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      1934</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><br></div>
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      LABORATORIES, INC.</u></strong></font></div>
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      File No. 1-10352</font></div>
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                No.)</font></div>
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                Eisenhower Parkway</font></div>
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                of principal</font></div>
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      telephone number, including area code: (973) 994-3999</font></div>
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      the
      appropriate box below if the Form 8-K filing is intended to simultaneously
      satisfy the filing obligation of the registrant under any of the following
      provisions (see General Instruction A.2. below):</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><br></div>
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      Written communications
      pursuant to Rule 425 under the Securities Act (17 CFR 230.425)</font></div>
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      Soliciting material pursuant to Rule
      14a-12 under the Exchange Act (17 CFR 240.14a-12)</font></div>
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      Pre-commencement communications pursuant
      to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))</font></div>
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      Pre-commencement communications pursuant
      to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))</font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>Item
      2.02</strong></font><font id="TAB2" style="COLOR: black; LETTER-SPACING: 27pt">&#160;</font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>Results
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">On
      March
      7, 2006, Columbia Laboratories, Inc. (the &#8220;Company&#8221;), issued a press release
      entitled, &#8220;Columbia Laboratories Reports Fourth Quarter and Year-end 2005
      Financial Results.&#8221; A copy of the press release issued by the Company is filed
      herewith as Exhibit 99.1.</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">The
      information contained in this Current Report on Form 8-K, including
      Exhibit&#160;99.1, is being furnished and shall not be deemed to be &#8220;filed&#8221; for
      purposes of Section&#160;18 of the Securities Exchange Act of 1934, as amended,
      or otherwise subject to the liabilities of Section&#160;18. Furthermore, the
      information contained in this Current Report shall not be deemed to be
      incorporated by reference into any registration statement or other document
      filed pursuant to the Securities Act of 1933, as amended. </font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>Item
      5.02</strong></font><font id="TAB2" style="COLOR: black; LETTER-SPACING: 0.8pt">&#160;</font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>Departure
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      Principal Officers.</strong></font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">On
      March
      6, 2006, the Company's Board of Directors elected Robert S. Mills as chief
      executive officer of the Company. Mr. Mills also continues to serve as president
      of the Company.</font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Mr.
      Mills, age 53, joined the Company in May 2001, as senior vice president,
      operations, and was named chief operating officer in September 2003 and
      president and chief operating officer in January 2006. Previously, Mr. Mills
      served as senior vice president, manufacturing operations, at Watson
      Pharmaceuticals and general manager of Schein Pharmaceuticals, now Watson
      Pharma, Inc. He also served as vice president, operations, at Alpharma, Inc.
      and
      held various positions with Aventis, SA. Mr. Mills holds a BS degree from Grove
      City College.</font></div>
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      Mills
      entered into an employment agreement with the Company in February, 2005. The
      material terms of the employment agreement are described in the Company's Proxy
      Statement for the 2005 Annual Meeting of Stockholders, which description is
      incorporated herein by reference.</font><br></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>Item
      8.01</strong></font><font id="TAB2" style="COLOR: black; LETTER-SPACING: 27pt">&#160;</font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>Other
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">On
      March
      7, 2006, the Company issued a press release entitled &#8220;</font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Robert
      S.
      Mills Elected Chief Executive Officer of Columbia Laboratories</font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">.&#8221;
A
      copy
      of the Company&#8217;s press release is attached hereto as Exhibit 99.2 and is
      incorporated herein by reference.</font></div>
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      Exhibits.&#160; </font></div>
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                </td>
                <td align="left" style="width: 27pt;"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">99.1</font></td>
                <td align="left">
                  <div align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Press
                    Release dated March 7, 2006, entitled &#8220;Columbia Laboratories Reports
                    Fourth Quarter and Year-end 2005 Financial
                    Results.&#8221;</font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
    <div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.3; MARGIN-RIGHT: 0pt" align="left">
        <div>
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                <td style="width: 27pt;">
                </td>
                <td align="left" style="width: 27pt;"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">99.2</font></td>
                <td align="left">
                  <div align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Press
                    Release dated March 7, 2006, entitled &#8220;Robert S. Mills Elected Chief
                    Executive Officer of Columbia
                    Laboratories.&#8221;</font></div>
                </td>
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      to the requirements of the Securities Exchange Act of 1934, the registrant
      has
      duly caused this report to be signed on its behalf by the undersigned hereunto
      duly authorized.</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Date:
      March 7, 2006</font></div>
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            <tr valign="top" bgcolor="#ffffff">
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              <td width="1%"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">&#160;</font></td>
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              <td colspan="2"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: "><strong>COLUMBIA
                LABORATORIES, INC.</strong></font></td>
            </tr>
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              <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">&#160;<br>&#160;</font></td>
              <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">&#160;<br>&#160;</font></td>
              <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">&#160;<br>&#160;</font></td>
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              <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">By:&#160;&#160;</font></td>
              <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">/S/&#160;David
                L.
                Weinberg</font></td>
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                <hr style="COLOR: black" align="left" noshade size="2" width="80%"><font size="2">David
                L. Weinberg</font></td>
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              <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">Vice
                President and Chief Financial
                Officer</font></td>
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      Index</strong></font></div>
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                No.</strong></font></div>
            </td>
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                Release dated March 7, 2006, entitled &#8220;Columbia Laboratories Reports
                Fourth Quarter and Year-end 2005 Financial Results.&#8221;</font></div>
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                Release dated March 7, 2006, entitled &#8220;Robert S. Mills Elected Chief
                Executive Officer of Columbia
                Laboratories.&#8221;</font></div>
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{"company-data": {"conformed-name": "COLUMBIA LABORATORIES INC", "cik": "0000821995", "assigned-sic": "2834", "irs-number": "592758596", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "001-10352", "film-number": "06669535"}, "business-address": {"street1": "354 EISENHOWER PARKWAY", "city": "LIVINGSTON", "state": "NJ", "zip": "07039", "phone": "9739943999"}, "mail-address": {"street1": "354 EISENHOWER PARKWAY", "city": "LIVINGSTON", "state": "NJ", "zip": "07039"}}
SECURITIES
      AND EXCHANGE COMMISSION
WASHINGTON,
      D.C.  20549
FORM
      8-K
CURRENT
      REPORT
Pursuant
      to Section 13 OR 15(d) of the Securities Exchange Act of
      1934
DATE
      OF
      REPORT - March 6, 2006
(Date
      of
      Earliest Event Reported)
COLUMBIA
      LABORATORIES, INC.
(Exact
      name of registrant as specified in its charter)
Commission
      File No. 1-10352
Delaware
59-2758596
(State
                of Incorporation)
(I.R.S.
                Employer
Identification
                No.)
354
                Eisenhower Parkway
Livingston,
                New Jersey
07039
(Address
                of principal
executive
                offices)
Zip
                Code
Registrant's
      telephone number, including area code: (973) 994-3999
Check
      the
      appropriate box below if the Form 8-K filing is intended to simultaneously
      satisfy the filing obligation of the registrant under any of the following
      provisions (see General Instruction A.2. below):
o
Written communications
      pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
o
Soliciting material pursuant to Rule
      14a-12 under the Exchange Act (17 CFR 240.14a-12)
o
Pre-commencement communications pursuant
      to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
o
Pre-commencement communications pursuant
      to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Item
      2.02
Results
      of Operations and Financial Condition
On
      March
      7, 2006, Columbia Laboratories, Inc. (the "Company"), issued a press release
      entitled, "Columbia Laboratories Reports Fourth Quarter and Year-end 2005
      Financial Results." A copy of the press release issued by the Company is filed
      herewith as Exhibit 99.1.
The
      information contained in this Current Report on Form 8-K, including
      Exhibit 99.1, is being furnished and shall not be deemed to be "filed" for
      purposes of Section 18 of the Securities Exchange Act of 1934, as amended,
      or otherwise subject to the liabilities of Section 18. Furthermore, the
      information contained in this Current Report shall not be deemed to be
      incorporated by reference into any registration statement or other document
      filed pursuant to the Securities Act of 1933, as amended.
Item
      5.02
Departure
      of Directors or Principal Officers; Election of Directors; Appointment of
      Principal Officers.
On
      March
      6, 2006, the Company's Board of Directors elected Robert S. Mills as chief
      executive officer of the Company. Mr. Mills also continues to serve as president
      of the Company.
Mr.
      Mills, age 53, joined the Company in May 2001, as senior vice president,
      operations, and was named chief operating officer in September 2003 and
      president and chief operating officer in January 2006. Previously, Mr. Mills
      served as senior vice president, manufacturing operations, at Watson
      Pharmaceuticals and general manager of Schein Pharmaceuticals, now Watson
      Pharma, Inc. He also served as vice president, operations, at Alpharma, Inc.
      and
      held various positions with Aventis, SA. Mr. Mills holds a BS degree from Grove
      City College.
Mr.
      Mills
      entered into an employment agreement with the Company in February, 2005. The
      material terms of the employment agreement are described in the Company's Proxy
      Statement for the 2005 Annual Meeting of Stockholders, which description is
      incorporated herein by reference.
Item
      8.01
Other
      Events.
On
      March
      7, 2006, the Company issued a press release entitled "
Robert
      S.
      Mills Elected Chief Executive Officer of Columbia Laboratories
."
A
      copy
      of the Company's press release is attached hereto as Exhibit 99.2 and is
      incorporated herein by reference.
Item
      9.01
Financial
      Statements and Exhibits
(c)       
      Exhibits.
99.1
Press
                    Release dated March 7, 2006, entitled "Columbia Laboratories Reports
                    Fourth Quarter and Year-end 2005 Financial
                    Results."
99.2
Press
                    Release dated March 7, 2006, entitled "Robert S. Mills Elected Chief
                    Executive Officer of Columbia
                    Laboratories."
SIGNATURE
Pursuant
      to the requirements of the Securities Exchange Act of 1934, the registrant
      has
      duly caused this report to be signed on its behalf by the undersigned hereunto
      duly authorized.
Date:
      March 7, 2006
COLUMBIA
                LABORATORIES, INC.
By:
/S/ David
                L.
                Weinberg
David
                L. Weinberg
Vice
                President and Chief Financial
                Officer
Exhibit
      Index
Exhibit
                No.
Description
99.1
Press
                Release dated March 7, 2006, entitled "Columbia Laboratories Reports
                Fourth Quarter and Year-end 2005 Financial Results."
99.2
Press
                Release dated March 7, 2006, entitled "Robert S. Mills Elected Chief
                Executive Officer of Columbia
                Laboratories."