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<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE="2">As
filed with the Securities and Exchange Commission on May 7, 2008<BR>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Registration No. 333- </FONT> </P>


<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE="3">UNITED STATES </FONT> <FONT FACE="Arial, Helvetica, Sans-Serif" SIZE="3"><BR> </FONT>
<FONT FACE="Times New Roman, Times, Serif" SIZE="3">SECURITIES AND EXCHANGE COMMISSION </FONT> </H1>


<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE="2">WASHINGTON, D.C. 20549 </FONT> </H1>


<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE="5">FORM S-8 </FONT> </H1>

<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>REGISTRATION STATEMENT<BR>
UNDER <BR> THE SECURITIES ACT OF 1933 </FONT></P>

<CENTER>
<TABLE CELLSPACING="0" CELLPADDING="0" WIDTH="600" ALIGN="CENTER">



 <tr>
<td VALIGN="TOP" COLSPAN="2"><font SIZE="2"> &nbsp;</font></td> </tr> <tr>
 <TD VALIGN="TOP" COLSPAN="2" ALIGN="CENTER"><font SIZE="2"> <FONT STYLE="font-size:24pt"><B>LABORATORY CORPORATION OF</B> <br>
<U>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<b>AMERICA HOLDINGS</B>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U>
 </FONT><br> (Exact name of
registrant as specified in its charter)</font></td> </tr> </TABLE> </CENTER> <p></p>
<font SIZE="2">
</font> <p ALIGN="CENTER"></p>

 <TABLE CELLSPACING="0" CELLPADDING="0" WIDTH="600" ALIGN="CENTER"> <tr>
 <TD WIDTH="46%" VALIGN="TOP" ALIGN="CENTER"><font SIZE="2"><b> Delaware</b></font></td> <TD WIDTH="10%" VALIGN="TOP">&nbsp;</td> <TD WIDTH="44%" VALIGN="TOP" ALIGN="CENTER"><font SIZE="2"><b>13-3757370</b></font></td> </tr> <tr>
<td WIDTH="46%" VALIGN="TOP"> <hr size="1"></td> <td WIDTH="10%" VALIGN="TOP">&nbsp;</td>
<td WIDTH="44%" VALIGN="TOP"> <hr size="1"></td> </tr> <tr>
 <TD WIDTH="46%" VALIGN="TOP" ALIGN="CENTER"><font SIZE="1"> (State or other jurisdiction of incorporation or organization)</font></td>
<td WIDTH="10%" VALIGN="TOP">&nbsp;</td> <TD WIDTH="44%" VALIGN="TOP" ALIGN="CENTER"><font SIZE="1"> (I.R.S. Employer
Identification No.)</font></td> </tr> <tr>
 <td WIDTH="46%" VALIGN="TOP"><font SIZE="2"> &nbsp;</font></td>
<td WIDTH="10%" VALIGN="TOP">&nbsp;</td> <td WIDTH="44%" VALIGN="TOP">&nbsp;</td> </tr> <tr>
 <TD WIDTH="46%" VALIGN="TOP" ALIGN="CENTER"><font SIZE="2"><b> 358 South Main Street, <BR>Burlington, North Carolina
</b></font></td>
<td WIDTH="10%"VALIGN="top">&nbsp;</td> <TD WIDTH="44%" VALIGN="BOTTOM" ALIGN="CENTER"><font SIZE="2"><b> 27215</b></font></td> </tr>
<tr>
 <td WIDTH="46%" VALIGN="TOP"> <hr size="1"></td>
<td WIDTH="10%" VALIGN="TOP">&nbsp;</td> <td WIDTH="44%" VALIGN="TOP">
<hr size="1"></td> </tr> <tr>
<TD WIDTH="46%" VALIGN="TOP" ALIGN="CENTER"><font SIZE="1"> (Address of principal executive offices)
</font></td> <td WIDTH="10%" VALIGN="TOP">&nbsp;</td> <TD WIDTH="44%" VALIGN="TOP" ALIGN="CENTER"><font SIZE="1">
(Zip Code)</font></td>
</tr> <tr>
<td VALIGN="TOP" COLSPAN="3"><font SIZE="2"> &nbsp;</font></td> </tr>
 </TABLE>

 <BR>

<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE="2">Laboratory Corporation
of America Holdings 2008 Stock Incentive Plan<BR>
(Full titles of the plans) </FONT> </P>

<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><B>Bradford T. Smith<BR>
Executive Vice President, Corporate Affairs and Secretary<BR>Laboratory Corporation
of America Holdings<BR>358 South Main Street<BR>Burlington, North Carolina 27215<BR>(336) 229-1127</B>
<BR>(Name and address of agent for service)<BR> </FONT> </P>

<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><B>304-724-3700</B>
<BR>(Telephone number, including area code, of agent for service)<BR> </FONT> </P>

<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE="2">Copy to:<BR> <B>Michael J. Silver<BR>
Hogan &amp; Hartson LLP<BR>111 South Calvert Street, 16<SUP>th</SUP> Floor<BR>Baltimore, Maryland
21202<BR>Telephone: (410) 659-2700<BR>Telecopy: (410)
539-6981</B> </FONT> </P>


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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Indicate  by  check  mark  whether  the  registrant  is a large  accelerated  filer,  an  accelerated  filer, a
non-accelerated  filer, or a smaller reporting company. See the definitions of  "large accelerated  filer," "accelerated  filer," and "smaller reporting company" in Rule 12b-2 of the
Exchange Act. &nbsp;(Check one): </FONT><BR> <FONT SIZE="2">Large accelerated filer </FONT> <FONT FACE="Wingdings">&#254; </FONT>
<FONT SIZE="2">Accelerated filer </FONT> <FONT FACE="Wingdings">&#168; </FONT><BR> <FONT SIZE="2">Non-accelerated filer </FONT> <FONT FACE="Wingdings">&#168; </FONT>
<FONT SIZE="2">(Do not check if a smaller reporting company) </FONT>
<FONT SIZE="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Smaller reporting company </FONT> <FONT FACE="Wingdings">&#168; </FONT>  </p>

<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE="2">CALCULATION OF REGISTRATION FEE </FONT> </H1>

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<TR VALIGN=TOP>
<TD WIDTH="5%" ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><B>Title of securities<BR>
to be registered</B> </FONT></TD>
<TD WIDTH="5%" ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
<B>Amount to be<BR>registered</B></FONT></TD>
<TD WIDTH="5%" ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
<B>Proposed maximum<BR>offering price per share</B></FONT></TD>
<TD WIDTH="5%" ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
<B>Proposed maximum<BR>aggregate offering price</B></FONT></TD>
<TD WIDTH="5%" ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
<B>Amount of<BR>registration fee</B></FONT></TD>
</TR>
</TABLE>
<BR>

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<TR VALIGN=TOP>
<TD WIDTH="5%" ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">Common stock, par value $0.10<BR>
(1) </FONT></TD>
<TD WIDTH="5%" ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
9,371,205 Shares &nbsp;(2)</FONT></TD>
<TD WIDTH="5%" ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
$75.54 &nbsp;(3)</FONT></TD>
<TD WIDTH="5%" ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
$707,900,825.70&nbsp;(3)</FONT></TD>
<TD WIDTH="5%" ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
$27,820.50</FONT></TD>
</TR>
</TABLE>
<BR>

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               <TR VALIGN=TOP>
               <TD ALIGN=RIGHT WIDTH=3%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(1) </FONT></TD>
               <TD ALIGN=LEFT WIDTH=3%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp; </FONT></TD>
               <TD WIDTH=94%><P ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
               Includes associated preferred stock purchase rights for which no separate fee is
               payable pursuant to Rule&nbsp;457(i). </FONT></P></TD>
               </TR>
               </TABLE>
               <BR>

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               <TR VALIGN=TOP>
               <TD ALIGN=RIGHT WIDTH=3%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(2) </FONT></TD>
               <TD ALIGN=LEFT WIDTH=3%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp; </FONT></TD>
               <TD WIDTH=94%><P ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
               Represents shares of common stock that may be issued pursuant to the Laboratory
               Corporation of America Holdings 2008 Stock Incentive Plan (the
               &#147;<B>Plan</B>&#148;). Pursuant to Rule&nbsp;416 under the Securities Act of
               1933, as amended (the &#147;Securities Act&#148;), this Registration Statement
               shall also cover any additional shares of common stock that become issuable
               under the Plan by reason of any stock dividend, stock split, recapitalization or
               any other similar transaction effected without the receipt of consideration that
               results in an increase in the number of our outstanding shares of common stock. </FONT></P></TD>
               </TR>
               </TABLE>
               <BR>

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               <TR VALIGN=TOP>
               <TD ALIGN=RIGHT WIDTH=3%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(3) </FONT></TD>
               <TD ALIGN=LEFT WIDTH=3%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp; </FONT></TD>
               <TD WIDTH=94%><P ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
               Estimated solely for the purpose of calculating the registration fee in
               accordance with Rule 457(h)(1) and (c) under the Securities Act of 1933, as
               amended. The proposed maximum aggregate offering price is based upon the average
               of the high and low sale prices of the Laboratory Corporation of America
               Holdings common stock as reported on the New York Stock Exchange on May 5, 2008. </FONT></P></TD>
               </TR>
               </TABLE>
               <BR>

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<pAGE>

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<A NAME=A032></A>
<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>PART I </FONT></H1>

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<A NAME=A033></A>
<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>INFORMATION REQUIRED
IN THE SECTION 10(a) PROSPECTUS </FONT></H1>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>The documents containing the
information specified in Part I will be delivered in accordance with Rule&nbsp;428(b)(1)
under the Securities Act of 1933, as amended (the &#147;<B>Securities Act</B>&#148;). Such
documents are not required to be, and are not, filed with the Securities and Exchange
Commission (the &#147;<B>Commission</B>&#148;), either as part of this Registration
Statement or as prospectuses or prospectus supplements pursuant to&nbsp;Rule 424 under the
Securities Act. These documents, and the documents incorporated by reference in this
Registration Statement pursuant to Item&nbsp;3 of Part&nbsp;II of this Form&nbsp;S-8,
taken together, constitute a prospectus that meets the requirements of Section&nbsp;10(a)
of the Securities Act. </FONT></P>

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<A NAME=A035></A>
<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>PART II </FONT></H1>

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<A NAME=A036></A>
<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>INFORMATION REQUIRED
IN THE REGISTRATION STATEMENT </FONT></H1>

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<A NAME=A037></A>
<H1 ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Item 3. Incorporation of Documents
by Reference. </FONT></H1>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The
following documents, which have been filed by Laboratory Corporation of America Holdings
(the &#147;<B>Company</B>&#148;) with the Commission, are incorporated in this
Registration Statement by reference: </FONT></P>

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          <TR VALIGN=TOP>
          <TD ALIGN=RIGHT WIDTH=15%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(a) </FONT></TD>
          <TD ALIGN=LEFT WIDTH=85%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;

           The Company&#146;s Annual Report on Form&nbsp;10-K for the year ended December
          31, 2007. </FONT></TD>
          </TR>
          </TABLE>
          <BR>

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          <TR VALIGN=TOP>
          <TD ALIGN=RIGHT WIDTH=15%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(b) </FONT></TD>
          <TD ALIGN=LEFT WIDTH=85%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;

           The Company&#146;s Quarterly Report on Form 10-Q for the quarter ended March
          31, 2008. </FONT></TD>
          </TR>
          </TABLE>
          <BR>

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          <TR VALIGN=TOP>
          <TD ALIGN=RIGHT WIDTH=15%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(c) </FONT></TD>
          <TD ALIGN=LEFT WIDTH=85%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;

           The Company&#146;s Current Reports on Form 8-K filed on January 24, 2008 (as
          amended January 25, 2008, March 4, 2008, March 31, 2008, April 29, 2008 and May 7, 2008. </FONT></TD>
          </TR>
          </TABLE>
          <BR>

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          <TR VALIGN=TOP>
          <TD ALIGN=RIGHT WIDTH=15%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(d) </FONT></TD>
          <TD ALIGN=LEFT WIDTH=85%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;

           The description of the Company&#146;s common stock, filed in the Company&#146;s
          Registration Statement on Form 8-B filed on July&nbsp;1, 1994, as amended by
          Amendment No.&nbsp;1 thereto dated April&nbsp;27, 1995, under the Securities
          Exchange Act of 1934, and the description of the related stock purchase rights
          in the Registration Statement filed on Form 8-A filed on December&nbsp;21, 2001,
          including amendments thereto, and any report filed for the purpose of updating
          such descriptions. </FONT></TD>
          </TR>
          </TABLE>
          <BR>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;All
documents subsequently filed by the Company pursuant to Sections&nbsp;13(a), 13(c), 14 and
15(d) of the Exchange Act, prior to the filing of a post-effective amendment which
indicates that all securities offered hereby have been sold or which deregisters all
securities then remaining unsold, shall be deemed to be incorporated by reference herein
and to be a part hereof from the date of filing of such documents. </FONT></P>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Any
statement contained in a document incorporated or deemed to be incorporated by reference
herein shall be deemed to be modified or superseded for purposes of this Registration
Statement to the extent that a statement contained herein or in any other subsequently
filed document which also is or is deemed to be incorporated by reference herein modifies
or supersedes such statement. Any statement so modified or superseded shall not be deemed,
except as so modified or superseded, to constitute a part of this Registration Statement. </FONT></P>

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<A NAME=A038></A>
<H1 ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Item 4. Description of
Securities. </FONT></H1>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not
applicable. </FONT></P>


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<A NAME=A039></A>
<H1 ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Item 5. Interests of
Named Experts and Counsel. </FONT></H1>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not
applicable. </FONT></P>

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<A NAME=A040></A>
<H1 ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Item 6. Indemnification
of Directors and Officers. </FONT></H1>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;As
authorized by Section&nbsp;145 of the General Corporation Law of the State of Delaware
(&#147;Delaware Corporation Law&#148;), each director and officer of the Registrant may be
indemnified by the Registrant against expenses (including attorney&#146;s fees, judgments,
fines, and amounts paid in settlement) actually and reasonably incurred in connection with
the defense or settlement of any threatened, pending, or completed legal proceedings in
which he/she is involved by reason of the fact that he/she is or was a director or officer
of the Registrant; provided that he/she acted in good faith and in a manner that he/she
reasonably believed to be in or not opposed to the best interest of the Registrant; and,
with respect to any criminal action or proceeding, that he/she had no reasonable cause to
believe that his/her conduct was unlawful. If the legal proceeding, however, is by or in
the right of the Registrant, the director or officer may not be indemnified in respect of
any claim, issue, or matter as to which he shall have </FONT></P>


<p style=' margin-bottom:0pt; margin-top:0pt;text-align:center;'><font size=2>II-1</font></p>


<br>
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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;adjudged
 to be liable for negligence or misconduct in the performance of his duty to the Registrant unless a court
 determines otherwise. </FONT></P>

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     <P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;Section&nbsp;102(b)(7)
          of the Delaware Corporation Law provides that a corporation may eliminate or
          limit the personal liability of a director to the corporation or its
          stockholders for monetary damages for breach of fiduciary duty as a director,
          provided that such provision shall not eliminate or limit the liability of a
          director (i)&nbsp;for any breach of the director&#146;s duty of loyalty to the
          corporation or its stockholders, (ii)&nbsp;for acts or omissions not in good
          faith or which involve intentional misconduct or a knowing violation of law,
          (iii)&nbsp;for willful or negligent conduct in paying dividends or repurchasing
          stock out of other than lawfully available funds, or (iv)&nbsp;for any
          transaction from which the director derived an improper personal benefit. No
          such provision shall eliminate or limit the liability of a director for any act
          or omission occurring prior to the date when such provision becomes effective. </FONT></P>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Article
Six of the Certificate of Incorporation of the Registrant provides that no director of the
Registrant shall be personally liable to the Registrant or its stockholders for monetary
damages for any breach of his fiduciary duty as director; provided, however, that such
clause shall not apply to any liability of a director (i)&nbsp;for any breach of such
director&#146;s duty of loyalty to the Registrant or its stockholders, (ii)&nbsp;for acts
or omissions not in good faith or which involve intentional misconduct or a knowing
violation of law, (iii)&nbsp;pursuant to Section&nbsp;174 of the Delaware Corporation Law
or (iv)&nbsp;for any transaction from which the director derived an improper personal
benefit. In addition, the provisions of Article VII of the Registrant&#146;s By-laws
provide that the Registrant shall indemnify persons entitled to be indemnified to the
fullest extent permitted by the Delaware Corporation Law. </FONT></P>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The
Registrant maintains policies of officers&#146; and directors&#146; liability insurance in
respect of acts or omissions of current and former officers and directors of the
Registrant, its subsidiaries, and &#147;constituent&#148; companies that have been merged
with the Registrant. </FONT></P>

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<A NAME=A041></A>
<H1 ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Item 7. Exemption from
Registration Claimed. </FONT></H1>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not
applicable. </FONT></P>


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<A NAME=A042></A>
<H1 ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Item 8. Exhibits. </FONT></H1>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Reference
is made to the attached Exhibit Index, which is incorporated by reference herein. </FONT></P>

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<H1 ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Item 9. Undertakings. </FONT></H1>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
(a)&nbsp;&nbsp;&nbsp;&nbsp;The undersigned registrant hereby undertakes: </FONT></P>

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     <P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1)&nbsp;&nbsp;&nbsp;&nbsp;
          To file, during any period in which offers or sales are being made, a
          post-effective amendment to this Registration Statement: </FONT></P>

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     <P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
(i)&nbsp;&nbsp;&nbsp;&nbsp;
          To include any prospectus required by Section&nbsp;10(a)(3) of the Securities
          Act; </FONT></P>

<!-- MARKER FORMAT-SHEET="Para (List) Indent" FSL="Default" -->
     <P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
(ii)&nbsp;&nbsp;&nbsp;&nbsp;
          To reflect in the prospectus any facts or events arising after the effective date of the Registration Statement (or most
recent post-effective amendment thereof) which, individually or in the aggregate,
represent a fundamental change in the information set forth in the Registration Statement.
Notwithstanding the foregoing, any increase or decrease in volume of securities offered
(if the total dollar value of securities offered would not exceed that which was
registered) and any deviation from the low or high end of the estimated maximum offering
range may be reflected in the form of prospectus filed with the Commission pursuant to
Rule 424(b) if, in the aggregate, the changes in volume and price represent no more than a
20 percent change in the maximum aggregate offering price set forth in the
&#147;Calculation of Registration Fee&#148; table in the effective registration statement;
and </FONT></P>

<!-- MARKER FORMAT-SHEET="Para (List) Indent" FSL="Default" -->
     <P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
(iii)&nbsp;&nbsp;&nbsp;&nbsp;
          To include any material information with respect to the plan of distribution not
          previously disclosed in the Registration Statement or any material change to
          such information in the Registration Statement; </FONT></P>

<p style=' margin-bottom:0pt; margin-top:0pt;text-align:center;'><font size=2>II-2</font></p>



<br>
<HR noshade align="center" width="100%" size="2">
<p style='page-break-before:always'></p>
<pAGE>


<!-- MARKER FORMAT-SHEET="Para (List) Indent" FSL="Default" -->
     <P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>provided, however, that paragraphs
(a)(1)(i) and (a)(1)(ii) do not apply if the Registration Statement is on Form&nbsp;S-8
and the information required to be included in a post-effective amendment by those
paragraphs is contained in periodic reports filed with or furnished to the Commission by
the registrant pursuant to Section&nbsp;13 or Section 15(d) of the Exchange Act that are
incorporated by reference in the Registration Statement. </FONT></P>

<!-- MARKER FORMAT-SHEET="Para (List) Indent" FSL="Default" -->
     <P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2)&nbsp;&nbsp;&nbsp;&nbsp;
          That, for the purpose of determining any liability under the Securities Act,
          each such post-effective amendment shall be deemed to be a new registration
          statement relating to the securities offered therein, and the offering of such
          securities at that time shall be deemed to be the initial bona fide offering
          thereof. </FONT></P>

<!-- MARKER FORMAT-SHEET="Para (List) Indent" FSL="Default" -->
     <P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3)&nbsp;&nbsp;&nbsp;&nbsp;
          To remove from registration by means of a post-effective amendment any of the
          securities being registered which remain unsold at the termination of the
          offering. </FONT></P>

<!-- MARKER FORMAT-SHEET="Para Large Indent" FSL="Default" -->
<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
(b)&nbsp;&nbsp;&nbsp;&nbsp;The undersigned registrant hereby undertakes that, for purposes of determining any
liability under the Securities Act, each filing of the registrant&#146;s annual report
pursuant to Section 13(a) or 15(d) of the Exchange Act (and, where applicable, each filing
of an employee benefit plan&#146;s annual report pursuant to Section 15(d) of the Exchange
Act) that is incorporated by reference in the Registration Statement shall be deemed to be
a new registration statement relating to the securities offered herein, and the offering
of such securities at that time shall be deemed to be the initial bona fide offering
thereof. </FONT></P>

<!-- MARKER FORMAT-SHEET="Para Large Indent" FSL="Default" -->
<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
(c)&nbsp;&nbsp;&nbsp;&nbsp;Insofar as indemnification for liabilities arising under the Securities Act may be
permitted to directors, officers and controlling persons of the registrant pursuant to the
foregoing provisions, or otherwise, the registrant has been advised that in the opinion of
the Commission such indemnification is against public policy as expressed in the
Securities Act and is, therefore, unenforceable. In the event that a claim for
indemnification against such liabilities (other than the payment by the registrant of
expenses incurred or paid by a director, officer or controlling person of the registrant
in the successful defense of any action, suit or proceeding) is asserted by such director,
officer or controlling person in connection with the securities being registered, the
registrant will, unless in the opinion of its counsel the matter has been settled by
controlling precedent, submit to a court of appropriate jurisdiction the question whether
such indemnification by it is against public policy as expressed in the Securities Act and
will be governed by the final adjudication of such issue. </FONT></P>

<p style=' margin-bottom:0pt; margin-top:0pt;text-align:center;'><font size=2>II-3</font></p>


<br>
<HR noshade align="center" width="100%" size="2">
<p style='page-break-before:always'></p>
<pAGE>


<p style=' margin-bottom:0pt; margin-top:0pt;text-align:center;'><font size=2>SIGNATURES</font></p>
<p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>

<p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>



<p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>

<p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;line-height:85%;'><font size=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant
to the requirements of the Securities Act of 1933, the registrant certifies that it has
reasonable grounds to believe that it meets all of the requirements for filing on
Form&nbsp;S-8 and has duly caused this Registration Statement to be signed on its behalf
by the undersigned, thereunto duly authorized, in the City of Burlington, State of North
Carolina, on May 7, 2008.</font></p>

<p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>


<table border="0" cellspacing=0 cellpadding=0 width="406" style=' margin-left:68.25pt;border-collapse:collapse'>
    <tr>
        <td  colspan="3" valign=top >
            <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:0pt;margin-bottom:0pt'><u><font SIZE=2>LABORATORY CORPORATION OF AMERICA HOLDINGS</font></u></p> </td> </tr>
    <tr >
        <td  width="269">
            <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=1>&nbsp;</font></td>
        <td width="79" valign=top >
            <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=2>&nbsp;</font></p> </td>
        <td  width="58">
            <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=1>&nbsp;</font></td> </tr>
    <tr>
        <td width="269" ></td>

        <td width="79" ></td>

        <td width="58" ></td> </tr> </table>

<p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>

<p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>


<table border="0" cellspacing=0 cellpadding=0 width="238" style=' margin-left:3.0in;border-collapse:collapse'>
    <tr>
        <td  colspan="5" valign=top >
            <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=2>By: </font><u><font size=2>/s/ Bradford T. Smith</font></u></p> </td> </tr>
    <tr >
        <td  width="30">
            <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=1>&nbsp;</font></td>
        <td  colspan="2" valign=top >
            <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=2>Bradford T. Smith</font></p> </td>
        <td   colspan="2">
            <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=1>&nbsp;</font></td> </tr>
    <tr >
        <td  width="30">
            <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=1>&nbsp;</font></td>
        <td width="138" valign=top >
            <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=2>Executive Vice President, Corporate Affairs </font></p> </td>
        <td   colspan="3">
            <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=1>&nbsp;</font></td> </tr>
    <tr >
        <td  width="30">
            <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=1>&nbsp;</font></td>
        <td  colspan="3" valign=top >
            <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=2>and Secretary</font></p> </td>
        <td  width="25">
            <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:0pt;margin-bottom:0pt'><font size=1>&nbsp;</font></td> </tr>
    <tr>
        <td width="30" ></td>

        <td width="138" ></td>

        <td width="19" ></td>

        <td width="26" ></td>

        <td width="25" ></td> </tr> </table>

<p style=' margin-bottom:0pt; margin-top:0pt;text-align:justify;'><font size=2>&nbsp;</font></p>

<p style=' margin-bottom:0pt; margin-top:0pt;text-align:justify;'><font size=2>&nbsp;</font></p>

<p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;line-height:85%;'><font size=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant
to the requirements of the Securities Act of 1933, this Registration Statement on
Form&nbsp;S-8 has been signed by the following persons on May 7, 2008 in the capacities
indicated.</font></p>

<p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>

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<TABLE WIDTH=600 CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH="50%" ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><B>Name</B> </FONT></TD>
<TD WIDTH="50%" ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
<B>Title</B></FONT></TD>
</TR>
</TABLE>
<BR>

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<TABLE WIDTH=600 CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><u>
/s/DAVID P. KING
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
 </U><BR>David P. King</FONT></TD>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
President, Chief Executive Officer and Director<BR> (Principle Executive Officer)</FONT></TD>
</TR>
</TABLE>
<BR>
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<TABLE WIDTH=600 CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><u>
/s/ WILLIAM B. HAYES
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
 </U><BR>William B. Hayes</FONT></TD>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Executive Vice President, Chief Financial Officer and Treasurer<BR>(Principle Financial Officer)</FONT></TD>
</TR>
</TABLE>
<BR>
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<TABLE WIDTH=600 CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><u>
/s/ THOMAS P. MAC MAHON
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
 </U><BR>Thomas P. Mac Mahon</FONT></TD>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Chairman of the Board of Directors</FONT></TD>
</TR>
</TABLE>
<BR>
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<TABLE WIDTH=600 CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><u>
/s/ BRADFORD T. SMITH
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
 </U><BR>Bradford T. Smith</FONT></TD>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Director</FONT></TD>
</TR>
</TABLE>
<BR>

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<TABLE WIDTH=600 CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><u>
/s/ KERRII B. ADNERSON*
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
 </U><BR>Kerrii B. Anderson</FONT></TD>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Director</FONT></TD>
</TR>
</TABLE>
<BR>




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<TABLE WIDTH=600 CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><u>
/s/ JEAN-LUC BELINGARD*
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
 </U><BR>Jean-Luc Belingard</FONT></TD>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Director</FONT></TD>
</TR>
</TABLE>
<BR>
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<TABLE WIDTH=600 CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><u>
/s/ WENDY E. LANE*
&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
 </U><BR>Wendy E. Lane </FONT></TD>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Director</FONT></TD>
</TR>
</TABLE>
<BR>
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<TABLE WIDTH=600 CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><u>
/s/ ROBERT E. MITTELSTAEDT, Jr.*
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;
 </U><BR>Robert E. Mittelstaedt, Jr. </FONT></TD>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Director</FONT></TD>
</TR>
</TABLE>
<BR>
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<TABLE WIDTH=600 CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><u>
/s/ ARTHUR H. RUBENSTEIN*
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
 </U><BR>Arthur H. Rubenstein </FONT></TD>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Director</FONT></TD>
</TR>
</TABLE>
<BR>

<p style=' margin-bottom:0pt; margin-top:0pt;text-align:center;'><font size=2>II-4</font></p>


<br>
<HR noshade align="center" width="100%" size="2">
<p style='page-break-before:always'></p>
<pAGE>

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<TABLE WIDTH=600 CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><u>
/s/ M. KEITH WEIKEL*
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
 </U><BR>M. Keith Weikel </FONT></TD>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Director</FONT></TD>
</TR>
</TABLE>
<BR>

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<TABLE WIDTH=600 CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><u>
/s/ R. SANDERS WILLIAMS, M.D.*
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
 </U><BR>R. Sanders Williams, M.D.  </FONT></TD>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Director</FONT></TD>
</TR>
</TABLE>
<BR>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>* Bradford T. Smith, by his signing
his name hereto, does hereby sign this report on behalf of the directors of the Registrant
after whose typed names asterisks appear, pursuant to powers of attorney duly executed by
such directors and filed with the Securities and Exchange Commission. </FONT></P>

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<TR VALIGN=TOP>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><u>
/s/ BRADFORD T. SMITH
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
 </U><BR>Bradford T. Smith<BR>Attorney-in-fact  </FONT></TD>
<TD WIDTH="50%" ALIGN="Left"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
&nbsp;</FONT></TD>
</TR>
</TABLE>

<p style=' margin-bottom:0pt; margin-top:0pt;text-align:justify;'><font size=2>&nbsp;</font></p>

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<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>EXHIBIT INDEX </FONT></H1>

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<TR VALIGN=TOP>
<TD WIDTH="5%" ALIGN="LEFT"><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><B>Exhibit<BR> Number</B> </FONT></TD>
<TD WIDTH="40%" ALIGN="LEFT"><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
<B>Description</B></FONT></TD>
</TR>
</TABLE>
<BR>


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<TD WIDTH=10%><FONT FACE="Times New Roman, Times, Serif" SIZE="2">3.1  </FONT> </TD>
<TD WIDTH=90%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>

 Amended and Restated Certificate of Incorporation of the Company dated May 24, 2001
(incorporated herein by reference to the Company&#146;s Registration Statement on Form
S-3, filed with the Commission on October 19, 2001, File No. 333-71896).</FONT></TD>
</TR>
</TABLE>
<BR>

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<TD WIDTH=10%><FONT FACE="Times New Roman, Times, Serif" SIZE="2">3.2  </FONT> </TD>
<TD WIDTH=95%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Amended and Restated By-Laws of the Company dated April 28, 1995 (incorporated
herein by reference to the Company&#146;s report on Form 8-K, filed with the Commission on
May 12, 1995, File No. 001-11353).</FONT></TD>
</TR>
</TABLE>
<BR>

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<TD WIDTH=10%><FONT FACE="Times New Roman, Times, Serif" SIZE="2">4.1  </FONT> </TD>
<TD WIDTH=90%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Specimen of the Company&#146;s Common Stock Certificate (incorporated herein by
reference to the Company&#146;s Annual Report on Form 10-K for the fiscal year ended
December 31, 2001, File No. 001-11353).</FONT></TD>
</TR>
</TABLE>
<BR>

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<TD WIDTH=10%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>4.2 </FONT></TD>
<TD WIDTH=90%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Rights Agreement dated December 13, 2001 between the Company and American Stock
Transfer &amp; Trust Company, as rights Agent (incorporated herein by reference to the
Company&#146;s Registration Statement on Form 8-A, filed with the Commission on December
21, 2001, File No. 001-11353). </FONT></TD>
</TR>
</TABLE>
<BR>

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<TR VALIGN=TOP>
<TD WIDTH=10%><FONT FACE="Times New Roman, Times, Serif" SIZE="2">10.1  </FONT></TD>
<TD WIDTH=90%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Laboratory Corporation of America Holdings, Inc. 2008 Stock Incentive Plan, incorporated by
                       reference to Annex III of the Company's Definitive Proxy Statement on
                       Schedule 14A dated March 25, 2008 (File No.
                       001-11353).</FONT></TD>
</TR>
</TABLE>
<BR>

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<TD WIDTH=10%><FONT FACE="Times New Roman, Times, Serif" SIZE="2">10.2  </FONT></TD>
<TD WIDTH=90%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Amendment to the Laboratory Corporation of America Holdings, Inc. 2008 Stock Incentive Plan,
                       incorporated by reference to Exhibit 10.2 of the Company's Form 8-K filed on May 7, 2008
                       (File No. 001-11353).</FONT></TD>
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<TD WIDTH=10%><FONT FACE="Times New Roman, Times, Serif" SIZE="2">5.1  </FONT></TD>
<TD WIDTH=90%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Opinion of Bradford T. Smith</FONT></TD>
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<TD WIDTH=10%><FONT FACE="Times New Roman, Times, Serif" SIZE="2">23.1  </FONT></TD>
<TD WIDTH=90%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Consent of PricewaterhouseCoopers LLP</FONT></TD>
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<TD WIDTH=90%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Consent of Bradford T. Smith (included in Exhibit 5.1)</FONT></TD>
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<TD WIDTH=10%><FONT FACE="Times New Roman, Times, Serif" SIZE="2">24.1  </FONT></TD>
<TD WIDTH=90%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Powers of Attorney</FONT></TD>
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[{"type": "S-8", "sequence": "1", "filename": "labcorps8.htm", "secsgml_size_bytes": 48941}]
{"company-data": {"conformed-name": "LABORATORY CORP OF AMERICA HOLDINGS", "cik": "0000920148", "assigned-sic": "8071", "irs-number": "133757370", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-150704", "film-number": "08809542"}, "business-address": {"street1": "358 S MAIN ST", "city": "BURLINGTON", "state": "NC", "zip": "27215", "phone": "3362291127"}, "mail-address": {"street1": "358 S MAIN ST", "city": "BURLINGTON", "state": "NC", "zip": "27215"}, "former-company": {"former-conformed-name": "NATIONAL HEALTH LABORATORIES HOLDINGS INC", "date-changed": "19940314"}}
As
filed with the Securities and Exchange Commission on May 7, 2008
Registration No. 333-
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
FORM S-8
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
LABORATORY CORPORATION OF
AMERICA HOLDINGS
(Exact name of
registrant as specified in its charter)
Delaware
13-3757370
(State or other jurisdiction of incorporation or organization)
(I.R.S. Employer
Identification No.)
358 South Main Street,
Burlington, North Carolina
27215
(Address of principal executive offices)
(Zip Code)
Laboratory Corporation
of America Holdings 2008 Stock Incentive Plan
(Full titles of the plans)
Bradford T. Smith
Executive Vice President, Corporate Affairs and Secretary
Laboratory Corporation
of America Holdings
358 South Main Street
Burlington, North Carolina 27215
(336) 229-1127
(Name and address of agent for service)
304-724-3700
(Telephone number, including area code, of agent for service)
Copy to:
Michael J. Silver
Hogan & Hartson LLP
111 South Calvert Street, 16
th
Floor
Baltimore, Maryland
21202
Telephone: (410) 659-2700
Telecopy: (410)
539-6981
Indicate  by  check  mark  whether  the  registrant  is a large  accelerated  filer,  an  accelerated  filer, a
non-accelerated  filer, or a smaller reporting company. See the definitions of  "large accelerated  filer," "accelerated  filer," and "smaller reporting company" in Rule 12b-2 of the
Exchange Act.  (Check one):
Large accelerated filer
þ
Accelerated filer
¨
Non-accelerated filer
¨
(Do not check if a smaller reporting company)
Smaller reporting company
¨
CALCULATION OF REGISTRATION FEE
Title of securities
to be registered
Amount to be
registered
Proposed maximum
offering price per share
Proposed maximum
aggregate offering price
Amount of
registration fee
Common stock, par value $0.10
(1)
9,371,205 Shares  (2)
$75.54  (3)
$707,900,825.70 (3)
$27,820.50
(1)
Includes associated preferred stock purchase rights for which no separate fee is
               payable pursuant to Rule 457(i).
(2)
Represents shares of common stock that may be issued pursuant to the Laboratory
               Corporation of America Holdings 2008 Stock Incentive Plan (the
               "
Plan
"). Pursuant to Rule 416 under the Securities Act of
               1933, as amended (the "Securities Act"), this Registration Statement
               shall also cover any additional shares of common stock that become issuable
               under the Plan by reason of any stock dividend, stock split, recapitalization or
               any other similar transaction effected without the receipt of consideration that
               results in an increase in the number of our outstanding shares of common stock.
(3)
Estimated solely for the purpose of calculating the registration fee in
               accordance with Rule 457(h)(1) and (c) under the Securities Act of 1933, as
               amended. The proposed maximum aggregate offering price is based upon the average
               of the high and low sale prices of the Laboratory Corporation of America
               Holdings common stock as reported on the New York Stock Exchange on May 5, 2008.
PART I
INFORMATION REQUIRED
IN THE SECTION 10(a) PROSPECTUS
The documents containing the
information specified in Part I will be delivered in accordance with Rule 428(b)(1)
under the Securities Act of 1933, as amended (the "
Securities Act
"). Such
documents are not required to be, and are not, filed with the Securities and Exchange
Commission (the "
Commission
"), either as part of this Registration
Statement or as prospectuses or prospectus supplements pursuant to Rule 424 under the
Securities Act. These documents, and the documents incorporated by reference in this
Registration Statement pursuant to Item 3 of Part II of this Form S-8,
taken together, constitute a prospectus that meets the requirements of Section 10(a)
of the Securities Act.
PART II
INFORMATION REQUIRED
IN THE REGISTRATION STATEMENT
Item 3. Incorporation of Documents
by Reference.
The
following documents, which have been filed by Laboratory Corporation of America Holdings
(the "
Company
") with the Commission, are incorporated in this
Registration Statement by reference:
(a)
The Company's Annual Report on Form 10-K for the year ended December
          31, 2007.
(b)
The Company's Quarterly Report on Form 10-Q for the quarter ended March
          31, 2008.
(c)
The Company's Current Reports on Form 8-K filed on January 24, 2008 (as
          amended January 25, 2008, March 4, 2008, March 31, 2008, April 29, 2008 and May 7, 2008.
(d)
The description of the Company's common stock, filed in the Company's
          Registration Statement on Form 8-B filed on July 1, 1994, as amended by
          Amendment No. 1 thereto dated April 27, 1995, under the Securities
          Exchange Act of 1934, and the description of the related stock purchase rights
          in the Registration Statement filed on Form 8-A filed on December 21, 2001,
          including amendments thereto, and any report filed for the purpose of updating
          such descriptions.
All
documents subsequently filed by the Company pursuant to Sections 13(a), 13(c), 14 and
15(d) of the Exchange Act, prior to the filing of a post-effective amendment which
indicates that all securities offered hereby have been sold or which deregisters all
securities then remaining unsold, shall be deemed to be incorporated by reference herein
and to be a part hereof from the date of filing of such documents.
Any
statement contained in a document incorporated or deemed to be incorporated by reference
herein shall be deemed to be modified or superseded for purposes of this Registration
Statement to the extent that a statement contained herein or in any other subsequently
filed document which also is or is deemed to be incorporated by reference herein modifies
or supersedes such statement. Any statement so modified or superseded shall not be deemed,
except as so modified or superseded, to constitute a part of this Registration Statement.
Item 4. Description of
Securities.
Not
applicable.
Item 5. Interests of
Named Experts and Counsel.
Not
applicable.
Item 6. Indemnification
of Directors and Officers.
As
authorized by Section 145 of the General Corporation Law of the State of Delaware
("Delaware Corporation Law"), each director and officer of the Registrant may be
indemnified by the Registrant against expenses (including attorney's fees, judgments,
fines, and amounts paid in settlement) actually and reasonably incurred in connection with
the defense or settlement of any threatened, pending, or completed legal proceedings in
which he/she is involved by reason of the fact that he/she is or was a director or officer
of the Registrant; provided that he/she acted in good faith and in a manner that he/she
reasonably believed to be in or not opposed to the best interest of the Registrant; and,
with respect to any criminal action or proceeding, that he/she had no reasonable cause to
believe that his/her conduct was unlawful. If the legal proceeding, however, is by or in
the right of the Registrant, the director or officer may not be indemnified in respect of
any claim, issue, or matter as to which he shall have
II-1
adjudged
 to be liable for negligence or misconduct in the performance of his duty to the Registrant unless a court
 determines otherwise.
Section 102(b)(7)
          of the Delaware Corporation Law provides that a corporation may eliminate or
          limit the personal liability of a director to the corporation or its
          stockholders for monetary damages for breach of fiduciary duty as a director,
          provided that such provision shall not eliminate or limit the liability of a
          director (i) for any breach of the director's duty of loyalty to the
          corporation or its stockholders, (ii) for acts or omissions not in good
          faith or which involve intentional misconduct or a knowing violation of law,
          (iii) for willful or negligent conduct in paying dividends or repurchasing
          stock out of other than lawfully available funds, or (iv) for any
          transaction from which the director derived an improper personal benefit. No
          such provision shall eliminate or limit the liability of a director for any act
          or omission occurring prior to the date when such provision becomes effective.
Article
Six of the Certificate of Incorporation of the Registrant provides that no director of the
Registrant shall be personally liable to the Registrant or its stockholders for monetary
damages for any breach of his fiduciary duty as director; provided, however, that such
clause shall not apply to any liability of a director (i) for any breach of such
director's duty of loyalty to the Registrant or its stockholders, (ii) for acts
or omissions not in good faith or which involve intentional misconduct or a knowing
violation of law, (iii) pursuant to Section 174 of the Delaware Corporation Law
or (iv) for any transaction from which the director derived an improper personal
benefit. In addition, the provisions of Article VII of the Registrant's By-laws
provide that the Registrant shall indemnify persons entitled to be indemnified to the
fullest extent permitted by the Delaware Corporation Law.
The
Registrant maintains policies of officers' and directors' liability insurance in
respect of acts or omissions of current and former officers and directors of the
Registrant, its subsidiaries, and "constituent" companies that have been merged
with the Registrant.
Item 7. Exemption from
Registration Claimed.
Not
applicable.
Item 8. Exhibits.
Reference
is made to the attached Exhibit Index, which is incorporated by reference herein.
Item 9. Undertakings.
(a)    The undersigned registrant hereby undertakes:
(1)    
          To file, during any period in which offers or sales are being made, a
          post-effective amendment to this Registration Statement:
(i)    
          To include any prospectus required by Section 10(a)(3) of the Securities
          Act;
(ii)    
          To reflect in the prospectus any facts or events arising after the effective date of the Registration Statement (or most
recent post-effective amendment thereof) which, individually or in the aggregate,
represent a fundamental change in the information set forth in the Registration Statement.
Notwithstanding the foregoing, any increase or decrease in volume of securities offered
(if the total dollar value of securities offered would not exceed that which was
registered) and any deviation from the low or high end of the estimated maximum offering
range may be reflected in the form of prospectus filed with the Commission pursuant to
Rule 424(b) if, in the aggregate, the changes in volume and price represent no more than a
20 percent change in the maximum aggregate offering price set forth in the
"Calculation of Registration Fee" table in the effective registration statement;
and
(iii)    
          To include any material information with respect to the plan of distribution not
          previously disclosed in the Registration Statement or any material change to
          such information in the Registration Statement;
II-2
provided, however, that paragraphs
(a)(1)(i) and (a)(1)(ii) do not apply if the Registration Statement is on Form S-8
and the information required to be included in a post-effective amendment by those
paragraphs is contained in periodic reports filed with or furnished to the Commission by
the registrant pursuant to Section 13 or Section 15(d) of the Exchange Act that are
incorporated by reference in the Registration Statement.
(2)    
          That, for the purpose of determining any liability under the Securities Act,
          each such post-effective amendment shall be deemed to be a new registration
          statement relating to the securities offered therein, and the offering of such
          securities at that time shall be deemed to be the initial bona fide offering
          thereof.
(3)    
          To remove from registration by means of a post-effective amendment any of the
          securities being registered which remain unsold at the termination of the
          offering.
(b)    The undersigned registrant hereby undertakes that, for purposes of determining any
liability under the Securities Act, each filing of the registrant's annual report
pursuant to Section 13(a) or 15(d) of the Exchange Act (and, where applicable, each filing
of an employee benefit plan's annual report pursuant to Section 15(d) of the Exchange
Act) that is incorporated by reference in the Registration Statement shall be deemed to be
a new registration statement relating to the securities offered herein, and the offering
of such securities at that time shall be deemed to be the initial bona fide offering
thereof.
(c)    Insofar as indemnification for liabilities arising under the Securities Act may be
permitted to directors, officers and controlling persons of the registrant pursuant to the
foregoing provisions, or otherwise, the registrant has been advised that in the opinion of
the Commission such indemnification is against public policy as expressed in the
Securities Act and is, therefore, unenforceable. In the event that a claim for
indemnification against such liabilities (other than the payment by the registrant of
expenses incurred or paid by a director, officer or controlling person of the registrant
in the successful defense of any action, suit or proceeding) is asserted by such director,
officer or controlling person in connection with the securities being registered, the
registrant will, unless in the opinion of its counsel the matter has been settled by
controlling precedent, submit to a court of appropriate jurisdiction the question whether
such indemnification by it is against public policy as expressed in the Securities Act and
will be governed by the final adjudication of such issue.
II-3
SIGNATURES
Pursuant
to the requirements of the Securities Act of 1933, the registrant certifies that it has
reasonable grounds to believe that it meets all of the requirements for filing on
Form S-8 and has duly caused this Registration Statement to be signed on its behalf
by the undersigned, thereunto duly authorized, in the City of Burlington, State of North
Carolina, on May 7, 2008.
LABORATORY CORPORATION OF AMERICA HOLDINGS
By:
/s/ Bradford T. Smith
Bradford T. Smith
Executive Vice President, Corporate Affairs
and Secretary
Pursuant
to the requirements of the Securities Act of 1933, this Registration Statement on
Form S-8 has been signed by the following persons on May 7, 2008 in the capacities
indicated.
Name
Title
/s/DAVID P. KING
David P. King
President, Chief Executive Officer and Director
(Principle Executive Officer)
/s/ WILLIAM B. HAYES
William B. Hayes
Executive Vice President, Chief Financial Officer and Treasurer
(Principle Financial Officer)
/s/ THOMAS P. MAC MAHON
Thomas P. Mac Mahon
Chairman of the Board of Directors
/s/ BRADFORD T. SMITH
Bradford T. Smith
Director
/s/ KERRII B. ADNERSON*
Kerrii B. Anderson
Director
/s/ JEAN-LUC BELINGARD*
Jean-Luc Belingard
Director
/s/ WENDY E. LANE*
Wendy E. Lane
Director
/s/ ROBERT E. MITTELSTAEDT, Jr.*
Robert E. Mittelstaedt, Jr.
Director
/s/ ARTHUR H. RUBENSTEIN*
Arthur H. Rubenstein
Director
II-4
/s/ M. KEITH WEIKEL*
M. Keith Weikel
Director
/s/ R. SANDERS WILLIAMS, M.D.*
R. Sanders Williams, M.D.
Director
* Bradford T. Smith, by his signing
his name hereto, does hereby sign this report on behalf of the directors of the Registrant
after whose typed names asterisks appear, pursuant to powers of attorney duly executed by
such directors and filed with the Securities and Exchange Commission.
/s/ BRADFORD T. SMITH
Bradford T. Smith
Attorney-in-fact
EXHIBIT INDEX
Exhibit
Number
Description
3.1
Amended and Restated Certificate of Incorporation of the Company dated May 24, 2001
(incorporated herein by reference to the Company's Registration Statement on Form
S-3, filed with the Commission on October 19, 2001, File No. 333-71896).
3.2
Amended and Restated By-Laws of the Company dated April 28, 1995 (incorporated
herein by reference to the Company's report on Form 8-K, filed with the Commission on
May 12, 1995, File No. 001-11353).
4.1
Specimen of the Company's Common Stock Certificate (incorporated herein by
reference to the Company's Annual Report on Form 10-K for the fiscal year ended
December 31, 2001, File No. 001-11353).
4.2
Rights Agreement dated December 13, 2001 between the Company and American Stock
Transfer & Trust Company, as rights Agent (incorporated herein by reference to the
Company's Registration Statement on Form 8-A, filed with the Commission on December
21, 2001, File No. 001-11353).
10.1
Laboratory Corporation of America Holdings, Inc. 2008 Stock Incentive Plan, incorporated by
                       reference to Annex III of the Company's Definitive Proxy Statement on
                       Schedule 14A dated March 25, 2008 (File No.
                       001-11353).
10.2
Amendment to the Laboratory Corporation of America Holdings, Inc. 2008 Stock Incentive Plan,
                       incorporated by reference to Exhibit 10.2 of the Company's Form 8-K filed on May 7, 2008
                       (File No. 001-11353).
5.1
Opinion of Bradford T. Smith
23.1
Consent of PricewaterhouseCoopers LLP
23.2
Consent of Bradford T. Smith (included in Exhibit 5.1)
24.1
Powers of Attorney
II-5