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  		UNITED STATES<BR>
  	SECURITIES AND EXCHANGE COMMISSION
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  	WASHINGTON, D.C. 20549
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  	FORM 8-K
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  	CURRENT REPORT
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  	Pursuant to Section&nbsp;13 or 15(d) of the Securities Exchange Act of 1934
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  	Date of Report (Date of Earliest Event Reported):
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  	&nbsp;
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  	November 14, 2007
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  	Santarus, Inc.
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  <BR>__________________________________________<BR>
  	(Exact name of registrant as specified in its charter)
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  	Delaware
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  	000-50651
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  	33-0734433
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  _____________________<BR>
  	(State or other jurisdiction
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  _____________<BR>
  	(Commission
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  ______________<BR>
  	(I.R.S. Employer
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  	of incorporation)
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  	File Number)
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  	Identification No.)
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  	&nbsp;&nbsp;
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  	10590 West Ocean Air Drive, Suite 200, San Diego, California
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  	92130
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  _________________________________<BR>
  	(Address of principal executive offices)
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  	&nbsp;
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  ___________<BR>
  	(Zip Code)
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  	Registrant&#146;s telephone number, including area code:
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  	(858) 314-5700
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  	Not Applicable
  <BR>______________________________________________<BR>
  	Former name or former address, if changed since last report
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  	&nbsp;
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  <!-- CoverPageRegistrant END --><P><FONT SIZE="2">
  Check the appropriate box below if the Form 8-K filing is intended to
  simultaneously satisfy the filing obligation of the registrant under any
  of the following provisions:</FONT>
  </P>
  <P><FONT SIZE="2">
  [&nbsp;&nbsp;]&nbsp;&nbsp;Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)<br>
  [&nbsp;&nbsp;]&nbsp;&nbsp;Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)<br>
  [&nbsp;&nbsp;]&nbsp;&nbsp;Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))<br>
  [&nbsp;&nbsp;]&nbsp;&nbsp;Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))<br>
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  <B>
  	Item 8.01 Other Events.
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  On November 14, 2007, Santarus, Inc. ("Santarus") and its licensor, the University of Missouri, received a Paragraph IV Certification Notice from Par Pharmaceutical, Inc. ("Par") advising of the submission of an Abbreviated New Drug Application ("ANDA") for omeprazole and sodium bicarbonate powder for oral suspension, 20 mg/1680 mg.<br>   <br>Par&#x2019;s certification letter sets forth allegations that U.S. Patent Nos. 5,840,737; 6,645,988; 6,489,346; 6,699,885; and 6,780,882; each of which is listed in the Orange Book for Zegerid&#174; Powder for Oral Suspension, are invalid, unenforceable and/or will not be infringed by Par&#x2019;s manufacture, use, or sale of the product for which the ANDA is submitted.  The expiration date for these patents is July 2016.<br><br>Santarus and the University of Missouri have 45 days to commence a patent infringement lawsuit against Par that would automatically stay, or bar, the U.S. Food and Drug Administration from approving Par&#x2019;s ANDA for 30 months or until a district court decision that the asserted patents are invalid, unenforceable or not infringed, whichever may occur earlier.<br><br>Santarus is evaluating the details of the Paragraph IV Certification Notice from Par and continues to have full confidence in the intellectual property protecting its Zegerid products.<br><br>Forward-Looking Statements<br><br>Santarus cautions you that statements included in this current report that are not a description of historical facts are forward-looking statements.  The inclusion of forward-looking statements should not be regarded as a representation by Santarus that any of its plans will be achieved.  Actual results may differ materially from those set forth in this report due to the risks and uncertainties inherent in Santarus&#x2019; business, including, without limitation:  the results of any proceedings related to the Paragraph IV Certification Notice from Par; Santarus&#x2019; ability to expand or maintain the scope and validity of patent protection for its Zegerid products and immediate-release technology and its ability to commercialize its Zegerid products without infringing the patent rights of others; other difficulties or delays relating to the development, testing, manufacturing and marketing of, and maintaining regulatory approvals for, Santarus&#x2019; products; and other risks detailed in Santarus&#x2019; prior press releases as well as in public periodic filings with the Securities and Exchange Commission.<br><br>You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof.  All forward-looking statements are qualified in their entirety by this cautionary statement and Santarus undertakes no obligation to revise or update this news release to reflect events or circumstances after the date hereof.  This caution is made under the safe harbor provisions of Section 21E of the Private Securities Litigation Reform Act of 1995. <br>
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  	SIGNATURES
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  	Pursuant to the requirements of the Securities Exchange Act of 1934, the
  	registrant has duly caused this report to be signed on its behalf by the
  	undersigned hereunto duly authorized.
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  	Santarus, Inc.
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  <I>
  	November 15, 2007
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  	By:
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  <I>
  	Gerald T. Proehl
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  <I>
  	Name: Gerald T. Proehl
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  	Title: President and Chief Executive Officer
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metadata_documents: [{"type": "8-K", "sequence": "1", "filename": "htm_23916.htm", "description": "LIVE FILING", "secsgml_size_bytes": 11194}]
metadata_filer: {"company-data": {"conformed-name": "SANTARUS INC", "cik": "0001172480", "assigned-sic": "2834", "irs-number": "330734433", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "000-50651", "film-number": "071251118"}, "business-address": {"street1": "10590 W OCEAN AIR DR", "street2": "STE 200", "city": "SAN DIEGO", "state": "CA", "zip": "92130", "phone": "8583145700"}, "mail-address": {"street1": "10590 W OCEAN AIR DRIVE", "street2": "STE 200", "city": "SAN DIEGO", "state": "CA", "zip": "92130"}}
text: Santarus, Inc. (Form: 8-K)
  UNITED STATES
  SECURITIES AND EXCHANGE COMMISSION
  WASHINGTON, D.C. 20549
  FORM 8-K
  CURRENT REPORT
  Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
  Date of Report (Date of Earliest Event Reported):
  November 14, 2007
  Santarus, Inc.
  __________________________________________
  (Exact name of registrant as specified in its charter)
  Delaware
  000-50651
  33-0734433
  _____________________
  (State or other jurisdiction
  _____________
  (Commission
  ______________
  (I.R.S. Employer
  of incorporation)
  File Number)
  Identification No.)
  10590 West Ocean Air Drive, Suite 200, San Diego, California
  92130
  _________________________________
  (Address of principal executive offices)
  ___________
  (Zip Code)
  Registrant's telephone number, including area code:
  (858) 314-5700
  Not Applicable
  ______________________________________________
  Former name or former address, if changed since last report
  Check the appropriate box below if the Form 8-K filing is intended to
  simultaneously satisfy the filing obligation of the registrant under any
  of the following provisions:
  [  ]  Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
  [  ]  Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
  [  ]  Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
  [  ]  Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
  Top of the Form
  Item 8.01 Other Events.
  On November 14, 2007, Santarus, Inc. ("Santarus") and its licensor, the University of Missouri, received a Paragraph IV Certification Notice from Par Pharmaceutical, Inc. ("Par") advising of the submission of an Abbreviated New Drug Application ("ANDA") for omeprazole and sodium bicarbonate powder for oral suspension, 20 mg/1680 mg.
  Par's certification letter sets forth allegations that U.S. Patent Nos. 5,840,737; 6,645,988; 6,489,346; 6,699,885; and 6,780,882; each of which is listed in the Orange Book for Zegerid® Powder for Oral Suspension, are invalid, unenforceable and/or will not be infringed by Par's manufacture, use, or sale of the product for which the ANDA is submitted.  The expiration date for these patents is July 2016.
  Santarus and the University of Missouri have 45 days to commence a patent infringement lawsuit against Par that would automatically stay, or bar, the U.S. Food and Drug Administration from approving Par's ANDA for 30 months or until a district court decision that the asserted patents are invalid, unenforceable or not infringed, whichever may occur earlier.
  Santarus is evaluating the details of the Paragraph IV Certification Notice from Par and continues to have full confidence in the intellectual property protecting its Zegerid products.
  Forward-Looking Statements
  Santarus cautions you that statements included in this current report that are not a description of historical facts are forward-looking statements.  The inclusion of forward-looking statements should not be regarded as a representation by Santarus that any of its plans will be achieved.  Actual results may differ materially from those set forth in this report due to the risks and uncertainties inherent in Santarus' business, including, without limitation:  the results of any proceedings related to the Paragraph IV Certification Notice from Par; Santarus' ability to expand or maintain the scope and validity of patent protection for its Zegerid products and immediate-release technology and its ability to commercialize its Zegerid products without infringing the patent rights of others; other difficulties or delays relating to the development, testing, manufacturing and marketing of, and maintaining regulatory approvals for, Santarus' products; and other risks detailed in Santarus' prior press releases as well as in public periodic filings with the Securities and Exchange Commission.
  You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof.  All forward-looking statements are qualified in their entirety by this cautionary statement and Santarus undertakes no obligation to revise or update this news release to reflect events or circumstances after the date hereof.  This caution is made under the safe harbor provisions of Section 21E of the Private Securities Litigation Reform Act of 1995.
  Top of the Form
  SIGNATURES
  Pursuant to the requirements of the Securities Exchange Act of 1934, the
  	registrant has duly caused this report to be signed on its behalf by the
  	undersigned hereunto duly authorized.
  Santarus, Inc.
  November 15, 2007
  By:
  Gerald T. Proehl
  Name: Gerald T. Proehl
  Title: President and Chief Executive Officer