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      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: -9pt" align="center"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 18pt; FONT-FAMILY: Times New Roman">UNITED
  STATES</font></div>
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  AND EXCHANGE COMMISSION</font></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: -9pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 12pt; FONT-FAMILY: Times New Roman">Washington,
  D.C. 20549</font></div>
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      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: -9pt" align="center"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 18pt; FONT-FAMILY: Times New Roman">FORM
  8-K</font></div>
      <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: -9pt" align="center"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">CURRENT
  REPORT</font></div>
      <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: -9pt" align="center"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">PURSUANT
  TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934</font></div>
      <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: -9pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Date of
  Report: November 2, 2009 (Date of earliest event reported)</font></div>
      <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: -9pt" align="center"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 18pt; FONT-FAMILY: Times New Roman"><font style="DISPLAY: inline; TEXT-DECORATION: underline">MICROFLUIDICS INTERNATIONAL
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  Identification No.)</font></div>
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  Ossipee Road</font></div>
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  of principal executive offices)</font></div>
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  (617) 969-5452</font></div>
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  filing is intended to simultaneously satisfy the filing obligation of the
  registrant under any of the following provisions (see General Instruction A.2.
  below):</a></font></div>
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        to Rule 425 under the&#160;&#160;Securities&#160;&#160;Act (17 CFR
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          <div style="WIDTH: 100%; TEXT-ALIGN: center"><font style="DISPLAY: inline; FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman">&#160;
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            <hr style="COLOR: black" noshade size="2">
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  </font></div>
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      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: -9pt" align="left"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Item
  2.02&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;Results
  of Operations and Financial Condition.</font></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: -9pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">On
  November 2, 2009, Microfluidics International Corporation issued a press release
  entitled &#8220;Microfluidics International Corporation Announces&#160;Third Quarter
  2009 Financial Results.&#8221;&#160;&#160;A copy of the press release is attached as
  Exhibit 99.1 to this report and is incorporated by reference into this Item
  2.02.</font></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">NON-GAAP
  FINANCIAL MEASURES: The attached press release addresses our financial results
  for the&#160;third quarter ended&#160;September 30, 2009, and contains
  disclosure of our non-GAAP EBITDA (Earnings Before Interest, Taxes, Depreciation
  and Amortization),&#160;non-GAAP Adjusted EBITDA,&#160;and non-GAAP basic and
  diluted EBITDA per share, which are not measures of financial performance
  calculated in accordance with generally accepted accounting principles (GAAP) in
  the United States. The press release contains disclosure regarding why we
  believe the presentation of these non-GAAP measures provides useful information
  to investors in analyzing our underlying business and operating performance. It
  also contains a tabular reconciliation of GAAP to non-GAAP financial information
  that is discussed in the release.</font></div>
      <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: -9pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">The
  information being provided in this report, including Exhibit 99.1, shall not be
  deemed to be &#8220;filed&#8221; for purposes of Section 18 of the Securities Exchange Act
  of 1934 (the &#8220;Exchange Act&#8221;) or otherwise subject to the liabilities of that
  section, nor shall it be deemed incorporated by reference in any filing under
  the Securities Act of 1933, as amended, or the Exchange Act, except as expressly
  set forth by specific reference in such a filing.</font></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
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  9.01&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;Financial
  Statements and Exhibits.</font></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: -9pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><font id="TAB1" style="MARGIN-LEFT: 36pt"></font>(d)&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;The
  following exhibit is hereby filed as part of this Current Report on Form
  8-K:</font></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: -9pt" align="left"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><font style="DISPLAY: inline; TEXT-DECORATION: underline">Number</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="DISPLAY: inline; TEXT-DECORATION: underline">Exhibit</font></font></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
      <div>
        <table align="center" border="0" cellpadding="0" cellspacing="0" id="hangingindent" width="100%" style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">
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              <td style="WIDTH: 98px">
                <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">99.1</font></div>
              </td>
              <td width="1139">
                <div align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Press
        Release titled &#8220;Microfluidics International Corporation
        Announces&#160;Third Quarter 2009 Financial
    Results&#8221;</font></div>
              </td>
            </tr></table>
      </div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify">&#160;</div><br>
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  </font></div>
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  </font></div>
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      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: -9pt" align="center"><a name="fis_regulation_fd"><br></a></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: -9pt" align="center"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">SIGNATURE</font></div>
      <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 36pt; MARGIN-RIGHT: -9pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Pursuant
  to the requirements of the Securities Exchange Act of 1934, the registrant has
  duly caused this report to be signed on its behalf by the undersigned hereunto
  duly authorized.</font></div>
      <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: -9pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Dated:
  November 2,
  2009&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="DISPLAY: inline; FONT-WEIGHT: bold">MICROFLUIDICS
  INTERNATIONAL</font><font id="TAB2" style="COLOR: black; LETTER-SPACING: 3pt">&#160;</font><font style="DISPLAY: inline; FONT-WEIGHT: bold">CORPORATION</font></font></div>
      <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: -9pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><font id="TAB1" style="MARGIN-LEFT: 252pt"></font>By: /s/ Peter F. Byczko</font></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: -9pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><font id="TAB1" style="MARGIN-LEFT: 252pt"></font>-----------------------------------</font></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: -9pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><font id="TAB1" style="MARGIN-LEFT: 252pt"></font>Name:&#160;&#160;Peter F.
  Byczko</font></div>
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                <div align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Title:&#160;&#160;&#160;Vice
        President of Finance &amp; Chief Accounting
    Officer</font></div>
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        Number</font></div>
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        Release titled &#8220;Microfluidics International Corporation
        Announces&#160;Third Quarter 2009 Financial
    Results&#8221;</font></div>
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text: q38k.htm
  UNITED
  STATES
  SECURITIES
  AND EXCHANGE COMMISSION
  Washington,
  D.C. 20549
  FORM
  8-K
  CURRENT
  REPORT
  PURSUANT
  TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
  Date of
  Report: November 2, 2009 (Date of earliest event reported)
  MICROFLUIDICS INTERNATIONAL
  CORPORATION
  (Exact
  name of registrant as specified in its charter)
  Delaware                                           
          0-11625                                           
  04-2793022
  (State or other
  jurisdiction of
  incorporation)           (Commission File
  Number)          (IRS Employer
  Identification No.)
  30
  Ossipee Road
  Newton,
  MA  02464
  (Address
  of principal executive offices)
  Telephone:
  (617) 969-5452
  (Registrant's
  telephone number, including area code)
  Check the appropriate box below if the Form 8-K
  filing is intended to simultaneously satisfy the filing obligation of the
  registrant under any of the following provisions (see General Instruction A.2.
  below):
  q
  Written  communications  pursuant
        to Rule 425 under the  Securities  Act (17 CFR
        230.425)
  q
  Soliciting  material  pursuant
        to Rule  14a-12  under
        the  Exchange  Act (17 CFR
    240.14a-12)
  q
  Pre-commencement
        communications pursuant to Rule 14d-2(b) under the Exchange Act (17CFR
        240.14d-2(b))
  q
  Pre-commencement
        communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR
        240.13e-4(c))
  Item
  2.02                      Results
  of Operations and Financial Condition.
  On
  November 2, 2009, Microfluidics International Corporation issued a press release
  entitled "Microfluidics International Corporation Announces Third Quarter
  2009 Financial Results."  A copy of the press release is attached as
  Exhibit 99.1 to this report and is incorporated by reference into this Item
  2.02.
  NON-GAAP
  FINANCIAL MEASURES: The attached press release addresses our financial results
  for the third quarter ended September 30, 2009, and contains
  disclosure of our non-GAAP EBITDA (Earnings Before Interest, Taxes, Depreciation
  and Amortization), non-GAAP Adjusted EBITDA, and non-GAAP basic and
  diluted EBITDA per share, which are not measures of financial performance
  calculated in accordance with generally accepted accounting principles (GAAP) in
  the United States. The press release contains disclosure regarding why we
  believe the presentation of these non-GAAP measures provides useful information
  to investors in analyzing our underlying business and operating performance. It
  also contains a tabular reconciliation of GAAP to non-GAAP financial information
  that is discussed in the release.
  The
  information being provided in this report, including Exhibit 99.1, shall not be
  deemed to be "filed" for purposes of Section 18 of the Securities Exchange Act
  of 1934 (the "Exchange Act") or otherwise subject to the liabilities of that
  section, nor shall it be deemed incorporated by reference in any filing under
  the Securities Act of 1933, as amended, or the Exchange Act, except as expressly
  set forth by specific reference in such a filing.
  Item
  9.01                      Financial
  Statements and Exhibits.
  (d)           The
  following exhibit is hereby filed as part of this Current Report on Form
  8-K:
  Number
  Exhibit
  99.1
  Press
        Release titled "Microfluidics International Corporation
        Announces Third Quarter 2009 Financial
    Results"
  SIGNATURE
  Pursuant
  to the requirements of the Securities Exchange Act of 1934, the registrant has
  duly caused this report to be signed on its behalf by the undersigned hereunto
  duly authorized.
  Dated:
  November 2,
  2009
  MICROFLUIDICS
  INTERNATIONAL
  CORPORATION
  By: /s/ Peter F. Byczko
  -----------------------------------
  Name:  Peter F.
  Byczko
  Title:   Vice
        President of Finance & Chief Accounting
    Officer
  EXHIBIT
  INDEX
  Exhibit
        Number
  Description
  99.1
  Press
        Release titled "Microfluidics International Corporation
        Announces Third Quarter 2009 Financial
    Results"