<PAGE>

                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                                   -----------

                                    FORM 8-K

                                 CURRENT REPORT
                     PURSUANT TO SECTION 13 OR 15(D) OF THE
                         SECURITIES EXCHANGE ACT OF 1934



Date of Report (Date of earliest event reported)            August 1, 2006
-------------------------------------------------------------------------------


                           ENZON PHARMACEUTICALS, INC.
-------------------------------------------------------------------------------
             (Exact name of registrant as specified in its charter)


    Delaware                     0-12957                    22-2372868
-------------------------------------------------------------------------------
 (State or other          (Commission File No.)      (IRS Identification No.)
 jurisdiction of
  incorporation)


               685 Route 202/206, Bridgewater, New Jersey         08807
-------------------------------------------------------------------------------
                (Address of principal executive offices)       (Zip Code)



Registrant's telephone number, including area code            (908) 541-8600
--------------------------------------------------------------------------------



-------------------------------------------------------------------------------
(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions:
    __
   |__|  Written communication pursuant to Rule 425 under the Securities Act
         (17 CFR 230.425)
    __
   |__|  Soliciting material pursuant to Rule 14a-12 under the Exchange Act
         (17 CFR 240.14a-12)
    __
   |__|  Pre-commencement communication pursuant to Rule 14d-2(b) under the
         Exchange Act (17 CFR 240.14d-2(b)
    __
   |__|  Pre-commencement communication pursuant to Rule 13e-4(c) under the
         Exchange Act (17 CFR 240.13e-4(c))


<PAGE>


ITEM 2.02 RESULTS OF OPERATIONS AND FINANCIAL CONDITION.

On August 1, 2006, Enzon Pharmaceuticals, Inc. ("Enzon") issued a press release
reporting certain financial and other information for the quarter ended June 30,
2006. A copy of Enzon's press release dated August 1, 2006, is attached as
Exhibit 99.1 to this Current Report and is incorporated by reference into this
Item 2.02.

The information in this Item 2.02, including Exhibit 99.1, is being furnished
and shall not be deemed to be "filed" for purposes of Section 18 of the
Securities Exchange Act of 1934 (the "Exchange Act") or otherwise subject to the
liability of that Section, nor shall such information be deemed to be
incorporated by reference into any registration statement or other document
filed under the Securities Act of 1933 or the Exchange Act, except as otherwise
stated in that filing.

ITEM 9.01 FINANCIAL STATEMENTS AND EXHIBITS.

(c) Exhibits.

Exhibit No.    Description

99.1           Press Release of Enzon Pharmaceuticals, Inc. dated August 1, 2006





<PAGE>



                                   SIGNATURES


Pursuant to the requirements of the Securities Exchange Act of 1934, the
Registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

Dated:  August 1, 2006

                                   /s/ Craig A. Tooman
                               By: ____________________________
                                   Craig A. Tooman
                                   Executive Vice President, Finance and Chief
                                   Financial Officer
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UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                                   -----------

                                    FORM 8-K

                                 CURRENT REPORT
                     PURSUANT TO SECTION 13 OR 15(D) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

Date of Report (Date of earliest event reported)            August 1, 2006
-------------------------------------------------------------------------------

                           ENZON PHARMACEUTICALS, INC.
-------------------------------------------------------------------------------
             (Exact name of registrant as specified in its charter)

    Delaware                     0-12957                    22-2372868
-------------------------------------------------------------------------------
 (State or other          (Commission File No.)      (IRS Identification No.)
 jurisdiction of
  incorporation)

               685 Route 202/206, Bridgewater, New Jersey         08807
-------------------------------------------------------------------------------
                (Address of principal executive offices)       (Zip Code)

Registrant's telephone number, including area code            (908) 541-8600
--------------------------------------------------------------------------------

-------------------------------------------------------------------------------
(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions:
    __
   |__|  Written communication pursuant to Rule 425 under the Securities Act
         (17 CFR 230.425)
    __
   |__|  Soliciting material pursuant to Rule 14a-12 under the Exchange Act
         (17 CFR 240.14a-12)
    __
   |__|  Pre-commencement communication pursuant to Rule 14d-2(b) under the
         Exchange Act (17 CFR 240.14d-2(b)
    __
   |__|  Pre-commencement communication pursuant to Rule 13e-4(c) under the
         Exchange Act (17 CFR 240.13e-4(c))
ITEM 2.02 RESULTS OF OPERATIONS AND FINANCIAL CONDITION.

On August 1, 2006, Enzon Pharmaceuticals, Inc. ("Enzon") issued a press release
reporting certain financial and other information for the quarter ended June 30,
2006. A copy of Enzon's press release dated August 1, 2006, is attached as
Exhibit 99.1 to this Current Report and is incorporated by reference into this
Item 2.02.

The information in this Item 2.02, including Exhibit 99.1, is being furnished
and shall not be deemed to be "filed" for purposes of Section 18 of the
Securities Exchange Act of 1934 (the "Exchange Act") or otherwise subject to the
liability of that Section, nor shall such information be deemed to be
incorporated by reference into any registration statement or other document
filed under the Securities Act of 1933 or the Exchange Act, except as otherwise
stated in that filing.

ITEM 9.01 FINANCIAL STATEMENTS AND EXHIBITS.

(c) Exhibits.

Exhibit No.    Description

99.1           Press Release of Enzon Pharmaceuticals, Inc. dated August 1, 2006
SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the
Registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

Dated:  August 1, 2006

                                   /s/ Craig A. Tooman
                               By: ____________________________
                                   Craig A. Tooman
                                   Executive Vice President, Finance and Chief
                                   Financial Officer