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  <p align="center" style="border:none;margin:0in 0in .0001pt;padding:0in;text-align:center;text-autospace:none;"><b><font size="2" face="Times New Roman" style="letter-spacing:-.1pt;">&nbsp;</font></b></p>
  
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  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><b><font size="5" face="Times New Roman" style="font-size:18.0pt;font-weight:bold;letter-spacing:-.1pt;">UNITED STATES</font></b></p>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><b><font size="5" face="Times New Roman" style="font-size:18.0pt;font-weight:bold;letter-spacing:-.1pt;">SECURITIES AND EXCHANGE COMMISSION</font></b></p>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;letter-spacing:-.1pt;">Washington, D.C. 20549</font></b></p>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><b><font size="5" face="Times New Roman" style="font-size:18.0pt;font-weight:bold;letter-spacing:-.1pt;">FORM&nbsp;8-K</font></b></p>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><b><font size="3" face="Times New Roman" style="font-size:12.0pt;font-weight:bold;letter-spacing:-.1pt;">CURRENT REPORT</font></b></p>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><b><font size="3" face="Times New Roman" style="font-size:12.0pt;font-weight:bold;letter-spacing:-.1pt;">PURSUANT TO SECTION&nbsp;13 OR 15(d)&nbsp;OF</font></b></p>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><b><font size="3" face="Times New Roman" style="font-size:12.0pt;font-weight:bold;letter-spacing:-.1pt;">THE SECURITIES EXCHANGE ACT OF 1934</font></b></p>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;letter-spacing:-.1pt;">Date of Report (Date of earliest event
  reported) April&nbsp;24, 2008</font></b></p>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><b><font size="5" face="Times New Roman" style="font-size:18.0pt;font-weight:bold;letter-spacing:-.1pt;">MARKWEST ENERGY PARTNERS, L.P.</font></b></p>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;letter-spacing:-.1pt;">(Exact name of registrant as specified in its charter)</font></p>
  
  <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="letter-spacing:-.1pt;">&nbsp;</font></p>
  
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    <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;letter-spacing:-.1pt;">Delaware</font></b></p>
    <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;letter-spacing:-.1pt;">(State or other jurisdiction
    of</font></p>
    <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;letter-spacing:-.1pt;">incorporation or organization)</font></p>
    </td>
    <td width="2%" valign="bottom" style="padding:0in .7pt 0in .7pt;width:2.0%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><b><font size="2" face="Times New Roman" style="font-size:1.0pt;font-weight:bold;letter-spacing:-.1pt;">&nbsp;</font></b></p>
    </td>
    <td width="32%" valign="top" style="padding:0in .7pt 0in .7pt;width:32.0%;">
    <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;letter-spacing:-.1pt;">001-31239</font></b></p>
    <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;letter-spacing:-.1pt;">(Commission File Number)</font></p>
    </td>
    <td width="2%" valign="bottom" style="padding:0in .7pt 0in .7pt;width:2.0%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><b><font size="2" face="Times New Roman" style="font-size:1.0pt;font-weight:bold;letter-spacing:-.1pt;">&nbsp;</font></b></p>
    </td>
    <td width="32%" valign="top" style="padding:0in .7pt 0in .7pt;width:32.0%;">
    <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;letter-spacing:-.1pt;">27-0005456</font></b></p>
    <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;letter-spacing:-.1pt;">(I.R.S. Employer</font></p>
    <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;letter-spacing:-.1pt;">Identification Number)</font></p>
    </td>
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  <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
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    <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;letter-spacing:-.1pt;">1515 Arapahoe
    Street, Tower 2, Suite&nbsp;700, Denver CO 80202</font></b></p>
    <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;letter-spacing:-.1pt;">(Address of principal
    executive offices)</font></p>
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  <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;letter-spacing:-.1pt;">Registrant&#146;s telephone number, including area code: <b>303-925-9200</b></font></p>
  
  <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;font-weight:bold;letter-spacing:-.1pt;">Not Applicable.</font></b></p>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;letter-spacing:-.1pt;">(Former name or former address, if changed since last report.)</font></p>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
  <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;letter-spacing:-.1pt;">Check the appropriate box below
  if the Form&nbsp;8-K filing is intended to simultaneously satisfy the filing
  obligation of the registrant under any of the following provisions (see General
  Instruction A.2. below):</font></p>
  
  <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
  <p style="font-size:10.0pt;margin:0in 0in .0001pt 31.5pt;text-autospace:none;text-indent:-.25in;"><font size="2" face="Wingdings" style="font-size:10.0pt;letter-spacing:-.1pt;">o</font><font size="1" style="font-size:3.0pt;letter-spacing:-.1pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font><font style="letter-spacing:-.1pt;">Written Communications pursuant to Rule&nbsp;425
  under the Securities Act (17 CFR 230.425)</font></p>
  
  <p style="font-size:10.0pt;margin:0in 0in .0001pt 31.5pt;text-autospace:none;text-indent:-.25in;"><font size="2" face="Wingdings" style="font-size:10.0pt;letter-spacing:-.1pt;">o</font><font size="1" style="font-size:3.0pt;letter-spacing:-.1pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font><font style="letter-spacing:-.1pt;">Soliciting material pursuant to Rule&nbsp;14a-12
  under the Exchange Act (17 CFR 240.14a-12)</font></p>
  
  <p style="font-size:10.0pt;margin:0in 0in .0001pt 31.5pt;text-autospace:none;text-indent:-.25in;"><font size="2" face="Wingdings" style="font-size:10.0pt;letter-spacing:-.1pt;">o</font><font size="1" style="font-size:3.0pt;letter-spacing:-.1pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font><font style="letter-spacing:-.1pt;">Pre-Commencement communications pursuant to Rule&nbsp;14d-2(b)&nbsp;under
  the Exchange Act (17 CFR 240.14d-2(b))</font></p>
  
  <p style="font-size:10.0pt;margin:0in 0in .0001pt 31.5pt;text-autospace:none;text-indent:-.25in;"><font size="2" face="Wingdings" style="font-size:10.0pt;letter-spacing:-.1pt;">o</font><font size="1" style="font-size:3.0pt;letter-spacing:-.1pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </font><font style="letter-spacing:-.1pt;">Pre-Commencement communications pursuant to Rule&nbsp;13e-4(c)&nbsp;under
  the Exchange Act (17 CFR 240.13e-4(c))</font></p>
  
  <div style="border:none;border-bottom:double windowtext 6.0pt;padding:0in 0in 0in 0in;">
  
  <p style="border:none;margin:0in 0in .0001pt;padding:0in;text-autospace:none;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
  </div>
  
  <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
  <div style="margin:0in 0in .0001pt;text-autospace:none;"><hr size="3" width="100%" noshade color="#010101" align="left"></div>
  
  </div>
  <!-- SEQ.=1,FOLIO='',FILE='C:\JMS\jkarthi\08-13026-1\task2905318\13026-1-ba.htm',USER='105429',CD='Apr 30 14:05 2008' -->
  
  
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  <p style="font-weight:bold;margin:0in 0in .0001pt;page-break-after:avoid;text-autospace:none;"><b><font size="2" face="Times New Roman">&nbsp;</font></b></p>
  
  <p style="font-weight:bold;margin:0in 0in .0001pt;page-break-after:avoid;text-autospace:none;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;">Item 1.01&#160; Entry Into a Material Definitive Agreement</font></b></p>
  
  <p style="font-weight:bold;margin:0in 0in .0001pt;page-break-after:avoid;text-autospace:none;"><b><font size="2" face="Times New Roman">&nbsp;</font></b></p>
  
  <p style="margin:0in 0in .0001pt;text-autospace:ideograph-numeric ideograph-other;text-indent:.5in;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">On April&nbsp;24, 2008, MarkWest Energy Partners, L.P. (the &#147;Partnership&#148;)
  and its general partner, MarkWest Energy GP, L.L.C. (the &#147;General Partner&#148;), entered
  into the Second Amended and Restated Indemnification Agreements (each, a &#147;Second
  Amended Indemnification Agreement&#148;) with the directors and officers (each, an &#147;Indemnitee&#148;)
  of the General Partner.</font></p>
  
  <p style="margin:0in 0in .0001pt;text-autospace:ideograph-numeric ideograph-other;text-indent:.5in;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
  <p style="margin:0in 0in .0001pt;text-autospace:ideograph-numeric ideograph-other;text-indent:.5in;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Second Amended Indemnification Agreements were entered into with all
  directors and officers of the General Partner, including the following named
  executive officers:&nbsp; Frank Semple, President and Chief Executive Officer;
  Nancy Buese, Senior Vice President and Chief Financial Officer; Randy
  Nickerson, Senior Vice President and Chief Commercial Officer; John Mollenkopf,
  Senior Vice President and Chief Operations Officer; and C. Corwin Bromley,
  Senior Vice President, General Counsel and Secretary.&#160; The Second Amended Indemnification Agreements
  replaced indemnification agreements that were signed on October&nbsp;26, 2007
  (each, an &#147;Amended Indemnification Agreement&#148;).&#160;
  The Second Amended Indemnification Agreements clarified the relationship
  between the General Partner and the Partnership, and were in substantially the
  same form as the Amended Indemnification Agreements.</font></p>
  
  <p style="margin:0in 0in .0001pt;text-autospace:ideograph-numeric ideograph-other;text-indent:.5in;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
  <p style="margin:0in 0in .0001pt;text-autospace:ideograph-numeric ideograph-other;text-indent:.5in;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">The form of the Second Amended Indemnification Agreement provides for
  indemnification to the fullest extent permitted by law in the event the person
  was, is or becomes a party, witness or other participant in a Claim (as defined
  in the Second Amended Indemnification Agreement) by reason of (or arising in
  part out of) an Indemnification Event (as defined in the form of the Second Amended
  Indemnification Agreement).</font></p>
  
  <p style="margin:0in 0in .0001pt;text-autospace:ideograph-numeric ideograph-other;text-indent:.5in;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
  <p style="margin:0in 0in .0001pt;text-autospace:ideograph-numeric ideograph-other;text-indent:.5in;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Each Second Amended Indemnification Agreement is identical in all
  material respects. &nbsp;The description of the above-referenced Second Amended
  Indemnification Agreement does not purport to be complete and is qualified in
  its entirety by reference to the complete text of the document, which will be
  filed as an exhibit in our Form&nbsp;10-Q for the quarter ending June&nbsp;30, 2008.</font></p>
  
  <p style="margin:0in 0in .0001pt;text-autospace:ideograph-numeric ideograph-other;text-indent:.5in;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
  <p style="margin:0in 0in .0001pt .5in;text-autospace:none;"><i><font size="2" face="Times New Roman" style="font-size:10.0pt;font-style:italic;">Cautionary Statements</font></i></p>
  
  <p style="margin:0in 0in .0001pt .5in;text-autospace:none;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
  <p style="margin:0in 0in .0001pt;text-autospace:none;text-indent:.5in;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">MarkWest
  Energy Partners, L.P. is a growth-oriented master limited partnership engaged
  in the gathering, transportation, and processing of natural gas; the
  transportation, fractionation, marketing, and storage of natural gas liquids;
  and the gathering and transportation of crude oil. MarkWest has extensive
  natural gas gathering, processing, and transmission operations in the
  southwestern and Gulf Coast regions of the United States and is the largest
  natural gas processor in the Appalachian region. The primary business strategy
  of MarkWest is to provide outstanding customer service at competitive rates and
  to expand its assets and cash flow available for distribution through a
  balanced combination of organic growth projects and selective acquisitions.</font></p>
  
  <p style="margin:0in 0in .0001pt;text-autospace:none;text-indent:.5in;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
  <p style="margin:0in 0in .0001pt;text-autospace:none;text-indent:.5in;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">This
  filing may include &#147;forward-looking statements.&#148; All statements other than
  statements of historical facts included or incorporated herein may constitute forward-looking
  statements. Actual results could vary significantly from those expressed or
  implied in such statements and are subject to a number of risks and
  uncertainties. Although we believe that the expectations reflected in the
  forward-looking statements are reasonable, we can give no assurance that such
  expectations will prove to be correct. The forward-looking statements involve
  risks and uncertainties that affect our operations, financial performance, and
  other factors as discussed in our filings with the Securities and Exchange
  Commission. Among the factors that could cause results to differ materially are
  those risks discussed in our Annual Report on Form&nbsp;10-K for the year ended
  December&nbsp;31, 2007, as filed with the SEC. You are urged to carefully review
  and consider the cautionary statements and other disclosures made in those
  filings, specifically those under the heading &#147;Risk Factors.&#148; We do not
  undertake any duty to update any forward-looking statement except as required
  by law.</font></p>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">2</font></p>
  
  <div style="margin:0in 0in .0001pt;text-autospace:none;"><hr size="3" width="100%" noshade color="#010101" align="left"></div>
  
  </div>
  <!-- SEQ.=1,FOLIO='2',FILE='C:\JMS\jkarthi\08-13026-1\task2905318\13026-1-ba.htm',USER='105429',CD='Apr 30 14:05 2008' -->
  
  
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  <h3 style="font-weight:bold;letter-spacing:-.1pt;line-height:normal;margin:0in 0in .0001pt;page-break-after:avoid;text-align:center;text-autospace:none;"><b><font size="2" face="Times New Roman">&nbsp;</font></b></h3>
  
  <h3 style="font-weight:bold;letter-spacing:-.1pt;line-height:normal;margin:0in 0in .0001pt;page-break-after:avoid;text-align:center;text-autospace:none;"><b><font size="2" face="Times New Roman" style="font-size:10.0pt;">SIGNATURE</font></b></h3>
  
  <h3 style="font-weight:bold;letter-spacing:-.1pt;line-height:normal;margin:0in 0in .0001pt;page-break-after:avoid;text-align:center;text-autospace:none;"><b><font size="2" face="Times New Roman">&nbsp;</font></b></h3>
  
  <p style="margin:0in 0in .0001pt;text-autospace:none;text-indent:.5in;"><font size="2" face="Times New Roman" style="font-size:10.0pt;letter-spacing:-.1pt;">Pursuant to the requirements of
  the Securities and Exchange Act of 1934, the Registrant has duly caused this
  report to be signed on its behalf by the undersigned, thereunto duly
  authorized.</font></p>
  
  <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
  <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
  <table border="0" cellspacing="0" cellpadding="0" width="100%" style="border-collapse:collapse;width:100.0%;">
   <tr>
    <td width="6%" valign="top" style="padding:0in 0in 0in 0in;width:6.0%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
    </td>
    <td width="51%" valign="top" style="padding:0in 0in 0in 0in;width:51.34%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
    </td>
    <td width="42%" colspan="2" valign="top" style="padding:0in 0in 0in 0in;width:42.66%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">MARKWEST ENERGY PARTNERS, L.P.</font></p>
    </td>
   </tr>
   <tr>
    <td width="6%" valign="top" style="padding:0in 0in 0in 0in;width:6.0%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
    </td>
    <td width="51%" valign="top" style="padding:0in 0in 0in 0in;width:51.34%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
    </td>
    <td width="3%" valign="top" style="padding:0in 0in 0in 0in;width:3.32%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
    </td>
    <td width="39%" valign="top" style="padding:0in 0in 0in 0in;width:39.34%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">(Registrant)</font></p>
    </td>
   </tr>
   <tr>
    <td width="6%" valign="top" style="padding:0in 0in 0in 0in;width:6.0%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">&nbsp;</font></p>
    </td>
    <td width="51%" valign="top" style="padding:0in 0in 0in 0in;width:51.34%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">&nbsp;</font></p>
    </td>
    <td width="42%" colspan="2" valign="top" style="padding:0in 0in 0in 0in;width:42.66%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">&nbsp;</font></p>
    </td>
   </tr>
   <tr>
    <td width="6%" valign="top" style="padding:0in 0in 0in 0in;width:6.0%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
    </td>
    <td width="51%" valign="top" style="padding:0in 0in 0in 0in;width:51.34%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
    </td>
    <td width="3%" valign="top" style="padding:0in 0in 0in 0in;width:3.32%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">By:</font></p>
    </td>
    <td width="39%" valign="top" style="padding:0in 0in 0in 0in;width:39.34%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">MarkWest Energy GP, L.L.C.,</font></p>
    </td>
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    <td width="6%" valign="top" style="padding:0in 0in 0in 0in;width:6.0%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
    </td>
    <td width="51%" valign="top" style="padding:0in 0in 0in 0in;width:51.34%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
    </td>
    <td width="3%" valign="top" style="padding:0in 0in 0in 0in;width:3.32%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
    </td>
    <td width="39%" valign="top" style="padding:0in 0in 0in 0in;width:39.34%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Its General Partner</font></p>
    </td>
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    <td width="6%" valign="top" style="padding:0in 0in 0in 0in;width:6.0%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">&nbsp;</font></p>
    </td>
    <td width="51%" valign="top" style="padding:0in 0in 0in 0in;width:51.34%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">&nbsp;</font></p>
    </td>
    <td width="42%" colspan="2" valign="top" style="padding:0in 0in 0in 0in;width:42.66%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">&nbsp;</font></p>
    </td>
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    <td width="6%" valign="top" style="padding:0in 0in 0in 0in;width:6.0%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Date:</font></p>
    </td>
    <td width="51%" valign="top" style="padding:0in 0in 0in 0in;width:51.34%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">April&nbsp;30, 2008</font></p>
    </td>
    <td width="3%" valign="top" style="padding:0in 0in 0in 0in;width:3.32%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">By:</font></p>
    </td>
    <td width="39%" valign="top" style="border:none;border-bottom:solid windowtext 1.0pt;padding:0in 0in 0in 0in;width:39.34%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">&nbsp;&nbsp;&nbsp;/s/ NANCY K. BUESE</font></p>
    </td>
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    <td width="6%" valign="top" style="padding:0in 0in 0in 0in;width:6.0%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
    </td>
    <td width="51%" valign="top" style="padding:0in 0in 0in 0in;width:51.34%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
    </td>
    <td width="3%" valign="top" style="padding:0in 0in 0in 0in;width:3.32%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
    </td>
    <td width="39%" valign="top" style="border:none;padding:0in 0in 0in 0in;width:39.34%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Nancy K. Buese</font></p>
    </td>
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    <td width="6%" valign="top" style="padding:0in 0in 0in 0in;width:6.0%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
    </td>
    <td width="51%" valign="top" style="padding:0in 0in 0in 0in;width:51.34%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
    </td>
    <td width="3%" valign="top" style="padding:0in 0in 0in 0in;width:3.32%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:1.0pt;">&nbsp;</font></p>
    </td>
    <td width="39%" valign="top" style="padding:0in 0in 0in 0in;width:39.34%;">
    <p style="margin:0in 0in .0001pt;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">Senior Vice President and Chief Financial Officer</font></p>
    </td>
   </tr>
  </table>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><font size="2" face="Times New Roman">&nbsp;</font></p>
  
  <p align="center" style="margin:0in 0in .0001pt;text-align:center;text-autospace:none;"><font size="2" face="Times New Roman" style="font-size:10.0pt;">3</font></p>
  
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text: UNITED STATES
  SECURITIES AND EXCHANGE COMMISSION
  Washington, D.C. 20549
  FORM 8-K
  CURRENT REPORT
  PURSUANT TO SECTION 13 OR 15(d) OF
  THE SECURITIES EXCHANGE ACT OF 1934
  Date of Report (Date of earliest event
  reported) April 24, 2008
  MARKWEST ENERGY PARTNERS, L.P.
  (Exact name of registrant as specified in its charter)
  Delaware
  (State or other jurisdiction
    of
  incorporation or organization)
  001-31239
  (Commission File Number)
  27-0005456
  (I.R.S. Employer
  Identification Number)
  1515 Arapahoe
    Street, Tower 2, Suite 700, Denver CO 80202
  (Address of principal
    executive offices)
  Registrant's telephone number, including area code:
  303-925-9200
  Not Applicable.
  (Former name or former address, if changed since last report.)
  Check the appropriate box below
  if the Form 8-K filing is intended to simultaneously satisfy the filing
  obligation of the registrant under any of the following provisions (see General
  Instruction A.2. below):
  o
  Written Communications pursuant to Rule 425
  under the Securities Act (17 CFR 230.425)
  o
  Soliciting material pursuant to Rule 14a-12
  under the Exchange Act (17 CFR 240.14a-12)
  o
  Pre-Commencement communications pursuant to Rule 14d-2(b) under
  the Exchange Act (17 CFR 240.14d-2(b))
  o
  Pre-Commencement communications pursuant to Rule 13e-4(c) under
  the Exchange Act (17 CFR 240.13e-4(c))
  Item 1.01  Entry Into a Material Definitive Agreement
  On April 24, 2008, MarkWest Energy Partners, L.P. (the "Partnership")
  and its general partner, MarkWest Energy GP, L.L.C. (the "General Partner"), entered
  into the Second Amended and Restated Indemnification Agreements (each, a "Second
  Amended Indemnification Agreement") with the directors and officers (each, an "Indemnitee")
  of the General Partner.
  Second Amended Indemnification Agreements were entered into with all
  directors and officers of the General Partner, including the following named
  executive officers:  Frank Semple, President and Chief Executive Officer;
  Nancy Buese, Senior Vice President and Chief Financial Officer; Randy
  Nickerson, Senior Vice President and Chief Commercial Officer; John Mollenkopf,
  Senior Vice President and Chief Operations Officer; and C. Corwin Bromley,
  Senior Vice President, General Counsel and Secretary.  The Second Amended Indemnification Agreements
  replaced indemnification agreements that were signed on October 26, 2007
  (each, an "Amended Indemnification Agreement"). 
  The Second Amended Indemnification Agreements clarified the relationship
  between the General Partner and the Partnership, and were in substantially the
  same form as the Amended Indemnification Agreements.
  The form of the Second Amended Indemnification Agreement provides for
  indemnification to the fullest extent permitted by law in the event the person
  was, is or becomes a party, witness or other participant in a Claim (as defined
  in the Second Amended Indemnification Agreement) by reason of (or arising in
  part out of) an Indemnification Event (as defined in the form of the Second Amended
  Indemnification Agreement).
  Each Second Amended Indemnification Agreement is identical in all
  material respects.  The description of the above-referenced Second Amended
  Indemnification Agreement does not purport to be complete and is qualified in
  its entirety by reference to the complete text of the document, which will be
  filed as an exhibit in our Form 10-Q for the quarter ending June 30, 2008.
  Cautionary Statements
  MarkWest
  Energy Partners, L.P. is a growth-oriented master limited partnership engaged
  in the gathering, transportation, and processing of natural gas; the
  transportation, fractionation, marketing, and storage of natural gas liquids;
  and the gathering and transportation of crude oil. MarkWest has extensive
  natural gas gathering, processing, and transmission operations in the
  southwestern and Gulf Coast regions of the United States and is the largest
  natural gas processor in the Appalachian region. The primary business strategy
  of MarkWest is to provide outstanding customer service at competitive rates and
  to expand its assets and cash flow available for distribution through a
  balanced combination of organic growth projects and selective acquisitions.
  This
  filing may include "forward-looking statements." All statements other than
  statements of historical facts included or incorporated herein may constitute forward-looking
  statements. Actual results could vary significantly from those expressed or
  implied in such statements and are subject to a number of risks and
  uncertainties. Although we believe that the expectations reflected in the
  forward-looking statements are reasonable, we can give no assurance that such
  expectations will prove to be correct. The forward-looking statements involve
  risks and uncertainties that affect our operations, financial performance, and
  other factors as discussed in our filings with the Securities and Exchange
  Commission. Among the factors that could cause results to differ materially are
  those risks discussed in our Annual Report on Form 10-K for the year ended
  December 31, 2007, as filed with the SEC. You are urged to carefully review
  and consider the cautionary statements and other disclosures made in those
  filings, specifically those under the heading "Risk Factors." We do not
  undertake any duty to update any forward-looking statement except as required
  by law.
  2
  SIGNATURE
  Pursuant to the requirements of
  the Securities and Exchange Act of 1934, the Registrant has duly caused this
  report to be signed on its behalf by the undersigned, thereunto duly
  authorized.
  MARKWEST ENERGY PARTNERS, L.P.
  (Registrant)
  By:
  MarkWest Energy GP, L.L.C.,
  Its General Partner
  Date:
  April 30, 2008
  By:
  /s/ NANCY K. BUESE
  Nancy K. Buese
  Senior Vice President and Chief Financial Officer
  3