As filed with the Securities and Exchange Commission on December 14, 1999
                                                  Registration No. 333-_________
------------------------------------------------------------------------------

                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                                ----------------

                                    FORM S-8

             REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933

                          DENDRITE INTERNATIONAL, INC.
                          ----------------------------
             (Exact name of registrant as specified in its charter)

                                   New Jersey
                                   ----------
         (State or other jurisdiction of incorporation or organization)

                                   22-2786386
                                   ----------
                      (I.R.S. Employer Identification No.)


             1200 Mount Kemble Avenue, Morristown, New Jersey 07960-6797
             -----------------------------------------------------------
    (Address, including zip code, of registrant's principal executive offices)

                          DENDRITE INTERNATIONAL, INC.
                           DEFERRED COMPENSATION PLAN
                          ----------------------------
                            (Full title of the Plan)

                               CHRISTOPHER J. FRENCH
                 Vice President, General Counsel and Secretary
                          DENDRITE INTERNATIONAL, INC.
                            1200 Mount Kemble Avenue
                        Morristown, New Jersey 07960-6797
                        ---------------------------------
                     (Name and address of agent for service)

                                 (973) 425-1200
                                 --------------
         (Telephone number, including area code, of agent for service)

                                     -------
                                 With a copy to:
                              Warren J. Casey, Esq.
                        Pitney, Hardin, Kipp & Szuch LLP
                                  P.O. Box 1945
                          Morristown, New Jersey 07962
                                 (973) 966-8025



<PAGE>

<TABLE>
<CAPTION>
                         CALCULATION OF REGISTRATION FEE

------------------------- ---------------------- ----------------------- ---------------------- ----------------------
  Title of securities         Amount to be          Proposed Maximum       Proposed Maximum           Amount of
    to be registered           Registered            Offering Price       Aggregate Offering         Registration
                                                      Per Share(1)             Price (2)                 Fee (2)
------------------------- ---------------------- ----------------------- ---------------------- ----------------------
<S>                         <C>                        <C>                    <C>                      <C>
Deferred Compensation
   Obligations (1)          N/A                        N/A                     N/A                     $462.00
------------------------- ---------------------- ----------------------- ---------------------- ----------------------

</TABLE>

--------------------------

(1) The Deferred Compensation  Obligations are unsecured obligations of Dendrite
International, Inc. to  pay deferred  compensation  in the future in  accordance
with the terms of the Dendrite International, Inc. Deferred Compensation Plan.

(2) Based upon estimated obligations in the amount of $462.00 used solely for
the purpose of calculating the registration fee.



<PAGE>


                                     PART I
              INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS

                                EXPLANATORY NOTE

         As permitted by Rule 428 under the  Securities  Act of 1933, as amended
(the  "Securities  Act"),  this  registration  statement  omits the  information
specified  in Part I of Form  S-8.  The  documents  containing  the  information
specified in Part I will be delivered to the participants in the plan covered by
this registration  statement as required by Rule 428(b).  Such documents are not
being filed with the Securities and Exchange  Commission (the  "Commission")  as
part of this registration statement or as prospectuses or prospectus supplements
pursuant to Rule 424.


                                     PART II
               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

ITEM 3     INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

         The following  documents  filed with the Commission by the  registrant,
Dendrite International, Inc., a New Jersey corporation (the "Company") (File No.
0-26138),  pursuant to the  Securities  Exchange  Act of 1934,  as amended  (the
"Exchange Act"), are incorporated by reference in this registration statement.


    1.   The Company's  Annual  Report on Form 10-K for the year ended  December
         31, 1998, filed with the Commission on March 26, 1999.

    2.   The  Company's  Proxy  Statement  in  connection  with its 1999  Annual
         Meeting of Shareholders, filed with the Commission on April 16, 1999.

    3.   The Company's Quarterly Report on Form 10-Q for the quarter ended March
         31, 1999, filed with the Commission on May 17, 1999.

    4.   The Company's  Quarterly Report on Form 10-Q for the quarter ended June
         30, 1999, filed with the Commission on August 16, 1999.

    5.   The  Company's  Current  Report on Form 8-K dated June 1, 1999,  filed
         with the Commission on June 2, 1999.

         All documents  subsequently  filed by the Company  pursuant to Sections
13(a),  13(c),  14 and  15(d) of the  Exchange  Act,  prior to the  filing  of a
post-effective  amendment which  indicates that all  obligations  under the Plan
have been satisfied or which  deregisters all such  obligations  then remaining,
shall be deemed to be incorporated by reference in this  registration  statement
and to be a part hereof from the date of filing of such documents. Any statement
contained in a document  incorporated  or deemed to be incorporated by reference
herein  shall be  deemed to be  modified  or  superseded  for  purposes  of this
registration statement to the extent that a statement contained herein or in any
other  subsequently  filed document which also is  incorporated  or deemed to be
incorporated by reference herein modifies or supersedes such statement. Any such
statement so modified or superseded  shall not be deemed,  except as so modified
or superseded, to constitute a part of this registration statement.


ITEM 4     DESCRIPTION OF SECURITIES

           Not applicable.

ITEM 5     INTERESTS OF NAMED EXPERTS AND COUNSEL

           Not applicable.

<PAGE>
ITEM 6     INDEMNIFICATION OF DIRECTORS AND OFFICERS

         Section  14A:3-5 of the New Jersey  Business  Corporation Act ("NJBCA")
gives the Company power to indemnify each of its directors and officers  against
expenses and liabilities in connection with any proceeding involving such person
by reason of such person being or having been a director or officer if (a) he or
she acted in good faith and in a manner he or she reasonably  believed to be in,
or not opposed to, the best interests of the Company and (b) with respect to any
criminal  proceeding,  such person had no reasonable cause to believe his or her
conduct  was  unlawful.  However,  in a  proceeding  by or in the  right  of the
Company,  there shall be no  indemnification  in respect of any  liabilities  or
expenses  if the  officer or  director  shall have been  adjudged  liable to the
Company unless the court in such  proceeding  determines such person is entitled
to  indemnification  for  such  liabilities  and/or  expenses.  Furthermore,  no
indemnification  shall be made to or on behalf of a  director  or  officer  if a
judgment  or other  final  adjudication  adverse  to such  director  or  officer
establishes  that his or her acts or  omissions  (a) were in breach of a duty of
loyalty  to the  Company  and its  shareholders,  (b) were not in good  faith or
involved a knowing  violation  of law or (c) resulted in receipt by the director
or officer of an improper personal benefit. The NJBCA defines an act or omission
in breach of a person's duty of loyalty as an act or omission  which that person
knows or believes to be  contrary  to the best  interests  of the Company or its
shareholders  in  connection  with a matter  in  which he or she has a  material
conflict of interest.  If a director or officer is  successful  in a proceeding,
the statute mandates that the Company indemnify such person against expenses.

         The Company's  Restated  Certificate of Incorporation,  as permitted by
New Jersey law,  eliminates the personal liability of the directors and officers
to the Company or its  shareholders  for  monetary  damages for breaches of such
director's  or officer's  duty of care or other duties as a director or officer;
except  liabilities  for any breach of duty based upon an act or omission (a) in
breach of such person's duty of loyalty to the Company or its shareholders,  (b)
not in good faith or involving a knowing  violation  of law or (c)  resulting in
receipt  by such  person of an  improper  personal  benefit.  In  addition,  the
Company's By-laws provide broad indemnification rights to directors and officers
so long as the director or officer  acted in a manner  believed in good faith to
be in or not opposed to the best  interest  of the  Company and with  respect to
criminal  proceedings  if the  director  or officer had no  reasonable  cause to
believe  his  or her  conduct  was  unlawful.  The  Company  believes  that  the
protection provided by these provisions will help the Company attract and retain
qualified individuals to serve as officers and directors.  These provisions also
will limit the remedies  available to a shareholder who is  dissatisfied  with a
Board decision protected by these provisions, and such shareholder's only remedy
may be to bring a suit to prevent the Board's action.

         The Company  maintains a directors' and officers'  liability  insurance
policy.

         As of October 28, 1998,  the Company  entered  into an  Indemnification
Agreement  with each  Director of the  Company,  providing  that,  with  certain
exceptions,  the Company  would hold  harmless and  indemnify  each  Director in
connection with his  directorship  to the extent  permitted under the New Jersey
Business  Corporation  Act. More  specifically,  the  Indemnification  Agreement
provides that the Company is obligated to indemnify  each  Director  against all
reasonable costs,  expenses (including attorneys' fees), fines,  judgments,  and
settlement amounts that such Director may incur in connection with any actual or
threathened action, suit, or proceeding (whether, civil, criminal, investigative
or  administrative)  to which such  Director is, or may be, a party by reason of
his position as Director or as a director,  officer,  employee,  or agent of any
other  company to which such  Director  provides  services at the request of the
Company.

ITEM 7.  EXEMPTION FROM REGISTRATION CLAIMED

         Not Applicable.

<PAGE>

ITEM 8.  EXHIBITS

Exhibit

  No.         Description
------        -----------

3.1           Restated   Certificate  of  Incorporation  of  the  Company  dated
              November 30, 1995 (incorporated by reference to Exhibit 3.1 to the
              Company's Quarterly  Report on Form 10-Q, filed with the
              Commission on July 30, 1996).

3.2           By-laws of the Company,  as amended  (incorporated by reference to
              Exhibit 3.1 to the Company's Quarterly Report on Form 10-Q for the
              quarter  ended  September 30, 1995,  filed with the  Commission on
              November 13, 1995).

4.1           The Dendrite  International,  Inc. Deferred Compensation Plan (the
              "Plan") dated as of September 1, 1998  (incorporated  by reference
              to Exhibit 10.1 to the Company's  Quarterly  Report filed with the
              Commission on August 14, 1998).

4.2           Deferred  Compensation  Plan Trust Agreement dated as of September
              1,  1998  (incorporated  by  reference  to  Exhibit  10.2  to  the
              Company's  Quarterly  Report filed with the Commission  August 14,
              1998).

5.1           Opinion of Pitney,  Hardin, Kipp & Szuch LLP as to the validity of
              the obligations under the Plan.

23.1          Consent of Pitney,  Hardin, Kipp & Szuch LLP (contained in Exhibit
              5.1 attached hereto).

23.2          Consent of Arthur Andersen LLP, independent public accountants.

24.1          Power of Attorney.
------------------------
<PAGE>

ITEM 9.  REQUIRED UNDERTAKINGS

         (a) The undersigned registrant hereby undertakes:

             (1) To file,  during any period in which  offers or sales are being
     made, a post-effective  amendment to this registration statement to include
     any  material  information  with  respect to the plan of  distribution  not
     previously  disclosed in the registration  statement or any material change
     to such information in the registration statement;

             (2) That,  for the purpose of determining  any liability  under the
     Securities Act of 1933, each such post-effective  amendment shall be deemed
     to be a new registration statement relating to the obligations being
     registered therein, and the offering of such obligations at that time shall
     be deemed to be the initial bona fide offering thereof; and

             (3) To  remove  from  registration  by  means  of a  post-effective
     amendment any of the obligations being registered which remain unsold at
     the termination of the offering.

         (b) The undersigned  registrant hereby undertakes that, for purposes of
determining  any liability  under the Securities Act of 1933, each filing of the
registrant's  annual  report  pursuant to Section  13(a) or Section 15(d) of the
Securities  Exchange  Act of  1934  that is  incorporated  by  reference  in the
registration  statement  shall  be  deemed  to be a new  registration  statement
relating  to  the  obligations  offered  therein,   and  the  offering  of  such
obligations  at that time shall be deemed to be the initial  bona fide  offering
thereof.

         (c)  Insofar  as  indemnification  for  liabilities  arising  under the
Securities Act of 1933 may be permitted to directors,  officers and  controlling
persons of the registrant  pursuant to the foregoing  provisions,  or otherwise,
the  registrant  has been  advised  that in the  opinion of the  Securities  and
Exchange  Commission such  indemnification is against public policy as expressed
in the  Securities  Act and is,  therefore,  unenforceable.  In the event that a
claim for  indemnification  against such liabilities  (other than the payment by
the  registrant  of  expenses  incurred  or  paid  by  a  director,  officer  or
controlling  person of the registrant in the  successful  defense of any action,
suit or proceeding) is asserted by such director,  officer or controlling person
in connection with the obligations being registered, the registrant will, unless
in the  opinion  of its  counsel  the matter  has been  settled  by  controlling
precedent,  submit to a court of appropriate  jurisdiction  the question whether
such  indemnification by it is against public policy as expressed in the Act and
will be governed by the final adjudication of such issue.


<PAGE>


                                   SIGNATURES

         Pursuant  to the  requirements  of the  Securities  Act  of  1933,  the
registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-8 and has duly caused this registration
statement  to be  signed  on  its  behalf  by  the  undersigned,  hereunto  duly
authorized,  in the Township of Harding, State of New Jersey, on the 13th day of
December, 1999.

                                                DENDRITE INTERNATIONAL, INC.


                                                By:JOHN E. BAILYE
                                                   ---------------------------
                                                   John E. Bailye
                                                   Chief Executive Officer,
                                                   President and Director



         Pursuant  to the  requirements  of the  Securities  Act of  1933,  this
registration  statement on Form S-8 has been signed by the following
persons in the capacities and on the dates indicated:


NAME                              TITLE                                 DATE
----                              -----                                 ----


           *                      Chief Executive Officer,
-----------------------------     President and Director
     John E. Bailye               (Principal Executive Officer)


           *                      Executive Vice President and
-----------------------------     Chief Financial Officer
    George T. Robson              (Principal Accounting Officer and
                                   Principal Financial Officer)

           *
-----------------------------
   Bernard M. Goldsmith           Director


           *
-----------------------------
    Edward J. Kfoury              Director


           *
-----------------------------
     Paul A. Margolis             Director


           *
-----------------------------
    John H. Martinson             Director


           *
-----------------------------
    Terence H. Osborne            Director




By:  GEORGE T. ROBSON             Attorney in Fact           December 13, 1999
    -----------------------,
     George T. Robson



<PAGE>


                                  EXHIBIT INDEX


Exhibits
   No.        Description
---------     -----------

3.1           Restated   Certificate  of  Incorporation  of  the  Company  dated
              November 30, 1995 (incorporated by reference to Exhibit 3.1 to the
              Company's Quarterly  Report on Form 10-Q, filed with the
              Commission on July 30, 1996).

3.2           By-laws of the Company,  as amended  (incorporated by reference to
              Exhibit 3.1 to the Company's Quarterly Report on Form 10-Q for the
              quarter  ended  September 30, 1995,  filed with the  Commission on
              November 13, 1995).

4.1           The Dendrite  International,  Inc. Deferred Compensation Plan (the
              "Plan") dated as of September 1, 1998  (incorporated  by reference
              to Exhibit 10.1 to the Company's  Quarterly  Report filed with the
              Commission on August 14, 1998).

4.2           Deferred  Compensation  Plan Trust Agreement dated as of September
              1,  1998  (incorporated  by  reference  to  Exhibit  10.2  to  the
              Company's  Quarterly  Report filed with the Commission  August 14,
              1998).

5.1           Opinion of Pitney,  Hardin, Kipp & Szuch LLP as to the validity of
              the obligations under the Plan.

23.1          Consent of Pitney,  Hardin, Kipp & Szuch LLP (contained in Exhibit
              5.1 attached hereto).

23.2          Consent of Arthur Andersen LLP, independent public accountants.

24.1          Power of Attorney.
-----------------------
[{"type": "S-8", "sequence": "1", "description": "REGISTRATION STATEMENT", "secsgml_size_bytes": 19801}]
{"company-data": {"conformed-name": "DENDRITE INTERNATIONAL INC", "cik": "0000880321", "assigned-sic": "7372", "irs-number": "222786386", "state-of-incorporation": "NJ", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-92711", "film-number": "99774089"}, "business-address": {"street1": "1200 MOUNT KEMBLE AVE", "city": "MORRISTOWN", "state": "NJ", "zip": "07960", "phone": "2014251200"}, "mail-address": {"street1": "1200 MOUNT KEMBLE AVE", "city": "MORRISTOWN", "state": "NJ", "zip": "07960-6797"}}
As filed with the Securities and Exchange Commission on December 14, 1999
                                                  Registration No. 333-_________
------------------------------------------------------------------------------

                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                                ----------------

                                    FORM S-8

             REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933

                          DENDRITE INTERNATIONAL, INC.
                          ----------------------------
             (Exact name of registrant as specified in its charter)

                                   New Jersey
                                   ----------
         (State or other jurisdiction of incorporation or organization)

                                   22-2786386
                                   ----------
                      (I.R.S. Employer Identification No.)

             1200 Mount Kemble Avenue, Morristown, New Jersey 07960-6797
             -----------------------------------------------------------
    (Address, including zip code, of registrant's principal executive offices)

                          DENDRITE INTERNATIONAL, INC.
                           DEFERRED COMPENSATION PLAN
                          ----------------------------
                            (Full title of the Plan)

                               CHRISTOPHER J. FRENCH
                 Vice President, General Counsel and Secretary
                          DENDRITE INTERNATIONAL, INC.
                            1200 Mount Kemble Avenue
                        Morristown, New Jersey 07960-6797
                        ---------------------------------
                     (Name and address of agent for service)

                                 (973) 425-1200
                                 --------------
         (Telephone number, including area code, of agent for service)

                                     -------
                                 With a copy to:
                              Warren J. Casey, Esq.
                        Pitney, Hardin, Kipp & Szuch LLP
                                  P.O. Box 1945
                          Morristown, New Jersey 07962
                                 (973) 966-8025
CALCULATION OF REGISTRATION FEE

------------------------- ---------------------- ----------------------- ---------------------- ----------------------
  Title of securities         Amount to be          Proposed Maximum       Proposed Maximum           Amount of
    to be registered           Registered            Offering Price       Aggregate Offering         Registration
                                                      Per Share(1)             Price (2)                 Fee (2)
------------------------- ---------------------- ----------------------- ---------------------- ----------------------
Deferred Compensation
   Obligations (1)          N/A                        N/A                     N/A                     $462.00
------------------------- ---------------------- ----------------------- ---------------------- ----------------------
--------------------------

(1) The Deferred Compensation  Obligations are unsecured obligations of Dendrite
International, Inc. to  pay deferred  compensation  in the future in  accordance
with the terms of the Dendrite International, Inc. Deferred Compensation Plan.

(2) Based upon estimated obligations in the amount of $462.00 used solely for
the purpose of calculating the registration fee.
PART I
              INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS

                                EXPLANATORY NOTE

         As permitted by Rule 428 under the  Securities  Act of 1933, as amended
(the  "Securities  Act"),  this  registration  statement  omits the  information
specified  in Part I of Form  S-8.  The  documents  containing  the  information
specified in Part I will be delivered to the participants in the plan covered by
this registration  statement as required by Rule 428(b).  Such documents are not
being filed with the Securities and Exchange  Commission (the  "Commission")  as
part of this registration statement or as prospectuses or prospectus supplements
pursuant to Rule 424.

                                     PART II
               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

ITEM 3     INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

         The following  documents  filed with the Commission by the  registrant,
Dendrite International, Inc., a New Jersey corporation (the "Company") (File No.
0-26138),  pursuant to the  Securities  Exchange  Act of 1934,  as amended  (the
"Exchange Act"), are incorporated by reference in this registration statement.

    1.   The Company's  Annual  Report on Form 10-K for the year ended  December
         31, 1998, filed with the Commission on March 26, 1999.

    2.   The  Company's  Proxy  Statement  in  connection  with its 1999  Annual
         Meeting of Shareholders, filed with the Commission on April 16, 1999.

    3.   The Company's Quarterly Report on Form 10-Q for the quarter ended March
         31, 1999, filed with the Commission on May 17, 1999.

    4.   The Company's  Quarterly Report on Form 10-Q for the quarter ended June
         30, 1999, filed with the Commission on August 16, 1999.

    5.   The  Company's  Current  Report on Form 8-K dated June 1, 1999,  filed
         with the Commission on June 2, 1999.

         All documents  subsequently  filed by the Company  pursuant to Sections
13(a),  13(c),  14 and  15(d) of the  Exchange  Act,  prior to the  filing  of a
post-effective  amendment which  indicates that all  obligations  under the Plan
have been satisfied or which  deregisters all such  obligations  then remaining,
shall be deemed to be incorporated by reference in this  registration  statement
and to be a part hereof from the date of filing of such documents. Any statement
contained in a document  incorporated  or deemed to be incorporated by reference
herein  shall be  deemed to be  modified  or  superseded  for  purposes  of this
registration statement to the extent that a statement contained herein or in any
other  subsequently  filed document which also is  incorporated  or deemed to be
incorporated by reference herein modifies or supersedes such statement. Any such
statement so modified or superseded  shall not be deemed,  except as so modified
or superseded, to constitute a part of this registration statement.

ITEM 4     DESCRIPTION OF SECURITIES

           Not applicable.

ITEM 5     INTERESTS OF NAMED EXPERTS AND COUNSEL

           Not applicable.
ITEM 6     INDEMNIFICATION OF DIRECTORS AND OFFICERS

         Section  14A:3-5 of the New Jersey  Business  Corporation Act ("NJBCA")
gives the Company power to indemnify each of its directors and officers  against
expenses and liabilities in connection with any proceeding involving such person
by reason of such person being or having been a director or officer if (a) he or
she acted in good faith and in a manner he or she reasonably  believed to be in,
or not opposed to, the best interests of the Company and (b) with respect to any
criminal  proceeding,  such person had no reasonable cause to believe his or her
conduct  was  unlawful.  However,  in a  proceeding  by or in the  right  of the
Company,  there shall be no  indemnification  in respect of any  liabilities  or
expenses  if the  officer or  director  shall have been  adjudged  liable to the
Company unless the court in such  proceeding  determines such person is entitled
to  indemnification  for  such  liabilities  and/or  expenses.  Furthermore,  no
indemnification  shall be made to or on behalf of a  director  or  officer  if a
judgment  or other  final  adjudication  adverse  to such  director  or  officer
establishes  that his or her acts or  omissions  (a) were in breach of a duty of
loyalty  to the  Company  and its  shareholders,  (b) were not in good  faith or
involved a knowing  violation  of law or (c) resulted in receipt by the director
or officer of an improper personal benefit. The NJBCA defines an act or omission
in breach of a person's duty of loyalty as an act or omission  which that person
knows or believes to be  contrary  to the best  interests  of the Company or its
shareholders  in  connection  with a matter  in  which he or she has a  material
conflict of interest.  If a director or officer is  successful  in a proceeding,
the statute mandates that the Company indemnify such person against expenses.

         The Company's  Restated  Certificate of Incorporation,  as permitted by
New Jersey law,  eliminates the personal liability of the directors and officers
to the Company or its  shareholders  for  monetary  damages for breaches of such
director's  or officer's  duty of care or other duties as a director or officer;
except  liabilities  for any breach of duty based upon an act or omission (a) in
breach of such person's duty of loyalty to the Company or its shareholders,  (b)
not in good faith or involving a knowing  violation  of law or (c)  resulting in
receipt  by such  person of an  improper  personal  benefit.  In  addition,  the
Company's By-laws provide broad indemnification rights to directors and officers
so long as the director or officer  acted in a manner  believed in good faith to
be in or not opposed to the best  interest  of the  Company and with  respect to
criminal  proceedings  if the  director  or officer had no  reasonable  cause to
believe  his  or her  conduct  was  unlawful.  The  Company  believes  that  the
protection provided by these provisions will help the Company attract and retain
qualified individuals to serve as officers and directors.  These provisions also
will limit the remedies  available to a shareholder who is  dissatisfied  with a
Board decision protected by these provisions, and such shareholder's only remedy
may be to bring a suit to prevent the Board's action.

         The Company  maintains a directors' and officers'  liability  insurance
policy.

         As of October 28, 1998,  the Company  entered  into an  Indemnification
Agreement  with each  Director of the  Company,  providing  that,  with  certain
exceptions,  the Company  would hold  harmless and  indemnify  each  Director in
connection with his  directorship  to the extent  permitted under the New Jersey
Business  Corporation  Act. More  specifically,  the  Indemnification  Agreement
provides that the Company is obligated to indemnify  each  Director  against all
reasonable costs,  expenses (including attorneys' fees), fines,  judgments,  and
settlement amounts that such Director may incur in connection with any actual or
threathened action, suit, or proceeding (whether, civil, criminal, investigative
or  administrative)  to which such  Director is, or may be, a party by reason of
his position as Director or as a director,  officer,  employee,  or agent of any
other  company to which such  Director  provides  services at the request of the
Company.

ITEM 7.  EXEMPTION FROM REGISTRATION CLAIMED

         Not Applicable.
ITEM 8.  EXHIBITS

Exhibit

  No.         Description
------        -----------

3.1           Restated   Certificate  of  Incorporation  of  the  Company  dated
              November 30, 1995 (incorporated by reference to Exhibit 3.1 to the
              Company's Quarterly  Report on Form 10-Q, filed with the
              Commission on July 30, 1996).

3.2           By-laws of the Company,  as amended  (incorporated by reference to
              Exhibit 3.1 to the Company's Quarterly Report on Form 10-Q for the
              quarter  ended  September 30, 1995,  filed with the  Commission on
              November 13, 1995).

4.1           The Dendrite  International,  Inc. Deferred Compensation Plan (the
              "Plan") dated as of September 1, 1998  (incorporated  by reference
              to Exhibit 10.1 to the Company's  Quarterly  Report filed with the
              Commission on August 14, 1998).

4.2           Deferred  Compensation  Plan Trust Agreement dated as of September
              1,  1998  (incorporated  by  reference  to  Exhibit  10.2  to  the
              Company's  Quarterly  Report filed with the Commission  August 14,
              1998).

5.1           Opinion of Pitney,  Hardin, Kipp & Szuch LLP as to the validity of
              the obligations under the Plan.

23.1          Consent of Pitney,  Hardin, Kipp & Szuch LLP (contained in Exhibit
              5.1 attached hereto).

23.2          Consent of Arthur Andersen LLP, independent public accountants.

24.1          Power of Attorney.
------------------------
ITEM 9.  REQUIRED UNDERTAKINGS

         (a) The undersigned registrant hereby undertakes:

             (1) To file,  during any period in which  offers or sales are being
     made, a post-effective  amendment to this registration statement to include
     any  material  information  with  respect to the plan of  distribution  not
     previously  disclosed in the registration  statement or any material change
     to such information in the registration statement;

             (2) That,  for the purpose of determining  any liability  under the
     Securities Act of 1933, each such post-effective  amendment shall be deemed
     to be a new registration statement relating to the obligations being
     registered therein, and the offering of such obligations at that time shall
     be deemed to be the initial bona fide offering thereof; and

             (3) To  remove  from  registration  by  means  of a  post-effective
     amendment any of the obligations being registered which remain unsold at
     the termination of the offering.

         (b) The undersigned  registrant hereby undertakes that, for purposes of
determining  any liability  under the Securities Act of 1933, each filing of the
registrant's  annual  report  pursuant to Section  13(a) or Section 15(d) of the
Securities  Exchange  Act of  1934  that is  incorporated  by  reference  in the
registration  statement  shall  be  deemed  to be a new  registration  statement
relating  to  the  obligations  offered  therein,   and  the  offering  of  such
obligations  at that time shall be deemed to be the initial  bona fide  offering
thereof.

         (c)  Insofar  as  indemnification  for  liabilities  arising  under the
Securities Act of 1933 may be permitted to directors,  officers and  controlling
persons of the registrant  pursuant to the foregoing  provisions,  or otherwise,
the  registrant  has been  advised  that in the  opinion of the  Securities  and
Exchange  Commission such  indemnification is against public policy as expressed
in the  Securities  Act and is,  therefore,  unenforceable.  In the event that a
claim for  indemnification  against such liabilities  (other than the payment by
the  registrant  of  expenses  incurred  or  paid  by  a  director,  officer  or
controlling  person of the registrant in the  successful  defense of any action,
suit or proceeding) is asserted by such director,  officer or controlling person
in connection with the obligations being registered, the registrant will, unless
in the  opinion  of its  counsel  the matter  has been  settled  by  controlling
precedent,  submit to a court of appropriate  jurisdiction  the question whether
such  indemnification by it is against public policy as expressed in the Act and
will be governed by the final adjudication of such issue.
SIGNATURES

         Pursuant  to the  requirements  of the  Securities  Act  of  1933,  the
registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-8 and has duly caused this registration
statement  to be  signed  on  its  behalf  by  the  undersigned,  hereunto  duly
authorized,  in the Township of Harding, State of New Jersey, on the 13th day of
December, 1999.

                                                DENDRITE INTERNATIONAL, INC.

                                                By:JOHN E. BAILYE
                                                   ---------------------------
                                                   John E. Bailye
                                                   Chief Executive Officer,
                                                   President and Director

         Pursuant  to the  requirements  of the  Securities  Act of  1933,  this
registration  statement on Form S-8 has been signed by the following
persons in the capacities and on the dates indicated:

NAME                              TITLE                                 DATE
----                              -----                                 ----

           *                      Chief Executive Officer,
-----------------------------     President and Director
     John E. Bailye               (Principal Executive Officer)

           *                      Executive Vice President and
-----------------------------     Chief Financial Officer
    George T. Robson              (Principal Accounting Officer and
                                   Principal Financial Officer)

           *
-----------------------------
   Bernard M. Goldsmith           Director

           *
-----------------------------
    Edward J. Kfoury              Director

           *
-----------------------------
     Paul A. Margolis             Director

           *
-----------------------------
    John H. Martinson             Director

           *
-----------------------------
    Terence H. Osborne            Director

By:  GEORGE T. ROBSON             Attorney in Fact           December 13, 1999
    -----------------------,
     George T. Robson
EXHIBIT INDEX

Exhibits
   No.        Description
---------     -----------

3.1           Restated   Certificate  of  Incorporation  of  the  Company  dated
              November 30, 1995 (incorporated by reference to Exhibit 3.1 to the
              Company's Quarterly  Report on Form 10-Q, filed with the
              Commission on July 30, 1996).

3.2           By-laws of the Company,  as amended  (incorporated by reference to
              Exhibit 3.1 to the Company's Quarterly Report on Form 10-Q for the
              quarter  ended  September 30, 1995,  filed with the  Commission on
              November 13, 1995).

4.1           The Dendrite  International,  Inc. Deferred Compensation Plan (the
              "Plan") dated as of September 1, 1998  (incorporated  by reference
              to Exhibit 10.1 to the Company's  Quarterly  Report filed with the
              Commission on August 14, 1998).

4.2           Deferred  Compensation  Plan Trust Agreement dated as of September
              1,  1998  (incorporated  by  reference  to  Exhibit  10.2  to  the
              Company's  Quarterly  Report filed with the Commission  August 14,
              1998).

5.1           Opinion of Pitney,  Hardin, Kipp & Szuch LLP as to the validity of
              the obligations under the Plan.

23.1          Consent of Pitney,  Hardin, Kipp & Szuch LLP (contained in Exhibit
              5.1 attached hereto).

23.2          Consent of Arthur Andersen LLP, independent public accountants.

24.1          Power of Attorney.
-----------------------