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		UNITED STATES<BR>
	SECURITIES AND EXCHANGE COMMISSION
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	WASHINGTON, D.C. 20549
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	FORM 8-K
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	CURRENT REPORT
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	Pursuant to Section&nbsp;13 or 15(d) of the Securities Exchange Act of 1934
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	Date of Report (Date of Earliest Event Reported):
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	&nbsp;
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	March 18, 2015
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	OPKO Health, Inc.
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<BR>__________________________________________<BR>
	(Exact name of registrant as specified in its charter)
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	Delaware
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	001-33528
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	75-2402409
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_____________________<BR>
	(State or other jurisdiction
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_____________<BR>
	(Commission
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	(I.R.S. Employer
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	of incorporation)
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	File Number)
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	Identification No.)
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	4400 Biscayne Blvd., Miami, Florida
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	33137
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_________________________________<BR>
	(Address of principal executive offices)
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	&nbsp;
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___________<BR>
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	Registrant&#146;s telephone number, including area code:
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	(305) 575-4100
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	Not Applicable
<BR>______________________________________________<BR>
	Former name or former address, if changed since last report
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	&nbsp;
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Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any
of the following provisions:</FONT>
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[&nbsp;&nbsp;]&nbsp;&nbsp;Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)<br>
[&nbsp;&nbsp;]&nbsp;&nbsp;Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)<br>
[&nbsp;&nbsp;]&nbsp;&nbsp;Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))<br>
[&nbsp;&nbsp;]&nbsp;&nbsp;Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))<br>
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    <TD width="1%" nowrap align="right">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD><FONT style="font-size: 11pt"><B>Item&nbsp;5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of
Certain Officers; Compensatory Arrangements of Certain Officers.</B></FONT></TD>
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<P align="left" style="font-size: 11pt; text-indent: 1%"><FONT style="font-size: 10pt">On March&nbsp;18, 2015, the Compensation Committee of the Board of Directors (the
&#147;<U>Committee</U>&#148;) of OPKO Health, Inc. (the &#147;<U>Company</U>&#148;) held a meeting to review certain
compensation matters for the Company&#146;s executive officers and non-executive employees. At the
meeting, the Committee (i)&nbsp;granted stock options to the Company&#146;s named executive officers (the
&#147;Officers&#148;) to purchase the number of shares of the Company&#146;s common stock set forth opposite their
names below and (ii)&nbsp;approved bonus payments to employees, including the Officers named below in
the amounts set forth opposite their names. The stock options vest ratably over four years and
expire on the tenth anniversary of the grant date.
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    <TD>&nbsp;</TD>
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    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3" style="border-bottom: 1px solid #000000"><B>Stock&nbsp;Options</B></TD>
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    <TD colspan="3" valign="top" align="left"><FONT style="font-size: 10pt">Phillip Frost<BR></FONT></TD>
    <TD>&nbsp;</TD>
    <TD><DIV style="margin-left:10px; text-indent:-10px"><FONT style="font-size: 10pt">Chief Executive
Officer/Chairman</FONT></DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="right"><FONT style="font-size: 10pt"></FONT></TD>
    <TD align="right"><FONT style="font-size: 10pt">500,000</FONT></TD>
    <TD><FONT style="font-size: 10pt"></FONT></TD>
    <TD>&nbsp;</TD>
    <TD align="right"><FONT style="font-size: 10pt">$</FONT></TD>
    <TD align="right"><FONT style="font-size: 10pt">200,000</FONT></TD>
    <TD><FONT style="font-size: 10pt"></FONT></TD>
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    <TD colspan="3" valign="top" align="left"><FONT style="font-size: 10pt">Jane H. Hsiao<BR></FONT></TD>
    <TD>&nbsp;</TD>
    <TD><DIV style="margin-left:10px; text-indent:-10px"><FONT style="font-size: 10pt">Vice Chairman/Chief Technical
Officer</FONT></DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="right"><FONT style="font-size: 10pt"></FONT></TD>
    <TD align="right"><FONT style="font-size: 10pt">450,000</FONT></TD>
    <TD><FONT style="font-size: 10pt"></FONT></TD>
    <TD>&nbsp;</TD>
    <TD align="right"><FONT style="font-size: 10pt">$</FONT></TD>
    <TD align="right"><FONT style="font-size: 10pt">175,000</FONT></TD>
    <TD><FONT style="font-size: 10pt"></FONT></TD>
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    <TD colspan="3" valign="top" align="left"><FONT style="font-size: 10pt">Steven D. Rubin<BR></FONT></TD>
    <TD>&nbsp;</TD>
    <TD><DIV style="margin-left:10px; text-indent:-10px"><FONT style="font-size: 10pt">Executive Vice President</FONT></DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="right"><FONT style="font-size: 10pt"></FONT></TD>
    <TD align="right"><FONT style="font-size: 10pt">450,000</FONT></TD>
    <TD><FONT style="font-size: 10pt"></FONT></TD>
    <TD>&nbsp;</TD>
    <TD align="right"><FONT style="font-size: 10pt">$</FONT></TD>
    <TD align="right"><FONT style="font-size: 10pt">150,000</FONT></TD>
    <TD><FONT style="font-size: 10pt"></FONT></TD>
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    <TD colspan="3" valign="top" align="left"><FONT style="font-size: 10pt">Adam Logal<BR></FONT></TD>
    <TD>&nbsp;</TD>
    <TD><DIV style="margin-left:10px; text-indent:-10px"><FONT style="font-size: 10pt">Senior Vice President/Chief
Financial Officer</FONT></DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="right"><FONT style="font-size: 10pt"></FONT></TD>
    <TD align="right"><FONT style="font-size: 10pt">250,000</FONT></TD>
    <TD><FONT style="font-size: 10pt"></FONT></TD>
    <TD>&nbsp;</TD>
    <TD align="right"><FONT style="font-size: 10pt">$</FONT></TD>
    <TD align="right"><FONT style="font-size: 10pt">100,000</FONT></TD>
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	SIGNATURES
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	Pursuant to the requirements of the Securities Exchange Act of 1934, the
	registrant has duly caused this report to be signed on its behalf by the
	undersigned hereunto duly authorized.
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	OPKO Health, Inc.
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<I>
	March 19, 2015
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	By:
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	Adam Logal
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	Name: Adam Logal
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	Title: Senior Vice President-Chief Financial Officer
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OPKO Health, Inc. (Form: 8-K)
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
Date of Report (Date of Earliest Event Reported):
March 18, 2015
OPKO Health, Inc.
__________________________________________
(Exact name of registrant as specified in its charter)
Delaware
001-33528
75-2402409
_____________________
(State or other jurisdiction
_____________
(Commission
______________
(I.R.S. Employer
of incorporation)
File Number)
Identification No.)
4400 Biscayne Blvd., Miami, Florida
33137
_________________________________
(Address of principal executive offices)
___________
(Zip Code)
Registrant's telephone number, including area code:
(305) 575-4100
Not Applicable
______________________________________________
Former name or former address, if changed since last report
Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any
of the following provisions:
[  ]  Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
[  ]  Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
[  ]  Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
[  ]  Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Top of the Form
Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of
Certain Officers; Compensatory Arrangements of Certain Officers.
On March 18, 2015, the Compensation Committee of the Board of Directors (the
"
Committee
") of OPKO Health, Inc. (the "
Company
") held a meeting to review certain
compensation matters for the Company's executive officers and non-executive employees. At the
meeting, the Committee (i) granted stock options to the Company's named executive officers (the
"Officers") to purchase the number of shares of the Company's common stock set forth opposite their
names below and (ii) approved bonus payments to employees, including the Officers named below in
the amounts set forth opposite their names. The stock options vest ratably over four years and
expire on the tenth anniversary of the grant date.
Name
Title
Stock Options
Bonus
Phillip Frost
Chief Executive
Officer/Chairman
500,000
$
200,000
Jane H. Hsiao
Vice Chairman/Chief Technical
Officer
450,000
$
175,000
Steven D. Rubin
Executive Vice President
450,000
$
150,000
Adam Logal
Senior Vice President/Chief
Financial Officer
250,000
$
100,000
Top of the Form
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the
	registrant has duly caused this report to be signed on its behalf by the
	undersigned hereunto duly authorized.
OPKO Health, Inc.
March 19, 2015
By:
Adam Logal
Name: Adam Logal
Title: Senior Vice President-Chief Financial Officer