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<TITLE> OPKO Health, Inc. (Form: 8-K) </TITLE>
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		UNITED STATES<BR>
	SECURITIES AND EXCHANGE COMMISSION
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	WASHINGTON, D.C. 20549
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	FORM 8-K
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	CURRENT REPORT
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	Pursuant to Section&nbsp;13 or 15(d) of the Securities Exchange Act of 1934
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	Date of Report (Date of Earliest Event Reported):
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	&nbsp;
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	December 30, 2016
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	OPKO Health, Inc.
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<BR>__________________________________________<BR>
	(Exact name of registrant as specified in its charter)
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	Delaware
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	001-33528
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	75-2402409
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_____________________<BR>
	(State or other jurisdiction
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_____________<BR>
	(Commission
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	(I.R.S. Employer
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	of incorporation)
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	File Number)
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	Identification No.)
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	4400 Biscayne Blvd., Miami, Florida
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	33137
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_________________________________<BR>
	(Address of principal executive offices)
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___________<BR>
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	Registrant&#146;s telephone number, including area code:
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	(305) 575-4100
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	Not Applicable
<BR>______________________________________________<BR>
	Former name or former address, if changed since last report
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	&nbsp;
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Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any
of the following provisions:</FONT>
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[&nbsp;&nbsp;]&nbsp;&nbsp;Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)<br>
[&nbsp;&nbsp;]&nbsp;&nbsp;Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)<br>
[&nbsp;&nbsp;]&nbsp;&nbsp;Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))<br>
[&nbsp;&nbsp;]&nbsp;&nbsp;Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))<br>
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<P align="left" style="font-size: 10pt"><FONT style="font-size: 11pt"><B>Item&nbsp;8.01 </B></FONT><FONT style="font-size: 10pt"><B>Other Events.</B>
</FONT>

<P align="left" style="font-size: 10pt; text-indent: 1%">On December&nbsp;30, 2016, OPKO Health, Inc. (the &#147;Company&#148;), a Delaware corporation, issued a
press release announcing an update on the Company&#146;s hGH-CTP clinical programs. A copy of the press
release is attached hereto as Exhibit&nbsp;99.1 and is incorporated herein by reference.


<P align="left" style="font-size: 10pt; text-indent: 1%">On January&nbsp;3, 2017, the &#147;Company determined that its 3.0% Convertible Senior Notes due 2033
(the &#147;Notes&#148;), of which $31.9&nbsp;million is outstanding, continue to be convertible by holders of such
Notes through March&nbsp;31, 2017. The Company has elected to satisfy its conversion obligation under
the Notes in shares of the Company&#146;s common stock. The conversion right has been extended because
the closing price per share of the Company&#146;s common stock has exceeded $9.19, or 130% of the
applicable conversion price of $7.07, for at least 20 of 30 consecutive trading days during the
quarter ended December&nbsp;31, 2016. The Company had previously announced that this conversion right
had been triggered at each of the quarters ended March&nbsp;31, 2015 through December&nbsp;31, 2016. The
Notes will continue to be convertible until March&nbsp;31, 2017, and may be convertible thereafter, if
one or more of the conversion conditions specified in the Indenture, dated as of January&nbsp;30, 2013,
by and between the Company and Wells Fargo Bank N.A. (the &#147;Indenture&#148;), is satisfied during future
measurement periods. Pursuant to the Indenture, a holder who elects to convert the Notes will
receive 141.4827 shares of the Company&#146;s Common Stock plus such number of additional shares as is
applicable on the conversion date per $1,000 principal amount of Notes based on the early
conversion provisions in the Indenture. A complete explanation of the conversion rights of holders
of the Notes, as well as the procedures required to convert the Notes, is set forth in the
Indenture.


<P align="left" style="font-size: 10pt; text-indent: 1%">Wells Fargo Bank, National Association is the trustee for the holders of the Notes and the
conversion agent under the Indenture. Any questions relating to the mechanics of the conversion for
the Notes should be directed to Wells Fargo Bank National Association, Attn: Barry Somrock at
CMESCONVERSIONS@wellsfargo.com.


<P align="left" style="font-size: 10pt"><FONT style="font-size: 11pt"><B>Item&nbsp;9.01 Financial Statements and Exhibits.</B>
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<P align="left" style="font-size: 11pt; text-indent: 4%"><FONT style="font-size: 10pt">(d)&nbsp;Exhibits
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    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Description</DIV></TD>
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    <TD align="right" valign="top">99.1</TD>
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    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Press Release of the Company dated December&nbsp;30, 2016</DIV></TD>
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	SIGNATURES
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	Pursuant to the requirements of the Securities Exchange Act of 1934, the
	registrant has duly caused this report to be signed on its behalf by the
	undersigned hereunto duly authorized.
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	OPKO Health, Inc.
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<I>
	January 3, 2017
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	By:
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<I>
	Steven D. Rubin
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	Name: Steven D. Rubin
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	Title: Executive VP-Administration
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	Exhibit&nbsp;Index
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	Exhibit No.
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	Description
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	99.1
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	&nbsp;
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Press Release of the Company dated December 30, 2016
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OPKO Health, Inc. (Form: 8-K)
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
Date of Report (Date of Earliest Event Reported):
December 30, 2016
OPKO Health, Inc.
__________________________________________
(Exact name of registrant as specified in its charter)
Delaware
001-33528
75-2402409
_____________________
(State or other jurisdiction
_____________
(Commission
______________
(I.R.S. Employer
of incorporation)
File Number)
Identification No.)
4400 Biscayne Blvd., Miami, Florida
33137
_________________________________
(Address of principal executive offices)
___________
(Zip Code)
Registrant's telephone number, including area code:
(305) 575-4100
Not Applicable
______________________________________________
Former name or former address, if changed since last report
Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any
of the following provisions:
[  ]  Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
[  ]  Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
[  ]  Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
[  ]  Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Top of the Form
Item 8.01
Other Events.
On December 30, 2016, OPKO Health, Inc. (the "Company"), a Delaware corporation, issued a
press release announcing an update on the Company's hGH-CTP clinical programs. A copy of the press
release is attached hereto as Exhibit 99.1 and is incorporated herein by reference.
On January 3, 2017, the "Company determined that its 3.0% Convertible Senior Notes due 2033
(the "Notes"), of which $31.9 million is outstanding, continue to be convertible by holders of such
Notes through March 31, 2017. The Company has elected to satisfy its conversion obligation under
the Notes in shares of the Company's common stock. The conversion right has been extended because
the closing price per share of the Company's common stock has exceeded $9.19, or 130% of the
applicable conversion price of $7.07, for at least 20 of 30 consecutive trading days during the
quarter ended December 31, 2016. The Company had previously announced that this conversion right
had been triggered at each of the quarters ended March 31, 2015 through December 31, 2016. The
Notes will continue to be convertible until March 31, 2017, and may be convertible thereafter, if
one or more of the conversion conditions specified in the Indenture, dated as of January 30, 2013,
by and between the Company and Wells Fargo Bank N.A. (the "Indenture"), is satisfied during future
measurement periods. Pursuant to the Indenture, a holder who elects to convert the Notes will
receive 141.4827 shares of the Company's Common Stock plus such number of additional shares as is
applicable on the conversion date per $1,000 principal amount of Notes based on the early
conversion provisions in the Indenture. A complete explanation of the conversion rights of holders
of the Notes, as well as the procedures required to convert the Notes, is set forth in the
Indenture.
Wells Fargo Bank, National Association is the trustee for the holders of the Notes and the
conversion agent under the Indenture. Any questions relating to the mechanics of the conversion for
the Notes should be directed to Wells Fargo Bank National Association, Attn: Barry Somrock at
CMESCONVERSIONS@wellsfargo.com.
Item 9.01 Financial Statements and Exhibits.
(d) Exhibits
Exhibit No.
Description
99.1
Press Release of the Company dated December 30, 2016
Top of the Form
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the
	registrant has duly caused this report to be signed on its behalf by the
	undersigned hereunto duly authorized.
OPKO Health, Inc.
January 3, 2017
By:
Steven D. Rubin
Name: Steven D. Rubin
Title: Executive VP-Administration
Top of the Form
Exhibit Index
Exhibit No.
Description
99.1
Press Release of the Company dated December 30, 2016