content: SECURITIES AND EXCHANGE COMMISSION
                                WASHINGTON, DC 20549
  
                                  ----------------
  
                                      FORM 8-K
  
                                   CURRENT REPORT
                         PURSUANT TO SECTION 13 OR 15(D) OF
                         THE SECURITIES EXCHANGE ACT OF 1934
  
  
         Date of report (Date of earliest event reported) September 15, 1998
  
  
                                     SCIOS INC.
                 (Exact Name of Registrant as Specified in Charter)
  
  
  
      Delaware                       0-11749                       95-3701481
  (State of Other Jurisdiction      (Commission                   (IRS Employer
    of Incorporation)                File Number)              Identification No.)
  
  
  
               2450 Bayshore Parkway, Mountain View, California 94043
                      (Address of Principal Executive Offices)
  
  
  
          Registrant's telephone number, including area code (650) 966-1550
  
  
  
  
  
  
  <PAGE>
  
  
  
  
  Item 5.  Other Events
  
           On  September  15, 1998,  Scios Inc.  announced  that it had  appointed
  Richard B. Brewer as President  and Chief  Executive  Officer and a director and
  that Richard L. Casey had retired as an officer and director.  The press release
  is attached hereto as Exhibit 99.1 and incorporated herein by reference.
  
  
  Exhibits.
  
           99.1     Press Release dated September 15, 1998
  
  
  
  
  
  
  
  
  
           Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
  the  registrant has duly caused this amendment to be signed on its behalf of the
  undersigned, thereunto duly authorized.
  
                                              SCIOS INC.
  
  
  Date:  October 27, 1998                     By:     /s/ John H. Newman         
                                                    ------------------------------
                                                    John H. Newman
                                                    Senior Vice President
  
  
  <PAGE>
  
  
  
                                  INDEX TO EXHIBITS
  
                                     SCIOS INC.
  
                      Report on Form 8-K dated October 27, 1998
  
  
  <TABLE>
  <CAPTION>
  Exhibit           Description                                      Method of Filing
  <S>               <C>                                              <C>    
  99.1              Press Release dated September 15, 1998           Filed electronically herewith
  </TABLE>
metadata_documents: [{"type": "8-K", "sequence": "1", "description": "FORM 8-K", "secsgml_size_bytes": 2435}]
metadata_filer: {"company-data": {"conformed-name": "SCIOS INC", "cik": "0000726512", "assigned-sic": "2834", "irs-number": "953701481", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "000-11749", "film-number": "98732845"}, "business-address": {"street1": "2450 BAYSHORE PKWY", "city": "MOUNTAIN VIEW", "state": "CA", "zip": "94043", "phone": "4159661550"}, "mail-address": {"street1": "2450 BAYSHORE PARKWAY", "city": "MOUNTAIN VIEW", "state": "CA", "zip": "94043"}, "former-company": [{"former-conformed-name": "SCIOS INC", "date-changed": "19920703"}, {"former-conformed-name": "CALIFORNIA BIOTECHNOLOGY INC", "date-changed": "19920302"}]}
text: SECURITIES AND EXCHANGE COMMISSION
                                WASHINGTON, DC 20549
  
                                  ----------------
  
                                      FORM 8-K
  
                                   CURRENT REPORT
                         PURSUANT TO SECTION 13 OR 15(D) OF
                         THE SECURITIES EXCHANGE ACT OF 1934
  
         Date of report (Date of earliest event reported) September 15, 1998
  
                                     SCIOS INC.
                 (Exact Name of Registrant as Specified in Charter)
  
      Delaware                       0-11749                       95-3701481
  (State of Other Jurisdiction      (Commission                   (IRS Employer
    of Incorporation)                File Number)              Identification No.)
  
               2450 Bayshore Parkway, Mountain View, California 94043
                      (Address of Principal Executive Offices)
  
          Registrant's telephone number, including area code (650) 966-1550
  Item 5.  Other Events
  
           On  September  15, 1998,  Scios Inc.  announced  that it had  appointed
  Richard B. Brewer as President  and Chief  Executive  Officer and a director and
  that Richard L. Casey had retired as an officer and director.  The press release
  is attached hereto as Exhibit 99.1 and incorporated herein by reference.
  
  Exhibits.
  
           99.1     Press Release dated September 15, 1998
  
           Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
  the  registrant has duly caused this amendment to be signed on its behalf of the
  undersigned, thereunto duly authorized.
  
                                              SCIOS INC.
  
  Date:  October 27, 1998                     By:     /s/ John H. Newman         
                                                    ------------------------------
                                                    John H. Newman
                                                    Senior Vice President
  INDEX TO EXHIBITS
  
                                     SCIOS INC.
  
                      Report on Form 8-K dated October 27, 1998
  Exhibit           Description                                      Method of Filing
  99.1              Press Release dated September 15, 1998           Filed electronically herewith