As filed with the Securities and Exchange Commission on June 30, 1997
                                                    Registration No. 33-______

                       SECURITIES AND EXCHANGE COMMISSION
                              Washington, DC 20549
                                -----------------
                                    FORM S-8
                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933
                                -----------------
                              SYMBOLLON CORPORATION
             (Exact name of registrant as specified in its charter)
                                -----------------

                  Delaware                                36-3463683
         (State or other jurisdiction of               (I.R.S. Employer
         incorporation or organization)               Identification No.)
                                -----------------

                              122 Boston Post Road
                                Sudbury, MA 01776
               (Address of principal executive offices) (Zip code)
                                -----------------

                              SYMBOLLON CORPORATION
                             1993 STOCK OPTION PLAN
                            (Full title of the plan)
                                ----------------
                                Paul C. Desjourdy
              Executive Vice President and Chief Financial Officer
                              Symbollon Corporation
                              122 Boston Post Road
                                Sudbury, MA 01776
                     (Name and address of agent for service)
                                 (508) 443-0165
          (Telephone number, including area code, of agent for service)
                                -----------------

                                    Copy to:
                            Irwin M. Rosenthal, Esq.
                      Rubin Baum Levin Constant & Friedman
                              30 Rockefeller Plaza
                               New York, NY 10112
                                 (212) 698-7700
                                -----------------

<TABLE>
<CAPTION>
                         CALCULATION OF REGISTRATION FEE
------------------------------------------------------------------------------------------------------------------------------------
                                                                    PROPOSED                PROPOSED
   TITLE OF EACH                                                     MAXIMUM                 MAXIMUM
CLASS OF SECURITIES                      AMOUNT TO BE            OFFERING PRICE             AGGREGATE                AMOUNT OF
  TO BE REGISTERED                       REGISTERED(1)            PER SHARE(2)           OFFERING PRICE(2)       REGISTRATION FEE
------------------------------------------------------------------------------------------------------------------------------------
 <S>                                       <C>                      <C>                     <C>                       <C>
 Class A Common Stock,
 (par value $.001 per share).              400,000(3)               $   1.66                $ 664,000                 $ 201.21
====================================================================================================================================
</TABLE>

(1)  Pursuant  to  Rule  416,  this  Registration  Statement  also  covers  such
indeterminable  number of additional  shares as may become issuable  pursuant to
terms designed to prevent dilution resulting from stock splits,  stock dividends
or similar  events.  (2) The price of $1.66 per share,  which was the average of
the high and low sales price of the Class A Common Stock on the NASDAQ  SmallCap
Market on June 26, 1997, is set forth solely for the purpose of calculating  the
registration  fee pursuant to Rule 457(h) under the  Securities  Act of 1933, as
amended (the "Securities  Act").  (3) Represents  shares of Class A Common Stock
reserved  for  issuance  pursuant  to  options  available  for  grant  under the
registrant's  1993 Stock Option Plan, as amended (the "Option Plan"). Of a total
of 800,000  shares of Class A Common Stock  authorized  for  issuance  under the
Option Plan, 400,000 shares were previously registered.


<PAGE>

            INCORPORATION OF CONTENTS OF PRIOR REGISTRATION STATEMENT

         The contents of the Registrant's registration statement on Form S-8, 
Registration No. 33-80368, are incorporated herein by reference.

               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

ITEM 5.  INTERESTS OF NAMED EXPERTS AND COUNSEL.

         Certain legal matters in connection with the issuance of the securities
offered  hereby will be passed upon for the Company by Rubin Baum Levin Constant
& Friedman,  New York,  New York.  Irwin M.  Rosenthal,  a partner of Rubin Baum
Levin Constant & Friedman,  may be deemed to beneficially  own 279,892 shares of
Common Stock of the Company,  of which 277,372  shares of Common Stock are owned
of record by Magar, Inc., a privately held corporation of which Mr. Rosenthal is
a director, officer and a principal stockholder.

ITEM 8.  EXHIBITS.

         The  following is a complete  list of exhibits  filed as a part of this
Registration Statement:

    Exhibit No.       Document
    -----------       --------
    5.1               Opinion of Rubin Baum Levin Constant & Friedman regarding 
                      legality.

    23.1              Consent of Rubin Baum Levin Constant & Friedman (included 
                      in Exhibit 5.1).

    23.2              Consent of Richard A. Eisner & Company, LLP.

    24.1              Power of Attorney (included on signature page hereto).



<PAGE>


                                   SIGNATURES

         Pursuant  to the  requirements  of the  Securities  Act  of  1933,  the
Registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-8 and has duly caused this Registration
Statement  to be  signed  on its  behalf  by  the  undersigned,  thereunto  duly
authorized, in the City of Sudbury,  Commonwealth of Massachusetts,  on June 30,
1997.

                                          SYMBOLLON CORPORATION
                                          (Registrant)

                                          By:   /s/ PAUL C. DESJOURDY
                                             ------------------------
                                          Paul C. Desjourdy, Executive Vice
                                          President and Chief Financial Officer

                                POWER OF ATTORNEY

         KNOW  ALL MEN BY THESE  PRESENTS,  that  each  person  whose  signature
appears below hereby  severally  constitutes  and appoints Paul C. Desjourdy and
Jack H.  Kessler  and each of them,  his true and lawful  attorneys-in-fact  and
agents,  each acting alone, with full power of substitution and  resubstitution,
for him and in his name, place and stead, in any and all capacities, to sign any
and all amendments  (including  post-effective  amendments) to this Registration
Statement on Form S-8 and all documents relating thereto,  and to file the same,
with all exhibits thereto, and other documents in connection therewith, with the
Securities and Exchange Commission, and to make any and all state securities law
or blue sky  filings,  granting  unto said  attorneys-in-fact  and agents,  each
acting  alone full power and  authority to do and perform each and every act and
thing  necessary or advisable to be done in and about the premises,  as fully to
all intents and purposes as he might or could do in person, hereby ratifying and
confirming  all that said  attorneys-in-fact  and agents,  or his  substitute or
substitutes, may lawfully do or cause to be done by virtue hereof.

         Pursuant  to the  requirements  of the  Securities  Act of  1933,  this
registration  statement,  or  amendment  thereto,  has been signed  below by the
following persons in the capacities and on the dates indicated:

         Signature                Title                                Date
         ---------                -----                                ----
/s/ Jack H. Kessler               Executive Vice-President,        June 30, 1997
---------------------------       Chief Scientific Officer,
     Jack H. Kessler              Secretary and Chairman
                                  of the Board of Directors
                                  (Principal Executive Officer)

/s/ Paul C. Desjourdy             Executive Vice President         June 30, 1997
---------------------------       Treasurer, Chief Financial
    Paul C. Desjourdy             Officer, and Director (Principal
                                  Financial and Accounting Officer)

/s/ Stuart M. Paley               Director                         June 30, 1997
---------------------------
    Stuart M. Paley

/s/ Edward A. Mason               Director                         June 30, 1997
---------------------------
    Edward A. Mason

/s/ James C. Richards             Director                         June 30, 1997
---------------------------
    James C. Richards
[{"type": "S-8", "sequence": "1", "description": "FORM S-8 - 1993 STOCK OPTION PLAN", "secsgml_size_bytes": 9395}]
{"company-data": {"conformed-name": "SYMBOLLON CORP", "cik": "0000912086", "assigned-sic": "2836", "irs-number": "363463683", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-30359", "film-number": "97632926"}, "business-address": {"street1": "122 BOSTON POST RD", "city": "SUDBURY", "state": "MA", "zip": "01776", "phone": "5084430165"}, "mail-address": {"street1": "122 BOSTON POST RD", "city": "SUDBURY", "state": "MA", "zip": "01776"}}
As filed with the Securities and Exchange Commission on June 30, 1997
                                                    Registration No. 33-______

                       SECURITIES AND EXCHANGE COMMISSION
                              Washington, DC 20549
                                -----------------
                                    FORM S-8
                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933
                                -----------------
                              SYMBOLLON CORPORATION
             (Exact name of registrant as specified in its charter)
                                -----------------

                  Delaware                                36-3463683
         (State or other jurisdiction of               (I.R.S. Employer
         incorporation or organization)               Identification No.)
                                -----------------

                              122 Boston Post Road
                                Sudbury, MA 01776
               (Address of principal executive offices) (Zip code)
                                -----------------

                              SYMBOLLON CORPORATION
                             1993 STOCK OPTION PLAN
                            (Full title of the plan)
                                ----------------
                                Paul C. Desjourdy
              Executive Vice President and Chief Financial Officer
                              Symbollon Corporation
                              122 Boston Post Road
                                Sudbury, MA 01776
                     (Name and address of agent for service)
                                 (508) 443-0165
          (Telephone number, including area code, of agent for service)
                                -----------------

                                    Copy to:
                            Irwin M. Rosenthal, Esq.
                      Rubin Baum Levin Constant & Friedman
                              30 Rockefeller Plaza
                               New York, NY 10112
                                 (212) 698-7700
                                -----------------
CALCULATION OF REGISTRATION FEE
------------------------------------------------------------------------------------------------------------------------------------
                                                                    PROPOSED                PROPOSED
   TITLE OF EACH                                                     MAXIMUM                 MAXIMUM
CLASS OF SECURITIES                      AMOUNT TO BE            OFFERING PRICE             AGGREGATE                AMOUNT OF
  TO BE REGISTERED                       REGISTERED(1)            PER SHARE(2)           OFFERING PRICE(2)       REGISTRATION FEE
------------------------------------------------------------------------------------------------------------------------------------
Class A Common Stock,
 (par value $.001 per share).              400,000(3)               $   1.66                $ 664,000                 $ 201.21
====================================================================================================================================
(1)  Pursuant  to  Rule  416,  this  Registration  Statement  also  covers  such
indeterminable  number of additional  shares as may become issuable  pursuant to
terms designed to prevent dilution resulting from stock splits,  stock dividends
or similar  events.  (2) The price of $1.66 per share,  which was the average of
the high and low sales price of the Class A Common Stock on the NASDAQ  SmallCap
Market on June 26, 1997, is set forth solely for the purpose of calculating  the
registration  fee pursuant to Rule 457(h) under the  Securities  Act of 1933, as
amended (the "Securities  Act").  (3) Represents  shares of Class A Common Stock
reserved  for  issuance  pursuant  to  options  available  for  grant  under the
registrant's  1993 Stock Option Plan, as amended (the "Option Plan"). Of a total
of 800,000  shares of Class A Common Stock  authorized  for  issuance  under the
Option Plan, 400,000 shares were previously registered.
INCORPORATION OF CONTENTS OF PRIOR REGISTRATION STATEMENT

         The contents of the Registrant's registration statement on Form S-8, 
Registration No. 33-80368, are incorporated herein by reference.

               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

ITEM 5.  INTERESTS OF NAMED EXPERTS AND COUNSEL.

         Certain legal matters in connection with the issuance of the securities
offered  hereby will be passed upon for the Company by Rubin Baum Levin Constant
& Friedman,  New York,  New York.  Irwin M.  Rosenthal,  a partner of Rubin Baum
Levin Constant & Friedman,  may be deemed to beneficially  own 279,892 shares of
Common Stock of the Company,  of which 277,372  shares of Common Stock are owned
of record by Magar, Inc., a privately held corporation of which Mr. Rosenthal is
a director, officer and a principal stockholder.

ITEM 8.  EXHIBITS.

         The  following is a complete  list of exhibits  filed as a part of this
Registration Statement:

    Exhibit No.       Document
    -----------       --------
    5.1               Opinion of Rubin Baum Levin Constant & Friedman regarding 
                      legality.

    23.1              Consent of Rubin Baum Levin Constant & Friedman (included 
                      in Exhibit 5.1).

    23.2              Consent of Richard A. Eisner & Company, LLP.

    24.1              Power of Attorney (included on signature page hereto).
SIGNATURES

         Pursuant  to the  requirements  of the  Securities  Act  of  1933,  the
Registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-8 and has duly caused this Registration
Statement  to be  signed  on its  behalf  by  the  undersigned,  thereunto  duly
authorized, in the City of Sudbury,  Commonwealth of Massachusetts,  on June 30,
1997.

                                          SYMBOLLON CORPORATION
                                          (Registrant)

                                          By:   /s/ PAUL C. DESJOURDY
                                             ------------------------
                                          Paul C. Desjourdy, Executive Vice
                                          President and Chief Financial Officer

                                POWER OF ATTORNEY

         KNOW  ALL MEN BY THESE  PRESENTS,  that  each  person  whose  signature
appears below hereby  severally  constitutes  and appoints Paul C. Desjourdy and
Jack H.  Kessler  and each of them,  his true and lawful  attorneys-in-fact  and
agents,  each acting alone, with full power of substitution and  resubstitution,
for him and in his name, place and stead, in any and all capacities, to sign any
and all amendments  (including  post-effective  amendments) to this Registration
Statement on Form S-8 and all documents relating thereto,  and to file the same,
with all exhibits thereto, and other documents in connection therewith, with the
Securities and Exchange Commission, and to make any and all state securities law
or blue sky  filings,  granting  unto said  attorneys-in-fact  and agents,  each
acting  alone full power and  authority to do and perform each and every act and
thing  necessary or advisable to be done in and about the premises,  as fully to
all intents and purposes as he might or could do in person, hereby ratifying and
confirming  all that said  attorneys-in-fact  and agents,  or his  substitute or
substitutes, may lawfully do or cause to be done by virtue hereof.

         Pursuant  to the  requirements  of the  Securities  Act of  1933,  this
registration  statement,  or  amendment  thereto,  has been signed  below by the
following persons in the capacities and on the dates indicated:

         Signature                Title                                Date
         ---------                -----                                ----
/s/ Jack H. Kessler               Executive Vice-President,        June 30, 1997
---------------------------       Chief Scientific Officer,
     Jack H. Kessler              Secretary and Chairman
                                  of the Board of Directors
                                  (Principal Executive Officer)

/s/ Paul C. Desjourdy             Executive Vice President         June 30, 1997
---------------------------       Treasurer, Chief Financial
    Paul C. Desjourdy             Officer, and Director (Principal
                                  Financial and Accounting Officer)

/s/ Stuart M. Paley               Director                         June 30, 1997
---------------------------
    Stuart M. Paley

/s/ Edward A. Mason               Director                         June 30, 1997
---------------------------
    Edward A. Mason

/s/ James C. Richards             Director                         June 30, 1997
---------------------------
    James C. Richards