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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 18pt; FONT-FAMILY: Times New Roman"><strong>UNITED
      STATES</strong></font></div>
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      AND EXCHANGE COMMISSION</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>Washington,
      D.C. 20549</strong></font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center">______________</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
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      8-K</strong></font></div>
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      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center">______________</div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
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      EXCHANGE ACT OF 1934</strong></font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Date
      of
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      16, 2006</strong></font></div>
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      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center">______________</div>
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      Pharmaceuticals, Inc.</strong></font></div>
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                Byberry Road, Bldg 13</strong></font></div>
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                Valley, Pa </strong></font></div>
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                of Principal Executive Offices)</font></div>
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            <td align="left" valign="bottom" width="1%">&#160;</td>
            <td colspan="3" valign="top" width="35%">
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            <td align="left" valign="middle" width="23%">&#160;</td>
            <td align="left" valign="middle" width="1%">&#160;</td>
            <td align="left" valign="middle" width="11%">&#160;</td>
            <td align="left" valign="middle" width="1%">&#160;</td>
            <td align="left" valign="middle" width="11%">&#160;</td>
            <td align="left" valign="middle" width="1%">&#160;</td>
            <td align="left" valign="middle" width="23%">&#160;</td>
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      914-0900</strong></font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center">
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center">______________</div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
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      the
      appropriate box below if the Form 8-K filing is intended to simultaneously
      satisfy the filing obligation of the registrant under any of the following
      provisions (see General Instruction A.2. below):</font></div>
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                communications pursuant to Rule 425 under the Securities Act (17
                CFR
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                material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
                240.14a-12)</font></div>
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            <td align="left" valign="top" width="4%">
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              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
            </td>
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          <tr>
            <td align="left" valign="top" width="4%">
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            <td align="left" valign="top" width="4%">
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
    <div id="PGBRK" style="MARGIN-LEFT: 0pt; WIDTH: 100%; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt">
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      1.01&#160;&#160;&#160;&#160;&#160;&#160; Entry into a Material Definitive
      Agreement</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 36pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font id="TAB1" style="MARGIN-LEFT: 36pt"></font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Cellegy
      Pharmaceuticals, Inc. (the &#8220;Company&#8221;) has entered into an amendment of its
</font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Exclusive
      License and Distribution Agreement dated as of July 9, 2004, with ProStrakan
      Group plc, which is reflected in a First Amended and Restated Exclusive License
      Agreement dated as of January 16, 2006. The agreement relates to the Company&#8217;s
</font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Tostrex&#174;
      product, which is a 2% topical testosterone gel indicated for the treatment
      of
      male hypogonadism. In December 2004, the product was approved by the Swedish
      Medical Products Agency (MPA) for sale in Sweden.</font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font id="TAB1" style="MARGIN-LEFT: 36pt"></font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Under
      the
      terms of the amended agreement, ProStrakan will assume responsibility for all
      manufacturing and other product support functions and will purchase the product
      directly from the manufacturer rather than purchasing from Cellegy under the
      terms of the original agreement. Cellegy will continue to receive milestone
      payments and royalties as set forth in the original agreement. Cellegy will
      benefit from reduced infrastructure costs by having its partner take over
      manufacturing responsibilities</font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">.</font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 36pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">A
      copy of
      the Company&#8217;s press release relating to the amendment is attached as Exhibit
      99.1 and is incorporated by reference into this Item 1.01.</font></div>
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      9.01 </strong></font><font id="TAB2" style="COLOR: black; LETTER-SPACING: 54pt">&#160;</font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>Financial
      Statements and Exhibits.</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
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                PHARMACEUTICALS, INC.</strong></font></div>
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                January 20, 2006</font></div>
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                Robert J. Caso</font></div>
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Unassociated Document
UNITED
      STATES
SECURITIES
      AND EXCHANGE COMMISSION
Washington,
      D.C. 20549
______________
FORM
      8-K
______________
CURRENT
      REPORT
PURSUANT
      TO SECTION 13 OR 15(d) OF THE
SECURITIES
      EXCHANGE ACT OF 1934
Date
      of
      report (Date of earliest event reported):
January
      16, 2006
______________
Cellegy
      Pharmaceuticals, Inc.
(Exact
      Name of Registrant as Specified in Charter)
Delaware
0-26372
82-0429727
(State
                or other jurisdiction
of
                incorporation)
(Commission
                File Number)
(IRS
                Employer
Identification
                No.)
1800
                Byberry Road, Bldg 13
Huntingdon
                Valley, Pa
19006
(Address
                of Principal Executive Offices)
(Zip
                Code)
Registrant's
      telephone number, including area code:
(215)
      914-0900
Same
(Former
      name or Former Address, if Changed Since Last Report.)
______________
Check
      the
      appropriate box below if the Form 8-K filing is intended to simultaneously
      satisfy the filing obligation of the registrant under any of the following
      provisions (see General Instruction A.2. below):
o
Written
                communications pursuant to Rule 425 under the Securities Act (17
                CFR
                230.425)
o
Soliciting
                material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
                240.14a-12)
o
Pre-commencement
                communications pursuant to Rule 14d-2(b) under the Exchange Act (17
                CFR
                240.14d-2(b))
o
Pre-commencement
                communications pursuant to Rule 13e-4(c) under the Exchange Act (17
                CFR
                240.13e-4(c))
Item
      1.01       Entry into a Material Definitive
      Agreement
Cellegy
      Pharmaceuticals, Inc. (the "Company") has entered into an amendment of its
Exclusive
      License and Distribution Agreement dated as of July 9, 2004, with ProStrakan
      Group plc, which is reflected in a First Amended and Restated Exclusive License
      Agreement dated as of January 16, 2006. The agreement relates to the Company's
Tostrex®
      product, which is a 2% topical testosterone gel indicated for the treatment
      of
      male hypogonadism. In December 2004, the product was approved by the Swedish
      Medical Products Agency (MPA) for sale in Sweden.
Under
      the
      terms of the amended agreement, ProStrakan will assume responsibility for all
      manufacturing and other product support functions and will purchase the product
      directly from the manufacturer rather than purchasing from Cellegy under the
      terms of the original agreement. Cellegy will continue to receive milestone
      payments and royalties as set forth in the original agreement. Cellegy will
      benefit from reduced infrastructure costs by having its partner take over
      manufacturing responsibilities
.
A
      copy of
      the Company's press release relating to the amendment is attached as Exhibit
      99.1 and is incorporated by reference into this Item 1.01.
Item
      9.01
Financial
      Statements and Exhibits.
(c)
      Exhibits
Exhibit
                Number
Description
                of Exhibit
99.1
Press
                Release dated January 19, 2006
SIGNATURE
Pursuant
      to the requirements of the Securities Exchange Act of 1934, the registrant
      has
      duly caused this report to be signed on its behalf by the undersigned hereunto
      duly authorized.
CELLEGY
                PHARMACEUTICALS, INC.
Date:
                January 20, 2006
By:
/s/
                Robert J. Caso
Robert
                J .Caso
Vice
                President, Finance and Chief Financial Officer
(Duly
                Authorized Officer)