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<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=4><B>UNITED STATES
<BR>
SECURITIES AND EXCHANGE COMMISSION</B></FONT>
<BR>
<FONT FACE="Times New Roman, Times, Serif" SIZE=2>Washington, D.C. 20549</FONT></P>

<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=4>FORM 8-K </FONT></H1>

<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE="3"><B>CURRENT REPORT
<BR></B> </FONT>
<FONT FACE="Times New Roman, Times, Serif" SIZE="2"><B>Pursuant to Section 13 or 15(d)
<BR>
of the Securities Exchange Act of 1934</B> </FONT>
<BR><BR>
<FONT FACE="Times New Roman, Times, Serif" SIZE="2">Date of Report (Date of earliest event reported): April 22, 2004 </FONT>
</P>

<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE="5"><B>MOLECULAR DEVICES CORPORATION</B> </FONT>
<BR>
<FONT FACE="Times New Roman, Times, Serif" SIZE="2">(Exact name of registrant as specified in its charter) </FONT>
<BR>
<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2><B>Delaware</B></FONT>
<BR>
(State or other jurisdiction of incorporation)</P>




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     <TD WIDTH="50%" ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><B>0-27316</B> </FONT></TD>
     <TD WIDTH="50%" ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><B>94-2914362</B> </FONT></TD></TR>
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     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">(Commission File Number) </FONT></TD>
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">(IRS Employer Identification No.) </FONT></TD></TR>
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<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2><B>1311 Orleans Drive
<BR>
Sunnyvale, CA 94089</B>
<BR>
(Address of Principal Executive Offices, including Zip Code)
<BR><BR>
Registrant&#146;s telephone number, including area code: (408) 747-1700
<BR>
_________________ </FONT></P>



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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2><B>Item&nbsp;12.&nbsp;&nbsp;&nbsp;&nbsp;
     Results of Operations and Financial Condition.</B> </FONT></P>

<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>On April 22, 2004,  Molecular Devices Corporation  (&#147;Molecular  Devices&#148;)
reported its revenue and earnings for the quarter ended March 31, 2004. A copy of the press release  issued by Molecular
Devices on April 22, 2004,  concerning  the foregoing  results is furnished
herewith as Exhibit 99.1 and is incorporated herein by reference.</FONT></P>

<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
The  information  in this report,  including  the exhibit  hereto,  shall not be deemed to be &#147;filed&#148; for purposes of Section 18 of the
Securities  Exchange Act of 1934, as amended,  or otherwise  subject to the  liabilities of that Section or Sections 11 and 12(a)(2) of
the Securities Act of 1933, as amended.  The information  contained herein and in the accompanying exhibit shall not be incorporated by
reference into any filing with the U.S.  Securities and Exchange  Commission  made by Molecular  Devices,  whether made before or after
the date hereof, regardless of any general incorporation language in such filing.</FONT></P>


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<A NAME=A018></A>
<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>SIGNATURE </FONT></H1>

<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant
to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused
this report to be signed on its behalf by the undersigned, thereunto duly authorized. </FONT></P>


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     <TD WIDTH=42% ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;</FONT></TD>
     <TD WIDTH=8% ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;</FONT></TD>
     <TD WIDTH=50% ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2><B>MOLECULAR DEVICES CORPORATION</B></FONT></TD></TR>
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     <TD ALIGN=RIGHT>&nbsp;</TD>
     <TD ALIGN=RIGHT>&nbsp;</TD>
     <TD ALIGN=RIGHT>&nbsp;</TD></TR>
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     <TD ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Dated: April 22, 2004</FONT></TD>
     <TD ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;</FONT></TD>
     <TD ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>By:&nbsp;&nbsp;&nbsp;&nbsp;/s/ Timothy A. Harkness</FONT></TD></TR>
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     <TD ALIGN=RIGHT><HR NOSHADE COLOR=Black SIZE=1></TD></TR>
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     <TD ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;</FONT></TD>
     <TD ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;</FONT></TD>
     <TD ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Timothy A. Harkness</FONT></TD></TR>
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     <TD ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;</FONT></TD>
     <TD ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;</FONT></TD>
     <TD ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Vice President and Chief</FONT></TD></TR>
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     <TD ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;</FONT></TD>
     <TD ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;</FONT></TD>
     <TD ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Financial Officer</FONT></TD></TR>
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<A NAME=A019></A>
<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>INDEX TO EXHIBITS </FONT></H1>

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<TD WIDTH="2%"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>99.1</FONT></TD>
<TD WIDTH="2%"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;</FONT></TD>
<TD WIDTH="96%"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Press release, dated as of April 22, 2004, reporting Molecular Devices  Corporation&#146;s revenue and earnings for the quarter ended March
31, 2004 (furnished and not filed herewith solely pursuant to Item 12). </FONT></TD>
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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d)
of the Securities Exchange Act of 1934
Date of Report (Date of earliest event reported): April 22, 2004
MOLECULAR DEVICES CORPORATION
(Exact name of registrant as specified in its charter)
Delaware
(State or other jurisdiction of incorporation)
0-27316
94-2914362
(Commission File Number)
(IRS Employer Identification No.)
1311 Orleans Drive
Sunnyvale, CA 94089
(Address of Principal Executive Offices, including Zip Code)
Registrant's telephone number, including area code: (408) 747-1700
_________________
Item 12.    
     Results of Operations and Financial Condition.
On April 22, 2004,  Molecular Devices Corporation  ("Molecular  Devices")
reported its revenue and earnings for the quarter ended March 31, 2004. A copy of the press release  issued by Molecular
Devices on April 22, 2004,  concerning  the foregoing  results is furnished
herewith as Exhibit 99.1 and is incorporated herein by reference.
The  information  in this report,  including  the exhibit  hereto,  shall not be deemed to be "filed" for purposes of Section 18 of the
Securities  Exchange Act of 1934, as amended,  or otherwise  subject to the  liabilities of that Section or Sections 11 and 12(a)(2) of
the Securities Act of 1933, as amended.  The information  contained herein and in the accompanying exhibit shall not be incorporated by
reference into any filing with the U.S.  Securities and Exchange  Commission  made by Molecular  Devices,  whether made before or after
the date hereof, regardless of any general incorporation language in such filing.
SIGNATURE
Pursuant
to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused
this report to be signed on its behalf by the undersigned, thereunto duly authorized.
MOLECULAR DEVICES CORPORATION
Dated: April 22, 2004
By:    /s/ Timothy A. Harkness
Timothy A. Harkness
Vice President and Chief
Financial Officer
INDEX TO EXHIBITS
99.1
Press release, dated as of April 22, 2004, reporting Molecular Devices  Corporation's revenue and earnings for the quarter ended March
31, 2004 (furnished and not filed herewith solely pursuant to Item 12).