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<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 5pt 0; text-align: center">UNITED STATES<BR>
SECURITIES AND EXCHANGE COMMISSION<BR>
Washington, DC 20549</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 5pt 0; text-align: center">FORM 8-K</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 5pt 0; text-align: center">CURRENT REPORT<BR>
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934</P>

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    <TD COLSPAN="3" STYLE="padding-right: 1.85pt; padding-left: 1.85pt; font-size: 10pt; text-align: center">Date of Report (Date of earliest event reported) <U>February 2, 2012</U></TD></TR>
<TR>
    <TD COLSPAN="3" STYLE="padding-right: 1.85pt; padding-left: 1.85pt; font-size: 10pt; text-align: center"><BR STYLE="mso-special-character: line-break">&nbsp;</TD></TR>
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    <TD COLSPAN="3" STYLE="padding-right: 1.85pt; padding-left: 1.85pt; font-size: 10pt; font-weight: bold; text-align: center"><U>OxySure
    Systems, Inc.<BR></U> (Exact name of registrant as specified in its chapter)</TD></TR>
<TR>
    <TD COLSPAN="3" STYLE="padding-right: 1.85pt; padding-left: 1.85pt; font-size: 10pt; text-align: center"><BR STYLE="mso-special-character: line-break"><BR STYLE="mso-special-character: line-break">&nbsp;</TD></TR>
<TR>
    <TD STYLE="width: 33%; padding-right: 1.85pt; padding-left: 1.85pt; font-size: 10pt; text-align: center"><U>Delaware</U> <BR>
    (State or other jurisdiction <BR> of incorporation</TD>
    <TD STYLE="width: 34%; padding-right: 1.85pt; padding-left: 1.85pt; font-size: 10pt; text-align: center"><U>000-54137<BR>
    </U>(Commission <BR> File Number)</TD>
    <TD STYLE="width: 33%; padding-right: 1.85pt; padding-left: 1.85pt; font-size: 10pt; text-align: center"><U>71-0960725<BR>
    </U>(IRS Employer <BR> Identification No.)</TD></TR>
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    <TD STYLE="width: 62%">
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><U>10880 John W. Elliott Drive, Suite
        600, Frisco, TX</U></P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">(Address of principal executive offices)</P></TD>
    <TD STYLE="width: 38%; font-size: 10pt; text-align: center"><U>75033<BR></U> (Zip Code)</TD></TR>
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    <TD COLSPAN="2" STYLE="font-size: 10pt; text-align: center"><BR STYLE="mso-special-character: line-break">&nbsp;</TD></TR>
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    <TD STYLE="width: 100%">
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><U>(972) 294-6450</U></P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">Registrant's telephone number, including area
        code</P></TD></TR>
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    <TD>&nbsp;</TD></TR>
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    <TD STYLE="border-bottom: Black 1pt solid">&nbsp;</TD></TR>
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    <TD STYLE="font-size: 10pt; text-align: center; vertical-align: bottom">(Former name or former address, if changed since last report)&nbsp;</TD></TR>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Check the appropriate box below if the Form
8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:</P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0pt"><FONT STYLE="font-family: Wingdings 2">&#163;</FONT>
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)</P>

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Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)</P>

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Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))</P>

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Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))</P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: left">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: left">Section 1 &ndash; Registrant&rsquo;s Business
and Operations</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Item 2.03 Creation of a Direct Financial Obligation or an Obligation
under an Off-Balance Sheet Arrangement of a Registrant</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">On January 29, 2012, OxySure Systems, Inc. (the &ldquo;Company&rdquo;)
entered into a Note Purchase Agreement (the &ldquo;Agreement&rdquo;) with the M. Nyewe Trust (the &ldquo;Nyewe Trust&rdquo;).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">The Agreement provides that the Nyewe Trust purchase a subordinated
convertible promissory note (the Note&rdquo;) from the Company for cash. The salient terms of the Note are as follows:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Principal amount (&ldquo;Principal Amount &ldquo;) of the Note:
$100,000</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Interest rate: 8% per annum</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Maturity: The then outstanding Principal Amount, together with accrued
and unpaid interest thereon, or the optional conversion shares (&ldquo;Optional Conversion Shares&rdquo;) as the case may be, is
due on the 360th day subsequent to January 29, 2012 (the &quot;Maturity Date&quot;).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Conversion: The Note is convertible, at the option of either the
Company or the Nyewe Trust, at any time on or prior to the Maturity Date. All or any portion of the then outstanding Principal
Amount and accrued but unpaid interest of the Note may be converted (the &quot;Optional Conversion&quot;) into a number of shares
of the Company&rsquo;s common stock (the &quot;Optional Conversion Shares&quot;) equal to the amount of the then outstanding Principal
Amount plus the then accrued but unpaid interest to be converted, divided by the conversion price, which is $1.50 per Optional
Conversion Share.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>SIGNATURES</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Pursuant to the requirements of the Securities
Exchange Act of 1934, the Registrant has duly caused this report on Form 8-K to be signed on its behalf by the undersigned hereunto
duly authorized.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

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    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="padding-right: 5.4pt; padding-left: 5.4pt">Date: February 2, 2012</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; width: 50%">&nbsp;</TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; width: 6%">&nbsp;</TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt; width: 44%">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="padding-right: 5.4pt; padding-left: 5.4pt">OXYSURE SYSTEMS, INC.,</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="padding-right: 5.4pt; padding-left: 5.4pt">a Delaware corporation</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="padding-right: 5.4pt; padding-left: 5.4pt; border-bottom: Black 1pt solid">/s/ Julian T.
    Ross</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">BY:</TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">Julian T. Ross</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">ITS:</TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">Chief Executive Officer, President,</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">Chief Financial Officer, and Secretary</TD></TR>
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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, DC 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
Date of Report (Date of earliest event reported)
February 2, 2012
OxySure
    Systems, Inc.
(Exact name of registrant as specified in its chapter)
Delaware
(State or other jurisdiction
of incorporation
000-54137
(Commission
File Number)
71-0960725
(IRS Employer
Identification No.)
10880 John W. Elliott Drive, Suite
        600, Frisco, TX
(Address of principal executive offices)
75033
(Zip Code)
(972) 294-6450
Registrant's telephone number, including area
        code
(Former name or former address, if changed since last report)
Check the appropriate box below if the Form
8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
£
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
£
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
£
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
£
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Section 1 – Registrant's Business
and Operations
Item 2.03 Creation of a Direct Financial Obligation or an Obligation
under an Off-Balance Sheet Arrangement of a Registrant
On January 29, 2012, OxySure Systems, Inc. (the "Company")
entered into a Note Purchase Agreement (the "Agreement") with the M. Nyewe Trust (the "Nyewe Trust").
The Agreement provides that the Nyewe Trust purchase a subordinated
convertible promissory note (the Note") from the Company for cash. The salient terms of the Note are as follows:
Principal amount ("Principal Amount ") of the Note:
$100,000
Interest rate: 8% per annum
Maturity: The then outstanding Principal Amount, together with accrued
and unpaid interest thereon, or the optional conversion shares ("Optional Conversion Shares") as the case may be, is
due on the 360th day subsequent to January 29, 2012 (the "Maturity Date").
Conversion: The Note is convertible, at the option of either the
Company or the Nyewe Trust, at any time on or prior to the Maturity Date. All or any portion of the then outstanding Principal
Amount and accrued but unpaid interest of the Note may be converted (the "Optional Conversion") into a number of shares
of the Company's common stock (the "Optional Conversion Shares") equal to the amount of the then outstanding Principal
Amount plus the then accrued but unpaid interest to be converted, divided by the conversion price, which is $1.50 per Optional
Conversion Share.
SIGNATURES
Pursuant to the requirements of the Securities
Exchange Act of 1934, the Registrant has duly caused this report on Form 8-K to be signed on its behalf by the undersigned hereunto
duly authorized.
Date: February 2, 2012
OXYSURE SYSTEMS, INC.,
a Delaware corporation
/s/ Julian T.
    Ross
BY:
Julian T. Ross
ITS:
Chief Executive Officer, President,
Chief Financial Officer, and Secretary
2