UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549


                                    FORM 8-K

                                 CURRENT REPORT

                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934


                        Date of Report: November 10, 2005
                                        -----------------
                        (Date of earliest event reported)


                          21ST CENTURY HOLDING COMPANY
                          ----------------------------
             (Exact name of registrant as specified in its charter)


         Florida                   0-2500111                   65-0248866
         -------                   ---------                   ----------
(State or other jurisdiction      (Commission               (I.R.S. Employer
     of incorporation)            File Number)             Identification No.)


       3661 West Oakland Park Blvd., Suite 300
                Lauderdale Lakes, FL                          33311
      ----------------------------------------              ----------
      (Address of principal executive offices)              (Zip Code)


       Registrant's telephone number, including area code: (954) 581-9993
                                                           --------------


                                 NOT APPLICABLE
          -------------------------------------------------------------
          (Former Name or Former Address, if Changed Since Last Report)

Check  the  appropriate  box  below  if the  Form  8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

|_|   Written  communications  pursuant to Rule 425 under the Securities Act (17
      CFR 230.425)

|_|   Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
      240.14a-12)

|_|   Pre-commencement  communications  pursuant  to  Rule  14d-2(b)  under  the
      Exchange Act (17 CFR 240.14d-2(b))

|_|   Pre-commencement  communications  pursuant  to  Rule  13e-4(c)  under  the
      Exchange Act (17 CFR 240.13e-4(c))


<PAGE>

Item 2.02     Results of Operations and Financial Condition.
              ----------------------------------------------

On November 10, 2005,  21st Century  Holding  Company (the  "Company")  issued a
press release to report its results for its fiscal  quarter ended  September 30,
2005. A copy of the press release is attached to this current report on Form 8-K
as Exhibit 99.1 and incorporated herein by reference.

The  information  in this Current  Report on Form 8-K and Exhibit 99.1  attached
hereto is hereby  intended to be  furnished  pursuant to Item 2.02,  "Results of
Operations and Financial  Condition." As provided in General  Instruction B.6 of
SEC Form 8-K,  such  information  shall not be deemed  "filed"  for  purposes of
Section 18 of the  Securities  Exchange Act of 1934,  as amended (the  "Exchange
Act"), or otherwise subject to the liabilities of that section, and it shall not
be deemed  incorporated  by reference in any filing under the  Securities Act of
1933, as amended,  or under the Exchange  Act,  whether made before or after the
date hereof,  except as expressly set forth by specific reference in such filing
to this Current Report on Form 8-K.

Item 9.01     Financial Statements and Exhibits.
              ----------------------------------

      (c)     Exhibits.
              ---------
      99.1    21st Century Holding Company Press Release, dated November 10,
                2005.


<PAGE>

                                   SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.


                                    21ST CENTURY HOLDING COMPANY


Date: November 10, 2005             By:    /s/ James Gordon Jennings, III
                                       -----------------------------------------
                                    Name:  James Gordon Jennings, III
                                    Title: Chief Financial Officer
                                    (Principal Accounting and Financial Officer)


<PAGE>

                                  EXHIBIT INDEX
                                  -------------

Exhibit No.     Exhibit Title
-----------     -------------
       99.1     21st Century Holding Company Press Release, dated November 10,
                  2005.
{"company-data": {"conformed-name": "21ST CENTURY HOLDING CO", "cik": "0001069996", "assigned-sic": "6331", "irs-number": "650248866", "state-of-incorporation": "FL", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "8-K", "act": "34", "file-number": "000-25001", "film-number": "051193864"}, "business-address": {"street1": "3661 WEST OAKLAND PARK BLVD", "street2": "SUITE 300", "city": "LAUDERDALE LAKES", "state": "FL", "zip": "33311", "phone": "9545819993"}, "mail-address": {"street1": "3661 WEST OAKLAND PARK BLVD", "street2": "SUITE 300", "city": "LAUDERDALE LAKES", "state": "FL", "zip": "33311"}}
UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT

                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934

                        Date of Report: November 10, 2005
                                        -----------------
                        (Date of earliest event reported)

                          21ST CENTURY HOLDING COMPANY
                          ----------------------------
             (Exact name of registrant as specified in its charter)

         Florida                   0-2500111                   65-0248866
         -------                   ---------                   ----------
(State or other jurisdiction      (Commission               (I.R.S. Employer
     of incorporation)            File Number)             Identification No.)

       3661 West Oakland Park Blvd., Suite 300
                Lauderdale Lakes, FL                          33311
      ----------------------------------------              ----------
      (Address of principal executive offices)              (Zip Code)

       Registrant's telephone number, including area code: (954) 581-9993
                                                           --------------

                                 NOT APPLICABLE
          -------------------------------------------------------------
          (Former Name or Former Address, if Changed Since Last Report)

Check  the  appropriate  box  below  if the  Form  8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

|_|   Written  communications  pursuant to Rule 425 under the Securities Act (17
      CFR 230.425)

|_|   Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
      240.14a-12)

|_|   Pre-commencement  communications  pursuant  to  Rule  14d-2(b)  under  the
      Exchange Act (17 CFR 240.14d-2(b))

|_|   Pre-commencement  communications  pursuant  to  Rule  13e-4(c)  under  the
      Exchange Act (17 CFR 240.13e-4(c))
Item 2.02     Results of Operations and Financial Condition.
              ----------------------------------------------

On November 10, 2005,  21st Century  Holding  Company (the  "Company")  issued a
press release to report its results for its fiscal  quarter ended  September 30,
2005. A copy of the press release is attached to this current report on Form 8-K
as Exhibit 99.1 and incorporated herein by reference.

The  information  in this Current  Report on Form 8-K and Exhibit 99.1  attached
hereto is hereby  intended to be  furnished  pursuant to Item 2.02,  "Results of
Operations and Financial  Condition." As provided in General  Instruction B.6 of
SEC Form 8-K,  such  information  shall not be deemed  "filed"  for  purposes of
Section 18 of the  Securities  Exchange Act of 1934,  as amended (the  "Exchange
Act"), or otherwise subject to the liabilities of that section, and it shall not
be deemed  incorporated  by reference in any filing under the  Securities Act of
1933, as amended,  or under the Exchange  Act,  whether made before or after the
date hereof,  except as expressly set forth by specific reference in such filing
to this Current Report on Form 8-K.

Item 9.01     Financial Statements and Exhibits.
              ----------------------------------

      (c)     Exhibits.
              ---------
      99.1    21st Century Holding Company Press Release, dated November 10,
                2005.
SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                    21ST CENTURY HOLDING COMPANY

Date: November 10, 2005             By:    /s/ James Gordon Jennings, III
                                       -----------------------------------------
                                    Name:  James Gordon Jennings, III
                                    Title: Chief Financial Officer
                                    (Principal Accounting and Financial Officer)
EXHIBIT INDEX
                                  -------------

Exhibit No.     Exhibit Title
-----------     -------------
       99.1     21st Century Holding Company Press Release, dated November 10,
                  2005.