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      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>UNITED
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      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 36pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">On
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        shares of its common stock to Cornell Capital Partners, L.P. (&#8220;Cornell&#8221;) under
        the terms of the Standby Equity Distribution Agreement dated September 28,
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        (&#8220;the Agreement&#8221;) currently in effect, for aggregate gross proceeds of $500,000,
        or $1.2653 per share. The per share price was the daily volume weighted average
        price of the Company&#8217;s common stock on December 9, 2005 which was the lowest
        average price during the five trading days following the draw-down notice
        to
        Cornell, as set forth in the Agreement. In connection with the issuance,
        the
        Company paid Cornell a fee of $25,000 and Yorkville Advisors Management,
        LLC a
        fee of $500. The shares were issued pursuant to the exemption from registration
        contained in Section 4(2) of the Securities Act of 1933, as amended, and
        the
        regulations promulgated thereunder, because the shares were issued to a
        sophisticated entity in a private transaction.</font></div>
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        to the requirements of the Securities Exchange Act of 1934, the Registrant
        has
        duly caused this report to be signed on its behalf by the undersigned hereunto
        duly authorized.</font></div>
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              <td colspan="2"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">TITAN
                PHARMACEUTICALS, INC.</font></td>
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              <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">By:&#160;&#160;</font></td>
              <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">/s/ Robert E. Farrell</font></td>
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                <hr style="COLOR: #000000" align="left" noshade size="2" width="80%"><font size="2">Name:
                Robert E. Farrell</font></td>
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              <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Title:
                Chief Financial Officer</font></td>
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        December 15, 2005</font></div>
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{"company-data": {"conformed-name": "TITAN PHARMACEUTICALS INC", "cik": "0000910267", "assigned-sic": "2836", "irs-number": "943171940", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "001-13341", "film-number": "051267846"}, "business-address": {"street1": "400 OYSTER POINT BLVD", "street2": "SUITE 505", "city": "SAN FRANCISCO", "state": "CA", "zip": "94080", "phone": "4152444990"}, "mail-address": {"street1": "400 OYSTER POINT BLVD", "street2": "SUITE 505", "city": "SAN FRANCISCO", "state": "CA", "zip": "94080"}}
UNITED
        STATES
SECURITIES
        AND EXCHANGE COMMISSION
WASHINGTON,
        D.C. 20549
FORM
        8-K
CURRENT
        REPORT
Pursuant
        to Section 13 or 15(d) of
the
        Securities Exchange Act 1934
Date
        of
        Report (Date of earliest event reported): December 13, 2005
Titan
        Pharmaceuticals, Inc.
(Exact
        Name of Registrant as Specified in Charter)
Delaware
0-27436
94-3171940
(State
                  or Other Jurisdiction of Incorporation)
(Commission
                  File Number)
(IRS
                  Employer Identification No.)
400
                      Oyster Point Blvd., Suite 505, South San Francisco, CA
94080
(Address
                      of Principal Executive Offices)
(Zip
                      Code)
Registrant's
                      telephone number, including area code:
650-244-4990
(Former
                        Name or Former Address, is Changed Since Last
                        Report)
Check
        the
        appropriate box below if the Form 8-K filing is intended to simultaneously
        satisfy the filing obligation of registrant under any of the following
        provisions:
o
Written
        communications pursuant to Rule 425 under the Securities Act (17 CFR
        230.425)
o
Soliciting material pursuant to Rule 14a-12(b)
        under the Exchange Act (17 CFR 240.14a-12(b))
o
Pre-commencement communications pursuant to Rule
        14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
o
Pre-commencement communications pursuant to Rule
        13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Item
        3.02.
Unregistered
        Sales of Equity Securities.
On
        December 13, 2005, Titan Pharmaceuticals, Inc. (the "Company") sold 395,163
        shares of its common stock to Cornell Capital Partners, L.P. ("Cornell") under
        the terms of the Standby Equity Distribution Agreement dated September 28,
        2005
        ("the Agreement") currently in effect, for aggregate gross proceeds of $500,000,
        or $1.2653 per share. The per share price was the daily volume weighted average
        price of the Company's common stock on December 9, 2005 which was the lowest
        average price during the five trading days following the draw-down notice
        to
        Cornell, as set forth in the Agreement. In connection with the issuance,
        the
        Company paid Cornell a fee of $25,000 and Yorkville Advisors Management,
        LLC a
        fee of $500. The shares were issued pursuant to the exemption from registration
        contained in Section 4(2) of the Securities Act of 1933, as amended, and
        the
        regulations promulgated thereunder, because the shares were issued to a
        sophisticated entity in a private transaction.
SIGNATURES
Pursuant
        to the requirements of the Securities Exchange Act of 1934, the Registrant
        has
        duly caused this report to be signed on its behalf by the undersigned hereunto
        duly authorized.
TITAN
                PHARMACEUTICALS, INC.
By:
/s/ Robert E. Farrell
Name:
                Robert E. Farrell
Title:
                Chief Financial Officer
Dated:
        December 15, 2005