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<P align="center" style="font-size: 14pt"><B>UNITED STATES<BR>
SECURITIES AND EXCHANGE COMMISSION<BR>
<FONT style="font-size: 12pt">Washington, D.C. 20549
</FONT></B>

<P align="center" style="font-size: 18pt"><B>FORM 8-K</B>

<P align="center" style="font-size: 12pt"><B>CURRENT REPORT<BR>
Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934</B>

<P align="center" style="font-size: 10pt"><B>Date of Report (Date of earliest event reported): October 28, 2008</B>

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<P align="center" style="font-size: 24pt"><B>TOMOTHERAPY INCORPORATED<BR></B>
<FONT style="font-size: 10pt">(Exact name of registrant as specified in its charter)
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    <TD style="border-bottom: 1px solid #000000"><B>Wisconsin</B></TD>
    <TD>&nbsp;</TD>
    <TD style="border-bottom: 1px solid #000000"><B>001-33452</B></TD>
    <TD>&nbsp;</TD>
    <TD style="border-bottom: 1px solid #000000"><B>39-1914727</B></TD>
</TR>
<TR valign="top">
    <TD>(State or other Jurisdiction of Incorporation)</TD>
    <TD>&nbsp;</TD>
    <TD>(Commission File Number)</TD>
    <TD>&nbsp;</TD>
    <TD>(IRS Employer Identification No.)</TD>
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    <TD width="49%">&nbsp;</TD>
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    <TD style="border-bottom: 1px solid #000000"><B>1240 Deming Way<BR>Madison, Wisconsin<BR></B></TD>
    <TD>&nbsp;</TD>
    <TD style="border-bottom: 1px solid #000000"><B>53717</B></TD>
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<TR valign="top">
    <TD>(Address of Principal Executive Offices)</TD>
    <TD>&nbsp;</TD>
    <TD>(Zip Code)</TD>
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<P align="center" style="font-size: 10pt">Registrant&#146;s telephone number, including area code: <B>(608) 824-2800</B>


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    <TD nowrap>(Former name or former address if changed since last report.)</TD>
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<P align="left" style="font-size: 10pt">Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant
under any of the following provisions:

<P align="left" style="font-size: 10pt">
<FONT face="Wingdings">&#111;</FONT> Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)<BR><BR>
<FONT face="Wingdings">&#111;</FONT> Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)<BR><BR>
<FONT face="Wingdings">&#111;</FONT> Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))<BR><BR>
<FONT face="Wingdings">&#111;</FONT> Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))<BR>


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<P align="left" style="font-size: 10pt"><B>Item&nbsp;2.02. Results of Operations and Financial Condition.</B>


<P align="left" style="font-size: 10pt">On October&nbsp;28, 2008, TomoTherapy Incorporated (the &#147;Company&#148;) issued a press release announcing its financial results
for the quarter ended September&nbsp;30, 2008.&nbsp; A copy of the Company&#146;s press release dated October&nbsp;28, 2008, titled
&#147;TomoTherapy Reports Third Quarter Financial Results&#148; is attached hereto as Exhibit&nbsp;99.1.


<P align="left" style="font-size: 10pt">Exhibit&nbsp;99.1 contains forward-looking statements within the meaning of the federal securities laws. These statements
are present expectations, and are subject to the limitations listed therein and in the Company&#146;s other reports filed
with the Securities and Exchange Commission, including that actual events or results may differ materially from those
in the forward-looking statements.


<P align="left" style="font-size: 10pt">The foregoing information (including the exhibit hereto) is being furnished under &#147;Item&nbsp;2.02 Results of Operations and
Financial Condition&#148; (including the exhibit hereto) and shall not be deemed &#147;filed&#148; for purposes of Section&nbsp;18 of the
Securities Exchange Act of 1934, as amended, nor shall it be deemed incorporated by reference in any filing under the
Securities Act of 1933, as amended, except as shall be expressly set forth by specific reference in such filing.


<P align="left" style="font-size: 10pt"><B>Item&nbsp;9.01. Financial Statements and Exhibits.</B>


<P align="left" style="font-size: 10pt; text-indent: 3%">(d)&nbsp;Exhibits.

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    <TD>&nbsp;</TD>
    <TD nowrap align="center" style="border-bottom: 1px solid #000000"><B>Description</B></TD>
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    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">99.1
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Press Release dated October&nbsp;28, 2008, titled &#147;TomoTherapy Reports Third Quarter Financial Results&#148;</TD>
</TR>
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<P align="center" style="font-size: 10pt; display: none">2
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<P align="center" style="font-size: 10pt"><B>SIGNATURES</B>



<P align="left" style="font-size: 10pt; text-indent: 2%">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this
report to be signed on its behalf by the undersigned hereunto duly authorized.

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    <TD>&nbsp;</TD>
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    <TD nowrap align="center"><B>&nbsp;</B></TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center"><B>TOMOTHERAPY INCORPORATED</B></TD>
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    <TD nowrap align="left">&nbsp;</TD>
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    <TD nowrap align="center"><B>&nbsp;</B></TD>
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    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Dated: October&nbsp;28, 2008
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">By:
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">/s/ Stephen C. Hathaway</TD>
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&nbsp;</DIV></TD>
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    <TD nowrap align="left" valign="top" style="border-top: 1px solid #000000">&nbsp;</TD>
</TR>
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    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">Stephen C. Hathaway
<I>Chief Financial Officer</I></TD>
</TR>
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&nbsp;
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<P align="center" style="font-size: 10pt; display: none">3
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<P align="center" style="font-size: 10pt"><B>EXHIBIT INDEX</B>


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    <TD nowrap align="left" style="border-bottom: 1px solid #000000"><B>Number</B></TD>
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    <TD nowrap align="center" style="border-bottom: 1px solid #000000"><B>Description</B></TD>
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    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">99.1
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Press Release dated October&nbsp;28, 2008, titled &#147;TomoTherapy Reports Third Quarter Financial Results&#148;</TD>
</TR>
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<P align="center" style="font-size: 10pt; display: none">4




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Filed by Bowne Pure Compliance
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934
Date of Report (Date of earliest event reported): October 28, 2008
TOMOTHERAPY INCORPORATED
(Exact name of registrant as specified in its charter)
Wisconsin
001-33452
39-1914727
(State or other Jurisdiction of Incorporation)
(Commission File Number)
(IRS Employer Identification No.)
1240 Deming Way
Madison, Wisconsin
53717
(Address of Principal Executive Offices)
(Zip Code)
Registrant's telephone number, including area code:
(608) 824-2800
(Former name or former address if changed since last report.)
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant
under any of the following provisions:
o
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
o
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
o
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
o
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Item 2.02. Results of Operations and Financial Condition.
On October 28, 2008, TomoTherapy Incorporated (the "Company") issued a press release announcing its financial results
for the quarter ended September 30, 2008.  A copy of the Company's press release dated October 28, 2008, titled
"TomoTherapy Reports Third Quarter Financial Results" is attached hereto as Exhibit 99.1.
Exhibit 99.1 contains forward-looking statements within the meaning of the federal securities laws. These statements
are present expectations, and are subject to the limitations listed therein and in the Company's other reports filed
with the Securities and Exchange Commission, including that actual events or results may differ materially from those
in the forward-looking statements.
The foregoing information (including the exhibit hereto) is being furnished under "Item 2.02 Results of Operations and
Financial Condition" (including the exhibit hereto) and shall not be deemed "filed" for purposes of Section 18 of the
Securities Exchange Act of 1934, as amended, nor shall it be deemed incorporated by reference in any filing under the
Securities Act of 1933, as amended, except as shall be expressly set forth by specific reference in such filing.
Item 9.01. Financial Statements and Exhibits.
(d) Exhibits.
Number
Description
99.1
Press Release dated October 28, 2008, titled "TomoTherapy Reports Third Quarter Financial Results"
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this
report to be signed on its behalf by the undersigned hereunto duly authorized.
TOMOTHERAPY INCORPORATED
Dated: October 28, 2008
By:
/s/ Stephen C. Hathaway
Stephen C. Hathaway
Chief Financial Officer
EXHIBIT INDEX
Number
Description
99.1
Press Release dated October 28, 2008, titled "TomoTherapy Reports Third Quarter Financial Results"