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			omer_Current_Folio_8K_Other
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			<font style="display:inline;font-weight:bold;font-size:15pt;">UNITED STATES</font>
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			<font style="display:inline;font-weight:bold;font-size:15pt;">SECURITIES AND EXCHANGE COMMISSION</font>
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			<font style="display:inline;font-weight:bold;">WASHINGTON, D.C. 20549</font>
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			<font style="display:inline;font-weight:bold;font-size:15pt;">FORM&nbsp;8-K</font>
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			<font style="display:inline;font-weight:bold;">CURRENT REPORT</font>
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			<font style="display:inline;font-weight:bold;">Pursuant to Section&nbsp;13 or 15(d)&nbsp;of the Securities Exchange Act of 1934</font>
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			<font style="display:inline;font-size:6pt;">&nbsp;</font>
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			<font style="display:inline;font-weight:bold;">Date of Report (Date of earliest event reported): July 28, 2019</font>
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			<font style="display:inline;font-weight:bold;font-size:24pt;">OMEROS CORPORATION</font>
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			<font style="display:inline;font-weight:bold;font-size:8pt;">(Exact name of Registrant as Specified in Its Charter)</font>
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						<font style="display:inline;font-weight:bold;">Washington</font></p>
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						<font style="display:inline;font-weight:bold;">001&#8209;34475</font></p>
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						<font style="display:inline;font-weight:bold;">91&#8209;1663741</font></p>
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						<font style="display:inline;font-weight:bold;font-size:8pt;">(State or Other Jurisdiction<br /></font><font style="display:inline;font-family:Times New Roman,Times,serif;font-weight:bold;font-size:8pt;">of Incorporation)</font></p>
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						<font style="display:inline;font-weight:bold;font-size:8pt;">(Commission File Number)</font></p>
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						<font style="display:inline;font-weight:bold;font-size:8pt;">(IRS Employer<br /></font><font style="display:inline;font-family:Times New Roman,Times,serif;font-weight:bold;font-size:8pt;">Identification No.)</font></p>
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			<font style="display:inline;font-size:6pt;">&nbsp;</font>
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			<font style="display:inline;font-weight:bold;">201 Elliott Avenue West</font>
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			<font style="display:inline;font-weight:bold;">Seattle, Washington</font>
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			<font style="display:inline;font-weight:bold;">98119</font>
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			<font style="display:inline;font-weight:bold;font-size:8pt;">(Address of Principal Executive Offices) (Zip Code)</font>
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			<font style="display:inline;font-size:6pt;">&nbsp;</font>
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			<font style="display:inline;font-weight:bold;">Registrant&#x2019;s Telephone Number, Including Area Code: (206) 676&#8209;5000</font>
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			<font style="display:inline;font-size:6pt;">&nbsp;</font>
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			<font style="display:inline;font-weight:bold;font-size:8pt;">(Former Name or Former Address, if Changed Since Last Report)</font>
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			<font style="display:inline;">Check the appropriate box below if the Form&nbsp;8&#8209;K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):</font>
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			<font style="display:inline;font-size:6pt;">&nbsp;</font>
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			<font style="display:inline;font-family:Segoe UI Symbol;">&#x2610;</font><font style="display:inline;">&nbsp;&nbsp;&nbsp;&nbsp;Written communications pursuant to Rule&nbsp;425 under the Securities Act (17 CFR 230.425)</font>
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			<font style="display:inline;font-size:6pt;">&nbsp;</font>
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			<font style="display:inline;font-family:Segoe UI Symbol;">&#x2610;</font><font style="display:inline;">&nbsp;&nbsp;&nbsp;&nbsp;Soliciting material pursuant to Rule&nbsp;14a-12 under the Exchange Act (17 CFR 240.14a-12)</font>
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			<font style="display:inline;font-size:6pt;">&nbsp;</font>
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			<font style="display:inline;font-family:Segoe UI Symbol;">&#x2610;</font><font style="display:inline;">&nbsp;&nbsp;&nbsp;&nbsp;Pre-commencement communications pursuant to Rule&nbsp;14d-2(b)&nbsp;under the Exchange Act (17 CFR 240.14d-2(b))</font>
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			<font style="display:inline;font-size:6pt;">&nbsp;</font>
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			<font style="display:inline;font-family:Segoe UI Symbol;">&#x2610;</font><font style="display:inline;">&nbsp;&nbsp;&nbsp;&nbsp;Pre-commencement communications pursuant to Rule&nbsp;13e-4(c)&nbsp;under the Exchange Act (17 CFR 240.13e-4(c))</font>
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			<font style="display:inline;">Securities Registered Pursuant to Section&nbsp;12(b)&nbsp;of the Act:</font>
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			<font style="display:inline;font-size:6pt;">&nbsp;</font>
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						<font style="display:inline;font-size:1pt;">&nbsp;</font></p>
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						<font style="display:inline;font-size:1pt;">&nbsp;</font></p>
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						<font style="display:inline;font-size:1pt;">&nbsp;</font></p>
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					<p style="margin:0pt;text-indent:0pt;text-align:center;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">Title of each class</font></p>
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					<p style="margin:0pt;text-indent:0pt;text-align:center;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">Trading Symbol(s)</font></p>
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					<p style="margin:0pt;text-indent:0pt;text-align:center;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">Name of each exchange on which registered</font></p>
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					<p style="margin:0pt;text-indent:0pt;text-align:center;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">Common stock, $0.01 par value per share</font></p>
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					<p style="margin:0pt;text-indent:0pt;text-align:center;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">OMER</font></p>
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					<p style="margin:0pt;text-indent:0pt;text-align:center;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">The Nasdaq Stock Market LLC</font></p>
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			<font style="display:inline;font-size:6pt;">&nbsp;</font>
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		<p style="margin:0pt;text-indent:0pt;border-bottom:1pt none #D9D9D9 ;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;">Indicate by check mark whether the registrant is an emerging growth company as defined in Rule&nbsp;405 under the Securities Act of 1933 (17 CFR&nbsp;230.405) or Rule&nbsp;12b-2&nbsp;under the Securities Exchange Act of 1934&nbsp;(17 CFR&nbsp;240.12b-2).</font>
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			<font style="display:inline;font-size:6pt;">&nbsp;</font>
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		<p style="margin:0pt;text-indent:0pt;text-align:right;border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;">Emerging growth company&nbsp;</font><font style="display:inline;font-family:Segoe UI Symbol;">&#x2610;</font>
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			<font style="display:inline;font-size:6pt;">&nbsp;</font>
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			<font style="display:inline;">If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section&nbsp;13(a)&nbsp;of the Exchange Act.&nbsp;</font><font style="display:inline;font-family:Segoe UI Symbol;">&#x2610;</font>
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			<font style="display:inline;font-size:6pt;">&nbsp;</font>
		</p>
		<p style="margin:0pt;border-top:1pt solid #000000 ;border-bottom:3pt solid #000000 ;text-indent:0pt;font-family:Times New Roman,Times,serif;font-size: 1pt;">
			<font style="display:inline;font-size:1pt;">&nbsp;</font>
		</p>
		<p style="margin:0pt;text-indent:0pt;border-bottom:1pt none #D9D9D9 ;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;font-family:Segoe UI Symbol;">&nbsp;</font>
		</p>
		<p style="margin:0pt;text-indent:0pt;border-top:1pt none #D9D9D9 ;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			&nbsp;
		</p>
		<p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;"></font></p></div><div style="margin-left:10.2941176470588%;margin-right:10.2941176470588%;">
		<p><font size="1"> </font></p></div><div style="margin-left:10.2941176470588%;margin-right:10.2941176470588%;page-break-after:always;"><div style="background-color:#000000;clear:both;height:2pt;border:0;margin:30pt 0pt 30pt 0pt;"></div></div><div style="margin-left:10.2941176470588%;margin-right:10.2941176470588%;"></div><div style="margin-left:10.2941176470588%;margin-right:10.2941176470588%;"><p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;"><font style="display:inline;"></font>
		</p>
		<p style="margin:0pt 0pt 12pt 50.4pt;text-indent: -50.4pt;font-family:Times New Roman,Times,serif;font-weight:bold;font-size: 10pt;">
			<font style="display:inline;">Item&nbsp;1.01&nbsp;&nbsp;&nbsp;&nbsp;Entry Into a Material Definitive Agreement.</font>
		</p>
		<p style="margin:0pt;text-indent:36pt;color:#000000;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;">On July 28, 2019, Omeros Corporation (&#x201C;Omeros&#x201D;) entered into a Master Services Agreement (the &#x201C;Agreement&#x201D;) with Lonza Biologics Tuas Pte. Ltd. (&#x201C;Lonza&#x201D;) for the commercial production of narsoplimab, also referred to as OMS721, Omeros&#x2019; lead human monoclonal antibody targeting mannan-binding lectin-associated serine protease-2 (MASP-2). The Agreement also provides for certain regulatory support and related services to be provided by Lonza from time to time.&nbsp;</font>
		</p>
		<p style="margin:0pt;color:#000000;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;font-family:Times New Roman,Times,serif;">&nbsp;</font>
		</p>
		<p style="margin:0pt;text-indent:36pt;color:#000000;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;">Omeros and Lonza Sales AG previously entered into a Master Services Agreement, dated October&nbsp;1, 2015, as amended, pursuant to which Lonza Sales AG provided certain development services and manufactured clinical supplies of narsoplimab for Omeros. The new Agreement provides for the production by Lonza of commercial quantities of narsoplimab in accordance with agreed specifications for use following regulatory marketing approvals.&nbsp;</font>
		</p>
		<p style="margin:0pt;text-indent:36pt;color:#000000;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;font-family:Times New Roman,Times,serif;">&nbsp;</font>
		</p>
		<p style="margin:0pt;text-indent:36pt;color:#000000;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;">Omeros is preparing a biologics license application and a marketing authorization application for submission to the U.S. Food and Drug Administration and to the European Medicines Agency, respectively, for narsoplimab for the treatment of hematopoietic stem cell transplant-associated thrombotic microangiopathy (HSCT-TMA). Omeros also has ongoing Phase 3 clinical programs for narsoplimab in immunoglobulin A (IgA) nephropathy and in atypical hemolytic uremic syndrome (aHUS). </font>
		</p>
		<p style="margin:0pt;text-indent:36pt;color:#000000;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;font-family:Times New Roman,Times,serif;">&nbsp;</font>
		</p>
		<p style="margin:0pt;text-indent:36pt;color:#000000;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;">Under the Agreement Lonza will manufacture narsoplimab pursuant to purchase orders issued in accordance with forecasts provided by Omeros. Omeros will purchase narsoplimab that meets agreed specifications in batches, with the price per batch varying according to the total number of batches ordered for serial production in a single manufacturing campaign. Omeros is obligated to purchase a minimum number of batches annually beginning on a specified anniversary&nbsp;of the first commercial sale of narsoplimab in either the United States or European Union. Omeros may be obligated to pay certain fees to Lonza upon cancellation of purchase orders. </font>
		</p>
		<p style="margin:0pt;text-indent:36pt;color:#000000;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;">&nbsp;</font>
		</p>
		<p style="margin:0pt;text-indent:36pt;color:#000000;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;">The initial term of the Agreement expires five years after the first commercial sale of narsoplimab in either the United States or European Union, subject to automatic renewal for an additional four-year term unless Omeros provides notice of non-renewal at least three years prior to the end of the initial term. Either party may terminate the Agreement, subject to applicable notice and cure periods, (i) if regulatory marketing approval for narsoplimab cannot be obtained in either the United States or European Union, (ii) if narsoplimab is withdrawn from both the United States and European Union markets following regulatory marketing approval, (iii) for material breach of the Agreement by the other party or (iv) due to the other party&#x2019;s bankruptcy, insolvency, or dissolution. </font>
		</p>
		<p style="margin:0pt;color:#000000;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;">&nbsp;</font>
		</p>
		<p style="margin:0pt;text-indent:36pt;color:#000000;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;">The Agreement also includes customary provisions relating to, among others, insurance and indemnification, delivery and acceptance procedures, intellectual property, warranties, and confidentiality.</font>
		</p>
		<p style="margin:12pt 0pt 0pt;background-color: #FFFFFF;text-indent:36pt;color:#000000;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;">The foregoing description of the Agreement is only a summary of its material terms and does not purport to be complete. A copy of the Agreement will be filed as an exhibit to Omeros&#x2019; Quarterly Report on Form 10-Q for the quarter ending September</font><font style="display:inline;color:#000000;"> 30, 2019. Pursuant to Item 601(b)(10)(iv) of Regulation S-K, Omeros intends to </font><font style="display:inline;color:#000000;background-color: #FFFFFF;">redact from the filed copy of the Agreement certain information that is both (i) not material and (ii) would be competitively harmful if publicly disclosed</font><font style="display:inline;color:#000000;">.</font>
		</p>
		<p style="margin:0pt 0pt 12pt;text-indent:36pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;">&nbsp;</font>
		</p>
		<p style="margin:0pt;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;font-family:Times New Roman,Times,serif;font-weight:bold;"></font>
		</p>
		<p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;"></font></p></div><div style="margin-left:10.2941176470588%;margin-right:10.2941176470588%;">
		<p><font size="1"> </font></p><div style="width:100%">

		<p style="margin:24pt 0pt 0pt;text-align:center;font-family:Times New Roman,Times,serif;font-size: 10pt;">

			<font style="display:inline;">1</font>

		</p>

</div></div><div style="margin-left:10.2941176470588%;margin-right:10.2941176470588%;page-break-after:always;"><div style="background-color:#000000;clear:both;height:2pt;border:0;margin:30pt 0pt 30pt 0pt;"></div></div><div style="margin-left:10.2941176470588%;margin-right:10.2941176470588%;"></div><div style="margin-left:10.2941176470588%;margin-right:10.2941176470588%;"><p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;"><font style="display:inline;"></font>
		</p>
		<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman,Times,serif;font-weight:bold;font-size: 10pt;">
			<font style="display:inline;">SIGNATURES</font>
		</p>
		<p style="margin:0pt 0pt 12pt;text-indent:36pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;">Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.</font>
		</p>
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					<p style="margin:0pt;font-family:Times New Roman,Times,serif;height:1.00pt;overflow:hidden;font-size:0pt;">
						<font style="display:inline;font-size:1pt;">&nbsp;</font></p>
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						<font style="display:inline;font-size:1pt;">&nbsp;</font></p>
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						<font style="display:inline;font-size:1pt;">&nbsp;</font></p>
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					<p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">&nbsp;</font></p>
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				<td colspan="2" valign="bottom" style="width:49.92%;background-color: #auto;padding:0pt;">
					<p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;font-weight:bold;">OMEROS CORPORATION</font></p>
				</td>
			</tr>
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				<td valign="bottom" style="width:50.08%;background-color: #auto;padding:0pt;">
					<p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">&nbsp;</font></p>
				</td>
				<td valign="bottom" style="width:03.70%;background-color: #auto;padding:0pt;">
					<p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">&nbsp;</font></p>
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					<p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">&nbsp;</font></p>
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					<p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">Date: July 31, 2019</font></p>
				</td>
				<td valign="bottom" style="width:03.70%;background-color: #auto;padding:0pt;">
					<p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">By:</font></p>
				</td>
				<td valign="bottom" style="width:46.22%;border-bottom:1pt solid #000000 ;background-color: #auto;padding:0pt;">
					<p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">/s/ Gregory A. Demopulos</font></p>
				</td>
			</tr>
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					<p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">&nbsp;</font></p>
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					<p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">&nbsp;</font></p>
				</td>
				<td valign="bottom" style="width:46.22%;border-top:1pt solid #000000 ;background-color: #auto;padding:0pt;">
					<p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">Gregory A. Demopulos, M.D.</font></p>
				</td>
			</tr>
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				<td valign="bottom" style="width:50.08%;background-color: #auto;padding:0pt;">
					<p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">&nbsp;</font></p>
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					<p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">&nbsp;</font></p>
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					<p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">President, Chief Executive Officer and</font></p>
				</td>
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					<p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">&nbsp;</font></p>
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				<td valign="bottom" style="width:03.70%;background-color: #auto;padding:0pt;">
					<p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">&nbsp;</font></p>
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				<td valign="bottom" style="width:46.22%;background-color: #auto;padding:0pt;">
					<p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
						<font style="display:inline;">Chairman of the Board of Directors</font></p>
				</td>
			</tr>
		</table></div>
		<p style="margin:0pt;font-family:Times New Roman,Times,serif;font-size: 10pt;">
			<font style="display:inline;">&nbsp;</font>
		</p></div><div style="margin-left:10.2941176470588%;margin-right:10.2941176470588%;">
		<p><font size="1"> </font></p><div style="width:100%">

		<p style="margin:24pt 0pt 0pt;text-align:center;font-family:Times New Roman,Times,serif;font-size: 10pt;">

			<font style="display:inline;">2</font>

		</p>

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omer_Current_Folio_8K_Other
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
Date of Report (Date of earliest event reported): July 28, 2019
OMEROS CORPORATION
(Exact name of Registrant as Specified in Its Charter)
Washington
001‑34475
91‑1663741
(State or Other Jurisdiction
of Incorporation)
(Commission File Number)
(IRS Employer
Identification No.)
201 Elliott Avenue West
Seattle, Washington
98119
(Address of Principal Executive Offices) (Zip Code)
Registrant's Telephone Number, Including Area Code: (206) 676‑5000
(Former Name or Former Address, if Changed Since Last Report)
Check the appropriate box below if the Form 8‑K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):
☐
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
☐
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
☐
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
☐
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Securities Registered Pursuant to Section 12(b) of the Act:
Title of each class
Trading Symbol(s)
Name of each exchange on which registered
Common stock, $0.01 par value per share
OMER
The Nasdaq Stock Market LLC
Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 under the Securities Act of 1933 (17 CFR 230.405) or Rule 12b-2 under the Securities Exchange Act of 1934 (17 CFR 240.12b-2).
Emerging growth company
☐
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.
☐
Item 1.01    Entry Into a Material Definitive Agreement.
On July 28, 2019, Omeros Corporation ("Omeros") entered into a Master Services Agreement (the "Agreement") with Lonza Biologics Tuas Pte. Ltd. ("Lonza") for the commercial production of narsoplimab, also referred to as OMS721, Omeros' lead human monoclonal antibody targeting mannan-binding lectin-associated serine protease-2 (MASP-2). The Agreement also provides for certain regulatory support and related services to be provided by Lonza from time to time.
Omeros and Lonza Sales AG previously entered into a Master Services Agreement, dated October 1, 2015, as amended, pursuant to which Lonza Sales AG provided certain development services and manufactured clinical supplies of narsoplimab for Omeros. The new Agreement provides for the production by Lonza of commercial quantities of narsoplimab in accordance with agreed specifications for use following regulatory marketing approvals.
Omeros is preparing a biologics license application and a marketing authorization application for submission to the U.S. Food and Drug Administration and to the European Medicines Agency, respectively, for narsoplimab for the treatment of hematopoietic stem cell transplant-associated thrombotic microangiopathy (HSCT-TMA). Omeros also has ongoing Phase 3 clinical programs for narsoplimab in immunoglobulin A (IgA) nephropathy and in atypical hemolytic uremic syndrome (aHUS).
Under the Agreement Lonza will manufacture narsoplimab pursuant to purchase orders issued in accordance with forecasts provided by Omeros. Omeros will purchase narsoplimab that meets agreed specifications in batches, with the price per batch varying according to the total number of batches ordered for serial production in a single manufacturing campaign. Omeros is obligated to purchase a minimum number of batches annually beginning on a specified anniversary of the first commercial sale of narsoplimab in either the United States or European Union. Omeros may be obligated to pay certain fees to Lonza upon cancellation of purchase orders.
The initial term of the Agreement expires five years after the first commercial sale of narsoplimab in either the United States or European Union, subject to automatic renewal for an additional four-year term unless Omeros provides notice of non-renewal at least three years prior to the end of the initial term. Either party may terminate the Agreement, subject to applicable notice and cure periods, (i) if regulatory marketing approval for narsoplimab cannot be obtained in either the United States or European Union, (ii) if narsoplimab is withdrawn from both the United States and European Union markets following regulatory marketing approval, (iii) for material breach of the Agreement by the other party or (iv) due to the other party's bankruptcy, insolvency, or dissolution.
The Agreement also includes customary provisions relating to, among others, insurance and indemnification, delivery and acceptance procedures, intellectual property, warranties, and confidentiality.
The foregoing description of the Agreement is only a summary of its material terms and does not purport to be complete. A copy of the Agreement will be filed as an exhibit to Omeros' Quarterly Report on Form 10-Q for the quarter ending September
30, 2019. Pursuant to Item 601(b)(10)(iv) of Regulation S-K, Omeros intends to
redact from the filed copy of the Agreement certain information that is both (i) not material and (ii) would be competitively harmful if publicly disclosed
.
1
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
OMEROS CORPORATION
Date: July 31, 2019
By:
/s/ Gregory A. Demopulos
Gregory A. Demopulos, M.D.
President, Chief Executive Officer and
Chairman of the Board of Directors
2