content: <PAGE>
                                                   Conformed Copy
  
  
  
  
                                  
                 SECURITIES AND EXCHANGE COMMISSION
                       Washington, D.C. 20549
                                  
                                  
                              FORM 8-K
                                  
                           CURRENT REPORT
                                  
                  Pursuant to Section 13 or 15(d)
               of the Securities Exchange Act of 1934
                                  
                                  
   Date of Report (Date of earliest event reported): January 22, 1998
                                                     ----------------      
                                 
                         CYTOGEN CORPORATION               
       ------------------------------------------------------
       (Exact name of registrant as specified in its charter)
                                  
                                  
         Delaware             333-02015              22-2322400 
     ---------------         -----------        -------------------    
     (State or other         (Commission           (IRS Employer
     jurisdiction of           File No.)        Identification No.)
     Incorporation or 
     Organization)                             
                                  
   600 College Road East, CN 5308, Princeton, New Jersey 08540-5308 
  -----------------------------------------------------------------
      (Address of principal executive offices)           (Zip Code) 
    
                                  
                                  
  Registrant's telephone number, including area code: (609)987-8200
                                                      -------------
                                                              
  
  <PAGE>
  
  Item 5.  Other Events.
           -------------  
  
       On January 22, 1998, CYTOGEN Corporation issued the attached
  press release.
  
  
  Item 7.  Exhibits.
           ---------  
  
  99.1 Press release issued by CYTOGEN Corporation on January 22, 1998
  
  
                                    2    
  
  <PAGE>
                                                          
                               SIGNATURES
                                  
       Pursuant to the requirements of the Securities Exchange Act
  of 1934, the Registrant has duly caused this report to be signed
  on its behalf by the undersigned, thereunto duly authorized.
  
                                     CYTOGEN CORPORATION
  
  
  
                                     By  /s/ Donald F. Crane, Jr.   
                                         ------------------------          
                                         Name:  Donald F. Crane, Jr.
                                         Title: Vice President
                                                 General Counsel and Secretary
  
  
       
  Date: January 23, 1998
  
                                    3
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metadata_filer: {"company-data": {"conformed-name": "CYTOGEN CORP", "cik": "0000725058", "assigned-sic": "2835", "irs-number": "222322400", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "333-02015", "film-number": "98512252"}, "business-address": {"street1": "600 COLLEGE RD EAST CN 5308", "city": "PRINCETON", "state": "NJ", "zip": "08540", "phone": "6099878200"}, "mail-address": {"street1": "600 COLLEGE RD EAST CN 5308", "street2": "600 COLLEGE RD EAST CN 5308", "city": "PRINCETON", "state": "NJ", "zip": "08540"}}
text: Conformed Copy
  
                                  
                 SECURITIES AND EXCHANGE COMMISSION
                       Washington, D.C. 20549
                                  
                                  
                              FORM 8-K
                                  
                           CURRENT REPORT
                                  
                  Pursuant to Section 13 or 15(d)
               of the Securities Exchange Act of 1934
                                  
                                  
   Date of Report (Date of earliest event reported): January 22, 1998
                                                     ----------------      
                                 
                         CYTOGEN CORPORATION               
       ------------------------------------------------------
       (Exact name of registrant as specified in its charter)
                                  
                                  
         Delaware             333-02015              22-2322400 
     ---------------         -----------        -------------------    
     (State or other         (Commission           (IRS Employer
     jurisdiction of           File No.)        Identification No.)
     Incorporation or 
     Organization)                             
                                  
   600 College Road East, CN 5308, Princeton, New Jersey 08540-5308 
  -----------------------------------------------------------------
      (Address of principal executive offices)           (Zip Code) 
    
                                  
                                  
  Registrant's telephone number, including area code: (609)987-8200
                                                      -------------
  Item 5.  Other Events.
           -------------  
  
       On January 22, 1998, CYTOGEN Corporation issued the attached
  press release.
  
  Item 7.  Exhibits.
           ---------  
  
  99.1 Press release issued by CYTOGEN Corporation on January 22, 1998
  
                                    2
  SIGNATURES
                                  
       Pursuant to the requirements of the Securities Exchange Act
  of 1934, the Registrant has duly caused this report to be signed
  on its behalf by the undersigned, thereunto duly authorized.
  
                                     CYTOGEN CORPORATION
  
                                     By  /s/ Donald F. Crane, Jr.   
                                         ------------------------          
                                         Name:  Donald F. Crane, Jr.
                                         Title: Vice President
                                                 General Counsel and Secretary
  
       
  Date: January 23, 1998
  
                                    3