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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">UNITED
      STATES</font></div>
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      AND EXCHANGE COMMISSION</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">WASHINGTON,
      D.C. 20549</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
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      8-K</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">CURRENT
      REPORT</font></div>
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      TO SECTION 13 OR 15(d) OF</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">THE
      SECURITIES EXCHANGE ACT OF 1934</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Date
      of
      report (date of earliest event reported): June 8, 2006</font></div>
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      BIOTECHNOLOGY, INC.</strong></font></div>
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      name of registrant as specified in its charter)</font></div>
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      943-8040</strong></font></div>
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      the
      appropriate box below if the Form 8-K filing is intended to simultaneously
      satisfy the filing obligation of the registrant under any of the following
      provisions:</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
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      Soliciting material pursuant to Rule 14a-12 under the
      Exchange Act (17 CFR 240.14a-12)</font></div>
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      Pre-commencement communications pursuant to Rule
      14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))</font></div>
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      13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))</font></div>
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      5.02</strong></font><font id="TAB2" style="COLOR: black; LETTER-SPACING: 27pt">&#160;</font><a name="id_7"/><a name="id_8"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>Departure
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      Since April 2002, Mr. Richman, age 45, has served as the Executive Vice
      President and Chief Operating Officer of MacroGenics, Inc., a privately held
      biotechnology company based in Rockville, Maryland that is engaged in the
      development of immune-based products, including monoclonal antibodies to treat
      patients with cancer, autoimmune disorders, allergy, or infectious diseases
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      March 2002, Mr. Richman served as Senior Vice President, Corporate Development
      and Administration, for MedImmune, Inc. (NASDAQ: MEDI), a Gaithersburg, Maryland
      based company that is engaged in the development of immunotherapeutics focusing
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      to
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      duly caused this report to be signed on its behalf by the undersigned hereunto
      duly authorized.</font></div>
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            <td width="1%"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">&#160;</font></td>
            <td width="49%"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">&#160;</font></td>
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            <td colspan="2"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">COUGAR
              BIOTECHNOLOGY, INC.</font></td>
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            <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">Date:
              June 13, 2006&#160;</font></td>
            <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">By:&#160;&#160;</font></td>
            <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">/s/&#160;Alan
              H.
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            <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">Chief
              Executive Officer and President</font></td>
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Unassociated Document
UNITED
      STATES
SECURITIES
      AND EXCHANGE COMMISSION
WASHINGTON,
      D.C. 20549
FORM
      8-K
CURRENT
      REPORT
PURSUANT
      TO SECTION 13 OR 15(d) OF
THE
      SECURITIES EXCHANGE ACT OF 1934
Date
      of
      report (date of earliest event reported): June 8, 2006
COUGAR
      BIOTECHNOLOGY, INC.
(Exact
      name of registrant as specified in its charter)
Delaware
(State
      or
      other jurisdiction of incorporation)
000-51473
20-2903204
(Commission
                File Number)
(IRS
                Employer Identification No.)
10990
      Wilshire Blvd, Suite 1200
Los
      Angeles, CA 90024
(Address
      of principal executive offices) (Zip Code)
(310)
      943-8040
(Registrant's
      telephone number, including area code)
N/A
(Former
      name or former address, if changed since last report)
Check
      the
      appropriate box below if the Form 8-K filing is intended to simultaneously
      satisfy the filing obligation of the registrant under any of the following
      provisions:
o
Written communications
      pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
o
Soliciting material pursuant to Rule 14a-12 under the
      Exchange Act (17 CFR 240.14a-12)
o
Pre-commencement communications pursuant to Rule
      14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
o
Pre-commencement communications pursuant to Rule
      13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
1
Item
      5.02
Departure
      of Directors or Principal Officers; Election of Directors; Appointment of
      Principal Officers.
Effective
      June 8, 2006, the Board of Directors of Cougar Biotechnology, Inc. (the
"Company") appointed Michael S. Richman to the Company's Board of Directors.
      Since April 2002, Mr. Richman, age 45, has served as the Executive Vice
      President and Chief Operating Officer of MacroGenics, Inc., a privately held
      biotechnology company based in Rockville, Maryland that is engaged in the
      development of immune-based products, including monoclonal antibodies to treat
      patients with cancer, autoimmune disorders, allergy, or infectious diseases
      and
      vaccines to prevent infections in healthy individuals. From December 2000 to
      March 2002, Mr. Richman served as Senior Vice President, Corporate Development
      and Administration, for MedImmune, Inc. (NASDAQ: MEDI), a Gaithersburg, Maryland
      based company that is engaged in the development of immunotherapeutics focusing
      on infectious diseases, cancer and inflammatory diseases. From November 1996
      to
      December 2000, Mr. Richman served as Vice President, Business Development,
      for
      MedImmune, Inc. Mr. Richman holds an M.S.B.A in International Business from
      San
      Francisco State University and a B.S. from the University of California at
      Davis. The Company has not yet determined whether Mr. Richman will be named
      to
      any committees of the Board of Directors.
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SIGNATURE
Pursuant
      to the requirements of the Securities Exchange Act of 1934, the registrant
      has
      duly caused this report to be signed on its behalf by the undersigned hereunto
      duly authorized.
COUGAR
              BIOTECHNOLOGY, INC.
Date:
              June 13, 2006
By:
/s/ Alan
              H.
              Auerbach
Alan
              H. Auerbach
Chief
              Executive Officer and President
3