<PAGE>

     As filed with the Securities and Exchange Commission on August 11, 2006.
                                                           Registration No. 333-

                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                    FORM S-8
                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933

                               CAMBREX CORPORATION
               (Exact name of issuer as specified in its charter)

                  Delaware                           22-2476135
          (State of Incorporation)      (I.R.S. Employer Identification No.)

                              One Meadowlands Plaza
                        East Rutherford, New Jersey 07073
                                 (201) 804-3000
          (Address and telephone number of principal executive offices)

             Cambrex Corporation 1996 Performance Stock Option Plan
                            (Full Title of the Plan)

                              Peter E. Thauer, Esq.
                      Vice President - Law and Environment,
                          General Counsel and Secretary
                               Cambrex Corporation
                              One Meadowlands Plaza
                        East Rutherford, New Jersey 07073
                                 (201) 804-3000
            (Name, address and telephone number of agent for service)

<TABLE>
<CAPTION>
                                           CALCULATION OF REGISTRATION FEE
------------------------------------------------------------------------------------------------------------------------
 Title of Securities to      Amount to be     Proposed Maximum Offering       Proposed Maximum           Amount of
     be Registered            Registered         Price Per Share (1)      Aggregate Offering Price    Registration Fee
------------------------------------------------------------------------------------------------------------------------
<S>                       <C>                           <C>                      <C>                       <C>
   Common Stock (par      21,500 shares (2)             $20.40                   $438,600.00               $46.93
 value $.10 per share)
------------------------------------------------------------------------------------------------------------------------
Total Registration Fee:                                                                                    $46.93
------------------------------------------------------------------------------------------------------------------------
</TABLE>

(1) Estimated solely for the purposes of calculating the amount of the
registration fee pursuant to Rules 457(c) of the Securities Act of 1933, as
amended, on the basis of the average of the high and low prices for shares of
common stock of Cambrex Corporation as reported on the New York Stock Exchange
on August 8, 2006 (within 5 business days before the filing date of this
Registration Statement).

(2) Represents 21,500 shares of common stock previously issued to the selling
shareholders named herein pursuant to the exercise of options granted in
accordance with the terms of the Cambrex Corporation 1996 Performance Stock
Option Plan.

<PAGE>

                                     PART I

              INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS

                                EXPLANATORY NOTE

         In accordance with Form S-8 General Instruction C and Rule 429 of the
Securities Act of 1933, as amended (the "Securities Act"), this registration
statement covers the reoffer and resale of 18,500 shares of common stock of
Cambrex Corporation ("Cambrex," the "Company," "we," "us" or "our") previously
issued to certain current and former employees named herein (the "Employees")
pursuant to the exercise of options granted in accordance with the terms of the
Cambrex Corporation 1996 Performance Stock Option Plan. This registration
statement also covers the reoffer and resale of 3,000 shares of common stock of
Cambrex previously issued to certain current and former directors named herein
(the "Directors" and together with the Employees the "Selling Shareholders")
pursuant to the terms of the Cambrex Corporation 1996 Performance Stock Option
Plan.

         This registration statement contains two parts. The first part contains
a "reoffer prospectus" prepared in accordance with Part I of Form S-3 of the
Securities Act. The second part contains information required in this
registration statement pursuant to Part II of Form S-8. This reoffer prospectus
may be used for reoffers or resales on a continuous or delayed basis in the
future of the 21,500 shares of common stock described in the previous paragraph.

                    RESTRICTED SECURITIES REOFFER PROSPECTUS

         The material which follows constitutes a prospectus prepared in
accordance with the applicable requirements of Part I of Form S-3 and General
Instruction C to Form S-8, to be used in connection with reoffers and resales of
restricted securities acquired through an employee benefit plan.

<PAGE>

                                   PROSPECTUS

                               CAMBREX CORPORATION

                          21,500 SHARES OF COMMON STOCK

This prospectus relates to 21,500 shares, in the aggregate, of common stock, par
value $.10 per share, of Cambrex Corporation which may be offered or sold from
time to time by the Selling Shareholders. The Selling Shareholders acquired the
shares pursuant to the exercise of options granted in accordance with the terms
of the Cambrex Corporation 1996 Performance Stock Option Plan.

         The price at which a Selling Shareholder may sell any shares of common
stock will be determined by the prevailing market price for such shares or
through a privately negotiated transaction. We will receive no part of the
proceeds of any sale of such shares made hereunder.

         Our common stock is traded on the New York Stock Exchange under the
symbol "CBM". On July 31, 2006 the last reported sale price of our common stock
on the New York Stock Exchange was $21.08 per share.

         The mailing address of our principal executive offices is
PlaceNameplaceOne PlaceNameMeadowlands PlaceTypePlaza, East Rutherford, New
Jersey 07073, and our telephone number is (201) 804-3000.

--------------------------------------------------------------------------------

                  INVESTING IN OUR COMMON STOCK INVOLVES RISKS.
                 PLEASE SEE "RISK FACTORS" BEGINNING ON PAGE 4.

--------------------------------------------------------------------------------

         No person has been authorized to give any information or to make any
representations, other than those contained in this prospectus in connection
with the offering made hereby, and if given or made, such information or
representations must not be relied upon as having been authorized by us, any
Selling Shareholder or any other person. Neither the delivery of this prospectus
nor any sale made hereunder shall, under any circumstances, create any
implication that information herein is correct as of any time subsequent to the
date hereof. This prospectus does not constitute an offer to sell or a
solicitation of an offer to buy any security other than the securities covered
by this prospectus, nor does it constitute an offer to or solicitation of any
person in any jurisdiction in which such offer or solicitation may not lawfully
be made.

--------------------------------------------------------------------------------

         Neither the Securities and Exchange Commission (the "Commission") nor
any state securities commission has approved or disapproved of these securities
or determined if this prospectus is truthful or complete. Any representation to
the contrary is a criminal offense.

                 The date of this prospectus is August 11, 2006.

                                       3

<PAGE>

                                TABLE OF CONTENTS

                                                                            PAGE

CAMBREX CORPORATION..........................................................4
RISK FACTORS.................................................................4
USE OF PROCEEDS..............................................................13
DILUTION.....................................................................13
SELLING SHAREHOLDERS.........................................................14
PLAN OF DISTRIBUTION.........................................................14
EXPERTS......................................................................15
WHERE YOU CAN FIND MORE INFORMATION..........................................15
INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE..............................16

                               CAMBREX CORPORATION

         Cambrex is a leading innovative supplier of human health and
biosciences products to the life sciences industry. Cambrex serves the
innovative and generic pharmaceutical markets and the bioresearch,
biotherapeutic and biopharmaceutical markets, including universities, research
organizations and the government.

                                  RISK FACTORS

         You should carefully consider the following factors and other
information in this prospectus and in our annual reports on Forms 10-K when you
evaluate our business. If any of the following risks occur, the Company's
business, financial condition, operating results and cash flows could be
materially adversely effected. The risks and uncertainties described below are
not the only ones the Company faces. Additionally, risks and uncertainties not
presently known to the Company or that it currently deems immaterial also may
impair its business, financial condition, operating results and cash flows in
the future.

THE COMPANY'S ANALYSIS, CONSIDERATION AND IMPLEMENTATION OF STRATEGIC
ALTERNATIVES MAY MATERIALLY ADVERSELY AFFECT OUR BUSINESS, FINANCIAL CONDITION
OR RESULTS OF OPERATIONS.

         As previously announced, the Company has retained Bear Stearns & Co.,
Inc. to act as advisors to our board of directors in the analysis and
consideration of strategic alternatives to maximize shareholder value, including
the potential sale of certain assets. There are several strategic alternatives
that may be pursued.

         However, we are presently unable to assess what impact any particular
strategic alternative will have on our stock price if accomplished, and our
consideration and implementation of strategic alternatives may not be
successful. Uncertainties and risks relating to our analysis and consideration
of strategic alternatives include but are not limited to:

         -  the analysis and consideration of strategic alternatives may disrupt
            operations and distract members of management and other employees,
            which could adversely affect our results of operations;

         -  the process of exploring strategic alternatives may be more time
            consuming and expensive than currently anticipated;

                                       4

<PAGE>
         -  we may not be able to successfully achieve the benefits of the
            strategic alternative undertaken; and

         -  perceived uncertainties as to the future direction of the Company
            may result in the loss of employees, customers, clients or business
            partners.

WE MAY PURSUE TRANSACTIONS THAT MAY CAUSE US TO EXPERIENCE SIGNIFICANT CHARGES
TO EARNINGS THAT MAY ADVERSELY AFFECT OUR STOCK PRICE AND FINANCIAL CONDITION.

         We regularly review potential transactions related to technologies,
products, product rights and businesses complementary to our business. These
transactions could include mergers, acquisitions, divestitures, strategic
alliances or licensing agreements. In the future, we may choose to enter into
these transactions at any time. As a result of acquiring businesses or entering
into other significant transactions, we have previously experienced, and may
continue to experience, significant charges to earnings for merger and related
expenses that may include transaction costs, closure costs or costs related to
the write-off of acquired in-process research and development. These costs may
also include substantial fees for investment bankers, attorneys, accountants,
financial printing costs, severance and other closure costs associated with the
elimination of duplicate or discontinued products, employees, operations and
facilities. Although we do not expect these charges to have a material adverse
effect upon our overall financial condition, these charges could have a material
impact on our results of operations for particular quarters or years and they
could possibly have an adverse impact upon the market price of our common stock.

IF WE MAKE ACQUISITIONS, WE MAY EXPERIENCE DIFFICULTY INTEGRATING THE BUSINESSES
WHICH COULD HAVE A MATERIAL ADVERSE EFFECT ON OUR BUSINESS, FINANCIAL CONDITION
AND RESULTS OF OPERATIONS.

         An important part of our business growth strategy is to acquire
products, product lines, technologies and capabilities, including through the
acquisition of businesses and to enhance the Company's position in its niche
markets. We continually explore and conduct discussions with many third parties
regarding possible acquisitions. Our ability to continue to achieve our goals
may depend upon our ability to effectively integrate such businesses, to achieve
cost efficiencies and to manage these businesses as part of our company.
However, we may experience difficulty integrating the merged companies which
could have a material adverse effect on the operating results or financial
condition of the combined company. As a result of uncertainty following an
acquisition and during the integration process, we could experience disruption
in our business or employee base. There is also a risk that key employees of the
combined company may seek employment elsewhere, including with competitors, or
that valued employees may be lost upon the elimination of duplicate functions.
If we are not able to successfully blend our products and technologies with the
acquired business to create the advantages the acquisition was intended to
create, it may effect our results of operations, our ability to develop and
introduce new products and the market price of our common stock. Furthermore,
there may be overlap between our products, services or customers, and the
combined company may create conflicts in relationships or other commitments
detrimental to the integrated businesses.

IF WE FAIL TO IMPROVE THE OPERATIONS OF FUTURE ACQUIRED BUSINESSES, WE MAY BE
UNABLE TO ACHIEVE OUR GROWTH STRATEGY.

         Some of the businesses we have acquired or will acquire had or may have
significantly lower operating margins than we do and/or operating losses prior
to the time we acquired them. In the past, we have occasionally experienced
temporary delays in improving the operating margins of these acquired

                                       5

<PAGE>

businesses. In the future, if we are unable to improve the operating margins of
acquired businesses or operate them profitably, we may be unable to achieve our
growth strategy.

PHARMACEUTICAL, BIOPHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES MAY DISCONTINUE OR
DECREASE THEIR USAGE OF OUR SERVICES.

         We depend on pharmaceutical, biopharmaceutical and biotechnology
companies that use our services for a large portion of our revenues. Although
there has been a trend among these companies to outsource therapeutic production
functions, this trend may not continue. We have observed increasing pressure on
the part of our customers to reduce spending, including the use of our services,
as a result of negative economic trends generally and in the pharmaceutical
industry. If these companies discontinue or decrease their usage of our
services, including as a result of an economic slowdown in the overall
country-regionplaceUnited States or foreign economies, our revenues and earnings
could be lower than we expect and our revenues may decrease or not grow at
historical rates.

COMPETITION IN THE LIFE SCIENCES RESEARCH MARKET, AND/OR A REDUCTION IN DEMAND
FOR OUR PRODUCTS, COULD REDUCE SALES.

         The markets for our products are competitive and price sensitive. Other
life science suppliers have significant financial, operational, sales and
marketing resources, and experience in research and development. These and other
companies may have developed or could in the future develop new technologies
that would compete with our products or render our products obsolete. If a
competitor develops superior technology or cost-effective alternatives to our
products or services, our business, operating results, and financial condition
could be seriously harmed. In addition, demand for our products may weaken due
to reduction in research and development budgets, loss of distributors or other
factors, which would have an adverse effect on our financial condition.

         The markets for certain of our products are also subject to specific
competitive risks and can be highly price competitive. Our competitors have
competed in the past by lowering prices on certain products. Our competitors may
lower prices on these or other products in the future and we may, in certain
cases, respond by lowering our prices. This would reduce revenues and profits.
Conversely, failure to anticipate and respond to price competition may hurt our
market share.

         We believe that customers in our markets display loyalty to their
initial supplier of a particular product. Therefore, it may be difficult to
generate sales to potential customers who have purchased products from
competitors. To the extent we are unable to be the first to develop and supply
new products, our competitive position may suffer.

OUR FAILURE TO OBTAIN NEW CONTRACTS OR RENEWED CONTRACTS OR CANCELLATION OF
EXISTING CONTRACTS MAY ADVERSELY EFFECT OUR BUSINESS, FINANCIAL CONDITION AND
RESULTS OF OPERATIONS AND MAKE OUR REVENUE DIFFICULT TO PREDICT.

         Many of our contracts are short-term in duration. As a result, we must
continually replace our contracts with new contracts to sustain our revenue. In
addition, many of our long-term contracts may be cancelled or delayed by clients
for any reason upon notice. Contracts may be terminated for a variety of
reasons, including termination of product development, failure of products to
satisfy safety requirements, unexpected or undesired results from use of the
product or the client's decision to forego a particular study. The Company
currently has a long-term sales contract within the Human Health segment that
accounts for more than 10% of segment sales that is scheduled to expire at the
end of 2008. There is no guarantee that this contract will be renewed. Our
failure to obtain new contracts or renew contracts or the

                                       6

<PAGE>

cancellation or delay of existing contracts could have a material adverse effect
on our business, financial condition and results of operations.

         Furthermore, because our revenue is primarily generated on a
contract-by-contract or purchase order basis, our revenue is difficult to
predict and contributes to the variability of our financial results from period
to period. In addition, we do not believe that a backlog of contracts is a
meaningful indicator of our future revenue because much of our revenue is
resulting from short-term contracts or purchase orders and these contracts can
often be terminated for many reasons.

THE BIOPHARMA BUSINESS SEGMENT HAS EXPERIENCED AND MAY CONTINUE TO EXPERIENCE
SIGNIFICANT VOLATILITY IN PROFITABILITY AND THERE ARE NO ASSURANCES THAT IT WILL
RETURN TO ITS HISTORIC PROFITABILITY LEVEL.

         The Company's Biopharma segment provides process development and
manufacturing services on a contract basis to biopharmaceutical companies. This
business has a very high fixed cost structure and its customers are often
dependent on the availability of funding and pursuing drugs that are in earlier
stages of clinical trials, and thus have high failure rates. Losses of one or
more customers can result in significant swings in profitability from quarter to
quarter and year to year. Returning to historic profitability levels is
dependent on the Company generating significant additional revenues from
existing and new customers, which can not be assured.

THE COMPANY COULD BE SUBJECT TO ADDITIONAL IMPAIRMENT CHARGES IN THE FUTURE.

         During 2004 and 2005, the Company recorded impairment charges to reduce
goodwill and long-lived assets in 2005. The Company may be subject to additional
impairment charges if the business units do not perform at or near projected
levels in the future. Should the profit forecast for these businesses be revised
significantly downward, the Company may incur additional impairment charges.

OUR OPERATING RESULTS MAY UNEXPECTEDLY FLUCTUATE IN FUTURE PERIODS.

         The Company's revenue and operating results have fluctuated, and could
continue to fluctuate, on a quarterly basis. The operating results for a
particular quarter may be lower than expected as a result of a number of
factors, including the timing of contracts; the delay or cancellation of a
contract; the mix of services provided; seasonal slowdowns in different parts of
the world; the timing of start-up expenses for new services and facilities; and
changes in government regulations. Because a high percentage of the Company's
costs are relatively fixed in the short term (such as the cost of maintaining
facilities and compensating employees), any one of these factors could have a
significant impact on the Company's quarterly results. In some quarters, the
Company's revenue and operating results may fall below the expectations of
securities analysts and investors due to any of the factors described above. In
such event, the trading price of the Company's common stock would likely
decline, even if the decline in revenue did not have any long-term adverse
implications for the Company's business.

OUR MARKET SHARE DEPENDS ON NEW PRODUCT INTRODUCTIONS AND ACCEPTANCE.

         Rapid technological change and frequent new product introductions are
typical of the market for certain of our products and services. Our future
success will depend in part on continuous, timely development and introduction
of new products that address evolving market requirements and are attractive to
customers. We believe successful new product introductions provide a significant
competitive advantage because customers make an investment of time in selecting
and learning to use a new product, and are reluctant to switch thereafter. We
spend significant resources on internal research and development, as well as on
technology development elsewhere to support our effort to develop and

                                       7

<PAGE>

introduce new products. To the extent that we fail to introduce new and
innovative products, we could fail to obtain an adequate return on these
investments and could lose market share to our competitors, which may be
difficult to regain. An inability, for technological or other reasons, to
develop successfully and introduce new products could reduce our growth rate or
otherwise damage our business.

         In the past, we have experienced, and may experience in the future,
delays in the development and introduction of products. We cannot be assured
that we will keep pace with the rapid change in life sciences research, or that
our new products will adequately meet the requirements of the marketplace or
achieve market acceptance. Some of the factors effecting market acceptance of
our products include:

         -  availability, quality and price as compared to competitive products;

         -  the functionality of new and existing products;

         -  the timing of introduction of our products as compared to
            competitive products;

         -  scientists' and customers' opinions of the product's utility and our
            ability to incorporate their feedback into future products;

         -  general trends in life sciences research.

         The expenses or losses associated with unsuccessful product development
activities or lack of market acceptance of our new products could adversely
affect our business, financial condition and results of operations.

FAILURE TO OBTAIN PRODUCTS AND COMPONENTS FROM THIRD-PARTY MANUFACTURERS COULD
AFFECT OUR ABILITY TO MANUFACTURE AND DELIVER OUR PRODUCTS.

         We rely on third-party manufacturers to supply many of our raw
materials, product components, and in some cases, entire products. In addition,
we have a single source for supplies of some raw materials and components to our
products. Manufacturing problems may occur with these and other outside sources.
If such problems occur, we cannot ensure that we will be able to manufacture our
products profitably or on time.

ANY SIGNIFICANT REDUCTION IN GOVERNMENT REGULATION OF THE DRUG DEVELOPMENT
PROCESS COULD HAVE A MATERIAL ADVERSE EFFECT ON OUR BUSINESS, FINANCIAL
CONDITION AND RESULTS OF OPERATIONS.

         The design, development, testing, manufacturing and marketing of
biotechnology and pharmaceutical products are subject to extensive regulation by
governmental authorities, including the U.S. Food and Drug Administration
("FDA") and comparable regulatory authorities in other countries. The Company's
business depends in part on strict government regulation of the drug development
process. Legislation may be introduced and enacted from time to time to modify
regulations administered by the FDA and governing the drug approval process. Any
significant reduction in the scope of regulatory requirements or the
introduction of simplified drug approval procedures could have a material
adverse effect on the Company's business, financial condition and results of
operations.

VIOLATIONS OF CGMP AND OTHER GOVERNMENT REGULATIONS COULD HAVE A MATERIAL
ADVERSE EFFECT ON OUR BUSINESS, FINANCIAL CONDITION AND RESULTS OF OPERATIONS.

                                       8

<PAGE>

         All facilities and manufacturing techniques used for manufacturing of
products for clinical use or for commercial sale in the
country-regionplaceUnited States must be operated in conformity with current
Good Manufacturing Practices ("cGMP") regulations as required by the FDA. The
Company's facilities are subject to scheduled periodic regulatory and customer
inspections to ensure compliance with cGMP and other requirements applicable to
such products. A finding that the Company had materially violated these
requirements could result in regulatory sanctions, the loss of a customer
contract, the disqualification of data for client submissions to regulatory
authorities and/or a mandated closing of the Company's facilities. Any such
material violations would have a material adverse effect on the Company's
business, financial condition and results of operations.

         The Commission is currently conducting an investigation into the
Company's inter-company accounting procedures from the period 1997-2001. The
investigation began during the first half of 2003 after the Company voluntarily
disclosed certain matters related to inter-company accounts for the five-year
period ending December 31, 2001 that resulted in the restatement of the
Company's financial statements for those years. The Company is fully cooperating
with the SEC and does not expect further revisions to its historical financial
statements relating to these issues. This investigation could lead to an adverse
outcome and adversely effect our business, financial condition, results of
operations and cash flows.

LITIGATION MAY HARM OUR BUSINESS OR OTHERWISE NEGATIVELY IMPACT OUR MANAGEMENT
AND FINANCIAL RESOURCES.

         Substantial, complex or extended litigation could cause the Company to
incur large expenditures and distract our management. For example, lawsuits by
employees, stockholders, counterparties to acquisition and divestiture
contracts, collaborators, distributors, customers, or end-users of our products
or services could be very costly and substantially disrupt our business.
Disputes from time to time with such companies or individuals are not uncommon,
and we cannot assure you that we will always be able to resolve such disputes
out of court or on terms favorable to the Company.

         The Company is involved in a number of lawsuits including a class
action lawsuit filed against Cambrex and certain current Company officers
alleging the failure to disclose in a timely fashion the restatement of results
for the five-year period ending December 31, 2001 as discussed in the risk
factor above, as well as the loss of a significant contract at our Baltimore
facility. If this matter, or any of the Company's other lawsuits, is resolved in
an unfavorable manner, they could have a material adverse effect on the
operating results and cash flows in future periods.

LOSS OF KEY PERSONNEL COULD HURT OUR BUSINESS.

         The Company depends on a number of key executives. The loss of services
of any of the Company's key executives could have a material adverse effect on
the Company's business.

         The Company also depends on its ability to attract and retain qualified
scientific and technical employees. There can be no assurance the Company will
be able to retain its existing scientific and technical employees, or to attract
and retain additional qualified employees. The Company's inability to attract
and retain qualified scientific and technical employees would have a material
adverse effect on the Company's business, financial condition and results of
operations.

POTENTIAL PRODUCT LIABILITY CLAIMS, ERRORS AND OMISSIONS CLAIMS IN CONNECTION
WITH SERVICES WE PERFORM AND POTENTIAL LIABILITY UNDER INDEMNIFICATION
AGREEMENTS BETWEEN US AND OUR OFFICERS AND DIRECTORS COULD ADVERSELY EFFECT OUR
EARNINGS AND FINANCIAL CONDITION.

                                       9

<PAGE>

         The Company manufactures products intended for use by the public. In
addition, the Company's services include the manufacture of pharmaceutical and
biologic products to be tested in human clinical trials and for consumption by
humans. These activities could expose the Company to risk of liability for
personal injury or death to persons using such products, although the Company
does not presently market or sell the products to end users. The Company seeks
to reduce its potential liability through measures such as contractual
indemnification provisions with clients (the scope of which may vary from
client-to-client, and the performances of which are not secured), exclusion of
services requiring diagnostic or other medical services, and insurance
maintained by clients. The Company could be materially and adversely effected if
it were required to pay damages or incur defense costs in connection with a
claim that is outside the scope of the indemnification agreements, if the
indemnity, although applicable, is not performed in accordance with its terms or
if the Company's liability exceeds the amount of applicable insurance or
indemnity. In addition, the Company could be held liable for errors and
omissions in connection with the services it performs. The Company currently
maintains product liability and errors and omissions insurance with respect to
these risks. There can be no assurance, however, that the Company's insurance
coverage will be adequate or that insurance coverage will continue to be
available on terms acceptable to the Company.

         The Company also indemnifies its officers and directors for certain
events or occurrences while the officer or director is, or was serving, at the
Company's request in such capacity. The maximum potential amount of future
payments the Company could be required to make under these indemnification
agreements is unlimited; however, the Company has a "Director and Officer"
insurance policy that covers a portion of any potential exposure. The Company
could be materially and adversely effected if it were required to pay damages or
incur legal costs in connection with a claim above its insurance limits.

ASSESSMENTS BY VARIOUS TAX AUTHORITIES MAY BE MATERIALLY DIFFERENT THAN WE HAVE
PROVIDED FOR AND WE MAY EXPERIENCE SIGNIFICANT VOLATILITY IN OUR ANNUAL AND
QUARTERLY EFFECTIVE TAX RATE.

         As a matter of course, the Company is regularly audited by federal,
state, and foreign tax authorities. From time to time, these audits result in
proposed assessments. While the Company believes that it has adequately provided
for any such assessments, future settlements may be materially different than we
have provided for and negatively effect our earnings.

         Since 2003, the geographic mix of income has resulted in the
recording of a valuation allowance against all net domestic deferred tax assets.
Going forward, until such time as the Company's domestic profitability is
restored and considered by management to be sustainable for the foreseeable
future, the Company will not record the income tax benefit or expense for
domestic pre-tax losses and income respectively, and as such may experience
significant volatility in its effective tax rate.

WE HAVE A SIGNIFICANT AMOUNT OF DEBT THAT COULD ADVERSELY EFFECT OUR FINANCIAL
CONDITION.

         The Company has a $277,500 revolving credit facility of which $81,943
was outstanding at December 31, 2005. In addition, the Company had privately
placed notes of $100,000 (repaid in January 2006 by drawing down our existing
revolving credit facility).

         Even if we are able to meet our debt service obligations, the amount of
debt we have could adversely effect us in a number of ways, including:

                                       10

<PAGE>

         -  limiting our ability to obtain any necessary financing in the future
            for working capital, capital expenditures, debt service
            requirements, or other purposes;

         -  limiting our flexibility in planning for, or reacting to, changes in
            our business;

         -  placing us at a competitive disadvantage relative to our competitors
            who have lower levels of debt;

         -  making us more vulnerable to a downturn in our business or the
            economy generally;

         -  requiring us to use a substantial portion of our cash to pay
            principal and interest on our debt, instead of contributing those
            funds to other purposes such as working capital and capital
            expenditures.

INTERNATIONAL UNREST OR FOREIGN CURRENCY FLUCTUATIONS COULD ADVERSELY EFFECT OUR
RESULTS.

         Our international revenues, which include revenues from our non-U.S.
subsidiaries and export sales from the country-regionplaceU.S., represented 62%
of our product revenues in 2005 and 61% of our product revenues in 2004. We
expect that international revenues will continue to account for a significant
percentage of our revenues for the foreseeable future.

         There are a number of risks arising from our international business,
including:

         -  foreign currencies we receive for sales outside the
            country-regionplaceU.S. could be subject to unfavorable exchange
            rates with the U.S. dollar and reduce the amount of revenue that we
            recognize;

         -  the possibility that unfriendly nations or groups could boycott our
            products;

         -  general economic and political conditions in the markets in which we
            operate;

         -  potential increased costs associated with overlapping tax
            structures;

         -  more limited protection for intellectual property rights in some
            countries;

         -  unexpected changes in regulatory requirements;

         -  the difficulties of compliance with a wide variety of foreign laws
            and regulations;

         -  longer accounts receivable cycles in certain foreign countries; and

         -  import and export licensing requirements.

         A significant portion of our business is conducted in currencies other
than the U.S. dollar, which is our reporting currency. We recognize foreign
currency gains or losses arising from our operations in the period incurred. As
a result, currency fluctuations between the U.S. dollar and the currencies in
which we do business have caused and will continue to cause foreign currency
transaction gains and losses. We cannot predict the effects of exchange rate
fluctuations upon our future operating results because of the number of
currencies involved, the variability of currency exposures, and the potential
volatility of currency exchange rates. We engage in limited foreign exchange
hedging transactions to manage our foreign currency exposure, but our strategies
are short-term in nature and may not adequately protect our operating results
from the full effects of exchange rate fluctuations.

                                       11

<PAGE>

THE MARKET PRICE OF OUR STOCK COULD BE VOLATILE.

         The market price of our common stock has been subject to volatility
and, in the future, the market price of our common stock may fluctuate
substantially due to a variety of factors, including:

         -  quarterly fluctuations in our operating income and earnings per
            share results;

         -  technological innovations or new product introductions by us or our
            competitors;

         -  economic conditions;

         -  disputes concerning patents or proprietary rights;

         -  changes in earnings estimates and market growth rate projections by
            market research analysts;

         -  sales of common stock by existing holders;

         -  loss of key personnel; and

         -  securities class actions or other litigation.

         The market price for our common stock may also be effected by our
ability to meet analysts' expectations. Any failure to meet such expectations,
even slightly, could have an adverse effect on the market price of our common
stock. In addition, the stock market is subject to extreme price and volume
fluctuations. This volatility has had a significant effect on the market prices
of securities issued by many companies for reasons unrelated to the operating
performance of these companies.

INCIDENTS RELATED TO HAZARDOUS MATERIALS COULD ADVERSELY EFFECT OUR BUSINESS.

         Portions of our operations require the controlled use of hazardous
materials. Although we are diligent in designing and implementing safety
procedures to comply with the standards prescribed by federal, state, and local
regulations, the risk of accidental contamination of property or injury to
individuals from these materials cannot be completely eliminated. In the event
of such an incident, we could be liable for any damages that result, which could
adversely effect our business.

         Additionally, any incident could partially or completely shut down our
research and manufacturing facilities and operations.

         We generate waste that must be transported to approved storage,
treatment and disposal facilities. The transportation and disposal of such waste
are required to meet applicable state and federal statutes and regulations. The
storage, treatment and disposal of such waste potentially exposes us to
environmental liability if, in the future, such transportation and disposal are
deemed to have violated such statues and/or regulations or if the storage,
treatment and disposal facilities are inadequate and are proved to have damaged
the environment.

         The Company is also party to several environmental remediation
investigations and cleanups and, along with other companies, has been named a
"potential responsible party" for certain waste disposal sites. The Company has
also retained the liabilities with respect to certain pre-closing environmental
matters associated with the sale of the Rutherford Chemicals business. After
reviewing information

                                       12

<PAGE>

currently available, management believes any amount paid in excess of accrued
liabilities will not have a material effect on its business, financial condition
or results of operations. However, these matters, if resolved in a manner
different from the estimates, could have a material adverse effect on the
financial condition, operating results and cash flows when resolved in future
reporting periods.

THE POSSIBILITY WE WILL BE UNABLE TO PROTECT OUR TECHNOLOGIES COULD EFFECT OUR
ABILITY TO COMPETE.

         Our success depends to a significant degree upon our ability to develop
proprietary products and technologies. However, we cannot be assured that
patents will be granted on any of our patent applications. We also cannot be
assured that the scope of any of our issued patents will be sufficiently broad
to offer meaningful protection. We only have patents issued in selected
countries. Therefore, third parties can make, use, and sell products covered by
our patents in any country in which we do not have patent protection. In
addition, our issued patents or patents we license could be successfully
challenged, invalidated or circumvented so that our patent rights would not
create an effective competitive barrier. We provide our customers the right to
use our products under label licenses that are for research purposes only. These
licenses could be contested, and we cannot be assured that we would either be
aware of an unauthorized use or be able to enforce the restrictions in a
cost-effective manner.

         If a third party claimed an intellectual property right to technology
we use, we may need to discontinue an important product or product line, alter
our products and processes, defend our right to use such technology in court or
pay license fees. Although we may, under these circumstances, attempt to obtain
a license to such intellectual property, we may not be able to do so on
favorable terms, or at all. Additionally, if our products are found to infringe
on a third party's intellectual property, we may be required to pay damages for
past infringement, and lose the ability to sell certain products or receive
licensing revenues.

COMPLIANCE WITH CHANGING REGULATION OF CORPORATE GOVERNANCE AND PUBLIC
DISCLOSURE MAY RESULT IN ADDITIONAL EXPENSE.

         Changing laws, regulations and standards relating to corporate
governance and public disclosure, including the Sarbanes-Oxley Act of 2002, are
creating uncertainty for companies. These new or changed laws and standards are
subject to multiple interpretations, in many cases due to their lack of
specification. As a result, their application in practice may evolve over time
as new guidance is provided by regulatory and governing bodies which could
result in higher costs necessitated by revisions to disclosures and governance
practices. We are committed to maintaining high standards of corporate
governance and public disclosure. As a result of the efforts to comply with the
evolving laws and regulations increased general and administrative expenses have
been experienced and are likely to continue. In particular, our efforts to
comply with Section 404 of the Sarbanes-Oxley Act of 2002, and the related
assessments have required commitment of significant internal and external
financial and operational resources.

                                 USE OF PROCEEDS

         We will not receive any of the proceeds from the sale of any shares of
our common stock by the Selling Shareholders pursuant to this reoffer
prospectus. All such proceeds, net of brokerage commissions, if any, will be
received by the Selling Shareholders.

                                    DILUTION

         Because any Selling Shareholders who offer and sell their shares of
common stock covered by this prospectus may do so at various times, at prices
and at terms then prevailing or at prices related to the then current market
price, or in negotiated transactions, we have not included in this prospectus

                                       13

<PAGE>

information about the dilution (if any) to the public arising from these sales.

                              SELLING SHAREHOLDERS

         The shares of common stock to which this prospectus relates may be
offered or sold from time to time by the Selling Shareholders.

         The following table sets forth certain information as to the beneficial
ownership of Cambrex's common stock as of August 4, 2006 for each Selling
Shareholder (a current or former employee or director of the Company, as
indicated below).

<TABLE>
<CAPTION>
--------------------------------------------------------------------------------------------------------------------
                                                                                                PERCENTAGE OF SHARES
                             NUMBER OF SHARES      MAXIMUM NUMBER OF       NUMBER OF SHARES      BENEFICIALLY OWNED
     NAME OF SELLING        BENEFICIALLY OWNED   SHARES ELIGIBLE TO BE    BENEFICIALLY OWNED     AFTER THE OFFERING
     SHAREHOLDER (1)         PRIOR TO OFFERING         OFFERED (2)         AFTER THE OFFERING             (7)
--------------------------------------------------------------------------------------------------------------------
<S>                             <C>                    <C>                      <C>                      <C>
Stephen Colasuonno (4)             500                   500                         0                    *
Dave Goodman (4)                 3,833                 3,000                       833                    *
George Goodman (5)               7,816                 1,500                     6,316                    *
Leon Hendrix Jr. (6)            19,302                 1,500                    17,802                    *
Theresa Hernan (4)               5,004                 4,500                       504                    *
Carl Johansson (4)               4,500                 4,500                         0                    *
Michael Lafond (3)               5,689                 4,500                     1,189                    *
Ulf Sjoestrand (4)               1,000                 1,000                         0                    *
Roop Kumar (3)                     500                   500                         0                    *
--------------------------------------------------------------------------------------------------------------------
</TABLE>

* Less than 1%.

(1)   Each Selling Shareholder received shares of common stock pursuant to the
      exercise on April 25, 2006 of options granted in accordance with the terms
      of the Cambrex Corporation 1996 Performance Stock Option Plan, except for
      Roop Kumar who exercised on April 24, 2006.

(2)   Only the shares acquired in connection with the Cambrex Corporation 1996
      Performance Stock Option Plan described in note (1) are eligible to be
      offered under this prospectus.

(3)   Former employee.

(4)   Current employee.

(5)   Former director.

(6)   Current director.

(7)   For the purpose of this table, the percent of issued and outstanding
      shares of common stock held by each Selling Shareholder has been
      calculated on the basis of 26,753,156 shares of common stock issued and
      outstanding (excluding treasury shares) on August 8, 2006.

                              PLAN OF DISTRIBUTION

         We are registering the shares of common stock covered by this
prospectus for the Selling Shareholders or their pledgees, donees, transferees
or other successors-in-interest as a gift, partnership distribution or other
non-sale-related-transfer after the date of this prospectus, who may sell the
shares from time to time. The Selling Shareholders will act independently of us
in making decisions with respect to the timing, manner and size of each sale.
The sales may be made on one or more exchanges or otherwise, at prices and at
terms then prevailing or at prices related to the then current market price, or
in negotiated transactions. The Selling Shareholders may effect such
transactions by selling the shares to or through broker-dealers or directly to
purchasers (in the event of a private sale). The shares may be sold by one or
more of, or a combination of, the following:

                                       14

<PAGE>

         -  a block trade in which the broker-dealer so engaged will attempt to
            sell the shares as agent but may position and resell a portion of
            the block as principal to facilitate the transaction;

         -  purchases by a broker-dealer as principal and resale by such
            broker-dealer for its account pursuant to this prospectus;

         -  ordinary brokerage transactions and transactions in which the broker
            solicits purchasers; and

         -  in privately negotiated transactions.

         Certain Selling Shareholders may enter into hedging transactions with
broker-dealers in connection with distributions of the shares or otherwise. In
such transactions, broker-dealers may engage in short sales of the shares in the
course of hedging the positions they assume with certain Selling Shareholders.
Certain Selling Shareholders may also sell the shares short and redeliver the
shares to close out such short positions. Such Selling Shareholders may enter
into option or other transactions with broker-dealers which require the delivery
to the broker-dealer of the shares. The broker-dealer may then resell or
otherwise transfer such shares pursuant to this prospectus.

         Certain Selling Shareholders also may loan or pledge the shares to a
broker-dealer. The broker-dealer may sell the shares so loaned, or upon a
default the broker-dealer may sell the pledged shares, pursuant to this
prospectus.

         Broker-dealers or agents may receive compensation in the form of
commissions, discounts or concessions from Selling Shareholders. Broker-dealers
or agents may also receive compensation from the purchasers of the shares for
whom they act as agents or to whom they sell as principals, or both. In such
cases, usual and customary brokerage fees will be paid by the Selling
Shareholders. Broker-dealers or agents and any other participating
broker-dealers or the Selling Shareholders may be deemed to be "underwriters"
within the meaning of Section 2(11) of the Securities Act in connection with
sales of the shares. Accordingly, any such commission, discount or concession
received by them and any profit on the resale of the shares purchased by them
may be deemed to be underwriting discounts or commissions under the Securities
Act. Because Selling Shareholders may be deemed to be "underwriters" within the
meaning of Section 2(11) of the Securities Act, the Selling Shareholders will be
subject to the prospectus delivery requirements of the Securities Act. In
addition, any securities covered by this prospectus which qualify for sale
pursuant to Rule 144 promulgated under the Securities Act may be sold under Rule
144 rather than pursuant to this prospectus. There is no underwriter or
coordinating broker acting in connection with the proposed sale of the shares by
the Selling Shareholders.

         We will bear all costs, expenses and fees in connection with the
registration of the shares. The Selling Shareholders will bear all commissions
and discounts, if any, attributable to the sales of the shares. The Selling
Shareholders may agree to indemnify any broker-dealer or agent that participates
in transactions involving sales of the shares against certain liabilities,
including liabilities arising under the Securities Act.

                                       15

<PAGE>

                                     EXPERTS

         The financial statements and management's assessment of the
effectiveness of internal control over financial reporting (which is included in
Management's Report on the Internal Control over Financial Reporting)
incorporated in this Prospectus by reference to the Annual Report on Form 10-K
for the year ended December 31, 2005 have been so incorporated in reliance on
the report (which contains an adverse opinion on the effectiveness of internal
control over financial reporting) of PricewaterhouseCoopers LLP, an independent
registered public accounting firm, given on the authority of said firm as
experts in auditing and accounting.


                       WHERE YOU CAN FIND MORE INFORMATION

         We file annual, quarterly and special reports, proxy statements and
other information with the Securities and Exchange Commission. You may read and
copy any of the information on file with the Commission at the Commission's
Public Reference Room at address Street 450 Fifth Street, N.W., Room 1024,
Washington, State D.C. Postal Code 20549. Please call the Commission at
1-800-SEC-0330 for further information on the Public Reference Room. In
addition, the Commission maintains an Internet site at http://www.sec.gov that
contains reports, proxy and information statements, and other information
regarding issuers that file electronically with the Commission. We began filing
documents with the Commission electronically on March 22, 1994. Our filings with
the Commission are also available to the public from commercial document
retrieval services. Some of our filings are available at http://www.cambrex.com.

         Our common stock is listed on the New York Stock Exchange. Reports and
other information concerning Cambrex may be inspected at the offices of the New
York Stock Exchange, address Street 20 Broad Street, City New York, State New
York Postal Code 10005.

         We filed a registration statement on Form S-8 to register with the
Commission the shares of common stock offered by this prospectus. This document
is part of that registration statement and constitutes a prospectus of Cambrex.
As permitted by Commission rules, this document does not contain all the
information you can find in the registration statement or exhibits to the
registration statement.

                 INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

         The Commission allows us to incorporate by reference information into
this document, which means that we can disclose important information to you by
referring you to another document filed separately with the Commission. The
information incorporated by reference is deemed to be part of this document,
except for any information superseded by information in this document or a
document subsequently filed by us. This document incorporates by reference the
documents set forth below that we have previously filed with the Commission.
These documents contain important information about us and our financial
performance.

(a)  Annual Report on Form 10-K         Year ended December 31, 2005

(b)  Quarterly Reports on Form 10-Q     Quarter Ended March 31, 2006 and
                                        June 30, 2006

(c)  Current Reports on Form 8-K (to    Dated January 4, 2006, February 3, 2006,
     the extent not furnished)          February 7, 2006, March 20, 2006,
                                        May 3, 2006, and August 4, 2006

(d)  The description of the shares of common stock of Cambrex contained in the
     registration statement filed pursuant to Section 12 of the Securities
     Exchange Act of 1934, as amended ("Exchange Act"),

                                       16

<PAGE>

      including any amendment or report filed for the purpose of updating such
      description.

(e)  All documents subsequently filed by us pursuant to Section 13(a), 13(c), 14
     or 15(d) of the Exchange Act, prior to the termination of the offering,
     shall be deemed to be incorporated by reference into this prospectus.

         Copies of these filings, excluding all exhibits unless an exhibit has
been specifically incorporated by reference in this document, are available from
us, at no cost, by writing or telephoning us at:

         Cambrex Corporation
         One PlaceNameplaceMeadowlands PlaceTypePlaza
         East Rutherford, StateNew Jersey PostalCode07073
         Tel: (201) 804-3000
         Attn: Secretary

         You should rely only on the information incorporated by reference or
provided in this prospectus or any prospectus supplement. We have authorized no
one to provide you with different information. You should not assume that the
information in this prospectus or any prospectus supplement is accurate as of
any date other than the date on the front of that document, regardless of the
time of delivery of this prospectus or of any sale of shares of common stock.

                                       17

<PAGE>

                                     PART II
                           INFORMATION REQUIRED IN THE
                             REGISTRATION STATEMENT

ITEM 3. INCORPORATION OF DOCUMENTS BY REFERENCE.

         The following documents or extracts of documents, which previously have
been filed by Cambrex with the Commission, are incorporated herein by reference
and made a part hereof:

(a)  Annual Report on Form 10-K         Year ended December 31, 2005

(b)  Quarterly Reports on Form 10-Q     Quarter Ended March 31, 2006 and
                                        June 30, 2006

(c)  Current Reports on Form 8-K (to    Dated January 4, 2006, February 3, 2006,
     the extent not furnished)          February 7, 2006, March 20, 2006,
                                        May 3, 2006 and August 4, 2006

(d)  The description of the shares of common stock of Cambrex contained in the
     registration statement filed pursuant to Section 12 of the Exchange Act,
     including any amendment or report filed for the purpose of updating such
     description.

(e)  All other reports filed by us pursuant to Section 13(a) or 15(d) of the
     Exchange Act since the end of the fiscal year covered by the Annual Report
     referred to in (a) above.

(f)  All documents filed by us pursuant to Sections 13(a), 13(c), 14 or 15(d) of
     the Exchange Act, after the date hereof and prior to the filing of a
     post-effective amendment which indicates that all securities covered hereby
     have been sold or which deregisters all securities covered hereby then
     remaining unsold, such documents to form a part hereof, commencing on the
     respective dates on which the documents are filed.

         For purposes of this registration statement, any document or any
statement deemed to be incorporated by reference herein or contained in an
incorporated document shall be deemed to be modified or superseded for purposes
hereof to the extent that a statement contained herein or in any other
subsequently filed incorporated document modifies or supersedes such statement.
Any such statement so modified or superseded shall not be deemed, except as so
modified or superseded, to constitute a part of this registration statement.

ITEM 4. DESCRIPTION OF SECURITIES.

         Not Applicable.

ITEM 5. INTERESTS OF NAMED EXPERTS AND COUNSEL.

         Not Applicable.

ITEM 6. INDEMNIFICATION OF DIRECTORS AND OFFICERS.

                                       18

<PAGE>

         Section 145 of the Delaware General Corporation Law ("DGCL") makes
provision for the indemnification of officers and directors in terms
sufficiently broad to indemnify officers and directors under certain
circumstances from liabilities (including reimbursement for expenses incurred)
arising under the Securities Act. Section 145 of the DGCL empowers a corporation
to indemnify its directors and officers and to purchase insurance with respect
to liability arising out of their capacity or status as directors and officers,
provided that this provision shall not eliminate or limit the liability of a
director: (1) for any breach of the director's duty of loyalty to the
corporation or its stockholders, (2) for acts or omissions not in good faith or
which involve intentional misconduct or a knowing violation of law, (3) arising
under Section 174 of the DGCL or (4) for any transaction from which the director
derived an improper personal benefit. The DGCL provides further that the
indemnification permitted thereunder shall not be deemed exclusive of any other
rights to which the directors and officers may be titled under the corporation's
bylaws, any agreement, a vote of stockholders or otherwise.

         Cambrex's Restated Certificate of Incorporation provides for
indemnification of Cambrex's officers and directors to the fullest extent
permitted by the DGCL. Cambrex has purchased directors' and officers' liability
insurance covering liabilities that may be incurred by its directors and
officers in connection with the performance of their duties.

         Cambrex's Bylaws provide a right to indemnification for expenses,
attorney's fees, judgments, fines and amounts paid in settlement actually and
reasonably incurred by any director or officer by reason of the fact that the
director or officer is or was serving or has agreed to serve at the request of
Cambrex as a director or officer of Cambrex or as a director, officer, partner,
fiduciary or trustee of another corporation, partnership, joint venture, trust
or other enterprise, if such officer or director acted in good faith and in a
manner reasonably believed to be in or not opposed to the best interests of the
corporation and, with respect to any criminal action, that the director or
officer had no reasonable cause to believe that his conduct was unlawful. In an
action by or in the right of the corporation, such indemnification shall be
limited to expenses actually and reasonably incurred by such indemnified party
in defense or settlement of such action and no indemnification shall be made in
respect of any matter as to which such indemnified party shall have been
adjudged to be liable to the corporation, unless the Delaware Chancery Court
determines otherwise. Cambrex's Bylaws provide for the advancement of expenses
to an indemnified party upon receipt of an undertaking by the party to repay
those amounts if it is finally determined that the indemnified party is not
entitled to indemnification.

ITEM 7. EXEMPTION FROM REGISTRATION CLAIMED.

         Exemption for the original issuance of the shares of common stock which
may be offered or sold from time to time by the Selling Shareholders pursuant to
the reoffer prospectus contained in this registration statement is claimed under
Section 4(2) of the Securities Act.

ITEM 8.  EXHIBITS.

         The following exhibits are filed with or incorporated by reference into
this registration statement (numbering corresponds to exhibit table in Item 601
of Regulation S-K):

23.1     Consent of PricewaterhouseCoopers LLP

ITEM 9. UNDERTAKINGS.

(1)      The undersigned registrant hereby undertakes:

            (a)   To file, during any period in which offers or sales are being
                  made, a post-effective amendment to this registration
                  statement.

                                       19

<PAGE>

                  (i)   To include any prospectus required by Section 10(a)(3)
                        of the Securities Act;

                  (ii)  To reflect in the prospectus any facts or events arising
                        after the effective date of this registration statement
                        (or the most recent post-effective amendment thereof)
                        which, individually or in the aggregate, represent a
                        fundamental change in the information set forth in this
                        registration statement.

                  (iii) To include any material information with respect to the
                        plan of distribution not previously disclosed in this
                        registration statement or any material change to such
                        information in this registration statement; provided,
                        however, that paragraphs (1)(a)(i) and (1)(a)(ii) do not
                        apply if the information required to be included in a
                        post-effective amendment by those paragraphs is
                        contained in periodic reports filed with or furnished to
                        the Commission by Cambrex pursuant to Section 13 or
                        Section 15(d) of the Exchange Act that are incorporated
                        by reference in this registration statement.

            (b)   That, for the purpose of determining any liability under the
                  Securities Act, each such post-effective amendment shall be
                  deemed to be a new registration statement relating to the
                  securities offered therein, and the offering of such
                  securities at that time shall be deemed to be the initial bona
                  fide offering thereof.

            (c)   To remove from registration by means of a post-effective
                  amendment any of the securities being registered which remain
                  unsold at the termination of the offering.

(2)  The undersigned registrant hereby undertakes that, for purposes of
     determining any liability under the Securities Act, each filing of
     Cambrex's annual report pursuant to Section 13(a) or Section 15(d) of the
     Exchange Act (and, where applicable, each filing of an employee benefit
     plan's annual report pursuant to Section 15(d) of the Exchange Act) that is
     incorporated by reference in this registration statement shall be deemed to
     be a new registration statement relating to the securities offered therein,
     and the offering of such securities at that time shall be deemed to be the
     initial bona fide offering thereof.

(3)  Insofar as indemnification for liabilities arising under the Securities Act
     may be permitted to directors, officers and controlling persons of Cambrex
     pursuant to the foregoing provisions, or otherwise, Cambrex has been
     advised that in the opinion of the Commission such indemnification is
     against public policy as expressed in the Securities Act and is, therefore,
     unenforceable. In the event that a claim for indemnification against such
     liabilities (other than the payment by Cambrex of expenses incurred or paid
     by a director, officer or controlling person of Cambrex in the successful
     defense of any action, suit or proceeding) is asserted by such director,
     officer or controlling person in connection with the securities being
     registered, Cambrex will, unless in the opinion of its counsel the matter
     has been settled by controlling precedent, submit to a court of appropriate
     jurisdiction the question whether such indemnification by it is against
     public policy as expressed in the Securities Act and will be governed by
     the final adjudication of such issue.

                                       20

<PAGE>

                                   SIGNATURES

         Pursuant to the requirements of the Securities Act, Cambrex certifies
that it has reasonable grounds to believe that it meets all of the requirements
for filing on Form S-8 and has duly caused this registration statement to be
signed on its behalf by the undersigned, thereunto duly authorized, in the City
of New York, on this 11th day of August, 2006.

CAMBREX CORPORATION

By:  /s/ Peter E. Thauer
-------------------------------------
Peter E. Thauer

Vice President - Law and Environment,
General Counsel and Secretary

                                       21

<PAGE>

                                POWER OF ATTORNEY

         Each person whose signature appears below hereby severally constitutes
and appoints James A. Mack, Luke M. Beshar and Peter E. Thauer, and each of them
acting singly, as his or her true and lawful attorney-in-fact and agent, with
full and several power of substitution and resubstitution, to sign for him or
her and in his or her name, place and stead in any and all capacities indicated
below, the Registration Statement on Form S-8 filed herewith and any and all
pre-effective and post-effective amendments and supplements to the said
Registration Statement, and to file the same, with exhibits thereto and other
documents in connection therewith, with the Securities and Exchange Commission,
granting unto said attorney-in-fact and agent, full power and authority to do
and perform each and every act and thing requisite and necessary fully to all
intents and purposes as he or she might or could do in person hereby ratifying
and confirming all that said attorney-in-fact and agent, or his or her
substitute, may lawfully do or cause to be done by virtue hereof.

         Pursuant to the requirements of the Securities Act, this registration
statement has been signed below by the following persons in the capacities and
on the dates indicated:

Signature and Title                                     Date

/s/ James A. Mack                                       August 11, 2006
--------------------------------------
James A. Mack
President, Chief Executive Officer
and Chairman of the Board

/s/ Luke M. Beshar                                      August 11, 2006
--------------------------------------
Executive Vice President and
Chief Financial Officer

/s/ David R. Bethune                                    August 11, 2006
--------------------------------------
David R. Bethune
Director

                                       22

<PAGE>

/s/ Rosina B. Dixon                                     August 11, 2006
--------------------------------------
Rosina B. Dixon
Director

/s/ Roy W. Haley                                        August 11, 2006
--------------------------------------
Roy W. Haley
Director

/s/ Kathryn R. Harrigan                                 August 11, 2006
--------------------------------------
Kathryn R. Harrigan, PhD
Director

/s/ Leon J. Hendrix, Jr.                                August 11, 2006
--------------------------------------
Leon J. Hendrix, Jr.
Director

/s/ Ilan Kaufthal                                       August 11, 2006
--------------------------------------
Ilan Kaufthal
Director

/s/ William B. Korb                                     August 11, 2006
--------------------------------------
William B. Korb
Director

/s/ John R. Miller                                      August 11, 2006
--------------------------------------
John R. Miller
Director

/s/ Peter G. Tombros                                    August 11, 2006
--------------------------------------
Peter G. Tombros
Director

                                       23
[{"type": "S-8", "sequence": "1", "filename": "y23918sv8.txt", "description": "FORM S-8", "secsgml_size_bytes": 71169}]
{"company-data": {"conformed-name": "CAMBREX CORP", "cik": "0000820081", "assigned-sic": "2834", "irs-number": "222476135", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-136529", "film-number": "061024623"}, "business-address": {"street1": "ONE MEADOWLANDS PLZ", "city": "E RUTHERFORD", "state": "NJ", "zip": "07073", "phone": "2018043000"}, "mail-address": {"street1": "ONE MEADOWLANDS PLAZA", "city": "E. RUTHERFORD", "state": "NJ", "zip": "07073"}}
As filed with the Securities and Exchange Commission on August 11, 2006.
                                                           Registration No. 333-

                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                    FORM S-8
                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933

                               CAMBREX CORPORATION
               (Exact name of issuer as specified in its charter)

                  Delaware                           22-2476135
          (State of Incorporation)      (I.R.S. Employer Identification No.)

                              One Meadowlands Plaza
                        East Rutherford, New Jersey 07073
                                 (201) 804-3000
          (Address and telephone number of principal executive offices)

             Cambrex Corporation 1996 Performance Stock Option Plan
                            (Full Title of the Plan)

                              Peter E. Thauer, Esq.
                      Vice President - Law and Environment,
                          General Counsel and Secretary
                               Cambrex Corporation
                              One Meadowlands Plaza
                        East Rutherford, New Jersey 07073
                                 (201) 804-3000
            (Name, address and telephone number of agent for service)
CALCULATION OF REGISTRATION FEE
------------------------------------------------------------------------------------------------------------------------
 Title of Securities to      Amount to be     Proposed Maximum Offering       Proposed Maximum           Amount of
     be Registered            Registered         Price Per Share (1)      Aggregate Offering Price    Registration Fee
------------------------------------------------------------------------------------------------------------------------
Common Stock (par      21,500 shares (2)             $20.40                   $438,600.00               $46.93
 value $.10 per share)
------------------------------------------------------------------------------------------------------------------------
Total Registration Fee:                                                                                    $46.93
------------------------------------------------------------------------------------------------------------------------
(1) Estimated solely for the purposes of calculating the amount of the
registration fee pursuant to Rules 457(c) of the Securities Act of 1933, as
amended, on the basis of the average of the high and low prices for shares of
common stock of Cambrex Corporation as reported on the New York Stock Exchange
on August 8, 2006 (within 5 business days before the filing date of this
Registration Statement).

(2) Represents 21,500 shares of common stock previously issued to the selling
shareholders named herein pursuant to the exercise of options granted in
accordance with the terms of the Cambrex Corporation 1996 Performance Stock
Option Plan.
PART I

              INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS

                                EXPLANATORY NOTE

         In accordance with Form S-8 General Instruction C and Rule 429 of the
Securities Act of 1933, as amended (the "Securities Act"), this registration
statement covers the reoffer and resale of 18,500 shares of common stock of
Cambrex Corporation ("Cambrex," the "Company," "we," "us" or "our") previously
issued to certain current and former employees named herein (the "Employees")
pursuant to the exercise of options granted in accordance with the terms of the
Cambrex Corporation 1996 Performance Stock Option Plan. This registration
statement also covers the reoffer and resale of 3,000 shares of common stock of
Cambrex previously issued to certain current and former directors named herein
(the "Directors" and together with the Employees the "Selling Shareholders")
pursuant to the terms of the Cambrex Corporation 1996 Performance Stock Option
Plan.

         This registration statement contains two parts. The first part contains
a "reoffer prospectus" prepared in accordance with Part I of Form S-3 of the
Securities Act. The second part contains information required in this
registration statement pursuant to Part II of Form S-8. This reoffer prospectus
may be used for reoffers or resales on a continuous or delayed basis in the
future of the 21,500 shares of common stock described in the previous paragraph.

                    RESTRICTED SECURITIES REOFFER PROSPECTUS

         The material which follows constitutes a prospectus prepared in
accordance with the applicable requirements of Part I of Form S-3 and General
Instruction C to Form S-8, to be used in connection with reoffers and resales of
restricted securities acquired through an employee benefit plan.
PROSPECTUS

                               CAMBREX CORPORATION

                          21,500 SHARES OF COMMON STOCK

This prospectus relates to 21,500 shares, in the aggregate, of common stock, par
value $.10 per share, of Cambrex Corporation which may be offered or sold from
time to time by the Selling Shareholders. The Selling Shareholders acquired the
shares pursuant to the exercise of options granted in accordance with the terms
of the Cambrex Corporation 1996 Performance Stock Option Plan.

         The price at which a Selling Shareholder may sell any shares of common
stock will be determined by the prevailing market price for such shares or
through a privately negotiated transaction. We will receive no part of the
proceeds of any sale of such shares made hereunder.

         Our common stock is traded on the New York Stock Exchange under the
symbol "CBM". On July 31, 2006 the last reported sale price of our common stock
on the New York Stock Exchange was $21.08 per share.

         The mailing address of our principal executive offices is
PlaceNameplaceOne PlaceNameMeadowlands PlaceTypePlaza, East Rutherford, New
Jersey 07073, and our telephone number is (201) 804-3000.

--------------------------------------------------------------------------------

                  INVESTING IN OUR COMMON STOCK INVOLVES RISKS.
                 PLEASE SEE "RISK FACTORS" BEGINNING ON PAGE 4.

--------------------------------------------------------------------------------

         No person has been authorized to give any information or to make any
representations, other than those contained in this prospectus in connection
with the offering made hereby, and if given or made, such information or
representations must not be relied upon as having been authorized by us, any
Selling Shareholder or any other person. Neither the delivery of this prospectus
nor any sale made hereunder shall, under any circumstances, create any
implication that information herein is correct as of any time subsequent to the
date hereof. This prospectus does not constitute an offer to sell or a
solicitation of an offer to buy any security other than the securities covered
by this prospectus, nor does it constitute an offer to or solicitation of any
person in any jurisdiction in which such offer or solicitation may not lawfully
be made.

--------------------------------------------------------------------------------

         Neither the Securities and Exchange Commission (the "Commission") nor
any state securities commission has approved or disapproved of these securities
or determined if this prospectus is truthful or complete. Any representation to
the contrary is a criminal offense.

                 The date of this prospectus is August 11, 2006.

                                       3
TABLE OF CONTENTS

                                                                            PAGE

CAMBREX CORPORATION..........................................................4
RISK FACTORS.................................................................4
USE OF PROCEEDS..............................................................13
DILUTION.....................................................................13
SELLING SHAREHOLDERS.........................................................14
PLAN OF DISTRIBUTION.........................................................14
EXPERTS......................................................................15
WHERE YOU CAN FIND MORE INFORMATION..........................................15
INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE..............................16

                               CAMBREX CORPORATION

         Cambrex is a leading innovative supplier of human health and
biosciences products to the life sciences industry. Cambrex serves the
innovative and generic pharmaceutical markets and the bioresearch,
biotherapeutic and biopharmaceutical markets, including universities, research
organizations and the government.

                                  RISK FACTORS

         You should carefully consider the following factors and other
information in this prospectus and in our annual reports on Forms 10-K when you
evaluate our business. If any of the following risks occur, the Company's
business, financial condition, operating results and cash flows could be
materially adversely effected. The risks and uncertainties described below are
not the only ones the Company faces. Additionally, risks and uncertainties not
presently known to the Company or that it currently deems immaterial also may
impair its business, financial condition, operating results and cash flows in
the future.

THE COMPANY'S ANALYSIS, CONSIDERATION AND IMPLEMENTATION OF STRATEGIC
ALTERNATIVES MAY MATERIALLY ADVERSELY AFFECT OUR BUSINESS, FINANCIAL CONDITION
OR RESULTS OF OPERATIONS.

         As previously announced, the Company has retained Bear Stearns & Co.,
Inc. to act as advisors to our board of directors in the analysis and
consideration of strategic alternatives to maximize shareholder value, including
the potential sale of certain assets. There are several strategic alternatives
that may be pursued.

         However, we are presently unable to assess what impact any particular
strategic alternative will have on our stock price if accomplished, and our
consideration and implementation of strategic alternatives may not be
successful. Uncertainties and risks relating to our analysis and consideration
of strategic alternatives include but are not limited to:

         -  the analysis and consideration of strategic alternatives may disrupt
            operations and distract members of management and other employees,
            which could adversely affect our results of operations;

         -  the process of exploring strategic alternatives may be more time
            consuming and expensive than currently anticipated;

                                       4
-  we may not be able to successfully achieve the benefits of the
            strategic alternative undertaken; and

         -  perceived uncertainties as to the future direction of the Company
            may result in the loss of employees, customers, clients or business
            partners.

WE MAY PURSUE TRANSACTIONS THAT MAY CAUSE US TO EXPERIENCE SIGNIFICANT CHARGES
TO EARNINGS THAT MAY ADVERSELY AFFECT OUR STOCK PRICE AND FINANCIAL CONDITION.

         We regularly review potential transactions related to technologies,
products, product rights and businesses complementary to our business. These
transactions could include mergers, acquisitions, divestitures, strategic
alliances or licensing agreements. In the future, we may choose to enter into
these transactions at any time. As a result of acquiring businesses or entering
into other significant transactions, we have previously experienced, and may
continue to experience, significant charges to earnings for merger and related
expenses that may include transaction costs, closure costs or costs related to
the write-off of acquired in-process research and development. These costs may
also include substantial fees for investment bankers, attorneys, accountants,
financial printing costs, severance and other closure costs associated with the
elimination of duplicate or discontinued products, employees, operations and
facilities. Although we do not expect these charges to have a material adverse
effect upon our overall financial condition, these charges could have a material
impact on our results of operations for particular quarters or years and they
could possibly have an adverse impact upon the market price of our common stock.

IF WE MAKE ACQUISITIONS, WE MAY EXPERIENCE DIFFICULTY INTEGRATING THE BUSINESSES
WHICH COULD HAVE A MATERIAL ADVERSE EFFECT ON OUR BUSINESS, FINANCIAL CONDITION
AND RESULTS OF OPERATIONS.

         An important part of our business growth strategy is to acquire
products, product lines, technologies and capabilities, including through the
acquisition of businesses and to enhance the Company's position in its niche
markets. We continually explore and conduct discussions with many third parties
regarding possible acquisitions. Our ability to continue to achieve our goals
may depend upon our ability to effectively integrate such businesses, to achieve
cost efficiencies and to manage these businesses as part of our company.
However, we may experience difficulty integrating the merged companies which
could have a material adverse effect on the operating results or financial
condition of the combined company. As a result of uncertainty following an
acquisition and during the integration process, we could experience disruption
in our business or employee base. There is also a risk that key employees of the
combined company may seek employment elsewhere, including with competitors, or
that valued employees may be lost upon the elimination of duplicate functions.
If we are not able to successfully blend our products and technologies with the
acquired business to create the advantages the acquisition was intended to
create, it may effect our results of operations, our ability to develop and
introduce new products and the market price of our common stock. Furthermore,
there may be overlap between our products, services or customers, and the
combined company may create conflicts in relationships or other commitments
detrimental to the integrated businesses.

IF WE FAIL TO IMPROVE THE OPERATIONS OF FUTURE ACQUIRED BUSINESSES, WE MAY BE
UNABLE TO ACHIEVE OUR GROWTH STRATEGY.

         Some of the businesses we have acquired or will acquire had or may have
significantly lower operating margins than we do and/or operating losses prior
to the time we acquired them. In the past, we have occasionally experienced
temporary delays in improving the operating margins of these acquired

                                       5
businesses. In the future, if we are unable to improve the operating margins of
acquired businesses or operate them profitably, we may be unable to achieve our
growth strategy.

PHARMACEUTICAL, BIOPHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES MAY DISCONTINUE OR
DECREASE THEIR USAGE OF OUR SERVICES.

         We depend on pharmaceutical, biopharmaceutical and biotechnology
companies that use our services for a large portion of our revenues. Although
there has been a trend among these companies to outsource therapeutic production
functions, this trend may not continue. We have observed increasing pressure on
the part of our customers to reduce spending, including the use of our services,
as a result of negative economic trends generally and in the pharmaceutical
industry. If these companies discontinue or decrease their usage of our
services, including as a result of an economic slowdown in the overall
country-regionplaceUnited States or foreign economies, our revenues and earnings
could be lower than we expect and our revenues may decrease or not grow at
historical rates.

COMPETITION IN THE LIFE SCIENCES RESEARCH MARKET, AND/OR A REDUCTION IN DEMAND
FOR OUR PRODUCTS, COULD REDUCE SALES.

         The markets for our products are competitive and price sensitive. Other
life science suppliers have significant financial, operational, sales and
marketing resources, and experience in research and development. These and other
companies may have developed or could in the future develop new technologies
that would compete with our products or render our products obsolete. If a
competitor develops superior technology or cost-effective alternatives to our
products or services, our business, operating results, and financial condition
could be seriously harmed. In addition, demand for our products may weaken due
to reduction in research and development budgets, loss of distributors or other
factors, which would have an adverse effect on our financial condition.

         The markets for certain of our products are also subject to specific
competitive risks and can be highly price competitive. Our competitors have
competed in the past by lowering prices on certain products. Our competitors may
lower prices on these or other products in the future and we may, in certain
cases, respond by lowering our prices. This would reduce revenues and profits.
Conversely, failure to anticipate and respond to price competition may hurt our
market share.

         We believe that customers in our markets display loyalty to their
initial supplier of a particular product. Therefore, it may be difficult to
generate sales to potential customers who have purchased products from
competitors. To the extent we are unable to be the first to develop and supply
new products, our competitive position may suffer.

OUR FAILURE TO OBTAIN NEW CONTRACTS OR RENEWED CONTRACTS OR CANCELLATION OF
EXISTING CONTRACTS MAY ADVERSELY EFFECT OUR BUSINESS, FINANCIAL CONDITION AND
RESULTS OF OPERATIONS AND MAKE OUR REVENUE DIFFICULT TO PREDICT.

         Many of our contracts are short-term in duration. As a result, we must
continually replace our contracts with new contracts to sustain our revenue. In
addition, many of our long-term contracts may be cancelled or delayed by clients
for any reason upon notice. Contracts may be terminated for a variety of
reasons, including termination of product development, failure of products to
satisfy safety requirements, unexpected or undesired results from use of the
product or the client's decision to forego a particular study. The Company
currently has a long-term sales contract within the Human Health segment that
accounts for more than 10% of segment sales that is scheduled to expire at the
end of 2008. There is no guarantee that this contract will be renewed. Our
failure to obtain new contracts or renew contracts or the

                                       6
cancellation or delay of existing contracts could have a material adverse effect
on our business, financial condition and results of operations.

         Furthermore, because our revenue is primarily generated on a
contract-by-contract or purchase order basis, our revenue is difficult to
predict and contributes to the variability of our financial results from period
to period. In addition, we do not believe that a backlog of contracts is a
meaningful indicator of our future revenue because much of our revenue is
resulting from short-term contracts or purchase orders and these contracts can
often be terminated for many reasons.

THE BIOPHARMA BUSINESS SEGMENT HAS EXPERIENCED AND MAY CONTINUE TO EXPERIENCE
SIGNIFICANT VOLATILITY IN PROFITABILITY AND THERE ARE NO ASSURANCES THAT IT WILL
RETURN TO ITS HISTORIC PROFITABILITY LEVEL.

         The Company's Biopharma segment provides process development and
manufacturing services on a contract basis to biopharmaceutical companies. This
business has a very high fixed cost structure and its customers are often
dependent on the availability of funding and pursuing drugs that are in earlier
stages of clinical trials, and thus have high failure rates. Losses of one or
more customers can result in significant swings in profitability from quarter to
quarter and year to year. Returning to historic profitability levels is
dependent on the Company generating significant additional revenues from
existing and new customers, which can not be assured.

THE COMPANY COULD BE SUBJECT TO ADDITIONAL IMPAIRMENT CHARGES IN THE FUTURE.

         During 2004 and 2005, the Company recorded impairment charges to reduce
goodwill and long-lived assets in 2005. The Company may be subject to additional
impairment charges if the business units do not perform at or near projected
levels in the future. Should the profit forecast for these businesses be revised
significantly downward, the Company may incur additional impairment charges.

OUR OPERATING RESULTS MAY UNEXPECTEDLY FLUCTUATE IN FUTURE PERIODS.

         The Company's revenue and operating results have fluctuated, and could
continue to fluctuate, on a quarterly basis. The operating results for a
particular quarter may be lower than expected as a result of a number of
factors, including the timing of contracts; the delay or cancellation of a
contract; the mix of services provided; seasonal slowdowns in different parts of
the world; the timing of start-up expenses for new services and facilities; and
changes in government regulations. Because a high percentage of the Company's
costs are relatively fixed in the short term (such as the cost of maintaining
facilities and compensating employees), any one of these factors could have a
significant impact on the Company's quarterly results. In some quarters, the
Company's revenue and operating results may fall below the expectations of
securities analysts and investors due to any of the factors described above. In
such event, the trading price of the Company's common stock would likely
decline, even if the decline in revenue did not have any long-term adverse
implications for the Company's business.

OUR MARKET SHARE DEPENDS ON NEW PRODUCT INTRODUCTIONS AND ACCEPTANCE.

         Rapid technological change and frequent new product introductions are
typical of the market for certain of our products and services. Our future
success will depend in part on continuous, timely development and introduction
of new products that address evolving market requirements and are attractive to
customers. We believe successful new product introductions provide a significant
competitive advantage because customers make an investment of time in selecting
and learning to use a new product, and are reluctant to switch thereafter. We
spend significant resources on internal research and development, as well as on
technology development elsewhere to support our effort to develop and

                                       7
introduce new products. To the extent that we fail to introduce new and
innovative products, we could fail to obtain an adequate return on these
investments and could lose market share to our competitors, which may be
difficult to regain. An inability, for technological or other reasons, to
develop successfully and introduce new products could reduce our growth rate or
otherwise damage our business.

         In the past, we have experienced, and may experience in the future,
delays in the development and introduction of products. We cannot be assured
that we will keep pace with the rapid change in life sciences research, or that
our new products will adequately meet the requirements of the marketplace or
achieve market acceptance. Some of the factors effecting market acceptance of
our products include:

         -  availability, quality and price as compared to competitive products;

         -  the functionality of new and existing products;

         -  the timing of introduction of our products as compared to
            competitive products;

         -  scientists' and customers' opinions of the product's utility and our
            ability to incorporate their feedback into future products;

         -  general trends in life sciences research.

         The expenses or losses associated with unsuccessful product development
activities or lack of market acceptance of our new products could adversely
affect our business, financial condition and results of operations.

FAILURE TO OBTAIN PRODUCTS AND COMPONENTS FROM THIRD-PARTY MANUFACTURERS COULD
AFFECT OUR ABILITY TO MANUFACTURE AND DELIVER OUR PRODUCTS.

         We rely on third-party manufacturers to supply many of our raw
materials, product components, and in some cases, entire products. In addition,
we have a single source for supplies of some raw materials and components to our
products. Manufacturing problems may occur with these and other outside sources.
If such problems occur, we cannot ensure that we will be able to manufacture our
products profitably or on time.

ANY SIGNIFICANT REDUCTION IN GOVERNMENT REGULATION OF THE DRUG DEVELOPMENT
PROCESS COULD HAVE A MATERIAL ADVERSE EFFECT ON OUR BUSINESS, FINANCIAL
CONDITION AND RESULTS OF OPERATIONS.

         The design, development, testing, manufacturing and marketing of
biotechnology and pharmaceutical products are subject to extensive regulation by
governmental authorities, including the U.S. Food and Drug Administration
("FDA") and comparable regulatory authorities in other countries. The Company's
business depends in part on strict government regulation of the drug development
process. Legislation may be introduced and enacted from time to time to modify
regulations administered by the FDA and governing the drug approval process. Any
significant reduction in the scope of regulatory requirements or the
introduction of simplified drug approval procedures could have a material
adverse effect on the Company's business, financial condition and results of
operations.

VIOLATIONS OF CGMP AND OTHER GOVERNMENT REGULATIONS COULD HAVE A MATERIAL
ADVERSE EFFECT ON OUR BUSINESS, FINANCIAL CONDITION AND RESULTS OF OPERATIONS.

                                       8
All facilities and manufacturing techniques used for manufacturing of
products for clinical use or for commercial sale in the
country-regionplaceUnited States must be operated in conformity with current
Good Manufacturing Practices ("cGMP") regulations as required by the FDA. The
Company's facilities are subject to scheduled periodic regulatory and customer
inspections to ensure compliance with cGMP and other requirements applicable to
such products. A finding that the Company had materially violated these
requirements could result in regulatory sanctions, the loss of a customer
contract, the disqualification of data for client submissions to regulatory
authorities and/or a mandated closing of the Company's facilities. Any such
material violations would have a material adverse effect on the Company's
business, financial condition and results of operations.

         The Commission is currently conducting an investigation into the
Company's inter-company accounting procedures from the period 1997-2001. The
investigation began during the first half of 2003 after the Company voluntarily
disclosed certain matters related to inter-company accounts for the five-year
period ending December 31, 2001 that resulted in the restatement of the
Company's financial statements for those years. The Company is fully cooperating
with the SEC and does not expect further revisions to its historical financial
statements relating to these issues. This investigation could lead to an adverse
outcome and adversely effect our business, financial condition, results of
operations and cash flows.

LITIGATION MAY HARM OUR BUSINESS OR OTHERWISE NEGATIVELY IMPACT OUR MANAGEMENT
AND FINANCIAL RESOURCES.

         Substantial, complex or extended litigation could cause the Company to
incur large expenditures and distract our management. For example, lawsuits by
employees, stockholders, counterparties to acquisition and divestiture
contracts, collaborators, distributors, customers, or end-users of our products
or services could be very costly and substantially disrupt our business.
Disputes from time to time with such companies or individuals are not uncommon,
and we cannot assure you that we will always be able to resolve such disputes
out of court or on terms favorable to the Company.

         The Company is involved in a number of lawsuits including a class
action lawsuit filed against Cambrex and certain current Company officers
alleging the failure to disclose in a timely fashion the restatement of results
for the five-year period ending December 31, 2001 as discussed in the risk
factor above, as well as the loss of a significant contract at our Baltimore
facility. If this matter, or any of the Company's other lawsuits, is resolved in
an unfavorable manner, they could have a material adverse effect on the
operating results and cash flows in future periods.

LOSS OF KEY PERSONNEL COULD HURT OUR BUSINESS.

         The Company depends on a number of key executives. The loss of services
of any of the Company's key executives could have a material adverse effect on
the Company's business.

         The Company also depends on its ability to attract and retain qualified
scientific and technical employees. There can be no assurance the Company will
be able to retain its existing scientific and technical employees, or to attract
and retain additional qualified employees. The Company's inability to attract
and retain qualified scientific and technical employees would have a material
adverse effect on the Company's business, financial condition and results of
operations.

POTENTIAL PRODUCT LIABILITY CLAIMS, ERRORS AND OMISSIONS CLAIMS IN CONNECTION
WITH SERVICES WE PERFORM AND POTENTIAL LIABILITY UNDER INDEMNIFICATION
AGREEMENTS BETWEEN US AND OUR OFFICERS AND DIRECTORS COULD ADVERSELY EFFECT OUR
EARNINGS AND FINANCIAL CONDITION.

                                       9
The Company manufactures products intended for use by the public. In
addition, the Company's services include the manufacture of pharmaceutical and
biologic products to be tested in human clinical trials and for consumption by
humans. These activities could expose the Company to risk of liability for
personal injury or death to persons using such products, although the Company
does not presently market or sell the products to end users. The Company seeks
to reduce its potential liability through measures such as contractual
indemnification provisions with clients (the scope of which may vary from
client-to-client, and the performances of which are not secured), exclusion of
services requiring diagnostic or other medical services, and insurance
maintained by clients. The Company could be materially and adversely effected if
it were required to pay damages or incur defense costs in connection with a
claim that is outside the scope of the indemnification agreements, if the
indemnity, although applicable, is not performed in accordance with its terms or
if the Company's liability exceeds the amount of applicable insurance or
indemnity. In addition, the Company could be held liable for errors and
omissions in connection with the services it performs. The Company currently
maintains product liability and errors and omissions insurance with respect to
these risks. There can be no assurance, however, that the Company's insurance
coverage will be adequate or that insurance coverage will continue to be
available on terms acceptable to the Company.

         The Company also indemnifies its officers and directors for certain
events or occurrences while the officer or director is, or was serving, at the
Company's request in such capacity. The maximum potential amount of future
payments the Company could be required to make under these indemnification
agreements is unlimited; however, the Company has a "Director and Officer"
insurance policy that covers a portion of any potential exposure. The Company
could be materially and adversely effected if it were required to pay damages or
incur legal costs in connection with a claim above its insurance limits.

ASSESSMENTS BY VARIOUS TAX AUTHORITIES MAY BE MATERIALLY DIFFERENT THAN WE HAVE
PROVIDED FOR AND WE MAY EXPERIENCE SIGNIFICANT VOLATILITY IN OUR ANNUAL AND
QUARTERLY EFFECTIVE TAX RATE.

         As a matter of course, the Company is regularly audited by federal,
state, and foreign tax authorities. From time to time, these audits result in
proposed assessments. While the Company believes that it has adequately provided
for any such assessments, future settlements may be materially different than we
have provided for and negatively effect our earnings.

         Since 2003, the geographic mix of income has resulted in the
recording of a valuation allowance against all net domestic deferred tax assets.
Going forward, until such time as the Company's domestic profitability is
restored and considered by management to be sustainable for the foreseeable
future, the Company will not record the income tax benefit or expense for
domestic pre-tax losses and income respectively, and as such may experience
significant volatility in its effective tax rate.

WE HAVE A SIGNIFICANT AMOUNT OF DEBT THAT COULD ADVERSELY EFFECT OUR FINANCIAL
CONDITION.

         The Company has a $277,500 revolving credit facility of which $81,943
was outstanding at December 31, 2005. In addition, the Company had privately
placed notes of $100,000 (repaid in January 2006 by drawing down our existing
revolving credit facility).

         Even if we are able to meet our debt service obligations, the amount of
debt we have could adversely effect us in a number of ways, including:

                                       10
-  limiting our ability to obtain any necessary financing in the future
            for working capital, capital expenditures, debt service
            requirements, or other purposes;

         -  limiting our flexibility in planning for, or reacting to, changes in
            our business;

         -  placing us at a competitive disadvantage relative to our competitors
            who have lower levels of debt;

         -  making us more vulnerable to a downturn in our business or the
            economy generally;

         -  requiring us to use a substantial portion of our cash to pay
            principal and interest on our debt, instead of contributing those
            funds to other purposes such as working capital and capital
            expenditures.

INTERNATIONAL UNREST OR FOREIGN CURRENCY FLUCTUATIONS COULD ADVERSELY EFFECT OUR
RESULTS.

         Our international revenues, which include revenues from our non-U.S.
subsidiaries and export sales from the country-regionplaceU.S., represented 62%
of our product revenues in 2005 and 61% of our product revenues in 2004. We
expect that international revenues will continue to account for a significant
percentage of our revenues for the foreseeable future.

         There are a number of risks arising from our international business,
including:

         -  foreign currencies we receive for sales outside the
            country-regionplaceU.S. could be subject to unfavorable exchange
            rates with the U.S. dollar and reduce the amount of revenue that we
            recognize;

         -  the possibility that unfriendly nations or groups could boycott our
            products;

         -  general economic and political conditions in the markets in which we
            operate;

         -  potential increased costs associated with overlapping tax
            structures;

         -  more limited protection for intellectual property rights in some
            countries;

         -  unexpected changes in regulatory requirements;

         -  the difficulties of compliance with a wide variety of foreign laws
            and regulations;

         -  longer accounts receivable cycles in certain foreign countries; and

         -  import and export licensing requirements.

         A significant portion of our business is conducted in currencies other
than the U.S. dollar, which is our reporting currency. We recognize foreign
currency gains or losses arising from our operations in the period incurred. As
a result, currency fluctuations between the U.S. dollar and the currencies in
which we do business have caused and will continue to cause foreign currency
transaction gains and losses. We cannot predict the effects of exchange rate
fluctuations upon our future operating results because of the number of
currencies involved, the variability of currency exposures, and the potential
volatility of currency exchange rates. We engage in limited foreign exchange
hedging transactions to manage our foreign currency exposure, but our strategies
are short-term in nature and may not adequately protect our operating results
from the full effects of exchange rate fluctuations.

                                       11
THE MARKET PRICE OF OUR STOCK COULD BE VOLATILE.

         The market price of our common stock has been subject to volatility
and, in the future, the market price of our common stock may fluctuate
substantially due to a variety of factors, including:

         -  quarterly fluctuations in our operating income and earnings per
            share results;

         -  technological innovations or new product introductions by us or our
            competitors;

         -  economic conditions;

         -  disputes concerning patents or proprietary rights;

         -  changes in earnings estimates and market growth rate projections by
            market research analysts;

         -  sales of common stock by existing holders;

         -  loss of key personnel; and

         -  securities class actions or other litigation.

         The market price for our common stock may also be effected by our
ability to meet analysts' expectations. Any failure to meet such expectations,
even slightly, could have an adverse effect on the market price of our common
stock. In addition, the stock market is subject to extreme price and volume
fluctuations. This volatility has had a significant effect on the market prices
of securities issued by many companies for reasons unrelated to the operating
performance of these companies.

INCIDENTS RELATED TO HAZARDOUS MATERIALS COULD ADVERSELY EFFECT OUR BUSINESS.

         Portions of our operations require the controlled use of hazardous
materials. Although we are diligent in designing and implementing safety
procedures to comply with the standards prescribed by federal, state, and local
regulations, the risk of accidental contamination of property or injury to
individuals from these materials cannot be completely eliminated. In the event
of such an incident, we could be liable for any damages that result, which could
adversely effect our business.

         Additionally, any incident could partially or completely shut down our
research and manufacturing facilities and operations.

         We generate waste that must be transported to approved storage,
treatment and disposal facilities. The transportation and disposal of such waste
are required to meet applicable state and federal statutes and regulations. The
storage, treatment and disposal of such waste potentially exposes us to
environmental liability if, in the future, such transportation and disposal are
deemed to have violated such statues and/or regulations or if the storage,
treatment and disposal facilities are inadequate and are proved to have damaged
the environment.

         The Company is also party to several environmental remediation
investigations and cleanups and, along with other companies, has been named a
"potential responsible party" for certain waste disposal sites. The Company has
also retained the liabilities with respect to certain pre-closing environmental
matters associated with the sale of the Rutherford Chemicals business. After
reviewing information

                                       12
currently available, management believes any amount paid in excess of accrued
liabilities will not have a material effect on its business, financial condition
or results of operations. However, these matters, if resolved in a manner
different from the estimates, could have a material adverse effect on the
financial condition, operating results and cash flows when resolved in future
reporting periods.

THE POSSIBILITY WE WILL BE UNABLE TO PROTECT OUR TECHNOLOGIES COULD EFFECT OUR
ABILITY TO COMPETE.

         Our success depends to a significant degree upon our ability to develop
proprietary products and technologies. However, we cannot be assured that
patents will be granted on any of our patent applications. We also cannot be
assured that the scope of any of our issued patents will be sufficiently broad
to offer meaningful protection. We only have patents issued in selected
countries. Therefore, third parties can make, use, and sell products covered by
our patents in any country in which we do not have patent protection. In
addition, our issued patents or patents we license could be successfully
challenged, invalidated or circumvented so that our patent rights would not
create an effective competitive barrier. We provide our customers the right to
use our products under label licenses that are for research purposes only. These
licenses could be contested, and we cannot be assured that we would either be
aware of an unauthorized use or be able to enforce the restrictions in a
cost-effective manner.

         If a third party claimed an intellectual property right to technology
we use, we may need to discontinue an important product or product line, alter
our products and processes, defend our right to use such technology in court or
pay license fees. Although we may, under these circumstances, attempt to obtain
a license to such intellectual property, we may not be able to do so on
favorable terms, or at all. Additionally, if our products are found to infringe
on a third party's intellectual property, we may be required to pay damages for
past infringement, and lose the ability to sell certain products or receive
licensing revenues.

COMPLIANCE WITH CHANGING REGULATION OF CORPORATE GOVERNANCE AND PUBLIC
DISCLOSURE MAY RESULT IN ADDITIONAL EXPENSE.

         Changing laws, regulations and standards relating to corporate
governance and public disclosure, including the Sarbanes-Oxley Act of 2002, are
creating uncertainty for companies. These new or changed laws and standards are
subject to multiple interpretations, in many cases due to their lack of
specification. As a result, their application in practice may evolve over time
as new guidance is provided by regulatory and governing bodies which could
result in higher costs necessitated by revisions to disclosures and governance
practices. We are committed to maintaining high standards of corporate
governance and public disclosure. As a result of the efforts to comply with the
evolving laws and regulations increased general and administrative expenses have
been experienced and are likely to continue. In particular, our efforts to
comply with Section 404 of the Sarbanes-Oxley Act of 2002, and the related
assessments have required commitment of significant internal and external
financial and operational resources.

                                 USE OF PROCEEDS

         We will not receive any of the proceeds from the sale of any shares of
our common stock by the Selling Shareholders pursuant to this reoffer
prospectus. All such proceeds, net of brokerage commissions, if any, will be
received by the Selling Shareholders.

                                    DILUTION

         Because any Selling Shareholders who offer and sell their shares of
common stock covered by this prospectus may do so at various times, at prices
and at terms then prevailing or at prices related to the then current market
price, or in negotiated transactions, we have not included in this prospectus

                                       13
information about the dilution (if any) to the public arising from these sales.

                              SELLING SHAREHOLDERS

         The shares of common stock to which this prospectus relates may be
offered or sold from time to time by the Selling Shareholders.

         The following table sets forth certain information as to the beneficial
ownership of Cambrex's common stock as of August 4, 2006 for each Selling
Shareholder (a current or former employee or director of the Company, as
indicated below).
--------------------------------------------------------------------------------------------------------------------
                                                                                                PERCENTAGE OF SHARES
                             NUMBER OF SHARES      MAXIMUM NUMBER OF       NUMBER OF SHARES      BENEFICIALLY OWNED
     NAME OF SELLING        BENEFICIALLY OWNED   SHARES ELIGIBLE TO BE    BENEFICIALLY OWNED     AFTER THE OFFERING
     SHAREHOLDER (1)         PRIOR TO OFFERING         OFFERED (2)         AFTER THE OFFERING             (7)
--------------------------------------------------------------------------------------------------------------------
Stephen Colasuonno (4)             500                   500                         0                    *
Dave Goodman (4)                 3,833                 3,000                       833                    *
George Goodman (5)               7,816                 1,500                     6,316                    *
Leon Hendrix Jr. (6)            19,302                 1,500                    17,802                    *
Theresa Hernan (4)               5,004                 4,500                       504                    *
Carl Johansson (4)               4,500                 4,500                         0                    *
Michael Lafond (3)               5,689                 4,500                     1,189                    *
Ulf Sjoestrand (4)               1,000                 1,000                         0                    *
Roop Kumar (3)                     500                   500                         0                    *
--------------------------------------------------------------------------------------------------------------------
* Less than 1%.

(1)   Each Selling Shareholder received shares of common stock pursuant to the
      exercise on April 25, 2006 of options granted in accordance with the terms
      of the Cambrex Corporation 1996 Performance Stock Option Plan, except for
      Roop Kumar who exercised on April 24, 2006.

(2)   Only the shares acquired in connection with the Cambrex Corporation 1996
      Performance Stock Option Plan described in note (1) are eligible to be
      offered under this prospectus.

(3)   Former employee.

(4)   Current employee.

(5)   Former director.

(6)   Current director.

(7)   For the purpose of this table, the percent of issued and outstanding
      shares of common stock held by each Selling Shareholder has been
      calculated on the basis of 26,753,156 shares of common stock issued and
      outstanding (excluding treasury shares) on August 8, 2006.

                              PLAN OF DISTRIBUTION

         We are registering the shares of common stock covered by this
prospectus for the Selling Shareholders or their pledgees, donees, transferees
or other successors-in-interest as a gift, partnership distribution or other
non-sale-related-transfer after the date of this prospectus, who may sell the
shares from time to time. The Selling Shareholders will act independently of us
in making decisions with respect to the timing, manner and size of each sale.
The sales may be made on one or more exchanges or otherwise, at prices and at
terms then prevailing or at prices related to the then current market price, or
in negotiated transactions. The Selling Shareholders may effect such
transactions by selling the shares to or through broker-dealers or directly to
purchasers (in the event of a private sale). The shares may be sold by one or
more of, or a combination of, the following:

                                       14
-  a block trade in which the broker-dealer so engaged will attempt to
            sell the shares as agent but may position and resell a portion of
            the block as principal to facilitate the transaction;

         -  purchases by a broker-dealer as principal and resale by such
            broker-dealer for its account pursuant to this prospectus;

         -  ordinary brokerage transactions and transactions in which the broker
            solicits purchasers; and

         -  in privately negotiated transactions.

         Certain Selling Shareholders may enter into hedging transactions with
broker-dealers in connection with distributions of the shares or otherwise. In
such transactions, broker-dealers may engage in short sales of the shares in the
course of hedging the positions they assume with certain Selling Shareholders.
Certain Selling Shareholders may also sell the shares short and redeliver the
shares to close out such short positions. Such Selling Shareholders may enter
into option or other transactions with broker-dealers which require the delivery
to the broker-dealer of the shares. The broker-dealer may then resell or
otherwise transfer such shares pursuant to this prospectus.

         Certain Selling Shareholders also may loan or pledge the shares to a
broker-dealer. The broker-dealer may sell the shares so loaned, or upon a
default the broker-dealer may sell the pledged shares, pursuant to this
prospectus.

         Broker-dealers or agents may receive compensation in the form of
commissions, discounts or concessions from Selling Shareholders. Broker-dealers
or agents may also receive compensation from the purchasers of the shares for
whom they act as agents or to whom they sell as principals, or both. In such
cases, usual and customary brokerage fees will be paid by the Selling
Shareholders. Broker-dealers or agents and any other participating
broker-dealers or the Selling Shareholders may be deemed to be "underwriters"
within the meaning of Section 2(11) of the Securities Act in connection with
sales of the shares. Accordingly, any such commission, discount or concession
received by them and any profit on the resale of the shares purchased by them
may be deemed to be underwriting discounts or commissions under the Securities
Act. Because Selling Shareholders may be deemed to be "underwriters" within the
meaning of Section 2(11) of the Securities Act, the Selling Shareholders will be
subject to the prospectus delivery requirements of the Securities Act. In
addition, any securities covered by this prospectus which qualify for sale
pursuant to Rule 144 promulgated under the Securities Act may be sold under Rule
144 rather than pursuant to this prospectus. There is no underwriter or
coordinating broker acting in connection with the proposed sale of the shares by
the Selling Shareholders.

         We will bear all costs, expenses and fees in connection with the
registration of the shares. The Selling Shareholders will bear all commissions
and discounts, if any, attributable to the sales of the shares. The Selling
Shareholders may agree to indemnify any broker-dealer or agent that participates
in transactions involving sales of the shares against certain liabilities,
including liabilities arising under the Securities Act.

                                       15
EXPERTS

         The financial statements and management's assessment of the
effectiveness of internal control over financial reporting (which is included in
Management's Report on the Internal Control over Financial Reporting)
incorporated in this Prospectus by reference to the Annual Report on Form 10-K
for the year ended December 31, 2005 have been so incorporated in reliance on
the report (which contains an adverse opinion on the effectiveness of internal
control over financial reporting) of PricewaterhouseCoopers LLP, an independent
registered public accounting firm, given on the authority of said firm as
experts in auditing and accounting.

                       WHERE YOU CAN FIND MORE INFORMATION

         We file annual, quarterly and special reports, proxy statements and
other information with the Securities and Exchange Commission. You may read and
copy any of the information on file with the Commission at the Commission's
Public Reference Room at address Street 450 Fifth Street, N.W., Room 1024,
Washington, State D.C. Postal Code 20549. Please call the Commission at
1-800-SEC-0330 for further information on the Public Reference Room. In
addition, the Commission maintains an Internet site at http://www.sec.gov that
contains reports, proxy and information statements, and other information
regarding issuers that file electronically with the Commission. We began filing
documents with the Commission electronically on March 22, 1994. Our filings with
the Commission are also available to the public from commercial document
retrieval services. Some of our filings are available at http://www.cambrex.com.

         Our common stock is listed on the New York Stock Exchange. Reports and
other information concerning Cambrex may be inspected at the offices of the New
York Stock Exchange, address Street 20 Broad Street, City New York, State New
York Postal Code 10005.

         We filed a registration statement on Form S-8 to register with the
Commission the shares of common stock offered by this prospectus. This document
is part of that registration statement and constitutes a prospectus of Cambrex.
As permitted by Commission rules, this document does not contain all the
information you can find in the registration statement or exhibits to the
registration statement.

                 INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

         The Commission allows us to incorporate by reference information into
this document, which means that we can disclose important information to you by
referring you to another document filed separately with the Commission. The
information incorporated by reference is deemed to be part of this document,
except for any information superseded by information in this document or a
document subsequently filed by us. This document incorporates by reference the
documents set forth below that we have previously filed with the Commission.
These documents contain important information about us and our financial
performance.

(a)  Annual Report on Form 10-K         Year ended December 31, 2005

(b)  Quarterly Reports on Form 10-Q     Quarter Ended March 31, 2006 and
                                        June 30, 2006

(c)  Current Reports on Form 8-K (to    Dated January 4, 2006, February 3, 2006,
     the extent not furnished)          February 7, 2006, March 20, 2006,
                                        May 3, 2006, and August 4, 2006

(d)  The description of the shares of common stock of Cambrex contained in the
     registration statement filed pursuant to Section 12 of the Securities
     Exchange Act of 1934, as amended ("Exchange Act"),

                                       16
including any amendment or report filed for the purpose of updating such
      description.

(e)  All documents subsequently filed by us pursuant to Section 13(a), 13(c), 14
     or 15(d) of the Exchange Act, prior to the termination of the offering,
     shall be deemed to be incorporated by reference into this prospectus.

         Copies of these filings, excluding all exhibits unless an exhibit has
been specifically incorporated by reference in this document, are available from
us, at no cost, by writing or telephoning us at:

         Cambrex Corporation
         One PlaceNameplaceMeadowlands PlaceTypePlaza
         East Rutherford, StateNew Jersey PostalCode07073
         Tel: (201) 804-3000
         Attn: Secretary

         You should rely only on the information incorporated by reference or
provided in this prospectus or any prospectus supplement. We have authorized no
one to provide you with different information. You should not assume that the
information in this prospectus or any prospectus supplement is accurate as of
any date other than the date on the front of that document, regardless of the
time of delivery of this prospectus or of any sale of shares of common stock.

                                       17
PART II
                           INFORMATION REQUIRED IN THE
                             REGISTRATION STATEMENT

ITEM 3. INCORPORATION OF DOCUMENTS BY REFERENCE.

         The following documents or extracts of documents, which previously have
been filed by Cambrex with the Commission, are incorporated herein by reference
and made a part hereof:

(a)  Annual Report on Form 10-K         Year ended December 31, 2005

(b)  Quarterly Reports on Form 10-Q     Quarter Ended March 31, 2006 and
                                        June 30, 2006

(c)  Current Reports on Form 8-K (to    Dated January 4, 2006, February 3, 2006,
     the extent not furnished)          February 7, 2006, March 20, 2006,
                                        May 3, 2006 and August 4, 2006

(d)  The description of the shares of common stock of Cambrex contained in the
     registration statement filed pursuant to Section 12 of the Exchange Act,
     including any amendment or report filed for the purpose of updating such
     description.

(e)  All other reports filed by us pursuant to Section 13(a) or 15(d) of the
     Exchange Act since the end of the fiscal year covered by the Annual Report
     referred to in (a) above.

(f)  All documents filed by us pursuant to Sections 13(a), 13(c), 14 or 15(d) of
     the Exchange Act, after the date hereof and prior to the filing of a
     post-effective amendment which indicates that all securities covered hereby
     have been sold or which deregisters all securities covered hereby then
     remaining unsold, such documents to form a part hereof, commencing on the
     respective dates on which the documents are filed.

         For purposes of this registration statement, any document or any
statement deemed to be incorporated by reference herein or contained in an
incorporated document shall be deemed to be modified or superseded for purposes
hereof to the extent that a statement contained herein or in any other
subsequently filed incorporated document modifies or supersedes such statement.
Any such statement so modified or superseded shall not be deemed, except as so
modified or superseded, to constitute a part of this registration statement.

ITEM 4. DESCRIPTION OF SECURITIES.

         Not Applicable.

ITEM 5. INTERESTS OF NAMED EXPERTS AND COUNSEL.

         Not Applicable.

ITEM 6. INDEMNIFICATION OF DIRECTORS AND OFFICERS.

                                       18
Section 145 of the Delaware General Corporation Law ("DGCL") makes
provision for the indemnification of officers and directors in terms
sufficiently broad to indemnify officers and directors under certain
circumstances from liabilities (including reimbursement for expenses incurred)
arising under the Securities Act. Section 145 of the DGCL empowers a corporation
to indemnify its directors and officers and to purchase insurance with respect
to liability arising out of their capacity or status as directors and officers,
provided that this provision shall not eliminate or limit the liability of a
director: (1) for any breach of the director's duty of loyalty to the
corporation or its stockholders, (2) for acts or omissions not in good faith or
which involve intentional misconduct or a knowing violation of law, (3) arising
under Section 174 of the DGCL or (4) for any transaction from which the director
derived an improper personal benefit. The DGCL provides further that the
indemnification permitted thereunder shall not be deemed exclusive of any other
rights to which the directors and officers may be titled under the corporation's
bylaws, any agreement, a vote of stockholders or otherwise.

         Cambrex's Restated Certificate of Incorporation provides for
indemnification of Cambrex's officers and directors to the fullest extent
permitted by the DGCL. Cambrex has purchased directors' and officers' liability
insurance covering liabilities that may be incurred by its directors and
officers in connection with the performance of their duties.

         Cambrex's Bylaws provide a right to indemnification for expenses,
attorney's fees, judgments, fines and amounts paid in settlement actually and
reasonably incurred by any director or officer by reason of the fact that the
director or officer is or was serving or has agreed to serve at the request of
Cambrex as a director or officer of Cambrex or as a director, officer, partner,
fiduciary or trustee of another corporation, partnership, joint venture, trust
or other enterprise, if such officer or director acted in good faith and in a
manner reasonably believed to be in or not opposed to the best interests of the
corporation and, with respect to any criminal action, that the director or
officer had no reasonable cause to believe that his conduct was unlawful. In an
action by or in the right of the corporation, such indemnification shall be
limited to expenses actually and reasonably incurred by such indemnified party
in defense or settlement of such action and no indemnification shall be made in
respect of any matter as to which such indemnified party shall have been
adjudged to be liable to the corporation, unless the Delaware Chancery Court
determines otherwise. Cambrex's Bylaws provide for the advancement of expenses
to an indemnified party upon receipt of an undertaking by the party to repay
those amounts if it is finally determined that the indemnified party is not
entitled to indemnification.

ITEM 7. EXEMPTION FROM REGISTRATION CLAIMED.

         Exemption for the original issuance of the shares of common stock which
may be offered or sold from time to time by the Selling Shareholders pursuant to
the reoffer prospectus contained in this registration statement is claimed under
Section 4(2) of the Securities Act.

ITEM 8.  EXHIBITS.

         The following exhibits are filed with or incorporated by reference into
this registration statement (numbering corresponds to exhibit table in Item 601
of Regulation S-K):

23.1     Consent of PricewaterhouseCoopers LLP

ITEM 9. UNDERTAKINGS.

(1)      The undersigned registrant hereby undertakes:

            (a)   To file, during any period in which offers or sales are being
                  made, a post-effective amendment to this registration
                  statement.

                                       19
(i)   To include any prospectus required by Section 10(a)(3)
                        of the Securities Act;

                  (ii)  To reflect in the prospectus any facts or events arising
                        after the effective date of this registration statement
                        (or the most recent post-effective amendment thereof)
                        which, individually or in the aggregate, represent a
                        fundamental change in the information set forth in this
                        registration statement.

                  (iii) To include any material information with respect to the
                        plan of distribution not previously disclosed in this
                        registration statement or any material change to such
                        information in this registration statement; provided,
                        however, that paragraphs (1)(a)(i) and (1)(a)(ii) do not
                        apply if the information required to be included in a
                        post-effective amendment by those paragraphs is
                        contained in periodic reports filed with or furnished to
                        the Commission by Cambrex pursuant to Section 13 or
                        Section 15(d) of the Exchange Act that are incorporated
                        by reference in this registration statement.

            (b)   That, for the purpose of determining any liability under the
                  Securities Act, each such post-effective amendment shall be
                  deemed to be a new registration statement relating to the
                  securities offered therein, and the offering of such
                  securities at that time shall be deemed to be the initial bona
                  fide offering thereof.

            (c)   To remove from registration by means of a post-effective
                  amendment any of the securities being registered which remain
                  unsold at the termination of the offering.

(2)  The undersigned registrant hereby undertakes that, for purposes of
     determining any liability under the Securities Act, each filing of
     Cambrex's annual report pursuant to Section 13(a) or Section 15(d) of the
     Exchange Act (and, where applicable, each filing of an employee benefit
     plan's annual report pursuant to Section 15(d) of the Exchange Act) that is
     incorporated by reference in this registration statement shall be deemed to
     be a new registration statement relating to the securities offered therein,
     and the offering of such securities at that time shall be deemed to be the
     initial bona fide offering thereof.

(3)  Insofar as indemnification for liabilities arising under the Securities Act
     may be permitted to directors, officers and controlling persons of Cambrex
     pursuant to the foregoing provisions, or otherwise, Cambrex has been
     advised that in the opinion of the Commission such indemnification is
     against public policy as expressed in the Securities Act and is, therefore,
     unenforceable. In the event that a claim for indemnification against such
     liabilities (other than the payment by Cambrex of expenses incurred or paid
     by a director, officer or controlling person of Cambrex in the successful
     defense of any action, suit or proceeding) is asserted by such director,
     officer or controlling person in connection with the securities being
     registered, Cambrex will, unless in the opinion of its counsel the matter
     has been settled by controlling precedent, submit to a court of appropriate
     jurisdiction the question whether such indemnification by it is against
     public policy as expressed in the Securities Act and will be governed by
     the final adjudication of such issue.

                                       20
SIGNATURES

         Pursuant to the requirements of the Securities Act, Cambrex certifies
that it has reasonable grounds to believe that it meets all of the requirements
for filing on Form S-8 and has duly caused this registration statement to be
signed on its behalf by the undersigned, thereunto duly authorized, in the City
of New York, on this 11th day of August, 2006.

CAMBREX CORPORATION

By:  /s/ Peter E. Thauer
-------------------------------------
Peter E. Thauer

Vice President - Law and Environment,
General Counsel and Secretary

                                       21
POWER OF ATTORNEY

         Each person whose signature appears below hereby severally constitutes
and appoints James A. Mack, Luke M. Beshar and Peter E. Thauer, and each of them
acting singly, as his or her true and lawful attorney-in-fact and agent, with
full and several power of substitution and resubstitution, to sign for him or
her and in his or her name, place and stead in any and all capacities indicated
below, the Registration Statement on Form S-8 filed herewith and any and all
pre-effective and post-effective amendments and supplements to the said
Registration Statement, and to file the same, with exhibits thereto and other
documents in connection therewith, with the Securities and Exchange Commission,
granting unto said attorney-in-fact and agent, full power and authority to do
and perform each and every act and thing requisite and necessary fully to all
intents and purposes as he or she might or could do in person hereby ratifying
and confirming all that said attorney-in-fact and agent, or his or her
substitute, may lawfully do or cause to be done by virtue hereof.

         Pursuant to the requirements of the Securities Act, this registration
statement has been signed below by the following persons in the capacities and
on the dates indicated:

Signature and Title                                     Date

/s/ James A. Mack                                       August 11, 2006
--------------------------------------
James A. Mack
President, Chief Executive Officer
and Chairman of the Board

/s/ Luke M. Beshar                                      August 11, 2006
--------------------------------------
Executive Vice President and
Chief Financial Officer

/s/ David R. Bethune                                    August 11, 2006
--------------------------------------
David R. Bethune
Director

                                       22
/s/ Rosina B. Dixon                                     August 11, 2006
--------------------------------------
Rosina B. Dixon
Director

/s/ Roy W. Haley                                        August 11, 2006
--------------------------------------
Roy W. Haley
Director

/s/ Kathryn R. Harrigan                                 August 11, 2006
--------------------------------------
Kathryn R. Harrigan, PhD
Director

/s/ Leon J. Hendrix, Jr.                                August 11, 2006
--------------------------------------
Leon J. Hendrix, Jr.
Director

/s/ Ilan Kaufthal                                       August 11, 2006
--------------------------------------
Ilan Kaufthal
Director

/s/ William B. Korb                                     August 11, 2006
--------------------------------------
William B. Korb
Director

/s/ John R. Miller                                      August 11, 2006
--------------------------------------
John R. Miller
Director

/s/ Peter G. Tombros                                    August 11, 2006
--------------------------------------
Peter G. Tombros
Director

                                       23