<PAGE>

       As filed with the Securities and Exchange Commission on May 3, 1995
                                                       REGISTRATION NO. 33-
- -------------------------------------------------------------------------------
- -------------------------------------------------------------------------------
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                               -------------------

                                    FORM S-8
                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933

                               -------------------

                               IMMUNEX CORPORATION
             (Exact name of Registrant as specified in its charter)


           Washington                                  51-0346580
(State or other jurisdiction of             (I.R.S. Employer Identification No.)
 incorporation or organization)

                              51 University Street
                           Seattle, Washington  98101
               (Address of Principal Executive Offices)(Zip Code)

                               IMMUNEX CORPORATION
                   AMENDED AND RESTATED 1993 STOCK OPTION PLAN
                            (Full title of the plan)

                               SCOTT G. HALLQUIST
                    Senior Vice President and General Counsel
                               IMMUNEX CORPORATION
                              51 University Street
                           Seattle, Washington  98101
                                 (206) 587-0430
            (Name, address and telephone number of agent for service)

                               -------------------

                                    Copy to:

                                STEPHEN M. GRAHAM
                                  PERKINS COIE
                          1201 Third Avenue, 40th Floor
                         Seattle, Washington  98101-3099

                               -------------------

                         CALCULATION OF REGISTRATION FEE

<TABLE>
<S>                                   <C>             <C>                            <C>                            <C>
- ------------------------------------------------------------------------------------------------------------------------------------
- ------------------------------------------------------------------------------------------------------------------------------------
       Title of Securities            Number to Be         Proposed Maximum               Proposed Maximum              Amount of
         to Be Registered              Registered     Offering Price Per Share(1)    Aggregate Offering Price(1)    Registration Fee
- ------------------------------------------------------------------------------------------------------------------------------------
 Common Stock, par value
   $.01 per share. . . . . . . . .    5,000,000(2)              $11.875                       $59,375,000                 $20,474
- ------------------------------------------------------------------------------------------------------------------------------------
- ------------------------------------------------------------------------------------------------------------------------------------

<FN>
(1)  Estimated pursuant to Rule 457(c) solely for the purpose of calculating the
     amount of the registration fee.  The price per share is estimated to be
     $11.875 based on the average of the high and low price for the Common Stock
     in the over-the-counter market on April 28, 1995, as reported by the Nasdaq
     National Market.

(2)  Together with an indeterminate number of additional shares which may be
     necessary to adjust the number of shares reserved for issuance pursuant to
     the Immunex Corporation Amended and Restated 1993 Stock Option Plan as the
     result of any future stock split, stock dividend or similar adjustment of
     the outstanding Common Stock of the Company.

</TABLE>


<PAGE>

                                     PART II

                 INFORMATION REQUIRED IN REGISTRATION STATEMENT

ITEM 3.  INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

         The following documents are hereby incorporated by reference in this
Registration Statement:

               (a)  The Registrant's Annual Report on Form 10-K for the year
ended December 31, 1994, which contains audited financial statements for the
most recent year for which such statements have been filed;

               (b)  All other reports filed by the Registrant pursuant to
Section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended (the
"Exchange Act"), since the end of the fiscal year covered by the Annual Report
referred to in (a) above; and

               (c)  The description of the Registrant's Common Stock contained
in the Registration Statement on Form 8-A filed with the Commission on May 12,
1983, under Section 12 of the Exchange Act, including any amendments or reports
filed for the purpose of updating such description.

         All documents filed by the Registrant pursuant to Sections 13(a),
13(c), 14 and 15(d) of the Exchange Act, after the date hereof and prior to the
filing of a post-effective amendment which indicates that all securities offered
hereby have been sold or which deregisters all securities covered hereby then
remaining unsold, shall also be deemed to be incorporated by reference into this
Registration Statement and to be a part hereof commencing on the respective
dates on which such documents are filed.


ITEM 6.  INDEMNIFICATION OF DIRECTORS AND OFFICERS

         Sections 23B.08.500 through 23B.08.600 of the Washington Business
Corporation Act (the "WBCA") authorize a court to award, or a corporation's
board of directors to grant, indemnification to directors and officers on terms
sufficiently broad to permit indemnification under certain circumstances for
liabilities arising under the Securities Act of 1933, as amended (the
"Securities Act").  Under the WBCA, a corporation has the power to indemnify a
director or officer made a party to a proceeding, or advance or reimburse
expenses incurred in a proceeding, under any circumstances, except that no such
indemnification shall be allowed on account of:  (i) acts or omissions of a
director or officer finally adjudged to be intentional misconduct or a knowing
violation of the law; (ii) conduct of a director or officer finally adjudged to
be an unlawful distribution; or (iii) any transaction with respect to which it
was finally adjudged that such director or officer personally received a benefit
in money, property or services to which the director or officer was not legally
entitled.  Article XII of Immunex Corporation's Articles of Incorporation
provide for indemnification of Immunex's directors and officers to the maximum
extent permitted by Washington law.

     Section 23B.08.320 of the WBCA authorizes a corporation to limit a
director's liability to the corporation or its shareholders for monetary damages
for acts or omissions as a director, except in certain circumstances involving
intentional misconduct, self dealing or illegal corporate loans or
distributions, or any transaction from which the director personally receives a
benefit in money, property or services to which the director is not legally
entitled.  Article XI of Immunex Corporation's Articles of Incorporation
contains provisions implementing, to the fullest extent permitted by Washington
law, such limitations on a director's liability to Immunex and its shareholders.
Any amendment or repeal of such Article XI may not adversely affect any right or
protection of a director of Immunex for or with respect to any acts or omissions
of such director occurring prior to such amendment or repeal.  The affirmative
vote of 80% of the voting stock of Immunex is required to amend, or to adopt any
provision inconsistent with, such Article XI.



                                      II-1
<PAGE>

     IMMUNEX HAS ENTERED INTO SEPARATE INDEMNIFICATION AGREEMENTS WITH EACH OF
ITS DIRECTORS AND OFFICERS CONTAINING PROVISIONS THAT ARE IN SOME RESPECTS
BROADER THAN THE SPECIFIC INDEMNIFICATION PROVISIONS CONTAINED IN THE WBCA.
THESE AGREEMENTS REQUIRE IMMUNEX, AMONG OTHER THINGS, TO INDEMNIFY SUCH
DIRECTORS AND OFFICERS AGAINST CERTAIN LIABILITIES THAT MAY ARISE BY REASON OF
THEIR STATUS OR SERVICE AS DIRECTORS OR OFFICERS, AND TO ADVANCE THEIR EXPENSES
INCURRED AS A RESULT OF ANY PROCEEDING AGAINST THEM AS TO WHICH THEY COULD BE
INDEMNIFIED.

     Directors and officers of Immunex are covered by insurance (with certain
exceptions and limitations) which indemnifies them against losses and
liabilities arising from certain alleged "wrongful acts," including alleged
errors or misstatements or misleading statements, or certain other alleged
wrongful acts or omission constituting neglect or breach of duty.


ITEM 8.  EXHIBITS

   Exhibit
   Number                               Description
- ------------- -----------------------------------------------------------------

     4.1      Immunex Corporation Amended and Restated 1993 Stock Option Plan

     5.1      Opinion of Perkins Coie regarding legality of the Common Stock
              being registered

    23.1      Consent of Ernst & Young LLP

    23.2      Consent of Perkins Coie (included in opinion filed as Exhibit 5.1)

    24.1      Powers of Attorney (see Signature Page)


ITEM 9.  UNDERTAKINGS

A.   The undersigned Registrant hereby undertakes:

     (1)    To file, during any period in which offers or sales are being made,
a post-effective amendment to this Registration Statement:

            (i)    To include any prospectus required by Section 10(a)(3) of the
Securities Act;

            (ii)   To reflect in the prospectus any facts or events arising
after the effective date of this Registration Statement (or the most recent
post-effective amendment thereof) which, individually or in the aggregate,
represent a fundamental change in the information set forth in this Registration
Statement; and

            (iii)  To include any material information with respect to the plan
of distribution not previously disclosed in this Registration Statement or any
material change to such information in this Registration Statement;

PROVIDED, HOWEVER, that paragraphs (1)(i) and (1)(ii) above do not apply if the
information required to be included in a post-effective amendment by those
paragraphs is contained in periodic reports filed by the Registrant pursuant to
Section 13 or Section 15(d) of the Exchange Act that are incorporated by
reference in this Registration Statement.


                                    II-2


<PAGE>

     (2)    That, for the purpose of determining any liability under the
Securities Act, each such post-effective amendment shall be deemed to be a new
registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.

     (3)    To remove from registration by means of a post-effective amendment
any of the securities being registered which remain unsold at the termination of
the offering.

B.   The undersigned Registrant hereby undertakes that, for purposes of
determining any liability under the Securities Act, each filing of the
Registrant's annual report pursuant to Section 13(a) or 15(d) of the Exchange
Act (and, where applicable, each filing of an employee benefits plan's annual
report pursuant to Section 15(d) of the Exchange Act) that is incorporated by
reference in this Registration Statement shall be deemed to be a new
registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.

C.   Insofar as indemnification for liabilities arising under the Securities Act
may be permitted to directors, officers and controlling persons of the
Registrant pursuant to the foregoing provisions, or otherwise, the Registrant
has been advised that in the opinion of the Securities and Exchange Commission
such indemnification is against public policy as expressed in the Securities Act
and is, therefore, unenforceable.  In the event that a claim for indemnification
against such liabilities (other than the payment by the Registrant of expenses
incurred or paid by a director, officer or controlling person of the Registrant
in the successful defense of any action, suit or proceeding) is asserted by such
director, officer or controlling person in connection with the securities being
registered, the Registrant will, unless in the opinion of its counsel the matter
has been settled by controlling precedent, submit to a court of appropriate
jurisdiction the question whether such indemnification by it is against public
policy as expressed in the Securities Act and will be governed by the final
adjudication of such issue.



                                      II-3


<PAGE>

                                   SIGNATURES

     Pursuant to the requirements of the Securities Act of 1933, as amended, the
Registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of Seattle, State of Washington, on the 26th day of
April, 1995.

                                   IMMUNEX CORPORATION


                                   By      SCOTT G. HALLQUIST
                                       -----------------------------------------
                                       Scott G. Hallquist, Senior Vice President



                                POWER OF ATTORNEY

     Each person whose signature appears below constitutes and appoints
Douglas G. Southern and Scott G. Hallquist, or either of them, his or her
attorneys-in-fact, with the power of substitution, for him or her in any and all
capacities, to sign any amendments to this Registration Statement, and to file
the same, with exhibits thereto and other documents in connection therewith,
with the Securities and Exchange Commission, hereby ratifying and confirming all
that said attorneys-in-fact, or their substitute or substitutes, may do or cause
to be done by virtue hereof.

     Pursuant to the requirements of the Securities Act of 1933, as amended,
this Registration Statement has been signed below by the following persons on
the 26th day of April, 1995 in the capacities indicated.

<TABLE>
<CAPTION>

                 SIGNATURE                                    TITLE
<S>                                               <C>
   EDWARD V. FRITZKY                             Chairman and Chief Executive Officer (Principal
- ------------------------------------------        Executive Officer)
            Edward V. Fritzky

   DOUGLAS G. SOUTHERN                           Senior Vice President and Chief Financial Officer
- ------------------------------------------        (Principal Financial and Accounting Officer)
           Douglas G. Southern

   JOSEPH J. CARR                                Director
- ------------------------------------------
             Joseph J. Carr

   KIRBY L. CRAMER, SR.                          Director
- ------------------------------------------
          Kirby L. Cramer, Sr.

                                                  Director
- ------------------------------------------
            Robert A. Essner

   STEVEN GILLIS                                 Director
- ------------------------------------------
              Steven Gillis

   MICHAEL L. KRANDA                             Director
- ------------------------------------------
            Michael L. Kranda

   JOHN E. LYONS                                 Director
- ------------------------------------------
               John E. Lyons

    EDITH W. MARTIN                              Director
- ------------------------------------------
              Edith W. Martin

</TABLE>

                                        II-4



<PAGE>

                         CONSENT OF INDEPENDENT AUDITORS

     We consent to the incorporation by reference in the Registration Statement
on Form S-8 pertaining to the Immunex Corporation Amended and Restated 1993
Stock Option Plan of our report dated January 20, 1995, with respect to the
consolidated financial statements and schedule of Immunex Corporation included
in its Annual Report (Form 10-K) for the year ended December 31, 1994, filed
with the Securities and Exchange Commission.

                                        ERNST & YOUNG LLP


Seattle, Washington
May 1, 1995


                                    II-5


<PAGE>

                                INDEX TO EXHIBITS

<TABLE>
<CAPTION>

     Exhibit
     Number                                  Description
 -------------- ----------------------------------------------------------------
<S>             <C>
       4.1      Immunex Corporation Amended and Restated 1993 Stock Option Plan

       5.1      Opinion of Perkins Coie regarding legality of the Common Stock
                being registered . . . . . . . . . . . . . . . . . . . . . . . .

      23.1      Consent of Ernst & Young LLP (see Page II-5) . . . . . . . . . .

      23.2      Consent of Perkins Coie (included in Exhibit 5.1). . . . . . . .

      24.1      Power of Attorney (see Signature Page) . . . . . . . . . . . . .

</TABLE>
[{"type": "S-8", "sequence": "1", "description": "S-8", "secsgml_size_bytes": 17689}]
{"company-data": {"conformed-name": "IMMUNEX CORP /DE/", "cik": "0000719529", "assigned-sic": "2836", "irs-number": "510346580", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "033-59061", "film-number": "95534299"}, "business-address": {"street1": "51 UNIVERSITY ST", "city": "SEATTLE", "state": "WA", "zip": "98101", "phone": "2065870430"}, "mail-address": {"street1": "51 UNIVERSITY STREET", "city": "SEATLE", "state": "WA", "zip": "98101"}}
As filed with the Securities and Exchange Commission on May 3, 1995
                                                       REGISTRATION NO. 33-
- -------------------------------------------------------------------------------
- -------------------------------------------------------------------------------
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                               -------------------

                                    FORM S-8
                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933

                               -------------------

                               IMMUNEX CORPORATION
             (Exact name of Registrant as specified in its charter)

           Washington                                  51-0346580
(State or other jurisdiction of             (I.R.S. Employer Identification No.)
 incorporation or organization)

                              51 University Street
                           Seattle, Washington  98101
               (Address of Principal Executive Offices)(Zip Code)

                               IMMUNEX CORPORATION
                   AMENDED AND RESTATED 1993 STOCK OPTION PLAN
                            (Full title of the plan)

                               SCOTT G. HALLQUIST
                    Senior Vice President and General Counsel
                               IMMUNEX CORPORATION
                              51 University Street
                           Seattle, Washington  98101
                                 (206) 587-0430
            (Name, address and telephone number of agent for service)

                               -------------------

                                    Copy to:

                                STEPHEN M. GRAHAM
                                  PERKINS COIE
                          1201 Third Avenue, 40th Floor
                         Seattle, Washington  98101-3099

                               -------------------

                         CALCULATION OF REGISTRATION FEE
- ------------------------------------------------------------------------------------------------------------------------------------
- ------------------------------------------------------------------------------------------------------------------------------------
       Title of Securities            Number to Be         Proposed Maximum               Proposed Maximum              Amount of
         to Be Registered              Registered     Offering Price Per Share(1)    Aggregate Offering Price(1)    Registration Fee
- ------------------------------------------------------------------------------------------------------------------------------------
 Common Stock, par value
   $.01 per share. . . . . . . . .    5,000,000(2)              $11.875                       $59,375,000                 $20,474
- ------------------------------------------------------------------------------------------------------------------------------------
- ------------------------------------------------------------------------------------------------------------------------------------
(1)  Estimated pursuant to Rule 457(c) solely for the purpose of calculating the
     amount of the registration fee.  The price per share is estimated to be
     $11.875 based on the average of the high and low price for the Common Stock
     in the over-the-counter market on April 28, 1995, as reported by the Nasdaq
     National Market.

(2)  Together with an indeterminate number of additional shares which may be
     necessary to adjust the number of shares reserved for issuance pursuant to
     the Immunex Corporation Amended and Restated 1993 Stock Option Plan as the
     result of any future stock split, stock dividend or similar adjustment of
     the outstanding Common Stock of the Company.
PART II

                 INFORMATION REQUIRED IN REGISTRATION STATEMENT

ITEM 3.  INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

         The following documents are hereby incorporated by reference in this
Registration Statement:

               (a)  The Registrant's Annual Report on Form 10-K for the year
ended December 31, 1994, which contains audited financial statements for the
most recent year for which such statements have been filed;

               (b)  All other reports filed by the Registrant pursuant to
Section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended (the
"Exchange Act"), since the end of the fiscal year covered by the Annual Report
referred to in (a) above; and

               (c)  The description of the Registrant's Common Stock contained
in the Registration Statement on Form 8-A filed with the Commission on May 12,
1983, under Section 12 of the Exchange Act, including any amendments or reports
filed for the purpose of updating such description.

         All documents filed by the Registrant pursuant to Sections 13(a),
13(c), 14 and 15(d) of the Exchange Act, after the date hereof and prior to the
filing of a post-effective amendment which indicates that all securities offered
hereby have been sold or which deregisters all securities covered hereby then
remaining unsold, shall also be deemed to be incorporated by reference into this
Registration Statement and to be a part hereof commencing on the respective
dates on which such documents are filed.

ITEM 6.  INDEMNIFICATION OF DIRECTORS AND OFFICERS

         Sections 23B.08.500 through 23B.08.600 of the Washington Business
Corporation Act (the "WBCA") authorize a court to award, or a corporation's
board of directors to grant, indemnification to directors and officers on terms
sufficiently broad to permit indemnification under certain circumstances for
liabilities arising under the Securities Act of 1933, as amended (the
"Securities Act").  Under the WBCA, a corporation has the power to indemnify a
director or officer made a party to a proceeding, or advance or reimburse
expenses incurred in a proceeding, under any circumstances, except that no such
indemnification shall be allowed on account of:  (i) acts or omissions of a
director or officer finally adjudged to be intentional misconduct or a knowing
violation of the law; (ii) conduct of a director or officer finally adjudged to
be an unlawful distribution; or (iii) any transaction with respect to which it
was finally adjudged that such director or officer personally received a benefit
in money, property or services to which the director or officer was not legally
entitled.  Article XII of Immunex Corporation's Articles of Incorporation
provide for indemnification of Immunex's directors and officers to the maximum
extent permitted by Washington law.

     Section 23B.08.320 of the WBCA authorizes a corporation to limit a
director's liability to the corporation or its shareholders for monetary damages
for acts or omissions as a director, except in certain circumstances involving
intentional misconduct, self dealing or illegal corporate loans or
distributions, or any transaction from which the director personally receives a
benefit in money, property or services to which the director is not legally
entitled.  Article XI of Immunex Corporation's Articles of Incorporation
contains provisions implementing, to the fullest extent permitted by Washington
law, such limitations on a director's liability to Immunex and its shareholders.
Any amendment or repeal of such Article XI may not adversely affect any right or
protection of a director of Immunex for or with respect to any acts or omissions
of such director occurring prior to such amendment or repeal.  The affirmative
vote of 80% of the voting stock of Immunex is required to amend, or to adopt any
provision inconsistent with, such Article XI.

                                      II-1
IMMUNEX HAS ENTERED INTO SEPARATE INDEMNIFICATION AGREEMENTS WITH EACH OF
ITS DIRECTORS AND OFFICERS CONTAINING PROVISIONS THAT ARE IN SOME RESPECTS
BROADER THAN THE SPECIFIC INDEMNIFICATION PROVISIONS CONTAINED IN THE WBCA.
THESE AGREEMENTS REQUIRE IMMUNEX, AMONG OTHER THINGS, TO INDEMNIFY SUCH
DIRECTORS AND OFFICERS AGAINST CERTAIN LIABILITIES THAT MAY ARISE BY REASON OF
THEIR STATUS OR SERVICE AS DIRECTORS OR OFFICERS, AND TO ADVANCE THEIR EXPENSES
INCURRED AS A RESULT OF ANY PROCEEDING AGAINST THEM AS TO WHICH THEY COULD BE
INDEMNIFIED.

     Directors and officers of Immunex are covered by insurance (with certain
exceptions and limitations) which indemnifies them against losses and
liabilities arising from certain alleged "wrongful acts," including alleged
errors or misstatements or misleading statements, or certain other alleged
wrongful acts or omission constituting neglect or breach of duty.

ITEM 8.  EXHIBITS

   Exhibit
   Number                               Description
- ------------- -----------------------------------------------------------------

     4.1      Immunex Corporation Amended and Restated 1993 Stock Option Plan

     5.1      Opinion of Perkins Coie regarding legality of the Common Stock
              being registered

    23.1      Consent of Ernst & Young LLP

    23.2      Consent of Perkins Coie (included in opinion filed as Exhibit 5.1)

    24.1      Powers of Attorney (see Signature Page)

ITEM 9.  UNDERTAKINGS

A.   The undersigned Registrant hereby undertakes:

     (1)    To file, during any period in which offers or sales are being made,
a post-effective amendment to this Registration Statement:

            (i)    To include any prospectus required by Section 10(a)(3) of the
Securities Act;

            (ii)   To reflect in the prospectus any facts or events arising
after the effective date of this Registration Statement (or the most recent
post-effective amendment thereof) which, individually or in the aggregate,
represent a fundamental change in the information set forth in this Registration
Statement; and

            (iii)  To include any material information with respect to the plan
of distribution not previously disclosed in this Registration Statement or any
material change to such information in this Registration Statement;

PROVIDED, HOWEVER, that paragraphs (1)(i) and (1)(ii) above do not apply if the
information required to be included in a post-effective amendment by those
paragraphs is contained in periodic reports filed by the Registrant pursuant to
Section 13 or Section 15(d) of the Exchange Act that are incorporated by
reference in this Registration Statement.

                                    II-2
(2)    That, for the purpose of determining any liability under the
Securities Act, each such post-effective amendment shall be deemed to be a new
registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.

     (3)    To remove from registration by means of a post-effective amendment
any of the securities being registered which remain unsold at the termination of
the offering.

B.   The undersigned Registrant hereby undertakes that, for purposes of
determining any liability under the Securities Act, each filing of the
Registrant's annual report pursuant to Section 13(a) or 15(d) of the Exchange
Act (and, where applicable, each filing of an employee benefits plan's annual
report pursuant to Section 15(d) of the Exchange Act) that is incorporated by
reference in this Registration Statement shall be deemed to be a new
registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.

C.   Insofar as indemnification for liabilities arising under the Securities Act
may be permitted to directors, officers and controlling persons of the
Registrant pursuant to the foregoing provisions, or otherwise, the Registrant
has been advised that in the opinion of the Securities and Exchange Commission
such indemnification is against public policy as expressed in the Securities Act
and is, therefore, unenforceable.  In the event that a claim for indemnification
against such liabilities (other than the payment by the Registrant of expenses
incurred or paid by a director, officer or controlling person of the Registrant
in the successful defense of any action, suit or proceeding) is asserted by such
director, officer or controlling person in connection with the securities being
registered, the Registrant will, unless in the opinion of its counsel the matter
has been settled by controlling precedent, submit to a court of appropriate
jurisdiction the question whether such indemnification by it is against public
policy as expressed in the Securities Act and will be governed by the final
adjudication of such issue.

                                      II-3
SIGNATURES

     Pursuant to the requirements of the Securities Act of 1933, as amended, the
Registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of Seattle, State of Washington, on the 26th day of
April, 1995.

                                   IMMUNEX CORPORATION

                                   By      SCOTT G. HALLQUIST
                                       -----------------------------------------
                                       Scott G. Hallquist, Senior Vice President

                                POWER OF ATTORNEY

     Each person whose signature appears below constitutes and appoints
Douglas G. Southern and Scott G. Hallquist, or either of them, his or her
attorneys-in-fact, with the power of substitution, for him or her in any and all
capacities, to sign any amendments to this Registration Statement, and to file
the same, with exhibits thereto and other documents in connection therewith,
with the Securities and Exchange Commission, hereby ratifying and confirming all
that said attorneys-in-fact, or their substitute or substitutes, may do or cause
to be done by virtue hereof.

     Pursuant to the requirements of the Securities Act of 1933, as amended,
this Registration Statement has been signed below by the following persons on
the 26th day of April, 1995 in the capacities indicated.
SIGNATURE                                    TITLE
EDWARD V. FRITZKY                             Chairman and Chief Executive Officer (Principal
- ------------------------------------------        Executive Officer)
            Edward V. Fritzky

   DOUGLAS G. SOUTHERN                           Senior Vice President and Chief Financial Officer
- ------------------------------------------        (Principal Financial and Accounting Officer)
           Douglas G. Southern

   JOSEPH J. CARR                                Director
- ------------------------------------------
             Joseph J. Carr

   KIRBY L. CRAMER, SR.                          Director
- ------------------------------------------
          Kirby L. Cramer, Sr.

                                                  Director
- ------------------------------------------
            Robert A. Essner

   STEVEN GILLIS                                 Director
- ------------------------------------------
              Steven Gillis

   MICHAEL L. KRANDA                             Director
- ------------------------------------------
            Michael L. Kranda

   JOHN E. LYONS                                 Director
- ------------------------------------------
               John E. Lyons

    EDITH W. MARTIN                              Director
- ------------------------------------------
              Edith W. Martin
II-4
CONSENT OF INDEPENDENT AUDITORS

     We consent to the incorporation by reference in the Registration Statement
on Form S-8 pertaining to the Immunex Corporation Amended and Restated 1993
Stock Option Plan of our report dated January 20, 1995, with respect to the
consolidated financial statements and schedule of Immunex Corporation included
in its Annual Report (Form 10-K) for the year ended December 31, 1994, filed
with the Securities and Exchange Commission.

                                        ERNST & YOUNG LLP

Seattle, Washington
May 1, 1995

                                    II-5
INDEX TO EXHIBITS
Exhibit
     Number                                  Description
 -------------- ----------------------------------------------------------------
4.1      Immunex Corporation Amended and Restated 1993 Stock Option Plan

       5.1      Opinion of Perkins Coie regarding legality of the Common Stock
                being registered . . . . . . . . . . . . . . . . . . . . . . . .

      23.1      Consent of Ernst & Young LLP (see Page II-5) . . . . . . . . . .

      23.2      Consent of Perkins Coie (included in Exhibit 5.1). . . . . . . .

      24.1      Power of Attorney (see Signature Page) . . . . . . . . . . . . .