UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT
     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

         Date of Report (Date of earliest event reported) June 19, 2006
                                                          -------------

                                 SyntheMed, Inc.
                                 ---------------
             (Exact name of Registrant as Specified in its Charter)


           Delaware                 0-20580            14-1745197
----------------------------    ----------------   -------------------
(State or Other Jurisdiction    (Commission file     (IRS Employer
      of Incorporation)              Number)       Identification No.)


200 Middlesex Essex Turnpike, Suite 210, Iselin, New Jersey     08830
-----------------------------------------------------------------------
         (Address of principal executive offices)            (Zip Code)

Registrant's telephone number, including area code: 732-404-1117

                   PO Box 219, Little Silver, New Jersey 07739
             ------------------------------------------------------
             (Former name or address, if changed since last report)


Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

|_|   Written communications pursuant to Rule 425 under the Securities Act (17
      CFR 230.425)

|_|   Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
      240.14a-12)

|_|   Pre-commencement communications pursuant to Rule 14d-2(b) under the
      Exchange Act (17 CFR 240.14d-2(b))

|_|   Pre-commencement communications pursuant to Rule 13e-4(c) under the
      Exchange Act (17 CFR 240.13e-4(c))


<PAGE>

Section 1 - Registrant's Business and Operations
Item 1.01 Entry into a Material Definitive Agreement.

Effective June 19, 2006, we amended and restated the employment agreements and
entered into change of control agreements with our executive officers, Mr.
Robert Hickey and Dr. Eli Pines. Mr. Hickey serves as our President, CEO and CFO
and as a member of our Board of Directors, and Dr. Pines serves as our Vice
President and Chief Scientific Officer. The initial term of Mr. Hickey's prior
employment agreement expired at the end of May 2006. As previously disclosed, in
March 2006 we entered into a new employment agreement with Dr. Pines when the
initial term of his prior employment agreement expired. The new changes to Dr.
Pines' employment agreement largely conform to changes made to Mr. Hickey's new
agreement.

Employment Agreements

The amended and restated employment agreements have an initial term of three
years from the date of the expiration of the initial term of the prior
agreements, May 29, 2006 for Mr. Hickey and March 1, 2006 for Dr. Pines. The
agreements are subject to automatic renewal thereafter for one-year periods
unless earlier terminated. Mr. Hickey is entitled to an annual base salary of
$291,052 and Dr. Pines is entitled to an annual base salary of $214,250, subject
to annual cost of living increases and such bonuses and stock options as the
Board of Directors shall determine. The executives have the right to participate
in, to the extent otherwise eligible under the terms thereof, the benefit plans
and programs, including medical and savings and retirement plans, and receive
the benefits and perquisites generally provided to employees of the same level
and responsibility. Each executive is entitled to agreed upon vacation. We are
required to obtain life insurance coverage on the life and for the benefit of
Mr. Hickey in an amount equal to a multiple of his base salary then in effect.

Under certain circumstances, we may become obligated to pay severance to the
executives under the employment agreements. These circumstances include (i) our
failure to renew the agreement at the expiration of the term, (ii) our
termination of executive's employment without cause and (iii) executive's
resignation for "good reason" (as defined in the agreements). The severance
obligation is equal to 12 months of base salary for Mr. Hickey and six months of
base salary for Dr. Pines. The severance obligation also includes the cost of
premiums for health insurance benefits that the executive would otherwise have
been entitled to receive during such period following termination of employment.
Each employment agreement contains confidentiality, ownership of intellectual
property, non-compete and non-solicitation provisions.

                                        2
<PAGE>

Change of Control Agreements

Effective June 19, 2006, we also entered into change of control agreements with
each of Mr. Hickey and Dr. Pines. The agreements are designed to help ensure
that our company will have the benefit of the continued services and dedication
of these executives, notwithstanding the possibility, threat or occurrence of a
change of control. Under the agreements, and subject to the terms thereof, the
executives will be entitled to certain payments and other benefits in the event
their employment is terminated or they resign for "good reason" in connection
with a "change of control" of our company, as those terms are defined in the
agreements. Subject to the terms of the agreements, these benefits and payments
generally include i) accelerating option vesting, (ii) extended option
exercisability notwithstanding termination of employment, (iii) continued
entitlement to participate in group health plans for a period of one year
following termination of employment at the same cost rate charged to
then-current employees and (iv) payment to the executive by our company in 12
equal monthly installments of (A) a multiple of the executive's highest base
salary in effect during the one-year preceding termination of employment and (B)
the greater of the previous year's annual bonus received by the executive or the
executive's current year target annual bonus. For Mr. Hickey the multiple is
200% and for Dr. Pines the multiple is 150%. Severance payments under the
employment agreements will reduce the severance payment obligations under the
change of control agreements.


                                   SIGNATURES

      Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                               SyntheMed, Inc.

Date:  June 23, 2006                           By:    /s/ Robert P. Hickey
                                                      ----------------------
                                                      Robert P. Hickey
                                                      President, CEO and CFO





                                        3
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UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT
     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

         Date of Report (Date of earliest event reported) June 19, 2006
                                                          -------------

                                 SyntheMed, Inc.
                                 ---------------
             (Exact name of Registrant as Specified in its Charter)

           Delaware                 0-20580            14-1745197
----------------------------    ----------------   -------------------
(State or Other Jurisdiction    (Commission file     (IRS Employer
      of Incorporation)              Number)       Identification No.)

200 Middlesex Essex Turnpike, Suite 210, Iselin, New Jersey     08830
-----------------------------------------------------------------------
         (Address of principal executive offices)            (Zip Code)

Registrant's telephone number, including area code: 732-404-1117

                   PO Box 219, Little Silver, New Jersey 07739
             ------------------------------------------------------
             (Former name or address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

|_|   Written communications pursuant to Rule 425 under the Securities Act (17
      CFR 230.425)

|_|   Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
      240.14a-12)

|_|   Pre-commencement communications pursuant to Rule 14d-2(b) under the
      Exchange Act (17 CFR 240.14d-2(b))

|_|   Pre-commencement communications pursuant to Rule 13e-4(c) under the
      Exchange Act (17 CFR 240.13e-4(c))
Section 1 - Registrant's Business and Operations
Item 1.01 Entry into a Material Definitive Agreement.

Effective June 19, 2006, we amended and restated the employment agreements and
entered into change of control agreements with our executive officers, Mr.
Robert Hickey and Dr. Eli Pines. Mr. Hickey serves as our President, CEO and CFO
and as a member of our Board of Directors, and Dr. Pines serves as our Vice
President and Chief Scientific Officer. The initial term of Mr. Hickey's prior
employment agreement expired at the end of May 2006. As previously disclosed, in
March 2006 we entered into a new employment agreement with Dr. Pines when the
initial term of his prior employment agreement expired. The new changes to Dr.
Pines' employment agreement largely conform to changes made to Mr. Hickey's new
agreement.

Employment Agreements

The amended and restated employment agreements have an initial term of three
years from the date of the expiration of the initial term of the prior
agreements, May 29, 2006 for Mr. Hickey and March 1, 2006 for Dr. Pines. The
agreements are subject to automatic renewal thereafter for one-year periods
unless earlier terminated. Mr. Hickey is entitled to an annual base salary of
$291,052 and Dr. Pines is entitled to an annual base salary of $214,250, subject
to annual cost of living increases and such bonuses and stock options as the
Board of Directors shall determine. The executives have the right to participate
in, to the extent otherwise eligible under the terms thereof, the benefit plans
and programs, including medical and savings and retirement plans, and receive
the benefits and perquisites generally provided to employees of the same level
and responsibility. Each executive is entitled to agreed upon vacation. We are
required to obtain life insurance coverage on the life and for the benefit of
Mr. Hickey in an amount equal to a multiple of his base salary then in effect.

Under certain circumstances, we may become obligated to pay severance to the
executives under the employment agreements. These circumstances include (i) our
failure to renew the agreement at the expiration of the term, (ii) our
termination of executive's employment without cause and (iii) executive's
resignation for "good reason" (as defined in the agreements). The severance
obligation is equal to 12 months of base salary for Mr. Hickey and six months of
base salary for Dr. Pines. The severance obligation also includes the cost of
premiums for health insurance benefits that the executive would otherwise have
been entitled to receive during such period following termination of employment.
Each employment agreement contains confidentiality, ownership of intellectual
property, non-compete and non-solicitation provisions.

                                        2
Change of Control Agreements

Effective June 19, 2006, we also entered into change of control agreements with
each of Mr. Hickey and Dr. Pines. The agreements are designed to help ensure
that our company will have the benefit of the continued services and dedication
of these executives, notwithstanding the possibility, threat or occurrence of a
change of control. Under the agreements, and subject to the terms thereof, the
executives will be entitled to certain payments and other benefits in the event
their employment is terminated or they resign for "good reason" in connection
with a "change of control" of our company, as those terms are defined in the
agreements. Subject to the terms of the agreements, these benefits and payments
generally include i) accelerating option vesting, (ii) extended option
exercisability notwithstanding termination of employment, (iii) continued
entitlement to participate in group health plans for a period of one year
following termination of employment at the same cost rate charged to
then-current employees and (iv) payment to the executive by our company in 12
equal monthly installments of (A) a multiple of the executive's highest base
salary in effect during the one-year preceding termination of employment and (B)
the greater of the previous year's annual bonus received by the executive or the
executive's current year target annual bonus. For Mr. Hickey the multiple is
200% and for Dr. Pines the multiple is 150%. Severance payments under the
employment agreements will reduce the severance payment obligations under the
change of control agreements.

                                   SIGNATURES

      Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                               SyntheMed, Inc.

Date:  June 23, 2006                           By:    /s/ Robert P. Hickey
                                                      ----------------------
                                                      Robert P. Hickey
                                                      President, CEO and CFO

                                        3