<html>
<head><title>
Prepared and filed by St Ives Financial
</title>
</head>
<body bgcolor="#FFFFFF">
<div style="page-break-before:always"></div>
<page>
<table width="100%" border="0" cellspacing="0" cellpadding="0">
  <tr>
    <td height="4" valign="bottom" bgcolor="#000000"></td>
  </tr>
  <tr>
    <td height="2" valign="top"></td>
  </tr>
  <tr>
    <td height="1" valign="top" bgcolor="#000000"></td>
  </tr>
</table>
<p align="center"><font size="2" face="serif"><b>UNITED STATES<br>
SECURITIES AND EXCHANGE COMMISSION<br>
Washington, D.C.  20549</b></font></p>
<p align="center"><font size="2" face="serif"><b>___________</b></font></p>
<p align="center"><font size="2" face="serif"><b>FORM 8-K</b></font></p>
<p align="center"><font size="2" face="serif"><b>CURRENT REPORT</b></font></p>
<p align="center"><font size="2" face="serif"><b>Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934</b></font></p>
<p align="center"><font size="2" face="serif"><b>July 27, 2006</b></font><br>
<font size="2" face="serif">Date of Report (Date of earliest event reported)</font></p>
<p align="center"><b><font face="serif" size="3">APPLERA CORPORATION</font></b><br>
<font size="2" face="serif">(Exact Name of Registrant as Specified in Its Charter)</font></p>
<table width="100%" border="0" align="center" cellpadding="0" cellspacing="0">
<tr valign="top" bgcolor="#ffffff">
<td align="center"><font size="2" face="serif"><b>        Delaware</b></font></td>
<td width="5%" align="left">&nbsp;</td>
<td width="30%" align="center"><font size="2" face="serif"><b>       1-4389</b></font></td>
<td width="5%" align="left">&nbsp;</td>
<td width="30%" align="center"><font size="2" face="serif"><b>           06-1534213</b></font></td>
</tr>
<tr valign="top" bgcolor="#FFFFFF">
<td align="center"><font size="2" face="serif">            (State or Other Jurisdiction<br>
  of Incorporation)</font></td>
<td align="left">&nbsp;</td>
<td align="center"><font size="2" face="serif">      (Commission <br>
  File No.)</font></td>
<td align="left">&nbsp;</td>
<td align="center"><font size="2" face="serif">             (IRS Employer<br>
  Identification No.)  </font></td>
</tr>
</table>
<br>
<table width="100%" cellspacing="0" cellpadding="0" border="0">
<tr valign="top">
<td align="center"><font size="2" face="serif"><b>301 Merritt 7</b></font></td>
</tr>
<tr valign="top">
<td align="center"><font size="2" face="serif"><b>Norwalk, Connecticut  06851</b></font></td>
</tr>
<tr valign="top">
<td align="center"><font size="2" face="serif">(Address of Principal Executive Offices, Including Zip Code)</font></td>
</tr>
</table>
<br>
<table width="100%" cellspacing="0" cellpadding="0" align="center" border="0">
<tr valign="top" bgcolor="#ffffff">
<td align="center" valign="bottom"><font size="2" face="serif"><b>(203) 840-2000</b></font></td>
<td align="left" width="2%">&nbsp;</td> </tr>
<tr valign="top" bgcolor="#FFFFFF">
<td align="center"><font size="2" face="serif">(Registrant&#8217;s telephone number, including area code)</font></td>
<td align="left">&nbsp;</td>
</tr>
</table>
<br>
<table width="100%" cellspacing="0" cellpadding="0" border="0">
<tr valign="top">
<td align="center"><font size="2" face="serif"><b>N/A</b></font></td>
</tr>
<tr valign="top">
<td align="center"><font size="2" face="serif">(Former name or former address, if changed since last report)</font></td>
</tr>
</table>
<p align="left"><font size="2" face="serif">Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:</font></p>
<table width="100%" cellspacing="0" cellpadding="0" border="0">
<tr valign="top">
<td align="left" width="5%"><img src="emptybox.gif" width="12" height="12"></td>
<td align="left"><font size="2" face="serif">Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)</font></td>
</tr>
<tr valign="top">
  <td align="left">&nbsp;</td>
  <td align="left">&nbsp;</td>
</tr>
<tr valign="top">
<td width="5%" align="left"><img src="emptybox.gif" width="12" height="12"></td>
<td align="left"><font size="2" face="serif">Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)</font></td>
</tr>
<tr valign="top">
  <td align="left">&nbsp;</td>
  <td align="left">&nbsp;</td>
</tr>
<tr valign="top">
<td width="5%" align="left"><img src="emptybox.gif" width="12" height="12"></td>
<td align="left"><font size="2" face="serif">Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))</font></td>
</tr>
<tr valign="top">
  <td align="left">&nbsp;</td>
  <td align="left">&nbsp;</td>
</tr>
<tr valign="top">
<td width="5%" align="left"><img src="emptybox.gif" width="12" height="12"></td>
<td align="left"><font size="2" face="serif">Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))</font></td>
</tr>
</table>
<p align="center">&nbsp;</p>
<table width="100%" border="0" cellspacing="0" cellpadding="0">
  <tr>
    <td height="1" valign="top" bgcolor="#000000"></td>
  </tr>
  <tr>
    <td height="2" valign="top" bgcolor="#FFFFFF"></td>
  </tr>
  <tr>
    <td height="4" valign="bottom" bgcolor="#000000"></td>
  </tr>
</table>
<div style="page-break-before:always"></div>
<page>
<a name="p?"></a>
<p><a href="#contents"><font size="2">Back to Contents</font></a></p>
<p align="left"><font size="2" face="serif"><b>Item 2.02.  Results of Operations and Financial Condition.</b></font></p>
<p align="left"><font size="2" face="serif">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; On July 27, 2006, Applera Corporation (&#8220;Applera&#8221;) announced financial results for Applera and its business units for the fourth quarter of its 2006 fiscal year and for its full 2006 fiscal year.  Attached hereto as Exhibit 99.1 and incorporated by reference herein is the text of a press release issued on July 27, 2006, with respect to financial results for the fourth quarter of fiscal year 2006 and the full 2006 fiscal year of Applera and Applera&#8217;s Applied Biosystems Group, and attached hereto as Exhibit 99.2 and incorporated by reference herein is the text of a press release issued on July 27, 2006, with respect to financial results for the fourth quarter of fiscal
year 2006 and the full 2006 fiscal year of Applera and Applera&#8217;s Celera Genomics Group.  </font></p>
<p align="left"><font size="2" face="serif"><b>Item 9.01.  Financial Statements and Exhibits.</b></font></p>
<p align="left"><font size="2" face="serif">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<b><i>(c) Exhibits.</i></b></font></p>
<p align="left"><font size="2" face="serif">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The following exhibits are filed with this Report:</font></p>
<table width="100%" border="0" align="center" cellpadding="0" cellspacing="0">
<tr valign="top" bgcolor="#FFFFFF">
<td align="center"><font size="2" face="serif"><i>Exhibit No.</i></font></td>
<td align="left">&nbsp;</td>
<td align="left"><font size="2" face="serif"><i>Description</i></font></td>
</tr>
<tr valign="top">
<td align="center"><font size="2" face="serif">&nbsp;</font></td>
<td align="left">&nbsp;</td>
<td align="left"><font size="2" face="serif">&nbsp;</font></td>
</tr>
<tr valign="top" bgcolor="#ffffff">
<td width="12%" align="center"><font size="2" face="serif">99.1</font></td>
<td width="2%" align="left">&nbsp;</td>
<td align="left"><font size="2" face="serif">Press Release issued July 27, 2006, with respect to financial results for Applera and Applera&#8217;s Applied Biosystems Group.</font></td>
</tr>
<tr valign="top">
<td align="center"><font size="2" face="serif">&nbsp;</font></td>
<td align="left">&nbsp;</td>
<td align="left"><font size="2" face="serif">&nbsp;</font></td>
</tr>
<tr valign="top" bgcolor="#FFFFFF">
<td align="center"><font size="2" face="serif">99.2</font></td>
<td align="left">&nbsp;</td>
<td align="left"><font size="2" face="serif">Press Release issued July 27, 2006, with respect to financial results for Applera and Applera&#8217;s Celera Genomics Group.</font></td>
</tr>
</table>
<p align="center">&nbsp;</p>
<hr noshade align="center" width="100%" size="2">
<div style="page-break-before:always"></div>
<page>
<a name="p?"></a>
<p><a href="#contents"><font size="2">Back to Contents</font></a></p>
<p align="center"><font size="2" face="serif"><b>SIGNATURES</b></font></p>
<p align="left"><font size="2" face="serif">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.</font></p>

<table width="100%" border="0" cellpadding="0" cellspacing="0">
<tr valign="top">
  <td align="left">&nbsp;</td>
  <td colspan="2" align="left"><font size="2" face="serif">&nbsp;</font><font size="2" face="serif"><b>APPLERA CORPORATION</b></font></td>
</tr>
<tr valign="top">
  <td align="left">&nbsp;</td>
  <td align="left"><font size="2" face="serif">&nbsp;</font></td>
<td align="left"><font size="2" face="serif">&nbsp;</font></td> </tr>
<tr valign="top">
  <td width="50%" align="left">&nbsp;</td>
<td width="5%" align="left"><font size="2" face="serif">By: </font></td>
<td align="left"><font size="2" face="serif">/s/ Dennis L. Winger</font></td>
</tr>
<tr valign="top">
  <td></td>
<td></td>
<td><hr align="left" width="50%" size="1" noshade></td>
</tr>
<tr valign="top">
  <td align="left">&nbsp;</td>
<td align="left"><font size="2" face="serif">&nbsp;</font></td>
<td align="left"><font size="2" face="serif">Dennis L. Winger</font></td>
</tr>
<tr valign="top">
  <td align="left">&nbsp;</td>
<td align="left"><font size="2" face="serif">&nbsp;</font></td>
<td align="left"><font size="2" face="serif">Senior Vice President and</font></td>
</tr>
<tr valign="top">
  <td align="left">&nbsp;</td>
<td align="left"><font size="2" face="serif">&nbsp;</font></td>
<td align="left"><font size="2" face="serif">Chief Financial Officer</font></td>
</tr>
</table>
<p align="left"><font size="2" face="serif">Dated: July 27, 2006</font></p>
<p align="center">&nbsp;</p>
<hr noshade align="center" width="100%" size="2">
<div style="page-break-before:always"></div>
<page>
<a name="p?"></a>
<p><a href="#contents"><font size="2">Back to Contents</font></a></p>
<p align="center"><font size="2" face="serif"><b>EXHIBIT INDEX</b></font></p>
<table width="100%" border="0" align="center" cellpadding="0" cellspacing="0">
<tr valign="top" bgcolor="#FFFFFF">
<td align="center"><font size="2" face="serif"><i>Exhibit No.</i></font></td>
<td align="left">&nbsp;</td>
<td align="left"><font size="2" face="serif"><i>Description</i></font></td>
</tr>
<tr valign="top">
<td align="center"><font size="2" face="serif">&nbsp;</font></td>
<td align="left">&nbsp;</td>
<td align="left"><font size="2" face="serif">&nbsp;</font></td>
</tr>
<tr valign="top" bgcolor="#ffffff">
<td width="12%" align="center"><font size="2" face="serif">99.1</font></td>
<td width="2%" align="left">&nbsp;</td>
<td align="left"><font size="2" face="serif">Press Release issued July 27, 2006, with respect to financial results for Applera and Applera&#8217;s Applied Biosystems Group.</font></td>
</tr>
<tr valign="top">
<td align="center"><font size="2" face="serif">&nbsp;</font></td>
<td align="left">&nbsp;</td>
<td align="left"><font size="2" face="serif">&nbsp;</font></td>
</tr>
<tr valign="top" bgcolor="#FFFFFF">
<td align="center"><font size="2" face="serif">99.2</font></td>
<td align="left">&nbsp;</td>
<td align="left"><font size="2" face="serif">Press Release issued July 27, 2006, with respect to financial results for Applera and Applera&#8217;s Celera Genomics Group.</font></td>
</tr>
</table>
<p align="center">&nbsp;</p>
<hr noshade align="center" width="100%" size="2">
</body>
</html>
[{"type": "8-K", "sequence": "1", "filename": "b414182_8k.htm", "description": "FORM 8-K", "secsgml_size_bytes": 11923}]
{"company-data": {"conformed-name": "APPLERA CORP", "cik": "0000077551", "assigned-sic": "3826", "irs-number": "061534213", "state-of-incorporation": "DE", "fiscal-year-end": "0630"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "001-04389", "film-number": "06983222"}, "business-address": {"street1": "301 MERRITT 7", "city": "NORWALK", "state": "CT", "zip": "06851", "phone": "2038402000"}, "mail-address": {"street1": "301 MERRITT 7", "city": "NORWALK", "state": "CT", "zip": "06851"}, "former-company": [{"former-conformed-name": "PE CORP", "date-changed": "19990129"}, {"former-conformed-name": "PERKIN ELMER CORP", "date-changed": "19930601"}]}
Prepared and filed by St Ives Financial
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C.  20549
___________
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
July 27, 2006
Date of Report (Date of earliest event reported)
APPLERA CORPORATION
(Exact Name of Registrant as Specified in Its Charter)
Delaware
1-4389
06-1534213
(State or Other Jurisdiction
of Incorporation)
(Commission
File No.)
(IRS Employer
Identification No.)
301 Merritt 7
Norwalk, Connecticut  06851
(Address of Principal Executive Offices, Including Zip Code)
(203) 840-2000
(Registrant's telephone number, including area code)
N/A
(Former name or former address, if changed since last report)
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Back to Contents
Item 2.02.  Results of Operations and Financial Condition.
(a)      On July 27, 2006, Applera Corporation ("Applera") announced financial results for Applera and its business units for the fourth quarter of its 2006 fiscal year and for its full 2006 fiscal year.  Attached hereto as Exhibit 99.1 and incorporated by reference herein is the text of a press release issued on July 27, 2006, with respect to financial results for the fourth quarter of fiscal year 2006 and the full 2006 fiscal year of Applera and Applera's Applied Biosystems Group, and attached hereto as Exhibit 99.2 and incorporated by reference herein is the text of a press release issued on July 27, 2006, with respect to financial results for the fourth quarter of fiscal
year 2006 and the full 2006 fiscal year of Applera and Applera's Celera Genomics Group.
Item 9.01.  Financial Statements and Exhibits.
(c) Exhibits.
The following exhibits are filed with this Report:
Exhibit No.
Description
99.1
Press Release issued July 27, 2006, with respect to financial results for Applera and Applera's Applied Biosystems Group.
99.2
Press Release issued July 27, 2006, with respect to financial results for Applera and Applera's Celera Genomics Group.
Back to Contents
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
APPLERA CORPORATION
By:
/s/ Dennis L. Winger
Dennis L. Winger
Senior Vice President and
Chief Financial Officer
Dated: July 27, 2006
Back to Contents
EXHIBIT INDEX
Exhibit No.
Description
99.1
Press Release issued July 27, 2006, with respect to financial results for Applera and Applera's Applied Biosystems Group.
99.2
Press Release issued July 27, 2006, with respect to financial results for Applera and Applera's Celera Genomics Group.