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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>UNITED STATES</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>SECURITIES AND EXCHANGE COMMISSION</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Washington, D.C.&nbsp;20549</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>FORM 8-K</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>CURRENT REPORT</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Pursuant to Section 13 or 15(d) of the
Securities Exchange Act of 1934</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Date of Report&nbsp;&nbsp;(Date of Earliest
Event Reported):&nbsp; <B>&nbsp;September 6, 2012</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>CNS RESPONSE, INC.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Exact name of Company as specified in its
charter)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
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    <TD STYLE="width: 30%; vertical-align: top; padding-right: 0.8pt; font-weight: bold; text-align: center"><B>Delaware</B></TD>
    <TD STYLE="width: 5%; vertical-align: bottom; padding-right: 0.8pt">&nbsp;</TD>
    <TD STYLE="width: 30%; vertical-align: top; padding-right: 0.8pt; font-weight: bold; text-align: center"><B>0-26285</B></TD>
    <TD STYLE="width: 5%; vertical-align: bottom; padding-right: 0.8pt">&nbsp;</TD>
    <TD STYLE="width: 30%; vertical-align: top; padding-right: 0.8pt; font-weight: bold; text-align: center"><B>87-0419387</B></TD></TR>
<TR>
    <TD STYLE="vertical-align: top; padding-right: 0.8pt; text-align: center">(State or other</TD>
    <TD STYLE="vertical-align: bottom; padding-right: 0.8pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding-right: 0.8pt; text-align: center">(Commission File No.)</TD>
    <TD STYLE="vertical-align: bottom; padding-right: 0.8pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding-right: 0.8pt; text-align: center">(I.R.S. Employer</TD></TR>
<TR>
    <TD STYLE="vertical-align: top; padding-right: 0.8pt; text-align: center">&nbsp;jurisdiction of</TD>
    <TD STYLE="vertical-align: bottom; padding-right: 0.8pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding-right: 0.8pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding-right: 0.8pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding-right: 0.8pt; text-align: center">Identification No.)</TD></TR>
<TR>
    <TD STYLE="vertical-align: top; padding-right: 0.8pt; text-align: center">incorporation)</TD>
    <TD STYLE="vertical-align: bottom; padding-right: 0.8pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding-right: 0.8pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding-right: 0.8pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding-right: 0.8pt">&nbsp;</TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>85 Enterprise, Suite 410</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Aliso Viejo, CA&nbsp;92656</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Address of principal executive offices)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(714) 545-3288</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Registrant&rsquo;s telephone number, including
area code)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Not Applicable</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Former name or former address, if changed
since last report)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Check the appropriate box below if the Form 8-K filing is intended
to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

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    <TD STYLE="width: 4%; padding-right: 0.8pt"><FONT STYLE="font-family: Wingdings">&#168;</FONT></TD>
    <TD STYLE="width: 96%; padding-right: 0.8pt">Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)</TD></TR>
</TABLE>
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<TR STYLE="vertical-align: top">
    <TD STYLE="width: 4%; padding-right: 0.8pt"><FONT STYLE="font-family: Wingdings">&#168;</FONT></TD>
    <TD STYLE="width: 96%; padding-right: 0.8pt">Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)</TD></TR>
</TABLE>
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    <TD STYLE="width: 4%; padding-right: 0.8pt"><FONT STYLE="font-family: Wingdings">&#168;</FONT></TD>
    <TD STYLE="width: 96%; padding-right: 0.8pt">Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))</TD></TR>
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    <TD STYLE="width: 4%; padding-right: 0.8pt"><FONT STYLE="font-family: Wingdings">&#168;</FONT></TD>
    <TD STYLE="width: 96%; padding-right: 0.8pt">Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))</TD></TR>
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    <TD STYLE="width: 12%; padding-right: 0.8pt; font-weight: bold"><B>Item 1.01</B></TD>
    <TD STYLE="width: 88%; padding-right: 0.8pt; font-weight: bold"><B>Entry into a Material Definitive Agreement.</B></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">The description of the August 2012 Bridge Financing Purchase
Agreement (as defined below) is incorporated by reference to Item 2.03 hereof and of the August 8-K (as defined below).&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 12%; padding-right: 0.8pt; font-weight: bold"><B>Item 2.03</B></TD>
    <TD STYLE="width: 88%; padding-right: 0.8pt; font-weight: bold"><B>Creation of a Direct Financial Obligation&nbsp;or an Obligation under an Off-Balance Sheet Arrangement of a Registrant.</B></TD></TR>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">As previously disclosed, on August
17, 21 and 22, 2012, CNS Response, Inc. (the &ldquo;Company&rdquo;) issued senior secured convertible promissory notes (the
&ldquo;August 2012 Bridge Notes&rdquo;) pursuant to a new Note Purchase Agreement (the &ldquo;Bridge Financing Purchase
Agreement&rdquo;) in connection with a bridge financing (the &ldquo;Bridge Financing&rdquo;). On September 6, 2012, the
Company issued to an accredited investor, pursuant to the Bridge Financing Purchase Agreement, a fifth August 2012 Bridge
Note in the aggregate principal amount of $100,000 for gross proceeds to the Company of $100,000. This investor had
previously been issued an August 2012 Bridge Note for $100,000 on August 21, 2012. This brings the aggregate principal amount
of August 2012 Bridge Notes issued to $400,000.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">The Bridge Financing Purchase Agreement
provides for the issuance and sale of August 2012 Bridge Notes in the aggregate principal amount of up to $2,000,000, in one or
multiple closings to occur no later than October 15, 2012. The Bridge Financing Purchase Agreement also provides that the Company
and the holders of the August 2012 Bridge Notes will enter into a registration rights agreement covering the registration of the
resale of the shares underlying the August 2012 Bridge Notes.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">The consummation of the Bridge Financing
and issuance of the August 2012 Bridge Notes, and corresponding security interest, must be approved by the holders of a majority
in aggregate principal amount outstanding (&ldquo;Majority Holders&rdquo;) of each tranche of our secured convertible promissory
notes issued in October and November 2010 (the &ldquo;October 2010 Notes&rdquo;), secured convertible promissory notes issued between
January and April 2011 (the &ldquo;January 2011 Notes&rdquo;), secured convertible promissory notes issued between October 2011
and January 2012 (the &ldquo;October 2011 Notes&rdquo;) and an unsecured convertible promissory note issued in February 2012 (the
&ldquo;February 2012 Note&rdquo;). If the Company does not obtain such consent, the holders could declare a default under such
notes and seek all remedies available under such notes. So far, the Company has received indications from the Majority Holders
of each of the tranches of notes that they would approve the Bridge Financing, issuance of the August 2012 Bridge Notes, and corresponding
security interest; however, it is still negotiating the precise terms of the related approval and there can be no assurances that
the Company will obtain such approval. The October 2010 Notes and January 2011 Notes are repayable on October 1, 2012, the October
2011 Notes are repayable beginning October 18, 2012, and the February 2012 Note is repayable on February 28, 2013. The Company
currently does not have sufficient funds to repay these tranches of notes.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">The description of the terms of the August
2012 Bridge Notes, Bridge Financing Purchase Agreement and the second amended and restated security agreement, dated as of August
16, 2012, between the Company and David Jones, as administrative agent for the secured parties (the &ldquo;Second Amended and Restated
Security Agreement&rdquo;) is incorporated herein by reference to Item 2.03 of the Company&rsquo;s Current Report on Form 8-K filed
on August 24, 2012 (the &ldquo;August 8-K&rdquo;), and is qualified in its entirety by reference to the forms of the August 2012
Bridge Note, Bridge Financing Purchase Agreement, and Second Amended and Restated Security Agreement, filed as Exhibits 4.1, 10.1
and 10.2, respectively, to the August 8-K, which are incorporated herein by reference.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 12%; padding-right: 0.8pt; font-weight: bold"><B>Item 3.02</B></TD>
    <TD STYLE="width: 88%; padding-right: 0.8pt; font-weight: bold"><B>Unregistered Sales of Equity Securities.</B></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">The description of the August 2012 Bridge Notes is incorporated
herein by reference to Item 2.03 of the August 8-K and the full text of the form of August 2012 Bridge Note is incorporated herein
by reference to Exhibit 4.1 to the August 8-K.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">The August 2012 Bridge Notes were issued by the Company under
the exemption from registration afforded by Section 4(2) of the Securities Act of 1933, as amended, and Regulation D promulgated
thereunder, as they were issued to accredited investors, without a view to distribution, and were not issued through any general
solicitation or advertisement.</P>



<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>SIGNATURES</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 45pt">Pursuant to the Securities Exchange Act of
1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 45pt">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 0.8pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="padding-right: 1.8pt">CNS Response, Inc.</TD>
    <TD STYLE="padding-right: 0.8pt">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 0.8pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="padding-right: 1.8pt">&nbsp;</TD>
    <TD STYLE="padding-right: 0.8pt">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 51%; padding-right: 0.8pt">&nbsp;</TD>
    <TD STYLE="width: 3%; padding-right: 0.8pt">By:</TD>
    <TD STYLE="width: 34%; border-bottom: black 1.5pt solid; padding-right: 0.8pt">/s/ Paul Buck</TD>
    <TD STYLE="width: 12%; padding-right: 0.8pt">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 0.8pt">September 12, 2012</TD>
    <TD STYLE="padding-right: 0.8pt">&nbsp;</TD>
    <TD STYLE="padding-right: 0.8pt">Paul Buck</TD>
    <TD STYLE="padding-right: 0.8pt">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 0.8pt">&nbsp;</TD>
    <TD STYLE="padding-right: 0.8pt">&nbsp;</TD>
    <TD STYLE="padding-right: 0.8pt; font-style: italic"><I>Chief Financial Officer</I></TD>
    <TD STYLE="padding-right: 0.8pt">&nbsp;</TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>



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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the
Securities Exchange Act of 1934
Date of Report  (Date of Earliest
Event Reported):
September 6, 2012
CNS RESPONSE, INC.
(Exact name of Company as specified in its
charter)
Delaware
0-26285
87-0419387
(State or other
(Commission File No.)
(I.R.S. Employer
jurisdiction of
Identification No.)
incorporation)
85 Enterprise, Suite 410
Aliso Viejo, CA 92656
(Address of principal executive offices)
(714) 545-3288
(Registrant's telephone number, including
area code)
Not Applicable
(Former name or former address, if changed
since last report)
Check the appropriate box below if the Form 8-K filing is intended
to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
¨
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
¨
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
¨
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
¨
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Item 1.01
Entry into a Material Definitive Agreement.
The description of the August 2012 Bridge Financing Purchase
Agreement (as defined below) is incorporated by reference to Item 2.03 hereof and of the August 8-K (as defined below).
Item 2.03
Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant.
As previously disclosed, on August
17, 21 and 22, 2012, CNS Response, Inc. (the "Company") issued senior secured convertible promissory notes (the
"August 2012 Bridge Notes") pursuant to a new Note Purchase Agreement (the "Bridge Financing Purchase
Agreement") in connection with a bridge financing (the "Bridge Financing"). On September 6, 2012, the
Company issued to an accredited investor, pursuant to the Bridge Financing Purchase Agreement, a fifth August 2012 Bridge
Note in the aggregate principal amount of $100,000 for gross proceeds to the Company of $100,000. This investor had
previously been issued an August 2012 Bridge Note for $100,000 on August 21, 2012. This brings the aggregate principal amount
of August 2012 Bridge Notes issued to $400,000.
The Bridge Financing Purchase Agreement
provides for the issuance and sale of August 2012 Bridge Notes in the aggregate principal amount of up to $2,000,000, in one or
multiple closings to occur no later than October 15, 2012. The Bridge Financing Purchase Agreement also provides that the Company
and the holders of the August 2012 Bridge Notes will enter into a registration rights agreement covering the registration of the
resale of the shares underlying the August 2012 Bridge Notes.
The consummation of the Bridge Financing
and issuance of the August 2012 Bridge Notes, and corresponding security interest, must be approved by the holders of a majority
in aggregate principal amount outstanding ("Majority Holders") of each tranche of our secured convertible promissory
notes issued in October and November 2010 (the "October 2010 Notes"), secured convertible promissory notes issued between
January and April 2011 (the "January 2011 Notes"), secured convertible promissory notes issued between October 2011
and January 2012 (the "October 2011 Notes") and an unsecured convertible promissory note issued in February 2012 (the
"February 2012 Note"). If the Company does not obtain such consent, the holders could declare a default under such
notes and seek all remedies available under such notes. So far, the Company has received indications from the Majority Holders
of each of the tranches of notes that they would approve the Bridge Financing, issuance of the August 2012 Bridge Notes, and corresponding
security interest; however, it is still negotiating the precise terms of the related approval and there can be no assurances that
the Company will obtain such approval. The October 2010 Notes and January 2011 Notes are repayable on October 1, 2012, the October
2011 Notes are repayable beginning October 18, 2012, and the February 2012 Note is repayable on February 28, 2013. The Company
currently does not have sufficient funds to repay these tranches of notes.
The description of the terms of the August
2012 Bridge Notes, Bridge Financing Purchase Agreement and the second amended and restated security agreement, dated as of August
16, 2012, between the Company and David Jones, as administrative agent for the secured parties (the "Second Amended and Restated
Security Agreement") is incorporated herein by reference to Item 2.03 of the Company's Current Report on Form 8-K filed
on August 24, 2012 (the "August 8-K"), and is qualified in its entirety by reference to the forms of the August 2012
Bridge Note, Bridge Financing Purchase Agreement, and Second Amended and Restated Security Agreement, filed as Exhibits 4.1, 10.1
and 10.2, respectively, to the August 8-K, which are incorporated herein by reference.
Item 3.02
Unregistered Sales of Equity Securities.
The description of the August 2012 Bridge Notes is incorporated
herein by reference to Item 2.03 of the August 8-K and the full text of the form of August 2012 Bridge Note is incorporated herein
by reference to Exhibit 4.1 to the August 8-K.
The August 2012 Bridge Notes were issued by the Company under
the exemption from registration afforded by Section 4(2) of the Securities Act of 1933, as amended, and Regulation D promulgated
thereunder, as they were issued to accredited investors, without a view to distribution, and were not issued through any general
solicitation or advertisement.
SIGNATURES
Pursuant to the Securities Exchange Act of
1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
CNS Response, Inc.
By:
/s/ Paul Buck
September 12, 2012
Paul Buck
Chief Financial Officer