<HTML>


<HEAD>








<TITLE> </TITLE>


<META NAME="subject" CONTENT=" ">


<META NAME="keywords" CONTENT=" ">


<META NAME="doccomm" CONTENT=" ">


<META NAME="EMAIL_OWNER_ADDRESS" CONTENT="4AAA4Lxe55UJ0C+BluNTxlY02+j11FnkjMnS10k8OKYTAlQhyhA7mYu1iw==">


<META NAME="RESPONSE_SENDER_NAME" CONTENT="sAAAE9kkUq3pEoLMl26T6ee7ghJscYzbctvMoElavDD5JaU=">


<META NAME="MAIL_MSG_ID1" CONTENT="gFAA9xAl/vizjZgqrWHl+LyTzVl9AZYwD89lt5y61mGRV5ITKA/zP5MR26I5UVVNI8mlAUH4tGcUNlaO3K8zQfRPBpDXwbE7Bv2G/4roIc2I98OYQHl4IOydg1biq6sy46OqZ80v5saILBaO3K8zQfRPBpDXwbE7Bv2G/4roIc2I98OYQHl4IOydg1biq6sy46Oqvqeu3/BflFF/ooMjsdTxnxIRz7u7lNW+vxIR5ZrV1qohDzpWOPZtu">


<META NAME="MAIL_MSG_ID2" CONTENT="GxCT0Apa4VU83xAgPZC8O8qRrVI6SvXB+2iQRBdxiW0DDIjTjWuj/rB5tvd9f0AV0K5LtDQj7AJ4sHs2A8qnwlrYP5pH7sDjQ==">


</HEAD>


<BODY LINK="#0000ff" VLINK="#800080" BGCOLOR="#ffffff">





<FONT SIZE=2>


<B><P ALIGN="CENTER">&nbsp;</P>


<P ALIGN="CENTER">UNITED STATES </P>


<P ALIGN="CENTER">SECURITIES AND EXCHANGE COMMISSION </P>


</B><P ALIGN="CENTER">Washington, D.C. 20549 </P>


<P ALIGN="JUSTIFY"></P>


<P ALIGN="CENTER">________________________</P>


<P ALIGN="CENTER"></P>


</FONT><B><FONT SIZE=4><P ALIGN="CENTER">FORM 8-K </P>


</B></FONT><FONT SIZE=2><P ALIGN="CENTER">________________________</P>


<P ALIGN="JUSTIFY"></P>


<P ALIGN="CENTER">CURRENT REPORT</P>


<P ALIGN="JUSTIFY"></P><DIR>





<P ALIGN="CENTER">Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 </P>


<P ALIGN="CENTER"></P>


<P ALIGN="CENTER">Date of report (date of earliest event reported):  January 19, 2006</P>


<P ALIGN="JUSTIFY"></P></DIR>





</FONT><B><FONT SIZE=5><P ALIGN="CENTER">CoTherix, Inc.</P>


</B></FONT><FONT SIZE=2><P ALIGN="CENTER">(Exact name of registrant as specified in its charter) </P>


<P ALIGN="CENTER"></P>


<B><P>&nbsp;</P></B></FONT>


<P ALIGN="CENTER"><CENTER><TABLE CELLSPACING=0 BORDER=0 WIDTH=716>


<TR><TD WIDTH="46%" VALIGN="TOP" HEIGHT=14><DIR>





<B><FONT SIZE=2><P>&#9;&#9;Delaware</DIR>


</B></FONT></TD>


<TD WIDTH="22%" VALIGN="TOP" HEIGHT=14>


<B><FONT SIZE=2><P ALIGN="CENTER">000-50794</B></FONT></TD>


<TD WIDTH="32%" VALIGN="BOTTOM" HEIGHT=14>


<B><FONT SIZE=2><P ALIGN="CENTER">04-3513144</B></FONT></TD>


</TR>


<TR><TD WIDTH="46%" VALIGN="TOP" HEIGHT=15><DIR>





<FONT SIZE=2><P ALIGN="CENTER">(State or other jurisdiction of incorporation or organization)</DIR>


</FONT></TD>


<TD WIDTH="22%" VALIGN="TOP" HEIGHT=15><DIR>





<FONT SIZE=2><P ALIGN="CENTER">(Commission File Number)</DIR>


</FONT></TD>


<TD WIDTH="32%" VALIGN="BOTTOM" HEIGHT=15><DIR>





<FONT SIZE=2><P ALIGN="CENTER">(I.R.S. employer identification number)</DIR>


</FONT></TD>


</TR>


</TABLE>


</CENTER></P>





<B><FONT SIZE=2>


<P ALIGN="CENTER">&nbsp;</P>


<P ALIGN="CENTER">5000 Shoreline Court, Suite 101, South San Francisco, CA 94080</P>


</B><P ALIGN="CENTER">(Address of principal executive offices and zip code) </P>


<P ALIGN="JUSTIFY"></P>


<B><P ALIGN="CENTER">(650) 808-6500 </P>


</B><P ALIGN="CENTER">(Registrant's telephone number, including area code) </P>


<P ALIGN="CENTER"></P>


<P>Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions: </P>


</FONT><FONT SIZE=1><P>&nbsp;</P></FONT>


<TABLE CELLSPACING=0 BORDER=0 WIDTH=721>


<TR><TD WIDTH="4%" VALIGN="TOP" HEIGHT=22>


<P>[ ]</TD>


<TD WIDTH="96%" VALIGN="TOP" HEIGHT=22>


<FONT SIZE=2><P>Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)</P>


<P> </FONT></TD>


</TR>


<TR><TD WIDTH="4%" VALIGN="TOP">


<P>[ ]</TD>


<TD WIDTH="96%" VALIGN="TOP">


<FONT SIZE=2><P>Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) </FONT></TD>


</TR>


</TABLE>





<FONT SIZE=1><P>&nbsp;</P></FONT>


<TABLE CELLSPACING=0 BORDER=0 WIDTH=720>


<TR><TD WIDTH="4%" VALIGN="TOP">


<P>[ ]</TD>


<TD WIDTH="96%" VALIGN="TOP">


<FONT SIZE=2><P>Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) </FONT></TD>


</TR>


</TABLE>





<FONT SIZE=1><P>&nbsp;</P></FONT>


<TABLE CELLSPACING=0 BORDER=0 WIDTH=720>


<TR><TD WIDTH="4%" VALIGN="TOP">


<P>[ ]</TD>


<TD WIDTH="96%" VALIGN="TOP">


<FONT SIZE=2><P>Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) </FONT></TD>


</TR>


</TABLE>





<FONT SIZE=2><P ALIGN="JUSTIFY"></P>


<P>&nbsp;</P>


<P ALIGN="JUSTIFY">&nbsp;</P>


<B><P ALIGN="RIGHT"><A NAME="toc"></A></P>


<P ALIGN="RIGHT">&nbsp;</P>


<P>Item 2.02.  Results of Operations and Financial Condition </P>


</B><P ALIGN="JUSTIFY">On January 19, 2006, CoTherix, Inc. issued a press release announcing certain preliminary financial results for the year ended December 31, 2005 and certain financial guidance for 2006. A copy of the press release is furnished as Exhibit 99.1 to this report.</P>


<P ALIGN="JUSTIFY"></P>


<B><P ALIGN="JUSTIFY">Item 9.01.  Financial Statements and Exhibits</P>


<P ALIGN="JUSTIFY">&nbsp;</P><DIR>


<DIR>





</B><P ALIGN="JUSTIFY">(c) Exhibits </P></DIR>





<P ALIGN="JUSTIFY">99.1  Press Release of CoTherix, Inc. dated January 19, 2006 announcing certain preliminary financial results for the year ended December 31, 2005 and certain financial guidance for 2006. The press release has been furnished in accordance with Item 2.02 of this Current Report.  </P></DIR>





<P ALIGN="JUSTIFY">The information in this Current Report (including Exhibit 99.1) is being furnished and shall not be deemed "filed" for the purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that Section. The information in this Current Report (including Exhibit 99.1) shall not be incorporated by reference into any registration statement or other document pursuant to the Securities Act of 1933, as amended, except as shall be expressly set forth by specific reference in such filing.</P>


<P ALIGN="JUSTIFY"></P>


<P ALIGN="JUSTIFY">&nbsp;</P>


<B><P ALIGN="CENTER">SIGNATURES </P>


</B><P ALIGN="JUSTIFY"></P>


<P ALIGN="JUSTIFY">Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.</P>


<P ALIGN="JUSTIFY"></P>


<P ALIGN="JUSTIFY">Date:  January 23, 2006</P></FONT>


<P ALIGN="RIGHT"><TABLE CELLSPACING=0 BORDER=0 WIDTH=288>


<TR><TD VALIGN="BOTTOM">


<B><FONT SIZE=2><P>CoTherix, Inc.</B></FONT></TD>


</TR>


<TR><TD VALIGN="TOP" HEIGHT=55>


<FONT SIZE=2><P ALIGN="JUSTIFY">By: <U>/s/ Christine E. Gray-Smith</P>


</U><P ALIGN="JUSTIFY">Christine E. Gray-Smith</P>


<P ALIGN="JUSTIFY">Executive Vice President and Chief Financial Officer</P>


</FONT></TD>


</TR>


</TABLE>


</P>





<FONT SIZE=2><P ALIGN="JUSTIFY">&nbsp;</P>


<P ALIGN="CENTER">&nbsp;</P>


<B><P ALIGN="CENTER">INDEX TO EXHIBITS FILED WITH</P>


<P ALIGN="CENTER">THE CURRENT REPORT ON FORM 8-K DATED JANUARY 19, 2006</P>


<P ALIGN="CENTER"></P>


<U><P>Exhibit</U>&#9;<U>Description</P>


</U><P>&#9;</P><DIR>


<DIR>





</B><P ALIGN="JUSTIFY">99.1&#9;Press Release of CoTherix, Inc. dated January 19, 2006 announcing certain preliminary financial results for the year ended December 31, 2005 and certain financial guidance for 2006. The press release has been furnished in accordance with Item 2.02 of this Current Report.  </P>


<P ALIGN="JUSTIFY"></P></DIR>


</DIR>


</FONT></BODY>


</HTML>
[{"type": "8-K", "sequence": "1", "filename": "rrd104598.htm", "description": "FORM 8-K", "secsgml_size_bytes": 7625}]
{"company-data": {"conformed-name": "COTHERIX INC", "cik": "0001138812", "assigned-sic": "2836", "irs-number": "043513144"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "000-50794", "film-number": "06544192"}, "business-address": {"street1": "5000 SHORELINE COURT", "street2": "SUITE 101", "city": "SOUTH SAN FRANCISCO", "state": "CA", "zip": "94080", "phone": "650-808-6500"}, "mail-address": {"street1": "5000 SHORELINE COURT", "street2": "SUITE 101", "city": "SOUTH SAN FRANCISCO", "state": "CA", "zip": "94080"}, "former-company": {"former-conformed-name": "EXHALE THERAPEUTICS INC", "date-changed": "20010503"}}
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
________________________
FORM 8-K
________________________
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
Date of report (date of earliest event reported):  January 19, 2006
CoTherix, Inc.
(Exact name of registrant as specified in its charter)
Delaware
000-50794
04-3513144
(State or other jurisdiction of incorporation or organization)
(Commission File Number)
(I.R.S. employer identification number)
5000 Shoreline Court, Suite 101, South San Francisco, CA 94080
(Address of principal executive offices and zip code)
(650) 808-6500
(Registrant's telephone number, including area code)
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
[ ]
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
[ ]
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
[ ]
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
[ ]
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Item 2.02.  Results of Operations and Financial Condition
On January 19, 2006, CoTherix, Inc. issued a press release announcing certain preliminary financial results for the year ended December 31, 2005 and certain financial guidance for 2006. A copy of the press release is furnished as Exhibit 99.1 to this report.
Item 9.01.  Financial Statements and Exhibits
(c) Exhibits
99.1  Press Release of CoTherix, Inc. dated January 19, 2006 announcing certain preliminary financial results for the year ended December 31, 2005 and certain financial guidance for 2006. The press release has been furnished in accordance with Item 2.02 of this Current Report.
The information in this Current Report (including Exhibit 99.1) is being furnished and shall not be deemed "filed" for the purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that Section. The information in this Current Report (including Exhibit 99.1) shall not be incorporated by reference into any registration statement or other document pursuant to the Securities Act of 1933, as amended, except as shall be expressly set forth by specific reference in such filing.
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
Date:  January 23, 2006
CoTherix, Inc.
By:
/s/ Christine E. Gray-Smith
Christine E. Gray-Smith
Executive Vice President and Chief Financial Officer
INDEX TO EXHIBITS FILED WITH
THE CURRENT REPORT ON FORM 8-K DATED JANUARY 19, 2006
Exhibit
Description
99.1	Press Release of CoTherix, Inc. dated January 19, 2006 announcing certain preliminary financial results for the year ended December 31, 2005 and certain financial guidance for 2006. The press release has been furnished in accordance with Item 2.02 of this Current Report.