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<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><b><font size="5" face="Times New Roman" style="font-size:18.0pt;font-weight:bold;">UNITED STATES</font></b></p>
<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><b><font size="5" face="Times New Roman" style="font-size:18.0pt;font-weight:bold;">SECURITIES AND EXCHANGE COMMISSION</font></b></p>
<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;">Washington, D.C. 20549</font></b></p>
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<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><b><font size="5" face="Times New Roman" style="font-size:18.0pt;font-weight:bold;">FORM&nbsp;8-K</font></b></p>
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<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><b><font size="3" face="Times New Roman" style="font-size:12.0pt;font-weight:bold;">CURRENT REPORT</font></b></p>
<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><b><font size="3" face="Times New Roman" style="font-size:12.0pt;font-weight:bold;">Pursuant to Section&nbsp;13 or 15(d)&nbsp;of the<br> Securities Exchange Act of 1934</font></b></p>
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<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Date of Report (Date of earliest event reported): <b>August&nbsp;29, 2013</b></font></p>
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<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><b><font size="5" face="Times New Roman" style="font-size:18.0pt;font-weight:bold;">TESARO,&nbsp;Inc.</font></b></p>
<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">(Exact name of registrant as specified in its charter)</font></p>
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<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;">Delaware</font></b></p>    </td>
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<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;">001-35587</font></b></p>    </td>
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<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;">27-2249687</font></b></p>    </td>   </tr>
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<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">(state or   other jurisdiction of incorporation)</font></p>    </td>
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<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">(Commission<br>   File Number)</font></p>    </td>
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<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">(I.R.S.   Employer<br>   Identification No.)</font></p>    </td>   </tr>  </table>
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<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;">1000   Winter Street<br>   Suite&nbsp;3300<br>   Waltham, Massachusetts</font></b></p>    </td>
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<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;">02451</font></b></p>    </td>   </tr>
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<p style="margin:0in 0in .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">&nbsp;</font></p>
<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Registrant&#146;s telephone number, including area code:&#160; <b>(339) 970-0900</b></font></p>
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<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">(Former name or former address, if changed since last report)</font></p>
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<p style="margin:0in 0in .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Check the appropriate box below if the Form&nbsp;8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):</font></p>
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<p style="margin:0in 0in .0001pt .25in;text-indent:-.25in;"><font size="2" face="Wingdings" style="font-size:10.0pt;">o</font><font size="1" style="font-size:3.0pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font><font size="2" style="font-size:10.0pt;">Written communications pursuant to Rule&nbsp;425 under the Securities Act (17 CFR 230.425)</font></p>
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<p style="margin:0in 0in .0001pt .25in;text-indent:-.25in;"><font size="2" face="Wingdings" style="font-size:10.0pt;">o</font><font size="1" style="font-size:3.0pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font><font size="2" style="font-size:10.0pt;">Soliciting material pursuant to Rule&nbsp;14a-12 under the Exchange Act (17 CFR 240.14a-12)</font></p>
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<p style="margin:0in 0in .0001pt .25in;text-indent:-.25in;"><font size="2" face="Wingdings" style="font-size:10.0pt;">o</font><font size="1" style="font-size:3.0pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font><font size="2" style="font-size:10.0pt;">Pre-commencement communications pursuant to Rule&nbsp;14d-2(b)&nbsp;under the Exchange Act (17 CFR 240.14d-2(b))</font></p>
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<p style="margin:0in 0in .0001pt .25in;text-indent:-.25in;"><font size="2" face="Wingdings" style="font-size:10.0pt;">o</font><font size="1" style="font-size:3.0pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font><font size="2" style="font-size:10.0pt;">Pre-commencement communications pursuant to Rule&nbsp;13e-4(c)&nbsp;under the Exchange Act (17 CFR 240.13e-4(c))</font></p>
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<p style="margin:0in 0in .0001pt;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;">Section&nbsp;5 &#151; Corporate Governance and Management</font></b></p>
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<p style="margin:0in 0in .0001pt;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;">Item 5.02&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; Departure of Directors or Principal Officers; Election of Directors; Appointment of Principal Officers; Compensatory Arrangements of Certain Officers</font></b></p>
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<p style="margin:0in 0in .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">(c), (e)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Compensatory Arrangements of Principal Financial Officer</font></p>
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<p style="margin:0in 0in .0001pt;text-indent:.5in;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">As previously disclosed, on July&nbsp;25, 2013, the Board of Directors of TESARO (the &#147;Company&#148;) appointed Edward C. English as the Vice President of Finance and Administration and Principal Financial Officer of the Company effective August&nbsp;31, 2013.&nbsp; In connection with Mr.&nbsp;English&#146;s appointment, on August&nbsp;29, 2013, the Compensation Committee of the Board of Directors of the Company approved an annual salary for Mr.&nbsp;English of $270,000 effective beginning on the first full pay period following the date of such approval. The Compensation Committee also granted to Mr.&nbsp;English an option to purchase 15,000 shares of common stock of the Company, pursuant to the Company&#146;s 2012 Omnibus Incentive Plan. One quarter of the option vests on August&nbsp;30, 2014, and thereafter 1/36 of the remainder vests in equal installments on each monthly anniversary of that date.</font></p>
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<p style="margin:0in 0in .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">(e)&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; Consulting Arrangements with Departing Officer</font></p>
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<p style="margin:0in 0in .0001pt;text-indent:.5in;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">As previously disclosed, on July&nbsp;25, 2013, Richard J. Rodgers, the Company&#146;s Executive Vice President, Chief Financial Officer, Treasurer and Secretary, informed the Company that he would resign all positions with the Company and its subsidiaries effective August&nbsp;31, 2013.&#160; In connection with Mr.&nbsp;Rodgers&#146; resignation, the Company and Mr.&nbsp;Rodgers have entered into a Consulting Agreement, dated as of August&nbsp;31, 2013, pursuant to which he will serve as a consultant to the Company through March&nbsp;31, 2014.&#160; Consistent with the Company&#146;s previous disclosure on July&nbsp;25, 2013, the Consulting Agreement provides that Mr.&nbsp;Rodgers will provide consulting services as requested from time to time up to 60 hours per month, that he will receive monthly compensation of $5,000 per month, and that he will receive hourly compensation of $250 per hour for services that exceed 20 hours per month.</font></p>
<p style="margin:0in 0in .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">&nbsp;</font></p>
<p style="margin:0in 0in .0001pt;text-indent:.5in;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">The Company has also entered into a Separation and Release Agreement, dated as of August&nbsp;31, 2013, with Mr.&nbsp;Rodgers, governing certain of the terms of his departure, including that&#160; Mr.&nbsp;Rodgers releases the Company of all claims or potential claims that he may have against the Company through the date of his departure.</font></p>
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<p style="margin:0in 0in .0001pt;text-indent:.5in;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">The descriptions of the Consulting Agreement and the Separation and Release Agreement with Mr.&nbsp;Rodgers are qualified by reference to those agreements, which are attached to this Current Report on Form&nbsp;8-K as Exhibits 10.1 and 10.2, respectively, and are incorporated herein by reference.</font></p>
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<p style="margin:0in 0in .0001pt;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;">Section&nbsp;9 &#151; Financial Statements and Exhibits</font></b></p>
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<p style="margin:0in 0in .0001pt;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;">Item 9.01&nbsp;&nbsp;&nbsp;Financial Statements and Exhibits.</font></b></p>
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<p style="margin:0in 0in .0001pt;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;">(d)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Exhibits</font></b></p>
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<p style="margin:0in 0in .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Consulting   Agreement, dated as of August&nbsp;31, 2013, by and between Richard J.   Rodgers and TESARO,&nbsp;Inc.</font></p>    </td>   </tr>
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<p style="margin:0in 0in .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Separation and   Release Agreement, dated as of August&nbsp;31, 2013, by and between Richard   J. Rodgers and TESARO,&nbsp;Inc.</font></p>    </td>   </tr>  </table>
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<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">2<a name="PB_2_013300_5335"></a></font></p>
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<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;">SIGNATURES</font></b></p>
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<p style="margin:0in 0in .0001pt;text-indent:.5in;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.</font></p>
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<p style="margin:0in 0in .0001pt;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;">TESARO,&nbsp;Inc.</font></b></p>    </td>   </tr>
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<p style="margin:0in 0in .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">/s/ Leon O.   Moulder,&nbsp;Jr.</font></p>    </td>   </tr>
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<p style="margin:0in 0in .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Leon O.   Moulder,&nbsp;Jr.</font></p>    </td>   </tr>
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<p style="margin:0in 0in .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Chief Executive   Officer</font></p>    </td>   </tr>  </table>
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<p style="margin:0in 0in .0001pt;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Dated:&#160; August&nbsp;30, 2013</font></p>
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<p align="center" style="margin:0in 0in .0001pt;text-align:center;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">3<a name="PB_3_013459_5796"></a></font></p>
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{"company-data": {"conformed-name": "TESARO, Inc.", "cik": "0001491576", "assigned-sic": "2834", "irs-number": "272249687", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "001-35587", "film-number": "131073114"}, "business-address": {"street1": "1000 WINTER STREET, SUITE 3300", "city": "WALTHAM", "state": "MA", "zip": "02451", "phone": "(339) 970-0900"}, "mail-address": {"street1": "1000 WINTER STREET, SUITE 3300", "city": "WALTHAM", "state": "MA", "zip": "02451"}, "former-company": {"former-conformed-name": "Tesaro, Inc.", "date-changed": "20100510"}}
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the
Securities Exchange Act of 1934
Date of Report (Date of earliest event reported):
August 29, 2013
TESARO, Inc.
(Exact name of registrant as specified in its charter)
Delaware
001-35587
27-2249687
(state or   other jurisdiction of incorporation)
(Commission
File Number)
(I.R.S.   Employer
Identification No.)
1000   Winter Street
Suite 3300
Waltham, Massachusetts
02451
(Address of   principal executive offices)
(Zip Code)
Registrant's telephone number, including area code:
(339) 970-0900
(Former name or former address, if changed since last report)
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):
o
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
o
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
o
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
o
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Section 5 — Corporate Governance and Management
Item 5.02              Departure of Directors or Principal Officers; Election of Directors; Appointment of Principal Officers; Compensatory Arrangements of Certain Officers
(c), (e)           Compensatory Arrangements of Principal Financial Officer
As previously disclosed, on July 25, 2013, the Board of Directors of TESARO (the "Company") appointed Edward C. English as the Vice President of Finance and Administration and Principal Financial Officer of the Company effective August 31, 2013.  In connection with Mr. English's appointment, on August 29, 2013, the Compensation Committee of the Board of Directors of the Company approved an annual salary for Mr. English of $270,000 effective beginning on the first full pay period following the date of such approval. The Compensation Committee also granted to Mr. English an option to purchase 15,000 shares of common stock of the Company, pursuant to the Company's 2012 Omnibus Incentive Plan. One quarter of the option vests on August 30, 2014, and thereafter 1/36 of the remainder vests in equal installments on each monthly anniversary of that date.
(e)           Consulting Arrangements with Departing Officer
As previously disclosed, on July 25, 2013, Richard J. Rodgers, the Company's Executive Vice President, Chief Financial Officer, Treasurer and Secretary, informed the Company that he would resign all positions with the Company and its subsidiaries effective August 31, 2013.  In connection with Mr. Rodgers' resignation, the Company and Mr. Rodgers have entered into a Consulting Agreement, dated as of August 31, 2013, pursuant to which he will serve as a consultant to the Company through March 31, 2014.  Consistent with the Company's previous disclosure on July 25, 2013, the Consulting Agreement provides that Mr. Rodgers will provide consulting services as requested from time to time up to 60 hours per month, that he will receive monthly compensation of $5,000 per month, and that he will receive hourly compensation of $250 per hour for services that exceed 20 hours per month.
The Company has also entered into a Separation and Release Agreement, dated as of August 31, 2013, with Mr. Rodgers, governing certain of the terms of his departure, including that  Mr. Rodgers releases the Company of all claims or potential claims that he may have against the Company through the date of his departure.
The descriptions of the Consulting Agreement and the Separation and Release Agreement with Mr. Rodgers are qualified by reference to those agreements, which are attached to this Current Report on Form 8-K as Exhibits 10.1 and 10.2, respectively, and are incorporated herein by reference.
Section 9 — Financial Statements and Exhibits
Item 9.01   Financial Statements and Exhibits.
(d)       Exhibits
10.1
Consulting   Agreement, dated as of August 31, 2013, by and between Richard J.   Rodgers and TESARO, Inc.
10.2
Separation and   Release Agreement, dated as of August 31, 2013, by and between Richard   J. Rodgers and TESARO, Inc.
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SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
TESARO, Inc.
By:
/s/ Leon O.   Moulder, Jr.
Leon O.   Moulder, Jr.
Chief Executive   Officer
Dated:  August 30, 2013
3