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        STATES</strong></font></div>
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        AND EXCHANGE COMMISSION</strong></font></div>
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        DC 20549</strong></font></div>
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        8-K</strong></font></div>
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      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>CURRENT
        REPORT PURSUANT</strong></font></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>TO
        SECTION 13 OR 15(D) OF THE</strong></font></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>SECURITIES
        EXCHANGE ACT OF 1934</strong></font></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Date
        of
        report (Date of earliest event reported): </font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>November
        18, 2005</strong></font></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><br></div>
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                  Inc.</strong></font></div>
              </td>
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              <td valign="top" width="80%" style="BORDER-BOTTOM: medium none">
                <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(Exact
                  Name of Registrant as Specified in Its
                  Charter)</font></div>
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              </td>
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              <td valign="top" width="80%" style="BORDER-BOTTOM: medium none">
                <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(State
                  or Other Jurisdiction</font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">&#160;</font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">of
                  Incorporation)</font></div>
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                  File Number)</font></div>
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                  St. James Avenue, Boston, Massachusetts</strong></font></div>
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                  422-0674</strong></font></div>
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                <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(Former
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      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 27pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Check
        the
        appropriate box below if the Form 8-K filing is intended to simultaneously
        satisfy the filing obligation of the registrant under any of the following
        provisions (</font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><em>see
        </em></font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">General
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      <div style="DISPLAY: block; MARGIN-LEFT: 27pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Wingdings">o</font><font id="TAB2" style="COLOR: black; LETTER-SPACING: 9pt">&#160;</font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Written
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        communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR
        240.13e-4(c))</font></div>
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      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>Item
        3.01 - Notice of Delisting or Failure to Satisfy a Continued Listing Rule
        or
        Standard; Transfer of Listing</strong></font></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><br></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">On
        November 18, 2005 GlycoGenesys, Inc. (the &#8220;Company&#8221;) received a letter from the
        Nasdaq Stock Market indicating that the Company does not comply with the
        minimum
        bid price requirement for continued listing set forth in Nasdaq Marketplace
        Rule
        4310(c)(4) (the &#8220;Bid Price Requirement&#8221;). The Company has a 180 day period
        ending on May 17, 2006 to regain compliance with the Bid Price Requirement.
        If
        the Company&#8217;s closing bid price is at least $1.00 for a period of at least 10
        consecutive trading days, the Company will have regained compliance with
        the Bid
        Price Requirement. If the Company has not regained compliance with the Bid
        Price
        Requirement by May 17, 2006, it will have an additional 180 day period to
        regain
        compliance ending on November 13, 2006 if the Company satisfies initial listing
        requirements (other than the Bid Price Requirement) for the Nasdaq Capital
        Market. </font></div>
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      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">On
        November 18, 2005 the Company also received a letter from the Nasdaq Stock
        Market indicating that based on its Quarterly Report on Form 10-Q for the
        quarter ended September 30, 2005, the Company does not comply with Nasdaq
        Marketplace Rule 4310(c)(2)(B), which requires listed companies to have (i)
        a
        minimum of $2,500,000 in stockholders&#8217; equity, (ii) $35,000,000 or more market
        value of listed securities or (iii) $500,000 of net income from continuing
        operations for the most recently completed fiscal year or two of the three
        most
        recently completed fiscal years. The staff of the Nasdaq Stock Market is
        reviewing the Company&#8217;s eligibility for continued listing on the Nasdaq Capital
        Market and has requested that the Company provide its specific plan to achieve
        and sustain compliance with Nasdaq Capital Market listing requirements.
</font></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">The
        Company will submit a plan to the Nasdaq Stock Market. The staff of the Nasdaq
        Stock Market will review the Company&#8217;s plans and notify the Company if it has
        any questions regarding the Company&#8217;s plan. If the staff of the Nasdaq Stock
        Market believes the Company&#8217;s plan does not adequately address the Company&#8217;s
        achieving and sustaining compliance with listing requirements, it will provide
        notification that the Company&#8217;s securities will be delisted. In such event, the
        Company may appeal the staff&#8217;s decision to a Nasdaq Listing Qualifications
        Panel. Such an appeal would stay the delisting of the Company&#8217;s common stock
        pending the decision of a Nasdaq Listing Qualifications Panel, which generally
        hears appeals within 45 days of request. The Company estimates that if a
        hearing
        was determined to be necessary, it would be held in January 2006. </font></div>
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      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
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          <div style="WIDTH: 100%; TEXT-ALIGN: center">&#160;</div>
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      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>SIGNATURES</strong></font></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><br></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Pursuant
        to the requirements of the Securities Exchange Act of 1934, the Registrant
        has
        duly caused this report to be signed on its behalf by the undersigned hereunto
        duly authorized.</font></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><br></div>
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        <table align="center" bgcolor="#ffffff" border="0" cellpadding="0" cellspacing="0" width="100%">

            <tr valign="top" bgcolor="#ffffff">
              <td width="50%"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">&#160;</font></td>
              <td width="1%"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">&#160;</font></td>
              <td width="49%"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">&#160;</font></td>
            </tr>
            <tr valign="top" bgcolor="#ffffff">
              <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">&#160;</font></td>
              <td colspan="2"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>GLYCOGENESYS,
                INC.</strong></font></td>
            </tr>
            <tr valign="top" bgcolor="#ffffff">
              <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">&#160;<br>&#160;</font></td>
              <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">&#160;<br>&#160;</font></td>
              <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">&#160;<br>&#160;</font></td>
            </tr>
            <tr valign="top" bgcolor="#ffffff">
              <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Dated:&#160;
                November 23, 2005</font></td>
              <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">By:&#160;&#160;</font></td>
              <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">/s/&#160;William
                O. Fabbri</font></td>
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                <div><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">William
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                <div><font size="2">General Counsel</font></div>
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{"company-data": {"conformed-name": "GLYCOGENESYS  INC", "cik": "0000946661", "assigned-sic": "2836", "irs-number": "330231238", "state-of-incorporation": "NV", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "000-26476", "film-number": "051225125"}, "business-address": {"street1": "31 ST. JAMES AVENUE", "street2": "8TH FLOOR", "city": "BOSTON", "state": "MA", "zip": "02116", "phone": "6174220674"}, "mail-address": {"street1": "31 ST JAMES AVE", "street2": "8TH FL", "city": "BOSTON", "state": "MA", "zip": "02116"}, "former-company": [{"former-conformed-name": "GLYCOGENESY  INC", "date-changed": "20011107"}, {"former-conformed-name": "SAFESCIENCE INC", "date-changed": "19980401"}, {"former-conformed-name": "IGG INTERNATIONAL INC", "date-changed": "19950721"}]}
UNITED
        STATES
SECURITIES
        AND EXCHANGE COMMISSION
WASHINGTON,
        DC 20549
FORM
        8-K
CURRENT
        REPORT PURSUANT
TO
        SECTION 13 OR 15(D) OF THE
SECURITIES
        EXCHANGE ACT OF 1934
Date
        of
        report (Date of earliest event reported):
November
        18, 2005
GlycoGenesys,
                  Inc.
(Exact
                  Name of Registrant as Specified in Its
                  Charter)
Nevada
(State
                  or Other Jurisdiction
of
                  Incorporation)
0-26476
33-0231238
(Commission
                  File Number)
(IRS
                  Employer Identification No.)
31
                  St. James Avenue, Boston, Massachusetts
02116
(Address
                  of Principal Executive Offices)
(Zip
                  Code)
(617)
                  422-0674
(
Registrant's
                  Telephone Number, Including Area
                  Code)
Not
                  Applicable
(Former
                  Name or Former Address, if Changed Since Last
                  Report)
Check
        the
        appropriate box below if the Form 8-K filing is intended to simultaneously
        satisfy the filing obligation of the registrant under any of the following
        provisions (
see
General
        Instruction A.2. below):
o
Written
        communications pursuant to Rule 425 under the Securities Act (17 CFR
        230.425)
o
Soliciting
        material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
        240.14a-12)
o
Pre-commencement
        communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR
        240.14d-2(b))
o
Pre-commencement
        communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR
        240.13e-4(c))
Item
        3.01 - Notice of Delisting or Failure to Satisfy a Continued Listing Rule
        or
        Standard; Transfer of Listing
On
        November 18, 2005 GlycoGenesys, Inc. (the "Company") received a letter from the
        Nasdaq Stock Market indicating that the Company does not comply with the
        minimum
        bid price requirement for continued listing set forth in Nasdaq Marketplace
        Rule
        4310(c)(4) (the "Bid Price Requirement"). The Company has a 180 day period
        ending on May 17, 2006 to regain compliance with the Bid Price Requirement.
        If
        the Company's closing bid price is at least $1.00 for a period of at least 10
        consecutive trading days, the Company will have regained compliance with
        the Bid
        Price Requirement. If the Company has not regained compliance with the Bid
        Price
        Requirement by May 17, 2006, it will have an additional 180 day period to
        regain
        compliance ending on November 13, 2006 if the Company satisfies initial listing
        requirements (other than the Bid Price Requirement) for the Nasdaq Capital
        Market.
On
        November 18, 2005 the Company also received a letter from the Nasdaq Stock
        Market indicating that based on its Quarterly Report on Form 10-Q for the
        quarter ended September 30, 2005, the Company does not comply with Nasdaq
        Marketplace Rule 4310(c)(2)(B), which requires listed companies to have (i)
        a
        minimum of $2,500,000 in stockholders' equity, (ii) $35,000,000 or more market
        value of listed securities or (iii) $500,000 of net income from continuing
        operations for the most recently completed fiscal year or two of the three
        most
        recently completed fiscal years. The staff of the Nasdaq Stock Market is
        reviewing the Company's eligibility for continued listing on the Nasdaq Capital
        Market and has requested that the Company provide its specific plan to achieve
        and sustain compliance with Nasdaq Capital Market listing requirements.
The
        Company will submit a plan to the Nasdaq Stock Market. The staff of the Nasdaq
        Stock Market will review the Company's plans and notify the Company if it has
        any questions regarding the Company's plan. If the staff of the Nasdaq Stock
        Market believes the Company's plan does not adequately address the Company's
        achieving and sustaining compliance with listing requirements, it will provide
        notification that the Company's securities will be delisted. In such event, the
        Company may appeal the staff's decision to a Nasdaq Listing Qualifications
        Panel. Such an appeal would stay the delisting of the Company's common stock
        pending the decision of a Nasdaq Listing Qualifications Panel, which generally
        hears appeals within 45 days of request. The Company estimates that if a
        hearing
        was determined to be necessary, it would be held in January 2006.
SIGNATURES
Pursuant
        to the requirements of the Securities Exchange Act of 1934, the Registrant
        has
        duly caused this report to be signed on its behalf by the undersigned hereunto
        duly authorized.
GLYCOGENESYS,
                INC.
Dated: 
                November 23, 2005
By:
/s/ William
                O. Fabbri
William
                  O. Fabbri
General Counsel