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Prepared and filed by St Ives Financial
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<p align="center"><font size="2" face="serif"><b>UNITED STATES<br>SECURITIES AND EXCHANGE COMMISSION<br>WASHINGTON, DC 20549</b></font></p>
<p align="center"><font size="2" face="serif"><b>FORM 8-K</b></font></p>
<p align="center"><font size="2" face="serif"><b>CURRENT REPORT<br>Pursuant to Section 13 or 15 (d) of the<br>Securities Exchange Act of 1934</b></font></p>
<p align="left"><font size="2" face="serif">Date of Report (Date of earliest event reported): <u><b>October 16, 2006</b></u></font></p>
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  <td colspan="5"><b><font size="2" face="serif">TAKE-TWO INTERACTIVE
    SOFTWARE, INC.</font></b></td>
</tr>
<tr align="center" valign="top" bgcolor="#ffffff">
  <td colspan="5"><hr size="1" noshade>
    </td>
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  <td colspan="5"><font size="2" face="serif">(Exact name of registrant
    as specified in its charter)</font></td>
  </tr>
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  <td align="left">&nbsp;</td>
  <td align="right">&nbsp;</td>
  <td align="right">&nbsp;</td>
  <td align="right">&nbsp;</td>
  <td align="right">&nbsp;</td>
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<td width="32%" align="left"><div align="center"><b><font size="2" face="serif">Delaware</font></b></div></td>
<td width="0%" align="right">&nbsp;</td>
<td width="32%" align="right"><div align="center"><b><font size="2" face="serif">0-29230</font></b></div></td>
<td width="0%" align="right">&nbsp;</td>
<td width="32%" align="right"><div align="center"><b><font size="2" face="serif">51-0350842</font></b></div></td>
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    </td>
  <td width="0%" align="center">&nbsp;</td>
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  <td width="0%" align="center">&nbsp;</td>
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<td width="32%" align="left"><div align="center"><font size="2" face="serif">(State or Other</font></div></td>
<td width="0%" align="center">&nbsp;</td>
<td width="32%" align="center"><div align="center"><font size="2" face="serif">(Commission</font></div></td>
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<td width="32%" align="center"><div align="center"><font size="2" face="serif">(IRS Employer</font></div></td>
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<td width="32%" align="left"><div align="center"><font size="2" face="serif">Jurisdiction of</font></div></td>
<td width="0%" align="center">&nbsp;</td>
<td width="32%" align="center"><div align="center"><font size="2" face="serif">File Number)</font></div></td>
<td width="0%" align="center">&nbsp;</td>
<td width="32%" align="center"><div align="center"><font size="2" face="serif">Identification No.)</font></div></td>
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<td width="32%" align="left"><div align="center"><font size="2" face="serif">Incorporation)</font></div></td>
<td width="0%" align="left">&nbsp;</td>
<td width="32%" align="left"><div align="center"><font size="2" face="serif">&nbsp;</font></div></td>
<td width="0%" align="left">&nbsp;</td>
<td width="32%" align="left"><div align="center"><font size="2" face="serif">&nbsp;</font></div></td>
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<br><br>
<table width="100%" cellspacing="0" cellpadding="0" align="center" border="0">
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<td width="50%"><b><font size="2" face="serif">622 Broadway, New York, NY</font></b></td>
<td width="50%"><b><font size="2" face="serif">10012</font></b></td>
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<td width="50%"><font size="2" face="serif">(Address of Principal Executive Offices)</font></td>
<td width="50%"><font size="2" face="serif">(Zip Code)</font></td>
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<p align="left"><font size="2" face="serif">Registrant&#8217;s telephone number,
    including area code <u><b>(646) 536-2842</b></u></font></p>
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<td align="center"><b><font size="2" face="serif">Not Applicable</font></b></td>
</tr>
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    </td>
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<td align="center"><font size="2" face="serif">(Former Name or Former Address, if Changed Since Last Report)</font></td>
</tr>
</table>
<p align="left"><font size="2" face="serif">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (<i>see </i>General Instruction A.2. below):</font></p>  <table width="100%" cellspacing="0" cellpadding="0" border="0">
<tr valign="top">
<td align="left" width="3%"><img src="emptybox.gif" width="12" height="12"></td>
<td align="left"><font size="2" face="serif">Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)</font></td>
</tr>
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<td width="3%">&nbsp;</td>
<td>&nbsp;</td> </tr>
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<td width="3%" align="left"><img src="emptybox.gif" width="12" height="12"></td>
<td align="left"><font size="2" face="serif">Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)</font></td>
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<td width="3%">&nbsp;</td>
<td>&nbsp;</td> </tr>
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<td width="3%" align="left"><img src="emptybox.gif" width="12" height="12"></td>
<td align="left"><font size="2" face="serif">Pre-commencement communications
    pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))</font></td>
</tr>
<tr valign="top">
<td width="3%">&nbsp;</td>
<td>&nbsp;</td> </tr>
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<td width="3%" align="left"><img src="emptybox.gif" width="12" height="12"></td>
<td align="left"><font size="2" face="serif">Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))</font></td>
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<td align="left"><font size="2" face="serif"><b>ITEM 8.01&nbsp;&nbsp;&nbsp;OTHER
    INFORMATION</b> </font></td>
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<p align="left"><font size="2" face="serif">Ryan A. Brant, who has been employed by Take-Two Interactive Software, Inc. (the &#8220;Company&#8221;) in a non-executive capacity as Vice President of Production, and who has been on disability leave since June 2006, resigned his position of employment with the Company as of the close of business on October 16, 2006.  Mr. Brant founded the Company in 1993, serving as Chief Executive Officer until February 2001 and Chairman until March 2004. </font></p>
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<p align="center"><b><font size="2" face="serif">SIGNATURES</font></b></p>
<div style="text-indent: 3%">
<p align="left"><font size="2" face="serif">Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.</font></p>
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<td width="50%"><font size="2" face="serif">&nbsp;</font></td>
<td align="left"><font size="2" face="serif">TAKE-TWO INTERACTIVE SOFTWARE, INC.</font></td>
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<td width="50%"><font size="2" face="serif">&nbsp;</font></td>
<td align="left"><font size="2" face="serif">(Registrant)</font></td>
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  <td align="left">&nbsp;</td>
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<td align="left" width="5%"><font size="2" face="serif">By: </font></td>
<td align="left"><font size="2" face="serif"> <u>/s/ Paul Eibeler</u></font></td>
</tr>
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  <td width="50%" align="left">&nbsp;</td>
<td align="left"><font size="2" face="serif">&nbsp;</font></td>
<td align="left"><font size="2" face="serif">Name: Paul Eibeler</font></td>
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  <td width="50%" align="left">&nbsp;</td>
<td align="left"><font size="2" face="serif">&nbsp;</font></td>
<td align="left"><font size="2" face="serif">Title:   CEO and President</font></td>
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</table>
<p align="left"><font size="2" face="serif">Date: October 17, 2006</font></p>
<p align="center"><font size="2" face="serif">-2-</font></p>
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Prepared and filed by St Ives Financial
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, DC 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15 (d) of the
Securities Exchange Act of 1934
Date of Report (Date of earliest event reported):
October 16, 2006
TAKE-TWO INTERACTIVE
    SOFTWARE, INC.
(Exact name of registrant
    as specified in its charter)
Delaware
0-29230
51-0350842
(State or Other
(Commission
(IRS Employer
Jurisdiction of
File Number)
Identification No.)
Incorporation)
622 Broadway, New York, NY
10012
(Address of Principal Executive Offices)
(Zip Code)
Registrant's telephone number,
    including area code
(646) 536-2842
Not Applicable
(Former Name or Former Address, if Changed Since Last Report)
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (
see
General Instruction A.2. below):
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
Pre-commencement communications
    pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
ITEM 8.01   OTHER
    INFORMATION
Ryan A. Brant, who has been employed by Take-Two Interactive Software, Inc. (the "Company") in a non-executive capacity as Vice President of Production, and who has been on disability leave since June 2006, resigned his position of employment with the Company as of the close of business on October 16, 2006.  Mr. Brant founded the Company in 1993, serving as Chief Executive Officer until February 2001 and Chairman until March 2004.
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.
TAKE-TWO INTERACTIVE SOFTWARE, INC.
(Registrant)
By:
/s/ Paul Eibeler
Name: Paul Eibeler
Title:   CEO and President
Date: October 17, 2006
-2-