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    <div><br>&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 14pt; FONT-FAMILY: Times New Roman"><strong>UNITED
      STATES</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 14pt; FONT-FAMILY: Times New Roman"><strong>SECURITIES
      AND EXCHANGE COMMISSION</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 14pt; FONT-FAMILY: Times New Roman"><strong>WASHINGTON,
      DC 20549</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 14pt; FONT-FAMILY: Times New Roman"><strong>FORM
      8-K</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>CURRENT
      REPORT PURSUANT</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>TO
      SECTION 13 OR 15(</strong></font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>d</strong></font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>)
      OF THE</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>SECURITIES
      EXCHANGE ACT OF 1934</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><br></div>
    <div align="center">
      <table bgcolor="white" cellpadding="0" cellspacing="0" width="100%">

          <tr bgcolor="white">
            <td colspan="3" width="75%"><font size="2">Date of report (Date of
              earliest
              event reported): August 14, 2006</font></td>
            <td width="25%">&#160;</td>
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            <td width="25%">&#160;</td>
            <td colspan="2" width="50%">&#160;</td>
            <td width="25%">&#160;</td>
          </tr>
          <tr bgcolor="white">
            <td width="25%">&#160;</td>
            <td colspan="2" width="50%">&#160;</td>
            <td width="25%">&#160;</td>
          </tr>
          <tr bgcolor="white">
            <td width="25%" style="border-bottom: #ffffff solid;">&#160;</td>
            <td colspan="2" width="50%" style="border-bottom: black thin solid;">
              <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><strong><font size="5">eXegenics,
                Inc.</font></strong></div>
            </td>
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              <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font size="2">(Exact
                Name of Registrant as Specified in Its
                Charter)</font></div>
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            <td width="25%">&#160;</td>
            <td width="25%">&#160;</td>
            <td width="25%">&#160;</td>
            <td width="25%">&#160;</td>
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          <tr bgcolor="white">
            <td width="25%">&#160;</td>
            <td colspan="2" width="50%">&#160;</td>
            <td width="25%">&#160;</td>
          </tr>
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            <td width="25%">&#160;</td>
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              <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font size="2">Delaware</font></div>
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            <td width="25%">&#160;</td>
          </tr>
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                or Other Jurisdiction<font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">&#160;</font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">of
                Incorporation)</font></font></div>
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            <td width="25%">&#160;</td>
            <td width="25%">&#160;</td>
            <td width="25%">&#160;</td>
            <td width="25%">&#160;</td>
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            <td width="25%">&#160;</td>
            <td width="25%">&#160;</td>
            <td width="25%">&#160;</td>
            <td width="25%">&#160;</td>
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            <td width="25%" style="border-bottom: black thin solid;">
              <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><strong><font size="2">000-26648</font></strong></div>
            </td>
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            <td width="25%" style="border-bottom: #ffffff solid;">&#160;</td>
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              <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><strong><font size="2">75-2402409</font></strong></div>
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              <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font size="2">(Commission
                File Number)</font></div>
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            <td width="25%">&#160;</td>
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            <td width="55%" style="border-bottom: black thin solid;">
              <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><strong><font size="2">1250
                Pittsford-Victor Road, Building
                200, Suite 280, Pittsford, New York</font></strong></div>
            </td>
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              <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>14534</strong></font></div>
            </td>
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            <td width="55%">
              <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font size="2">(Address
                of Principal Executive
                Offices)</font></div>
            </td>
            <td width="10%">&#160;</td>
            <td width="10%">&#160;</td>
            <td width="25%">
              <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font size="2">(Zip
                Code)</font></div>
            </td>
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          <tr bgcolor="white">
            <td width="55%">&#160;</td>
            <td width="10%">&#160;</td>
            <td width="10%">&#160;</td>
            <td width="25%">&#160;</td>
          </tr>

      </table>
    </div>
    <div>&#160;</div>
    <div align="left">
      <table bgcolor="white" cellpadding="0" cellspacing="0" width="100%">

          <tr bgcolor="white">
            <td width="20%" style="border-bottom: #ffffff solid;">&#160;</td>
            <td colspan="2" width="45%" style="border-bottom: black thin solid;">
              <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><strong><font size="2">(585)
                218-4368</font></strong></div>
            </td>
            <td width="20%" style="border-bottom: #ffffff solid;">&#160;</td>
          </tr>
          <tr bgcolor="white">
            <td width="20%">&#160;</td>
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              <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font size="2">(<font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Registrant&#8217;s
                Telephone Number, Including Area Code)</font></font></div>
            </td>
            <td width="20%">&#160;</td>
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            <td width="20%">&#160;</td>
            <td colspan="2" width="45%">&#160;</td>
            <td width="20%">&#160;</td>
          </tr>
          <tr bgcolor="white">
            <td width="20%" style="border-bottom: #ffffff solid;">&#160;</td>
            <td colspan="2" width="45%" style="border-bottom: black thin solid;">&#160;</td>
            <td width="20%" style="border-bottom: #ffffff solid;">&#160;</td>
          </tr>
          <tr bgcolor="white">
            <td width="20%">&#160;</td>
            <td colspan="2" width="45%">
              <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font size="2">(Former
                Name or Former Address, if Changed Since
                Last Report)</font></div>
            </td>
            <td width="20%">&#160;</td>
          </tr>

      </table>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font id="TAB2" style="COLOR: black; LETTER-SPACING: 225pt"></font>&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><font id="TAB1" style="MARGIN-LEFT: 18pt"></font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Check
      the
      appropriate box below if the Form 8-K filing is intended to simultaneously
      satisfy the filing obligation of the registrant under any of the following
      provisions (</font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><em>see
      </em></font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">General
      Instruction A.2. below):</font></div>
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            <td align="left" style="width: 18pt;"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Wingdings">o</font></td>
            <td align="left" valign="bottom">
              <div align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Written
                communications pursuant to Rule 425 under the Securities Act (17
                CFR
                230.425)</font></div>
            </td>
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      </table>
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          <tr valign="top" style="line-height: 1.25;">
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            <td align="left">&#160;</td>
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      </table>
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            <td align="left" style="width: 18pt;"><font style="DISPLAY: inline; FONT-FAMILY: Wingdings">x</font></td>
            <td align="left"><font size="2">Soliciting material pursuant to Rule
              14a-12
              under the Exchange Act (17 CFR
              240.14a-12)</font>&#160;</td>
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          <tr valign="top" style="line-height: 1.25;">
            <td style="width: 18pt;">&#160;</td>
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              <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Wingdings">o</font></div>
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              <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Pre-commencement
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                CFR
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            </td>
          </tr>

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          <tr valign="top" style="line-height: 1.25;">
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            <td>&#160;</td>
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      </table>
      <table align="center" border="0" cellpadding="0" cellspacing="0" id="hangingindent" width="100%">

          <tr valign="top" style="line-height: 1.25;">
            <td style="width: 18pt;">&#160;</td>
            <td style="width: 18pt;"><font style="FONT-FAMILY: Wingdings" size="2">o</font>&#160;</td>
            <td valign="bottom">
              <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Pre-commencement
                communications pursuant to Rule 13e-4(c) under the Exchange Act (17
                CFR
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      </table>
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    <div>&#160;</div>
    <div>&#160;</div>
    <div>
      <hr style="MARGIN-TOP: -5px; COLOR: #000000" noshade size="1">
      <hr style="MARGIN-TOP: -13px; COLOR: #000000" noshade size="4">
    </div>
    <div id="PGBRK" style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt">
      <div id="FTR">
        <div id="GLFTR" style="WIDTH: 100%" align="left">
        </div>
      </div>
      <div id="PN" style="PAGE-BREAK-AFTER: always">
        <div style="WIDTH: 100%; TEXT-ALIGN: center">
        </div>
        <div style="WIDTH: 100%; TEXT-ALIGN: center">
        </div>
      </div>
      <div id="HDR">
        <div id="GLHDR" style="WIDTH: 100%" align="right">
        </div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>Section
      1 - Registrant&#8217;s Business and Operations</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>Item
      1.01.</strong></font><font id="TAB2" style="COLOR: black; LETTER-SPACING: 9pt">&#160;</font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>Entry
      into a Material Definitive Agreement</strong></font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">&#160;</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">On
      August
      14, 2006, eXegenics, Inc. (the &#8220;Company&#8221;) entered into a Stock Purchase
      Agreement (the &#8220;Purchase Agreement&#8221;) with a group of investors led by Phillip
      Frost, M.D, for the sale of shares of the Company&#8217;s&#160; common stock. The
      shares of common stock to be issued to the purchasers will constitute, upon
      issuance, 51% of the issued and outstanding shares of common stock of the
      Company, on a fully-diluted basis. The aggregate purchase price to be paid
      for
      the shares is $8,613,000, reflecting the book value of the Company at June
      30,
      2006. The purchase price is subject to adjustment based on the book value of
      the
      Company at the closing date. A closing of the stock purchase is subject to
      certain conditions, as more particularly described in the Purchase Agreement.
      Among other things, a closing of the transaction is subject to the approval
      by
      the stockholders of the Company of (i) an amendment to the certificate of
      incorporation of the Company increasing the number of authorized shares of
      common stock and (ii) the consummation of the transaction.</font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">The
      description above is qualified in its entirety by reference to the Stock
      Purchase Agreement which is filed with this Current Report on Form 8-K as
      Exhibit 10.1 and is incorporated herein by reference. </font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">A
      copy of
      the press release announcing the Company&#8217;s execution of the Purchase Agreement
      is filed as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated
      herein by reference.</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-STYLE: italic; FONT-FAMILY: Times New Roman">Addtional
      Information</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify">
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">In
        connection with the proposed sale and issuance of shares of eXegenics common
        stock&#160;and amendment of eXegenics's certificate of incorporation, eXegenics
        will file a proxy statement with the Commission. SECURITY HOLDERS ARE URGED
        TO
        READ THE&#160; PROXY STATEMENT AND ANY OTHER RELEVANT DOCUMENTS TO BE FILED WITH
        THE COMMISSION, WHEN THEY BECOME AVAILABLE BECAUSE THEY WILL CONTAIN IMPORTANT
        INFORMATION. Security holders may obtain a free copy of the proxy statement
        (when available) and other documents filed by eXegenics at the Commission's
        web
        site at www.sec.gov. The&#160; proxy statement and such other documents may also
        be obtained free of charge from eXegenics Inc. by directing such request
        to
        eXegenics Inc., 1250&#160;Pittsford-Victor Road, Building 200, Suite 280,
        Pittsford, New York 14534, tel: (585) 218-4368.</font></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">eXegenics
        and certain of&#160;its directors, executive officers and other members of its
        management and employees may be considered to be soliciting proxies from
        eXegenics stockholders in favor of the proposed sale and issuance of shares
        of
        eXegenics common stock and amendment of eXegenics's certificate of
        incorporation. INFORMATION CONCERNING PERSONS WHO MAY BE CONSIDERED PARTICIPANTS
        IN THE SOLICITATION OF EXEGENICS&#8217; STOCKHOLDERS UNDER THE RULES OF THE COMMISSION
        IS SET FORTH IN THE PROXY STATEMENT FOR THE 2006 ANNUAL MEETING OF EXEGENICS
        INC. FILED BY EXEGENICS WITH THE COMMISSION ON&#160;DECEMBER 13, 2005. Updated
        information concerning these persons will be available in the proxy
        statement.</font></div>
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      7 - Regulation FD</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><br></div>
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      August
      14, 2006, the Company issued a press release related to its execution of the
      Purchase Agreement. A copy of the press release is filed as Exhibit 99.1 to
      this
      Report on form 8-K and is incorporated herein by reference.</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>Section
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>Item
      9.01.</strong></font><font id="TAB2" style="COLOR: black; LETTER-SPACING: 27pt">&#160;</font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>Financial
      Statements and Exhibits</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
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            <td align="left" style="width: 36pt;"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(d)</font></td>
            <td align="left">
              <div align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Exhibits:</font></div>
            </td>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><font id="TAB1" style="MARGIN-LEFT: 36pt"></font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">10.1</font><font id="TAB2" style="COLOR: black; LETTER-SPACING: 27pt">&#160;</font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Stock
      Purchase Agreement dated as of August 14, 2006</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><font id="TAB1" style="MARGIN-LEFT: 36pt"></font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">99.1</font><font id="TAB2" style="COLOR: black; LETTER-SPACING: 27pt">&#160;</font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Press
      Release issued by eXegenics, Inc. dated August 14, 2006.</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
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        <div style="WIDTH: 100%; TEXT-ALIGN: center">
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    <div style="DISPLAY: block; MARGIN-LEFT: 18pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>SIGNATURES</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 18pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 18pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Pursuant
      to the requirements of the Securities Exchange Act of 1934, the registrant
      has
      duly caused this report to be signed on its behalf by the undersigned hereunto
      duly authorized.</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 18pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><br></div>
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            <td width="1%"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">&#160;</font></td>
            <td width="49%"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">&#160;</font></td>
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            <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">&#160;</font></td>
            <td colspan="2"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: "><strong>eXegenics,
              INC.</strong></font></td>
          </tr>
          <tr valign="top" bgcolor="#ffffff">
            <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">&#160;<br>&#160;</font></td>
            <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">&#160;<br>&#160;</font></td>
            <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">&#160;<br>&#160;</font></td>
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          <tr valign="top" bgcolor="#ffffff">
            <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">August
              14, 2006</font></td>
            <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">By:&#160;&#160;</font></td>
            <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">/s/&#160;John
              A.
              Paganelli</font></td>
          </tr>
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            <td align="left">
              <hr style="COLOR: black" align="left" noshade size="2" width="80%"><font size="2">John
              A. Paganelli, Chairman of the Board, Chief Executive
              Officer (Interim) Chief </font></td>
          </tr>
          <tr valign="top" bgcolor="#ffffff">
            <td colspan="2"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">&#160;</font></td>
            <td>
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(Principal
                Executive Officer) </font></div>
            </td>
          </tr>

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{"company-data": {"conformed-name": "eXegenics Inc", "cik": "0000944809", "assigned-sic": "2834", "irs-number": "752402409", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "000-26648", "film-number": "061033574"}, "business-address": {"street1": "1250 PITTSFORD-VICTOR ROAD", "street2": "BUILDING 200, SUITE 280", "city": "PITTSFORD", "state": "NY", "zip": "14534", "phone": "585-218-4368"}, "mail-address": {"street1": "1250 PITTSFORD-VICTOR ROAD", "street2": "BUILDING 200, SUITE 280", "city": "PITTSFORD", "state": "NY", "zip": "14534"}, "former-company": [{"former-conformed-name": "EXEGENICS INC", "date-changed": "20011114"}, {"former-conformed-name": "CYTOCLONAL PHARMACEUTICS INC /DE", "date-changed": "19950503"}]}
UNITED
      STATES
SECURITIES
      AND EXCHANGE COMMISSION
WASHINGTON,
      DC 20549
FORM
      8-K
CURRENT
      REPORT PURSUANT
TO
      SECTION 13 OR 15(
d
)
      OF THE
SECURITIES
      EXCHANGE ACT OF 1934
Date of report (Date of
              earliest
              event reported): August 14, 2006
eXegenics,
                Inc.
(Exact
                Name of Registrant as Specified in Its
                Charter)
Delaware
(State
                or Other Jurisdiction
of
                Incorporation)
000-26648
75-2402409
(Commission
                File Number)
(IRS
                Employer Identification
                No.)
1250
                Pittsford-Victor Road, Building
                200, Suite 280, Pittsford, New York
14534
(Address
                of Principal Executive
                Offices)
(Zip
                Code)
(585)
                218-4368
(
Registrant's
                Telephone Number, Including Area Code)
(Former
                Name or Former Address, if Changed Since
                Last Report)
Check
      the
      appropriate box below if the Form 8-K filing is intended to simultaneously
      satisfy the filing obligation of the registrant under any of the following
      provisions (
see
General
      Instruction A.2. below):
o
Written
                communications pursuant to Rule 425 under the Securities Act (17
                CFR
                230.425)
x
Soliciting material pursuant to Rule
              14a-12
              under the Exchange Act (17 CFR
              240.14a-12)
o
Pre-commencement
                communications pursuant to Rule 14d-2(b) under the Exchange Act (17
                CFR
                240.14d-2(b))
o
Pre-commencement
                communications pursuant to Rule 13e-4(c) under the Exchange Act (17
                CFR
                240.13e-4(c))
Section
      1 - Registrant's Business and Operations
Item
      1.01.
Entry
      into a Material Definitive Agreement
On
      August
      14, 2006, eXegenics, Inc. (the "Company") entered into a Stock Purchase
      Agreement (the "Purchase Agreement") with a group of investors led by Phillip
      Frost, M.D, for the sale of shares of the Company's  common stock. The
      shares of common stock to be issued to the purchasers will constitute, upon
      issuance, 51% of the issued and outstanding shares of common stock of the
      Company, on a fully-diluted basis. The aggregate purchase price to be paid
      for
      the shares is $8,613,000, reflecting the book value of the Company at June
      30,
      2006. The purchase price is subject to adjustment based on the book value of
      the
      Company at the closing date. A closing of the stock purchase is subject to
      certain conditions, as more particularly described in the Purchase Agreement.
      Among other things, a closing of the transaction is subject to the approval
      by
      the stockholders of the Company of (i) an amendment to the certificate of
      incorporation of the Company increasing the number of authorized shares of
      common stock and (ii) the consummation of the transaction.
The
      description above is qualified in its entirety by reference to the Stock
      Purchase Agreement which is filed with this Current Report on Form 8-K as
      Exhibit 10.1 and is incorporated herein by reference.
A
      copy of
      the press release announcing the Company's execution of the Purchase Agreement
      is filed as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated
      herein by reference.
Addtional
      Information
In
        connection with the proposed sale and issuance of shares of eXegenics common
        stock and amendment of eXegenics's certificate of incorporation, eXegenics
        will file a proxy statement with the Commission. SECURITY HOLDERS ARE URGED
        TO
        READ THE  PROXY STATEMENT AND ANY OTHER RELEVANT DOCUMENTS TO BE FILED WITH
        THE COMMISSION, WHEN THEY BECOME AVAILABLE BECAUSE THEY WILL CONTAIN IMPORTANT
        INFORMATION. Security holders may obtain a free copy of the proxy statement
        (when available) and other documents filed by eXegenics at the Commission's
        web
        site at www.sec.gov. The  proxy statement and such other documents may also
        be obtained free of charge from eXegenics Inc. by directing such request
        to
        eXegenics Inc., 1250 Pittsford-Victor Road, Building 200, Suite 280,
        Pittsford, New York 14534, tel: (585) 218-4368.
eXegenics
        and certain of its directors, executive officers and other members of its
        management and employees may be considered to be soliciting proxies from
        eXegenics stockholders in favor of the proposed sale and issuance of shares
        of
        eXegenics common stock and amendment of eXegenics's certificate of
        incorporation. INFORMATION CONCERNING PERSONS WHO MAY BE CONSIDERED PARTICIPANTS
        IN THE SOLICITATION OF EXEGENICS' STOCKHOLDERS UNDER THE RULES OF THE COMMISSION
        IS SET FORTH IN THE PROXY STATEMENT FOR THE 2006 ANNUAL MEETING OF EXEGENICS
        INC. FILED BY EXEGENICS WITH THE COMMISSION ON DECEMBER 13, 2005. Updated
        information concerning these persons will be available in the proxy
        statement.
Section
      7 - Regulation FD
Item
      7.01
Regulation
      FD Disclosure
On
      August
      14, 2006, the Company issued a press release related to its execution of the
      Purchase Agreement. A copy of the press release is filed as Exhibit 99.1 to
      this
      Report on form 8-K and is incorporated herein by reference.
Section
      9 - Financial Statements and Exhibits
Item
      9.01.
Financial
      Statements and Exhibits
(d)
Exhibits:
10.1
Stock
      Purchase Agreement dated as of August 14, 2006
99.1
Press
      Release issued by eXegenics, Inc. dated August 14, 2006.
2
SIGNATURES
Pursuant
      to the requirements of the Securities Exchange Act of 1934, the registrant
      has
      duly caused this report to be signed on its behalf by the undersigned hereunto
      duly authorized.
eXegenics,
              INC.
August
              14, 2006
By:
/s/ John
              A.
              Paganelli
John
              A. Paganelli, Chairman of the Board, Chief Executive
              Officer (Interim) Chief
(Principal
                Executive Officer)
3