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<TITLE> OPKO Health, Inc. (Form: 8-K) </TITLE>
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		UNITED STATES<BR>
	SECURITIES AND EXCHANGE COMMISSION
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	WASHINGTON, D.C. 20549
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	FORM 8-K
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	CURRENT REPORT
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	Pursuant to Section&nbsp;13 or 15(d) of the Securities Exchange Act of 1934
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	Date of Report (Date of Earliest Event Reported):
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	&nbsp;
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	March 23, 2015
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	OPKO Health, Inc.
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<BR>__________________________________________<BR>
	(Exact name of registrant as specified in its charter)
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	Delaware
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	001-33528
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	75-2402409
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_____________________<BR>
	(State or other jurisdiction
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_____________<BR>
	(Commission
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	(I.R.S. Employer
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	of incorporation)
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	File Number)
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	Identification No.)
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	4400 Biscayne Blvd., Miami, Florida
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	33137
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_________________________________<BR>
	(Address of principal executive offices)
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___________<BR>
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	Registrant&#146;s telephone number, including area code:
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	(305) 575-4100
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	Not Applicable
<BR>______________________________________________<BR>
	Former name or former address, if changed since last report
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	&nbsp;
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Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any
of the following provisions:</FONT>
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[&nbsp;&nbsp;]&nbsp;&nbsp;Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)<br>
[&nbsp;&nbsp;]&nbsp;&nbsp;Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)<br>
[&nbsp;&nbsp;]&nbsp;&nbsp;Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))<br>
[&nbsp;&nbsp;]&nbsp;&nbsp;Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))<br>
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<P align="left" style="font-size: 10pt"><FONT style="font-size: 10pt"><B>Item&nbsp;3.02 Unregistered Sales of Equity Securities.</B>
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<P align="left" style="font-size: 10pt; text-indent: 1%">On or around March&nbsp;23, 2015, OPKO Health, Inc. (the &#147;Company&#148;) entered into two exchange
agreements with a holder of the Company&#146;s 3.00% convertible senior notes due 2033 (the &#147;Notes&#148;)
pursuant to which such holder agreed to exchange approximately $36.4&nbsp;million in aggregate principal
amount of Notes for 5,363,896 shares of the Company&#146;s common stock, par value $0.01 per share (the
&#147;Common Stock&#148;) and approximately $168,000 in cash representing accrued interest through the date
of completion of the exchange. The Company expects to complete the exchanges on or around March
27, 2015. This current report on Form 8-K does not constitute an offer to exchange the Notes of
the Company or other securities of the Company for Common Stock of the Company or any other
securities of the Company.


<P align="left" style="font-size: 10pt; text-indent: 1%">The issuance of the shares of the Common Stock in exchange for the Notes are being made in
reliance on the exemption from registration provided in Section&nbsp;3(a)(9) of the Securities Act of
1933, as amended.


<P align="left" style="font-size: 10pt"><B>Forward-Looking Statements</B>


<P align="left" style="font-size: 10pt; text-indent: 1%">The statement above with respect to the anticipated timing of the completion of the exchange
is a forward-looking statement within the meaning of the &#147;safe harbor&#148; provisions of the Private
Securities Litigation Reform Act of 1995. This forward-looking statement is subject to risks and
uncertainties that may cause actual results to differ materially, including the satisfaction of
customary closing conditions and logistics involved in the delivery of the securities being
exchanged. Except as required by law, we do not undertake any obligation to update forward-looking
statements.



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	SIGNATURES
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	Pursuant to the requirements of the Securities Exchange Act of 1934, the
	registrant has duly caused this report to be signed on its behalf by the
	undersigned hereunto duly authorized.
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	OPKO Health, Inc.
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	March 27, 2015
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	By:
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<I>
	Adam Logal
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	Name: Adam Logal
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	Title: Senior Vice President-Chief Financial Officer
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OPKO Health, Inc. (Form: 8-K)
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
Date of Report (Date of Earliest Event Reported):
March 23, 2015
OPKO Health, Inc.
__________________________________________
(Exact name of registrant as specified in its charter)
Delaware
001-33528
75-2402409
_____________________
(State or other jurisdiction
_____________
(Commission
______________
(I.R.S. Employer
of incorporation)
File Number)
Identification No.)
4400 Biscayne Blvd., Miami, Florida
33137
_________________________________
(Address of principal executive offices)
___________
(Zip Code)
Registrant's telephone number, including area code:
(305) 575-4100
Not Applicable
______________________________________________
Former name or former address, if changed since last report
Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any
of the following provisions:
[  ]  Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
[  ]  Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
[  ]  Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
[  ]  Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Top of the Form
Item 3.02 Unregistered Sales of Equity Securities.
On or around March 23, 2015, OPKO Health, Inc. (the "Company") entered into two exchange
agreements with a holder of the Company's 3.00% convertible senior notes due 2033 (the "Notes")
pursuant to which such holder agreed to exchange approximately $36.4 million in aggregate principal
amount of Notes for 5,363,896 shares of the Company's common stock, par value $0.01 per share (the
"Common Stock") and approximately $168,000 in cash representing accrued interest through the date
of completion of the exchange. The Company expects to complete the exchanges on or around March
27, 2015. This current report on Form 8-K does not constitute an offer to exchange the Notes of
the Company or other securities of the Company for Common Stock of the Company or any other
securities of the Company.
The issuance of the shares of the Common Stock in exchange for the Notes are being made in
reliance on the exemption from registration provided in Section 3(a)(9) of the Securities Act of
1933, as amended.
Forward-Looking Statements
The statement above with respect to the anticipated timing of the completion of the exchange
is a forward-looking statement within the meaning of the "safe harbor" provisions of the Private
Securities Litigation Reform Act of 1995. This forward-looking statement is subject to risks and
uncertainties that may cause actual results to differ materially, including the satisfaction of
customary closing conditions and logistics involved in the delivery of the securities being
exchanged. Except as required by law, we do not undertake any obligation to update forward-looking
statements.
Top of the Form
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the
	registrant has duly caused this report to be signed on its behalf by the
	undersigned hereunto duly authorized.
OPKO Health, Inc.
March 27, 2015
By:
Adam Logal
Name: Adam Logal
Title: Senior Vice President-Chief Financial Officer