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<P align="center" style="font-size: 14pt"><B>UNITED STATES<BR>
SECURITIES AND EXCHANGE COMMISSION<BR>
<FONT style="font-size: 12pt">Washington, D.C. 20549
</FONT></B>

<P align="center" style="font-size: 18pt"><B>FORM 8-K</B>

<P align="center" style="font-size: 12pt"><B>CURRENT REPORT<BR>
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934</B>

<P align="center" style="font-size: 10pt"><B>Date of Report (Date of earliest event reported): February 20, 2009</B>

<P align="center">

<P align="center" style="font-size: 24pt"><B>SPECTRUM PHARMACEUTICALS, INC.<BR></B>
<FONT style="font-size: 10pt">(Exact name of registrant as specified in its charter)
</FONT>

<TABLE border="0" width="100%" cellspacing="0" cellpadding="0" style="font-size: 10pt; text-align: center">
<TR>
    <TD width="32%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="33%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="32%">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD style="border-bottom: 1px solid #000000"><B>Delaware</B></TD>
    <TD>&nbsp;</TD>
    <TD style="border-bottom: 1px solid #000000"><B>000-28782</B></TD>
    <TD>&nbsp;</TD>
    <TD style="border-bottom: 1px solid #000000"><B>93-0979187</B></TD>
</TR>
<TR valign="top">
    <TD>(State or other Jurisdiction of Incorporation)</TD>
    <TD>&nbsp;</TD>
    <TD>(Commission File Number)</TD>
    <TD>&nbsp;</TD>
    <TD>(IRS Employer Identification No.)</TD>
</TR>
</TABLE>

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    <TD width="49%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="49%">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD style="border-bottom: 1px solid #000000"><B>157 Technology Drive, Irvine, California<BR></B></TD>
    <TD>&nbsp;</TD>
    <TD style="border-bottom: 1px solid #000000"><B>92618</B></TD>
</TR>
<TR valign="top">
    <TD>(Address of Principal Executive Offices)</TD>
    <TD>&nbsp;</TD>
    <TD>(Zip Code)</TD>
</TR>
</TABLE>

<P align="center" style="font-size: 10pt">Registrant&#146;s telephone number, including area code: <B>(949) 788-6700</B>


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    <TD nowrap style="border-bottom: 1px solid #000000"><B>Not Applicable<BR></B></TD>
</TR>
<TR>
    <TD nowrap>(Former name or former address if changed since last report.)</TD>
</TR>
</TABLE>

<P align="left" style="font-size: 10pt">Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant
under any of the following provisions:

<P align="left" style="font-size: 10pt">
<FONT face="Wingdings">&#111;</FONT> Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)<BR><BR>
<FONT face="Wingdings">&#111;</FONT> Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)<BR><BR>
<FONT face="Wingdings">&#111;</FONT> Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))<BR><BR>
<FONT face="Wingdings">&#111;</FONT> Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))<BR>


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<P align="center" style="font-size: 10pt; display: none">1
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    <TD width="7%"></TD>
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    <TD></TD>
</TR>
<TR valign="top">
    <TD nowrap align="left"><B>Item&nbsp;2.03</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Creation of a Direct Financial Obligation or an Obligation Under an Off-Balance Sheet Arrangement of a Registrant.</B></TD>
</TR>
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</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">On February&nbsp;20, 2009, Spectrum Pharmaceuticals, Inc. (&#147;<U>Spectrum</U>&#148;) received a written
notice from Cell Therapeutics, Inc. (&#147;<U>CTI</U>&#148;) stating that CTI had elected to exercise its
option to require Spectrum to purchase CTI&#146;s 50% membership interest in RIT Oncology, LLC
(&#147;<U>RIT</U>&#148;), a 50/50-owned joint venture (the &#147;<U>Joint Venture</U>&#148;) formed by Spectrum and
CTI in December&nbsp;2008 to commercialize and develop Zevalin<SUP style="font-size: 85%; vertical-align: text-top">&#174;</SUP> (ibritumomab tiuxetan) in the United
States. Spectrum owns the remaining 50% membership interest in the Joint Venture. Spectrum&#146;s
obligation to consummate the purchase of CTI&#146;s membership interest is subject to specified closing
conditions, including CTI obtaining all necessary material third party consents and approvals
and the delivery to Spectrum of a legal opinion of outside counsel to CTI.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">Pursuant to the terms of the Joint Venture&#146;s operating agreement, Spectrum is required to
purchase, subject to the specified closing conditions, all of CTI&#146;s membership interest in the
Joint Venture for $18.0&nbsp;million (subject to adjustment for any amounts owed between CTI and RIT at
the time of sale) within 30&nbsp;days of the delivery of CTI&#146;s notice of exercise of its sale option.
The operating agreement further permits Spectrum to either pay the entire purchase price in a lump
sum at the closing of the sale, or to pay the purchase price in
three installments (the first at the closing, and the second two 45
and 90&nbsp;days after the closing). The post-closing installment
payments would be subject to a full-recourse, non-interest-bearing
promissory note issued by Spectrum to CTI at the closing. Prior to the closing CTI is required to pay a transfer consent fee of
$750,000 to Biogen IDEC Inc. (&#147;Biogen&#148;) pursuant to certain agreements between Biogen and CTI that
were entered into in connection with the formation of the Joint Venture.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">Additional information regarding the Joint Venture can be found in Spectrum&#146;s Current Report
on Form 8-K filed with the Securities and Exchange Commission (the &#147;SEC&#148;) on December&nbsp;19, 2008. A
copy of the press release Spectrum issued on February&nbsp;23, 2009 to announce CTI&#146;s exercise of the
sale option and certain other matters is attached as Exhibit&nbsp;99.1 hereto.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">This Current Report on Form 8-K contains forward-looking statements within the meaning of
Section&nbsp;27A of the Securities Act of 1933, as amended, and Section&nbsp;21E of the Securities Exchange
Act of 1934, as amended. Such statements may contain words such as &#147;will,&#148; &#147;expect,&#148; &#147;believe,&#148; or
the negative thereof or comparable terminology, and may include (without limitation) information
regarding Spectrum&#146;s expectations, goals or intentions regarding the future, including but not
limited to statements regarding CTI&#146;s exercise of its sale option and the consummation of the
transactions contemplated thereby. Forward-looking statements involve certain risks and
uncertainties, and actual results may differ materially from those discussed in any such statement.
In particular, Spectrum can provide no assurances that the conditions to the closing of its
acquisition of CTI&#146;s interest in the Joint Venture will be satisfied. Additional factors that
could cause actual results to differ are described in further detail in Spectrum&#146;s reports filed
with the SEC, including without limitation its Annual Report on Form 10-K for the year ended
December&nbsp;31, 2007 and its subsequent Quarterly Reports on Form 10-Q.
All forward looking statements in this Current Report on Form 8-K speak only as of the date hereof.
Spectrum does not plan to update any such forward-looking statements and expressly disclaims any
duty to update the information contained herein except as required by law.
</DIV>
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<TR valign="top">
    <TD nowrap align="left"><B>Item&nbsp;9.01</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Financial Statements and Exhibits.</B></TD>
</TR>
</TABLE>
</DIV>

<DIV style="margin-top: 10pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(d)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Exhibits.</TD>
</TR>

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    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="right" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.1</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Press Release dated February&nbsp;23, 2009.</TD>
</TR>
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<P align="center" style="font-size: 10pt"><!-- Folio -->3<!-- /Folio -->
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<DIV align="center" style="font-size: 10pt; margin-top: 10pt"><B>SIGNATURES</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly
caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
</DIV>

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    <TD width="15%">&nbsp;</TD>
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<TR>
    <TD valign="top" align="left"><B>February 26, 2009</B>      &nbsp;</TD>
    <TD colspan="3" align="left">SPECTRUM PHARMACEUTICALS, INC.<BR>
&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">&nbsp;</TD>
    <TD valign="top">By:&nbsp;&nbsp;</TD>
    <TD colspan="2" style="border-bottom: 1px solid #000000" align="left">                              /s/ Shyam Kumaria
&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top">Name:&nbsp;&nbsp;</TD>
    <TD align="left">Shyam Kumaria&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top">Title:&nbsp;&nbsp;</TD>
    <TD align="left">V.P. Finance&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR>
    <TD colspan="5">&nbsp;</TD>
</TR>
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<DIV align="center" style="font-size: 10pt; margin-top: 10pt"><B>Exhibit&nbsp;List</B>
</DIV>

<DIV align="center">
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    <TD width="92%">&nbsp;</TD>
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<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">99.1
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Press Release dated February&nbsp;23, 2009.</TD>
</TR>
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Filed by Bowne Pure Compliance
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
Date of Report (Date of earliest event reported): February 20, 2009
SPECTRUM PHARMACEUTICALS, INC.
(Exact name of registrant as specified in its charter)
Delaware
000-28782
93-0979187
(State or other Jurisdiction of Incorporation)
(Commission File Number)
(IRS Employer Identification No.)
157 Technology Drive, Irvine, California
92618
(Address of Principal Executive Offices)
(Zip Code)
Registrant's telephone number, including area code:
(949) 788-6700
Not Applicable
(Former name or former address if changed since last report.)
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant
under any of the following provisions:
o
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
o
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
o
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
o
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Item 2.03
Creation of a Direct Financial Obligation or an Obligation Under an Off-Balance Sheet Arrangement of a Registrant.
On February 20, 2009, Spectrum Pharmaceuticals, Inc. ("
Spectrum
") received a written
notice from Cell Therapeutics, Inc. ("
CTI
") stating that CTI had elected to exercise its
option to require Spectrum to purchase CTI's 50% membership interest in RIT Oncology, LLC
("
RIT
"), a 50/50-owned joint venture (the "
Joint Venture
") formed by Spectrum and
CTI in December 2008 to commercialize and develop Zevalin
®
(ibritumomab tiuxetan) in the United
States. Spectrum owns the remaining 50% membership interest in the Joint Venture. Spectrum's
obligation to consummate the purchase of CTI's membership interest is subject to specified closing
conditions, including CTI obtaining all necessary material third party consents and approvals
and the delivery to Spectrum of a legal opinion of outside counsel to CTI.
Pursuant to the terms of the Joint Venture's operating agreement, Spectrum is required to
purchase, subject to the specified closing conditions, all of CTI's membership interest in the
Joint Venture for $18.0 million (subject to adjustment for any amounts owed between CTI and RIT at
the time of sale) within 30 days of the delivery of CTI's notice of exercise of its sale option.
The operating agreement further permits Spectrum to either pay the entire purchase price in a lump
sum at the closing of the sale, or to pay the purchase price in
three installments (the first at the closing, and the second two 45
and 90 days after the closing). The post-closing installment
payments would be subject to a full-recourse, non-interest-bearing
promissory note issued by Spectrum to CTI at the closing. Prior to the closing CTI is required to pay a transfer consent fee of
$750,000 to Biogen IDEC Inc. ("Biogen") pursuant to certain agreements between Biogen and CTI that
were entered into in connection with the formation of the Joint Venture.
Additional information regarding the Joint Venture can be found in Spectrum's Current Report
on Form 8-K filed with the Securities and Exchange Commission (the "SEC") on December 19, 2008. A
copy of the press release Spectrum issued on February 23, 2009 to announce CTI's exercise of the
sale option and certain other matters is attached as Exhibit 99.1 hereto.
This Current Report on Form 8-K contains forward-looking statements within the meaning of
Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange
Act of 1934, as amended. Such statements may contain words such as "will," "expect," "believe," or
the negative thereof or comparable terminology, and may include (without limitation) information
regarding Spectrum's expectations, goals or intentions regarding the future, including but not
limited to statements regarding CTI's exercise of its sale option and the consummation of the
transactions contemplated thereby. Forward-looking statements involve certain risks and
uncertainties, and actual results may differ materially from those discussed in any such statement.
In particular, Spectrum can provide no assurances that the conditions to the closing of its
acquisition of CTI's interest in the Joint Venture will be satisfied. Additional factors that
could cause actual results to differ are described in further detail in Spectrum's reports filed
with the SEC, including without limitation its Annual Report on Form 10-K for the year ended
December 31, 2007 and its subsequent Quarterly Reports on Form 10-Q.
All forward looking statements in this Current Report on Form 8-K speak only as of the date hereof.
Spectrum does not plan to update any such forward-looking statements and expressly disclaims any
duty to update the information contained herein except as required by law.
2
Item 9.01
Financial Statements and Exhibits.
(d)
Exhibits.
99.1
Press Release dated February 23, 2009.
3
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly
caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
February 26, 2009
SPECTRUM PHARMACEUTICALS, INC.
By:
/s/ Shyam Kumaria
Name:
Shyam Kumaria
Title:
V.P. Finance
4
Exhibit List
99.1
Press Release dated February 23, 2009.
5