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<META NAME="ClientName" CONTENT="TRIMERIS, INC.">


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<B><FONT FACE="CG Times" SIZE=2><P ALIGN="RIGHT"></P>


</FONT><P ALIGN="CENTER">UNITED STATES</P>


<P ALIGN="CENTER">SECURITIES AND EXCHANGE COMMISSION</P>


<P ALIGN="CENTER">Washington, DC 20549</P>


</B><P ALIGN="JUSTIFY"></P>


<P ALIGN="JUSTIFY">&nbsp;</P>


<B><FONT SIZE=5><P ALIGN="CENTER">FORM 8-K</P>


</B></FONT><P ALIGN="JUSTIFY"></P>


<P ALIGN="JUSTIFY">&nbsp;</P>


<B><P ALIGN="CENTER">CURRENT REPORT Pursuant</P>


<P ALIGN="CENTER">to Section 13 or 15(d) of the</P>


<P ALIGN="CENTER">Securities Exchange Act of 1934</P>


</B><P ALIGN="JUSTIFY"></P>


<P ALIGN="JUSTIFY">&nbsp;</P>


<P ALIGN="CENTER">Date of report (Date of earliest event reported)<U>&#9;July 19, 2005</P>


</U><P ALIGN="JUSTIFY"></P>


<P ALIGN="CENTER">Trimeris, Inc.</P>


<FONT SIZE=3><P ALIGN="CENTER">(Exact Name of Registrant as Specified in Its Charter)</P>


</FONT><P ALIGN="JUSTIFY"></P>


<P ALIGN="CENTER">Delaware</P>


<FONT SIZE=3><P ALIGN="CENTER">(State or Other Jurisdiction of Incorporation)</P>


</FONT><P ALIGN="JUSTIFY"></P>


<TABLE CELLSPACING=0 BORDER=0 CELLPADDING=7 WIDTH=606>


<TR><TD WIDTH="53%" VALIGN="TOP">


<P ALIGN="CENTER">0-23155</TD>


<TD WIDTH="47%" VALIGN="TOP">


<P ALIGN="CENTER">56-1808663</TD>


</TR>


<TR><TD WIDTH="53%" VALIGN="TOP">


<P ALIGN="CENTER">(Commission File Number)</TD>


<TD WIDTH="47%" VALIGN="TOP">


<P ALIGN="CENTER">(IRS Employer Identification No.)</TD>


</TR>


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<P ALIGN="CENTER"></P>


<P ALIGN="CENTER">&#9;</P>


<TABLE CELLSPACING=0 BORDER=0 CELLPADDING=7 WIDTH=630>


<TR><TD WIDTH="56%" VALIGN="TOP" HEIGHT=9>


<P ALIGN="CENTER">3500 Paramount Parkway, Morrisville, North Carolina</TD>


<TD WIDTH="44%" VALIGN="TOP" HEIGHT=9>


<P ALIGN="CENTER">27560</TD>


</TR>


<TR><TD WIDTH="56%" VALIGN="TOP">


<P ALIGN="CENTER">(Address of Principal Executive Offices)</TD>


<TD WIDTH="44%" VALIGN="TOP">


<P ALIGN="CENTER">(Zip Code)</TD>


</TR>


</TABLE>





<P ALIGN="CENTER"></P>


<P ALIGN="CENTER">&nbsp;</P>


<P ALIGN="CENTER">(919) 419-6050</P>


<FONT SIZE=3><P ALIGN="CENTER">(Registrant's Telephone Number, Including Area Code)</P>


</FONT><P ALIGN="JUSTIFY"></P>


<P ALIGN="CENTER">N/A</P>


<FONT SIZE=3><P ALIGN="CENTER">(Former Name or Former Address, if Changed Since Last Report)</P>


</FONT><P ALIGN="JUSTIFY"></P>


<P ALIGN="JUSTIFY">&#9;Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (<I>see </I>General Instruction A.2. below):</P>


<P ALIGN="JUSTIFY"></P>


<P ALIGN="JUSTIFY">&#9;<FONT FACE="Wingdings">&#111;</FONT>


&#9;Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)</P>


<P ALIGN="JUSTIFY"></P>


<P ALIGN="JUSTIFY">&#9;<FONT FACE="Wingdings">&#111;</FONT>


&#9;Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)</P>


<P ALIGN="JUSTIFY"></P>


<P ALIGN="JUSTIFY">&#9;<FONT FACE="Wingdings">&#111;</FONT>


&#9;Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))</P>


<P ALIGN="JUSTIFY"></P>


<P ALIGN="JUSTIFY">&#9;<FONT FACE="Wingdings">&#111;</FONT>


&#9;Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))</P>


<FONT FACE="CG Times" SIZE=2>


<P>&nbsp;</P>


</FONT><B><P>ITEM 2.02.&#9;<FONT FACE="Times New Roman Bold">RESULTS OF OPERATIONS AND FINANCIAL CONDITION</P>


</B></FONT>


<P>The following information is furnished pursuant to Item 2.02, &quot;Results of Operations and Financial Condition.&quot;</P>





<P>On July 19, 2005, Trimeris, Inc. issued a press release announcing results for the second quarter ending June 30, 2005.  A copy of the press release is attached hereto as Exhibit 99.1. </P>





<P>The information in this Form 8-K (including Exhibit 99.1) shall not be deemed "filed" for purposes of Section&nbsp;18 of the Securities Exchange Act of 1934 (the "Exchange Act") or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933 or the Exchange Act, except as expressly set forth by specific reference in such a filing.</P>


<FONT SIZE=2>


<P>&nbsp;</P>


</FONT><B><U><P ALIGN="CENTER">SIGNATURE</P>


</B></U>


<P>&nbsp;</P>


<P>Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.</P>





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<B><P>TRIMERIS, INC.</P>


</B>


<P>&nbsp;</P>


<P>By:<U>   /s/&#9;Steven D. Skolsky&#9;</P><DIR>





</U><P>Steven D. Skolsky</P>


<P>Chief Executive Officer </P></DIR>


</DIR>


</DIR>


</DIR>


</DIR>


</DIR>


</DIR>


</DIR>


</DIR>


</DIR>


</DIR>


</DIR>





<P>&#9;</P>





<P>&nbsp;</P>


<P>Dated July 20, 2005</P></BODY>


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UNITED STATES
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, DC 20549
FORM 8-K
CURRENT REPORT Pursuant
to Section 13 or 15(d) of the
Securities Exchange Act of 1934
Date of report (Date of earliest event reported)
July 19, 2005
Trimeris, Inc.
(Exact Name of Registrant as Specified in Its Charter)
Delaware
(State or Other Jurisdiction of Incorporation)
0-23155
56-1808663
(Commission File Number)
(IRS Employer Identification No.)
3500 Paramount Parkway, Morrisville, North Carolina
27560
(Address of Principal Executive Offices)
(Zip Code)
(919) 419-6050
(Registrant's Telephone Number, Including Area Code)
N/A
(Former Name or Former Address, if Changed Since Last Report)
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (
see
General Instruction A.2. below):
o
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
o
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
o
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
o
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
ITEM 2.02.
RESULTS OF OPERATIONS AND FINANCIAL CONDITION
The following information is furnished pursuant to Item 2.02, "Results of Operations and Financial Condition."
On July 19, 2005, Trimeris, Inc. issued a press release announcing results for the second quarter ending June 30, 2005.  A copy of the press release is attached hereto as Exhibit 99.1.
The information in this Form 8-K (including Exhibit 99.1) shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934 (the "Exchange Act") or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933 or the Exchange Act, except as expressly set forth by specific reference in such a filing.
SIGNATURE
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
TRIMERIS, INC.
By:
/s/	Steven D. Skolsky
Steven D. Skolsky
Chief Executive Officer
Dated July 20, 2005