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<TITLE>Form S-8</TITLE>
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<DIV align="center" style="font-size: 10pt; margin-top: 1pt"><B>As Filed with the Securities and Exchange Commission on June&nbsp;16, 2011</B>
</DIV>


<DIV align="right" style="font-size: 10pt; margin-top: 7pt"><B>Registration No.&nbsp;333-</B>
</DIV>

<DIV align="right" style="font-size: 1pt; margin-top: 3pt">&nbsp;
</DIV>

<DIV style="width: 100%; border-bottom: 2pt solid black; font-size: 1pt">&nbsp;</DIV>
<DIV style="width: 100%; border-bottom: 1pt solid black; font-size: 1pt">&nbsp;</DIV>




<DIV align="center" style="font-size: 14pt; margin-top: 7pt"><B>UNITED STATES<BR>
SECURITIES AND EXCHANGE COMMISSION</B>
</DIV>

<DIV align="center" style="font-size: 12pt"><B>Washington, D.C. 20549</B>
</DIV>

<DIV align="center" style="font-size: 12pt"><B><DIV align="center"><DIV style="FONT-size: 3pt; margin-top: 13pt; width: 26%; border-top: 1px solid #000000">&nbsp;</DIV></DIV></B>
</DIV>

<DIV align="center" style="font-size: 18pt; margin-top: 7pt"><B>FORM S-8</B>
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 0pt"><B>REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933</B>
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 7pt"><DIV align="center"><DIV style="FONT-size: 3pt; margin-top: 13pt; width: 26%; border-top: 1px solid #000000">&nbsp;</DIV></DIV>
</DIV>

<DIV align="center" style="font-size: 24pt; margin-top: 7pt"><B>ADVENTRX Pharmaceuticals, Inc.</B>
</DIV>

<DIV align="center" style="font-size: 10pt">
(Exact name of registrant as specified in its charter)</DIV>

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
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    <TD width="47%">&nbsp;</TD>
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    <TD width="47%">&nbsp;</TD>
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<TR valign="bottom">
    <TD align="center" valign="top"><B>Delaware</B><BR>
(State or other jurisdiction of <BR>
incorporation or organization)
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top"><B>84-1318182</B><BR>
(I.R.S. Employer<BR>
Identification No.)</TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD align="center" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD align="center" valign="top"><B>12390 El Camino Real, Suite&nbsp;150</B></TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD align="center" valign="top"><B>San Diego, California</B>
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top"><B>92130</B></TD>
</TR>
<TR valign="bottom">
    <TD align="center" valign="top">(Address of Principal Executive Offices)
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">(Zip Code)</TD>
</TR>
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</TABLE>
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 7pt"><DIV align="center"><DIV style="FONT-size: 3pt; margin-top: 13pt; width: 26%; border-top: 1px solid #000000">&nbsp;</DIV></DIV>
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 7pt"><B>ADVENTRX Pharmaceuticals, Inc. Amended and Restated 2008 Omnibus Incentive Plan</B>
</DIV>


<DIV align="Center" style="font-size: 10pt; margin-top: 7pt">(Full title of the plans)
</DIV>

<DIV align="Center" style="font-size: 10pt; margin-top: 7pt"><DIV align="center"><DIV style="FONT-size: 3pt; margin-top: 13pt; width: 26%; border-top: 1px solid #000000">&nbsp;</DIV></DIV>
</DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 7pt"><B>Brian M. Culley<BR>
Chief Executive Officer<BR>
ADVENTRX Pharmaceuticals, Inc.<BR>
12390 El Camino Real, Suite&nbsp;150<BR>
San Diego, California, 92130</B><BR>
(Name and Address of Agent For Service)
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 7pt"><B>(858)&nbsp;552-0866</B><BR>
(Telephone number, including area code, of agent for service)
</DIV>


<DIV align="Center" style="font-size: 10pt; margin-top: 7pt"><B><I>Copies to:</I></B>
</DIV>
<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
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<TR valign="bottom">
    <TD width="47%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="47%">&nbsp;</TD>
</TR>
<TR></TR>
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<TR valign="bottom">
    <TD align="center" valign="top"><B>Patrick L. Keran</B></TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top"><B>Kirt W. Shuldberg, Esq.</B></TD>
</TR>
<TR valign="bottom">
    <TD align="center" valign="top"><B>President and Chief Operating Officer and</B></TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top"><B>Sheppard, Mullin, Richter
&#038; Hampton LLP</B></TD>
</TR>
<TR valign="bottom">
    <TD align="center" valign="top"><B>Principal Financial Officer</B>
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top"><B>12275 El Camino Real,
Suite&nbsp;200</B></TD>
</TR>
<TR valign="bottom">
    <TD align="center" valign="top"><B>ADVENTRX Pharmaceuticals, Inc.</B>
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top"><B>San Diego, CA 92130</B></TD>
</TR>
<TR valign="bottom">
    <TD align="center" valign="top"><B>12390 El Camino Real, Suite&nbsp;150</B>
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top"><B>(858)&nbsp;720-8900</B></TD>
</TR>
<TR valign="bottom">
    <TD align="center" valign="top"><B>San Diego, California, 92130</B>
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD align="center" valign="top"><B>(858)&nbsp;552-0866</B>
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">&nbsp;</TD>
</TR>
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</TABLE>
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 7pt"><DIV align="center"><DIV style="FONT-size: 3pt; margin-top: 13pt; width: 26%; border-top: 1px solid #000000">&nbsp;</DIV></DIV>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 7pt">Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a
non-accelerated filer, or a smaller reporting company. See the definitions of &#147;large accelerated
filer,&#148; &#147;accelerated filer,&#148; and &#147;smaller reporting company&#148; in Rule&nbsp;12b-2 of the Exchange Act.
(Check one):
</DIV>

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
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<TR valign="bottom">
    <TD width="22%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="22%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="22%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="22%">&nbsp;</TD>
</TR>
<TR></TR>
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<TR valign="bottom">
    <TD align="center" valign="top">Large Accelerated filer <FONT style="font-family: Wingdings">&#111;</FONT>
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">Accelerated filer <FONT style="font-family: Wingdings">&#111;</FONT>
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top"><font style="white-space: nowrap">Non-accelerated filer <FONT style="font-family: Wingdings">&#111;</FONT><br>
(Do not check if a smaller reporting company)</font>
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top"><font style="white-space: nowrap">Smaller reporting company <FONT style="font-family: Wingdings">&#254;</FONT></font></TD>
</TR>
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</TABLE>
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 7pt"><B>CALCULATION OF REGISTRATION FEE</B>
</DIV>

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="1%">&nbsp;</TD>
    <TD width="46%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD><!-- VRule -->
    <TD width="1%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD><!-- VRule -->
    <TD width="1%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD><!-- VRule -->
    <TD width="1%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD><!-- VRule -->
    <TD width="1%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>

    <TD width="1%">&nbsp;</TD>
</TR><TR style="font-size: 1px" valign="bottom">
    <TD nowrap align="left" colspan="23" style="border-bottom: 3px double #000000">&nbsp;</TD>
</TR>
<TR style="font-size: 10pt" valign="bottom">    <TD width="1%">&nbsp;</TD>

    <TD>&nbsp;</TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Proposed</B></TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3">&nbsp;</TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
</TR>
<TR style="font-size: 10pt" valign="bottom">    <TD width="1%">&nbsp;</TD>

    <TD>&nbsp;</TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Maximum</B></TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Proposed Maximum</B></TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
</TR>
<TR style="font-size: 10pt" valign="bottom">    <TD width="1%">&nbsp;</TD>

    <TD>&nbsp;</TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Amount to be</B></TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Offering Price</B></TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Aggregate Offering</B></TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Amount of</B></TD>
    <TD width="1%">&nbsp;</TD>
</TR>
<TR style="font-size: 10pt" valign="bottom">    <TD width="1%">&nbsp;</TD>

    <TD nowrap align="left"><B>Title of Securities to be Registered</B></TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Registered (1)</B></TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Per Share</B></TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Price</B></TD>
    <TD style="border-right: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3"><B>Registration Fee</B></TD>
    <TD width="1%">&nbsp;</TD>
</TR>

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<TR valign="bottom">
    <TD width="1%" style="border-top: 1px solid #000000">&nbsp;</TD>
                    <TD style="border-top: 1px solid #000000"><DIV style="margin-left:15px; text-indent:-15px">Common Stock, par value $0.001 per
share: To be issued under the ADVENTRX
Pharmaceuticals, Inc. Amended and
Restated 2008 Omnibus Incentive Plan (2)</DIV></TD>
    <TD style="border-right: 1px solid #000000; border-top: 1px solid #000000">&nbsp;</TD>
    <TD style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD colspan="3" align="right" style="border-top: 1px solid #000000" nowrap>3,637,415 shares</TD>
    <TD style="border-right: 1px solid #000000; border-top: 1px solid #000000">&nbsp;</TD>
    <TD style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD nowrap align="right" style="border-top: 1px solid #000000">$</TD>
    <TD align="right" style="border-top: 1px solid #000000">2.35</TD>
    <TD nowrap style="border-top: 1px solid #000000">(3)</TD>
    <TD style="border-right: 1px solid #000000; border-top: 1px solid #000000">&nbsp;</TD>
    <TD style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD nowrap align="right" style="border-top: 1px solid #000000">$</TD>
    <TD align="right" style="border-top: 1px solid #000000">8,547,925      </TD>
    <TD nowrap style="border-top: 1px solid #000000">(3)</TD>
    <TD style="border-right: 1px solid #000000; border-top: 1px solid #000000">&nbsp;</TD>
    <TD style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD align="right" style="border-top: 1px solid #000000">$</TD>
    <TD align="right" style="border-top: 1px solid #000000">992.41</TD>
    <TD style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD width="1%" style="border-top: 1px solid #000000">&nbsp;</TD>
</TR>
<TR style="font-size: 1px" valign="bottom">
    <TD nowrap align="left" colspan="23" style="border-top: 3px double #000000">&nbsp;</TD>
</TR>

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</TABLE>
</DIV>



<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
<TR style="font-size: 6pt">
    <TD width="3%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="96%">&nbsp;</TD>
</TR>

<TR valign="top">
    <TD nowrap align="left">(1)</TD>
    <TD>&nbsp;</TD>
    <TD>Pursuant to Rule&nbsp;416 under the Securities Act of 1933,
as amended (the &#147;Securities Act&#148;), this Registration
Statement shall also cover any additional shares of common
stock which become issuable under the ADVENTRX
Pharmaceuticals, Inc. Amended and Restated 2008 Omnibus
Incentive Plan (the &#147;2008 Plan&#148;), by reason of any stock
split, stock dividend, recapitalization or any other similar
transaction, effected without receipt of consideration,
which results in an increase in the Registrant&#146;s outstanding
shares of common stock.</TD>
</TR>

<TR style="font-size: 3pt"><TD>&nbsp;</TD></TR>

<TR valign="top">
    <TD nowrap align="left">(2)</TD>
    <TD>&nbsp;</TD>
    <TD>Represents 3,637,415 additional shares of the
Registrant&#146;s common stock that became available for issuance
on June&nbsp;15, 2011 under the 2008 Plan, which shares are in
addition to the 523,900 shares of common stock (on a
post-April&nbsp;23, 2010 reverse stock split basis) registered on
the Registrant&#146;s Form S-8 filed with the Securities and
Exchange Commission (the &#147;SEC&#148;) on June&nbsp;25, 2008 (Commission
File No.&nbsp;333-151903).</TD>
</TR>

<TR style="font-size: 3pt"><TD>&nbsp;</TD></TR>

<TR valign="top">
    <TD nowrap align="left">(3)</TD>
    <TD>&nbsp;</TD>
    <TD>Estimated pursuant to Rules 457(c) and 457(h) under the
Securities Act solely for the purpose of calculating the
registration fee, based on the average of the high and low
prices of the Registrant&#146;s common stock as reported on the
NYSE Amex Equities on June&nbsp;13, 2011.</TD>
</TR>

</TABLE>



<DIV align="left" style="font-size: 10pt; margin-top: 7pt">The Registration Statement shall become effective upon filing in accordance with Rule 462(a)
under the Securities Act.
</DIV>

<DIV style="width: 100%; border-bottom: 1pt solid black; margin-top: 7pt; font-size: 1pt">&nbsp;</DIV>
<DIV style="width: 100%; border-bottom: 2pt solid black; font-size: 1pt">&nbsp;</DIV>






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<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: 'Times New Roman',Times,serif; margin-left: .25in; width: 7.50in">




<DIV align="center" style="font-size: 10pt; margin-top: 10pt"><B>PART I</B>
</DIV>


<DIV align="Center" style="font-size: 10pt; margin-top: 10pt"><B>INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS</B>
</DIV>

<DIV align="left" style="margin-top: 10pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt; background: transparent; color: #000000">
<TR>
    <TD width="7%"></TD>
    <TD width="1%"></TD>
    <TD></TD>
</TR>
<TR valign="top">
    <TD nowrap align="left"><B>Item&nbsp;1.</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Plan Information.*</B></TD>
</TR>
</TABLE>
</DIV>

<DIV align="left" style="margin-top: 10pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt; background: transparent; color: #000000">
<TR>
    <TD width="7%"></TD>
    <TD width="1%"></TD>
    <TD></TD>
</TR>
<TR valign="top">
    <TD nowrap align="left"><B>Item&nbsp;2.</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Registrant Information and Employee Program Annual Information.*</B></TD>
</TR>
</TABLE>
</DIV>


<DIV style="margin-top: 10pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="3%" nowrap align="left">*</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Information required by Part&nbsp;I to be contained in the Section 10(a) prospectus is omitted from
this Registration Statement in accordance with Rule&nbsp;428 under the Securities Act and the Note to
Part&nbsp;I of Form S-8.</TD>
</TR>

</TABLE>
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 10pt"><B>PART II</B>
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 10pt"><B>INFORMATION REQUIRED IN REGISTRATION STATEMENT</B>
</DIV>


<DIV align="left" style="margin-top: 10pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt; background: transparent; color: #000000">
<TR>
    <TD width="7%"></TD>
    <TD width="1%"></TD>
    <TD></TD>
</TR>
<TR valign="top">
    <TD nowrap align="left"><B>Item&nbsp;3.</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Incorporation of Documents by Reference.</B></TD>
</TR>
</TABLE>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">The SEC allows the Registrant to &#147;incorporate by reference&#148; the information that the
Registrant files with them, which means that the Registrant can disclose important information by
reference to those documents. The information incorporated by reference is considered to be part
of this Registration Statement, and later information filed with the SEC will update and supersede
this information. The following documents filed by the Registrant with the SEC are hereby
incorporated by reference into this Registration Statement:
</DIV>

<DIV style="margin-top: 10pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(a)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The Registrant&#146;s Annual Report on Form 10-K for the fiscal year ended December
31, 2010, filed with the SEC on March&nbsp;10, 2011, including all material incorporated by
reference therein;</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 10pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(b)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The Registrant&#146;s Quarterly Report on Form 10-Q for the quarter ended March&nbsp;31,
2011, filed with the SEC on May&nbsp;9, 2011, including all material incorporated by
reference therein;</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 10pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(c)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The Registrant&#146;s Current Reports on Form 8-K filed on March&nbsp;10, 2011, March&nbsp;22,
2011, April&nbsp;11, 2011 and May&nbsp;9, 2011, including all material incorporated by reference
therein; and</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 10pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(d)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The description of the Registrant&#146;s common stock contained in the Registrant&#146;s
Registration Statement on Form 8-A (File No.&nbsp;001-32157) filed with the SEC on April
27, 2004, pursuant to Section 12(b) of the Securities Exchange Act of 1934, as amended
(the &#147;Exchange Act&#148;), including any amendments or reports filed for the purpose of
updating such descriptions.</TD>
</TR>

</TABLE>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">In addition, all documents subsequently filed by the Registrant pursuant to Sections&nbsp;13(a),
13(c), 14 and 15(d) of the Exchange Act, after the date of this Registration Statement and prior to
the filing of a post-effective amendment which indicates that all securities offered have been sold
or which deregisters all securities then remaining unsold, will be incorporated by reference into
this Registration Statement from the date of filing of such documents.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">Any statement contained in a document incorporated or deemed to be incorporated by reference
herein shall be deemed to be modified or superseded for the purposes of this Registration Statement
to the extent that a statement contained herein or in any other subsequently filed document which
also is or deemed to be incorporated by reference herein modifies or supersedes such statement. Any
statement so modified or superseded shall not be deemed, except as so modified or superseded, to
constitute a part of this Registration Statement.
</DIV>

<DIV align="left" style="margin-top: 10pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt; background: transparent; color: #000000">
<TR>
    <TD width="7%"></TD>
    <TD width="1%"></TD>
    <TD></TD>
</TR>
<TR valign="top">
    <TD nowrap align="left"><B>Item&nbsp;4.</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Description of Securities.</B></TD>
</TR>
</TABLE>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">Not applicable.
</DIV>

<DIV align="left" style="margin-top: 10pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt; background: transparent; color: #000000">
<TR>
    <TD width="7%"></TD>
    <TD width="1%"></TD>
    <TD></TD>
</TR>
<TR valign="top">
    <TD nowrap align="left"><B>Item&nbsp;5.</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Interests of Named Experts and Counsel.</B></TD>
</TR>
</TABLE>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">Not applicable.
</DIV>
<P align="center" style="font-size: 10pt; text-indent: 4%">&nbsp;

<P align="center" style="font-size: 10pt"><!-- Folio -->2<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: 'Times New Roman',Times,serif; margin-left: .25in; width: 7.50in">

<DIV align="left" style="margin-top: 10pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt; background: transparent; color: #000000">
<TR>
    <TD width="7%"></TD>
    <TD width="1%"></TD>
    <TD></TD>
</TR>
<TR valign="top">
    <TD nowrap align="left"><B>Item&nbsp;6.</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Indemnification of Directors and Officers.</B></TD>
</TR>
</TABLE>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">Section&nbsp;145 of the General Corporation Law of Delaware provides, in summary, that the
directors and officers of the Registrant may, under certain circumstances, be indemnified by the
Registrant against all expenses incurred by or imposed upon them as a result of actions, suits or
proceedings brought against them as such directors and officers, or as directors or officers of any
other organization at the request of the Registrant, if they act in good faith and in a manner they
reasonably believe to be in or not opposed to the best interests of the Registrant, and with
respect to any criminal action or proceeding, have no reasonable cause to believe their conduct was
unlawful. No indemnification shall be made, however, against expenses with respect to any claim
issued or matter as to which such person shall have been adjudged to be liable to the Registrant
unless and only to the extent that the court in which such action or suit was brought shall
determine upon application that, despite the adjudication of liability but in view of all the
circumstances of the case, they are fairly and reasonably entitled to indemnity for such expenses
which such court shall deem proper. Section&nbsp;145 of the Delaware General Corporation Law also
provides that directors and officers of the Registrant are entitled to such indemnification by the
Registrant to the extent that such persons are successful on the merits or otherwise in defending
any such action, suit or proceeding. The Delaware General Corporation Law provides that Section
145 is not exclusive of other rights to which those seeking indemnification may be entitled under
any bylaw, agreement, vote of stockholders or disinterested directors or otherwise. The
Registrant&#146;s Amended and Restated Bylaws provide that (a)&nbsp;it shall indemnify its directors and
officers to the maximum extent and in the manner permitted by the Delaware General Corporation Law
against expenses (including attorneys&#146; fees), judgments, fines, ERISA excise taxes, settlements and
other amounts actually and reasonably incurred in connection with any proceeding, whether civil,
criminal, administrative or investigative, arising by reason of the fact that such person is or was
an agent of the corporation, subject to certain limited exceptions, (b)&nbsp;it shall advance expenses
incurred by any director or officer prior to the final disposition of any proceeding to which the
director or officer was or is or is threatened to be made a party promptly following a request
therefore, subject to certain limited exceptions, and (c)&nbsp;the rights conferred in the Registrant&#146;s
Bylaws are not exclusive.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">Section&nbsp;102 of the Delaware General Corporation Law permits a corporation to provide in its
certificate of incorporation that a director of the corporation shall not be personally liable to
the corporation or its stockholders for monetary damages for breach of fiduciary duty as a
director, except for liability (i)&nbsp;for any breach of the director&#146;s duty of loyalty to the
corporation or its stockholders, (ii)&nbsp;for acts or omissions not in good faith or which involve
intentional misconduct or a knowing violation of law, (iii)&nbsp;for unlawful payments of dividends or
unlawful stock repurchases, redemptions or other distributions, or (iv)&nbsp;for any transaction from
which the director derived an improper personal benefit. The Registrant&#146;s Amended and Restated
Certificate of Incorporation provides that, to the fullest extent permitted by the Delaware General
Corporation Law, (1)&nbsp;a director shall not be personally liable to the Registrant or its
stockholders for monetary damages for breach of fiduciary duty as a director, and (2)&nbsp;the
Registrant shall indemnify any director or officer made a party to an action or proceeding, whether
criminal, civil, administrative or investigative, by reason of the fact of such person&#146;s current or
prior service as a director or officer of the Registrant, any predecessor of the Registrant or any
other enterprise per the Registrant&#146;s or any predecessor to the Registrant&#146;s request.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">The Registrant has also entered into indemnification agreements with each of its directors and
executive officers to give such directors and officers additional contractual assurances regarding
the scope of the indemnification set forth in the Registrant&#146;s certificate of incorporation and
bylaws and to provide additional procedural protections. These agreements, among other things,
provide that generally the Registrant will indemnify its directors and executive officers for
expenses (including attorneys&#146; fees), judgments, fines, penalties and amounts paid in settlement
(including all interest, assessments and other charges paid or payable in connection therewith)
actually and reasonably incurred by a director or executive officer in connection with any action
or proceeding to which such person was, is or is threatened to be made a party, a witness or other
participant by reason of such person&#146;s services as a director or executive officer of the
Registrant, any of the Registrant&#146;s subsidiaries or any other company or enterprise to which the
person provides services at the Registrant&#146;s request, and any federal, state, local or foreign
taxes imposed on the director or executive officer as a result of the actual or deemed receipt of
any payments under the indemnification agreements. However, directors and executive officers shall
not be entitled to indemnification pursuant to such agreements in connection with any action or proceeding: (i)
initiated by the director or executive officer against the Registration or any director or
executive officer of the Registrant unless the Registrant has joined in or consented to the
initiation of such action or proceeding; (ii)&nbsp;made on account of the director or executive
officer&#146;s conduct which constitutes a breach of his or her duty of loyalty to the Registrant or its
stockholders or is an act or omission not in good faith or which involves intention misconduct or a
knowing violation of the law, or (iii)&nbsp;arising from the purchase and sale by the director or
executive officer of securities in violation of Section 16(b) of the Exchange Act, or (iv)&nbsp;not
permitted under applicable law.
</DIV>
<P align="center" style="font-size: 10pt; text-indent: 4%">&nbsp;

<P align="center" style="font-size: 10pt"><!-- Folio -->3<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: 'Times New Roman',Times,serif; margin-left: .25in; width: 7.50in">

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">In addition, the indemnification agreements provide that generally, upon the request of a
director or executive officer, the Registrant shall advance expenses (including attorneys&#146; fees) to
the director or officer, subject to the condition that the Registrant receives an undertaking to
repay any amount so advanced if it is ultimately determined that the person is not eligible for
indemnification. The Registrant intends to enter into indemnification agreements with any new
directors and executive officers in the future.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">The Registrant has also obtained an insurance policy covering its directors and officers with
respect to certain liabilities, including liabilities arising under the Securities Act.
</DIV>

<DIV align="left" style="margin-top: 10pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt; background: transparent; color: #000000">
<TR>
    <TD width="7%"></TD>
    <TD width="1%"></TD>
    <TD></TD>
</TR>
<TR valign="top">
    <TD nowrap align="left"><B>Item&nbsp;7.</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Exemption From Registration Claimed.</B></TD>
</TR>
</TABLE>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">Not applicable.
</DIV>

<DIV align="left" style="margin-top: 10pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt; background: transparent; color: #000000">
<TR>
    <TD width="7%"></TD>
    <TD width="1%"></TD>
    <TD></TD>
</TR>
<TR valign="top">
    <TD nowrap align="left"><B>Item&nbsp;8.</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Exhibits.</B></TD>
</TR>
</TABLE>
</DIV>
<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="5%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="86%">&nbsp;</TD>
</TR>
<TR style="font-size: 10pt" valign="bottom">
    <TD nowrap align="center" colspan="3" style="border-bottom: 1px solid #000000"><B>Exhibit No.</B></TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="left" style="border-bottom: 1px solid #000000"><B>Description of Document</B></TD>
</TR>

<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">4.1</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Amended and Restated Certificate of Incorporation of the Registrant (incorporated herein
by reference to Exhibit&nbsp;3.1 to the Registrant&#146;s Form&nbsp;10-K filed on March&nbsp;16, 2006 (SEC
file number 001-32157-06693266)).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">4.2</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Certificate of Amendment to the Amended and Restated Certificate of Incorporation of the
Registrant dated October&nbsp;5, 2009 (incorporated herein by reference to Exhibit&nbsp;3.1 to the
Registrant&#146;s Form&nbsp;8-K filed on October&nbsp;13, 2009 (SEC file number 001-32157-091115090)).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">4.3</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Certificate of Amendment to the Amended and Restated Certificate of Incorporation of the
Registrant, dated April&nbsp;23, 2010 (incorporated herein by reference to Exhibit&nbsp;3.1 to the
Registrant&#146;s Form&nbsp;8-K filed on April&nbsp;26, 2010 (SEC file number 001-32157-10769058)).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">4.4</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Amended and Restated Bylaws of the Registrant (incorporated herein by reference to
Exhibit&nbsp;3.1 to the Registrant&#146;s Form&nbsp;8-K filed on December&nbsp;15, 2008 (SEC file number
001-32157-081249921)).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">5.1</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Opinion of Sheppard, Mullin, Richter &#038; Hampton LLP.</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">23.1</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Consent of J.H. Cohn LLP, Independent Registered Public Accounting Firm.</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">23.2</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Consent of Sheppard, Mullin, Richter &#038; Hampton LLP (included in Exhibit&nbsp;5.1).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">24.1</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Power of Attorney (included as part of the signature page to this Registration Statement).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.1</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>

<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">ADVENTRX Pharmaceuticals, Inc. Amended and Restated 2008 Omnibus Incentive Plan.

</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.2</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Form of Non-Statutory Stock Option Grant Agreement (for directors) under the 2008 Omnibus
Incentive Plan (incorporated herein by reference to Exhibit&nbsp;10.5 to the Registrant&#146;s Form
10-Q filed on August&nbsp;11, 2008 (SEC file number 001-32157-081005744)).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.3</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Form of Non-Statutory/Incentive Stock Option Grant Agreement (for consultants/employees)
under the 2008 Omnibus Incentive Plan (incorporated herein by reference to Exhibit&nbsp;10.6
to the Registrant&#146;s Form&nbsp;10-Q filed on August&nbsp;11, 2008 (SEC file number
001-32157-081005744)).</DIV></TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>

<P align="center" style="font-size: 10pt">&nbsp;

<P align="center" style="font-size: 10pt"><!-- Folio -->4<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: 'Times New Roman',Times,serif; margin-left: .25in; width: 7.50in">

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="5%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="86%">&nbsp;</TD>
</TR>
<TR style="font-size: 10pt" valign="bottom">
    <TD nowrap align="center" colspan="3" style="border-bottom: 1px solid #000000"><B>Exhibit No.</B></TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="left" style="border-bottom: 1px solid #000000"><B>Description of Document</B></TD>
</TR>

<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.4</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Form of Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan (for
grant to Brian M. Culley in July&nbsp;2009) (incorporated herein by reference to Exhibit&nbsp;10.1
to the Registrant&#146;s Form&nbsp;8-K filed on July&nbsp;22, 2009 (SEC file number
001-32157-09957353)).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.5</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Form of Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan (for
grant to Patrick L. Keran in July&nbsp;2009) (incorporated herein by reference to Exhibit&nbsp;10.2
to the Registrant&#146;s Form&nbsp;8-K filed on July&nbsp;22, 2009 (SEC file number
001-32157-09957353)).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.6</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Form of letter, dated January&nbsp;20, 2010, modifying options granted to Brian M. Culley and
Patrick L. Keran in July&nbsp;2009 (incorporated herein by reference to Exhibit&nbsp;10.4 to the
Registrant&#146;s Form&nbsp;8-K filed on January&nbsp;26, 2010 (SEC file number 001-32157-10547818)).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.7</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Form of Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan (for
grant to Brian M. Culley in January&nbsp;2010) (incorporated herein by reference to Exhibit
10.1 to the Registrant&#146;s Form&nbsp;8-K filed on January&nbsp;26, 2010 (SEC file number
001-32157-10547818)).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.8</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Form of Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan (for
grant to Patrick L. Keran in January&nbsp;2010) (incorporated herein by reference to Exhibit
10.2 to the Registrant&#146;s Form&nbsp;8-K filed on January&nbsp;26, 2010 (SEC file number
001-32157-10547818)).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.9</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan, effective
as of February&nbsp;1, 2011, by and between the registrant and Brian
M. Culley (incorporated
herein by reference to Exhibit&nbsp;10.7 to the Registrant&#146;s Form&nbsp;10-Q filed on May&nbsp;9,
2011(SEC file number 001-32157-11823538).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.10</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan, effective
as of February&nbsp;1, 2011, by and between the Registrant and Patrick L. Keran (incorporated
herein by reference to Exhibit&nbsp;10.7 to the Registrant&#146;s Form&nbsp;10-Q filed on May&nbsp;9,
2011(SEC file number 001-32157-11823538).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.11</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Form of &#091;Non-Statutory&#093;&#091;Incentive&#093; Stock Option Grant Agreement (for
consultants/employees) under the Amended and Restated 2008 Omnibus Incentive Plan.</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.12</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Form of Non-Statutory Stock Option Grant Agreement &#151; Director under the Amended and
Restated 2008 Omnibus Incentive Plan.</DIV></TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>


<DIV align="left" style="margin-top: 10pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt; background: transparent; color: #000000">
<TR>
    <TD width="7%"></TD>
    <TD width="1%"></TD>
    <TD></TD>
</TR>
<TR valign="top">
    <TD nowrap align="left"><B>Item&nbsp;9.</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Undertakings.</B></TD>
</TR>
</TABLE>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">(a)&nbsp;The undersigned Registrant hereby undertakes:
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 10pt; margin-left: 8%">(1)&nbsp;To file, during any period in which offers or sales are being made, a
post-effective amendment to this Registration Statement:
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 10pt; margin-left: 12%">(i)&nbsp;to include any prospectus required by Section&nbsp;10(a)(3) of the Securities
Act;
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 10pt; margin-left: 12%">(ii)&nbsp;to reflect in the prospectus any facts or events arising after the
effective date of this Registration Statement (or the most recent
post-effective amendment thereof) which, individually or in the aggregate,
represent a fundamental change in the information set forth in this
Registration Statement. Notwithstanding the foregoing, any increase or
decrease in volume of securities offered (if the total dollar value of
securities offered would not exceed that which was registered) and any
deviation from the low or high end of the estimated maximum offering range
may be reflected in the form of prospectus filed with the Commission
pursuant to Rule 424(b) if, in the aggregate, the changes in volume and
price represent no more than a 20&nbsp;percent change in the maximum aggregate
offering price set forth in the &#147;Calculation of Registration Fee&#148; table in
the effective registration statement;
</DIV>
<P align="center" style="font-size: 10pt">&nbsp;

<P align="center" style="font-size: 10pt"><!-- Folio -->5<!-- /Folio -->
</DIV>

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<DIV style="font-family: 'Times New Roman',Times,serif; margin-left: .25in; width: 7.50in">


<DIV align="left" style="font-size: 10pt; margin-top: 10pt; margin-left: 12%">(iii)&nbsp;to include any material information with respect to the plan of
distribution not previously disclosed in this Registration Statement or any
material change to such information in this Registration Statement;
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; margin-left: 12%"><I>Provided, however</I>, that paragraphs (a)(1)(i) and (a)(1)(ii) do not apply if
the information required to be included in a post-effective amendment by
those paragraphs is contained in reports filed with or furnished to the
Commission by the Registrant pursuant to Section&nbsp;13 or Section 15(d) of the
Exchange Act that are incorporated by reference in this Registration
Statement.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; margin-left: 8%">(2)&nbsp;That, for the purpose of determining any liability under the Securities Act,
each such post-effective amendment shall be deemed to be a new registration
statement relating to the securities offered therein, and the offering of such
securities at that time shall be deemed to be the initial bona fide offering
thereof.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 10pt; margin-left: 8%">(3)&nbsp;To remove from registration by means of a post-effective amendment any of the
securities being registered which remain unsold at the termination of the offering.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">(b)&nbsp;The undersigned Registrant hereby undertakes that, for purposes of determining any
liability under the Securities Act, each filing of the Registrant&#146;s annual report pursuant to
Section 13(a) or Section 15(d) of the Exchange Act (and, where applicable, each filing of an
employee benefit plan&#146;s annual report pursuant to Section 15(d) of the Exchange Act) that is
incorporated by reference in the registration statement shall be deemed to be a new registration
statement relating to the securities offered therein, and the offering of such securities at that
time shall be deemed to be the initial bona fide offering thereof.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">(c)&nbsp;Insofar as indemnification for liabilities arising under the Securities Act may be
permitted to directors, officers and controlling persons of the Registrant pursuant to the
foregoing provisions, or otherwise, the Registrant has been advised that in the opinion of the
Securities and Exchange Commission such indemnification is against public policy as expressed in
the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification
against such liabilities (other than the payment by the Registrant of expenses incurred or paid by
a director, officer or controlling person of the Registrant in the successful defense of any
action, suit or proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the Registrant will, unless in the opinion of its
counsel the matter has been settled by controlling precedent, submit to a court of appropriate
jurisdiction the question whether such indemnification by it is against public policy as expressed
in the Securities Act and will be governed by the final adjudication of such issue.
</DIV>


<P align="center" style="font-size: 10pt">&nbsp;

<P align="center" style="font-size: 10pt"><!-- Folio -->6<!-- /Folio -->
</DIV>

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<DIV style="font-family: 'Times New Roman',Times,serif; margin-left: .25in; width: 7.50in">




<DIV align="left" style="font-size: 10pt; margin-top: 10pt"><B>SIGNATURES</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant
certifies that it has reasonable grounds to believe that it meets all of the requirements for
filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by
the undersigned, thereunto duly authorized, in the City of San Diego, State of California, on June
16, 2011.
</DIV>

<TABLE width="100%" border="0" cellspacing="0" cellpadding="0" style="font-size: 10pt">
<TR>
    <TD width="48%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="35%">&nbsp;</TD>
    <TD width="15%">&nbsp;</TD>
</TR>
<TR>
    <TD valign="top" align="left">&nbsp;</TD>
    <TD colspan="3" align="left"><B>ADVENTRX Pharmaceuticals, Inc.</B><BR>
&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">&nbsp;</TD>
    <TD valign="top">By:&nbsp;&nbsp;</TD>
    <TD colspan="2" style="border-bottom: 1px solid #000000" align="left">/s/ BRIAN M. CULLEY
&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD colspan="2" align="left">Brian M. Culley&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD colspan="2" align="left">Chief Executive Officer&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>

</TABLE>

<DIV align="center" style="font-size: 10pt; margin-top: 10pt"><B>POWER OF ATTORNEY</B>
</DIV>



<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below hereby
constitutes and appoints Brian M. Culley and Patrick L. Keran, and each of them acting
individually, as his true and lawful attorneys-in-fact and agents, each with full power of
substitution and resubstitution, for him and in his name, place and stead, in any and all
capacities, to sign: (1)&nbsp;this registration statement on Form S-8 under the Securities Act of 1933,
as amended (the &#147;Securities Act&#148;), in connection with the registration under the Securities Act of
shares of common stock of the Registrant to be issued in connection with the ADVENTRX
Pharmaceuticals, Inc. Amended and Restated 2008 Omnibus Incentive Plan; and (2)&nbsp;any one or more
amendments to any part of the foregoing registration statement, including any post-effective
amendments, or appendices or supplements that may be required to be
filed under the Securities Act to keep such registration statement effective or to terminate its effectiveness; and/or to file the
same, with all exhibits thereto and other documents in connection therewith, with the Securities
and Exchange Commission, granting unto said attorneys-in-fact and agents, full power and authority
to do and perform each and every act and thing requisite and necessary to be done in connection
therewith, as fully for all intents and purposes as he might or could do in person, hereby
ratifying and confirming all that said attorneys-in-fact and agents, or any of them or their
substitute or resubstitute, may lawfully do or cause to be done by virtue hereof.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">Pursuant to the requirements of the Securities Exchange Act of 1934, this report has been
signed by the following persons on behalf of the registrant and in the capacities and on the dates
indicated.
</DIV>
<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="35%">&nbsp;</TD>
    <TD width="2%">&nbsp;</TD>
    <TD width="40%">&nbsp;</TD>
    <TD width="2%">&nbsp;</TD>
    <TD width="22%">&nbsp;</TD>
</TR>
<TR style="font-size: 10pt" valign="bottom">
    <TD nowrap align="left" style="border-bottom: 1px solid #000000"><B>Name and Signature</B></TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" style="border-bottom: 1px solid #000000"><B>Title</B></TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" style="border-bottom: 1px solid #000000"><B>Date</B></TD>
</TR>

<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom"><!-- Blank Space -->

<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">

<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">/s/
BRIAN M. CULLEY
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Chief Executive Officer</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px"><DIV style="font-size: 1pt; border-top: 1px solid #000000">&nbsp;</DIV>
Brian M. Culley
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">(Principal Executive Officer)
</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">June&nbsp;16, 2011</TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">

<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">/s/
PATRICK L. KERAN
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">President and Chief Operating Officer</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px"><DIV style="font-size: 1pt; border-top: 1px solid #000000">&nbsp;</DIV>
Patrick L. Keran
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">(Principal Financial Officer)
</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">June&nbsp;16, 2011</TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">

<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">/s/
BRANDI L. ROBERTS
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Vice President, Finance</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px"><DIV style="font-size: 1pt; border-top: 1px solid #000000">&nbsp;</DIV>
Brandi L. Roberts
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">(Principal Accounting Officer)
</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">June&nbsp;16, 2011</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>

<P align="center" style="font-size: 10pt">&nbsp;

<P align="center" style="font-size: 10pt"><!-- Folio -->7<!-- /Folio -->
</DIV>

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<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: 'Times New Roman',Times,serif; margin-left: .25in; width: 7.50in">

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="35%">&nbsp;</TD>
    <TD width="2%">&nbsp;</TD>
    <TD width="40%">&nbsp;</TD>
    <TD width="2%">&nbsp;</TD>
    <TD width="22%">&nbsp;</TD>
</TR>
<TR style="font-size: 10pt" valign="bottom">
    <TD nowrap align="left" style="border-bottom: 1px solid #000000"><B>Name and Signature</B></TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" style="border-bottom: 1px solid #000000"><B>Title</B></TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" style="border-bottom: 1px solid #000000"><B>Date</B></TD>
</TR>

<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom"><!-- Blank Space -->
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">

<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">/s/
JACK LIEF
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Chair of the Board</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px"><DIV style="font-size: 1pt; border-top: 1px solid #000000">&nbsp;</DIV>
Jack Lief
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;
</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">June&nbsp;16, 2011</TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">

<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">/s/
DAVID A. RAMSAY
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Director</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px"><DIV style="font-size: 1pt; border-top: 1px solid #000000">&nbsp;</DIV>
David A. Ramsay
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;
</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">June&nbsp;16, 2011</TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">

<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">/s/
LEWIS J. SHUSTER
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Director</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px"><DIV style="font-size: 1pt; border-top: 1px solid #000000">&nbsp;</DIV>
Lewis J. Shuster
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;
</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">June&nbsp;16, 2011</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>

<P align="center" style="font-size: 10pt">&nbsp;

<P align="center" style="font-size: 10pt"><!-- Folio -->8<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: 'Times New Roman',Times,serif; margin-left: .25in; width: 7.50in">


<DIV align="center" style="font-size: 10pt; margin-top: 10pt"><B>INDEX TO EXHIBITS</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 10pt; text-indent: 4%">The following documents are filed as exhibits to this registration statement:
</DIV>
<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="5%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="86%">&nbsp;</TD>
</TR>
<TR style="font-size: 10pt" valign="bottom">
    <TD nowrap align="center" colspan="3" style="border-bottom: 1px solid #000000"><B>Exhibit No.</B></TD>

    <TD>&nbsp;</TD>
    <TD nowrap align="left" style="border-bottom: 1px solid #000000"><B>Description of Document</B></TD>
</TR>

<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">4.1</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Amended and Restated Certificate of Incorporation of the Registrant (incorporated herein
by reference to Exhibit&nbsp;3.1 to the Registrant&#146;s Form&nbsp;10-K filed on March&nbsp;16, 2006 (SEC
file number 001-32157-06693266)).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">4.2</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Certificate of Amendment to the Amended and Restated Certificate of Incorporation of the
Registrant dated October&nbsp;5, 2009 (incorporated herein by reference to Exhibit&nbsp;3.1 to the
Registrant&#146;s Form&nbsp;8-K filed on October&nbsp;13, 2009 (SEC file number 001-32157-091115090)).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">4.3</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Certificate of Amendment to the Amended and Restated Certificate of Incorporation of the
Registrant, dated April&nbsp;23, 2010 (incorporated herein by reference to Exhibit&nbsp;3.1 to the
Registrant&#146;s Form&nbsp;8-K filed on April&nbsp;26, 2010 (SEC file number 001-32157-10769058)).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">4.4</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Amended and Restated Bylaws of the Registrant (incorporated herein by reference to
Exhibit&nbsp;3.1 to the Registrant&#146;s Form&nbsp;8-K filed on December&nbsp;15, 2008 (SEC file number
001-32157-081249921)).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">5.1</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Opinion of Sheppard, Mullin, Richter &#038; Hampton LLP.</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">23.1</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Consent of J.H. Cohn LLP, Independent Registered Public Accounting Firm.</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">23.2</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Consent of Sheppard, Mullin, Richter &#038; Hampton LLP (included in Exhibit&nbsp;5.1).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">24.1</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Power of Attorney (included as part of the signature page to this Registration Statement).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.1</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">ADVENTRX Pharmaceuticals, Inc. Amended and Restated 2008 Omnibus Incentive Plan.</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.2</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Form of Non-Statutory Stock Option Grant Agreement (for directors) under the 2008 Omnibus
Incentive Plan (incorporated herein by reference to Exhibit&nbsp;10.5 to the Registrant&#146;s Form
10-Q filed on August&nbsp;11, 2008 (SEC file number 001-32157-081005744)).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.3</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Form of Non-Statutory/Incentive Stock Option Grant Agreement (for consultants/employees)
under the 2008 Omnibus Incentive Plan (incorporated herein by reference to Exhibit&nbsp;10.6
to the Registrant&#146;s Form&nbsp;10-Q filed on August&nbsp;11, 2008 (SEC file number
001-32157-081005744)).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.4</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Form of Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan (for
grant to Brian M. Culley in July&nbsp;2009) (incorporated herein by reference to Exhibit&nbsp;10.1
to the Registrant&#146;s Form&nbsp;8-K filed on July&nbsp;22, 2009 (SEC file number
001-32157-09957353)).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.5</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Form of Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan (for
grant to Patrick L. Keran in July&nbsp;2009) (incorporated herein by reference to Exhibit&nbsp;10.2
to the Registrant&#146;s Form&nbsp;8-K filed on July&nbsp;22, 2009 (SEC file number
001-32157-09957353)).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.6</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Form of letter, dated January&nbsp;20, 2010, modifying options granted to Brian M. Culley and
Patrick L. Keran in July&nbsp;2009 (incorporated herein by reference to Exhibit&nbsp;10.4 to the
Registrant&#146;s Form&nbsp;8-K filed on January&nbsp;26, 2010 (SEC file number 001-32157-10547818)).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.7</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Form of Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan (for
grant to Brian M. Culley in January&nbsp;2010) (incorporated herein by reference to Exhibit
10.1 to the Registrant&#146;s Form&nbsp;8-K filed on January&nbsp;26, 2010 (SEC file number
001-32157-10547818)).</DIV></TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>

<P align="center" style="font-size: 10pt">&nbsp;

<P align="center" style="font-size: 10pt"><!-- Folio -->9<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: 'Times New Roman',Times,serif; margin-left: .25in; width: 7.50in">

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="5%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="86%">&nbsp;</TD>
</TR>
<TR style="font-size: 10pt" valign="bottom">
    <TD nowrap align="center" colspan="3" style="border-bottom: 1px solid #000000"><B>Exhibit No.</B></TD>

    <TD>&nbsp;</TD>
    <TD nowrap align="left" style="border-bottom: 1px solid #000000"><B>Description of Document</B></TD>
</TR>

<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.8</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Form of Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan (for
grant to Patrick L. Keran in January&nbsp;2010) (incorporated herein by reference to Exhibit
10.2 to the Registrant&#146;s Form&nbsp;8-K filed on January&nbsp;26, 2010 (SEC file number
001-32157-10547818)).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.9</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan, effective
as of February&nbsp;1, 2011, by and between the registrant and Brian
M. Culley (incorporated
herein by reference to Exhibit&nbsp;10.7 to the Registrant&#146;s Form&nbsp;10-Q filed on May&nbsp;9,
2011(SEC file number 001-32157-11823538).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.10</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan, effective
as of February&nbsp;1, 2011, by and between the Registrant and Patrick L. Keran (incorporated
herein by reference to Exhibit&nbsp;10.7 to the Registrant&#146;s Form&nbsp;10-Q filed on May&nbsp;9,
2011(SEC file number 001-32157-11823538).</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.11</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Form of &#091;Non-Statutory&#093;&#091;Incentive&#093; Stock Option Grant Agreement (for
consultants/employees) under the Amended and Restated 2008 Omnibus Incentive Plan.</DIV></TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
</TR>
<TR valign="bottom">
    <TD nowrap align="left" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">99.12</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Form of Non-Statutory Stock Option Grant Agreement &#151; Director under the Amended and
Restated 2008 Omnibus Incentive Plan.</DIV></TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>

<P align="center" style="font-size: 10pt">&nbsp;

<P align="center" style="font-size: 10pt"><!-- Folio -->10<!-- /Folio -->
</DIV>

</BODY>
</HTML>
[{"type": "S-8", "sequence": "1", "filename": "c18747sv8.htm", "description": "FORM S-8", "secsgml_size_bytes": 85076}]
{"company-data": {"conformed-name": "ADVENTRX PHARMACEUTICALS INC", "cik": "0001160308", "assigned-sic": "2834", "irs-number": "841318182", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-174940", "film-number": "11914946"}, "business-address": {"street1": "12390 EL CAMINO REAL", "street2": "SUITE 150", "city": "SAN DIEGO", "state": "CA", "zip": "92130", "phone": "8585520866"}, "mail-address": {"street1": "12390 EL CAMINO REAL", "street2": "SUITE 150", "city": "SAN DIEGO", "state": "CA", "zip": "92130"}, "former-company": {"former-conformed-name": "BIOKEYS PHARMACEUTICALS INC", "date-changed": "20010928"}}
Form S-8
As Filed with the Securities and Exchange Commission on June 16, 2011
Registration No. 333-
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-8
REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933
ADVENTRX Pharmaceuticals, Inc.
(Exact name of registrant as specified in its charter)
Delaware
(State or other jurisdiction of
incorporation or organization)
84-1318182
(I.R.S. Employer
Identification No.)
12390 El Camino Real, Suite 150
San Diego, California
92130
(Address of Principal Executive Offices)
(Zip Code)
ADVENTRX Pharmaceuticals, Inc. Amended and Restated 2008 Omnibus Incentive Plan
(Full title of the plans)
Brian M. Culley
Chief Executive Officer
ADVENTRX Pharmaceuticals, Inc.
12390 El Camino Real, Suite 150
San Diego, California, 92130
(Name and Address of Agent For Service)
(858) 552-0866
(Telephone number, including area code, of agent for service)
Copies to:
Patrick L. Keran
Kirt W. Shuldberg, Esq.
President and Chief Operating Officer and
Sheppard, Mullin, Richter
& Hampton LLP
Principal Financial Officer
12275 El Camino Real,
Suite 200
ADVENTRX Pharmaceuticals, Inc.
San Diego, CA 92130
12390 El Camino Real, Suite 150
(858) 720-8900
San Diego, California, 92130
(858) 552-0866
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a
non-accelerated filer, or a smaller reporting company. See the definitions of "large accelerated
filer," "accelerated filer," and "smaller reporting company" in Rule 12b-2 of the Exchange Act.
(Check one):
Large Accelerated filer
o
Accelerated filer
o
Non-accelerated filer
o
(Do not check if a smaller reporting company)
Smaller reporting company
þ
CALCULATION OF REGISTRATION FEE
Proposed
Maximum
Proposed Maximum
Amount to be
Offering Price
Aggregate Offering
Amount of
Title of Securities to be Registered
Registered (1)
Per Share
Price
Registration Fee
Common Stock, par value $0.001 per
share: To be issued under the ADVENTRX
Pharmaceuticals, Inc. Amended and
Restated 2008 Omnibus Incentive Plan (2)
3,637,415 shares
$
2.35
(3)
$
8,547,925
(3)
$
992.41
(1)
Pursuant to Rule 416 under the Securities Act of 1933,
as amended (the "Securities Act"), this Registration
Statement shall also cover any additional shares of common
stock which become issuable under the ADVENTRX
Pharmaceuticals, Inc. Amended and Restated 2008 Omnibus
Incentive Plan (the "2008 Plan"), by reason of any stock
split, stock dividend, recapitalization or any other similar
transaction, effected without receipt of consideration,
which results in an increase in the Registrant's outstanding
shares of common stock.
(2)
Represents 3,637,415 additional shares of the
Registrant's common stock that became available for issuance
on June 15, 2011 under the 2008 Plan, which shares are in
addition to the 523,900 shares of common stock (on a
post-April 23, 2010 reverse stock split basis) registered on
the Registrant's Form S-8 filed with the Securities and
Exchange Commission (the "SEC") on June 25, 2008 (Commission
File No. 333-151903).
(3)
Estimated pursuant to Rules 457(c) and 457(h) under the
Securities Act solely for the purpose of calculating the
registration fee, based on the average of the high and low
prices of the Registrant's common stock as reported on the
NYSE Amex Equities on June 13, 2011.
The Registration Statement shall become effective upon filing in accordance with Rule 462(a)
under the Securities Act.
PART I
INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS
Item 1.
Plan Information.*
Item 2.
Registrant Information and Employee Program Annual Information.*
*
Information required by Part I to be contained in the Section 10(a) prospectus is omitted from
this Registration Statement in accordance with Rule 428 under the Securities Act and the Note to
Part I of Form S-8.
PART II
INFORMATION REQUIRED IN REGISTRATION STATEMENT
Item 3.
Incorporation of Documents by Reference.
The SEC allows the Registrant to "incorporate by reference" the information that the
Registrant files with them, which means that the Registrant can disclose important information by
reference to those documents. The information incorporated by reference is considered to be part
of this Registration Statement, and later information filed with the SEC will update and supersede
this information. The following documents filed by the Registrant with the SEC are hereby
incorporated by reference into this Registration Statement:
(a)
The Registrant's Annual Report on Form 10-K for the fiscal year ended December
31, 2010, filed with the SEC on March 10, 2011, including all material incorporated by
reference therein;
(b)
The Registrant's Quarterly Report on Form 10-Q for the quarter ended March 31,
2011, filed with the SEC on May 9, 2011, including all material incorporated by
reference therein;
(c)
The Registrant's Current Reports on Form 8-K filed on March 10, 2011, March 22,
2011, April 11, 2011 and May 9, 2011, including all material incorporated by reference
therein; and
(d)
The description of the Registrant's common stock contained in the Registrant's
Registration Statement on Form 8-A (File No. 001-32157) filed with the SEC on April
27, 2004, pursuant to Section 12(b) of the Securities Exchange Act of 1934, as amended
(the "Exchange Act"), including any amendments or reports filed for the purpose of
updating such descriptions.
In addition, all documents subsequently filed by the Registrant pursuant to Sections 13(a),
13(c), 14 and 15(d) of the Exchange Act, after the date of this Registration Statement and prior to
the filing of a post-effective amendment which indicates that all securities offered have been sold
or which deregisters all securities then remaining unsold, will be incorporated by reference into
this Registration Statement from the date of filing of such documents.
Any statement contained in a document incorporated or deemed to be incorporated by reference
herein shall be deemed to be modified or superseded for the purposes of this Registration Statement
to the extent that a statement contained herein or in any other subsequently filed document which
also is or deemed to be incorporated by reference herein modifies or supersedes such statement. Any
statement so modified or superseded shall not be deemed, except as so modified or superseded, to
constitute a part of this Registration Statement.
Item 4.
Description of Securities.
Not applicable.
Item 5.
Interests of Named Experts and Counsel.
Not applicable.
2
Item 6.
Indemnification of Directors and Officers.
Section 145 of the General Corporation Law of Delaware provides, in summary, that the
directors and officers of the Registrant may, under certain circumstances, be indemnified by the
Registrant against all expenses incurred by or imposed upon them as a result of actions, suits or
proceedings brought against them as such directors and officers, or as directors or officers of any
other organization at the request of the Registrant, if they act in good faith and in a manner they
reasonably believe to be in or not opposed to the best interests of the Registrant, and with
respect to any criminal action or proceeding, have no reasonable cause to believe their conduct was
unlawful. No indemnification shall be made, however, against expenses with respect to any claim
issued or matter as to which such person shall have been adjudged to be liable to the Registrant
unless and only to the extent that the court in which such action or suit was brought shall
determine upon application that, despite the adjudication of liability but in view of all the
circumstances of the case, they are fairly and reasonably entitled to indemnity for such expenses
which such court shall deem proper. Section 145 of the Delaware General Corporation Law also
provides that directors and officers of the Registrant are entitled to such indemnification by the
Registrant to the extent that such persons are successful on the merits or otherwise in defending
any such action, suit or proceeding. The Delaware General Corporation Law provides that Section
145 is not exclusive of other rights to which those seeking indemnification may be entitled under
any bylaw, agreement, vote of stockholders or disinterested directors or otherwise. The
Registrant's Amended and Restated Bylaws provide that (a) it shall indemnify its directors and
officers to the maximum extent and in the manner permitted by the Delaware General Corporation Law
against expenses (including attorneys' fees), judgments, fines, ERISA excise taxes, settlements and
other amounts actually and reasonably incurred in connection with any proceeding, whether civil,
criminal, administrative or investigative, arising by reason of the fact that such person is or was
an agent of the corporation, subject to certain limited exceptions, (b) it shall advance expenses
incurred by any director or officer prior to the final disposition of any proceeding to which the
director or officer was or is or is threatened to be made a party promptly following a request
therefore, subject to certain limited exceptions, and (c) the rights conferred in the Registrant's
Bylaws are not exclusive.
Section 102 of the Delaware General Corporation Law permits a corporation to provide in its
certificate of incorporation that a director of the corporation shall not be personally liable to
the corporation or its stockholders for monetary damages for breach of fiduciary duty as a
director, except for liability (i) for any breach of the director's duty of loyalty to the
corporation or its stockholders, (ii) for acts or omissions not in good faith or which involve
intentional misconduct or a knowing violation of law, (iii) for unlawful payments of dividends or
unlawful stock repurchases, redemptions or other distributions, or (iv) for any transaction from
which the director derived an improper personal benefit. The Registrant's Amended and Restated
Certificate of Incorporation provides that, to the fullest extent permitted by the Delaware General
Corporation Law, (1) a director shall not be personally liable to the Registrant or its
stockholders for monetary damages for breach of fiduciary duty as a director, and (2) the
Registrant shall indemnify any director or officer made a party to an action or proceeding, whether
criminal, civil, administrative or investigative, by reason of the fact of such person's current or
prior service as a director or officer of the Registrant, any predecessor of the Registrant or any
other enterprise per the Registrant's or any predecessor to the Registrant's request.
The Registrant has also entered into indemnification agreements with each of its directors and
executive officers to give such directors and officers additional contractual assurances regarding
the scope of the indemnification set forth in the Registrant's certificate of incorporation and
bylaws and to provide additional procedural protections. These agreements, among other things,
provide that generally the Registrant will indemnify its directors and executive officers for
expenses (including attorneys' fees), judgments, fines, penalties and amounts paid in settlement
(including all interest, assessments and other charges paid or payable in connection therewith)
actually and reasonably incurred by a director or executive officer in connection with any action
or proceeding to which such person was, is or is threatened to be made a party, a witness or other
participant by reason of such person's services as a director or executive officer of the
Registrant, any of the Registrant's subsidiaries or any other company or enterprise to which the
person provides services at the Registrant's request, and any federal, state, local or foreign
taxes imposed on the director or executive officer as a result of the actual or deemed receipt of
any payments under the indemnification agreements. However, directors and executive officers shall
not be entitled to indemnification pursuant to such agreements in connection with any action or proceeding: (i)
initiated by the director or executive officer against the Registration or any director or
executive officer of the Registrant unless the Registrant has joined in or consented to the
initiation of such action or proceeding; (ii) made on account of the director or executive
officer's conduct which constitutes a breach of his or her duty of loyalty to the Registrant or its
stockholders or is an act or omission not in good faith or which involves intention misconduct or a
knowing violation of the law, or (iii) arising from the purchase and sale by the director or
executive officer of securities in violation of Section 16(b) of the Exchange Act, or (iv) not
permitted under applicable law.
3
In addition, the indemnification agreements provide that generally, upon the request of a
director or executive officer, the Registrant shall advance expenses (including attorneys' fees) to
the director or officer, subject to the condition that the Registrant receives an undertaking to
repay any amount so advanced if it is ultimately determined that the person is not eligible for
indemnification. The Registrant intends to enter into indemnification agreements with any new
directors and executive officers in the future.
The Registrant has also obtained an insurance policy covering its directors and officers with
respect to certain liabilities, including liabilities arising under the Securities Act.
Item 7.
Exemption From Registration Claimed.
Not applicable.
Item 8.
Exhibits.
Exhibit No.
Description of Document
4.1
Amended and Restated Certificate of Incorporation of the Registrant (incorporated herein
by reference to Exhibit 3.1 to the Registrant's Form 10-K filed on March 16, 2006 (SEC
file number 001-32157-06693266)).
4.2
Certificate of Amendment to the Amended and Restated Certificate of Incorporation of the
Registrant dated October 5, 2009 (incorporated herein by reference to Exhibit 3.1 to the
Registrant's Form 8-K filed on October 13, 2009 (SEC file number 001-32157-091115090)).
4.3
Certificate of Amendment to the Amended and Restated Certificate of Incorporation of the
Registrant, dated April 23, 2010 (incorporated herein by reference to Exhibit 3.1 to the
Registrant's Form 8-K filed on April 26, 2010 (SEC file number 001-32157-10769058)).
4.4
Amended and Restated Bylaws of the Registrant (incorporated herein by reference to
Exhibit 3.1 to the Registrant's Form 8-K filed on December 15, 2008 (SEC file number
001-32157-081249921)).
5.1
Opinion of Sheppard, Mullin, Richter & Hampton LLP.
23.1
Consent of J.H. Cohn LLP, Independent Registered Public Accounting Firm.
23.2
Consent of Sheppard, Mullin, Richter & Hampton LLP (included in Exhibit 5.1).
24.1
Power of Attorney (included as part of the signature page to this Registration Statement).
99.1
ADVENTRX Pharmaceuticals, Inc. Amended and Restated 2008 Omnibus Incentive Plan.
99.2
Form of Non-Statutory Stock Option Grant Agreement (for directors) under the 2008 Omnibus
Incentive Plan (incorporated herein by reference to Exhibit 10.5 to the Registrant's Form
10-Q filed on August 11, 2008 (SEC file number 001-32157-081005744)).
99.3
Form of Non-Statutory/Incentive Stock Option Grant Agreement (for consultants/employees)
under the 2008 Omnibus Incentive Plan (incorporated herein by reference to Exhibit 10.6
to the Registrant's Form 10-Q filed on August 11, 2008 (SEC file number
001-32157-081005744)).
4
Exhibit No.
Description of Document
99.4
Form of Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan (for
grant to Brian M. Culley in July 2009) (incorporated herein by reference to Exhibit 10.1
to the Registrant's Form 8-K filed on July 22, 2009 (SEC file number
001-32157-09957353)).
99.5
Form of Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan (for
grant to Patrick L. Keran in July 2009) (incorporated herein by reference to Exhibit 10.2
to the Registrant's Form 8-K filed on July 22, 2009 (SEC file number
001-32157-09957353)).
99.6
Form of letter, dated January 20, 2010, modifying options granted to Brian M. Culley and
Patrick L. Keran in July 2009 (incorporated herein by reference to Exhibit 10.4 to the
Registrant's Form 8-K filed on January 26, 2010 (SEC file number 001-32157-10547818)).
99.7
Form of Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan (for
grant to Brian M. Culley in January 2010) (incorporated herein by reference to Exhibit
10.1 to the Registrant's Form 8-K filed on January 26, 2010 (SEC file number
001-32157-10547818)).
99.8
Form of Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan (for
grant to Patrick L. Keran in January 2010) (incorporated herein by reference to Exhibit
10.2 to the Registrant's Form 8-K filed on January 26, 2010 (SEC file number
001-32157-10547818)).
99.9
Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan, effective
as of February 1, 2011, by and between the registrant and Brian
M. Culley (incorporated
herein by reference to Exhibit 10.7 to the Registrant's Form 10-Q filed on May 9,
2011(SEC file number 001-32157-11823538).
99.10
Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan, effective
as of February 1, 2011, by and between the Registrant and Patrick L. Keran (incorporated
herein by reference to Exhibit 10.7 to the Registrant's Form 10-Q filed on May 9,
2011(SEC file number 001-32157-11823538).
99.11
Form of [Non-Statutory][Incentive] Stock Option Grant Agreement (for
consultants/employees) under the Amended and Restated 2008 Omnibus Incentive Plan.
99.12
Form of Non-Statutory Stock Option Grant Agreement — Director under the Amended and
Restated 2008 Omnibus Incentive Plan.
Item 9.
Undertakings.
(a) The undersigned Registrant hereby undertakes:
(1) To file, during any period in which offers or sales are being made, a
post-effective amendment to this Registration Statement:
(i) to include any prospectus required by Section 10(a)(3) of the Securities
Act;
(ii) to reflect in the prospectus any facts or events arising after the
effective date of this Registration Statement (or the most recent
post-effective amendment thereof) which, individually or in the aggregate,
represent a fundamental change in the information set forth in this
Registration Statement. Notwithstanding the foregoing, any increase or
decrease in volume of securities offered (if the total dollar value of
securities offered would not exceed that which was registered) and any
deviation from the low or high end of the estimated maximum offering range
may be reflected in the form of prospectus filed with the Commission
pursuant to Rule 424(b) if, in the aggregate, the changes in volume and
price represent no more than a 20 percent change in the maximum aggregate
offering price set forth in the "Calculation of Registration Fee" table in
the effective registration statement;
5
(iii) to include any material information with respect to the plan of
distribution not previously disclosed in this Registration Statement or any
material change to such information in this Registration Statement;
Provided, however
, that paragraphs (a)(1)(i) and (a)(1)(ii) do not apply if
the information required to be included in a post-effective amendment by
those paragraphs is contained in reports filed with or furnished to the
Commission by the Registrant pursuant to Section 13 or Section 15(d) of the
Exchange Act that are incorporated by reference in this Registration
Statement.
(2) That, for the purpose of determining any liability under the Securities Act,
each such post-effective amendment shall be deemed to be a new registration
statement relating to the securities offered therein, and the offering of such
securities at that time shall be deemed to be the initial bona fide offering
thereof.
(3) To remove from registration by means of a post-effective amendment any of the
securities being registered which remain unsold at the termination of the offering.
(b) The undersigned Registrant hereby undertakes that, for purposes of determining any
liability under the Securities Act, each filing of the Registrant's annual report pursuant to
Section 13(a) or Section 15(d) of the Exchange Act (and, where applicable, each filing of an
employee benefit plan's annual report pursuant to Section 15(d) of the Exchange Act) that is
incorporated by reference in the registration statement shall be deemed to be a new registration
statement relating to the securities offered therein, and the offering of such securities at that
time shall be deemed to be the initial bona fide offering thereof.
(c) Insofar as indemnification for liabilities arising under the Securities Act may be
permitted to directors, officers and controlling persons of the Registrant pursuant to the
foregoing provisions, or otherwise, the Registrant has been advised that in the opinion of the
Securities and Exchange Commission such indemnification is against public policy as expressed in
the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification
against such liabilities (other than the payment by the Registrant of expenses incurred or paid by
a director, officer or controlling person of the Registrant in the successful defense of any
action, suit or proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the Registrant will, unless in the opinion of its
counsel the matter has been settled by controlling precedent, submit to a court of appropriate
jurisdiction the question whether such indemnification by it is against public policy as expressed
in the Securities Act and will be governed by the final adjudication of such issue.
6
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant
certifies that it has reasonable grounds to believe that it meets all of the requirements for
filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by
the undersigned, thereunto duly authorized, in the City of San Diego, State of California, on June
16, 2011.
ADVENTRX Pharmaceuticals, Inc.
By:
/s/ BRIAN M. CULLEY
Brian M. Culley
Chief Executive Officer
POWER OF ATTORNEY
KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below hereby
constitutes and appoints Brian M. Culley and Patrick L. Keran, and each of them acting
individually, as his true and lawful attorneys-in-fact and agents, each with full power of
substitution and resubstitution, for him and in his name, place and stead, in any and all
capacities, to sign: (1) this registration statement on Form S-8 under the Securities Act of 1933,
as amended (the "Securities Act"), in connection with the registration under the Securities Act of
shares of common stock of the Registrant to be issued in connection with the ADVENTRX
Pharmaceuticals, Inc. Amended and Restated 2008 Omnibus Incentive Plan; and (2) any one or more
amendments to any part of the foregoing registration statement, including any post-effective
amendments, or appendices or supplements that may be required to be
filed under the Securities Act to keep such registration statement effective or to terminate its effectiveness; and/or to file the
same, with all exhibits thereto and other documents in connection therewith, with the Securities
and Exchange Commission, granting unto said attorneys-in-fact and agents, full power and authority
to do and perform each and every act and thing requisite and necessary to be done in connection
therewith, as fully for all intents and purposes as he might or could do in person, hereby
ratifying and confirming all that said attorneys-in-fact and agents, or any of them or their
substitute or resubstitute, may lawfully do or cause to be done by virtue hereof.
Pursuant to the requirements of the Securities Exchange Act of 1934, this report has been
signed by the following persons on behalf of the registrant and in the capacities and on the dates
indicated.
Name and Signature
Title
Date
/s/
BRIAN M. CULLEY
Chief Executive Officer
Brian M. Culley
(Principal Executive Officer)
June 16, 2011
/s/
PATRICK L. KERAN
President and Chief Operating Officer
Patrick L. Keran
(Principal Financial Officer)
June 16, 2011
/s/
BRANDI L. ROBERTS
Vice President, Finance
Brandi L. Roberts
(Principal Accounting Officer)
June 16, 2011
7
Name and Signature
Title
Date
/s/
JACK LIEF
Chair of the Board
Jack Lief
June 16, 2011
/s/
DAVID A. RAMSAY
Director
David A. Ramsay
June 16, 2011
/s/
LEWIS J. SHUSTER
Director
Lewis J. Shuster
June 16, 2011
8
INDEX TO EXHIBITS
The following documents are filed as exhibits to this registration statement:
Exhibit No.
Description of Document
4.1
Amended and Restated Certificate of Incorporation of the Registrant (incorporated herein
by reference to Exhibit 3.1 to the Registrant's Form 10-K filed on March 16, 2006 (SEC
file number 001-32157-06693266)).
4.2
Certificate of Amendment to the Amended and Restated Certificate of Incorporation of the
Registrant dated October 5, 2009 (incorporated herein by reference to Exhibit 3.1 to the
Registrant's Form 8-K filed on October 13, 2009 (SEC file number 001-32157-091115090)).
4.3
Certificate of Amendment to the Amended and Restated Certificate of Incorporation of the
Registrant, dated April 23, 2010 (incorporated herein by reference to Exhibit 3.1 to the
Registrant's Form 8-K filed on April 26, 2010 (SEC file number 001-32157-10769058)).
4.4
Amended and Restated Bylaws of the Registrant (incorporated herein by reference to
Exhibit 3.1 to the Registrant's Form 8-K filed on December 15, 2008 (SEC file number
001-32157-081249921)).
5.1
Opinion of Sheppard, Mullin, Richter & Hampton LLP.
23.1
Consent of J.H. Cohn LLP, Independent Registered Public Accounting Firm.
23.2
Consent of Sheppard, Mullin, Richter & Hampton LLP (included in Exhibit 5.1).
24.1
Power of Attorney (included as part of the signature page to this Registration Statement).
99.1
ADVENTRX Pharmaceuticals, Inc. Amended and Restated 2008 Omnibus Incentive Plan.
99.2
Form of Non-Statutory Stock Option Grant Agreement (for directors) under the 2008 Omnibus
Incentive Plan (incorporated herein by reference to Exhibit 10.5 to the Registrant's Form
10-Q filed on August 11, 2008 (SEC file number 001-32157-081005744)).
99.3
Form of Non-Statutory/Incentive Stock Option Grant Agreement (for consultants/employees)
under the 2008 Omnibus Incentive Plan (incorporated herein by reference to Exhibit 10.6
to the Registrant's Form 10-Q filed on August 11, 2008 (SEC file number
001-32157-081005744)).
99.4
Form of Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan (for
grant to Brian M. Culley in July 2009) (incorporated herein by reference to Exhibit 10.1
to the Registrant's Form 8-K filed on July 22, 2009 (SEC file number
001-32157-09957353)).
99.5
Form of Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan (for
grant to Patrick L. Keran in July 2009) (incorporated herein by reference to Exhibit 10.2
to the Registrant's Form 8-K filed on July 22, 2009 (SEC file number
001-32157-09957353)).
99.6
Form of letter, dated January 20, 2010, modifying options granted to Brian M. Culley and
Patrick L. Keran in July 2009 (incorporated herein by reference to Exhibit 10.4 to the
Registrant's Form 8-K filed on January 26, 2010 (SEC file number 001-32157-10547818)).
99.7
Form of Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan (for
grant to Brian M. Culley in January 2010) (incorporated herein by reference to Exhibit
10.1 to the Registrant's Form 8-K filed on January 26, 2010 (SEC file number
001-32157-10547818)).
9
Exhibit No.
Description of Document
99.8
Form of Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan (for
grant to Patrick L. Keran in January 2010) (incorporated herein by reference to Exhibit
10.2 to the Registrant's Form 8-K filed on January 26, 2010 (SEC file number
001-32157-10547818)).
99.9
Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan, effective
as of February 1, 2011, by and between the registrant and Brian
M. Culley (incorporated
herein by reference to Exhibit 10.7 to the Registrant's Form 10-Q filed on May 9,
2011(SEC file number 001-32157-11823538).
99.10
Incentive Stock Option Grant Agreement under the 2008 Omnibus Incentive Plan, effective
as of February 1, 2011, by and between the Registrant and Patrick L. Keran (incorporated
herein by reference to Exhibit 10.7 to the Registrant's Form 10-Q filed on May 9,
2011(SEC file number 001-32157-11823538).
99.11
Form of [Non-Statutory][Incentive] Stock Option Grant Agreement (for
consultants/employees) under the Amended and Restated 2008 Omnibus Incentive Plan.
99.12
Form of Non-Statutory Stock Option Grant Agreement — Director under the Amended and
Restated 2008 Omnibus Incentive Plan.
10