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<TITLE>Form 8-K For Oragenics, Inc.</TITLE>
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<B><P ALIGN="CENTER">UNITED STATES<br>
SECURITIES AND EXCHANGE COMMISSION<br>
Washington, D.C. 20549</P></B>

<B><P ALIGN="CENTER">FORM 8-K</P></B>

<B><P ALIGN="CENTER">CURRENT REPORT<br>
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934</P></B>

<p align=left><CENTER><TABLE CELLSPACING=0 BORDER=0 CELLPADDING=0 WIDTH=680>
<TR><TD VALIGN="TOP">

<B><P ALIGN="CENTER">October 31, 2003</B></TD>
</TR>
<TR><TD VALIGN="TOP">

<P ALIGN="CENTER">Date of Report (Date of earliest event reported) </TD>
</TR>
</TABLE>
</CENTER>

<br>
<p align=left><CENTER><TABLE CELLSPACING=0 BORDER=0 CELLPADDING=0 WIDTH=680>
<TR><TD VALIGN="TOP">
<B><P ALIGN="CENTER">ORAGENICS, INC.</B></TD>
</TR>
<TR><TD VALIGN="TOP">
<P ALIGN="CENTER">(Exact name of registrant as specified in its charter)</TD>
</TR>
</TABLE>
</CENTER>

<br>
<p align=left><TABLE CELLSPACING=0 BORDER=0 CELLPADDING=0 WIDTH=680>
<TR><TD WIDTH="36%" VALIGN="TOP">

<B><P ALIGN="CENTER">Florida</B></TD>
<TD WIDTH="32%" VALIGN="TOP">

<B><P ALIGN="CENTER">333-100568</B></TD>
<TD WIDTH="32%" VALIGN="TOP">

<B><P ALIGN="CENTER">59-3410522</B></TD>
</TR>
<TR><TD WIDTH="36%" VALIGN="TOP">

<P ALIGN="CENTER">(State or other jurisdiction<br>
of incorporation)</TD>
<TD WIDTH="32%" VALIGN="TOP">

<P ALIGN="CENTER">(Commission<br>
File Number)</TD>
<TD WIDTH="32%" VALIGN="TOP">

<P ALIGN="CENTER">(IRS Employer<br>
Identification No.)</TD>
</TR>
</TABLE>
</CENTER>

<br>
<p align=left><CENTER><TABLE CELLSPACING=0 BORDER=0 CELLPADDING=0 WIDTH=680>
<TR><TD VALIGN="TOP">

<B><P ALIGN="CENTER">12085 Research Drive<br>
Alachua, Florida 32615</B></TD>
</TR>
<TR><TD VALIGN="TOP">

<P ALIGN="CENTER">(Address of principal executive offices including zip code)</TD>
</TR>
</TABLE>
</CENTER>

<br>
<p align=left><CENTER><TABLE CELLSPACING=0 BORDER=0 CELLPADDING=0 WIDTH=680>
<TR><TD VALIGN="TOP">

<B><P ALIGN="CENTER">(386) 418-4018</B></TD>
</TR>
<TR><TD VALIGN="TOP">

<P ALIGN="CENTER">Registrant's telephone number, including area code</TD>
</TR>
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<br>
<p align=left><CENTER><TABLE BORDER=0 CELLSPACING=0 CELLPADDING=0 WIDTH=680>
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<B><P ALIGN="CENTER">None</B></TD>
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<TR><TD VALIGN="TOP">

<P ALIGN="CENTER">(Former name or former address, if changed since last report.)</TD>
</TR>
</TABLE>
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<p>&nbsp;</p>
<p>&nbsp;</p>

<P>==================================================================================</P>

<p>&nbsp;</p>
<page>
<hr>

<B><P>ITEM 7. &nbsp; &nbsp; &nbsp; FINANCIAL INFORMATION AND EXHIBITS</P></B>

<P ALIGN="LEFT"><CENTER><TABLE BORDER=0 CELLSPACING=0 CELLPADDING=0 WIDTH=420>
<TR><TD WIDTH="24%" VALIGN="TOP">

<B><P>Exhibit No.<hr></B></TD>
<TD WIDTH="76%" VALIGN="TOP">
<B><P>Description<hr></B></TD>
</TR>
<TR><TD WIDTH="24%" VALIGN="TOP">
<P>99.1</TD>
<TD WIDTH="76%" VALIGN="TOP">
<P>Press Release</TD>
</TR>
</TABLE>
</CENTER></P>


<br>
<B><P>ITEM 9. &nbsp; &nbsp; &nbsp; REGULATION FD DISCLOSURE</P></B>

<P>Oragenics, Inc. announces today that it has granted stock options to Paul Hassie and Brian Anderson.</P>

<p>&nbsp;</p>
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<B><P ALIGN="CENTER">SIGNATURES</P></B>

<P>In accordance with the requirements of the Exchange Act, the registrant caused this report to be signed on its behalf by the undersigned, thereunto duly authorized on this 31<SUP>st</SUP> day of October, 2003.</P>

<DIR>
<DIR><TABLE BORDER=0 CELLSPACING=0 CELLPADDING=0 WIDTH=680>
<TR><TD WIDTH="38%" VALIGN="TOP">

<P>&nbsp;</TD>
<TD WIDTH="62%" VALIGN="TOP" COLSPAN=2>

<B><P>ORAGENICS, INC.<br>
(Registrant)</B></TD>
</TR>
<TR><TD WIDTH="38%" VALIGN="TOP">

<P>&nbsp;</TD>
<TD WIDTH="7%" VALIGN="TOP">

<P>BY:</TD>
<TD WIDTH="55%" VALIGN="TOP">

<P>/s/ Mento A. Soponis</TD>
</TR>
<TR><TD WIDTH="38%" VALIGN="TOP">

<P>&nbsp;</TD>
<TD WIDTH="7%" VALIGN="TOP">

<P>&nbsp;</TD>
<TD WIDTH="55%" VALIGN="TOP">

<P>Mento A. Soponis<br>
President, Principal Executive Officer and a member of the Board of Directors.</TD>
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</DIR>
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{"company-data": {"conformed-name": "ORAGENICS INC", "cik": "0001174940", "assigned-sic": "2834", "irs-number": "593410522", "state-of-incorporation": "FL", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "333-100568", "film-number": "03971145"}, "business-address": {"street1": "12085 RESEARCH DRIVE", "city": "ALACHUA", "state": "FL", "zip": "32615", "phone": "3864184018"}, "mail-address": {"street1": "12085 RESEARCH DRIVE", "city": "ALACHUA", "state": "FL", "zip": "32615"}}
Form 8-K For Oragenics, Inc.
===================================================================================
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
October 31, 2003
Date of Report (Date of earliest event reported)
ORAGENICS, INC.
(Exact name of registrant as specified in its charter)
Florida
333-100568
59-3410522
(State or other jurisdiction
of incorporation)
(Commission
File Number)
(IRS Employer
Identification No.)
12085 Research Drive
Alachua, Florida 32615
(Address of principal executive offices including zip code)
(386) 418-4018
Registrant's telephone number, including area code
None
(Former name or former address, if changed since last report.)
==================================================================================
ITEM 7.       FINANCIAL INFORMATION AND EXHIBITS
Exhibit No.
Description
99.1
Press Release
ITEM 9.       REGULATION FD DISCLOSURE
Oragenics, Inc. announces today that it has granted stock options to Paul Hassie and Brian Anderson.
- 2 -
SIGNATURES
In accordance with the requirements of the Exchange Act, the registrant caused this report to be signed on its behalf by the undersigned, thereunto duly authorized on this 31
st
day of October, 2003.
ORAGENICS, INC.
(Registrant)
BY:
/s/ Mento A. Soponis
Mento A. Soponis
President, Principal Executive Officer and a member of the Board of Directors.
- 3 -