while any shares of such
class or series are outstanding upon the payment of dividends or the making of
other distributions on, and upon the purchase, redemption or other acquisition
by the Corporation of, the Common Stock or shares of stock of any other class or
series;</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 18pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(i)&#160;&#160;&#160;&#160;&#160;the
conditions or restrictions, if any, to be effective while any shares of such
class or series are outstanding upon the creation of indebtedness of the
Corporation or upon the issue of any additional stock, including additional
shares of such class or series or of any other class or series; and</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 18pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(j)&#160;&#160;&#160;&#160;&#160;any
other powers, designations, preferences and relative, participating, optional or
other special rights, and any qualifications, limitations or restrictions
thereof.</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 18pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">The
powers, designations, preferences and relative, participating, optional or other
special rights of each series of Preferred Stock, and the qualifications,
limitations or restrictions thereof, if any, may differ from those of any and
all other series at any time outstanding. The Board of Directors is hereby
expressly authorized from time to time to increase (but not above the total
number of authorized shares of Preferred Stock) or decrease (but not below the
number of shares thereof then outstanding) the number of shares of stock of any
series of Preferred Stock designated to any one or more series of Preferred
stock pursuant to this Section 4.2. Different series of Preferred Stock shall
not be construed to constitute different classes of stock for purposes of voting
by classes unless expressly so provided in the resolution or resolutions adopted
by the Board of Directors creating or establishing any such series of Preferred
Stock. No resolution, vote, or consent of the holders of the capital stock of
the Corporation shall be required in connection with the creation or issuance of
any shares of any series of Preferred stock authorized by and complying with the
conditions of this Certificate of Incorporation, the right to any such
resolution, vote, or consent being expressly waived by all present and future
holders of the capital stock of the Corporation.</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div id="PGBRK" style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt">
      <div id="FTR">
        <div id="GLFTR" style="WIDTH: 100%" align="left">
        </div>
      </div>
      <div id="PN" style="PAGE-BREAK-AFTER: always">
        <div style="WIDTH: 100%; TEXT-ALIGN: center">
        </div>
        <div style="WIDTH: 100%; TEXT-ALIGN: center">
          <hr style="COLOR: black" noshade size="2">
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      </div>
      <div id="HDR">
        <div id="GLHDR" style="WIDTH: 100%" align="right">
        </div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 18pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">At such
time as no shares of any series of Preferred Stock that may be issued from time
to time remain issued and outstanding, including without limitation because all
of such shares have been converted into shares of Common Stock in accordance
with this Certificate of Incorporation, all authorized shares of such series of
Preferred Stock, automatically and without further actions, shall be
reclassified as authorized but unissued shares of undesignated Preferred Stock
of no particular class or series, and any and all of such shares may thereafter
be issued by the Board of Directors of the Company in one or more series, and
the terms of any such series may be determined by the Board of Directors, as
provided in this Section 4.2.</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 18pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">4.3&#160;&#160;&#160;&#160;&#160;<font style="DISPLAY: inline; TEXT-DECORATION: underline">Common
Stock</font>.</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 18pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(a)&#160;&#160;&#160;&#160;&#160;Except
as otherwise required by law, and subject to the voting rights provided to the
holders of any series of Preferred Stock, the holders of Common Stock shall have
full voting rights and powers to vote on all matters submitted to stockholders
of the Corporation for vote, consent or approval, and each holder of Common
Stock shall be entitled to one vote for each share of Common Stock held of
record by such holder.</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 18pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(b)&#160;&#160;&#160;&#160;&#160;Each
share of Common Stock issued and outstanding shall be identical in all respects
with each other such share, and no dividends shall be paid on any shares of
Common Stock unless the same dividend is paid on all shares of Common Stock
outstanding at the time of such payment. Except for and subject to those rights
expressly granted to the holders of Preferred Stock and except as may be
provided by the laws of the State of Delaware, the holders of Common Stock shall
have all other rights of stockholders, including, without limitation, (a) the
right to receive dividends, when and as declared by the Board of Directors, out
of assets lawfully available therefor, and (b) in the event of any distribution
of assets upon a liquidation or otherwise, the right to receive ratably and
equally all the assets and funds of the Corporation remaining after the payment
to the holders of the Preferred Stock or of any other class or series of stock
ranking senior to the Common Stock upon liquidation of the specific preferential
amounts which they are entitled to receive upon such liquidation.</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 54pt; TEXT-INDENT: 18pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Upon this
Certificate of Amendment to the Amended and Restated Certificate
of&#160;Incorporation of the Corporation becoming effective pursuant&#160;to the
General Corporation Law of the State of Delaware (the &#8220;Effective Time&#8221;), each
share of the Corporation's common stock, par value $.0025 per share (the "Old
Common Stock"), issued and outstanding immediately prior to the Effective Time,
will be automatically reclassified as and converted into&#160;one thirtieth
(1/30) of a share of common stock, par value $.0025 per share, of the
Corporation (the "New Common Stock").&#160;&#160;Any stock certificate that,
immediately prior to the Effective&#160;Time, represented shares of the Old
Common Stock will, from and after the Effective Time, automatically and without
the necessity of presenting the same for exchange, represent the number of
shares of the New Common Stock as equals the product obtained by multiplying the
number of shares of Old Common Stock represented by such certificate immediately
prior to the Effective Time by one thirtieth (1/30).</font></div>
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amendment of the certificate of incorporation herein certified has been duly
adopted and written consent has been given in accordance with the provisions of
Section 242 of the General Corporation Law of the State of
Delaware.</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><font id="TAB1" style="MARGIN-LEFT: 36pt"></font>The effective time of the amendment
herein certified shall be June 29, 2009.</font></div>
    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><font id="TAB1" style="MARGIN-LEFT: 36pt"></font><font style="DISPLAY: inline; FONT-WEIGHT: bold">IN WITNESS WHEREOF, </font>the
corporation has caused this Certificate of Amendment of the corporation&#8217;s
Certificate of Incorporation to be signed by Ellen R. Hoffing, its Chief
Executive Officer this 5th day of June, 2009.</font></div>
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    <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><font id="TAB1" style="MARGIN-LEFT: 180pt"></font>APPLIED NEUROSOLUTIONS,
INC.</font></div>
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Hoffing</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font></div>
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form8kamendcertofincorp.htm
UNITED
STATES
SECURITIES
AND EXCHANGE COMMISSION
Washington,
D.C.  20549
FORM
8-K
CURRENT
REPORT
PURSUANT
TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
Date
of Report (Date of earliest event reported)
June 5,
2009
APPLIED
NEUROSOLUTIONS, INC.
(Exact
name of Registrant as Specified in its Charter)
Delaware                                   001-13835                                  39-1661164
(State
or Other Jurisdiction     (Commission file
Number)    (IRS Employer
of  Incorporation)                                                           Identification
No.)
50
Lakeview Parkway, Suite 111, Vernon Hills,
IL                               60061
(Address
of Principal Executive
Offices)                                             (Zip
Code)
Registrant's
telephone number, including area code
(847)
573-8000
Check the
appropriate box below if the Form 8-K filing is intended to simultaneously
satisfy the filing obligation of the registrant under any of the following
provisions (see General Instruction A.2. below):
|_|
Written communications pursuant to Rule 425 under the Securities Act (17 CFR
230.425)
|_|
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
240.14a-12)
|_|
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act
(17 CFR 240.14d-2(b))
|_|
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act
(17 CFR 240.13e-4(c))
Section 5 – Corporate
      Governance and Management
Item
5.03.  Amendments to Articles of Incorporation or Bylaws; Change in
Fiscal Year.
On June
5, 2009, the Registrant filed a Certificate of Amendment to its Amended and
Restated Certificate of Incorporation with the Delaware Secretary of State which
serves to effect, as of June 29, 2009, a 1-for-30 reverse split of the
Registrant's common stock.  As a result of the reverse stock split,
every 30 shares of the Registrant's common stock will be combined into one share
of common stock, and any fractional shares created by the reverse stock split
will be rounded up to whole shares.  The reverse stock split affects
all of the Registrant's common stock, stock options and warrants outstanding
immediately prior to the effective date of the reverse stock
split.  The reverse split, which was approved by the Registrant's
stockholders at the annual meeting held on September 16, 2008, will reduce the
number of shares of the Registrant's common stock outstanding from 130,217,808
shares to approximately 4,342,000 shares, and the number of authorized shares of
common stock will be reduced from 200,000,000 shares to 100,000,000 shares. The
Certificate of Amendment is filed as Exhibit 2.1 hereto.
Item
9.01  Financial Statements and Exhibits.
(d)         Exhibits.
2.1              Certificate
of Amendment to the Amended and Restated Certificate of Incorporation of Applied
NeuroSolutions, Inc. filed June 5, 2009.
SIGNATURES
Pursuant
to the requirements of the Securities Exchange Act of 1934, the registrant has
duly caused this report to be signed on its behalf by the undersigned hereunto
duly authorized on this 10th day of June 2009.
APPLIED
NEUROSOLUTIONS, INC.
By:
/s/    David
Ellison
Name:  David
Ellison
Title:    Chief
Financial Officer
EXHIBIT
2.1
CERTIFICATE
OF AMENDMENT
OF
AMENDED
AND RESTATED CERTIFICATE OF INCORPORATION
OF
APPLIED
NEUROSOLUTIONS, INC.
(a
Delaware corporation)
Applied NeuroSolutions, Inc. (the
"Corporation"), a corporation duly organized and existing under the laws of the
State of Delaware, does hereby certify as follows:
1.           The
Amended and Restated Certificate of Incorporation of the Corporation is hereby
amended by deleting Article 4 thereof in its entirety and inserting the
following in lieu thereof:
ARTICLE
4
4.1
Authorized
Stock
.
The total
number of shares of all classes of stock that the Corporation shall have
authority to issue is 105,000,000 consisting solely of:
100,000,000
shares of common stock, $.0025 par value per share ("Common Stock");
and
5,000,000
shares of preferred stock, $.0025 par value per share ("Preferred
Stock").
The
following is a statement of the powers, designations, preferences, privileges,
and relative, participating, optional, and other special rights of the Preferred
Stock and Common Stock, respectively.
4.2
Preferred
Stock
.
The Board
of Directors is hereby expressly authorized to provide for, designate and issue,
out of the authorized but unissued shares of Preferred Stock, one or more series
of Preferred Stock, subject to the terms and conditions set forth
herein.  Before any shares of any series of Preferred Stock are
issued, the Board of Directors shall fix, and hereby is expressly empowered to
fix, by resolution or resolutions, the following provisions of the shares of any
such series:
(a)     the
designation of such series, the number of shares to constitute such series, and
the stated value thereof if different from the par value;
(b)     whether
the shares of such series shall have voting rights or powers, in addition to any
voting rights required by law, and, if so, the terms of such voting rights or
powers, which may be full or limited;
(c)     the
dividends, if any, payable on such series, whether any such dividends shall be
cumulative, and, if so, from what dates, the conditions and dates upon which
such dividends shall be payable, the preference or relation which such dividends
shall bear to the dividends payable on any shares of stock of any other class or
series;
(d)     whether
the shares of such class or series shall be subject to redemption by the
Corporation, and, if so, the times, prices and other conditions of such
redemption;
(e)     the
amount or amounts payable with respect to shares of such class or series upon,
and the rights of the holders of such class or series in, the voluntary or
involuntary liquidations, dissolution or winding up, or upon any distribution of
the assets, of the Corporation;
(f)     whether
the shares of such class or series shall be subject to the operation of a
retirement or sinking fund and, if so, the extent to and manner in which any
such retirement or sinking fund shall be applied to the purchase or redemption
of the shares of such class or series for retirement or other corporate purposes
and the terms and provisions relative to the operation thereof;
(g)     whether
the shares of such class or series shall be convertible into, or exchangeable
for, shares of stock of any other class or series of any other securities and,
if so, the price or prices or the rate or rates of conversion or exchange and
the method, if any, of adjusting the same, and any other terms and conditions of
conversion or exchange;
(h)     the
limitations and restrictions, if any, to be effective while any shares of such
class or series are outstanding upon the payment of dividends or the making of
other distributions on, and upon the purchase, redemption or other acquisition
by the Corporation of, the Common Stock or shares of stock of any other class or
series;
(i)     the
conditions or restrictions, if any, to be effective while any shares of such
class or series are outstanding upon the creation of indebtedness of the
Corporation or upon the issue of any additional stock, including additional
shares of such class or series or of any other class or series; and
(j)     any
other powers, designations, preferences and relative, participating, optional or
other special rights, and any qualifications, limitations or restrictions
thereof.
The
powers, designations, preferences and relative, participating, optional or other
special rights of each series of Preferred Stock, and the qualifications,
limitations or restrictions thereof, if any, may differ from those of any and
all other series at any time outstanding. The Board of Directors is hereby
expressly authorized from time to time to increase (but not above the total
number of authorized shares of Preferred Stock) or decrease (but not below the
number of shares thereof then outstanding) the number of shares of stock of any
series of Preferred Stock designated to any one or more series of Preferred
stock pursuant to this Section 4.2. Different series of Preferred Stock shall
not be construed to constitute different classes of stock for purposes of voting
by classes unless expressly so provided in the resolution or resolutions adopted
by the Board of Directors creating or establishing any such series of Preferred
Stock. No resolution, vote, or consent of the holders of the capital stock of
the Corporation shall be required in connection with the creation or issuance of
any shares of any series of Preferred stock authorized by and complying with the
conditions of this Certificate of Incorporation, the right to any such
resolution, vote, or consent being expressly waived by all present and future
holders of the capital stock of the Corporation.
At such
time as no shares of any series of Preferred Stock that may be issued from time
to time remain issued and outstanding, including without limitation because all
of such shares have been converted into shares of Common Stock in accordance
with this Certificate of Incorporation, all authorized shares of such series of
Preferred Stock, automatically and without further actions, shall be
reclassified as authorized but unissued shares of undesignated Preferred Stock
of no particular class or series, and any and all of such shares may thereafter
be issued by the Board of Directors of the Company in one or more series, and
the terms of any such series may be determined by the Board of Directors, as
provided in this Section 4.2.
4.3
Common
Stock
.
(a)     Except
as otherwise required by law, and subject to the voting rights provided to the
holders of any series of Preferred Stock, the holders of Common Stock shall have
full voting rights and powers to vote on all matters submitted to stockholders
of the Corporation for vote, consent or approval, and each holder of Common
Stock shall be entitled to one vote for each share of Common Stock held of
record by such holder.
(b)     Each
share of Common Stock issued and outstanding shall be identical in all respects
with each other such share, and no dividends shall be paid on any shares of
Common Stock unless the same dividend is paid on all shares of Common Stock
outstanding at the time of such payment. Except for and subject to those rights
expressly granted to the holders of Preferred Stock and except as may be
provided by the laws of the State of Delaware, the holders of Common Stock shall
have all other rights of stockholders, including, without limitation, (a) the
right to receive dividends, when and as declared by the Board of Directors, out
of assets lawfully available therefor, and (b) in the event of any distribution
of assets upon a liquidation or otherwise, the right to receive ratably and
equally all the assets and funds of the Corporation remaining after the payment
to the holders of the Preferred Stock or of any other class or series of stock
ranking senior to the Common Stock upon liquidation of the specific preferential
amounts which they are entitled to receive upon such liquidation.
Upon this
Certificate of Amendment to the Amended and Restated Certificate
of Incorporation of the Corporation becoming effective pursuant to the
General Corporation Law of the State of Delaware (the "Effective Time"), each
share of the Corporation's common stock, par value $.0025 per share (the "Old
Common Stock"), issued and outstanding immediately prior to the Effective Time,
will be automatically reclassified as and converted into one thirtieth
(1/30) of a share of common stock, par value $.0025 per share, of the
Corporation (the "New Common Stock").  Any stock certificate that,
immediately prior to the Effective Time, represented shares of the Old
Common Stock will, from and after the Effective Time, automatically and without
the necessity of presenting the same for exchange, represent the number of
shares of the New Common Stock as equals the product obtained by multiplying the
number of shares of Old Common Stock represented by such certificate immediately
prior to the Effective Time by one thirtieth (1/30).
2.           The
amendment of the certificate of incorporation herein certified has been duly
adopted and written consent has been given in accordance with the provisions of
Section 242 of the General Corporation Law of the State of
Delaware.
The effective time of the amendment
herein certified shall be June 29, 2009.
IN WITNESS WHEREOF,
the
corporation has caused this Certificate of Amendment of the corporation's
Certificate of Incorporation to be signed by Ellen R. Hoffing, its Chief
Executive Officer this 5th day of June, 2009.
APPLIED NEUROSOLUTIONS,
INC.
By:
/s/Ellen R.
Hoffing
Ellen R.
Hoffing, Chief Executive Officer