content: <PAGE>
   
                         SECURITIES AND EXCHANGE COMMISSION
                               Washington, D.C. 20549
  
  
  
                                      FORM 8-K
  
  
  
                 Current Report Pursuant to Section 13 or 15(d) of
                        The Securities Exchange Act of 1934
  
  
  
        Date of Report (Date of earliest event reported):  December 2, 1997
  
  
  
                               CHEMTRAK INCORPORATED
               (Exact name of registrant as specified in its charter)
  
  
  
             Delaware                       0-19749                77-0295388
  -------------------------------   ------------------------   ------------------
  (State or other jurisdiction of   (Commission File Number)    (I.R.S. Employer
          incorporation)                                       Identification No.)
  
  
                                929 E. Arques Avenue
                              Sunnyvale, CA 94086-4520
                      (Address of principal executive offices)
  
                                  (408) 773-8156
               (Registrant's telephone number, including area code)
  <PAGE>
   
  ITEM 4.   CHANGES IN REGISTRANT'S CERTIFYING ACCOUNTANT
            ---------------------------------------------
  
       On December 2, 1997, the Board of Directors voted to change independent
  public accountants, dismissing Ernst & Young LLP as the independent accountants
  for ChemTrak, Inc. (the "Company") and engaging Coopers & Lybrand LLP.  Notice
  of dismissal was delivered to Ernst & Young on December 4, 1997.
  
       During the Company's two most recent fiscal years and the subsequent
  interim period preceding the dismissal of Ernst & Young, (i) there were no
  disagreements with Ernst & Young on any matter of accounting principles or
  practices, financial statement disclosure, or auditing scope or procedures,
  which if not resolved to its satisfaction would have caused it to make reference
  in connection with its reports, and (ii) Ernst & Young has not advised the
  Company of any reportable events as defined in paragraph (A) through (D) of
  Regulation S-K Item 304(a)(1)(v).
  
       During the Company's two most recent fiscal years and the subsequent
  interim period prior to engaging Coopers & Lybrand, the Company has not
  consulted Coopers & Lybrand with respect to any of the matters described in
  Regulation S-K Item 304(a)(2)(i) or (ii).
  
  ITEM 7.  FINANCIAL STATEMENTS AND EXHIBITS
           ---------------------------------
  
            A.   Exhibits.
  
                 16.1 - Letter of Ernst & Young dated December 8, 1997 regarding
                 the disclosure contained in Item 4 of this report on Form 8-K.
  <PAGE>
   
                                     SIGNATURES
  
  
  
       Pursuant to the requirements of the Securities Exchange Act of 1934, the
  Registrant has duly caused this report to be signed on its behalf by the
  undersigned hereunto duly authorized.
  
  
                                           CHEMTRAK INCORPORATED
  
  
  Dated:    December 5, 1997               By:  /s/ Donald V. Fluken
                                                -----------------------------
                                                Donald V. Fluken
                                                Vice President, Secretary and
                                                Chief Financial Officer
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text: SECURITIES AND EXCHANGE COMMISSION
                               Washington, D.C. 20549
  
                                      FORM 8-K
  
                 Current Report Pursuant to Section 13 or 15(d) of
                        The Securities Exchange Act of 1934
  
        Date of Report (Date of earliest event reported):  December 2, 1997
  
                               CHEMTRAK INCORPORATED
               (Exact name of registrant as specified in its charter)
  
             Delaware                       0-19749                77-0295388
  -------------------------------   ------------------------   ------------------
  (State or other jurisdiction of   (Commission File Number)    (I.R.S. Employer
          incorporation)                                       Identification No.)
  
                                929 E. Arques Avenue
                              Sunnyvale, CA 94086-4520
                      (Address of principal executive offices)
  
                                  (408) 773-8156
               (Registrant's telephone number, including area code)
  ITEM 4.   CHANGES IN REGISTRANT'S CERTIFYING ACCOUNTANT
            ---------------------------------------------
  
       On December 2, 1997, the Board of Directors voted to change independent
  public accountants, dismissing Ernst & Young LLP as the independent accountants
  for ChemTrak, Inc. (the "Company") and engaging Coopers & Lybrand LLP.  Notice
  of dismissal was delivered to Ernst & Young on December 4, 1997.
  
       During the Company's two most recent fiscal years and the subsequent
  interim period preceding the dismissal of Ernst & Young, (i) there were no
  disagreements with Ernst & Young on any matter of accounting principles or
  practices, financial statement disclosure, or auditing scope or procedures,
  which if not resolved to its satisfaction would have caused it to make reference
  in connection with its reports, and (ii) Ernst & Young has not advised the
  Company of any reportable events as defined in paragraph (A) through (D) of
  Regulation S-K Item 304(a)(1)(v).
  
       During the Company's two most recent fiscal years and the subsequent
  interim period prior to engaging Coopers & Lybrand, the Company has not
  consulted Coopers & Lybrand with respect to any of the matters described in
  Regulation S-K Item 304(a)(2)(i) or (ii).
  
  ITEM 7.  FINANCIAL STATEMENTS AND EXHIBITS
           ---------------------------------
  
            A.   Exhibits.
  
                 16.1 - Letter of Ernst & Young dated December 8, 1997 regarding
                 the disclosure contained in Item 4 of this report on Form 8-K.
  SIGNATURES
  
       Pursuant to the requirements of the Securities Exchange Act of 1934, the
  Registrant has duly caused this report to be signed on its behalf by the
  undersigned hereunto duly authorized.
  
                                           CHEMTRAK INCORPORATED
  
  Dated:    December 5, 1997               By:  /s/ Donald V. Fluken
                                                -----------------------------
                                                Donald V. Fluken
                                                Vice President, Secretary and
                                                Chief Financial Officer