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  		UNITED STATES<BR>
  	SECURITIES AND EXCHANGE COMMISSION
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  	WASHINGTON, D.C. 20549
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  	FORM 8-K
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  	CURRENT REPORT
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  	Pursuant to Section&nbsp;13 or 15(d) of the Securities Exchange Act of 1934
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  	Date of Report (Date of Earliest Event Reported):
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  	&nbsp;
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  	May 22, 2006
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  	Santarus, Inc.
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  <BR>__________________________________________<BR>
  	(Exact name of registrant as specified in its charter)
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  	Delaware
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  	000-50651
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  	33-0734433
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  _____________________<BR>
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  	of incorporation)
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  	File Number)
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  	Identification No.)
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  	10590 West Ocean Air Drive, Suite 200, San Diego, California
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  	92130
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  _________________________________<BR>
  	(Address of principal executive offices)
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  ___________<BR>
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  	Registrant&#146;s telephone number, including area code:
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  	(858) 314-5700
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  	Not Applicable
  <BR>______________________________________________<BR>
  	Former name or former address, if changed since last report
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  	&nbsp;
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  <!-- CoverPageRegistrant END --><P><FONT SIZE="2">
  Check the appropriate box below if the Form 8-K filing is intended to
  simultaneously satisfy the filing obligation of the registrant under any
  of the following provisions:</FONT>
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  [&nbsp;&nbsp;]&nbsp;&nbsp;Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)<br>
  [&nbsp;&nbsp;]&nbsp;&nbsp;Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)<br>
  [&nbsp;&nbsp;]&nbsp;&nbsp;Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))<br>
  [&nbsp;&nbsp;]&nbsp;&nbsp;Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))<br>
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  	Item 7.01 Regulation FD Disclosure.
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  Gerald T. Proehl, President and Chief Executive Officer of Santarus, Inc. (the "Company") and other members of the Company&#x2019;s senior management, will be providing information about the Company in connection with meetings with retail brokers to be held in Pasadena, California on May 23, 2006.  The information provided will include a general overview of the Company and updated prescription data for the Company&#x2019;s Zegerid&#174; products for the month ended April 30, 2006, the first full month of prescription data following the launch of Zegerid Capsules.  As reported by independent market research firm IMS Health for the month ended April 30, 2006, total prescriptions for the Zegerid brand were 22,829, consisting of 8,154 prescriptions for Zegerid Capsules and 14,675 prescriptions for Zegerid Powder for Oral Suspension.  Of the total Zegerid brand prescriptions reported for the month ended April 30, 2006, 15,195 were new prescriptions.  A copy of the Company overview slides is available at the Investor Relations section of the Company's Web site at www.santarus.com, and the slides will be archived on the Web site and available for 14 days.<br><br>The information in this Current Report on Form 8-K, including the presentation slides referenced herein, is being furnished pursuant to this Item 7.01 and shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liabilities of that section, and it shall not be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or under the Exchange Act, whether made before or after the date hereof, except as expressly set forth by specific reference in such filing to this Current Report on Form 8-K. <br><br>By filing this Current Report on Form 8-K and furnishing this information, the Company makes no admission as to the materiality of any information in this report. The information contained herein and in the referenced presentation slides is summary information that is intended to be considered in the context of the Company&#x2019;s filings with the Securities and Exchange Commission (the "SEC") and other public announcements that the Company makes, by press release or otherwise, from time to time. The Company undertakes no duty or obligation to publicly update or revise the information contained in this report, although it may do so from time to time as its management believes is appropriate. Any such updating may be made through the filing of other reports or documents with the SEC, through press releases or through other public disclosure. <br>
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  	SIGNATURES
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  	Pursuant to the requirements of the Securities Exchange Act of 1934, the
  	registrant has duly caused this report to be signed on its behalf by the
  	undersigned hereunto duly authorized.
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  	Santarus, Inc.
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  <I>
  	May 22, 2006
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  <I>
  	Gerald T. Proehl
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  	Name: Gerald T. Proehl
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  	Title: President and Chief Executive Officer
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metadata_filer: {"company-data": {"conformed-name": "SANTARUS INC", "cik": "0001172480", "assigned-sic": "2834", "irs-number": "330734433", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "000-50651", "film-number": "06859270"}, "business-address": {"street1": "10590 W OCEAN AIR DR", "street2": "STE 200", "city": "SAN DIEGO", "state": "CA", "zip": "92130", "phone": "8583145700"}, "mail-address": {"street1": "10590 W OCEAN AIR DRIVE", "street2": "STE 200", "city": "SAN DIEGO", "state": "CA", "zip": "92130"}}
text: Santarus, Inc. (Form: 8-K)
  UNITED STATES
  SECURITIES AND EXCHANGE COMMISSION
  WASHINGTON, D.C. 20549
  FORM 8-K
  CURRENT REPORT
  Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
  Date of Report (Date of Earliest Event Reported):
  May 22, 2006
  Santarus, Inc.
  __________________________________________
  (Exact name of registrant as specified in its charter)
  Delaware
  000-50651
  33-0734433
  _____________________
  (State or other jurisdiction
  _____________
  (Commission
  ______________
  (I.R.S. Employer
  of incorporation)
  File Number)
  Identification No.)
  10590 West Ocean Air Drive, Suite 200, San Diego, California
  92130
  _________________________________
  (Address of principal executive offices)
  ___________
  (Zip Code)
  Registrant's telephone number, including area code:
  (858) 314-5700
  Not Applicable
  ______________________________________________
  Former name or former address, if changed since last report
  Check the appropriate box below if the Form 8-K filing is intended to
  simultaneously satisfy the filing obligation of the registrant under any
  of the following provisions:
  [  ]  Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
  [  ]  Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
  [  ]  Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
  [  ]  Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
  Top of the Form
  Item 7.01 Regulation FD Disclosure.
  Gerald T. Proehl, President and Chief Executive Officer of Santarus, Inc. (the "Company") and other members of the Company's senior management, will be providing information about the Company in connection with meetings with retail brokers to be held in Pasadena, California on May 23, 2006.  The information provided will include a general overview of the Company and updated prescription data for the Company's Zegerid® products for the month ended April 30, 2006, the first full month of prescription data following the launch of Zegerid Capsules.  As reported by independent market research firm IMS Health for the month ended April 30, 2006, total prescriptions for the Zegerid brand were 22,829, consisting of 8,154 prescriptions for Zegerid Capsules and 14,675 prescriptions for Zegerid Powder for Oral Suspension.  Of the total Zegerid brand prescriptions reported for the month ended April 30, 2006, 15,195 were new prescriptions.  A copy of the Company overview slides is available at the Investor Relations section of the Company's Web site at www.santarus.com, and the slides will be archived on the Web site and available for 14 days.
  The information in this Current Report on Form 8-K, including the presentation slides referenced herein, is being furnished pursuant to this Item 7.01 and shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liabilities of that section, and it shall not be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or under the Exchange Act, whether made before or after the date hereof, except as expressly set forth by specific reference in such filing to this Current Report on Form 8-K.
  By filing this Current Report on Form 8-K and furnishing this information, the Company makes no admission as to the materiality of any information in this report. The information contained herein and in the referenced presentation slides is summary information that is intended to be considered in the context of the Company's filings with the Securities and Exchange Commission (the "SEC") and other public announcements that the Company makes, by press release or otherwise, from time to time. The Company undertakes no duty or obligation to publicly update or revise the information contained in this report, although it may do so from time to time as its management believes is appropriate. Any such updating may be made through the filing of other reports or documents with the SEC, through press releases or through other public disclosure.
  Top of the Form
  SIGNATURES
  Pursuant to the requirements of the Securities Exchange Act of 1934, the
  	registrant has duly caused this report to be signed on its behalf by the
  	undersigned hereunto duly authorized.
  Santarus, Inc.
  May 22, 2006
  By:
  Gerald T. Proehl
  Name: Gerald T. Proehl
  Title: President and Chief Executive Officer