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Prepared and filed by St Ives Financial
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<p align="center"><font size="2" face="serif"><b>UNITED STATES</b></font><br>
<font size="2" face="serif"><b>SECURITIES AND EXCHANGE COMMISSION</b></font><br>
<font size="2" face="serif"><b>Washington, D. C.  20549</b></font></p>
<p align="center"><font size="2" face="serif"><b>___________</b></font></p>
<p align="center"><font size="2" face="serif"><b>FORM 8-K</b></font></p>
<p align="center"><font size="2" face="serif"><b>CURRENT REPORT</b></font></p>
<p align="center"><font size="2" face="serif"><b>Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934</b></font></p>
<p align="center"><font size="2" face="serif"><b>August 28, 2006</b></font><br>
<font size="2" face="serif">Date of report (Date of earliest event reported)</font></p>
<p align="center"><b><font face="serif" size="3">APPLERA CORPORATION</font></b><br>
<font size="2" face="serif">(Exact name of registrant as specified in its charter)</font></p>
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    <td width="33%"><font size="2" face="serif"><b>Delaware</b></font></td>
    <td width="33%"><font size="2" face="serif"><b>1-4389</b></font></td>
    <td><font size="2" face="serif"><b>06-1534213</b></font></td>
  </tr>
  <tr align="center" valign="middle">
    <td><font size="2" face="serif">&nbsp;(State or other jurisdiction<br>
    of Incorporation)    </font></td>
    <td><font size="2" face="serif">&nbsp;(Commission<br>
      file
number)    </font></td>
    <td><font size="2" face="serif">(IRS Employer<br>
    &nbsp;Identification No.)    </font></td>
  </tr>
</table>
<p align="center"><font size="2" face="serif"><b>301 Merritt 7</b></font><br>
<font size="2" face="serif"><b>Norwalk, Connecticut  06851</b></font><br>
<font size="2" face="serif">(Address of Principal Executive
    Offices, Including Zip Code)</font></p>
<p align="center"><font size="2" face="serif"><b>(203) 840-2000</b></font><br>
<font size="2" face="serif">(Registrant&#8217;s telephone number, including area code)</font></p>
<p align="center"><font size="2" face="serif"><b>N/A<br></b>(Former name or former address, if changed since last report)<br></font></p>
<p align="left"><font size="2" face="serif">Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:</font></p>
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<td width="6%"><font size="2" face="serif">&nbsp;<img src="emptybox.gif" width="12" height="12"></font></td>
<td align="left"><font size="2" face="serif">Written communications pursuant
    to Rule 425 under the Securities Act (17 CFR 230.425)</font></td>
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  <td>&nbsp;</td>
  <td align="left">&nbsp;</td>
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<td width="6%"><font size="2" face="serif">&nbsp;<img src="emptybox.gif" width="12" height="12"></font></td>
<td align="left"><font size="2" face="serif">Soliciting material pursuant to
    Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)</font></td>
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  <td>&nbsp;</td>
  <td align="left">&nbsp;</td>
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  <td width="6%"><font size="2" face="serif">&nbsp;<img src="emptybox.gif" width="12" height="12"></font></td>
  <td align="left"><font size="2" face="serif">Pre-commencement communications pursuant to Rule 14d-2(b)
    under the Exchange Act (17 CFR 240.14d-2(b))</font></td>
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  <td width="3%">&nbsp;</td>
  <td align="left">&nbsp;</td>
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<table width="100%" cellspacing="0" cellpadding="0" border="0">
<tr valign="top">
<td width="6%"><font size="2" face="serif">&nbsp;<img src="emptybox.gif" width="12" height="12"></font></td>
<td align="left"><font size="2" face="serif">Pre-commencement communications
    pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))</font></td>
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<p align="center">&nbsp;</p>
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<td><font size="2" face="serif">&nbsp;</font><font size="2" face="serif">&nbsp;</font><font size="2" face="serif"><b>Item
      1.01. Entry into a Material Definitive Agreement.</b></font></td>
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<p align="left"><font size="2" face="serif">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<i>(1)  <u>Amendment to Supplemental Executive Retirement Plan</u>.</i>  On August 28, 2006, Applera Corporation (the &#8220;Company&#8221;) adopted the Applera Corporation Amended and Restated Supplemental Executive Retirement Plan (the &#8220;SERP&#8221;).  The principal purpose of the SERP is to amend and restate the Company&#8217;s existing Supplemental Executive Retirement Plan to provide for lump sum payment options for benefits payable to participants under the SERP, consisting of: (1) a lump sum option, which is a single payment upon retirement representing the entire value of a participant&#8217;s accrued benefit under the SERP, and (2) a deferred lump sum option, which is a reduced monthly annuity payable
as of the first day of each month following retirement for a period of 36, 60, or 120 months, as specified by the participant, followed by payment of a lump sum representing the present value of the remaining payments.  The amounts payable under these lump sum options is the same value, from an actuarial standpoint,  as the normal form of payment under the SERP.  The SERP also includes a number of technical changes to the existing Supplemental Executive Retirement Plan intended to clarify certain language in the plan.</font></p>
<p align="left"><font size="2" face="serif">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The
    following executive officers of the Company participate in the SERP: Catherine
    M. Burzik, Senior Vice President and President, Applied Biosystems Group;
    Barbara J. Kerr, Vice President, Human Resources; Kathy Ordo&ntilde;ez, Senior Vice
    President and President, Celera Genomics Group; William B. Sawch, Senior
    Vice President and General Counsel; and Dennis L. Winger, Senior Vice President
    and Chief Financial Officer.</font></p>
<p align="left"><font size="2" face="serif">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<i>(2)  <u>Amendments to Agreements with Executive Officers</u>.</i>  On August 28, 2006, the Company and Tony L. White, our Chairman, President and Chief Executive Officer, amended the terms of Mr. White&#8217;s employment agreement dated September 12, 1995, as amended, to provide for lump sum payment options consistent with those set forth in the SERP and described above. </font></p>
<p align="left"><font size="2" face="serif">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Also
    on August 28, 2006, the Company amended the terms of Mr. Winger&#146;s employment letter
    dated June 24, 1997, as amended, to provide for lump sum payment options
consistent with those set forth in the SERP and described above.  </font></p>
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<p align="center"><font size="2" face="serif"><b>SIGNATURES</b></font></p>
<p align="left"><font size="2" face="serif">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant
    to the requirements of the Securities Exchange Act of 1934, the registrant
    has duly caused this report to be signed on its behalf by the undersigned
    hereunto duly authorized.</font></p>
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    <td colspan="2"><font size="2" face="serif"><b> APPLERA CORPORATION</b></font></td>
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    <td>&nbsp;</td>
    <td width="5%">&nbsp;</td>
    <td>&nbsp;</td>
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    <td>&nbsp;</td>
    <td><font size="2" face="serif">By:</font></td>
    <td><font size="2" face="serif"><u>/s/ Thomas P. Livingston</u></font></td>
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    <td>&nbsp;</td>
    <td>&nbsp;</td>
    <td><font size="2" face="serif">Thomas P. Livingston</font></td>
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    <td>&nbsp;</td>
    <td>&nbsp;</td>
    <td><font size="2" face="serif">Vice President and Secretary</font></td>
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<p align="left"><font size="2" face="serif">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</font></p>
<p align="left"><font size="2" face="serif">Dated: September 1, 2006</font></p>
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Prepared and filed by St Ives Financial
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D. C.  20549
___________
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
August 28, 2006
Date of report (Date of earliest event reported)
APPLERA CORPORATION
(Exact name of registrant as specified in its charter)
Delaware
1-4389
06-1534213
(State or other jurisdiction
of Incorporation)
(Commission
file
number)
(IRS Employer
Identification No.)
301 Merritt 7
Norwalk, Connecticut  06851
(Address of Principal Executive
    Offices, Including Zip Code)
(203) 840-2000
(Registrant's telephone number, including area code)
N/A
(Former name or former address, if changed since last report)
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
Written communications pursuant
    to Rule 425 under the Securities Act (17 CFR 230.425)
Soliciting material pursuant to
    Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
Pre-commencement communications pursuant to Rule 14d-2(b)
    under the Exchange Act (17 CFR 240.14d-2(b))
Pre-commencement communications
    pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Item
      1.01. Entry into a Material Definitive Agreement.
(1)
Amendment to Supplemental Executive Retirement Plan
.
On August 28, 2006, Applera Corporation (the "Company") adopted the Applera Corporation Amended and Restated Supplemental Executive Retirement Plan (the "SERP").  The principal purpose of the SERP is to amend and restate the Company's existing Supplemental Executive Retirement Plan to provide for lump sum payment options for benefits payable to participants under the SERP, consisting of: (1) a lump sum option, which is a single payment upon retirement representing the entire value of a participant's accrued benefit under the SERP, and (2) a deferred lump sum option, which is a reduced monthly annuity payable
as of the first day of each month following retirement for a period of 36, 60, or 120 months, as specified by the participant, followed by payment of a lump sum representing the present value of the remaining payments.  The amounts payable under these lump sum options is the same value, from an actuarial standpoint,  as the normal form of payment under the SERP.  The SERP also includes a number of technical changes to the existing Supplemental Executive Retirement Plan intended to clarify certain language in the plan.
The
    following executive officers of the Company participate in the SERP: Catherine
    M. Burzik, Senior Vice President and President, Applied Biosystems Group;
    Barbara J. Kerr, Vice President, Human Resources; Kathy Ordoñez, Senior Vice
    President and President, Celera Genomics Group; William B. Sawch, Senior
    Vice President and General Counsel; and Dennis L. Winger, Senior Vice President
    and Chief Financial Officer.
(2)
Amendments to Agreements with Executive Officers
.
On August 28, 2006, the Company and Tony L. White, our Chairman, President and Chief Executive Officer, amended the terms of Mr. White's employment agreement dated September 12, 1995, as amended, to provide for lump sum payment options consistent with those set forth in the SERP and described above.
Also
    on August 28, 2006, the Company amended the terms of Mr. Winger's employment letter
    dated June 24, 1997, as amended, to provide for lump sum payment options
consistent with those set forth in the SERP and described above.
SIGNATURES
Pursuant
    to the requirements of the Securities Exchange Act of 1934, the registrant
    has duly caused this report to be signed on its behalf by the undersigned
    hereunto duly authorized.
APPLERA CORPORATION
By:
/s/ Thomas P. Livingston
Thomas P. Livingston
Vice President and Secretary
Dated: September 1, 2006