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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 18.5pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>UNITED
      STATES </strong></font></div>
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      AND EXCHANGE COMMISSION </strong></font></div>
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      D.C. 20549 </strong></font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
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      8-K</strong></font></div>
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      REPORT </strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 18.5pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>Pursuant
      to Section&#160;13 or 15(d) of the </strong></font></div>
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      Exchange Act of 1934 </strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
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      of
      Report (Date of Earliest Event Reported): </font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><u>May
      22, 2006</u></font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 12.15pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><u>433
      Hackensack Avenue, Hackensack, NJ 07601</u></font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 12.15pt" align="center"><br></div>
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      Telephone Number, including Area Code: </font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><u>(201)
      968-0980</u></font></div>
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      applicable </u></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 12.15pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(Former
      Name or Former Address, if Changed Since Last Report) </font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 12.15pt" align="center"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 12.15pt" align="center"><br></div>
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      the
      appropriate box below if the Form 8-K filing is intended to simultaneously
      satisfy the filing obligation of registrant under any of the following
      provisions: </font></div>
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      communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
      </font></div>
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      material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
      </font></div>
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      communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR
      240-14d-2(b)) </font></div>
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      communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR
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    <div>&#160;</div>
    <div id="PGBRK" style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt">
      <div id="FTR">
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        <div style="WIDTH: 100%; TEXT-ALIGN: center">
          <hr style="COLOR: black" noshade size="2">
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      </div>
      <div id="HDR">
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    <div>&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>Special
      Note Regarding Forward-Looking Statements</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">This
      Current Report on Form 8-K includes forward-looking statements within the
      meaning of Section 27A of the Securities Act of 1933 and Section 21E of the
      Securities Exchange Act of 1934, each as amended, including statements regarding
      our expectations with respect to the progress of and level of expenses for
      our
      clinical trial programs. You can also identify forward-looking statements by
      the
      following words: may, will, should, expect, intend, plan, anticipate, believe,
      estimate, predict, potential, continue or the negative of these terms or other
      comparable terminology. We caution you that forward-looking statements are
      inherently uncertain and are simply point-in-time estimates based on a
      combination of facts and factors currently known by us about which we cannot
      be
      certain or even relatively confident. Actual results or events will surely
      differ and may differ materially from our forward-looking statements as a result
      of many factors, some of which we may not be able to predict or may not be
      within our control. Such factors may also materially adversely affect our
      ability to achieve our objectives and to successfully develop and commercialize
      our product candidates, including our ability to:</font></div>
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    <div>
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            <td align="right" valign="top" width="9%">
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            </td>
            <td align="left" valign="top" width="71%">
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                the safety and efficacy of product candidates at each stage of
                development; </font></div>
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    <div>
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          <tr>
            <td align="right" valign="top" width="9%">
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              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">develop
                and execute Phase II and III clinical programs for bicifadine, our
                novel
                analgesic, revised as necessary to take into account the drug&#8217;s recent
                failure to achieve statistically significant effects relative to
                placebo;</font></div>
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          <tr>
            <td align="right" valign="top" width="9%">
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            </td>
            <td align="left" valign="top" width="71%">
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                our development schedule for our product candidates, including with
                respect to clinical trial initiation, enrollment and
                completion;</font></div>
            </td>
          </tr>

      </table>
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    <div>
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          <tr>
            <td align="right" valign="top" width="9%">
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="right"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Symbol, serif">&#183;</font></div>
            </td>
            <td align="left" valign="top" width="71%">
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">meet
                applicable regulatory standards and receive required regulatory approvals
                on our anticipated time schedule or at
                all;</font></div>
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          </tr>

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          <tr>
            <td align="right" valign="top" width="9%">
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="right"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Symbol, serif">&#183;</font></div>
            </td>
            <td align="left" valign="top" width="71%">
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">meet
                or require our partners to meet obligations and achieve milestones
                under
                our license and other agreements; </font></div>
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          <tr>
            <td align="right" valign="top" width="9%">
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            </td>
            <td align="left" valign="top" width="71%">
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">successfully
                execute the development plan under and otherwise achieve the results
                contemplated by the 2005 amendment to our license agreement with
                Merck;</font></div>
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          <tr>
            <td align="right" valign="top" width="9%">
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            </td>
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                and maintain collaborations as required with pharmaceutical
                partners;</font></div>
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                compete
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: -18pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><br></div>
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      should refer to the &#8220;Part II&#8212;Other Information&#8221; section of our report on Form
      10-Q for the quarter ended March 31, 2006 under the subheading &#8220;Item IA. Risk
      Factors&#8221; for a detailed discussion of some of the factors that may cause our
      actual results to differ materially from our forward-looking statements. We
      qualify all our forward-looking statements by these cautionary statements.
      There
      may also be other material factors that may materially affect our
      forward-looking statements and our future results. As a result of the foregoing,
      readers should not place undue reliance on our forward-looking statements.
      We do
      not undertake any obligation and do not intend to update any forward-looking
      statement.</font></div>
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      REGULATION FD DISCLOSURE</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
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      24, 2006, DOV Pharmaceutical, Inc. announced high-level results developed from
      the first Phase III placebo-controlled clinical trial - study 020 - of our
      novel
      analgesic bicifadine in patients with chronic low back pain (CLBP). In
      connection with this announcement, we indicated that we would conduct a more
      detailed assessment of the trial data in order to better understand the factors
      which were responsible for the findings announced on April 24. The press release
      issued by us today, May 22, 2006, a copy of which is attached as Exhibit 99.1
      hereto, includes certain information developed by us as we conducted this
      detailed assessment. As noted in our press release, we will host a conference
      call on May 22, 2006. On this conference call, a member or members of our senior
      management team will discuss this assessment and the information developed
      from
      the assessment. Visual aids in the form of the slides attached as Exhibit 99.2
      hereto will be used during this conference call. The slides attached as Exhibit
      99.2 have also been posted on our web site </font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><u>www.dovpharm.com</u></font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">.</font></div>
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      information included or incorporated by reference in this Item 7.01 of this
      Current Report on Form 8-K is furnished pursuant to Item 7.01 and shall not
      be
      deemed to be &#8220;filed&#8221; for the purposes of Section 18 of the Securities Exchange
      Act of 1934, as amended, or otherwise subject to the liabilities of that
      Section, nor shall it be deemed incorporated by reference in any filing(s)
      of
      the registrant under the Securities Act of 1933, as amended.&#160; Furthermore,
      the furnishing of the information included or incorporated by reference in
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      information is required by Regulation FD.</font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
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      &#160;Exhibits. The following exhibits are filed with this Current Report on
      Form 8-K.</font></div>
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                No.</strong></font></div>
            </td>
            <td align="left" valign="middle" width="5%">
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
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              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
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              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
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                release, dated May 22, 2006, of DOV Pharmaceutical, Inc.
                (*)</font></div>
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            <td align="left" valign="top" width="15%">
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">99.2</font></div>
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              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
            </td>
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              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Slide
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">(*)
      The
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      furnished pursuant to Item 7.01 and shall not be deemed to be &#8220;filed&#8221; for the
      purposes of Section 18 of the Securities Exchange Act of 1934, as amended,
      or
      otherwise subject to the liabilities of that Section, nor shall it be deemed
      incorporated by reference in any filing(s) of the registrant under the
      Securities Act of 1933, as amended.&#160; Furthermore, the furnishing of the
      information included in these exhibits to this Report is not intended to
      constitute a determination by the registrant that the information is material
      or
      that the dissemination of the information is required by Regulation
      FD.</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 27pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Pursuant
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      duly
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
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            <td align="left" valign="bottom" width="2%">
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">&#160;
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                </font></div>
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              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">&#160;
                </font></div>
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            <td align="left" valign="bottom" width="2%">
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">&#160;
                </font></div>
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            <td align="left" valign="bottom" width="2%">
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                </font></div>
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            <td align="left" valign="bottom" width="2%">
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">&#160;
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            <td align="left" valign="middle" width="4%">
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">&#160;
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            <td align="left" valign="middle" width="10%">&#160;</td>
            <td align="left" valign="middle" width="2%">&#160;</td>
            <td align="left" valign="middle" width="2%">&#160;</td>
            <td align="left" colspan="2" valign="middle" width="52%">&#160;</td>
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            <td align="left" valign="top" width="4%">
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                </font></div>
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            <td align="left" valign="bottom" width="2%">
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">&#160;
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                22, 2006</font></div>
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              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">&#160;
                </font></div>
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              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">By:
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            <td align="left" valign="bottom" width="2%">
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">&#160;
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                Leslie Hudson</font></div>
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            </td>
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            <td align="left" valign="bottom" width="2%">&#160;</td>
            <td align="left" valign="top" width="28%">&#160;</td>
            <td align="left" valign="bottom" width="10%">&#160;</td>
            <td align="left" valign="top" width="2%">&#160;</td>
            <td align="left" valign="bottom" width="2%">&#160;</td>
            <td align="left" colspan="2" valign="top" width="52%">&#160;

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              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">President
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                No.</strong></font></div>
            </td>
            <td align="left" valign="middle" width="3%">
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
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            <td align="left" valign="top" width="65%" style="border-bottom: black thin solid;">
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
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            </td>
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            <td align="left" valign="top" width="12%">
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
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            <td align="left" valign="middle" width="3%">
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
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              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Press
                release, dated May 22, 2006, of DOV Pharmaceutical, Inc.
                (*)</font></div>
            </td>
          </tr>
          <tr>
            <td align="left" valign="top" width="12%">
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              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">99.2</font></div>
            </td>
            <td align="left" valign="middle" width="3%">
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
            </td>
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              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Slide
                presentation of DOV Pharmaceutical, Inc.
                (*)</font></div>
            </td>
          </tr>

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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
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      The
      information included in these exhibits to this Current Report on Form 8-K is
      furnished pursuant to Item 7.01 and shall not be deemed to be &#8220;filed&#8221; for the
      purposes of Section 18 of the Securities Exchange Act of 1934, as amended,
      or
      otherwise subject to the liabilities of that Section, nor shall it be deemed
      incorporated by reference in any filing(s) of the registrant under the
      Securities Act of 1933, as amended.&#160; Furthermore, the furnishing of the
      information included in these exhibits to this Report is not intended to
      constitute a determination by the registrant that the information is material
      or
      that the dissemination of the information is required by Regulation
      FD.</font></div>
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{"company-data": {"conformed-name": "DOV PHARMACEUTICAL INC", "cik": "0001066833", "assigned-sic": "2834", "irs-number": "223374365", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "000-49730", "film-number": "06859353"}, "business-address": {"street1": "433 HACKENSACK AVENUE", "city": "HACKENSACK", "state": "NJ", "zip": "07601", "phone": "2019680980"}, "mail-address": {"street1": "433 HACKENSACK AVENUE", "city": "HACKENSACK", "state": "NJ", "zip": "07601"}}
UNITED
      STATES
SECURITIES
      AND EXCHANGE COMMISSION
WASHINGTON,
      D.C. 20549
__________
FORM
      8-K
CURRENT
      REPORT
Pursuant
      to Section 13 or 15(d) of the
Securities
      Exchange Act of 1934
Date
      of
      Report (Date of Earliest Event Reported):
May
      22, 2006
DOV
PHARMACEUTICAL,
      INC.
(Exact
      Name of Registrant as Specified in Charter)
Delaware
000-49730
22-3374365
(State
                or Other Jurisdiction of Incorporation)
(Commission
                File No.)
(IRS
                Employer Identification No.)
433
      Hackensack Avenue, Hackensack, NJ 07601
(Address
      of Principal Executive Offices) (Zip Code)
Registrant's
      Telephone Number, including Area Code:
(201)
      968-0980
Not
      applicable
(Former
      Name or Former Address, if Changed Since Last Report)
Check
      the
      appropriate box below if the Form 8-K filing is intended to simultaneously
      satisfy the filing obligation of registrant under any of the following
      provisions:
࿠
Written
      communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
࿠
Soliciting
      material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
࿠
Pre-commencement
      communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR
      240-14d-2(b))
࿠
Pre-commencement
      communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR
      240-13e-4(c))
Special
      Note Regarding Forward-Looking Statements
This
      Current Report on Form 8-K includes forward-looking statements within the
      meaning of Section 27A of the Securities Act of 1933 and Section 21E of the
      Securities Exchange Act of 1934, each as amended, including statements regarding
      our expectations with respect to the progress of and level of expenses for
      our
      clinical trial programs. You can also identify forward-looking statements by
      the
      following words: may, will, should, expect, intend, plan, anticipate, believe,
      estimate, predict, potential, continue or the negative of these terms or other
      comparable terminology. We caution you that forward-looking statements are
      inherently uncertain and are simply point-in-time estimates based on a
      combination of facts and factors currently known by us about which we cannot
      be
      certain or even relatively confident. Actual results or events will surely
      differ and may differ materially from our forward-looking statements as a result
      of many factors, some of which we may not be able to predict or may not be
      within our control. Such factors may also materially adversely affect our
      ability to achieve our objectives and to successfully develop and commercialize
      our product candidates, including our ability to:
·
demonstrate
                the safety and efficacy of product candidates at each stage of
                development;
·
develop
                and execute Phase II and III clinical programs for bicifadine, our
                novel
                analgesic, revised as necessary to take into account the drug's recent
                failure to achieve statistically significant effects relative to
                placebo;
·
meet
                our development schedule for our product candidates, including with
                respect to clinical trial initiation, enrollment and
                completion;
·
meet
                applicable regulatory standards and receive required regulatory approvals
                on our anticipated time schedule or at
                all;
·
meet
                or require our partners to meet obligations and achieve milestones
                under
                our license and other agreements;
·
successfully
                execute the development plan under and otherwise achieve the results
                contemplated by the 2005 amendment to our license agreement with
                Merck;
·
obtain
                and maintain collaborations as required with pharmaceutical
                partners;
·
obtain
                substantial additional funds;
·
obtain
                and maintain all necessary patents, licenses and other intellectual
                property rights; and
·
produce
                drug candidates in commercial quantities at reasonable costs and
                compete
                successfully against other products and
                companies.
You
      should refer to the "Part II—Other Information" section of our report on Form
      10-Q for the quarter ended March 31, 2006 under the subheading "Item IA. Risk
      Factors" for a detailed discussion of some of the factors that may cause our
      actual results to differ materially from our forward-looking statements. We
      qualify all our forward-looking statements by these cautionary statements.
      There
      may also be other material factors that may materially affect our
      forward-looking statements and our future results. As a result of the foregoing,
      readers should not place undue reliance on our forward-looking statements.
      We do
      not undertake any obligation and do not intend to update any forward-looking
      statement.
ITEM 7.01.
      REGULATION FD DISCLOSURE
On
      April
      24, 2006, DOV Pharmaceutical, Inc. announced high-level results developed from
      the first Phase III placebo-controlled clinical trial - study 020 - of our
      novel
      analgesic bicifadine in patients with chronic low back pain (CLBP). In
      connection with this announcement, we indicated that we would conduct a more
      detailed assessment of the trial data in order to better understand the factors
      which were responsible for the findings announced on April 24. The press release
      issued by us today, May 22, 2006, a copy of which is attached as Exhibit 99.1
      hereto, includes certain information developed by us as we conducted this
      detailed assessment. As noted in our press release, we will host a conference
      call on May 22, 2006. On this conference call, a member or members of our senior
      management team will discuss this assessment and the information developed
      from
      the assessment. Visual aids in the form of the slides attached as Exhibit 99.2
      hereto will be used during this conference call. The slides attached as Exhibit
      99.2 have also been posted on our web site
www.dovpharm.com
.
The
      information included or incorporated by reference in this Item 7.01 of this
      Current Report on Form 8-K is furnished pursuant to Item 7.01 and shall not
      be
      deemed to be "filed" for the purposes of Section 18 of the Securities Exchange
      Act of 1934, as amended, or otherwise subject to the liabilities of that
      Section, nor shall it be deemed incorporated by reference in any filing(s)
      of
      the registrant under the Securities Act of 1933, as amended.  Furthermore,
      the furnishing of the information included or incorporated by reference in
      this
      Item 7.01 of this Report is not intended to constitute a determination by the
      registrant that the information is material or that the dissemination of the
      information is required by Regulation FD.
ITEM
      9.01. EXHIBITS.
(d)
       Exhibits. The following exhibits are filed with this Current Report on
      Form 8-K.
Exhibit
                No.
Title
99.1
Press
                release, dated May 22, 2006, of DOV Pharmaceutical, Inc.
                (*)
99.2
Slide
                presentation of DOV Pharmaceutical, Inc.
                (*)
(*)
      The
      information included in these exhibits to this Current Report on Form 8-K is
      furnished pursuant to Item 7.01 and shall not be deemed to be "filed" for the
      purposes of Section 18 of the Securities Exchange Act of 1934, as amended,
      or
      otherwise subject to the liabilities of that Section, nor shall it be deemed
      incorporated by reference in any filing(s) of the registrant under the
      Securities Act of 1933, as amended.  Furthermore, the furnishing of the
      information included in these exhibits to this Report is not intended to
      constitute a determination by the registrant that the information is material
      or
      that the dissemination of the information is required by Regulation
      FD.
SIGNATURES
Pursuant
      to the requirements of the Securities Exchange Act of 1934, registrant has
      duly
      caused this report to be signed on its behalf by the undersigned thereunto
      duly
      authorized.
DOV
                Pharmaceutical, Inc.
Date:
May
                22, 2006
By:
/s/
                Leslie Hudson
Leslie
                Hudson
President
                and CEO
EXHIBIT
      INDEX
Exhibit
                No.
Title
99.1
Press
                release, dated May 22, 2006, of DOV Pharmaceutical, Inc.
                (*)
99.2
Slide
                presentation of DOV Pharmaceutical, Inc.
                (*)
(*)
      The
      information included in these exhibits to this Current Report on Form 8-K is
      furnished pursuant to Item 7.01 and shall not be deemed to be "filed" for the
      purposes of Section 18 of the Securities Exchange Act of 1934, as amended,
      or
      otherwise subject to the liabilities of that Section, nor shall it be deemed
      incorporated by reference in any filing(s) of the registrant under the
      Securities Act of 1933, as amended.  Furthermore, the furnishing of the
      information included in these exhibits to this Report is not intended to
      constitute a determination by the registrant that the information is material
      or
      that the dissemination of the information is required by Regulation
      FD.