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<TITLE>TRANS1 INC.</TITLE>
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<H5 align="left" style="page-break-before:always"><A HREF="#tocpage">Table of Contents</A></H5><P>
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<DIV align="center" style="font-size: 10pt; margin-top: 18pt">As
filed with the Securities and Exchange Commission on August 6, 2009
</DIV>


<DIV align="right" style="font-size: 10pt; margin-top: 1pt">Registration No.&nbsp;333-
</DIV>


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<DIV style="width: 100%; border-bottom: 1pt solid black; font-size: 1pt">&nbsp;</DIV>




<DIV align="center" style="font-size: 14pt; margin-top: 8pt"><B>UNITED STATES<BR>
SECURITIES AND EXCHANGE COMMISSION</B>
</DIV>

<DIV align="center" style="font-size: 12pt"><B>Washington. D.C. 20549</B>
</DIV>

<DIV align="center" style="font-size: 12pt"><B><DIV align="center"><DIV style="font-size: 3pt; margin-top: 9pt; width: 26%; border-top: 1px solid #000000">&nbsp;</DIV></DIV></B>
</DIV>

<DIV align="center" style="font-size: 18pt; margin-top: 6pt"><B>FORM S-8</B>
</DIV>


<DIV align="center" style="font-size: 12pt; margin-top: 9pt"><B>REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933<BR>
<DIV align="center"><DIV style="font-size: 3pt; margin-top: 16pt; width: 26%; border-top: 1px solid #000000">&nbsp;</DIV></DIV></B>
</DIV>

<DIV align="center" style="font-size: 24pt; margin-top: 6pt"><B>TRANS1 INC.</B>
</DIV>

<DIV align="center" style="font-size: 10pt"><I>(Exact name of registrant as specified in its charter)</I></DIV>


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    <TD align="center" valign="top"><B>Delaware</B>
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top"><B>33-0909022</B></TD>
</TR>
<TR valign="bottom">
    <TD align="center" valign="top"><I>(State or other jurisdiction of</I>
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top"><I>(I.R.S. Employer Identification No.)</I></TD>
</TR>
<TR valign="bottom">
    <TD align="center" valign="top"><I>incorporation or organization)</I></TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">&nbsp;</TD>
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</DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 6pt"><B>411 Landmark Drive, Wilmington, North Carolina 28412-6303</B><BR>
<I>(Address of Principal Executive Offices)</I></DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 6pt"><DIV align="center"><DIV style="font-size: 3pt; margin-top: 9pt; width: 26%; border-top: 1px solid #000000">&nbsp;</DIV></DIV></DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 6pt"><B>2007 Stock Incentive Plan</B><BR>
<I>(Full title of the plans)</I></DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 6pt"><DIV align="center"><DIV style="font-size: 3pt; margin-top: 9pt; width: 26%; border-top: 1px solid #000000">&nbsp;</DIV></DIV></DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 6pt"><B>Richard Randall<BR>
President and Chief Executive Officer<BR>
TranS1 Inc.<BR>
411 Landmark Drive<BR>
Wilmington, NC 28412-6303</B><BR>
<I>(Name and address of agent for service)</I></DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 6pt"><B>(910)&nbsp;332-1700</B><BR>
<I>(Telephone number, including area code, of agent for service)</I></DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 6pt"><B>Copies to:<BR>
Bruce Feuchter, Esq.<BR>
Michael A. Hedge, Esq.<BR>
Stradling Yocca Carlson &#038; Rauth<BR>
660 Newport Center Drive, Suite&nbsp;1600<BR>
Newport Beach, California 92660<BR>
(949)&nbsp;725-4000</B><BR>
<DIV align="center"><DIV style="font-size: 3pt; margin-top: 9pt; width: 26%; border-top: 1px solid #000000">&nbsp;</DIV></DIV></DIV>








<DIV align="justify" style="font-size: 10pt; margin-top: 6pt; text-indent: 0%">Indicate by check mark whether the registrant is a large accelerated filer, an accelerated
filer, a non-accelerated filer, or a smaller reporting company. See the definitions of &#147;large
accelerated filer,&#148; &#147;accelerated filer&#148; and &#147;smaller reporting company&#148; in Rule&nbsp;12b-2 of the
Exchange Act. (Check one):
</DIV>



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    <TD width="3%">&nbsp;</TD>
    <TD width="22%">&nbsp;</TD>
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<TR valign="bottom">
    <TD align="center" valign="top">Large accelerated filer <FONT face="Wingdings">&#111;</FONT>
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">Accelerated filer <FONT face="Wingdings">&#254;</FONT>
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">Non-accelerated filer <FONT face="Wingdings">&#111;</FONT>
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top" nowrap>Smaller reporting company <FONT face="Wingdings">&#111;</FONT></TD>
</TR>
<TR valign="bottom">
    <TD align="center" valign="top">&nbsp;
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top" nowrap>(Do not check if a smaller reporting company)</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">&nbsp;</TD>
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<DIV align="center" style="font-size: 10pt; margin-top: 9pt"><B>CALCULATION OF REGISTRATION FEE</B>
</DIV>

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    <TD width="15%">&nbsp;</TD>
    <TD width="2%">&nbsp;</TD><!-- VRule -->
    <TD width="2%">&nbsp;</TD>
    <TD width="9%">&nbsp;</TD>

    <TD width="1%">&nbsp;</TD>
</TR><TR style="font-size: 1px" valign="bottom">
    <TD nowrap align="left" colspan="15" style="border-bottom: 3px double #000000">&nbsp;</TD>
</TR>
<TR style="font-size: 8pt" valign="bottom">    <TD width="1%">&nbsp;</TD>

    <TD>&nbsp;</TD>
    <TD style="border-right: 2px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD style="border-right: 2px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center"><B>Proposed Maximum</B></TD>
    <TD style="border-right: 2px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center"><B>Proposed Maximum</B></TD>
    <TD style="border-right: 2px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
</TR>
<TR style="font-size: 8pt" valign="bottom">    <TD width="1%">&nbsp;</TD>

    <TD nowrap align="center"><B>Title of Securities</B></TD>
    <TD style="border-right: 2px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center"><B>Amount to be</B></TD>
    <TD style="border-right: 2px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center"><B>Offering Price</B></TD>
    <TD style="border-right: 2px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center"><B>Aggregate Offering</B></TD>
    <TD style="border-right: 2px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center"><B>Amount Of</B></TD>
    <TD width="1%">&nbsp;</TD>
</TR>
<TR style="font-size: 8pt" valign="bottom">    <TD width="1%">&nbsp;</TD>

    <TD nowrap align="center"><B>to be Registered</B></TD>
    <TD style="border-right: 2px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center"><B>Registered (1)(2)</B></TD>
    <TD style="border-right: 2px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center"><B>Per Share</B></TD>
    <TD style="border-right: 2px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center"><B>Price (3)</B></TD>
    <TD style="border-right: 2px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center"><B>Registration Fee</B></TD>
    <TD width="1%">&nbsp;</TD>
</TR>

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    <TD width="1%" style="border-top: 2px solid #000000">&nbsp;</TD>
                    <TD style="border-top: 2px solid #000000"><DIV style="margin-left:15px; text-indent:-15px">Common Stock,
$0.0001 par value</DIV></TD>
    <TD style="border-right: 2px solid #000000; border-top: 2px solid #000000">&nbsp;</TD>
    <TD style="border-top: 2px solid #000000">&nbsp;</TD>
    <TD align="center" valign="top" style="border-top: 2px solid #000000">600,000 shares</TD>
    <TD style="border-right: 2px solid #000000; border-top: 2px solid #000000">&nbsp;</TD>
    <TD style="border-top: 2px solid #000000">&nbsp;</TD>

<TD align="center" valign="top" style="border-top: 2px solid #000000">$6.36</TD>
    <TD style="border-right: 2px solid #000000; border-top: 2px solid #000000">&nbsp;</TD>
    <TD style="border-top: 2px solid #000000">&nbsp;</TD>

<TD align="center" valign="top" style="border-top: 2px solid #000000">$3,816,000</TD>
    <TD style="border-right: 2px solid #000000; border-top: 2px solid #000000">&nbsp;</TD>
    <TD style="border-top: 2px solid #000000">&nbsp;</TD>

<TD align="center" valign="top" style="border-top: 2px solid #000000">$212.93</TD>
    <TD width="1%" style="border-top: 2px solid #000000">&nbsp;</TD>
</TR>
<TR style="font-size: 1px" valign="bottom">
    <TD nowrap align="left" colspan="15" style="border-top: 3px double #000000">&nbsp;</TD>
</TR>

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<DIV align="left">
<DIV style="font-size: 3pt; margin-top: 1pt; width: 18%; border-top: 0px solid #000000">&nbsp;</DIV>
</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
<TR>
    <TD width="3%"></TD>
    <TD width="1%"></TD>
    <TD width="96"></TD>
</TR>

<TR valign="top">
    <TD nowrap align="left">(1)</TD>
    <TD>&nbsp;</TD>
    <TD>Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the &#147;Securities Act&#148;),
this registration statement also covers any additional shares of common stock, par value
$0.0001 per share (the &#147;Common Stock&#148;) of TranS1 Inc. that may become issuable under our 2007
Stock Incentive Plan, as such may be amended from time to time (the &#147;2007 Plan&#148;), by reason of
any stock dividend, stock split, recapitalization or other similar transaction effected
without the receipt of consideration that results in an increase in the number of outstanding
shares of our Common Stock.</TD>
</TR>

<TR style="font-size: 3pt"><TD>&nbsp;</TD></TR>

<TR valign="top">
    <TD nowrap align="left">(2)</TD>
    <TD>&nbsp;</TD>
    <TD>This amount represents the additional shares of Common Stock eligible to be issued under the
2007 Plan. An aggregate of 1,400,000 shares of Common Stock available for issuance under the
2007 Plan have previously been registered on a registration statement on Form S-8 filed on
November&nbsp;7, 2007 (Registration No.&nbsp;333-147219).</TD>
</TR>

<TR style="font-size: 3pt"><TD>&nbsp;</TD></TR>

<TR valign="top">
    <TD nowrap align="left">(3)</TD>
    <TD>&nbsp;</TD>
    <TD>In accordance with Rule 457(h) under the Securities Act, the aggregate offering price is
estimated, solely for purposes of calculating the registration fee, on the basis of the price
of our Common Stock, as determined in accordance with Rule 457(c) under the Securities Act,
using the average of the high and low prices (rounded to the nearest cent) reported on The
NASDAQ Global Market on July&nbsp;31, 2009.</TD>
</TR>

</TABLE>



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<DIV style="width: 100%; border-bottom: 2pt solid black; font-size: 1pt">&nbsp;</DIV>






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<A name="tocpage"></A>

<DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>TABLE OF CONTENTS</B></DIV>

<DIV align="center">
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    <TD width="90%">&nbsp;</TD>
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<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px"><A href="#101"><B>EXPLANATORY NOTE</B></A></DIV></TD>
<TD width="10%" align="right">&nbsp;</TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD><DIV style="margin-left:15px; text-indent:-15px">&nbsp;</DIV></TD>
<TD width="10%" align="right">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px"><A href="#102"><B>PART I</B></A></DIV></TD>
<TD width="10%" align="right">4</TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD><DIV style="margin-left:15px; text-indent:-15px">&nbsp;</DIV></TD>
<TD width="10%" align="right">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px"><A href="#103"><B>PART II</B></A></DIV></TD>
<TD width="10%" align="right">4</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</DIV></TD>
<TD width="10%" align="right">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:30px; text-indent:-15px"><A href="#104">Item&nbsp;3. Incorporation of Documents by Reference.</A></DIV></TD>
<TD width="10%" align="right">4</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:30px; text-indent:-15px"><A href="#105">Item&nbsp;4. Description of Securities.</A></DIV></TD>
<TD width="10%" align="right">4</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:30px; text-indent:-15px"><A href="#106">Item&nbsp;5. Interests of Named Experts and Counsel.</A></DIV></TD>
<TD width="10%" align="right">4</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:30px; text-indent:-15px"><A href="#107">Item&nbsp;6. Indemnification of Directors and Officers.</A></DIV></TD>
<TD width="10%" align="right">5</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:30px; text-indent:-15px"><A href="#108">Item&nbsp;7. Exemption from Registration Claimed.</A></DIV></TD>
<TD width="10%" align="right">6</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:30px; text-indent:-15px"><A href="#109">Item&nbsp;8. Exhibits.</A></DIV></TD>
<TD width="10%" align="right">6</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:30px; text-indent:-15px"><A href="#110">Item&nbsp;9. Undertakings.</A></DIV></TD>
<TD width="10%" align="right">6</TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD><DIV style="margin-left:15px; text-indent:-15px">&nbsp;</DIV></TD>
<TD width="10%" align="right">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px"><A href="#111"><B>SIGNATURES</B></A></DIV></TD>
<TD width="10%" align="right">8</TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD><DIV style="margin-left:15px; text-indent:-15px">&nbsp;</DIV></TD>
<TD width="10%" align="right">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px"><A href="#112"><B>EXHIBIT INDEX</B></A></DIV></TD>
<TD width="10%" align="right">&nbsp;</TD>
</TR>
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<TR><TD colspan="9"><FONT size="2">&nbsp;<A HREF="g19750exv5w1.htm">EX-5.1 OPINION OF STRADLING YOCCA CARLSON & RAUTH</A></FONT></TD></TR>
<TR><TD colspan="9"><FONT size="2">&nbsp;<A HREF="g19750exv23w1.htm">EX-23.1 CONSENT OF PRICEWATERHOUSECOOPERS LLP</A></FONT></TD></TR>
</TABLE></DIV>

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<H5 align="left" style="page-break-before:always"><A HREF="#tocpage">Table of Contents</A></H5><P>

<DIV style="font-family: 'Times New Roman',Times,serif">

<DIV align="left">
<A name="101"></A>
</DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>EXPLANATORY NOTE</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;This Registration Statement has been prepared in accordance with General Instruction E to Form
S-8 and relates to an increase of 600,000 shares of common stock, par value $0.0001 per share (the
&#147;Common Stock&#148;) of TranS1 Inc. (referred to herein as &#147;our,&#148; &#147;we&#148; or &#147;us&#148;) available for issuance
under its 2007 Stock Incentive Plan, as such may be amended from time to time (the &#147;2007 Plan&#148;).
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;On April&nbsp;23, 2009, our Board of Directors approved and adopted an amendment to the 2007 Plan,
which, among other things, increases the number of shares of Common Stock available for issuance
under the 2007 Plan by 600,000 shares from 1,400,000 shares to 2,000,000 shares. The amendment was
approved by our stockholders at our 2009 Annual Meeting of Stockholders, which was held on June&nbsp;3,
2009.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Each of the 1,400,000 shares of Common Stock previously made available for issuance under the
2007 Plan have been registered with the Securities and Exchange Commission (the &#147;Commission&#148;) on a
Registration Statement on Form S-8 filed with the Commission on November&nbsp;7, 2007 (Registration No.
333-147219).
</DIV>


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</DIV>

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<H5 align="left" style="page-break-before:always"><A HREF="#tocpage">Table of Contents</A></H5><P>

<DIV style="font-family: 'Times New Roman',Times,serif">



<DIV align="left">
<A name="102"></A>
</DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>PART I<BR>
INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;In accordance with Rule 428(b) under the Securities Act of 1933, as amended (the &#147;Securities
Act&#148;), the documents containing the information called for by Part&nbsp;I of Form S-8 will be sent or
given to individuals who participate in the 2007 Plan and are not being filed with or included in
this Form S-8.
</DIV>
<DIV align="left">
<A name="103"></A>
</DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>PART II<BR>
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</B>
</DIV>

<DIV align="left">
<A name="104"></A>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 12pt">Item&nbsp;3. <U>Incorporation of Documents by Reference</U>.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The following documents which have been, or will in the future be, filed by us with the
Commission are incorporated herein by this reference:
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(1)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Our Annual Report on Form 10-K for the fiscal year ended December&nbsp;31, 2008, as
filed with the Commission on March&nbsp;13, 2009.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(2)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Our Quarterly Report on Form 10-Q for the fiscal quarter ended March&nbsp;31, 2009,
as filed with the Commission on May&nbsp;6, 2009.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(3)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Our Current Reports on Form 8-K, as filed with the Commission
on April&nbsp;30, 2009, June&nbsp;4, 2009, July&nbsp;14, 2009 and
August&nbsp;3, 2009.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(4)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Our Definitive Proxy Statement on Schedule&nbsp;14A, as filed with the Commission on
April&nbsp;30, 2009.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(5)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The description of our Common Stock contained in our Registration Statement on
Form 8-A (File No.&nbsp;001-33744) filed with the Commission on October&nbsp;15, 2007 pursuant to
Section 12(b) of the Securities Exchange Act of 1934, as amended (the &#147;Exchange Act&#148;),
including any amendment or report filed for the purpose of updating such description.</TD>
</TR>

</TABLE>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Information furnished to the Commission under Item&nbsp;2.02 or Item&nbsp;7.01 in Current Reports on
Form 8-K, and any exhibit relating to such information, filed prior to, on or subsequent to the
date of this Registration Statement, is not incorporated by reference into this Registration
Statement.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;All documents subsequently filed by us pursuant to Sections&nbsp;13(a), 13(c), 14 and 15(d) of the
Exchange Act, prior to the filing of a post-effective amendment which indicates that all securities
offered have been sold or which deregisters all of such securities then remaining unsold, shall be
deemed to be incorporated by reference in this Registration Statement and to be a part hereof from
the date of filing of such documents, except as to any portion of any future annual or quarterly
report to stockholders, or document that is not deemed filed under such provisions. For the
purposes of this Registration Statement, any statement in a document incorporated by reference
shall be deemed to be modified or superseded to the extent that a statement contained in this
Registration Statement modifies or supersedes a statement in such document. Any statement so
modified or superseded shall not be deemed, except as so modified or superseded, to constitute a
part of this Registration Statement.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The contents of our Registration Statement on Form S-8 (Registration No.&nbsp;333-147219) is
incorporated herein by reference.
</DIV>
<DIV align="left">
<A name="105"></A>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 12pt">Item&nbsp;4. <U>Description of Securities</U>.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not applicable.
</DIV>
<DIV align="left">
<A name="106"></A>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 12pt">Item&nbsp;5. <U>Interests of Named Experts and Counsel</U>.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The validity of the Common Stock offered hereby will be passed upon for us by Stradling Yocca
Carlson &#038; Rauth, a Professional Corporation, Newport Beach, California. As of the date of this
Registration Statement, certain attorneys of Stradling Yocca Carlson &#038; Rauth hold an aggregate of
248,113 shares of our outstanding Common Stock.
</DIV>

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</DIV>

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<DIV style="font-family: 'Times New Roman',Times,serif">
<DIV align="left">
<A name="107"></A>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 12pt">Item&nbsp;6. <U>Indemnification of Directors and Officers</U>.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Section&nbsp;145(a) of the Delaware General Corporation Law (&#147;DGCL&#148;) provides that a Delaware
corporation may indemnify any person who was or is, or is threatened to be made, a party to any
threatened, pending or completed action, suit or proceeding, whether civil, criminal,
administrative or investigative (other than an action by or in the right of such corporation), by
reason of the fact that such person was an officer, director, employee or agent of such
corporation, or is or was serving at the request of such person as an officer, director, employee
or agent of another corporation or enterprise. The indemnity may include expenses (including
attorneys&#146; fees), judgments, fines and amounts paid in settlement actually and reasonably incurred
by such person in connection with such action, suit or proceeding, provided that such person acted
in good faith and in a manner he or she reasonably believed to be in or not opposed to the
corporation&#146;s best interests and, with respect to any criminal action or proceeding, had no
reasonable cause to believe that his or her conduct was illegal. With respect to derivative
actions, Section 145(b) of the DGCL provides in relevant part that a corporation may indemnify any
person who was or is a party or is threatened to be made a party to any threatened, pending or
completed action or suit by or in the right of the corporation to procure a judgment in its favor
by reason of the fact that such person was or is a director, officer, employee or agent of such
corporation, or is or was serving at the request of such corporation as a director, officer,
employee or agent of another corporation or enterprise against expenses (including attorneys&#146; fees)
actually and reasonably incurred by the person in connection with the defense or settlement of such
action or suit if the person acted in good faith and in a manner the person reasonably believed to
be in or not opposed to the best interests of the corporation and except that no indemnification
shall be made in respect of any claim, issue or matter as to which such person shall have been
adjudged to be liable to the corporation unless and only to the extent that the Court of Chancery
or the court in which such action or suit was brought shall determine upon application that,
despite the adjudication of liability but in view of all the circumstances of the case, such person
is fairly and reasonably entitled to indemnity for such expenses which the Court of Chancery or
such other court shall deem proper. Section 145(c) of the DGCL provides that where an officer or
director is successful on the merits or otherwise in the defense of any action referred to above,
the corporation must indemnify him or her against the expenses (including attorneys&#146; fees) which
such officer or director has actually and reasonably incurred.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Our amended and restated certificate of incorporation provides that to the fullest extent
permitted by applicable law, we are authorized to provide indemnification of (and advancement of
expenses to) our directors, officers, employees and agents (and any other persons to whom Delaware
law permits us to provide indemnification) through bylaw provisions, agreements with such agents or
other persons, vote of stockholders or disinterested directors or otherwise, in excess of the
indemnification and advancement otherwise permitted by Section&nbsp;145 of the DGCL, subject only to
limits created by applicable Delaware law (statutory or non-statutory), with respect to actions for
breach of duty to a corporation, its stockholders and others. Our amended and restated bylaws
provide for the indemnification of our directors and officers to the fullest extent permitted under
the DGCL against all expense, liability and loss (including attorneys&#146; fees, judgments, fines,
ERISA excise taxes or penalties and amounts paid in settlement) reasonably incurred or suffered by
such director or officer. Our amended and restated bylaws also provide for the advancement of
expenses incurred in defending any such proceeding in advance of its final disposition, subject to
any requirement of the DGCL regarding the delivery to us of an undertaking, by or on behalf of such
director or officer, to repay all amounts so advanced if it shall ultimately be determined by final
judicial decision from which there is no further right to appeal that such director or officer is
not entitled to be indemnified for such expenses incurred.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;We have also entered into an indemnification agreement with each of our directors and certain
of our executive officers providing for indemnification to the fullest extent permitted by the
DGCL.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Section&nbsp;102(b)(7) of the DGCL permits a corporation to include in its certificate of
incorporation a provision to the effect that a director of the corporation shall not be personally
liable to the corporation or its stockholders for monetary damages for breach of fiduciary duties
as a director, except for liability for any (i)&nbsp;breach of a director&#146;s duty of loyalty to the
corporation or its stockholders, (ii)&nbsp;act or omission not in good faith or that involves
intentional misconduct or a knowing violation of law, (iii)&nbsp;unlawful payment of dividends or
redemption of shares, or (iv)&nbsp;transaction from which the director derives an improper personal
benefit. Our amended and restated certificate of incorporation includes such a provision.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Our amended and restated bylaws provide that we may maintain insurance, at our expense, to
protect us and any director, officer, employee or agent of TranS1 or another corporation,
partnership, joint venture, trust or other enterprise against any expense, liability or loss,
whether or not we would have the power to indemnify such person against such expense, liability or
loss under the DGCL. We have an insurance policy covering our directors and officers
</DIV>

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<DIV style="font-family: 'Times New Roman',Times,serif">



<DIV align="left" style="font-size: 10pt; margin-top: 6pt">with respect
to certain liabilities, including liabilities arising under the Securities Act, which might be
incurred by them
in such capacities and against which they cannot be indemnified by us.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The indemnification provisions set forth above and the indemnification agreements entered into
between us and our directors and certain of our officers may be sufficiently broad to permit
indemnification of our directors and officers for liabilities (including reimbursement of expenses
incurred) arising under the Securities Act. The foregoing statements are subject to the detailed
provisions of the DGCL and to the applicable provisions of our amended and restated certificate of
incorporation and amended and restated bylaws.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;At present, there is no pending litigation or proceeding involving any of our directors or
executive officers as to which indemnification is required or permitted, and we are not aware of
any threatened litigation or proceeding that may result in a claim for indemnification.
</DIV>
<DIV align="left">
<A name="108"></A>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 12pt">Item&nbsp;7. <U>Exemption from Registration Claimed</U>.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not applicable.
</DIV>
<DIV align="left">
<A name="109"></A>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 12pt">Item&nbsp;8. <U>Exhibits.</U>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;See Exhibit&nbsp;Index below.
</DIV>
<DIV align="left">
<A name="110"></A>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 12pt"><U>Item&nbsp;9. Undertakings</U>.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a)&nbsp;We hereby undertake:
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1. To file, during any period in which offers or sales are being made, a post-effective
amendment to this registration statement:
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;i.&nbsp;To include any prospectus required by section 10(a)(3) of the Securities Act of 1933;
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;ii.&nbsp;To reflect in the prospectus any facts or events arising after the effective date of the
registration statement (or the most recent post-effective amendment thereof) which, individually or
in the aggregate, represent a fundamental change in the information set forth in the registration
statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered
(if the total dollar value of securities offered would not exceed that which was registered) and
any deviation from the low or high end of the estimated maximum offering range may be reflected in
the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the
changes in volume and price represent no more than a 20% change in the maximum aggregate offering
price set forth in the &#147;Calculation of Registration Fee&#148; table in the effective registration
statement.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;iii.&nbsp;To include any material information with respect to the plan of distribution not
previously disclosed in the registration statement or any material change to such information in
the registration statement;
</DIV>
<DIV align="left" style="font-size: 10pt; margin-top: 6pt"><I>Provided, however</I>, that paragraphs (a)(1)(i) and (a)(1)(ii) above do not apply if the information
required to be included in a post-effective amendment by those paragraphs is contained in periodic
reports filed with or furnished to the Commission by us pursuant to Section&nbsp;13 or 15(d) of the
Exchange Act that are incorporated by reference in this registration statement.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2. That, for the purpose of determining any liability under the Securities Act of 1933, each
such post-effective amendment shall be deemed to be a new registration statement relating to the
securities offered therein, and the offering of such securities at that time shall be deemed to be
the initial bona fide offering thereof.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3. To remove from registration by means of a post-effective amendment any of the securities
being registered which remain unsold at the termination of the offering.
</DIV>


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<DIV style="font-family: 'Times New Roman',Times,serif">




<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b)&nbsp;We hereby undertake that, for purposes of determining any liability under the Securities
Act, each filing of our annual report pursuant to Section 13(a) or Section 15(d) of the Exchange
Act that is incorporated by reference in the registration statement shall be deemed to be a new
registration statement relating to the securities offered therein, and the offering of such
securities at that time shall be deemed to be the initial bona fide offering thereof.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c)&nbsp;Insofar as indemnification for liabilities arising under the Securities Act may be
permitted to directors, officers and controlling persons of the registrant pursuant to the
foregoing provisions, or otherwise, the registrant has been advised that in the opinion of the
Securities and Exchange Commission such indemnification is against public policy as expressed in
the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification
against such liabilities (other than the payment by the registrant of expenses incurred or paid by
a director, officer or controlling person of the registrant in the successful defense of any
action, suit or proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the registrant will, unless in the opinion of its
counsel the matter has been settled by controlling precedent, submit to a court of appropriate
jurisdiction the question whether such indemnification by it is against public policy as expressed
in the Securities Act and will be governed by the final adjudication of such issue.
</DIV>


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<DIV style="font-family: 'Times New Roman',Times,serif">



<DIV align="left">
<A name="111"></A>
</DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>SIGNATURES</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act of 1933, as amended, TranS1 Inc., the
registrant, certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form S-8 and has duly caused this registration statement to be signed on
its behalf by the undersigned, thereunto duly authorized, in the City of Wilmington, State of North
Carolina, on the 6th day of August, 2009.
</DIV>

<TABLE width="100%" border="0" cellspacing="0" cellpadding="0" style="font-size: 10pt">
<TR>
    <TD width="48%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="35%">&nbsp;</TD>
    <TD width="15%">&nbsp;</TD>
</TR>
<TR>
    <TD valign="top" align="left">&nbsp;</TD>
    <TD colspan="3" align="left">TRANS1 INC.<BR>
&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">&nbsp;</TD>
    <TD valign="top">By:&nbsp;&nbsp;</TD>
    <TD colspan="2" style="border-bottom: 1px solid #000000" align="left">/s/ Richard Randall
&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD colspan="2" align="left">Richard Randall&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD colspan="2" align="left">President and Chief Executive Officer&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR>
    <TD colspan="5">&nbsp;</TD>
</TR>
</TABLE>

<DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>POWER OF ATTORNEY</B>
</DIV>



<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;We, the undersigned directors and officers of TranS1 Inc., do hereby constitute and appoint
Richard Randall and Michael Luetkemeyer or either of them, our true and lawful attorneys and
agents, to do any and all acts and things in our name and behalf in our capacities as directors and
officers and to execute any and all instruments for us and in our names in the capacities indicated
below, which said attorneys and agents, or either of them, may deem necessary or advisable to
enable said corporation to comply with the Securities Act of 1933, as amended, and any rules,
regulations, and requirements of the Securities and Exchange Commission, in connection with this
registration statement, including specifically, but without limitation, power and authority to sign
for us or any of us in our names and in the capacities indicated below, any and all amendments
(including post-effective amendments) to this registration statement and we do hereby ratify and
confirm all that the said attorneys and agents, or either of them, shall do or cause to be done by
virtue hereof.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to the requirements of the Securities Act of 1933, as amended, this registration
statement has been signed below by the following persons in the capacities and on the dates
indicated.
</DIV>
<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="40%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="40%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="14%">&nbsp;</TD>
</TR>
<TR style="font-size: 8pt" valign="bottom">
    <TD nowrap align="center" style="border-bottom: 1px solid #000000">Signature</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" style="border-bottom: 1px solid #000000">Title</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" style="border-bottom: 1px solid #000000">Date</TD>
</TR>

<!-- End Table Head -->
<!-- Begin Table Body -->
<TR>
        <TD>&nbsp;<BR></TD>
</TR>
<TR valign="bottom">
    <TD align="left" valign="top"><DIV style="margin-left:0px; text-indent:-0px">/s/ Richard Randall
<DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
Richard Randall</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">
President, Chief Executive
Officer and Director<br>
(Principal Executive Officer)
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">August 6, 2009</TD>
</TR>
<TR valign="bottom" style="padding-top: 1em">
    <TD align="left" valign="top">/s/ Michael Luetkemeyer
<DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
Michael Luetkemeyer</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">
Chief Financial Officer
(Principal Financial and
Accounting Officer)
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">August 6, 2009</TD>
</TR>
<TR valign="bottom" style="padding-top: 1em">
    <TD align="left" valign="top">/s/ Michael Carusi
<DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
Michael Carusi</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">
Director
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">August 6, 2009</TD>
</TR>
<TR valign="bottom" style="padding-top: 1em">
    <TD align="left" valign="top">/s/ Mitchell Dann
<DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
Mitchell Dann</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">
Director
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">August 6, 2009</TD>
</TR>
<TR valign="bottom" style="padding-top: 1em">
    <TD align="left" valign="top">/s/ Paul LaViolette
<DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
Paul LaViolette</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">
Director
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">August 6, 2009</TD>
</TR>
<TR valign="bottom" style="padding-top: 1em">
    <TD align="left" valign="top">/s/ Jonathan Osgood
<DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
Jonathan Osgood</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">
Director
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">August 6, 2009</TD>
</TR>

<TR valign="bottom" style="padding-top: 1em">
    <TD align="left" valign="top">&nbsp;
<DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
James Shapiro</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">
Director
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom" style="padding-top: 1em">
    <TD align="left" valign="top">/s/ Joseph Slattery
<DIV style="font-size: 1pt; border-bottom: 1px solid #000000">&nbsp;</DIV>
Joseph Slattery</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">
Director
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">August 6, 2009</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>





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<DIV style="font-family: 'Times New Roman',Times,serif">



<DIV align="left">
<A name="112"></A>
</DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>EXHIBIT INDEX</B>
</DIV>

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="7%">&nbsp;</TD>
    <TD width="2%">&nbsp;</TD>
    <TD width="91%">&nbsp;</TD>
</TR>
<TR style="font-size: 8pt" valign="bottom">
    <TD nowrap align="left" style="border-bottom: 1px solid #000000">Number</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="left" style="border-bottom: 1px solid #000000">Description</TD>
</TR>

<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom"><!-- Blank Space -->
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">4.1
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Specimen Common Stock certificate (incorporated by
reference to Exhibit&nbsp;4.1 to the Registration Statement on
Form&nbsp;S-1, as amended (File No.&nbsp;333-144802), and as declared
effective on October&nbsp;16, 2007).</TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">4.2
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Amended and Restated Certificate of Incorporation
of TranS1 Inc. (incorporated by reference to Exhibit&nbsp;3.2 to
the Registration Statement on Form&nbsp;S-1, as amended (File No.
333-144802), and as declared effective on October&nbsp;16, 2007).</TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">4.3
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Amended and Restated Bylaws of TranS1 Inc.
(incorporated by reference to Exhibit&nbsp;3.4 to the Registration
Statement on <FONT style="white-space: nowrap">Form&nbsp;S-1,</FONT> as amended (File No.&nbsp;333-144802), and
as declared effective on October&nbsp;16, 2007).</TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">5.1
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Opinion of Stradling Yocca Carlson &#038; Rauth, a
Professional Corporation.</TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">23.1
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Consent of PricewaterhouseCoopers LLP, Independent
Registered Public Accounting Firm.</TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">23.2
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Consent of Stradling Yocca Carlson &#038; Rauth, a
Professional Corporation (included in Exhibit&nbsp;5.1 hereto).</TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">24.1
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Power of Attorney (included on signature page to the
Registration Statement).</TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">99.1
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">TranS1 Inc. 2007 Stock Incentive Plan, as amended
(incorporated by reference to Appendix&nbsp;A to the Definitive
Proxy Statement on Schedule&nbsp;14A, as filed with the Commission
on April&nbsp;30, 2009).</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>


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TRANS1 INC.
Table of Contents
As
filed with the Securities and Exchange Commission on August 6, 2009
Registration No. 333-
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington. D.C. 20549
FORM S-8
REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933
TRANS1 INC.
(Exact name of registrant as specified in its charter)
Delaware
33-0909022
(State or other jurisdiction of
(I.R.S. Employer Identification No.)
incorporation or organization)
411 Landmark Drive, Wilmington, North Carolina 28412-6303
(Address of Principal Executive Offices)
2007 Stock Incentive Plan
(Full title of the plans)
Richard Randall
President and Chief Executive Officer
TranS1 Inc.
411 Landmark Drive
Wilmington, NC 28412-6303
(Name and address of agent for service)
(910) 332-1700
(Telephone number, including area code, of agent for service)
Copies to:
Bruce Feuchter, Esq.
Michael A. Hedge, Esq.
Stradling Yocca Carlson & Rauth
660 Newport Center Drive, Suite 1600
Newport Beach, California 92660
(949) 725-4000
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated
filer, a non-accelerated filer, or a smaller reporting company. See the definitions of "large
accelerated filer," "accelerated filer" and "smaller reporting company" in Rule 12b-2 of the
Exchange Act. (Check one):
Large accelerated filer
o
Accelerated filer
þ
Non-accelerated filer
o
Smaller reporting company
o
(Do not check if a smaller reporting company)
CALCULATION OF REGISTRATION FEE
Proposed Maximum
Proposed Maximum
Title of Securities
Amount to be
Offering Price
Aggregate Offering
Amount Of
to be Registered
Registered (1)(2)
Per Share
Price (3)
Registration Fee
Common Stock,
$0.0001 par value
600,000 shares
$6.36
$3,816,000
$212.93
(1)
Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the "Securities Act"),
this registration statement also covers any additional shares of common stock, par value
$0.0001 per share (the "Common Stock") of TranS1 Inc. that may become issuable under our 2007
Stock Incentive Plan, as such may be amended from time to time (the "2007 Plan"), by reason of
any stock dividend, stock split, recapitalization or other similar transaction effected
without the receipt of consideration that results in an increase in the number of outstanding
shares of our Common Stock.
(2)
This amount represents the additional shares of Common Stock eligible to be issued under the
2007 Plan. An aggregate of 1,400,000 shares of Common Stock available for issuance under the
2007 Plan have previously been registered on a registration statement on Form S-8 filed on
November 7, 2007 (Registration No. 333-147219).
(3)
In accordance with Rule 457(h) under the Securities Act, the aggregate offering price is
estimated, solely for purposes of calculating the registration fee, on the basis of the price
of our Common Stock, as determined in accordance with Rule 457(c) under the Securities Act,
using the average of the high and low prices (rounded to the nearest cent) reported on The
NASDAQ Global Market on July 31, 2009.
TABLE OF CONTENTS
EXPLANATORY NOTE
PART I
4
PART II
4
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 3. Incorporation of Documents by Reference.
4
Item 4. Description of Securities.
4
Item 5. Interests of Named Experts and Counsel.
4
Item 6. Indemnification of Directors and Officers.
5
Item 7. Exemption from Registration Claimed.
6
Item 8. Exhibits.
6
Item 9. Undertakings.
6
SIGNATURES
8
EXHIBIT INDEX
EX-5.1 OPINION OF STRADLING YOCCA CARLSON & RAUTH
EX-23.1 CONSENT OF PRICEWATERHOUSECOOPERS LLP
Table of Contents
EXPLANATORY NOTE
This Registration Statement has been prepared in accordance with General Instruction E to Form
S-8 and relates to an increase of 600,000 shares of common stock, par value $0.0001 per share (the
"Common Stock") of TranS1 Inc. (referred to herein as "our," "we" or "us") available for issuance
under its 2007 Stock Incentive Plan, as such may be amended from time to time (the "2007 Plan").
On April 23, 2009, our Board of Directors approved and adopted an amendment to the 2007 Plan,
which, among other things, increases the number of shares of Common Stock available for issuance
under the 2007 Plan by 600,000 shares from 1,400,000 shares to 2,000,000 shares. The amendment was
approved by our stockholders at our 2009 Annual Meeting of Stockholders, which was held on June 3,
2009.
Each of the 1,400,000 shares of Common Stock previously made available for issuance under the
2007 Plan have been registered with the Securities and Exchange Commission (the "Commission") on a
Registration Statement on Form S-8 filed with the Commission on November 7, 2007 (Registration No.
333-147219).
Table of Contents
PART I
INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS
In accordance with Rule 428(b) under the Securities Act of 1933, as amended (the "Securities
Act"), the documents containing the information called for by Part I of Form S-8 will be sent or
given to individuals who participate in the 2007 Plan and are not being filed with or included in
this Form S-8.
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 3.
Incorporation of Documents by Reference
.
The following documents which have been, or will in the future be, filed by us with the
Commission are incorporated herein by this reference:
(1)
Our Annual Report on Form 10-K for the fiscal year ended December 31, 2008, as
filed with the Commission on March 13, 2009.
(2)
Our Quarterly Report on Form 10-Q for the fiscal quarter ended March 31, 2009,
as filed with the Commission on May 6, 2009.
(3)
Our Current Reports on Form 8-K, as filed with the Commission
on April 30, 2009, June 4, 2009, July 14, 2009 and
August 3, 2009.
(4)
Our Definitive Proxy Statement on Schedule 14A, as filed with the Commission on
April 30, 2009.
(5)
The description of our Common Stock contained in our Registration Statement on
Form 8-A (File No. 001-33744) filed with the Commission on October 15, 2007 pursuant to
Section 12(b) of the Securities Exchange Act of 1934, as amended (the "Exchange Act"),
including any amendment or report filed for the purpose of updating such description.
Information furnished to the Commission under Item 2.02 or Item 7.01 in Current Reports on
Form 8-K, and any exhibit relating to such information, filed prior to, on or subsequent to the
date of this Registration Statement, is not incorporated by reference into this Registration
Statement.
All documents subsequently filed by us pursuant to Sections 13(a), 13(c), 14 and 15(d) of the
Exchange Act, prior to the filing of a post-effective amendment which indicates that all securities
offered have been sold or which deregisters all of such securities then remaining unsold, shall be
deemed to be incorporated by reference in this Registration Statement and to be a part hereof from
the date of filing of such documents, except as to any portion of any future annual or quarterly
report to stockholders, or document that is not deemed filed under such provisions. For the
purposes of this Registration Statement, any statement in a document incorporated by reference
shall be deemed to be modified or superseded to the extent that a statement contained in this
Registration Statement modifies or supersedes a statement in such document. Any statement so
modified or superseded shall not be deemed, except as so modified or superseded, to constitute a
part of this Registration Statement.
The contents of our Registration Statement on Form S-8 (Registration No. 333-147219) is
incorporated herein by reference.
Item 4.
Description of Securities
.
Not applicable.
Item 5.
Interests of Named Experts and Counsel
.
The validity of the Common Stock offered hereby will be passed upon for us by Stradling Yocca
Carlson & Rauth, a Professional Corporation, Newport Beach, California. As of the date of this
Registration Statement, certain attorneys of Stradling Yocca Carlson & Rauth hold an aggregate of
248,113 shares of our outstanding Common Stock.
4
Table of Contents
Item 6.
Indemnification of Directors and Officers
.
Section 145(a) of the Delaware General Corporation Law ("DGCL") provides that a Delaware
corporation may indemnify any person who was or is, or is threatened to be made, a party to any
threatened, pending or completed action, suit or proceeding, whether civil, criminal,
administrative or investigative (other than an action by or in the right of such corporation), by
reason of the fact that such person was an officer, director, employee or agent of such
corporation, or is or was serving at the request of such person as an officer, director, employee
or agent of another corporation or enterprise. The indemnity may include expenses (including
attorneys' fees), judgments, fines and amounts paid in settlement actually and reasonably incurred
by such person in connection with such action, suit or proceeding, provided that such person acted
in good faith and in a manner he or she reasonably believed to be in or not opposed to the
corporation's best interests and, with respect to any criminal action or proceeding, had no
reasonable cause to believe that his or her conduct was illegal. With respect to derivative
actions, Section 145(b) of the DGCL provides in relevant part that a corporation may indemnify any
person who was or is a party or is threatened to be made a party to any threatened, pending or
completed action or suit by or in the right of the corporation to procure a judgment in its favor
by reason of the fact that such person was or is a director, officer, employee or agent of such
corporation, or is or was serving at the request of such corporation as a director, officer,
employee or agent of another corporation or enterprise against expenses (including attorneys' fees)
actually and reasonably incurred by the person in connection with the defense or settlement of such
action or suit if the person acted in good faith and in a manner the person reasonably believed to
be in or not opposed to the best interests of the corporation and except that no indemnification
shall be made in respect of any claim, issue or matter as to which such person shall have been
adjudged to be liable to the corporation unless and only to the extent that the Court of Chancery
or the court in which such action or suit was brought shall determine upon application that,
despite the adjudication of liability but in view of all the circumstances of the case, such person
is fairly and reasonably entitled to indemnity for such expenses which the Court of Chancery or
such other court shall deem proper. Section 145(c) of the DGCL provides that where an officer or
director is successful on the merits or otherwise in the defense of any action referred to above,
the corporation must indemnify him or her against the expenses (including attorneys' fees) which
such officer or director has actually and reasonably incurred.
Our amended and restated certificate of incorporation provides that to the fullest extent
permitted by applicable law, we are authorized to provide indemnification of (and advancement of
expenses to) our directors, officers, employees and agents (and any other persons to whom Delaware
law permits us to provide indemnification) through bylaw provisions, agreements with such agents or
other persons, vote of stockholders or disinterested directors or otherwise, in excess of the
indemnification and advancement otherwise permitted by Section 145 of the DGCL, subject only to
limits created by applicable Delaware law (statutory or non-statutory), with respect to actions for
breach of duty to a corporation, its stockholders and others. Our amended and restated bylaws
provide for the indemnification of our directors and officers to the fullest extent permitted under
the DGCL against all expense, liability and loss (including attorneys' fees, judgments, fines,
ERISA excise taxes or penalties and amounts paid in settlement) reasonably incurred or suffered by
such director or officer. Our amended and restated bylaws also provide for the advancement of
expenses incurred in defending any such proceeding in advance of its final disposition, subject to
any requirement of the DGCL regarding the delivery to us of an undertaking, by or on behalf of such
director or officer, to repay all amounts so advanced if it shall ultimately be determined by final
judicial decision from which there is no further right to appeal that such director or officer is
not entitled to be indemnified for such expenses incurred.
We have also entered into an indemnification agreement with each of our directors and certain
of our executive officers providing for indemnification to the fullest extent permitted by the
DGCL.
Section 102(b)(7) of the DGCL permits a corporation to include in its certificate of
incorporation a provision to the effect that a director of the corporation shall not be personally
liable to the corporation or its stockholders for monetary damages for breach of fiduciary duties
as a director, except for liability for any (i) breach of a director's duty of loyalty to the
corporation or its stockholders, (ii) act or omission not in good faith or that involves
intentional misconduct or a knowing violation of law, (iii) unlawful payment of dividends or
redemption of shares, or (iv) transaction from which the director derives an improper personal
benefit. Our amended and restated certificate of incorporation includes such a provision.
Our amended and restated bylaws provide that we may maintain insurance, at our expense, to
protect us and any director, officer, employee or agent of TranS1 or another corporation,
partnership, joint venture, trust or other enterprise against any expense, liability or loss,
whether or not we would have the power to indemnify such person against such expense, liability or
loss under the DGCL. We have an insurance policy covering our directors and officers
5
Table of Contents
with respect
to certain liabilities, including liabilities arising under the Securities Act, which might be
incurred by them
in such capacities and against which they cannot be indemnified by us.
The indemnification provisions set forth above and the indemnification agreements entered into
between us and our directors and certain of our officers may be sufficiently broad to permit
indemnification of our directors and officers for liabilities (including reimbursement of expenses
incurred) arising under the Securities Act. The foregoing statements are subject to the detailed
provisions of the DGCL and to the applicable provisions of our amended and restated certificate of
incorporation and amended and restated bylaws.
At present, there is no pending litigation or proceeding involving any of our directors or
executive officers as to which indemnification is required or permitted, and we are not aware of
any threatened litigation or proceeding that may result in a claim for indemnification.
Item 7.
Exemption from Registration Claimed
.
Not applicable.
Item 8.
Exhibits.
See Exhibit Index below.
Item 9. Undertakings
.
(a) We hereby undertake:
1. To file, during any period in which offers or sales are being made, a post-effective
amendment to this registration statement:
i. To include any prospectus required by section 10(a)(3) of the Securities Act of 1933;
ii. To reflect in the prospectus any facts or events arising after the effective date of the
registration statement (or the most recent post-effective amendment thereof) which, individually or
in the aggregate, represent a fundamental change in the information set forth in the registration
statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered
(if the total dollar value of securities offered would not exceed that which was registered) and
any deviation from the low or high end of the estimated maximum offering range may be reflected in
the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the
changes in volume and price represent no more than a 20% change in the maximum aggregate offering
price set forth in the "Calculation of Registration Fee" table in the effective registration
statement.
iii. To include any material information with respect to the plan of distribution not
previously disclosed in the registration statement or any material change to such information in
the registration statement;
Provided, however
, that paragraphs (a)(1)(i) and (a)(1)(ii) above do not apply if the information
required to be included in a post-effective amendment by those paragraphs is contained in periodic
reports filed with or furnished to the Commission by us pursuant to Section 13 or 15(d) of the
Exchange Act that are incorporated by reference in this registration statement.
2. That, for the purpose of determining any liability under the Securities Act of 1933, each
such post-effective amendment shall be deemed to be a new registration statement relating to the
securities offered therein, and the offering of such securities at that time shall be deemed to be
the initial bona fide offering thereof.
3. To remove from registration by means of a post-effective amendment any of the securities
being registered which remain unsold at the termination of the offering.
6
Table of Contents
(b) We hereby undertake that, for purposes of determining any liability under the Securities
Act, each filing of our annual report pursuant to Section 13(a) or Section 15(d) of the Exchange
Act that is incorporated by reference in the registration statement shall be deemed to be a new
registration statement relating to the securities offered therein, and the offering of such
securities at that time shall be deemed to be the initial bona fide offering thereof.
(c) Insofar as indemnification for liabilities arising under the Securities Act may be
permitted to directors, officers and controlling persons of the registrant pursuant to the
foregoing provisions, or otherwise, the registrant has been advised that in the opinion of the
Securities and Exchange Commission such indemnification is against public policy as expressed in
the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification
against such liabilities (other than the payment by the registrant of expenses incurred or paid by
a director, officer or controlling person of the registrant in the successful defense of any
action, suit or proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the registrant will, unless in the opinion of its
counsel the matter has been settled by controlling precedent, submit to a court of appropriate
jurisdiction the question whether such indemnification by it is against public policy as expressed
in the Securities Act and will be governed by the final adjudication of such issue.
7
Table of Contents
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, as amended, TranS1 Inc., the
registrant, certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form S-8 and has duly caused this registration statement to be signed on
its behalf by the undersigned, thereunto duly authorized, in the City of Wilmington, State of North
Carolina, on the 6th day of August, 2009.
TRANS1 INC.
By:
/s/ Richard Randall
Richard Randall
President and Chief Executive Officer
POWER OF ATTORNEY
We, the undersigned directors and officers of TranS1 Inc., do hereby constitute and appoint
Richard Randall and Michael Luetkemeyer or either of them, our true and lawful attorneys and
agents, to do any and all acts and things in our name and behalf in our capacities as directors and
officers and to execute any and all instruments for us and in our names in the capacities indicated
below, which said attorneys and agents, or either of them, may deem necessary or advisable to
enable said corporation to comply with the Securities Act of 1933, as amended, and any rules,
regulations, and requirements of the Securities and Exchange Commission, in connection with this
registration statement, including specifically, but without limitation, power and authority to sign
for us or any of us in our names and in the capacities indicated below, any and all amendments
(including post-effective amendments) to this registration statement and we do hereby ratify and
confirm all that the said attorneys and agents, or either of them, shall do or cause to be done by
virtue hereof.
Pursuant to the requirements of the Securities Act of 1933, as amended, this registration
statement has been signed below by the following persons in the capacities and on the dates
indicated.
Signature
Title
Date
/s/ Richard Randall
Richard Randall
President, Chief Executive
Officer and Director
(Principal Executive Officer)
August 6, 2009
/s/ Michael Luetkemeyer
Michael Luetkemeyer
Chief Financial Officer
(Principal Financial and
Accounting Officer)
August 6, 2009
/s/ Michael Carusi
Michael Carusi
Director
August 6, 2009
/s/ Mitchell Dann
Mitchell Dann
Director
August 6, 2009
/s/ Paul LaViolette
Paul LaViolette
Director
August 6, 2009
/s/ Jonathan Osgood
Jonathan Osgood
Director
August 6, 2009
James Shapiro
Director
/s/ Joseph Slattery
Joseph Slattery
Director
August 6, 2009
8
Table of Contents
EXHIBIT INDEX
Number
Description
4.1
Specimen Common Stock certificate (incorporated by
reference to Exhibit 4.1 to the Registration Statement on
Form S-1, as amended (File No. 333-144802), and as declared
effective on October 16, 2007).
4.2
Amended and Restated Certificate of Incorporation
of TranS1 Inc. (incorporated by reference to Exhibit 3.2 to
the Registration Statement on Form S-1, as amended (File No.
333-144802), and as declared effective on October 16, 2007).
4.3
Amended and Restated Bylaws of TranS1 Inc.
(incorporated by reference to Exhibit 3.4 to the Registration
Statement on
Form S-1,
as amended (File No. 333-144802), and
as declared effective on October 16, 2007).
5.1
Opinion of Stradling Yocca Carlson & Rauth, a
Professional Corporation.
23.1
Consent of PricewaterhouseCoopers LLP, Independent
Registered Public Accounting Firm.
23.2
Consent of Stradling Yocca Carlson & Rauth, a
Professional Corporation (included in Exhibit 5.1 hereto).
24.1
Power of Attorney (included on signature page to the
Registration Statement).
99.1
TranS1 Inc. 2007 Stock Incentive Plan, as amended
(incorporated by reference to Appendix A to the Definitive
Proxy Statement on Schedule 14A, as filed with the Commission
on April 30, 2009).