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Prepared and filed by St Ives Financial
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<p align="center"><font size="2" face="serif"><b><font size="4">United States<br>
Securities and Exchange Commission</font><br>
Washington, D.C. 20549</b></font></p>
<p align="center"><font size="4" face="serif"><b>Form 8-K</b></font></p>
<p align="center"><font size="2" face="serif"><b>Current Report</b></font><br>
<font size="2" face="serif"><b>Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934</b></font></p>  <table width="100%" cellspacing="0" cellpadding="0" border="0">
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<td align="center"><font size="2" face="serif"><b>July 25, 2006</b></font></td>
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<td align="center"><font size="2" face="serif">Date of Report (Date of earliest event reported)</font></td>
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<td align="center"><font size="2" face="serif"><b>POLYMEDIX, INC.</b></font></td>
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<td align="center"><font size="2" face="serif">(Exact name of registrant as specified in its charter)</font></td>
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<td width="30%"><font size="2" face="serif"><b>Delaware</b></font></td>
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<td width="30%"><font size="2" face="serif"><b>000-51895</b></font></td>
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<td><font size="2" face="serif"><b>27-0125925</b></font></td>
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<td><font size="2" face="serif">(State or other jurisdiction <br>of incorporation)</font></td>
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<td><font size="2" face="serif">(Commission File Number)</font></td>
<td>&nbsp;</td>
<td><font size="2" face="serif">(IRS Employer <br>Identification No.)</font></td>
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<td><font size="2" face="serif"><b>3701 Market Street</b></font><br>
  <font size="2" face="serif"><b>Philadelphia, PA</b></font></td>
<td width="5%">&nbsp;</td>
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<td width="30%"><font size="2" face="serif"><b>19104</b></font></td>
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<td height="19"><font size="2" face="serif">(Address of principal executive offices)</font></td>
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<td><font size="2" face="serif">(Zip Code)</font></td>
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<td align="center"><font size="2" face="serif"><b>(215) 966-6227</b></font></td>
<td align="left" width="2%">&nbsp;</td> </tr>
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<td align="center"><font size="2" face="serif">(Registrant&#8217;s telephone number, including area code)</font></td>
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<td align="center"><font size="2" face="serif"><b>Not Applicable</b></font></td>
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<td align="center"><font size="2" face="serif">(Former name or former address, if changed since last report)</font></td>
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<p align="left"><font size="2" face="serif">Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:<br></font></p>
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<td align="left"><font size="2" face="serif">Written communication pursuant to Rule 425 under the Securities Act (17 CFR 230.425)<br></font></td>
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<td align="left"><img src="emptybox.gif"></td>
<td align="left"><font size="2" face="serif">Soliciting materials pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)<br></font></td>
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<td align="left"><font size="2" face="serif"><img src="emptybox.gif"></font></td>
<td align="left"><font size="2" face="serif">Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))<br></font></td>
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<td align="left"><font size="2" face="serif">Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13-4(c))</font></td>
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<p align="left"><font size="2" face="serif"><b>Item&nbsp;8.01 &nbsp;&nbsp;Other Events.</b></font></p>
<p align="left"><font size="2" face="serif">On July 25, 2006, PolyMedix, Inc. (the &#8220;Company&#8221;) announced that its common stock began trading on the Over-The-Counter Bulletin Board (&#8220;OTC&#8221;) under the symbol PYMX. The Company completed all necessary filings and received clearance from both the Securities Exchange Commission and National Association of Securities Dealers.</font></p>
<p align="left"><font size="2" face="serif">A copy of the press release announcing the commencement of trading of the Company&#8217;s common stock on the OTC is attached as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference.</font></p>
<p align="left"><font size="2" face="serif"><b>Item 9.01 &nbsp;&nbsp;Financial Statements and Exhibits.</b></font></p>
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<td width="3%" align="center"><font size="2" face="serif"><b>(d)</b></font></td>
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<td width="89%" align="left"><font size="2" face="serif"><b>Exhibits</b></font></td>
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<td width="3%" align="center"><font size="2" face="serif">99.1</font></td>
<td width="1%" align="right">&nbsp;</td>
<td align="left"><font size="2" face="serif">Press Release, dated July 25, 2006, issued by PolyMedix, Inc.</font></td>
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<p align="center"><font size="2" face="serif"><b>Signature</b></font></p>
<p align="left"><font size="2" face="serif">Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed by is behalf by the undersigned hereunto duly authorized.</font></p>
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<td width="50%"><font size="2" face="serif">&nbsp;</font></td>
<td width="3%"><font size="2" face="serif">&nbsp;</font></td>
<td align="left"><font size="2" face="serif"><b>POLYMEDIX, INC.</b></font></td>
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<td width="3%"><font size="2" face="serif">&nbsp;</font></td>
<td width="3%"><font size="2" face="serif">By:</font></td>
<td align="left"><font size="2" face="serif">  /s/  Edward Smith</font></td>
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  <td>&nbsp;</td>
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<td align="left"><font size="2" face="serif">Edward Smith</font></td>
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<td width="3%"><font size="2" face="serif">&nbsp;</font></td>
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<td align="left"><font size="2" face="serif">Vice President, Finance and Chief Financial Officer</font></td>
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<p align="left"><font size="2" face="serif">Dated: July 31, 2006</font></p>
<p align="center"><font face="serif" size="2">3</font></p>
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<p align="center"><font size="2" face="serif"><b><u>Exhibit Index</u></b></font></p>
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<td width="12%" align="center" valign="bottom"><font size="2" face="serif"><b>Exhibit No. </b></font></td>
<td align="left" width="2%">&nbsp;</td>
<td width="80%" align="left"><font size="2" face="serif">&nbsp;</font></td>
<td width="2%" align="left">&nbsp;</td> </tr>
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<td width="12%" align="center" valign="bottom"><font size="2" face="serif">99.1</font></td>
<td align="left">&nbsp;</td>
<td align="left" valign="bottom"><font size="2" face="serif">Press Release, dated July 30, 2006, issued by PolyMedix, Inc.</font></td>
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Prepared and filed by St Ives Financial
United States
Securities and Exchange Commission
Washington, D.C. 20549
Form 8-K
Current Report
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
July 25, 2006
Date of Report (Date of earliest event reported)
POLYMEDIX, INC.
(Exact name of registrant as specified in its charter)
Delaware
000-51895
27-0125925
(State or other jurisdiction
of incorporation)
(Commission File Number)
(IRS Employer
Identification No.)
3701 Market Street
Philadelphia, PA
19104
(Address of principal executive offices)
(Zip Code)
(215) 966-6227
(Registrant's telephone number, including area code)
Not Applicable
(Former name or former address, if changed since last report)
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
Written communication pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
Soliciting materials pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13-4(c))
Item 8.01   Other Events.
On July 25, 2006, PolyMedix, Inc. (the "Company") announced that its common stock began trading on the Over-The-Counter Bulletin Board ("OTC") under the symbol PYMX. The Company completed all necessary filings and received clearance from both the Securities Exchange Commission and National Association of Securities Dealers.
A copy of the press release announcing the commencement of trading of the Company's common stock on the OTC is attached as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference.
Item 9.01   Financial Statements and Exhibits.
(d)
Exhibits
99.1
Press Release, dated July 25, 2006, issued by PolyMedix, Inc.
Signature
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed by is behalf by the undersigned hereunto duly authorized.
POLYMEDIX, INC.
By:
/s/  Edward Smith
Edward Smith
Vice President, Finance and Chief Financial Officer
Dated: July 31, 2006
3
Exhibit Index
Exhibit No.
99.1
Press Release, dated July 30, 2006, issued by PolyMedix, Inc.