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<TITLE>Filed by Bowne Pure Compliance</TITLE>
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<P align="center" style="font-size: 14pt"><B>UNITED STATES<BR>
SECURITIES AND EXCHANGE COMMISSION<BR>
<FONT style="font-size: 12pt">Washington, D.C. 20549
</FONT></B>

<P align="center" style="font-size: 18pt"><B>FORM 8-K</B>

<P align="center" style="font-size: 12pt"><B>CURRENT REPORT<BR>
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934</B>

<P align="center" style="font-size: 10pt"><B>Date of Report (Date of earliest event reported): FEBRUARY 2, 2009</B>

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<P align="center" style="font-size: 24pt"><B>ISOLAGEN, INC.<BR></B>
<FONT style="font-size: 10pt">(Exact name of registrant as specified in its charter)
</FONT>

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    <TD width="32%">&nbsp;</TD>
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    <TD style="border-bottom: 1px solid #000000"><B>DELAWARE</B></TD>
    <TD>&nbsp;</TD>
    <TD style="border-bottom: 1px solid #000000"><B>001-31564</B></TD>
    <TD>&nbsp;</TD>
    <TD style="border-bottom: 1px solid #000000"><B>87-0458888</B></TD>
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<TR valign="top">
    <TD>(State or other Jurisdiction of Incorporation)</TD>
    <TD>&nbsp;</TD>
    <TD>(Commission File Number)</TD>
    <TD>&nbsp;</TD>
    <TD>(IRS Employer Identification No.)</TD>
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    <TD width="49%">&nbsp;</TD>
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    <TD style="border-bottom: 1px solid #000000"><B>405 EAGLEVIEW BLVD., EXTON, PA<BR></B></TD>
    <TD>&nbsp;</TD>
    <TD style="border-bottom: 1px solid #000000"><B>19341</B></TD>
</TR>
<TR valign="top">
    <TD>(Address of Principal Executive Offices)</TD>
    <TD>&nbsp;</TD>
    <TD>(Zip Code)</TD>
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<P align="center" style="font-size: 10pt">Registrant&#146;s telephone number, including area code: <B>(484) 713-6000</B>


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    <TD nowrap style="border-bottom: 1px solid #000000"><B>NOT APPLICABLE<BR></B></TD>
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<TR>
    <TD nowrap>(Former name or former address if changed since last report.)</TD>
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<P align="left" style="font-size: 10pt">Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant
under any of the following provisions:

<P align="left" style="font-size: 10pt">
<FONT face="Wingdings">&#111;</FONT> Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)<BR><BR>
<FONT face="Wingdings">&#111;</FONT> Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)<BR><BR>
<FONT face="Wingdings">&#111;</FONT> Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))<BR><BR>
<FONT face="Wingdings">&#111;</FONT> Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))<BR>


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<DIV align="justify" style="font-size: 10pt; margin-top: 10pt"><B>Item&nbsp;8.01 Other Events</B>
</DIV>


<DIV align="justify" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">As previously reported on January&nbsp;15, 2009 on SEC Form 8-K, as of January&nbsp;15, 2009 the Company
had a debt liability of $90,000,000 related to its 3.5% Convertible Subordinated Notes (the &#147;3.5%
Subordinated Notes&#148;), which could be called due, at the option of the note holders, as early as
November&nbsp;2009.
</DIV>

<DIV align="justify" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">At the option of the note holders, the 3.5% Subordinated Notes may be converted into Isolagen
common stock at a rate of 109.2001 shares of Isolagen common stock for each $1,000 principal amount
of the Notes, which is equivalent to a conversion price of approximately $9.16 per common share.
</DIV>

<DIV align="justify" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">On February&nbsp;2, 2009, a note holder converted $344,000 of the 3.5% Subordinated Notes into
37,564 common shares of the Company.
</DIV>

<DIV align="justify" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">Accordingly, as of February&nbsp;2, 2009, the Company has a remaining debt liability of $89,656,000
related to its 3.5% Subordinated Notes, which could be called due, at the option of the note
holders, as early as November&nbsp;2009. Interest on the notes is due semiannually on May 1 and
November 1. Please refer to the Company&#146;s SEC Form 10-K for the year ended December&nbsp;31, 2007 for
further information with respect to the 3.5% Subordinated Notes. Please refer to the Company&#146;s
Current Report on Form 8-K filed January&nbsp;15, 2009 for additional information concerning the
Company&#146;s current financial condition and operating plan.
</DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 10pt"><U><B>SIGNATURE</B></U>
</DIV>


<DIV align="justify" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">Pursuant to the requirements of the Securities and Exchange Act of 1934, the registrant has
duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
</DIV>

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    <TD colspan="3" align="left"><B>ISOLAGEN, INC.</B><BR>
&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">Date: February 3, 2009&nbsp;</TD>
    <TD valign="top">By:&nbsp;&nbsp;</TD>
    <TD colspan="2" style="border-bottom: 1px solid #000000" align="left">/s/ Todd J. Greenspan
&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD colspan="2" align="left">Todd J. Greenspan,&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD colspan="2" align="left">Chief Financial Officer&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
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{"company-data": {"conformed-name": "ISOLAGEN INC", "cik": "0000357097", "assigned-sic": "2834", "irs-number": "870458888", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "001-31564", "film-number": "09566953"}, "business-address": {"street1": "2500 WILCREST", "street2": "5TH FLOOR", "city": "HOUSTON", "state": "TX", "zip": "77042", "phone": "713-780-4754"}, "mail-address": {"street1": "2500 WILCREST", "street2": "5TH FLOOR", "city": "HOUSTON", "state": "TX", "zip": "77042"}, "former-company": [{"former-conformed-name": "AMERICAN FINANCIAL HOLDING INC /DE", "date-changed": "19960330"}, {"former-conformed-name": "AMERICAN FINANCIAL HOLDING INC /CO", "date-changed": "19921008"}, {"former-conformed-name": "VIDTOR COMMUNICATIONS INC", "date-changed": "19920721"}]}
Filed by Bowne Pure Compliance
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
Date of Report (Date of earliest event reported): FEBRUARY 2, 2009
ISOLAGEN, INC.
(Exact name of registrant as specified in its charter)
DELAWARE
001-31564
87-0458888
(State or other Jurisdiction of Incorporation)
(Commission File Number)
(IRS Employer Identification No.)
405 EAGLEVIEW BLVD., EXTON, PA
19341
(Address of Principal Executive Offices)
(Zip Code)
Registrant's telephone number, including area code:
(484) 713-6000
NOT APPLICABLE
(Former name or former address if changed since last report.)
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant
under any of the following provisions:
o
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
o
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
o
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
o
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Item 8.01 Other Events
As previously reported on January 15, 2009 on SEC Form 8-K, as of January 15, 2009 the Company
had a debt liability of $90,000,000 related to its 3.5% Convertible Subordinated Notes (the "3.5%
Subordinated Notes"), which could be called due, at the option of the note holders, as early as
November 2009.
At the option of the note holders, the 3.5% Subordinated Notes may be converted into Isolagen
common stock at a rate of 109.2001 shares of Isolagen common stock for each $1,000 principal amount
of the Notes, which is equivalent to a conversion price of approximately $9.16 per common share.
On February 2, 2009, a note holder converted $344,000 of the 3.5% Subordinated Notes into
37,564 common shares of the Company.
Accordingly, as of February 2, 2009, the Company has a remaining debt liability of $89,656,000
related to its 3.5% Subordinated Notes, which could be called due, at the option of the note
holders, as early as November 2009. Interest on the notes is due semiannually on May 1 and
November 1. Please refer to the Company's SEC Form 10-K for the year ended December 31, 2007 for
further information with respect to the 3.5% Subordinated Notes. Please refer to the Company's
Current Report on Form 8-K filed January 15, 2009 for additional information concerning the
Company's current financial condition and operating plan.
SIGNATURE
Pursuant to the requirements of the Securities and Exchange Act of 1934, the registrant has
duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
ISOLAGEN, INC.
Date: February 3, 2009
By:
/s/ Todd J. Greenspan
Todd J. Greenspan,
Chief Financial Officer