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      8-K</strong></font></div>
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      to Section 13 or 15(d) of the Securities Exchange Act of
      1934</strong></font></div>
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      of
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      February 23, 2006</strong></font></div>
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      MEDICAL SYSTEMS, INC.</strong></font></div>
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      the
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>Item
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 36pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">On
      February 23, 2006, RITA Medical Systems, Inc., a Delaware corporation (the
      &#8220;Company&#8221;), will announce its financial results for the quarter and year ended
      December 31, 2005. A copy of the Company's press release announcing and
      commenting upon these financial results is attached as Exhibit 99.1 hereto
      and
      incorporated by reference herein. </font></div>
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      Company uses, and this press release contains and the related conference call
      will include, the metrics of non-GAAP pro-forma loss for the quarter and year
      ended December 31, 2005 and the quarter and year ended December 31, 2004, and
      non-GAAP pro-forma loss outlook for the quarter ended March 31, 2006 and year
      ended December 31, 2006. The calculation of non-GAAP pro-forma loss has no
      basis
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      this press release non-GAAP measures of revenue for the fourth quarter ended
      December 31, 2004 and for the year ended December 31, 2004, and the metric
      earnings before interest, taxes, depreciation and amortization ("EBITDA") for
      the quarter and year ended December 31, 2005. The periods ended December 31,
      2004 include the revenue of Horizon Medical Products, Inc. for the period from
      July 1, 2004 through July 28, 2004, and for the period from January 1, 2004
      through July 28, 2004, respectively. Horizon's revenue for these periods is
      not
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      31,
      2004 or for the year ended December 31, 2004, because its merger with Horizon
      was not completed until July 29, 2004. This non-GAAP measure of revenue may
      be
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      meaningful comparison with revenue for the quarter and the year ended December
      31, 2005. The calculation of EBITDA has no basis in GAAP. The Company believes
      that all of these non-GAAP measures provide useful information to investors,
      permitting a better evaluation of the Company's ongoing business performance,
      including the evaluation of its performance against its competitors in the
      healthcare industry. A complete reconciliation of the non-GAAP financial
      measures for historical periods to the most directly comparable GAAP measures
      and EBITDA is presented in the accompanying tables, while this reconciliation
      for the Company&#8217;s 2006 outlook is presented above. </font></font></div>
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            </td>
            <td align="left" style="width: 27pt;"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><a href="v036340_ex99-1.htm">99.1</a></font></td>
            <td align="left">
              <div align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Press
                Release of RITA Medical Systems, Inc. dated February 23,
                2006</font></div>
            </td>
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        <div style="WIDTH: 100%; TEXT-ALIGN: center"><font style="DISPLAY: inline; FONT-SIZE: 8pt; FONT-FAMILY: ">-2-</font></div>
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    <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><strong>SIGNATURES</strong></font></div>
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      has
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      duly authorized.</font></div>
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          <tr valign="top" bgcolor="#ffffff">
            <td width="50%"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">&#160;</font></td>
            <td width="1%"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">&#160;</font></td>
            <td width="49%"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">&#160;</font></td>
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            <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">&#160;</font></td>
            <td colspan="2"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: "><strong>RITA
              MEDICAL SYSTEMS, INC.</strong></font></td>
          </tr>
          <tr valign="top" bgcolor="#ffffff">
            <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">&#160;<br>&#160;</font></td>
            <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">&#160;<br>&#160;</font></td>
            <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">&#160;<br>&#160;</font></td>
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            <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">Date:&#160;February
              23, 2006</font></td>
            <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">By:&#160;&#160;</font></td>
            <td><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">/s/&#160;MICHAEL
              D. ANGEL</font></td>
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            <td>
              <div><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">Name:&#160;&#160;
                Michael D. Angel</font></div>
              <div><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: ">Title:&#160;&#160;&#160;&#160;
                Chief Financial Officer</font></div>
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      MEDICAL SYSTEMS, INC.</strong></font></div>
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      TO EXHIBITS</strong></font></div>
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                Number</font></div>
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                Release of RITA Medical Systems, Inc. dated February 23,
                2006</font></div>
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{"company-data": {"conformed-name": "RITA MEDICAL SYSTEMS INC", "cik": "0001056421", "assigned-sic": "3845", "irs-number": "943199149", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "000-30959", "film-number": "06639880"}, "business-address": {"street1": "967 N SHORELINE BLVD", "city": "MOUNTAIN VIEW", "state": "CA", "zip": "94013", "phone": "6503858500"}, "mail-address": {"street1": "967 NORTH SHORELINE BLVD", "city": "MOUNTAIN VIEW", "state": "CA", "zip": "94043"}}
UNITED
      STATES
SECURITIES
      AND EXCHANGE COMMISSION
Washington,
      D.C. 20549
FORM
      8-K
Current
      Report
Pursuant
      to Section 13 or 15(d) of the Securities Exchange Act of
      1934
Date
      of
      Report
(Date
      of
      earliest event reported):
February 23, 2006
RITA
      MEDICAL SYSTEMS, INC.
(Exact
      name of registrant as specified in its charter)
000-30959
(Commission
      File Number)
Delaware
94-3199149
(State
                or other jurisdiction of incorporation)
(I.R.S.
                Employer Identification No.)
46421
      Landing Parkway
Fremont,
      CA 94538
(Address
      of principal executive offices, with zip code)
(510)
      771-0400
(Registrant's
      telephone number, including area code)
Check
      the
      appropriate box below if the Form 8-K filing is intended to simultaneously
      satisfy the filing obligation of the registrant under any of the following
      provisions (
see
General
      Instruction A.2. below):
o
Written
                communications pursuant to Rule 425 under the Securities Act (17
                CFR
                230.425)
o
Soliciting
                material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
                240.14a-12)
o
Pre-commencement
                communications pursuant to Rule 14d-2(b) under the Exchange Act (17
                CFR
                240.14d-2(b))
o
Pre-commencement
                communications pursuant to Rule 13e-4(c) under the Exchange Act (17
                CFR
                240.13e-4(c))
Item
      2.02
Results
      of Operations and Financial Condition.
On
      February 23, 2006, RITA Medical Systems, Inc., a Delaware corporation (the
      "Company"), will announce its financial results for the quarter and year ended
      December 31, 2005. A copy of the Company's press release announcing and
      commenting upon these financial results is attached as Exhibit 99.1 hereto
      and
      incorporated by reference herein.
The
      Company uses, and this press release contains and the related conference call
      will include, the metrics of non-GAAP pro-forma loss for the quarter and year
      ended December 31, 2005 and the quarter and year ended December 31, 2004, and
      non-GAAP pro-forma loss outlook for the quarter ended March 31, 2006 and year
      ended December 31, 2006. The calculation of non-GAAP pro-forma loss has no
      basis
      in GAAP. Additionally, the Company may use in the conference call related to
      this press release non-GAAP measures of revenue for the fourth quarter ended
      December 31, 2004 and for the year ended December 31, 2004, and the metric
      earnings before interest, taxes, depreciation and amortization ("EBITDA") for
      the quarter and year ended December 31, 2005. The periods ended December 31,
      2004 include the revenue of Horizon Medical Products, Inc. for the period from
      July 1, 2004 through July 28, 2004, and for the period from January 1, 2004
      through July 28, 2004, respectively. Horizon's revenue for these periods is
      not
      included in the Company's GAAP revenue for the fourth quarter ended December
      31,
      2004 or for the year ended December 31, 2004, because its merger with Horizon
      was not completed until July 29, 2004. This non-GAAP measure of revenue may
      be
      used in the conference call because management believes it facilitates a more
      meaningful comparison with revenue for the quarter and the year ended December
      31, 2005. The calculation of EBITDA has no basis in GAAP. The Company believes
      that all of these non-GAAP measures provide useful information to investors,
      permitting a better evaluation of the Company's ongoing business performance,
      including the evaluation of its performance against its competitors in the
      healthcare industry. A complete reconciliation of the non-GAAP financial
      measures for historical periods to the most directly comparable GAAP measures
      and EBITDA is presented in the accompanying tables, while this reconciliation
      for the Company's 2006 outlook is presented above.
Item
      9.01
Financial
      Statements and Exhibits.
(c)
Exhibits:
99.1
Press
                Release of RITA Medical Systems, Inc. dated February 23,
                2006
-2-
SIGNATURES
Pursuant
      to the requirements of the Securities Exchange Act of 1934, the Registrant
      has
      duly caused this report to be signed on its behalf by the undersigned hereunto
      duly authorized.
RITA
              MEDICAL SYSTEMS, INC.
Date: February
              23, 2006
By:
/s/ MICHAEL
              D. ANGEL
Name:  
                Michael D. Angel
Title:    
                Chief Financial Officer
-3-
RITA
      MEDICAL SYSTEMS, INC.
INDEX
      TO EXHIBITS
Exhibit
                Number
Description
99.1
Press
                Release of RITA Medical Systems, Inc. dated February 23,
                2006
-4-