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<P STYLE="font: 18pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>UNITED STATES<BR>
SECURITIES AND EXCHANGE COMMISSION</B></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">WASHINGTON, D.C. 20549</P>

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<P STYLE="font: 18pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>FORM 8-K</B></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Current Report Pursuant to Section 13 or
15(d) of the<BR>
Securities Exchange Act of 1934</P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Date of Report (Date of earliest event
reported) April 17, 2012</B></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-size: 18pt"><B>GENESIS
BIOPHARMA, INC<BR>
</B></FONT><FONT STYLE="font-size: 10pt">(EXACT NAME OF COMPANY AS SPECIFIED IN ITS CHARTER)</FONT></P>

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    <TD STYLE="width: 33%; padding-right: -0.45pt; padding-left: 5.4pt; text-align: center">NEVADA</TD>
    <TD STYLE="width: 33%; padding-right: -0.45pt; padding-left: 5.4pt; text-align: center">000-53172</TD>
    <TD STYLE="width: 33%; padding-right: -0.45pt; padding-left: 5.4pt; text-align: center">75-3254381</TD></TR>
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    <TD STYLE="padding-right: -0.45pt; padding-left: 5.4pt; text-align: center">(STATE OR OTHER JURISDICTION)</TD>
    <TD STYLE="padding-right: -0.45pt; padding-left: 5.4pt; text-align: center">(COMMISSION FILE NUMBER)</TD>
    <TD STYLE="padding-right: -0.45pt; padding-left: 5.4pt; text-align: center">(I.R.S. EMPLOYER</TD></TR>
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    <TD STYLE="padding-right: -0.45pt; padding-left: 5.4pt; text-align: center">OF INCORPORATION)</TD>
    <TD STYLE="padding-right: -0.45pt; padding-left: 5.4pt; text-align: center">&nbsp;</TD>
    <TD STYLE="padding-right: -0.45pt; padding-left: 5.4pt; text-align: center">IDENTIFICATION)</TD></TR>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>11500 Olympic Boulevard, Suite 400, Los
Angeles CA 90064</B></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Address of principal executive offices)
(Zip Code)</P>

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area code: (866) 963-2220</P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">N/A</P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Former name or former address, if changed
since last report)</P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 42.75pt"> <FONT STYLE="font-family: Wingdings">&#168;</FONT>
Written communication pursuant to Rule 425 under the Securities Act (17 CFR 230.425)</P>

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Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)</P>

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Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))</P>

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Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 40.13e-4(c))</P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>ITEM 1.01 ENTRY INTO A MATERIAL DEFINITIVE AGREEMENT.</B></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Effective April 17, 2012, Genesis Biopharma, Inc. (the &ldquo;Company&rdquo;)
entered into a ninth amendment with all the holders of the Company&rsquo;s previously issued 7% Tranche A Senior Unsecured Convertible
Notes and Tranche B Senior Unsecured Convertible Notes (the &ldquo;Notes&rdquo;) whereby the maturity date of the Notes has been
further extended from April 17, 2012 to May 11, 2012.</P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>SIGNATURES</B>&nbsp;</P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Pursuant to the requirements of the Securities Exchange Act
of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.</P>

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    <TD COLSPAN="2" STYLE="padding: 0; text-indent: 0">GENESIS BIOPHARMA, INC.</TD>
    <TD STYLE="padding: 0; text-indent: 0">&nbsp;</TD></TR>
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    <TD STYLE="padding: 0; text-indent: 0">Date: April 23, 2012</TD>
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    <TD STYLE="padding: 0; text-indent: 0">&nbsp;</TD></TR>
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    <TD STYLE="padding: 0; text-indent: 0">&nbsp;</TD>
    <TD STYLE="padding: 0; text-indent: 0">By:</TD>
    <TD STYLE="padding: 0; text-indent: 0; border-bottom: Black 1pt solid">/s/ Anthony J. Cataldo</TD>
    <TD STYLE="padding: 0; text-indent: 0">&nbsp;</TD></TR>
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    <TD STYLE="padding: 0; text-indent: 0">&nbsp;</TD>
    <TD STYLE="padding: 0; text-indent: 0">&nbsp;</TD>
    <TD STYLE="padding: 0; text-indent: 0">Anthony J. Cataldo, Chief Executive</TD>
    <TD STYLE="padding: 0; text-indent: 0">&nbsp;</TD></TR>
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    <TD STYLE="padding: 0; text-indent: 0">&nbsp;</TD>
    <TD STYLE="padding: 0; text-indent: 0">&nbsp;</TD>
    <TD STYLE="padding: 0; text-indent: 0">Officer and President</TD>
    <TD STYLE="padding: 0; text-indent: 0">&nbsp;</TD></TR>
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{"company-data": {"conformed-name": "Genesis Biopharma, Inc", "cik": "0001425205", "assigned-sic": "4731", "irs-number": "753254381", "state-of-incorporation": "NV", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "000-53127", "film-number": "12773558"}, "business-address": {"street1": "1601 N. SEPULVEDA BLVD., #632", "city": "MANHATTAN BEACH", "state": "CA", "zip": "90266", "phone": "866-963-2220"}, "mail-address": {"street1": "1601 N. SEPULVEDA BLVD., #632", "city": "MANHATTAN BEACH", "state": "CA", "zip": "90266"}, "former-company": {"former-conformed-name": "FREIGHT MANAGEMENT CORP", "date-changed": "20080128"}}
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
FORM 8-K
Current Report Pursuant to Section 13 or
15(d) of the
Securities Exchange Act of 1934
Date of Report (Date of earliest event
reported) April 17, 2012
GENESIS
BIOPHARMA, INC
(EXACT NAME OF COMPANY AS SPECIFIED IN ITS CHARTER)
NEVADA
000-53172
75-3254381
(STATE OR OTHER JURISDICTION)
(COMMISSION FILE NUMBER)
(I.R.S. EMPLOYER
OF INCORPORATION)
IDENTIFICATION)
11500 Olympic Boulevard, Suite 400, Los
Angeles CA 90064
(Address of principal executive offices)
(Zip Code)
Registrant's telephone number, including
area code: (866) 963-2220
N/A
(Former name or former address, if changed
since last report)
¨
Written communication pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
¨
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
¨
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
¨
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 40.13e-4(c))
ITEM 1.01 ENTRY INTO A MATERIAL DEFINITIVE AGREEMENT.
Effective April 17, 2012, Genesis Biopharma, Inc. (the "Company")
entered into a ninth amendment with all the holders of the Company's previously issued 7% Tranche A Senior Unsecured Convertible
Notes and Tranche B Senior Unsecured Convertible Notes (the "Notes") whereby the maturity date of the Notes has been
further extended from April 17, 2012 to May 11, 2012.
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act
of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
GENESIS BIOPHARMA, INC.
Date: April 23, 2012
By:
/s/ Anthony J. Cataldo
Anthony J. Cataldo, Chief Executive
Officer and President