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<p style=' margin-bottom:0pt; margin-top:0pt;text-align:center;'><B><font style='font-size:16 PT'>UNITED STATES</font></B></p>

<p style=' margin-bottom:0pt; margin-top:0pt;text-align:center;'><B><font style='font-size:16 PT'>SECURITIES AND EXCHANGE COMMISSION</font></B></p>

<p style=' margin-bottom:0pt; margin-top:0pt;text-align:center;'><b><font style='font-size:10 pt'>Washington, D.C. 20549 </font></b></p>

<p style=' margin-bottom:0pt; margin-top:12pt;text-align:center;'><B><font style='font-size:16 PT'>FORM 8-K </font></B></p>


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<p style=' margin-bottom:0pt; margin-top:12pt;text-align:center;'><B><font style='font-size:10 PT'>CURRENT REPORT</font></B></p>

<p style=' margin-bottom:0pt; margin-top:12pt;text-align:center;'><b><font style='font-size:10 pt'>PURSUANT TO SECTION 13 OR 15(d)</font></b></p>

<p style=' margin-bottom:0pt; margin-top:0pt;text-align:center;'><B><font style='font-size:10 PT'>OF THE SECURITIES EXCHANGE ACT OF 1934 </font></B></p>

<p style=' margin-bottom:0pt; margin-top:12pt;text-align:center;'><b><font style='font-size:10 pt'>November 8, 2006</font></b></p>

<p style=' margin-bottom:0pt; margin-top:0pt;text-align:center;'><b><font style='font-size:10 pt'>Date of Report (Date of Earliest Event Reported)</font></b></p>


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<p style=' margin-bottom:0pt; margin-top:8pt;text-align:center;'><B><font style='font-size:18 PT'>POLYMEDIX, INC.</font></B></p>

<p style=' margin-bottom:0pt; margin-top:0pt;text-align:center;'><font style='font-size:10 pt'>(Exact name of registrant as specified in its charter) </font></p>


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    <td align=center valign=top width="35%"><b><font style='font-size:10 pt'>Delaware</font></b><br>
      <font style='font-size:10 pt'>(State or other jurisdiction</font><br>
      <font style='font-size:10 pt'>of incorporation)</font><br>
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    <td align=center valign=top><b><font style='font-size:10 pt'>000-51895</font></b><br>
      <font style='font-size:10 pt'>(Commission File Number)</font><br>
      <br>
    </td>
    <td align=center valign=top width="35%"><b><font style='font-size:10 pt'>27-0125925</font></b><br>
      <font style='font-size:10 pt'>(IRS Employer</font><br>
      <font style='font-size:10 pt'>Identification No.)</font><br>
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    <td width="3%">&nbsp;</td>
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    <td align=center valign=top><b><font style='font-size:10 pt'>3701 Market Street</font></b><br>
      <b><font style='font-size:10 pt'>Philadelphia, PA</font></b><br>
      <font style='font-size:10 pt'>&nbsp;</font><font style='font-size:10 pt'>(Address
      of principal executive offices)</font><br>
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    <td align=center >&nbsp;</td>
    <td align=center valign=bottom><b><font style='font-size:10 pt'>19104</font></b>
      <br>
      <font style='font-size:10 pt'>(Zip Code)</font></td>
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<p style=' margin-bottom:0pt; margin-top:8pt;text-align:center;'><b><font style='font-size:10 pt'>215-966-6227</font></b></p>

<p style=' margin-bottom:0pt; margin-top:0pt;text-align:center;'><font style='font-size:10 pt'>(Registrant&#146;s telephone number, including area code)</font></p>

<p style=' margin-bottom:0pt; margin-top:8pt;text-align:center;'><b><font style='font-size:10 pt'>Not Applicable</font></b></p>

<p style=' margin-bottom:0pt; margin-top:0pt;text-align:center;'><font style='font-size:10 pt'>(Former name or address, if changed since last report)</font></p>


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<p style=' margin-bottom:0pt; margin-top:8pt;text-align:left;'><font style='font-size:10 pt'>Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:</font></p>


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<p style=' margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt;'><font style='font-size:10 pt'>Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)</font></p> </td> </tr></table>
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<p style=' margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt;'><font style='font-size:10 pt'>Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)</font></p> </td> </tr></table>
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<p style=' margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt;'><font style='font-size:10 pt'>Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))</font></p> </td> </tr></table>
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<p style=' margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt;'><font style='font-size:10 pt'>Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))</font></p> </td> </tr></table>
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        <p style=' margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt;'><b><font style='font-size:10 pt'>Item
          8.01.</font></b></p>
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<p style=' margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt;'><b><font style='font-size:10 pt'>Other Events</font></b></p> </td> </tr></table>
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<p style=' margin-bottom:0pt; margin-top:8pt; margin-left:5%;text-align:left;'><font style='font-size:10 pt'>On November 8, 2006, the Board of Directors of PolyMedix, Inc. (the &#147;Company&#148;) declared a dividend to be payable to the holders of record as of that date of the Company&#146;s issued and outstanding shares of its Series 1 Convertible Preferred Stock (the &#147;Series 1 Stock&#148;) who held their shares as of 11:59 p.m. on December 31, 2005, as provided in the Company&#146;s Certificate of Designations. The dividend is payable in shares of Series 1 Stock, accrued at an annual rate of 6%, or $0.18 per share, and prorated for each holder from the date of each closing of the offering of shares of the Series 1 Stock through December 31, 2005.</font></p>

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<p style=' margin-bottom:0pt; margin-top:8pt;text-align:center;'><B><font style='font-size:10 PT'>SIGNATURE</font></B></p>

<p style=' margin-bottom:0pt; margin-top:8pt;text-align:left;'><font style='font-size:10 pt'>Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.</font></p>

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<p style=' margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0in;margin-bottom:0pt;'><font style='font-size:10 PT'>POLYMEDIX, INC.</font></p> </td> </tr>
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<p style=' margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0in;margin-bottom:0pt;'>  </p> </td>

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<p style=' margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0in;margin-bottom:0pt;'><br> <font style='font-size:10 pt'>/s/ Edward F. Smith</font></p> </td> </tr>
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<p style=' margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0in;margin-bottom:0pt;'><font style='font-size:10 pt'>Edward F. Smith</font><br> <font style='font-size:10 pt'>Vice President, Finance and Chief Financial Officer</font></p> </td> </tr></table>
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<p style=' margin-bottom:0pt; margin-top:8pt;text-align:left;'><font style='font-size:10 pt'>November 10, 2006</font></p>

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{"company-data": {"conformed-name": "POLYMEDIX INC", "cik": "0001341843", "assigned-sic": "2834", "irs-number": "000000000"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "000-51895", "film-number": "061205353"}, "business-address": {"street1": "C/O POLYMEDIX INC", "street2": "3701 MARKET STREET STE 442", "city": "PHILADELPHIA", "state": "PA", "zip": "19104", "phone": "2159666199"}, "mail-address": {"street1": "C/O POLYMEDIX INC", "street2": "3701 MARKET STREET STE 442", "city": "PHILADELPHIA", "state": "PA", "zip": "19104"}, "former-company": {"former-conformed-name": "BTHC II ACQUISITION CORP", "date-changed": "20051019"}}
Prepared and filed by St Ives Financial
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 8-K
CURRENT REPORT
PURSUANT TO SECTION 13 OR 15(d)
OF THE SECURITIES EXCHANGE ACT OF 1934
November 8, 2006
Date of Report (Date of Earliest Event Reported)
POLYMEDIX, INC.
(Exact name of registrant as specified in its charter)
Delaware
(State or other jurisdiction
of incorporation)
000-51895
(Commission File Number)
27-0125925
(IRS Employer
Identification No.)
3701 Market Street
Philadelphia, PA
(Address
      of principal executive offices)
19104
(Zip Code)
215-966-6227
(Registrant's telephone number, including area code)
Not Applicable
(Former name or address, if changed since last report)
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Item
          8.01.
Other Events
On November 8, 2006, the Board of Directors of PolyMedix, Inc. (the "Company") declared a dividend to be payable to the holders of record as of that date of the Company's issued and outstanding shares of its Series 1 Convertible Preferred Stock (the "Series 1 Stock") who held their shares as of 11:59 p.m. on December 31, 2005, as provided in the Company's Certificate of Designations. The dividend is payable in shares of Series 1 Stock, accrued at an annual rate of 6%, or $0.18 per share, and prorated for each holder from the date of each closing of the offering of shares of the Series 1 Stock through December 31, 2005.
SIGNATURE
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
POLYMEDIX, INC.
/s/ Edward F. Smith
Edward F. Smith
Vice President, Finance and Chief Financial Officer
November 10, 2006