<PAGE>

                       SECURITIES AND EXCHANGE COMMISSION

                              Washington, DC 20549



                                    FORM 8-K

                                 CURRENT REPORT



     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934


        Date of Report (Date of earliest event reported): April 20, 2006


                           CommerceFirst Bancorp, Inc.
             (Exact name of registrant as specified in its charter)


          Maryland                        0-51104                    52-2180744
(State or other jurisdiction      (Commission file number)         (IRS Employer
    of incorporation)                                                  Number)


                 1804 West Street, Suite 200, Annapolis MD 21401
               (Address of Principal Executive Offices) (Zip Code)


        Registrant's telephone number, including area code: 410.280.6695

         Check the appropriate box below if the Form 8-K is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions (See General Instruction A.2. below):

|_|  Written communications pursuant to Rule 425 under the Securities Act
     (17 CFR 230.425)

|_|  Soliciting material pursuant to Rule 14a-12 under the Exchange Act
     (17 CFR 240.14a-12)

|_|  Pre-commencement communications pursuant to Rule 14d-2(b) under the
     Exchange Act (17 CFR 240.14d-2(b))

|_|  Pre-commencement communications pursuant to Rule 13e-4(c) under the
     Exchange Act (17 CFR 240.13e-4(c))

<PAGE>

Item 2.02  Results of Operations and Financial Condition
Item 7.01  Regulation FD Disclosure

         On April 20, 2006, CommerceFirst Bancorp issued the press release
attached as exhibit 99.

Item 9.01  Financial Statements and Exhibits

(a)  Financial Statements of Business Acquired.  Not applicable.

(b) Pro Forma Financial Information. Not applicable.

(c) Shell Company Transactions. Not applicable.

(d) Exhibits.

         99       Press Release dated April 20, 2006



                                   Signatures


         Pursuant to the requirements of the Securities Exchange Act of 1934,
the registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.


                             COMMERCEFIRST  BANCORP, INC.



                             By: /s/ Lamont Thomas
                                ------------------------------------------------
                                Lamont Thomas, Executive Vice President, Chief
                                Operating Officer

Dated: May 1, 2006
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{"company-data": {"conformed-name": "COMMERCEFIRST BANCORP INC", "cik": "0001098813", "assigned-sic": "6021", "irs-number": "522180744", "state-of-incorporation": "MD", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "000-51104", "film-number": "06794295"}, "business-address": {"street1": "1804 WEST STREET", "street2": "SUITE 200", "city": "ANNAPOLIS", "state": "MD", "zip": "21404", "phone": "4102806695"}, "mail-address": {"street1": "1804 WEST STREET", "street2": "SUITE 200", "city": "ANNAPOLIS", "state": "MD", "zip": "21404"}}
SECURITIES AND EXCHANGE COMMISSION

                              Washington, DC 20549

                                    FORM 8-K

                                 CURRENT REPORT

     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

        Date of Report (Date of earliest event reported): April 20, 2006

                           CommerceFirst Bancorp, Inc.
             (Exact name of registrant as specified in its charter)

          Maryland                        0-51104                    52-2180744
(State or other jurisdiction      (Commission file number)         (IRS Employer
    of incorporation)                                                  Number)

                 1804 West Street, Suite 200, Annapolis MD 21401
               (Address of Principal Executive Offices) (Zip Code)

        Registrant's telephone number, including area code: 410.280.6695

         Check the appropriate box below if the Form 8-K is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions (See General Instruction A.2. below):

|_|  Written communications pursuant to Rule 425 under the Securities Act
     (17 CFR 230.425)

|_|  Soliciting material pursuant to Rule 14a-12 under the Exchange Act
     (17 CFR 240.14a-12)

|_|  Pre-commencement communications pursuant to Rule 14d-2(b) under the
     Exchange Act (17 CFR 240.14d-2(b))

|_|  Pre-commencement communications pursuant to Rule 13e-4(c) under the
     Exchange Act (17 CFR 240.13e-4(c))
Item 2.02  Results of Operations and Financial Condition
Item 7.01  Regulation FD Disclosure

         On April 20, 2006, CommerceFirst Bancorp issued the press release
attached as exhibit 99.

Item 9.01  Financial Statements and Exhibits

(a)  Financial Statements of Business Acquired.  Not applicable.

(b) Pro Forma Financial Information. Not applicable.

(c) Shell Company Transactions. Not applicable.

(d) Exhibits.

         99       Press Release dated April 20, 2006

                                   Signatures

         Pursuant to the requirements of the Securities Exchange Act of 1934,
the registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                             COMMERCEFIRST  BANCORP, INC.

                             By: /s/ Lamont Thomas
                                ------------------------------------------------
                                Lamont Thomas, Executive Vice President, Chief
                                Operating Officer

Dated: May 1, 2006