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  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
  
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              <p  align=center style='text-align:center'><b><font SIZE=2>UNITED STATES</font></b><b></b></p> </td> </tr>
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              <p  align=center style='text-align:center'><b><font SIZE=2>SECURITIES AND EXCHANGE COMMISSION</font></b><b></b></p> </td> </tr>
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              <p  align=center style='text-align:center'><b><font SIZE=2>WASHINGTON, D.C. 20549</font></b><b></b></p> </td> </tr>
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              <p  align=center style='text-align:center'><b><font size=2>________________________________________</font></b></p>
  <p  align=center style='text-align:center'><b><font SIZE=2>FORM 8-K</font></b><b></b></p> </td> </tr>
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              <p  align=center style='text-align:center'><b><font SIZE=2>CURRENT REPORT</font></b><b></b></p> </td> </tr>
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              <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center'><b><font size=2>PURSUANT TO SECTION 13 OR 15(d) OF THE</font></b><br> <b><font SIZE=2>SECURITIES EXCHANGE ACT OF 1934</font></b><b></b></p> </td> </tr>
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              <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center'><font size=1>&nbsp;</font></p> </td> </tr>
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              <p  align=center style='text-align:center'><font size=2>Date of report (Date of earliest event reported):&nbsp;&nbsp;</font><u><font size=2>May 5, 2005</font></u><u></u></p> </td> </tr>
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              <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=1>&nbsp;</font></td>
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              <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center'><font size=1>&nbsp;</font></p> </td> </tr>
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              <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=1>&nbsp;</font></td>
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              <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:0pt;margin-bottom:0pt'><font SIZE=2>CYTOGEN CORPORATION</font></p> </td>
          <td  width="146">
              <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=1>&nbsp;</font></td> </tr>
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              <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center'><b><font size=2>________________________________________</font></b><br> <font size=2>(Exact Name of Registrant as Specified in Charter)</font><b></b></p> </td> </tr>
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              <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center'><font size=1>&nbsp;</font></p> </td> </tr>
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              <div style='border-bottom:solid black 1.0pt; padding:0in 0in 1.0pt 0in'>
  <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center; padding:0in'><font size=2>Delaware</font></p> </div> </td>
          <td  colspan="2" valign=top style=' padding:0in 5.4pt 0in 5.4pt'>
              <div style='border-bottom:solid black 1.0pt; padding:0in 0in 1.0pt 0in'>
  <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center; padding:0in'><font size=2>000-14879</font></p> </div> </td>
          <td  colspan="2" valign=top style=' padding:0in 5.4pt 0in 5.4pt'>
              <div style='border-bottom:solid black 1.0pt; padding:0in 0in 1.0pt 0in'>
  <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center; padding:0in'><font size=2>22-2322400</font></p> </div> </td> </tr>
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              <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center'><font size=2>(State or Other Jurisdiction</font><br> <font size=2>of Incorporation)</font></p> </td>
          <td  colspan="2" valign=top style=' padding:0in 5.4pt 0in 5.4pt'>
              <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center'><font size=2>(Commission File Number)</font></p> </td>
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              <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center'><font size=2>(I.R.S. Employer</font><br> <font size=2>Identification No.)</font></p> </td> </tr>
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              <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center'><font size=1>&nbsp;</font></p> </td>
          <td  colspan="2" valign=top style=' padding:0in 5.4pt 0in 5.4pt'>
              <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center'><font size=1>&nbsp;</font></p> </td> </tr>
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              <div style='border-bottom:solid black 1.0pt; padding:0in 0in 1.0pt 0in'>
  <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center; padding:0in'><font size=2>650 College Road East, CN 5308, Suite 3100, Princeton, NJ</font></p> </div> </td>
          <td  colspan="2" valign=top style=' padding:0in 5.4pt 0in 5.4pt'>
              <div style='border-bottom:solid black 1.0pt; padding:0in 0in 1.0pt 0in'>
  <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center; padding:0in'><font size=2>08540</font></p> </div> </td> </tr>
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              <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center'><font size=2>(Address of Principal Executive Offices)</font></p> </td>
          <td  colspan="2" valign=top style=' padding:0in 5.4pt 0in 5.4pt'>
              <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center'><font size=2>(Zip Code)</font></p> </td> </tr>
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              <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center'><font size=1>&nbsp;</font></p> </td> </tr>
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              <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center'><font size=2>Registrant&#146;s telephone number, including area code:&nbsp;&nbsp;</font><u><font size=2>(609) 750-8200</font></u><u></u></p> </td> </tr>
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              <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center'><font size=1>&nbsp;</font></p> </td> </tr>
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              <p  align=center style='margin-bottom:0in;margin-bottom: .0001pt;text-align:center'><font size=1>&nbsp;</font></p> </td> </tr>
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  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:center;'><font size=2>(Former Name or Former Address, if Changed Since Last Report)</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:center;'><font size=2>&nbsp;</font></p>
  
  <p style=' margin-bottom:6pt; margin-top:0pt; text-indent:0.54in;text-align:justify;'><font size=2>Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (</font><i><font size=2>see </font></i><font size=2>General Instruction A.2. below):</font></p>
  
  <p style=' margin-bottom:6pt; margin-top:0pt; text-indent:0.54in;text-align:justify;'><font face=Wingdings>o</font><font size=2>  Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)&nbsp;&nbsp;</font></p>
  
  <p style=' margin-bottom:6pt; margin-top:0pt; text-indent:0.54in;text-align:justify;'><font face=Wingdings>o</font><font size=2>  Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)</font></p>
  
  <p style=' margin-bottom:6pt; margin-top:0pt; text-indent:0.54in;text-align:justify;'><font face=Wingdings>o</font><font size=2>  Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt; text-indent:0.54in;text-align:left;'><font face=Wingdings>o</font><font size=2>  Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))&nbsp;&nbsp;&nbsp;&nbsp;</font>
  </p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=1>&nbsp;</font></p>
  <br>
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  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
  
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              <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><b><font size=2>Item 5.03</font></b></p> </td>
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              <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><b><font size=2>Amendments to Articles of Incorporation or By-Laws; Change in Fiscal</font></b></p> </td> </tr>
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          <td  width="96">
              <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=1>&nbsp;</font></td>
          <td width="57" valign=top style='padding:0in 0in 6.0pt 0in'>
              <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><b><font size=2>Year.</font></b></p> </td>
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              <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=1>&nbsp;</font></td> </tr></table>
  
  <p style=' margin-bottom:0pt; margin-top:0pt; text-indent:0.67in;text-align:justify;'><font size=2>On May 5, 2005, the Board of Directors (the &#147;Board&#148;) of Cytogen Corporation (the &#147;Company&#148;) resolved to immediately amend Article III, Section 2 of the Company&#146;s By-Laws to increase the maximum number of directors permitted to serve on the Board to up to nine. The Company&#146;s Amended and Restated By-Laws are attached hereto as Exhibit 3.1 and incorporated herein by reference. The foregoing description of the Amended and Restated By-Laws is qualified in its entirety by reference to such Exhibit.</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
  
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              <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><b><font size=2>Item 9.01</font></b></p> </td>
          <td width="253" valign=top >
              <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><b><font size=2>Financial Statements and Exhibits</font></b></p> </td> </tr></table>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:justify;'><font size=2>&nbsp;</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>(c)  Exhibits.</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
  
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              <p  align=center style='text-align:center; text-indent:0in'><u><font size=2>Exhibit No.</font></u><u></u></p> </td>
          <td width="432" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
              <p  style='text-indent:0in'><u><font size=2>Description</font></u><u></u></p> </td> </tr>
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              <p  align=center style='text-align:center; text-indent:0in'><font size=2>3.1</font></p> </td>
          <td width="432" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
              <p  style='text-indent:0in'><font size=2>Amended and Restated By-Laws of Cytogen Corporation</font><b></b></p> </td> </tr></table>
  
  <p style=' margin-bottom:0pt; margin-top:0pt; text-indent:0.5in;text-align:justify;'><font size=2>&nbsp;</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'>
  </p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=1>&nbsp;</font></p>
  <br>
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  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
  <p style=' margin-bottom:30pt; margin-top:0pt;text-align:center;'><b><font SIZE=2>SIGNATURES</font></b></p>
  
  <p style=' margin-bottom:12pt; margin-top:0pt; text-indent:0.5in;text-align:justify;'><font size=2>Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:3.5in;text-align:left;'><font SIZE=2>CYTOGEN CORPORATION</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:3.5in;text-align:left;'><font size=2>&nbsp;</font></p>
  
  
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              <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=2>By:</font></p> </td>
          <td width="160" valign=top >
              <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><u><font size=2>/s/ Michael D. Becker</font></u></p> </td> </tr></table>
  
  <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:3.75in;text-align:left;'><font size=2>Michael D. Becker</font></p>
  
  <p style=' margin-bottom:12pt; margin-top:0pt; margin-left:3.75in;text-align:left;'><font size=2>President and Chief Executive Officer </font></p>
  
  
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              <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=2>Dated:</font></p> </td>
          <td width="108" valign=top style='padding:0in 0in 12.0pt 0in'>
              <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=2>May 11, 2005</font></p> </td> </tr></table>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'>
  </p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=1>&nbsp;</font></p>
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  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
  <p style=' margin-bottom:24pt; margin-top:0pt;text-align:center;'><b><font SIZE=2>EXHIBIT INDEX</font></b></p>
  
  
  <table border="0" cellspacing=0 cellpadding=0 width="535" style='margin-left:77.4pt;border-collapse:collapse'>
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              <p  align=center style='text-align:center; text-indent:0in'><u><font size=2>Exhibit No.</font></u><u></u></p> </td>
          <td width="427" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
              <p  style='text-indent:0in'><u><font size=2>Description</font></u><u></u></p> </td> </tr>
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          <td width="108" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
              <p  align=center style='text-align:center; text-indent:0in'><font size=2>3.1</font></p> </td>
          <td width="427" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
              <p  style='text-indent:0in'><font size=2>Amended and Restated By-Laws of Cytogen Corporation</font><b></b></p> </td> </tr></table>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:center;'><font size=2>&nbsp;</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:center;'><font size=2>&nbsp;</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
  <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=1>&nbsp;</font></p>
  
  
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metadata_documents: [{"type": "8-K", "sequence": "1", "filename": "form8-k_bylaws.htm", "description": "FORM 8-K AMENDED BY-LAWS", "secsgml_size_bytes": 19511}]
metadata_filer: {"company-data": {"conformed-name": "CYTOGEN CORP", "cik": "0000725058", "assigned-sic": "2834", "irs-number": "222322400", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "000-14879", "film-number": "05819887"}, "business-address": {"street1": "650 COLLEGE RD EAST STE 3100", "city": "PRINCETON", "state": "NJ", "zip": "08540", "phone": "6099878200"}, "mail-address": {"street1": "650 COLLEGE RD EAST STE 3100", "city": "PRINCETON", "state": "NJ", "zip": "08540"}}
text: UNITED STATES
  SECURITIES AND EXCHANGE COMMISSION
  WASHINGTON, D.C. 20549
  ________________________________________
  FORM 8-K
  CURRENT REPORT
  PURSUANT TO SECTION 13 OR 15(d) OF THE
  SECURITIES EXCHANGE ACT OF 1934
  Date of report (Date of earliest event reported):
  May 5, 2005
  CYTOGEN CORPORATION
  ________________________________________
  (Exact Name of Registrant as Specified in Charter)
  Delaware
  000-14879
  22-2322400
  (State or Other Jurisdiction
  of Incorporation)
  (Commission File Number)
  (I.R.S. Employer
  Identification No.)
  650 College Road East, CN 5308, Suite 3100, Princeton, NJ
  08540
  (Address of Principal Executive Offices)
  (Zip Code)
  Registrant's telephone number, including area code:
  (609) 750-8200
  (Former Name or Former Address, if Changed Since Last Report)
  Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (
  see
  General Instruction A.2. below):
  o
  Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
  o
  Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
  o
  Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
  o
  Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
  Item 5.03
  Amendments to Articles of Incorporation or By-Laws; Change in Fiscal
  Year.
  On May 5, 2005, the Board of Directors (the "Board") of Cytogen Corporation (the "Company") resolved to immediately amend Article III, Section 2 of the Company's By-Laws to increase the maximum number of directors permitted to serve on the Board to up to nine. The Company's Amended and Restated By-Laws are attached hereto as Exhibit 3.1 and incorporated herein by reference. The foregoing description of the Amended and Restated By-Laws is qualified in its entirety by reference to such Exhibit.
  Item 9.01
  Financial Statements and Exhibits
  (c)  Exhibits.
  Exhibit No.
  Description
  3.1
  Amended and Restated By-Laws of Cytogen Corporation
  SIGNATURES
  Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
  CYTOGEN CORPORATION
  By:
  /s/ Michael D. Becker
  Michael D. Becker
  President and Chief Executive Officer
  Dated:
  May 11, 2005
  EXHIBIT INDEX
  Exhibit No.
  Description
  3.1
  Amended and Restated By-Laws of Cytogen Corporation