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  <TITLE> AVALON PHARMACEUTICALS, INC. (Form: 8-K) </TITLE>
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  		UNITED STATES<BR>
  	SECURITIES AND EXCHANGE COMMISSION
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  	WASHINGTON, D.C. 20549
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  	FORM 8-K
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  	CURRENT REPORT
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  	Pursuant to Section&nbsp;13 or 15(d) of the Securities Exchange Act of 1934
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  	Date of Report (Date of Earliest Event Reported):
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  	&nbsp;
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  	June 7, 2007
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  	AVALON PHARMACEUTICALS, INC.
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  <BR>__________________________________________<BR>
  	(Exact name of registrant as specified in its charter)
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  	Delaware
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  	001-32629
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  	52-2209310
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  _____________________<BR>
  	(State or other jurisdiction
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  _____________<BR>
  	(Commission
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  ______________<BR>
  	(I.R.S. Employer
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  	of incorporation)
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  	File Number)
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  	Identification No.)
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  	20358 Seneca Meadows Parkway, Germantown, Maryland
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  	20876
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  _________________________________<BR>
  	(Address of principal executive offices)
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  	&nbsp;
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  ___________<BR>
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  	Registrant&#146;s telephone number, including area code:
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  	301-556-9900
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  	Not Applicable
  <BR>______________________________________________<BR>
  	Former name or former address, if changed since last report
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  	&nbsp;
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  <!-- CoverPageRegistrant END --><P><FONT SIZE="2">
  Check the appropriate box below if the Form 8-K filing is intended to
  simultaneously satisfy the filing obligation of the registrant under any
  of the following provisions:</FONT>
  </P>
  <P><FONT SIZE="2">
  [&nbsp;&nbsp;]&nbsp;&nbsp;Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)<br>
  [&nbsp;&nbsp;]&nbsp;&nbsp;Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)<br>
  [&nbsp;&nbsp;]&nbsp;&nbsp;Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))<br>
  [&nbsp;&nbsp;]&nbsp;&nbsp;Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))<br>
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  	Item 1.01 Entry into a Material Definitive Agreement.
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  Amendment to 2005 Omnibus Long-Term Incentive Plan<br>At the Annual Meeting of Stockholders of Avalon Pharmaceuticals, Inc.  (the "Company") held on June 7, 2007, the Company's stockholders approved an amendment to the Company's 2005 Omnibus Long-Term Incentive Plan (the "Plan") to increase the total number of shares of stock reserved for issuance under the Plan from 1,581,582 shares to 2,381,582 shares.  The amendment became effective on that date. The amendment effected no other changes to the Plan. The full text of the Plan, as amended, is filed as Exhibit 10.1 to this report and incorporated by reference herein. <br>
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  	Item 9.01 Financial Statements and Exhibits.
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  (d) .......... Exhibits<br><br>10.1 ..... Avalon Pharmaceuticals, Inc. 2005 Omnibus Long-Term Incentive Plan, as amended. <br>
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  	SIGNATURES
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  	Pursuant to the requirements of the Securities Exchange Act of 1934, the
  	registrant has duly caused this report to be signed on its behalf by the
  	undersigned hereunto duly authorized.
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  	AVALON PHARMACEUTICALS, INC.
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  	&nbsp;&nbsp;
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  <I>
  	June 7, 2007
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  	By:
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  <I>
  	/s/ Thomas G. David, Esq.
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  <I>
  	Name: Thomas G. David, Esq.
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  <I>
  	Title: General Counsel
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  	Exhibit&nbsp;Index
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  	Exhibit No.
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  	10.1
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  	&nbsp;
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  Avalon Pharmaceuticals, Inc. 2005 Omnibus Long-Term Incentive Plan, as amended.
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metadata_documents: [{"type": "8-K", "sequence": "1", "filename": "htm_20790.htm", "description": "LIVE FILING", "secsgml_size_bytes": 10452}]
metadata_filer: {"company-data": {"conformed-name": "AVALON PHARMACEUTICALS INC", "cik": "0001162192", "assigned-sic": "2834", "irs-number": "522209310", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "001-32629", "film-number": "07905664"}, "business-address": {"street1": "20358 SENECA MEADOWS PARKWAY", "city": "GERMANTOWN", "state": "MD", "zip": "20876", "phone": "3015569900"}, "mail-address": {"street1": "20358 SENECA MEADOWS PARKWAY", "city": "GERMANTOWN", "state": "MD", "zip": "20876"}}
text: AVALON PHARMACEUTICALS, INC. (Form: 8-K)
  UNITED STATES
  SECURITIES AND EXCHANGE COMMISSION
  WASHINGTON, D.C. 20549
  FORM 8-K
  CURRENT REPORT
  Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
  Date of Report (Date of Earliest Event Reported):
  June 7, 2007
  AVALON PHARMACEUTICALS, INC.
  __________________________________________
  (Exact name of registrant as specified in its charter)
  Delaware
  001-32629
  52-2209310
  _____________________
  (State or other jurisdiction
  _____________
  (Commission
  ______________
  (I.R.S. Employer
  of incorporation)
  File Number)
  Identification No.)
  20358 Seneca Meadows Parkway, Germantown, Maryland
  20876
  _________________________________
  (Address of principal executive offices)
  ___________
  (Zip Code)
  Registrant's telephone number, including area code:
  301-556-9900
  Not Applicable
  ______________________________________________
  Former name or former address, if changed since last report
  Check the appropriate box below if the Form 8-K filing is intended to
  simultaneously satisfy the filing obligation of the registrant under any
  of the following provisions:
  [  ]  Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
  [  ]  Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
  [  ]  Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
  [  ]  Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
  Top of the Form
  Item 1.01 Entry into a Material Definitive Agreement.
  Amendment to 2005 Omnibus Long-Term Incentive Plan
  At the Annual Meeting of Stockholders of Avalon Pharmaceuticals, Inc.  (the "Company") held on June 7, 2007, the Company's stockholders approved an amendment to the Company's 2005 Omnibus Long-Term Incentive Plan (the "Plan") to increase the total number of shares of stock reserved for issuance under the Plan from 1,581,582 shares to 2,381,582 shares.  The amendment became effective on that date. The amendment effected no other changes to the Plan. The full text of the Plan, as amended, is filed as Exhibit 10.1 to this report and incorporated by reference herein.
  Item 9.01 Financial Statements and Exhibits.
  (d) .......... Exhibits
  10.1 ..... Avalon Pharmaceuticals, Inc. 2005 Omnibus Long-Term Incentive Plan, as amended.
  Top of the Form
  SIGNATURES
  Pursuant to the requirements of the Securities Exchange Act of 1934, the
  	registrant has duly caused this report to be signed on its behalf by the
  	undersigned hereunto duly authorized.
  AVALON PHARMACEUTICALS, INC.
  June 7, 2007
  By:
  /s/ Thomas G. David, Esq.
  Name: Thomas G. David, Esq.
  Title: General Counsel
  Top of the Form
  Exhibit Index
  Exhibit No.
  Description
  10.1
  Avalon Pharmaceuticals, Inc. 2005 Omnibus Long-Term Incentive Plan, as amended.