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<TITLE>SANOFI-AVENTIS</TITLE>
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<FONT size="2">As Filed with the Securities and Exchange
Commission on December 23, 2004
</FONT>
</DIV>

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<FONT size="2">Registration No.:
333-&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</FONT>
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<B>UNITED STATES</B>

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<B>SECURITIES AND EXCHANGE COMMISSION</B>
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<B>Washington,&nbsp;D.C. 20549</B>
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 <B>Form&nbsp;S-8</B>

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<B>Registration Statement Under The Securities Act of 1933</B>
</DIV>

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<B><FONT size="4">Sanofi-Aventis</FONT></B>

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<FONT size="2">(Exact name of Registrant as Specified in its
Charter)
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    <TD width="57%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="40%"><FONT size="2">&nbsp;</FONT></TD>
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    <TD align="center" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <B><FONT size="2">Republic of France</FONT></B></DIV>
    </TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <B><FONT size="2">133529324</FONT></B></TD>
</TR>

<TR>
    <TD align="center" valign="top">
    <FONT size="2">(State or Other Jurisdiction of<BR>
    Incorporation or Organization)
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">(I.R.S. Employer<BR>
    Identification No.)
    </FONT></TD>
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<B><FONT size="2">174 avenue de France</FONT></B>

<DIV align="center">
<B><FONT size="2">75013 Paris, France</FONT></B>
</DIV>

<DIV align="center">
<FONT size="2">(Address of Principal Executive
</FONT>
</DIV>

<DIV align="center">
<FONT size="2">Offices and Zip Code)
</FONT>
</DIV>

<P align="center">
<B>Rh&#244;ne-Poulenc S.A. 1994 Stock Option Plan</B>

<DIV align="center">
<B>Rh&#244;ne-Poulenc S.A. 1995 Stock Option Plan</B>
</DIV>

<DIV align="center">
<B>Rh&#244;ne-Poulenc S.A. 1997 Stock Option Plan</B>
</DIV>

<DIV align="center">
<B>Rh&#244;ne-Poulenc Rorer Inc. 1995 Equity Compensation
Plan</B>
</DIV>

<DIV align="center">
<B>Rh&#244;ne-Poulenc Rorer Inc. Amended and Restated Stock
Plan</B>
</DIV>

<DIV align="center">
<B>Hoechst AG&nbsp;1999 Stock Option Plan</B>
</DIV>

<DIV align="center">
<B>1999/2000 Aventis Stock Option Plans</B>
</DIV>

<DIV align="center">
<B>Aventis 2000 Stock Option Plan</B>
</DIV>

<DIV align="center">
<B>Aventis Stock Option Plan 2001</B>
</DIV>

<DIV align="center">
<B>Aventis Stock Option Plan 2002</B>
</DIV>

<DIV align="center">
<B>Aventis Stock Option Plan 2003</B>
</DIV>

<DIV align="center">
<FONT size="2">(Full Titles of Plans)
</FONT>
</DIV>

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<B><FONT size="2"> Joseph Haggerty</FONT></B>

<DIV align="center">
<B><FONT size="2">Vice President and General Counsel</FONT></B>
</DIV>

<DIV align="center">
<B><FONT size="2">Aventis Pharmaceuticals</FONT></B>
</DIV>

<DIV align="center">
<B><FONT size="2">300 Somerset Corporate Boulevard</FONT></B>
</DIV>

<DIV align="center">
<B><FONT size="2">Bridgewater, New Jersey 08807</FONT></B>
</DIV>

<DIV align="center">
<FONT size="2">(Name and Address of Agent for Service)
</FONT>
</DIV>

<DIV align="center">
<B><FONT size="2">(908)&nbsp;243-6000</FONT></B>
</DIV>

<DIV align="center">
<FONT size="2">(Telephone Number, Including Area Code, of Agent
for Service)
</FONT>
</DIV>

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<HR size="1" width="30%" align="center" noshade>

<P align="center">
<I><FONT size="2">Copies to:</FONT></I>

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    <TD width="53%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="44%"><FONT size="2">&nbsp;</FONT></TD>
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<TR>
    <TD align="center" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <B><FONT size="2">Dirk Oldenburg<BR>
    Senior Vice President and General Counsel<BR>
    Sanofi-Aventis<BR>
    174 avenue de France<BR>
    75013, Paris, France<BR>
    + 33 1 53 77 40 00</FONT></B></DIV>
    </TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <B><FONT size="2">David A. Katz<BR>
    Wachtell, Lipton, Rosen&nbsp;&#38; Katz<BR>
    51 West 52nd&nbsp;Street<BR>
    New York, NY 10019<BR>
    (212) 403 1000</FONT></B></TD>
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<DIV align="center">
<B><FONT size="2">Calculation of Registration Fee</FONT></B>
</DIV>
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    <TD width="47%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="5%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="1%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="4%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="5%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="1%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="4%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="5%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="1%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="4%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="5%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="1%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="5%"><FONT size="2">&nbsp;</FONT></TD>
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<TR>
    <TD></TD>
    <TD></TD>
    <TD colspan="3"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Proposed</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Proposed</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD></TD>
    <TD></TD>
    <TD colspan="3"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Maximum</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Maximum</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Amount</FONT></B></TD>
</TR>

<TR>
    <TD align="center" nowrap><B><FONT size="1">Title of Each Class of</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Amount to</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Offering</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Aggregate</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">of</FONT></B></TD>
</TR>

<TR>
    <TD align="center" nowrap><B><FONT size="1">Securities to Be</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">be</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Price</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Offering</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Registration</FONT></B></TD>
</TR>

<TR>
    <TD align="center" nowrap><B><FONT size="1">Registered</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Registered(1)</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Per Share(2)</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Price(3)</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Fee(4)</FONT></B></TD>
</TR>

<TR>
    <TD colspan="17"></TD>
</TR>

<TR>
    <TD colspan="17" align="center" nowrap><HR size="1" noshade></TD>
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<TR>
    <TD align="left" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <FONT size="2">Sanofi-Aventis Ordinary Shares, nominal value
    <FONT face="times new roman,times">&#128;</FONT>2
    </FONT></DIV>
    </TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="2">27,485,695</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="2">$73.17</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="2">$2,011,128,304</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="2">$236,710</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>

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</DIV>

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<HR size="1" width="18%" align="left" noshade>
<P>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">

<TR>
    <TD width="4%"></TD>
    <TD width="96%"></TD>
</TR>

<TR valign="top">
    <TD><FONT size="2">(1)</FONT></TD>
    <TD align="left">
    <FONT size="2">In each case the number of Sanofi-Aventis
    ordinary shares registered is based on the number of Aventis
    ordinary shares subject to outstanding options that are to be
    assumed by Sanofi-Aventis in the merger after adjustment to give
    effect to the merger exchange ratio of 27 Sanofi-Aventis
    ordinary shares for 23 Aventis ordinary shares. See Explanatory
    Note.
    </FONT></TD>
</TR>

<TR>
    <TD>&nbsp;</TD>
</TR>

<TR valign="top">
    <TD><FONT size="2">(2)</FONT></TD>
    <TD align="left">
    <FONT size="2">Calculated solely for the purposes of this
    offering under Rule&nbsp;457(h) of the Securities Act of 1933,
    on the basis of the weighted average exercise price of the
    outstanding options to be assumed by Sanofi-Aventis in the
    merger, in each case after adjustment to give effect to the
    merger exchange ratio of 27 Sanofi-Aventis ordinary shares for
    23 Aventis ordinary shares. See Explanatory Note. The adjusted
    exercise prices of the options have been converted into
    U.S.&nbsp;dollars on the basis of an exchange rate of 1 euro =
    $1.3390, which was the Federal Reserve Bank of New York noon
    buying rate on December 22, 2004.
    </FONT></TD>
</TR>

<TR>
    <TD>&nbsp;</TD>
</TR>

<TR valign="top">
    <TD><FONT size="2">(3)</FONT></TD>
    <TD align="left">
    <FONT size="2">Calculated as the product of (x)&nbsp;the number
    of Sanofi-Aventis ordinary shares to be registered and
    (y)&nbsp;the weighted average exercise price of the options
    assumed.
    </FONT></TD>
</TR>

<TR>
    <TD>&nbsp;</TD>
</TR>

<TR valign="top">
    <TD><FONT size="2">(4)</FONT></TD>
    <TD align="left">
    <FONT size="2">Calculated as the product of (x)&nbsp;0.0001177
    and (y)&nbsp;the Proposed Maximum Aggregate Offering Price.
    </FONT></TD>
</TR>

</TABLE>

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<HR size="1" noshade color="#000000" style="margin-top: -2px">

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<HR size="4" noshade color="#000000" style="margin-top: -10px">
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<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<P align="center">
<B><FONT size="2">EXPLANATORY NOTE</FONT></B>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">On October&nbsp;14, 2004, Sanofi-Aventis, a
French <I>soci&#233;t&#233; anonyme,</I> and Aventis, a French
<I>soci&#233;t&#233; anonyme </I>and subsidiary of
Sanofi-Aventis in which Sanofi-Aventis holds 97.98% of the share
capital, entered into an Agreement and Plan of Merger (the
&#147;Merger Agreement&#148;), pursuant to which, among other
things, Aventis will merge with and into Sanofi-Aventis (the
&#147;Merger&#148;). As a result of the Merger, Sanofi-Aventis
will continue as the surviving company, Aventis will be
dissolved and the shareholders of Aventis (other than Aventis
and Sanofi-Aventis) will receive 27 Sanofi-Aventis ordinary
shares, nominal value
<FONT face="times new roman,times">&#128;</FONT>2&nbsp;per
share, for every 23 Aventis ordinary shares, nominal value
<FONT face="times new roman,times">&#128;</FONT>3.82&nbsp;per
share, that they hold (such ratio, the &#147;Merger Exchange
Ratio&#148;). For legal purposes, the Merger Agreement provides
that the Merger will be effective as of December&nbsp;31, 2004.
</FONT>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">On December&nbsp;13, 2004, at a combined ordinary
and extraordinary general meeting, the shareholders of Aventis
voted to approve the Merger Agreement, the Merger and the
dissolution of Aventis. On December&nbsp;23, 2004, at an
extraordinary general meeting, the shareholders of
Sanofi-Aventis voted to approve the Merger Agreement and the
Merger, as well as the increase in the share capital of
Sanofi-Aventis and the issuance of the new Sanofi-Aventis
ordinary shares to be issued in payment of the merger
consideration.
</FONT>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">The Merger Agreement expressly provides that
Sanofi-Aventis, as successor to Aventis, agrees to be bound by
Aventis&#146;s obligations under the Aventis subscription stock
options. After the effective time of the Merger, the Aventis
subscription stock options will entitle their holders to
subscribe for Sanofi-Aventis ordinary shares instead of Aventis
ordinary shares. The number of shares subject to the options and
their exercise price will be adjusted to give effect to the
Merger Exchange Ratio in the following manner:
</FONT>
<P>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">

<TR>
    <TD width="3%"></TD>
    <TD width="4%"></TD>
    <TD width="93%"></TD>
</TR>

<TR valign="top">
    <TD>&nbsp;</TD>
    <TD><FONT size="2"> &#149;</FONT></TD>
    <TD align="left">
    <FONT size="2">the number of Sanofi-Aventis ordinary shares that
    each holder of Sanofi-Aventis options shall have the right to
    subscribe under any given subscription option plan shall equal
    that number of Aventis ordinary shares that could formerly have
    been subscribed under that plan multiplied by the Merger
    Exchange Ratio of 27/23 (or approximately 1.17391) applicable to
    shareholders, rounded down to the nearest whole number;&nbsp;and
    </FONT></TD>
</TR>

<TR>
    <TD>&nbsp;</TD>
</TR>

<TR valign="top">
    <TD>&nbsp;</TD>
    <TD><FONT size="2"> &#149;</FONT></TD>
    <TD align="left">
    <FONT size="2">the exercise price per Sanofi-Aventis ordinary
    share shall be equal to the exercise price per Aventis ordinary
    share divided by the Merger Exchange Ratio of 27/23 (or
    approximately 1.17391) applicable to shareholders, rounded down
    to the nearest whole euro centime;
    </FONT></TD>
</TR>

</TABLE>

<P align="left">
<FONT size="2">with all other terms of exercise remaining
unaltered.
</FONT>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">At the extraordinary general meeting on
December&nbsp;31, 2004, Sanofi-Aventis shareholders voted to
waive their preferential subscription rights with respect to the
Sanofi-Aventis ordinary shares that will be issued on the
exercise of the Aventis subscription stock options assumed by
Sanofi-Aventis.
</FONT>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">With respect to the purchase option plans issued
by Aventis Inc. (formerly known as Rh&#244;ne-Poulenc Rorer,
Inc.) and Hoechst which provide for the purchase of Aventis
shares, the Merger Agreement provides that Sanofi-Aventis shall
cause the regulations of these plans to be amended to provide
that, after the effective time of the Merger, holders of these
purchase options may purchase Sanofi-Aventis shares after
adjusting the purchase price and the number of shares subject to
option by the Merger Exchange Ratio in the same manner as set
forth above, with all other terms of exercise remaining
unaltered.
</FONT>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">Accordingly, this Registration Statement on
Form&nbsp;S-8 registers the aggregate number of Sanofi-Aventis
ordinary shares that may be issued on the exercise of
outstanding Aventis subscription stock options held by U.S
holders. The following table sets forth (i)&nbsp;the date of the
grant, (ii)&nbsp;the number of unexercised subscription stock
options held by U.S.&nbsp;holders, (iii)&nbsp;the original
exercise price of the options, (iv)&nbsp;the number of
Sanofi-Aventis ordinary shares for which the options may be
exercised after the Merger and which are being registered
pursuant to this Registration Statement and (v)&nbsp;the
adjusted exercise price:
</FONT>
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<CENTER>
<TABLE width="100%" align="center" cellspacing="0" cellpadding="0" border="0">

<TR>
    <TD width="21%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="8%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="1%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="7%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="8%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="1%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="8%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="8%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="1%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="7%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="9%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="1%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="8%"><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17"></TD>
</TR>

<TR>
    <TD colspan="17" align="center" nowrap><HR size="1" noshade></TD>
</TR>

<TR>
    <TD colspan="9"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Number of Sanofi-</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD colspan="9"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Aventis ordinary shares</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD colspan="9"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">to be issued on</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD colspan="9"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">exercise</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Number of Aventis</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">of options after the</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">ordinary shares subject</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Merger and registered</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">to outstanding options</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">pursuant to this</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD align="center" nowrap><B><FONT size="1">Date of Original Grant</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">held by U.S.&nbsp;holders</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Original Exercise Price</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Registration Statement</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Adjusted Exercise Price</FONT></B></TD>
</TR>

<TR>
    <TD colspan="17"></TD>
</TR>

<TR>
    <TD colspan="17" align="center" nowrap><HR size="1" noshade></TD>
</TR>

<TR valign="bottom" bgcolor="#EEEEEE">
    <TD align="left" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <FONT size="1">February&nbsp;7, 1995
    </FONT></DIV>
    </TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">8,500</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>17.66</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">9,978</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>15.04</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17" align="left"><HR size="1" noshade></TD>

</TR>

<TR>
    <TD align="left" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <FONT size="1">December&nbsp;14, 1995
    </FONT></DIV>
    </TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">10,000</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>15.40</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">11,739</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>13.11</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17" align="left"><HR size="1" noshade></TD>

</TR>

<TR valign="bottom" bgcolor="#EEEEEE">
    <TD align="left" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <FONT size="1">December&nbsp;17, 1996
    </FONT></DIV>
    </TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">17,500</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>23.53</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">20,543</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>20.04</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17" align="left"><HR size="1" noshade></TD>

</TR>

<TR>
    <TD align="left" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <FONT size="1">December&nbsp;16, 1997
    </FONT></DIV>
    </TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">291,647</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>37.75</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">342,368</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>32.15</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17" align="left"><HR size="1" noshade></TD>

</TR>

<TR valign="bottom" bgcolor="#EEEEEE">
    <TD align="left" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <FONT size="1">December&nbsp;15, 1998
    </FONT></DIV>
    </TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">639,433</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>40.08</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">750,639</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>34.14</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17" align="left"><HR size="1" noshade></TD>

</TR>

<TR>
    <TD align="left" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <FONT size="1">February&nbsp;15, 1999
    </FONT></DIV>
    </TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">1,340,575</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>58.75</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">1,573,718</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>50.04</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17" align="left"><HR size="1" noshade></TD>

</TR>

<TR valign="bottom" bgcolor="#EEEEEE">
    <TD align="left" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <FONT size="1">May&nbsp;11, 2000
    </FONT></DIV>
    </TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">240,520</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>58.29</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">282,350</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>49.65</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17" align="left"><HR size="1" noshade></TD>

</TR>

<TR>
    <TD align="left" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <FONT size="1">November&nbsp;14, 2000
    </FONT></DIV>
    </TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">4,573,466</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>79.75</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">5,368,851</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>67.93</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17" align="left"><HR size="1" noshade></TD>

</TR>

<TR valign="bottom" bgcolor="#EEEEEE">
    <TD align="left" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <FONT size="1">March&nbsp;29, 2001
    </FONT></DIV>
    </TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">53,250</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>80.94</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">62,511</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>68.94</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17" align="left"><HR size="1" noshade></TD>

</TR>

<TR>
    <TD align="left" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <FONT size="1">November&nbsp;7, 2001
    </FONT></DIV>
    </TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">4,659,375</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>83.81</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">5,469,701</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>71.39</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17" align="left"><HR size="1" noshade></TD>

</TR>

<TR valign="bottom" bgcolor="#EEEEEE">
    <TD align="left" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <FONT size="1">November&nbsp;12, 2002
    </FONT></DIV>
    </TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">5,160,200</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>60.27</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">6,057,626</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>51.34</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17" align="left"><HR size="1" noshade></TD>

</TR>

<TR>
    <TD align="left" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <FONT size="1">December&nbsp;2, 2003
    </FONT></DIV>
    </TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">6,006,955</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>47.52</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">7,051,643</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>40.48</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17" align="left"><HR size="1" noshade></TD>

</TR>

<TR valign="bottom" bgcolor="#EEEEEE">
    <TD align="left" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <B><FONT size="1">Total/ wt. average</FONT></B></DIV>
    </TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><B><FONT size="1">23,001,421</FONT></B></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><B><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>64.61</FONT></B></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><B><FONT size="1">27,001,668</FONT></B></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><B><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>55.04</FONT></B></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17" align="left"><HR size="1" noshade></TD>

</TR>

</TABLE>
</CENTER>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">This Registration Statement also registers the
aggregate number of Sanofi-Aventis ordinary shares that may be
purchased on the exercise of outstanding purchase stock options
held by U.S. holders issued under the option plans of Aventis
Inc. (formerly known as Rh&#244;ne-Poulenc Rorer Inc.). The
following table sets forth the same data as above with respect
to these purchase options:
</FONT>

<CENTER>
<TABLE width="100%" align="center" cellspacing="0" cellpadding="0" border="0">

<TR>
    <TD width="21%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="8%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="1%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="7%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="8%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="1%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="8%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="8%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="1%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="7%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="9%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="1%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="8%"><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17"></TD>
</TR>

<TR>
    <TD colspan="17" align="center" nowrap><HR size="1" noshade></TD>
</TR>

<TR>
    <TD colspan="9"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Number of Sanofi-</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD colspan="9"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Aventis ordinary shares</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD colspan="9"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">to be issued on</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD colspan="9"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">exercise</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Number of Aventis</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">of options after the</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">ordinary shares subject</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Merger and registered</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">to outstanding options</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">pursuant to this</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD align="center" nowrap><B><FONT size="1">Date of Original Grant</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">held by U.S.&nbsp;holders</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Original Exercise Price</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Registration Statement</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Adjusted Exercise Price</FONT></B></TD>
</TR>

<TR>
    <TD colspan="17"></TD>
</TR>

<TR>
    <TD colspan="17" align="center" nowrap><HR size="1" noshade></TD>
</TR>

<TR>
    <TD align="left" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <FONT size="1">February&nbsp;27, 1995
    </FONT></DIV>
    </TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">30,017</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom"><FONT size="1">$</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">16.67</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">35,237</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom"><FONT size="1">$</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">14.20</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17" align="left"><HR size="1" noshade></TD>

</TR>

<TR>
    <TD align="left" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <FONT size="1">February&nbsp;27, 1996
    </FONT></DIV>
    </TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">44,554</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom"><FONT size="1">$</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">26.67</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">52,303</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom"><FONT size="1">$</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">22.71</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17" align="left"><HR size="1" noshade></TD>

</TR>

<TR>
    <TD align="left" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <FONT size="1">February&nbsp;20, 1997
    </FONT></DIV>
    </TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">64,546</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom"><FONT size="1">$</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">30.68</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">75,771</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom"><FONT size="1">$</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">26.13</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17" align="left"><HR size="1" noshade></TD>

</TR>

<TR>
    <TD align="left" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <B><FONT size="1">Total/wt average</FONT></B></DIV>
    </TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><B><FONT size="1">139,117</FONT></B></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom"><B><FONT size="1">$</FONT></B></TD>
    <TD align="right" valign="bottom" nowrap><B><FONT size="1">26.37</FONT></B></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><B><FONT size="1">163,311</FONT></B></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom"><B><FONT size="1">$</FONT></B></TD>
    <TD align="right" valign="bottom" nowrap><B><FONT size="1">22.46</FONT></B></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17" align="left"><HR size="1" noshade></TD>

</TR>

</TABLE>
</CENTER>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">This Registration Statement also registers the
aggregate number of Sanofi-Aventis ordinary shares that may be
purchased on the exercise of outstanding purchase stock options
held by U.S. holders issued under the option plans of Hoechst.
The following table sets forth the same data as above with
respect to these purchase options:
</FONT>

<CENTER>
<TABLE width="100%" align="center" cellspacing="0" cellpadding="0" border="0">

<TR>
    <TD width="21%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="8%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="1%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="7%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="8%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="1%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="8%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="8%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="1%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="7%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="9%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="1%"><FONT size="1">&nbsp;</FONT></TD>
    <TD width="8%"><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17"></TD>
</TR>

<TR>
    <TD colspan="17" align="center" nowrap><HR size="1" noshade></TD>
</TR>

<TR>
    <TD colspan="9"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Number of Sanofi-</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD colspan="9"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Aventis ordinary shares</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD colspan="9"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">to be issued on</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD colspan="9"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">exercise</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Number of Aventis</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">of options after the</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">ordinary shares subject</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Merger and registered</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">to outstanding options</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">pursuant to this</FONT></B></TD>
    <TD></TD>
    <TD colspan="3"></TD>
</TR>

<TR>
    <TD align="center" nowrap><B><FONT size="1">Date of Original Grant</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">held by U.S.&nbsp;holders</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Original Exercise Price</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Registration Statement</FONT></B></TD>
    <TD></TD>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Adjusted Exercise Price</FONT></B></TD>
</TR>

<TR>
    <TD colspan="17"></TD>
</TR>

<TR>
    <TD colspan="17" align="center" nowrap><HR size="1" noshade></TD>
</TR>

<TR>
    <TD align="left" valign="top">
    <DIV style="margin-left:10px; text-indent:-10px">
    <FONT size="1">September&nbsp;7, 1999
    </FONT></DIV>
    </TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">273,202</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>48.43</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1">320,715</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
    <TD align="right" valign="bottom" nowrap><FONT size="1"><FONT face="times new roman,times">&#128;</FONT>41.25</FONT></TD>
    <TD><FONT size="1">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="17" align="left"><HR size="1" noshade></TD>

</TR>

</TABLE>
</CENTER>
<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<P align="center">
<B><FONT size="2">PART&nbsp;I</FONT></B>

<P align="center">
<B><FONT size="2">INFORMATION REQUIRED IN THE
PROSPECTUS</FONT></B>

<DIV>&nbsp;</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">

<TR>
    <TD width="9%"></TD>
    <TD width="91%"></TD>
</TR>

<TR valign="top">
    <TD><B><FONT size="2">Item&nbsp;1.</FONT></B></TD>
    <TD>
    <B><FONT size="2">Plan Information</FONT></B></TD>
</TR>

</TABLE>

<P align="left">
<FONT size="2">Omitted pursuant to the instructions and
provisions of Form&nbsp;S-8.
</FONT>

<DIV>&nbsp;</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">

<TR>
    <TD width="9%"></TD>
    <TD width="91%"></TD>
</TR>

<TR valign="top">
    <TD><B><FONT size="2">Item&nbsp;2.</FONT></B></TD>
    <TD>
    <B><FONT size="2">Registrant Information and Employee Plan
    Annual Information</FONT></B></TD>
</TR>

</TABLE>

<P align="left">
<FONT size="2">Omitted pursuant to the instructions and
provisions of Form&nbsp;S-8.
</FONT>

<P align="center">
<B><FONT size="2">PART&nbsp;II</FONT></B>

<P align="center">
<B><FONT size="2">INFORMATION REQUIRED IN THE REGISTRATION
STATEMENT</FONT></B>

<DIV>&nbsp;</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">

<TR>
    <TD width="9%"></TD>
    <TD width="91%"></TD>
</TR>

<TR valign="top">
    <TD><B><FONT size="2">Item&nbsp;3.</FONT></B></TD>
    <TD>
    <B><FONT size="2">Incorporation of Documents by
    Reference</FONT></B></TD>
</TR>

</TABLE>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">This Registration Statement on Form&nbsp;S-8
hereby incorporates by reference the contents of the following
reports of Sanofi-Aventis (the &#147;Registrant&#148;, formerly
known as Sanofi-Synth&#233;labo) filed with, or furnished to,
the Securities and Exchange Commission (the
&#147;Commission&#148;) pursuant to the Securities Exchange Act
of 1934, as amended (the &#147;Exchange Act&#148;):
</FONT>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">(a)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Annual
Report on Form&nbsp;20-F of the Registrant for the year ended
December&nbsp;31, 2003 (the &#147;Form&nbsp;20-F&#148;)
(Commission file No.&nbsp;001-31368);
</FONT>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">(b)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Reports on
Form&nbsp;6-K furnished by the Registrant (whether under the
names Sanofi-Synth&#233;labo or Sanofi-Aventis) to the
Commission pursuant to Section&nbsp;13(a) or 15(d) of the
Exchange Act on the following dates: January&nbsp;7, 2004,
January&nbsp;8, 2004, January&nbsp;12, 2004, January&nbsp;20,
2004, January&nbsp;29, 2004, February&nbsp;4, 2004,
February&nbsp;16, 2004, March&nbsp;9, 2004, March&nbsp;10, 2004,
March&nbsp;19, 2004, March&nbsp;23, 2004, March&nbsp;31, 2004,
April&nbsp;5, 2004, April&nbsp;12, 2004, April&nbsp;13, 2004,
April&nbsp;15, 2004, April&nbsp;22, 2004, April&nbsp;26, 2004,
April&nbsp;27, 2004, May&nbsp;4, 2004, May&nbsp;5, 2004,
May&nbsp;14, 2004, May&nbsp;21, 2004, May&nbsp;26, 2004,
June&nbsp;2, 2004, June&nbsp;&nbsp;4, 2004, June&nbsp;14, 2004,
June&nbsp;22, 2004, June&nbsp;24, 2004, June&nbsp;25, 2004,
July&nbsp;15, 2004 (two reports), July&nbsp;21, 2004,
July&nbsp;29, 2004, August&nbsp;2, 2004, August&nbsp;9, 2004,
August&nbsp;12, 2004, August&nbsp;13, 2004, August&nbsp;19,
2004, August&nbsp;24, 2004, August&nbsp;31, 2004,
September&nbsp;7, 2004, September&nbsp;14, 2004,
September&nbsp;16, 2004, September&nbsp;17, 2004, September 22
(two reports), October&nbsp;8, 2004 (report relating to
Actonel&#174; press release), October&nbsp;14, 2004,
November&nbsp;5, 2004 (report relating to Taxotere&#174; and
Eloxatin&#174; press releases); November&nbsp;9, 2004;
November&nbsp;24, 2004, November&nbsp;26, 2004 (report relating
to press release regarding relocation of Aventis headquarters),
November&nbsp;30, 2004, December&nbsp;9, 2004 (report relating
to press release regarding U.S.&nbsp;intellectual property
litigation); December&nbsp;10, 2004; December&nbsp;16, 2004
(report relating to financial calendar of Sanofi-Aventis);
December&nbsp;20, 2004; December&nbsp;22, 2004 and
December&nbsp;23, 2004;
</FONT>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">(c)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The description
of the Registrant&#146;s ordinary shares, nominal
value&nbsp;<FONT face="times new roman,times">&#128;</FONT>2&nbsp;per
share, set forth under the captions &#147;A. Share Capital&#148;
and &#147;B. Memorandum and Articles of Association&#148; in
Item&nbsp;10 of the Registrant&#146;s Registration Statement on
Form&nbsp;20-F (Commission file No.&nbsp;001-31368), filed with
the Commission on June&nbsp;25, 2002 and the updated
descriptions of the Registrant&#146;s ordinary shares and
American depositary shares contained in the Post-Effective
Amendment No.&nbsp;3 to the Registration Statement on
Form&nbsp;F-4 (Registration No.&nbsp;333-112314) (the
&#147;Form&nbsp;F-4&#148;) filed by the Registrant with the
Commission on November&nbsp;9, 2004, under the captions
&#147;Description Of Sanofi-Aventis Ordinary Shares&#148; and
&#147;Description Of Sanofi-Aventis American Depositary
Shares&#148;, including any amendment or report filed for the
purpose of updating such description;&nbsp;and
</FONT>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">(d)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;All documents
filed by the Registrant with the Commission pursuant to
Sections&nbsp;13(a), 13(c),&nbsp;14, or 15(d) of the Exchange
Act prior to the filing of a post-effective amendment indicating
that all securities offered have been sold or that deregisters
all securities then remaining unsold shall be deemed to be
incorporated by reference in this Registration Statement and to
be a part hereof from the date of filing of such documents
reference. Statements contained in the foregoing documents
incorporated by reference shall be deemed to be modified or
superseded hereby to the extent that statements contained in the
Prospectus, or in any subsequently filed documents that are
amendments hereto or that are incorporated herein by reference,
shall modify or replace such statements.
</FONT>
<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV>&nbsp;</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">

<TR>
    <TD width="9%"></TD>
    <TD width="91%"></TD>
</TR>

<TR valign="top">
    <TD><B><FONT size="2">Item&nbsp;4.</FONT></B></TD>
    <TD>
    <B><FONT size="2">Description of Securities</FONT></B></TD>
</TR>

</TABLE>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">The information required by Item&nbsp;4 is not
applicable to this Registration Statement because the class of
securities to be offered is registered under Section&nbsp;12 of
the Exchange Act.
</FONT>

<DIV>&nbsp;</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">

<TR>
    <TD width="9%"></TD>
    <TD width="91%"></TD>
</TR>

<TR valign="top">
    <TD><B><FONT size="2">Item&nbsp;5.</FONT></B></TD>
    <TD>
    <B><FONT size="2">Interests of named Experts and
    Counsel</FONT></B></TD>
</TR>

</TABLE>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">The information required by Item&nbsp;5 is not
applicable to this Registration Statement.
</FONT>

<DIV>&nbsp;</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">

<TR>
    <TD width="9%"></TD>
    <TD width="91%"></TD>
</TR>

<TR valign="top">
    <TD><B><FONT size="2">Item&nbsp;6.</FONT></B></TD>
    <TD>
    <B><FONT size="2">Indemnification of Directors and
    Officers</FONT></B></TD>
</TR>

</TABLE>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">The French Commercial Code prohibits provisions
of <I>statuts </I>that limit the liability of directors.
However, if a director is sued by a third party and ultimately
prevails in the litigation on all counts, but is nevertheless
required to bear attorneys&#146; fees and costs, the company may
reimburse those fees and costs pursuant to an indemnification
arrangement with the director.
</FONT>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">Under French law a company may purchase directors
and officers&#146; insurance for all or part of the members of
its management. A French corporation is responsible to third
parties for the consequences of the decisions of its board of
directors. However, if those decisions qualify as mismanagement,
the relevant member of the board of directors may have to fully
or partly indemnify the company. Sanofi-Aventis has purchased
insurance for all of its directors.
</FONT>

<DIV>&nbsp;</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">

<TR>
    <TD width="9%"></TD>
    <TD width="91%"></TD>
</TR>

<TR valign="top">
    <TD><B><FONT size="2">Item&nbsp;7.</FONT></B></TD>
    <TD>
    <B><FONT size="2">Exemption from Registration Claimed</FONT></B></TD>
</TR>

</TABLE>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">The information required by Item&nbsp;7 is not
applicable to this Registration Statement.
</FONT>

<DIV>&nbsp;</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">

<TR>
    <TD width="9%"></TD>
    <TD width="91%"></TD>
</TR>

<TR valign="top">
    <TD><B><FONT size="2">Item&nbsp;8.</FONT></B></TD>
    <TD>
    <B><FONT size="2">Exhibits</FONT></B></TD>
</TR>

</TABLE>

<CENTER>
<TABLE width="100%" align="center" cellspacing="0" cellpadding="0" border="0">

<TR>
    <TD width="8%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="1%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="7%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="81%"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.1</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Bylaws (<I>statuts</I>) of Sanofi-Aventis
    (incorporated herein by reference to Exhibit&nbsp;3.1 of
    Post-Effective Amendment No.&nbsp;2 to the Registration
    Statement on Form&nbsp;F-4 (Registration No.&nbsp;333-112314) as
    filed by the Registrant with the Commission on October&nbsp;15,
    2004)
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.2</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Deposit Agreement (including the form of
    depositary receipt) between the Registrant and The Bank of New
    York, as depositary (incorporated herein by reference to
    Exhibit&nbsp;A to the Registration Statement on Form&nbsp;F-6
    (Registration No.&nbsp;333-116262) relating to American
    Depositary Shares, filed on June&nbsp;8, 2004)
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.3</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Rules and Regulations for Aventis Stock Option
    Plan 2003
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.4</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Rules and Regulations for Aventis Stock Option
    Plan 2002
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.5</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Rules and Regulations for Aventis Stock Option
    Plan 2001
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.6</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Rules and Regulations for Aventis 2000 Stock
    Option Plan
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.7</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Description of the Aventis 1999/2000 Stock Option
    Plan
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.8</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Description of the Hoechst AG&nbsp;1999 Stock
    Option Plan
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.9</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Forms of grant notice (Participation Forms) under
    the Hoechst AG&nbsp;1999 Stock Option Plan
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.10</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Hoechst 1999 Stock Option Continuity Plan
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.11</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Rh&#244;ne-Poulenc Rorer Inc. 1995 Equity
    Compensation Plan
    </FONT></TD>
</TR>

</TABLE>
</CENTER>

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<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<CENTER>
<TABLE width="100%" align="center" cellspacing="0" cellpadding="0" border="0">

<TR>
    <TD width="8%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="1%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="7%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="81%"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.12</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Rh&#244;ne-Poulenc Rorer Inc. Amended and
    Restated Stock Option Plan
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.13</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Rh&#244;ne-Poulenc S.A. 1994 Stock Option Plan
    (as authorized at the Ordinary and Extraordinary Metting of
    Shareholders held on April&nbsp;22, 1994)
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.14</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Rh&#244;ne-Poulenc S.A. 1995 Stock Option Plan
    (as authorized at the Ordinary and Extraordinary Metting of
    Shareholders held on April&nbsp;13, 1995)
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.15</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Rh&#244;ne-Poulenc S.A. 1997 Stock Option Plan
    (as authorized at the Ordinary and Extraordinary Metting of
    Shareholders held on April&nbsp;23, 1997)
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.16</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Letter to Aventis option holders regarding the
    conversion of options into options on Sanofi-Aventis ordinary
    shares (Citigroup administered plans)
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.17</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Letter to Aventis option holders regarding the
    conversion of options into options on Sanofi-Aventis ordinary
    shares (Citigroup administered plans)
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.18</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Amendment to the rules of the stock option plans
    of Aventis Inc. (formerly known as Rh&#244;ne-Poulenc Rorer Inc.)
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.19</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Amendment to the Hoechst 1999 Stock Option
    Continuity Plan
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">5</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Opinion of Patricia Kodyra regarding the validity
    of the Registrant&#146;s ordinary shares being registered
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">23.1</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Consent of PricewaterhouseCoopers Audit
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">23.2</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Consent of Ernst&nbsp;&#38; Young Audit
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">23.3</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Consent of Patricia Kodyra (included in
    Exhibit&nbsp;5 above)
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">24</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Power of Attorney
    </FONT></TD>
</TR>

</TABLE>
</CENTER>
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<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<P align="left">
<B><FONT size="2">Item&nbsp;9.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Undertakings</FONT></B>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">(a)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The undersigned
Registrant hereby undertakes:
</FONT>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">(1)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;To file, during
any period in which offers or sales are being made, a
post-effective amendment to this Registration Statement to
include any material information with respect to the plan of
distribution not previously disclosed in the Registration
Statement or any material change to such information in the
Registration Statement,
</FONT>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">(2)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;That, for the
purpose of determining any liability under the Securities Act,
each such post-effective amendment shall be deemed to be a new
registration statement relating to the securities offered
therein, and the offering of such securities at that time shall
be deemed to be the initial <I>bona fide </I>offering thereof.
</FONT>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">(3)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;To remove from
registration by means of a post-effective amendment any of the
securities being registered that remain unsold at the
termination of the offering.
</FONT>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">(b)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The undersigned
registrant hereby undertakes that, for purposes of determining
any liability under the Securities Act, each filing of the
Registrant&#146;s annual report pursuant to Section&nbsp;13(a)
or Section&nbsp;15(d) of the Exchange Act (and, where
applicable, each filing of an employee benefit plan&#146;s
annual report pursuant to Section&nbsp;15(d) of the Exchange
Act) that is incorporated by reference in the Registration
Statement shall be deemed to be the initial <I>bona fide
</I>offering thereof.
</FONT>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">(c)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Insofar as
indemnification for liabilities arising under the Securities Act
may be permitted to directors, officers, and controlling persons
of the Registrant pursuant to the provisions described in
Item&nbsp;6 of this Registration Statement, or otherwise, the
registrant has been advised that in the opinion of the
Commission such indemnification is against public policy as
expressed in the Securities Act and is, therefore,
unenforceable. In the event that a claim for indemnification
against such liabilities (other than the payment by the
Registrant of expenses incurred or paid by a director, officer,
or controlling person of the Registrant in the successful
defense of any action, suit, or proceeding) is asserted by such
director, officer, or controlling person in connection with the
securities being registered, the Registrant will, unless in the
opinion of its counsel the matter has been settled by
controlling precedent, submit to a court of appropriate
jurisdiction the question whether such indemnification by it is
against public policy as expressed in the Securities Act and
will be governed by the final adjudication of such issue.
</FONT>
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<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<P align="center">
<B>SIGNATURES</B>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">Pursuant to the requirements of the Securities
Act of 1933, the registrant has duly caused this registration
statement to be signed on its behalf by the undersigned,
thereunto duly authorized, in Paris, France, on
December&nbsp;23, 2004.
</FONT>
<P>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">

<TR>
    <TD width="36%"></TD>
    <TD width="64%"></TD>
</TR>

<TR valign="top">
    <TD>&nbsp;</TD>
    <TD align="left">
    <FONT size="2">SANOFI-AVENTIS
    </FONT></TD>
</TR>

</TABLE>
<P>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">

<TR>
    <TD width="36%"></TD>
    <TD width="2%"></TD>
    <TD width="62%"></TD>
</TR>

<TR valign="top">
    <TD>&nbsp;</TD>
    <TD><FONT size="2">By:&nbsp;</FONT></TD>
    <TD align="center">
    <FONT size="2">/s/ JEAN-FRAN&#199;OIS DEHECQ
    </FONT></TD>
</TR>

</TABLE>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">

<TR>
    <TD width="36%"></TD>
    <TD width="64%"></TD>
</TR>

<TR valign="top">
    <TD>&nbsp;</TD>
    <TD align="left">
    <HR size="1" align="left" noshade></TD>
</TR>

<TR valign="top">
    <TD>&nbsp;</TD>
    <TD align="left">
    <FONT size="2">Name:&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Jean-Fran&#231;ois
    Dehecq
    </FONT></TD>
</TR>

</TABLE>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0">

<TR>
    <TD width="36%"></TD>
    <TD width="8%"></TD>
    <TD width="56%"></TD>
</TR>

<TR valign="top">
    <TD>&nbsp;</TD>
    <TD><FONT size="2">Title:</FONT></TD>
    <TD align="left">
    <FONT size="2">Chairman&nbsp;&#38; Chief Executive Officer
    </FONT></TD>
</TR>

</TABLE>

<P align="left">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size="2">Pursuant to the requirements of the Securities
Act of 1933, as amended, this registration statement has been
signed below by the following persons in the capacities and on
the dates indicated:
</FONT>

<CENTER>
<TABLE width="100%" align="center" cellspacing="0" cellpadding="0" border="0">

<TR>
    <TD width="5%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="24%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="39%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="23%"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3"></TD>
    <TD></TD>
    <TD></TD>
    <TD></TD>
    <TD></TD>
</TR>

<TR>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Signature</FONT></B></TD>
    <TD></TD>
    <TD align="center" nowrap><B><FONT size="1">Title</FONT></B></TD>
    <TD></TD>
    <TD align="center" nowrap><B><FONT size="1">Date</FONT></B></TD>
</TR>

<TR>
    <TD colspan="3" align="center" nowrap><HR size="1" noshade></TD>
    <TD></TD>
    <TD align="center" nowrap><HR size="1" noshade></TD>
    <TD></TD>
    <TD align="center" nowrap><HR size="1" noshade></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="center" valign="top">
    <FONT size="2">/s/ JEAN-FRAN&#199;OIS DEHECQ<BR>
    <HR size="1" noshade>Jean-Fran&#231;ois Dehecq
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">Chairman, Chief Executive Officer and Director
    (Principal Executive Officer)
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">December&nbsp;23, 2004
    </FONT></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="center" valign="top">
    <FONT size="2">/s/ JEAN-CLAUDE LEROY<BR>
    <HR size="1" noshade>Jean-Claude Leroy
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">Senior Vice President and Chief Financial Officer
    (Principal Financial Officer)
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">December&nbsp;23, 2004
    </FONT></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="center" valign="top">
    <FONT size="2">/s/ JEAN-LUC RENARD<BR>
    <HR size="1" noshade>Jean-Luc Renard
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">Vice President Corporate Accounting and Tax
    (Principal Accounting Officer)
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">December&nbsp;23, 2004
    </FONT></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="center" valign="top">
    <FONT size="2">*<BR>
    <HR size="1" noshade>Ren&#233; Barbier de la Serre
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">Director
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">December&nbsp;23, 2004
    </FONT></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="center" valign="top">
    <FONT size="2">*<BR>
    <HR size="1" noshade>Jean-Marc Bruel
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">Director
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">December&nbsp;23, 2004
    </FONT></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="center" valign="top">
    <FONT size="2">*<BR>
    <HR size="1" noshade>Robert Castaigne
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">Director
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">December&nbsp;23, 2004
    </FONT></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="center" valign="top">
    <FONT size="2">*<BR>
    <HR size="1" noshade>Thierry Desmarest
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">Director
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">December&nbsp;23, 2004
    </FONT></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="center" valign="top">
    <BR>
    <HR size="1" noshade><FONT size="2">J&#252;rgen Dormann
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">Director
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="center" valign="top">
    <FONT size="2">*<BR>
    <HR size="1" noshade>Lord Douro
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">Director
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">December&nbsp;23, 2004
    </FONT></TD>
</TR>

</TABLE>
</CENTER>

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<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<CENTER>
<TABLE width="100%" align="center" cellspacing="0" cellpadding="0" border="0">

<TR>
    <TD width="5%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="24%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="39%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="23%"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3"></TD>
    <TD></TD>
    <TD></TD>
    <TD></TD>
    <TD></TD>
</TR>

<TR>
    <TD colspan="3" align="center" nowrap><B><FONT size="1">Signature</FONT></B></TD>
    <TD></TD>
    <TD align="center" nowrap><B><FONT size="1">Title</FONT></B></TD>
    <TD></TD>
    <TD align="center" nowrap><B><FONT size="1">Date</FONT></B></TD>
</TR>

<TR>
    <TD colspan="3" align="center" nowrap><HR size="1" noshade></TD>
    <TD></TD>
    <TD align="center" nowrap><HR size="1" noshade></TD>
    <TD></TD>
    <TD align="center" nowrap><HR size="1" noshade></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="center" valign="top">
    <FONT size="2">*<BR>
    <HR size="1" noshade>Jean-Ren&#233; Fourtou
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">Director
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">December&nbsp;23, 2004
    </FONT></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="center" valign="top">
    <FONT size="2">*<BR>
    <HR size="1" noshade>Serge Kampf
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">Director
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">December&nbsp;23, 2004
    </FONT></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="center" valign="top">
    <FONT size="2">*<BR>
    <HR size="1" noshade>Igor Landau
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">Director
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">December&nbsp;23, 2004
    </FONT></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="center" valign="top">
    <FONT size="2">*<BR>
    <HR size="1" noshade>Hubert Markl
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">Director
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">December&nbsp;23, 2004
    </FONT></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="center" valign="top">
    <FONT size="2">*<BR>
    <HR size="1" noshade>Christian Mulliez
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">Director
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">December&nbsp;23, 2004
    </FONT></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="center" valign="top">
    <FONT size="2">*<BR>
    <HR size="1" noshade>Lindsay Owen-Jones
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">Director
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">December&nbsp;23, 2004
    </FONT></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="center" valign="top">
    <FONT size="2">*<BR>
    <HR size="1" noshade>Klaus Pohle
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">Director
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">December&nbsp;23, 2004
    </FONT></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="center" valign="top">
    <BR>
    <HR size="1" noshade><FONT size="2">Hermann Scholl
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">Director
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="center" valign="top">
    <FONT size="2">*<BR>
    <HR size="1" noshade>G&#233;rard Van Kemmel
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">Director
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">December&nbsp;23, 2004
    </FONT></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="center" valign="top">
    <FONT size="2">*<BR>
    <HR size="1" noshade>Bruno Weymuller
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">Director
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">December&nbsp;23, 2004
    </FONT></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="center" valign="top">
    <FONT size="2">*<BR>
    <HR size="1" noshade>Timothy Rothwell
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">Authorized Representative in the United States of
    America
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">December&nbsp;23, 2004
    </FONT></TD>
</TR>

<TR>
    <TD colspan="7"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD align="center" valign="top">
    <FONT size="2">*By:
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="center" valign="top">
    <FONT size="2">/s/ JEAN-CLAUDE LEROY<BR>
    <HR size="1" noshade>Jean-Claude Leroy<BR>
    Attorney-in-fact
    </FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>

</TABLE>
</CENTER>
<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<P align="center">
<B><FONT size="2">EXHIBIT INDEX</FONT></B>

<CENTER>
<TABLE width="100%" align="center" cellspacing="0" cellpadding="0" border="0">

<TR>
    <TD width="9%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="1%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="9%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="78%"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="left" nowrap><B><FONT size="1">Exhibit&nbsp;No.</FONT></B></TD>
    <TD></TD>
    <TD align="left" nowrap><B><FONT size="1">Description</FONT></B></TD>
</TR>

<TR>
    <TD colspan="3" align="center" nowrap><HR size="1" noshade></TD>
    <TD></TD>
    <TD align="center" nowrap><HR size="1" noshade></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.1</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Bylaws (<I>statuts</I>) of Sanofi-Aventis
    (incorporated herein by reference to Exhibit&nbsp;3.1 of
    Post-Effective Amendment No.&nbsp;2 to the Registration
    Statement on Form&nbsp;F-4 (Registration No.&nbsp;333-112314) as
    filed by the Registrant with the Commission on October&nbsp;15,
    2004)
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.2</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Deposit Agreement (including the form of
    depositary receipt) between the Registrant and The Bank of New
    York, as depositary (incorporated herein by reference to
    Exhibit&nbsp;A to the Registration Statement on Form&nbsp;F-6
    (Registration No.&nbsp;333-116262) relating to American
    Depositary Shares, filed on June&nbsp;8, 2004)
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.3</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Rules and Regulations for Aventis Stock Option
    Plan 2003
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.4</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Rules and Regulations for Aventis Stock Option
    Plan 2002
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.5</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Rules and Regulations for Aventis Stock Option
    Plan 2001
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.6</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Rules and Regulations for Aventis 2000 Stock
    Option Plan
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.7</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Description of the Aventis 1999/2000 Stock Option
    Plan
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.8</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Description of the Hoechst AG&nbsp;1999 Stock
    Option Plan
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.9</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Forms of grant notice (Participation Forms) under
    the Hoechst AG&nbsp;1999 Stock Option Plan
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.10</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Hoechst 1999 Stock Option Continuity Plan
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.11</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Rh&#244;ne-Poulenc Rorer Inc. 1995 Equity
    Compensation Plan
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.12</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Rh&#244;ne-Poulenc Rorer Inc. Amended and
    Restated Stock Option Plan
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.13</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Rh&#244;ne-Poulenc S.A. 1994 Stock Option Plan
    (as authorized at the Ordinary and Extraordinary Metting of
    Shareholders held on April&nbsp;22, 1994)
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.14</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Rh&#244;ne-Poulenc S.A. 1995 Stock Option Plan
    (as authorized at the Ordinary and Extraordinary Metting of
    Shareholders held on April&nbsp;13, 1995)
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.15</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Rh&#244;ne-Poulenc S.A. 1997 Stock Option Plan
    (as authorized at the Ordinary and Extraordinary Metting of
    Shareholders held on April&nbsp;23, 1997)
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.16</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Letter to Aventis option holders regarding the
    conversion of options into options on Sanofi-Aventis ordinary
    shares (Citigroup administered plans)
    </FONT></TD>
</TR>

</TABLE>
</CENTER>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<CENTER>
<TABLE width="100%" align="center" cellspacing="0" cellpadding="0" border="0">

<TR>
    <TD width="9%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="1%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="9%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
    <TD width="78%"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="3" align="left" nowrap><B><FONT size="1">Exhibit&nbsp;No.</FONT></B></TD>
    <TD></TD>
    <TD align="left" nowrap><B><FONT size="1">Description</FONT></B></TD>
</TR>

<TR>
    <TD colspan="3" align="center" nowrap><HR size="1" noshade></TD>
    <TD></TD>
    <TD align="center" nowrap><HR size="1" noshade></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.17</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Letter to Aventis option holders regarding the
    conversion of options into options on Sanofi-Aventis ordinary
    shares (Citigroup administered plans)
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.18</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Amendment to the rules of the stock option plans
    of Aventis Inc. (formerly known as Rh&#244;ne-Poulenc Rorer Inc.)
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">4.19</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Amendment to the Hoechst 1999 Stock Option
    Continuity Plan
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">5</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Opinion of Patricia Kodyra regarding the validity
    of the Registrant&#146;s ordinary shares being registered
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">23.1</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Consent of PricewaterhouseCoopers Audit
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">23.2</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Consent of Ernst&nbsp;&#38; Young Audit
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">23.3</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Consent of Patricia Kodyra (included in
    Exhibit&nbsp;5 above)
    </FONT></TD>
</TR>

<TR>
    <TD colspan="5"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="right" valign="top" nowrap><FONT size="2">24</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD><FONT size="2">&nbsp;</FONT></TD>
    <TD align="left" valign="top">
    <FONT size="2">Power of Attorney
    </FONT></TD>
</TR>

</TABLE>
</CENTER>
</BODY>
</HTML>
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{"company-data": {"conformed-name": "SANOFI-AVENTIS", "cik": "0001121404", "assigned-sic": "2834", "irs-number": "133529324", "state-of-incorporation": "I0", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-121583", "film-number": "041223155"}, "business-address": {"street1": "174 AVENUE DE FRANCE", "city": "PARIS", "state": "I0", "zip": "75013", "phone": "33153774400"}, "mail-address": {"street1": "174 AVENUE DE FRANCE", "city": "PARIS", "state": "I0", "zip": "75013"}, "former-company": {"former-conformed-name": "SANOFI SYNTHELABO SA", "date-changed": "20010104"}}
SANOFI-AVENTIS
As Filed with the Securities and Exchange
Commission on December 23, 2004
Registration No.:
333-
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
Form S-8
Registration Statement Under The Securities Act of 1933
Sanofi-Aventis
(Exact name of Registrant as Specified in its
Charter)
Republic of France
133529324
(State or Other Jurisdiction of
Incorporation or Organization)
(I.R.S. Employer
Identification No.)
174 avenue de France
75013 Paris, France
(Address of Principal Executive
Offices and Zip Code)
Rhône-Poulenc S.A. 1994 Stock Option Plan
Rhône-Poulenc S.A. 1995 Stock Option Plan
Rhône-Poulenc S.A. 1997 Stock Option Plan
Rhône-Poulenc Rorer Inc. 1995 Equity Compensation
Plan
Rhône-Poulenc Rorer Inc. Amended and Restated Stock
Plan
Hoechst AG 1999 Stock Option Plan
1999/2000 Aventis Stock Option Plans
Aventis 2000 Stock Option Plan
Aventis Stock Option Plan 2001
Aventis Stock Option Plan 2002
Aventis Stock Option Plan 2003
(Full Titles of Plans)
Joseph Haggerty
Vice President and General Counsel
Aventis Pharmaceuticals
300 Somerset Corporate Boulevard
Bridgewater, New Jersey 08807
(Name and Address of Agent for Service)
(908) 243-6000
(Telephone Number, Including Area Code, of Agent
for Service)
Copies to:
Dirk Oldenburg
Senior Vice President and General Counsel
Sanofi-Aventis
174 avenue de France
75013, Paris, France
+ 33 1 53 77 40 00
David A. Katz
Wachtell, Lipton, Rosen & Katz
51 West 52nd Street
New York, NY 10019
(212) 403 1000
Calculation of Registration Fee
Proposed
Proposed
Maximum
Maximum
Amount
Title of Each Class of
Amount to
Offering
Aggregate
of
Securities to Be
be
Price
Offering
Registration
Registered
Registered(1)
Per Share(2)
Price(3)
Fee(4)
Sanofi-Aventis Ordinary Shares, nominal value
€
2
27,485,695
$73.17
$2,011,128,304
$236,710
(1)
In each case the number of Sanofi-Aventis
    ordinary shares registered is based on the number of Aventis
    ordinary shares subject to outstanding options that are to be
    assumed by Sanofi-Aventis in the merger after adjustment to give
    effect to the merger exchange ratio of 27 Sanofi-Aventis
    ordinary shares for 23 Aventis ordinary shares. See Explanatory
    Note.
(2)
Calculated solely for the purposes of this
    offering under Rule 457(h) of the Securities Act of 1933,
    on the basis of the weighted average exercise price of the
    outstanding options to be assumed by Sanofi-Aventis in the
    merger, in each case after adjustment to give effect to the
    merger exchange ratio of 27 Sanofi-Aventis ordinary shares for
    23 Aventis ordinary shares. See Explanatory Note. The adjusted
    exercise prices of the options have been converted into
    U.S. dollars on the basis of an exchange rate of 1 euro =
    $1.3390, which was the Federal Reserve Bank of New York noon
    buying rate on December 22, 2004.
(3)
Calculated as the product of (x) the number
    of Sanofi-Aventis ordinary shares to be registered and
    (y) the weighted average exercise price of the options
    assumed.
(4)
Calculated as the product of (x) 0.0001177
    and (y) the Proposed Maximum Aggregate Offering Price.
EXPLANATORY NOTE
On October 14, 2004, Sanofi-Aventis, a
French
société anonyme,
and Aventis, a French
société anonyme
and subsidiary of
Sanofi-Aventis in which Sanofi-Aventis holds 97.98% of the share
capital, entered into an Agreement and Plan of Merger (the
"Merger Agreement"), pursuant to which, among other
things, Aventis will merge with and into Sanofi-Aventis (the
"Merger"). As a result of the Merger, Sanofi-Aventis
will continue as the surviving company, Aventis will be
dissolved and the shareholders of Aventis (other than Aventis
and Sanofi-Aventis) will receive 27 Sanofi-Aventis ordinary
shares, nominal value
€
2 per
share, for every 23 Aventis ordinary shares, nominal value
€
3.82 per
share, that they hold (such ratio, the "Merger Exchange
Ratio"). For legal purposes, the Merger Agreement provides
that the Merger will be effective as of December 31, 2004.
On December 13, 2004, at a combined ordinary
and extraordinary general meeting, the shareholders of Aventis
voted to approve the Merger Agreement, the Merger and the
dissolution of Aventis. On December 23, 2004, at an
extraordinary general meeting, the shareholders of
Sanofi-Aventis voted to approve the Merger Agreement and the
Merger, as well as the increase in the share capital of
Sanofi-Aventis and the issuance of the new Sanofi-Aventis
ordinary shares to be issued in payment of the merger
consideration.
The Merger Agreement expressly provides that
Sanofi-Aventis, as successor to Aventis, agrees to be bound by
Aventis's obligations under the Aventis subscription stock
options. After the effective time of the Merger, the Aventis
subscription stock options will entitle their holders to
subscribe for Sanofi-Aventis ordinary shares instead of Aventis
ordinary shares. The number of shares subject to the options and
their exercise price will be adjusted to give effect to the
Merger Exchange Ratio in the following manner:
•
the number of Sanofi-Aventis ordinary shares that
    each holder of Sanofi-Aventis options shall have the right to
    subscribe under any given subscription option plan shall equal
    that number of Aventis ordinary shares that could formerly have
    been subscribed under that plan multiplied by the Merger
    Exchange Ratio of 27/23 (or approximately 1.17391) applicable to
    shareholders, rounded down to the nearest whole number; and
•
the exercise price per Sanofi-Aventis ordinary
    share shall be equal to the exercise price per Aventis ordinary
    share divided by the Merger Exchange Ratio of 27/23 (or
    approximately 1.17391) applicable to shareholders, rounded down
    to the nearest whole euro centime;
with all other terms of exercise remaining
unaltered.
At the extraordinary general meeting on
December 31, 2004, Sanofi-Aventis shareholders voted to
waive their preferential subscription rights with respect to the
Sanofi-Aventis ordinary shares that will be issued on the
exercise of the Aventis subscription stock options assumed by
Sanofi-Aventis.
With respect to the purchase option plans issued
by Aventis Inc. (formerly known as Rhône-Poulenc Rorer,
Inc.) and Hoechst which provide for the purchase of Aventis
shares, the Merger Agreement provides that Sanofi-Aventis shall
cause the regulations of these plans to be amended to provide
that, after the effective time of the Merger, holders of these
purchase options may purchase Sanofi-Aventis shares after
adjusting the purchase price and the number of shares subject to
option by the Merger Exchange Ratio in the same manner as set
forth above, with all other terms of exercise remaining
unaltered.
Accordingly, this Registration Statement on
Form S-8 registers the aggregate number of Sanofi-Aventis
ordinary shares that may be issued on the exercise of
outstanding Aventis subscription stock options held by U.S
holders. The following table sets forth (i) the date of the
grant, (ii) the number of unexercised subscription stock
options held by U.S. holders, (iii) the original
exercise price of the options, (iv) the number of
Sanofi-Aventis ordinary shares for which the options may be
exercised after the Merger and which are being registered
pursuant to this Registration Statement and (v) the
adjusted exercise price:
Number of Sanofi-
Aventis ordinary shares
to be issued on
exercise
Number of Aventis
of options after the
ordinary shares subject
Merger and registered
to outstanding options
pursuant to this
Date of Original Grant
held by U.S. holders
Original Exercise Price
Registration Statement
Adjusted Exercise Price
February 7, 1995
8,500
€
17.66
9,978
€
15.04
December 14, 1995
10,000
€
15.40
11,739
€
13.11
December 17, 1996
17,500
€
23.53
20,543
€
20.04
December 16, 1997
291,647
€
37.75
342,368
€
32.15
December 15, 1998
639,433
€
40.08
750,639
€
34.14
February 15, 1999
1,340,575
€
58.75
1,573,718
€
50.04
May 11, 2000
240,520
€
58.29
282,350
€
49.65
November 14, 2000
4,573,466
€
79.75
5,368,851
€
67.93
March 29, 2001
53,250
€
80.94
62,511
€
68.94
November 7, 2001
4,659,375
€
83.81
5,469,701
€
71.39
November 12, 2002
5,160,200
€
60.27
6,057,626
€
51.34
December 2, 2003
6,006,955
€
47.52
7,051,643
€
40.48
Total/ wt. average
23,001,421
€
64.61
27,001,668
€
55.04
This Registration Statement also registers the
aggregate number of Sanofi-Aventis ordinary shares that may be
purchased on the exercise of outstanding purchase stock options
held by U.S. holders issued under the option plans of Aventis
Inc. (formerly known as Rhône-Poulenc Rorer Inc.). The
following table sets forth the same data as above with respect
to these purchase options:
Number of Sanofi-
Aventis ordinary shares
to be issued on
exercise
Number of Aventis
of options after the
ordinary shares subject
Merger and registered
to outstanding options
pursuant to this
Date of Original Grant
held by U.S. holders
Original Exercise Price
Registration Statement
Adjusted Exercise Price
February 27, 1995
30,017
$
16.67
35,237
$
14.20
February 27, 1996
44,554
$
26.67
52,303
$
22.71
February 20, 1997
64,546
$
30.68
75,771
$
26.13
Total/wt average
139,117
$
26.37
163,311
$
22.46
This Registration Statement also registers the
aggregate number of Sanofi-Aventis ordinary shares that may be
purchased on the exercise of outstanding purchase stock options
held by U.S. holders issued under the option plans of Hoechst.
The following table sets forth the same data as above with
respect to these purchase options:
Number of Sanofi-
Aventis ordinary shares
to be issued on
exercise
Number of Aventis
of options after the
ordinary shares subject
Merger and registered
to outstanding options
pursuant to this
Date of Original Grant
held by U.S. holders
Original Exercise Price
Registration Statement
Adjusted Exercise Price
September 7, 1999
273,202
€
48.43
320,715
€
41.25
PART I
INFORMATION REQUIRED IN THE
PROSPECTUS
Item 1.
Plan Information
Omitted pursuant to the instructions and
provisions of Form S-8.
Item 2.
Registrant Information and Employee Plan
    Annual Information
Omitted pursuant to the instructions and
provisions of Form S-8.
PART II
INFORMATION REQUIRED IN THE REGISTRATION
STATEMENT
Item 3.
Incorporation of Documents by
    Reference
This Registration Statement on Form S-8
hereby incorporates by reference the contents of the following
reports of Sanofi-Aventis (the "Registrant", formerly
known as Sanofi-Synthélabo) filed with, or furnished to,
the Securities and Exchange Commission (the
"Commission") pursuant to the Securities Exchange Act
of 1934, as amended (the "Exchange Act"):
(a)     The Annual
Report on Form 20-F of the Registrant for the year ended
December 31, 2003 (the "Form 20-F")
(Commission file No. 001-31368);
(b)     The Reports on
Form 6-K furnished by the Registrant (whether under the
names Sanofi-Synthélabo or Sanofi-Aventis) to the
Commission pursuant to Section 13(a) or 15(d) of the
Exchange Act on the following dates: January 7, 2004,
January 8, 2004, January 12, 2004, January 20,
2004, January 29, 2004, February 4, 2004,
February 16, 2004, March 9, 2004, March 10, 2004,
March 19, 2004, March 23, 2004, March 31, 2004,
April 5, 2004, April 12, 2004, April 13, 2004,
April 15, 2004, April 22, 2004, April 26, 2004,
April 27, 2004, May 4, 2004, May 5, 2004,
May 14, 2004, May 21, 2004, May 26, 2004,
June 2, 2004, June  4, 2004, June 14, 2004,
June 22, 2004, June 24, 2004, June 25, 2004,
July 15, 2004 (two reports), July 21, 2004,
July 29, 2004, August 2, 2004, August 9, 2004,
August 12, 2004, August 13, 2004, August 19,
2004, August 24, 2004, August 31, 2004,
September 7, 2004, September 14, 2004,
September 16, 2004, September 17, 2004, September 22
(two reports), October 8, 2004 (report relating to
Actonel® press release), October 14, 2004,
November 5, 2004 (report relating to Taxotere® and
Eloxatin® press releases); November 9, 2004;
November 24, 2004, November 26, 2004 (report relating
to press release regarding relocation of Aventis headquarters),
November 30, 2004, December 9, 2004 (report relating
to press release regarding U.S. intellectual property
litigation); December 10, 2004; December 16, 2004
(report relating to financial calendar of Sanofi-Aventis);
December 20, 2004; December 22, 2004 and
December 23, 2004;
(c)     The description
of the Registrant's ordinary shares, nominal
value
€
2 per
share, set forth under the captions "A. Share Capital"
and "B. Memorandum and Articles of Association" in
Item 10 of the Registrant's Registration Statement on
Form 20-F (Commission file No. 001-31368), filed with
the Commission on June 25, 2002 and the updated
descriptions of the Registrant's ordinary shares and
American depositary shares contained in the Post-Effective
Amendment No. 3 to the Registration Statement on
Form F-4 (Registration No. 333-112314) (the
"Form F-4") filed by the Registrant with the
Commission on November 9, 2004, under the captions
"Description Of Sanofi-Aventis Ordinary Shares" and
"Description Of Sanofi-Aventis American Depositary
Shares", including any amendment or report filed for the
purpose of updating such description; and
(d)     All documents
filed by the Registrant with the Commission pursuant to
Sections 13(a), 13(c), 14, or 15(d) of the Exchange
Act prior to the filing of a post-effective amendment indicating
that all securities offered have been sold or that deregisters
all securities then remaining unsold shall be deemed to be
incorporated by reference in this Registration Statement and to
be a part hereof from the date of filing of such documents
reference. Statements contained in the foregoing documents
incorporated by reference shall be deemed to be modified or
superseded hereby to the extent that statements contained in the
Prospectus, or in any subsequently filed documents that are
amendments hereto or that are incorporated herein by reference,
shall modify or replace such statements.
Item 4.
Description of Securities
The information required by Item 4 is not
applicable to this Registration Statement because the class of
securities to be offered is registered under Section 12 of
the Exchange Act.
Item 5.
Interests of named Experts and
    Counsel
The information required by Item 5 is not
applicable to this Registration Statement.
Item 6.
Indemnification of Directors and
    Officers
The French Commercial Code prohibits provisions
of
statuts
that limit the liability of directors.
However, if a director is sued by a third party and ultimately
prevails in the litigation on all counts, but is nevertheless
required to bear attorneys' fees and costs, the company may
reimburse those fees and costs pursuant to an indemnification
arrangement with the director.
Under French law a company may purchase directors
and officers' insurance for all or part of the members of
its management. A French corporation is responsible to third
parties for the consequences of the decisions of its board of
directors. However, if those decisions qualify as mismanagement,
the relevant member of the board of directors may have to fully
or partly indemnify the company. Sanofi-Aventis has purchased
insurance for all of its directors.
Item 7.
Exemption from Registration Claimed
The information required by Item 7 is not
applicable to this Registration Statement.
Item 8.
Exhibits
4.1
Bylaws (
statuts
) of Sanofi-Aventis
    (incorporated herein by reference to Exhibit 3.1 of
    Post-Effective Amendment No. 2 to the Registration
    Statement on Form F-4 (Registration No. 333-112314) as
    filed by the Registrant with the Commission on October 15,
    2004)
4.2
Deposit Agreement (including the form of
    depositary receipt) between the Registrant and The Bank of New
    York, as depositary (incorporated herein by reference to
    Exhibit A to the Registration Statement on Form F-6
    (Registration No. 333-116262) relating to American
    Depositary Shares, filed on June 8, 2004)
4.3
Rules and Regulations for Aventis Stock Option
    Plan 2003
4.4
Rules and Regulations for Aventis Stock Option
    Plan 2002
4.5
Rules and Regulations for Aventis Stock Option
    Plan 2001
4.6
Rules and Regulations for Aventis 2000 Stock
    Option Plan
4.7
Description of the Aventis 1999/2000 Stock Option
    Plan
4.8
Description of the Hoechst AG 1999 Stock
    Option Plan
4.9
Forms of grant notice (Participation Forms) under
    the Hoechst AG 1999 Stock Option Plan
4.10
Hoechst 1999 Stock Option Continuity Plan
4.11
Rhône-Poulenc Rorer Inc. 1995 Equity
    Compensation Plan
4.12
Rhône-Poulenc Rorer Inc. Amended and
    Restated Stock Option Plan
4.13
Rhône-Poulenc S.A. 1994 Stock Option Plan
    (as authorized at the Ordinary and Extraordinary Metting of
    Shareholders held on April 22, 1994)
4.14
Rhône-Poulenc S.A. 1995 Stock Option Plan
    (as authorized at the Ordinary and Extraordinary Metting of
    Shareholders held on April 13, 1995)
4.15
Rhône-Poulenc S.A. 1997 Stock Option Plan
    (as authorized at the Ordinary and Extraordinary Metting of
    Shareholders held on April 23, 1997)
4.16
Letter to Aventis option holders regarding the
    conversion of options into options on Sanofi-Aventis ordinary
    shares (Citigroup administered plans)
4.17
Letter to Aventis option holders regarding the
    conversion of options into options on Sanofi-Aventis ordinary
    shares (Citigroup administered plans)
4.18
Amendment to the rules of the stock option plans
    of Aventis Inc. (formerly known as Rhône-Poulenc Rorer Inc.)
4.19
Amendment to the Hoechst 1999 Stock Option
    Continuity Plan
5
Opinion of Patricia Kodyra regarding the validity
    of the Registrant's ordinary shares being registered
23.1
Consent of PricewaterhouseCoopers Audit
23.2
Consent of Ernst & Young Audit
23.3
Consent of Patricia Kodyra (included in
    Exhibit 5 above)
24
Power of Attorney
Item 9.     Undertakings
(a)     The undersigned
Registrant hereby undertakes:
(1)     To file, during
any period in which offers or sales are being made, a
post-effective amendment to this Registration Statement to
include any material information with respect to the plan of
distribution not previously disclosed in the Registration
Statement or any material change to such information in the
Registration Statement,
(2)     That, for the
purpose of determining any liability under the Securities Act,
each such post-effective amendment shall be deemed to be a new
registration statement relating to the securities offered
therein, and the offering of such securities at that time shall
be deemed to be the initial
bona fide
offering thereof.
(3)     To remove from
registration by means of a post-effective amendment any of the
securities being registered that remain unsold at the
termination of the offering.
(b)     The undersigned
registrant hereby undertakes that, for purposes of determining
any liability under the Securities Act, each filing of the
Registrant's annual report pursuant to Section 13(a)
or Section 15(d) of the Exchange Act (and, where
applicable, each filing of an employee benefit plan's
annual report pursuant to Section 15(d) of the Exchange
Act) that is incorporated by reference in the Registration
Statement shall be deemed to be the initial
bona fide
offering thereof.
(c)     Insofar as
indemnification for liabilities arising under the Securities Act
may be permitted to directors, officers, and controlling persons
of the Registrant pursuant to the provisions described in
Item 6 of this Registration Statement, or otherwise, the
registrant has been advised that in the opinion of the
Commission such indemnification is against public policy as
expressed in the Securities Act and is, therefore,
unenforceable. In the event that a claim for indemnification
against such liabilities (other than the payment by the
Registrant of expenses incurred or paid by a director, officer,
or controlling person of the Registrant in the successful
defense of any action, suit, or proceeding) is asserted by such
director, officer, or controlling person in connection with the
securities being registered, the Registrant will, unless in the
opinion of its counsel the matter has been settled by
controlling precedent, submit to a court of appropriate
jurisdiction the question whether such indemnification by it is
against public policy as expressed in the Securities Act and
will be governed by the final adjudication of such issue.
SIGNATURES
Pursuant to the requirements of the Securities
Act of 1933, the registrant has duly caused this registration
statement to be signed on its behalf by the undersigned,
thereunto duly authorized, in Paris, France, on
December 23, 2004.
SANOFI-AVENTIS
By:
/s/ JEAN-FRANÇOIS DEHECQ
Name:        Jean-François
    Dehecq
Title:
Chairman & Chief Executive Officer
Pursuant to the requirements of the Securities
Act of 1933, as amended, this registration statement has been
signed below by the following persons in the capacities and on
the dates indicated:
Signature
Title
Date
/s/ JEAN-FRANÇOIS DEHECQ
Jean-François Dehecq
Chairman, Chief Executive Officer and Director
    (Principal Executive Officer)
December 23, 2004
/s/ JEAN-CLAUDE LEROY
Jean-Claude Leroy
Senior Vice President and Chief Financial Officer
    (Principal Financial Officer)
December 23, 2004
/s/ JEAN-LUC RENARD
Jean-Luc Renard
Vice President Corporate Accounting and Tax
    (Principal Accounting Officer)
December 23, 2004
*
René Barbier de la Serre
Director
December 23, 2004
*
Jean-Marc Bruel
Director
December 23, 2004
*
Robert Castaigne
Director
December 23, 2004
*
Thierry Desmarest
Director
December 23, 2004
Jürgen Dormann
Director
*
Lord Douro
Director
December 23, 2004
Signature
Title
Date
*
Jean-René Fourtou
Director
December 23, 2004
*
Serge Kampf
Director
December 23, 2004
*
Igor Landau
Director
December 23, 2004
*
Hubert Markl
Director
December 23, 2004
*
Christian Mulliez
Director
December 23, 2004
*
Lindsay Owen-Jones
Director
December 23, 2004
*
Klaus Pohle
Director
December 23, 2004
Hermann Scholl
Director
*
Gérard Van Kemmel
Director
December 23, 2004
*
Bruno Weymuller
Director
December 23, 2004
*
Timothy Rothwell
Authorized Representative in the United States of
    America
December 23, 2004
*By:
/s/ JEAN-CLAUDE LEROY
Jean-Claude Leroy
Attorney-in-fact
EXHIBIT INDEX
Exhibit No.
Description
4.1
Bylaws (
statuts
) of Sanofi-Aventis
    (incorporated herein by reference to Exhibit 3.1 of
    Post-Effective Amendment No. 2 to the Registration
    Statement on Form F-4 (Registration No. 333-112314) as
    filed by the Registrant with the Commission on October 15,
    2004)
4.2
Deposit Agreement (including the form of
    depositary receipt) between the Registrant and The Bank of New
    York, as depositary (incorporated herein by reference to
    Exhibit A to the Registration Statement on Form F-6
    (Registration No. 333-116262) relating to American
    Depositary Shares, filed on June 8, 2004)
4.3
Rules and Regulations for Aventis Stock Option
    Plan 2003
4.4
Rules and Regulations for Aventis Stock Option
    Plan 2002
4.5
Rules and Regulations for Aventis Stock Option
    Plan 2001
4.6
Rules and Regulations for Aventis 2000 Stock
    Option Plan
4.7
Description of the Aventis 1999/2000 Stock Option
    Plan
4.8
Description of the Hoechst AG 1999 Stock
    Option Plan
4.9
Forms of grant notice (Participation Forms) under
    the Hoechst AG 1999 Stock Option Plan
4.10
Hoechst 1999 Stock Option Continuity Plan
4.11
Rhône-Poulenc Rorer Inc. 1995 Equity
    Compensation Plan
4.12
Rhône-Poulenc Rorer Inc. Amended and
    Restated Stock Option Plan
4.13
Rhône-Poulenc S.A. 1994 Stock Option Plan
    (as authorized at the Ordinary and Extraordinary Metting of
    Shareholders held on April 22, 1994)
4.14
Rhône-Poulenc S.A. 1995 Stock Option Plan
    (as authorized at the Ordinary and Extraordinary Metting of
    Shareholders held on April 13, 1995)
4.15
Rhône-Poulenc S.A. 1997 Stock Option Plan
    (as authorized at the Ordinary and Extraordinary Metting of
    Shareholders held on April 23, 1997)
4.16
Letter to Aventis option holders regarding the
    conversion of options into options on Sanofi-Aventis ordinary
    shares (Citigroup administered plans)
Exhibit No.
Description
4.17
Letter to Aventis option holders regarding the
    conversion of options into options on Sanofi-Aventis ordinary
    shares (Citigroup administered plans)
4.18
Amendment to the rules of the stock option plans
    of Aventis Inc. (formerly known as Rhône-Poulenc Rorer Inc.)
4.19
Amendment to the Hoechst 1999 Stock Option
    Continuity Plan
5
Opinion of Patricia Kodyra regarding the validity
    of the Registrant's ordinary shares being registered
23.1
Consent of PricewaterhouseCoopers Audit
23.2
Consent of Ernst & Young Audit
23.3
Consent of Patricia Kodyra (included in
    Exhibit 5 above)
24
Power of Attorney