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<p align="right"><font size="2" color="FF0000"><strong>
As filed with the Securities and Exchange Commission on June 25, 2001<br>
                                               Registration No. 333-________
</strong></p></font>

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<p align="center"><font size="3"><strong>UNITED STATES<br>
SECURITIES AND EXCHANGE COMMISSION<br>
Washington, D.C. 20549</strong></font></p>

<HR align=center SIZE=2 width="25%">
<br>
<p align="center"><font size="5"><strong>FORM S-8</strong></center></font>


<p align="center"><font size="3"><strong>
                             REGISTRATION STATEMENT<br>
                                    Under<br>
                       The Securities Act of 1933
</strong>

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<p align="center"><font size="6" color="#0000FF"><strong>
                         <u> SANGSTAT MEDICAL CORPORATION</u>
</strong></font><br>
<font size="2">
                    (Exact name of registrant as specified in its charter)



<P>&nbsp;
<TABLE COLS=2 WIDTH="100%" >
<TR>
<TD>
<font size="3"><strong>
<CENTER><u>Delaware</u></CENTER>
</font></strong>
</TD>
<TD>
<font size="3"><strong>
<CENTER><u>94-3076-069</u></CENTER>
</font></strong>
</TD>
</TR>
<TR>
<TD>
<font size="2">
<CENTER>&nbsp; (State or Other Jurisdiction of Incorporation or Organization)&nbsp;</CENTER>
</font>
</TD>
<TD>
<font size="2">
<CENTER>(I.R.S. Employer Identification Number)</CENTER>
</font>
</TD>
</TR>
</TABLE>
<BR>

<p align="center"><font size="3"><strong>
                          6300 Dumbarton Circle<br>
                          <u> Fremont, California &nbsp;&nbsp;94555<br>
</strong></font></u><br>

<font size="2">
       (Address of principal executive offices, including zip code)</P>

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<p align="center"><font size="3"><strong>
                     SANGSTAT MEDICAL CORPORATION<br>
                       1993 Stock Option Plan<br>
</strong><font size="2">
                        (Full title of the Plans)
</font></p>
<HR align=center SIZE=2 width="25%">
<br>
<p align="center"><font size="3"><strong>
                               Carole L. Nuechterlein<br>
                                    General Counsel<br>
                    SANGSTAT MEDICAL CORPORATION<br>
                        6300 Dumbarton Circle<br>
                       Fremont, California 94555<br>

</strong><font size="2">
                 (Name and address of agent for service)
</font></p>


<p align="center"><font size="3"><strong>
                                (510) 789-4300<br>
</strong><font size="2">
(Telephone number, including area code, of agent for service)
</font></p>

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<B><FONT SIZE=3><P ALIGN="CENTER">CALCULATION OF REGISTRATION FEE</P></B></FONT>
<TABLE BORDER=0 CELLSPACING=1 CELLPADDING=8 WIDTH=650>
<TR><TD WIDTH="25%" VALIGN="BOTTOM">
<FONT SIZE=2><P ALIGN="CENTER">Title of Securities<br>
to be Registered</FONT></TD>
<TD WIDTH="20%" VALIGN="BOTTOM">
<FONT SIZE=2><P ALIGN="CENTER">Amount to be Registered(1)</FONT></TD>
<TD WIDTH="20%" VALIGN="BOTTOM">
<FONT SIZE=2><P ALIGN="CENTER">Proposed Maximum<br>
Offering<br>
Price per Share(2)</FONT></TD>
<TD WIDTH="20%" VALIGN="BOTTOM">
<FONT SIZE=2><P ALIGN="CENTER">Proposed Maximum<br>
Aggregate<br>
Offering Price(2)</FONT></TD>
<TD WIDTH="15%" VALIGN="BOTTOM">
<FONT SIZE=2><P ALIGN="CENTER">Amount of<br>
Registration Fee</FONT></TD>
</TR>

<TR><TD WIDTH="25%" VALIGN="BOTTOM" HEIGHT=35>
<FONT SIZE=2><P><u>1993 Stock Option Plan</u><br>
Options<br>
Common Stock
(par value $0.001 per share)  </FONT></TD>
<TD WIDTH="20%" VALIGN="BOTTOM" HEIGHT=35>
<FONT SIZE=2><P ALIGN="CENTER">
&nbsp;<br>
400,000<br>
&nbsp;<br>
400,000 shares
</FONT></TD>
<TD WIDTH="20%" VALIGN="BOTTOM" HEIGHT=35>
<FONT SIZE=2><P ALIGN="CENTER">
&nbsp;<br>
$13.77<br>
&nbsp;<br>
&nbsp;
</FONT></TD>
<TD WIDTH="20%" VALIGN="BOTTOM" HEIGHT=35>
<FONT SIZE=2><P ALIGN="CENTER">
&nbsp;<br>
$ 5,508,000<br>
&nbsp;<br>
&nbsp;
</FONT></TD>
<TD WIDTH="15%" VALIGN="BOTTOM" HEIGHT=35>
<FONT SIZE=2><P ALIGN="CENTER">
&nbsp;<br>
$ 1,377<br>
&nbsp;<br>
&nbsp;
</FONT></TD>
</TR>
</TABLE>

<BLOCKQUOTE>
<font size="2">
<P ALIGN="JUSTIFY">(1)&#9;This Registration Statement shall also cover any
additional shares of Common Stock which become issuable under the 1993 Stock
Option Plan or the 1996 Non-Employee Directors Stock Option Plan by reason of
any stock dividend, stock split, recapitalization or other similar transaction
effected without the receipt of consideration which results in an increase in
the number of the outstanding shares of Common Stock of SangStat Medical
Corporation</P>
<P ALIGN="JUSTIFY">(2)&#9;Calculated solely for purposes of this offering under
Rule 457(h) of the Securities Act of 1933, as amended, on the basis of the
average of the high and low prices per share of Common Stock of SangStat Medical
Corporation on June 21, 2001.&nbsp;</P>

</BLOCKQUOTE>

<B><P ALIGN="CENTER">PART II</P>
<P ALIGN="CENTER">Information Required in the Registration Statement</P>
<OL START=3>

</B><U><P ALIGN="JUSTIFY"><LI>Incorporation of Documents by Reference</U>
</LI></P>
<P ALIGN="JUSTIFY">SangStat Medical Corporation ("SangStat") hereby incorporates
by reference into this Registration Statement the following documents previously
filed with the Securities and Exchange Commission (the "SEC"):</P>
<OL TYPE="a">

<P ALIGN="JUSTIFY"><LI>SangStat's Annual Report on Form 10-K for the fiscal year
ended December&nbsp;31, 2000</LI></P>
<P ALIGN="JUSTIFY"><LI>Our Current Report on Form 8-K filed January 8,
2001;</LI></P>
<P ALIGN="JUSTIFY"><LI>Our Current Report on Form 8-K filed February 27,
2001;</LI></P>
<P ALIGN="JUSTIFY"><LI>Our Current Report on Form 8-K filed April 5,
2001;</LI></P>
<P ALIGN="JUSTIFY"><LI>Our Current Report on Form 8-K filed April 23,
2001;</LI></P>
<P ALIGN="JUSTIFY"><LI>Our Current Report on Form 8-K filed May 2,
2001;</LI></P>
<P ALIGN="JUSTIFY"><LI>Our Current Report on Form 8-K filed May 4,
2001;</LI></P>
<P ALIGN="JUSTIFY"><LI>Our Quarterly Report on Form 10-Q for the quarter ended
March 31, 2001;</LI></P>
<P ALIGN="JUSTIFY"><LI>Our Current Report on Form 8-K filed June 21,
2001;</LI></P>
<P ALIGN="JUSTIFY"><LI>SangStat's Registration Statement No. 0-22890 on Form
8-B filed with the SEC on December&nbsp;4, 1995 under Section 12 of the
Securities Exchange Act of 1934 (the "1934 Act") in which there is described the
terms, rights and provisions applicable to SangStat's outstanding Common
Stock.</LI></P></OL>


<P>All reports and definitive proxy or information statements filed under the
Section&nbsp;13(a), 13(c), 14 or 15(d) of the 1934 Act after the date of this
Registration Statement and prior to the filing of a post-effective amendment
which indicates that all securities offered hereby have been sold or which
deregisters all securities then remaining unsold shall be deemed to be
incorporated by reference into this Registration Statement and to be a part
hereof from the date of filing of such documents.</P>
<U><P ALIGN="JUSTIFY"><LI>Description of Securities</LI></P>
</U><P ALIGN="JUSTIFY">Not Applicable.</P>
<U><P ALIGN="JUSTIFY"><LI>Interests of Named Experts and Counsel</LI></P>
</U><P ALIGN="JUSTIFY">Not Applicable.</P>
<U><P ALIGN="JUSTIFY"><LI>Indemnification of Directors and Officers</LI></P>
</U><P ALIGN="JUSTIFY">Section 145 of the Delaware General Corporation Law
authorizes a court to award or a corporation's Board of Directors to grant
indemnification to directors and officers in terms sufficiently broad to permit
such indemnification under certain circumstances for liabilities (including
reimbursement for expenses incurred) arising under the Securities Act of 1933
(the "1933 Act"). SangStat's Bylaws provide for mandatory indemnification of its
directors and permissible indemnification of officers, employees and other
agents to the maximum extent permitted by the Delaware General Corporation Law.
SangStat's Certificate of Incorporation provides that, under the Delaware law,
its directors shall not be liable for monetary damages for breach of their
fiduciary duty as directors to SangStat and its stockholders. This provision in
the Certificate of Incorporation does not eliminate the fiduciary duty of the
directors, and, in appropriate circumstances, equitable remedies such as
injunctive or other forms of non-monetary relief will remain available under
Delaware law. In addition, each director will continue to be subject to
liability for breach of the director's duty of loyalty to SangStat for acts or
omissions not in good faith or involving intentional misconduct, for knowing
violations of law, for actions leading to improper personal benefit to the
director and for payment of dividends or approval of stock repurchases or
redemptions that are unlawful under Delaware law. The provision also does not
affect a director's responsibilities under any other law, such as the federal
securities laws or state or federal environmental laws. SangStat has entered
into Indemnification Agreements with its officers and directors. The
Indemnification Agreements provide SangStat's officers and directors with
further indemnification to the maximum extent permitted by the Delaware General
Corporation Law.</P>
<U><P ALIGN="JUSTIFY"><LI>Exemption from Registration Claimed</LI></P>
</U><P ALIGN="JUSTIFY">Not Applicable.&#9;</P>
<U><P ALIGN="JUSTIFY"><LI>Exhibits</LI></P></U>


<P>&nbsp;
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  <TR vAlign=bottom>
<TD>
<font size="2"><strong>
<CENTER><u>Exhibit Number</u></CENTER>
</font></strong>
</TD>
<TD>
<font size="2"><strong>
<u>Exhibit</u>
</font></strong>
</TD>
</TR>

  <TR vAlign=top>
<TD>
<font size="2">
<P ALIGN="CENTER">&nbsp; 4 &nbsp;&nbsp;</P>
</font>
</TD>
    <TD align=left>
<font size="2">
Instrument Defining Rights of Stockholders.
Reference is made to Registrant's Registration Statement No. 0-22890 on Form 8-B,
which is incorporated herein by reference under the Item 3(c) of this
Registration Statement.
</font>
</TD>
</TR>

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<TD>
<font size="2">
<P ALIGN="CENTER">&nbsp; 5 &nbsp;&nbsp;</P>
</font>
</TD>
    <TD align=left>
<font size="2">
Opinion and consent of Carole L. Nuechterlein
</font>
</TD>
</TR>

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<TD>
<font size="2">
<P ALIGN="CENTER">&nbsp; 23.1</P>
</font>
</TD>
    <TD align=left>
<font size="2">
Deloitte&nbsp;&amp; Touche&nbsp;LLP,  Independent Auditors' Consent.
</font>
</TD>
</TR>

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<TD>
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<P ALIGN="CENTER">&nbsp; 23.2</P>
</font>
</TD>
    <TD align=left>
<font size="2">
Consent of Carole L. Nuechterlein is contained in  Exhibit&nbsp;5.
</font>
</TD>
</TR>

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<TD>
<font size="2">
<P ALIGN="CENTER">&nbsp; 24 &nbsp;&nbsp;</P>
</font>
</TD>
    <TD align=left>
<font size="2">
Power of Attorney. Reference is made to page II-4  of this Registration Statement.
</font>
</TD>
</TR>
</TABLE>


<U><P ALIGN="JUSTIFY"><LI>Undertakings</LI></P><OL START=0>

<OL TYPE="A">

</U><P ALIGN="JUSTIFY"><LI>SangStat hereby undertakes:</LI></P>


<OL>

<P ALIGN="JUSTIFY"><LI>to file, during any period in which offers or sales are
being made, a post-effective amendment to this Registration Statement
</LI></P>

<OL TYPE="i">

<P ALIGN="JUSTIFY"><LI>to include any prospectus required by
Section&nbsp;10(a)(3) of the 1933 Act, </LI></P>
<P ALIGN="JUSTIFY"><LI>to reflect in the prospectus any facts or events arising
after the effective date of this Registration Statement (or the most recent
post-effective amendment thereof) which, individually or in the aggregate,
represent a fundamental change in the information set forth in this Registration
Statement and </LI></P>
<P ALIGN="JUSTIFY"><LI>to include any material information with respect to the
plan of distribution not previously disclosed in this Registration Statement or
any material change to such information in this Registration Statement;
<U>provided</U>, however, that clauses&nbsp;(1)(i) and (1)(ii) shall not apply
if the information required to be included in a post-effective amendment by
those paragraphs is contained in periodic reports filed with or furnished to the
SEC by SangStat under the Section&nbsp;13 or Section&nbsp;15(d) of the 1934 Act
that are incorporated by reference in this Registration Statement;</LI></P>
</OL>


<P ALIGN="JUSTIFY"><LI>that for the purpose of determining any liability under
the 1933 Act each such post-effective amendment shall be deemed to be a new
registration statement relating to the securities offered therein and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof and </LI></P>
<P ALIGN="JUSTIFY"><LI>to remove from registration by means of a post-effective
amendment any of the securities being registered which remain unsold at the
termination of SangStat's 1993 Stock Option Plan and/or 1996 Non-Employee
Directors Stock Option Plan.</LI></P>
</OL>


<P ALIGN="JUSTIFY"><LI>SangStat hereby undertakes that, for purposes of
determining any liability under the 1933 Act, each filing of SangStat's annual
report under the Section&nbsp;13(a) or Section 15(d) of the 1934 Act that is
incorporated by reference in this Registration Statement shall be deemed to be a
new registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.</LI></P>
<P ALIGN="JUSTIFY"><LI>Insofar as indemnification for liabilities arising under
the 1933 Act may be permitted to directors, officers or controlling persons of
SangStat under the indemnification provisions summarized in Item 6 or otherwise,
SangStat has been advised that, in the opinion of the SEC, such indemnification
is against public policy as expressed in the 1933 Act, and is, therefore,
unenforceable. In the event that a claim for indemnification against such
liabilities (other than the payment by SangStat of expenses incurred or paid by
a director, officer or controlling person of SangStat in the successful defense
of any action, suit or proceeding) is asserted by such director, officer or
controlling person in connection with the securities being registered, SangStat
will, unless in the opinion of its counsel the matter has been settled by
controlling precedent, submit to a court of appropriate jurisdiction the
question whether such indemnification by it is against public policy as
expressed in the 1933 Act and will be governed by the final adjudication of such
issue.</LI></P></OL>
</OL>
</OL>

<B><P ALIGN="CENTER">SIGNATURES</P>
</B><P ALIGN="JUSTIFY">Under the requirements of the Securities Act of 1933, as
amended, SangStat certifies that it has reasonable grounds to believe that it
meets all of the requirements for filing on Form S-8 and has duly caused this
Registration Statement to be signed on its behalf by the undersigned, thereunto
duly authorized, in the City of Fremont, State of California on this
25<SUP>th</SUP> day of June, 2001.</P>


<P>
<TABLE border=0 cellPadding=0 cellSpacing=0 width="100%">
  <TR>
    <TD width="38%"></TD>
    <TD width="62%"></TD></TR>
  <TR vAlign=top>
    <TD>&nbsp;</TD>
    <TD align=left><font size="2"><B>
                         SangStat Medical Corporation</B>
</TD></TR></TABLE>


<P>
<TABLE border=0 cellPadding=0 cellSpacing=0 width="100%">
  <TR>
    <TD width="38%"></TD>
    <TD width="2%"></TD>
    <TD width="60%"></TD></TR>
  <TR vAlign=top>
    <TD>&nbsp;</TD>
    <TD><font size="2">By:&nbsp;</TD>
    <TD align=left><font size="2">
/s/ STEPHEN G. DANCE
</TD></TR></TABLE>


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  <TR>
    <TD width="38%"></TD>
    <TD width="62%"></TD></TR>
  <TR vAlign=top>
    <TD>&nbsp;</TD>
    <TD align=left>
      <HR align=left SIZE=1>
    </TD></TR>
  <TR vAlign=top>
    <TD>&nbsp;</TD>
    <TD align=left><font size="2">
Stephen G. Dance
</TD></TR>
  <TR vAlign=top>
    <TD>&nbsp;</TD>
    <TD align=left><font size="2"><I>
                                    Senior Vice President, Finance
  </I></TD></TR></TABLE></P>

<B><U><P ALIGN="CENTER">POWER OF ATTORNEY</P>
</U><P ALIGN="JUSTIFY">KNOW ALL PERSONS BY THESE PRESENTS:</P>
</B><P ALIGN="JUSTIFY">That the undersigned officers and directors of SangStat
Medical Corporation, a Delaware corporation, do hereby constitute and appoint
Jean-Jacques Bienaim&eacute; and Stephen G. Dance, or either of them, the lawful
attorneys-in-fact and agents with full power and authority to do any and all
acts and things and to execute any and all instruments which said attorneys and
agents, and either one of them, determine may be necessary or advisable or
required to enable said corporation to comply with the Securities Act of 1933,
as amended, and any rules or regulations or requirements of the Securities and
Exchange Commission in connection with this Registration Statement. Without
limiting the generality of the foregoing power and authority, the powers granted
include the power and authority to sign the names of the undersigned officers
and directors in the capacities indicated below to this Registration Statement,
to any and all amendments, both pre-effective and post-effective, and
supplements to this Registration Statement, and to any and all instruments or
documents filed as part of or in conjunction with this Registration Statement or
amendments or supplements thereof, and each of the undersigned hereby ratifies
and confirms all that said attorneys and agents, or either one of them, shall do
or cause to be done by virtue hereof. This Power of Attorney may be signed in
several counterparts.</P>
<B><P ALIGN="JUSTIFY">IN WITNESS WHEREOF</B>, each of the undersigned has
executed this Power of Attorney as of the date indicated.</P>
<P>Under the requirements of the Securities Act of 1933, as amended, this
Registration Statement has been signed below by the following persons in the
capacities and on the dates indicated as of June 25, 2001.</P>
<P>&nbsp;</P></FONT>
<TABLE CELLSPACING=0 BORDER=0 CELLPADDING=8 WIDTH=616>
<TR><TD WIDTH="43%" VALIGN="TOP" HEIGHT=16>
<P><U><FONT SIZE=2>Signature</U></FONT></TD>
<TD WIDTH="6%" VALIGN="TOP" HEIGHT=16><P></P></TD>
<TD WIDTH="51%" VALIGN="TOP" HEIGHT=16>
<U><FONT SIZE=2><P>Title</U></FONT></TD>
</TR>
<TR><TD WIDTH="43%" VALIGN="TOP" HEIGHT=66>
<FONT SIZE=2>
<U><P>/s/ Jean-Jacques Bienaim&eacute;&#9;
</U><br>Jean-Jacques Bienaim&eacute;</FONT></TD>
<TD WIDTH="6%" VALIGN="TOP" HEIGHT=66><P></P></TD>
<TD WIDTH="51%" VALIGN="TOP" HEIGHT=66>
<FONT SIZE=2>
<P>Chairman of the Board of Directors, Chief Executive Officer,
Director</FONT></TD>
</TR>
<TR><TD WIDTH="43%" VALIGN="TOP" HEIGHT=66>
<FONT SIZE=2>
<U><P ALIGN="JUSTIFY">/s/ Stephen G. Dance&#9;&#9;
</U><br>Stephen G. Dance, CPA, FCA</FONT></TD>
<TD WIDTH="6%" VALIGN="TOP" HEIGHT=66><P></P></TD>
<TD WIDTH="51%" VALIGN="TOP" HEIGHT=66>
<FONT SIZE=2>
<P>Senior Vice President, Finance<br>
(Principal Accounting Officer)</FONT></TD>
</TR>
<TR><TD WIDTH="43%" VALIGN="TOP" HEIGHT=66>
<FONT SIZE=2><U><P>/s/ Fredric J. Feldman&#9;&#9;
</U><br>Fredric J. Feldman, Ph.D.</FONT></TD>
<TD WIDTH="6%" VALIGN="TOP" HEIGHT=66><P></P></TD>
<TD WIDTH="51%" VALIGN="TOP" HEIGHT=66>
<FONT SIZE=2>
<P>Director</FONT></TD>
</TR>
<TR><TD WIDTH="43%" VALIGN="TOP" HEIGHT=66>
<FONT SIZE=2>
<U><P>/s/ Elizabeth Greetham&#9;&#9;
</U><br>Elizabeth Greetham</FONT></TD>
<TD WIDTH="6%" VALIGN="TOP" HEIGHT=66><P></P></TD>
<TD WIDTH="51%" VALIGN="TOP" HEIGHT=66>
<FONT SIZE=2>
<P>Director</FONT></TD>
</TR>
<TR><TD WIDTH="43%" VALIGN="TOP" HEIGHT=82>
<FONT SIZE=2>
<U>/s/ Richard D. Murdock&#9;&#9;
</U><br>Richard D. Murdock</FONT></TD>
<TD WIDTH="6%" VALIGN="TOP" HEIGHT=82><P></P></TD>
<TD WIDTH="51%" VALIGN="TOP" HEIGHT=82>
<FONT SIZE=2>
<P>Director</FONT></TD>
</TR>
<TR><TD WIDTH="43%" VALIGN="TOP" HEIGHT=82>
<FONT SIZE=2>
<U><P>/s/ Andrew Perlman&#9;&#9;
</U><br>Andrew Perlman, M.D., Ph.D.</FONT></TD>
<TD WIDTH="6%" VALIGN="TOP" HEIGHT=82><P></P></TD>
<TD WIDTH="51%" VALIGN="TOP" HEIGHT=82>
<FONT SIZE=2>
<P>Director</FONT></TD>
</TR>
<TR><TD WIDTH="43%" VALIGN="TOP" HEIGHT=82>
<FONT SIZE=2>
<U><P>/s/ Vincent Worms&#9;&#9;
</U><br>Vincent Worms</FONT></TD>
<TD WIDTH="6%" VALIGN="TOP" HEIGHT=82><P></P></TD>
<TD WIDTH="51%" VALIGN="TOP" HEIGHT=82>
<FONT SIZE=2>
<P>Director</FONT></TD>
</TR>
</TABLE>

<FONT SIZE=2><P>&nbsp;</P>
<B><P ALIGN="CENTER">EXHIBIT INDEX</P> </B>


<P>&nbsp;
<TABLE COLS=2 WIDTH="75%" >
  <TR vAlign=bottom>
<TD>
<font size="2"><strong>
<CENTER><u>Exhibit Number</u></CENTER>
</font></strong>
</TD>
<TD>
<font size="2"><strong>
<u>Exhibit</u>
</font></strong>
</TD>
</TR>

  <TR vAlign=top>
<TD>
<font size="2">
<P ALIGN="CENTER">&nbsp; 4 &nbsp;&nbsp;</P>
</font>
</TD>
    <TD align=left>
<font size="2">
Instrument Defining Rights of Stockholders.
Reference is made to Registrant's Registration Statement No. 0-22890 on Form 8-B,
which is incorporated herein by reference under the Item 3(c) of this
Registration Statement.
</font>
</TD>
</TR>

  <TR vAlign=top>
<TD>
<font size="2">
<P ALIGN="CENTER">&nbsp; 5 &nbsp;&nbsp;</P>
</font>
</TD>
    <TD align=left>
<font size="2">
Opinion and consent of Carole L. Nuechterlein
</font>
</TD>
</TR>

  <TR vAlign=top>
<TD>
<font size="2">
<P ALIGN="CENTER">&nbsp; 23.1</P>
</font>
</TD>
    <TD align=left>
<font size="2">
Deloitte&nbsp;&amp; Touche&nbsp;LLP,  Independent Auditors' Consent.
</font>
</TD>
</TR>

  <TR vAlign=top>
<TD>
<font size="2">
<P ALIGN="CENTER">&nbsp; 23.2</P>
</font>
</TD>
    <TD align=left>
<font size="2">
Consent of Carole L. Nuechterlein is contained in  Exhibit&nbsp;5.
</font>
</TD>
</TR>

  <TR vAlign=top>
<TD>
<font size="2">
<P ALIGN="CENTER">&nbsp; 24 &nbsp;&nbsp;</P>
</font>
</TD>
    <TD align=left>
<font size="2">
Power of Attorney. Reference is made to page II-4  of this Registration Statement.
</font>
</TD>
</TR>
</TABLE>



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{"company-data": {"conformed-name": "SANGSTAT MEDICAL CORP", "cik": "0000913610", "assigned-sic": "2836", "irs-number": "943076069", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-63784", "film-number": "1666895"}, "business-address": {"street1": "6300 DUMBARTON CIRCLE", "city": "FREMONT", "state": "CA", "zip": "94555", "phone": "5107894300"}, "mail-address": {"street1": "1505 ADAMS DR", "city": "MENLO PARK", "state": "CA", "zip": "94025"}}
062501 S8 DOC
As filed with the Securities and Exchange Commission on June 25, 2001
Registration No. 333-________
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-8
REGISTRATION STATEMENT
Under
The Securities Act of 1933
SANGSTAT MEDICAL CORPORATION
(Exact name of registrant as specified in its charter)
Delaware
94-3076-069
(State or Other Jurisdiction of Incorporation or Organization)
(I.R.S. Employer Identification Number)
6300 Dumbarton Circle
Fremont, California   94555
(Address of principal executive offices, including zip code)
SANGSTAT MEDICAL CORPORATION
1993 Stock Option Plan
(Full title of the Plans)
Carole L. Nuechterlein
General Counsel
SANGSTAT MEDICAL CORPORATION
6300 Dumbarton Circle
Fremont, California 94555
(Name and address of agent for service)
(510) 789-4300
(Telephone number, including area code, of agent for service)
CALCULATION OF REGISTRATION FEE
Title of Securities
to be Registered
Amount to be Registered(1)
Proposed Maximum
Offering
Price per Share(2)
Proposed Maximum
Aggregate
Offering Price(2)
Amount of
Registration Fee
1993 Stock Option Plan
Options
Common Stock
(par value $0.001 per share)
400,000
400,000 shares
$13.77
$ 5,508,000
$ 1,377
(1)	This Registration Statement shall also cover any
additional shares of Common Stock which become issuable under the 1993 Stock
Option Plan or the 1996 Non-Employee Directors Stock Option Plan by reason of
any stock dividend, stock split, recapitalization or other similar transaction
effected without the receipt of consideration which results in an increase in
the number of the outstanding shares of Common Stock of SangStat Medical
Corporation
(2)	Calculated solely for purposes of this offering under
Rule 457(h) of the Securities Act of 1933, as amended, on the basis of the
average of the high and low prices per share of Common Stock of SangStat Medical
Corporation on June 21, 2001.
PART II
Information Required in the Registration Statement
Incorporation of Documents by Reference
SangStat Medical Corporation ("SangStat") hereby incorporates
by reference into this Registration Statement the following documents previously
filed with the Securities and Exchange Commission (the "SEC"):
SangStat's Annual Report on Form 10-K for the fiscal year
ended December 31, 2000
Our Current Report on Form 8-K filed January 8,
2001;
Our Current Report on Form 8-K filed February 27,
2001;
Our Current Report on Form 8-K filed April 5,
2001;
Our Current Report on Form 8-K filed April 23,
2001;
Our Current Report on Form 8-K filed May 2,
2001;
Our Current Report on Form 8-K filed May 4,
2001;
Our Quarterly Report on Form 10-Q for the quarter ended
March 31, 2001;
Our Current Report on Form 8-K filed June 21,
2001;
SangStat's Registration Statement No. 0-22890 on Form
8-B filed with the SEC on December 4, 1995 under Section 12 of the
Securities Exchange Act of 1934 (the "1934 Act") in which there is described the
terms, rights and provisions applicable to SangStat's outstanding Common
Stock.
All reports and definitive proxy or information statements filed under the
Section 13(a), 13(c), 14 or 15(d) of the 1934 Act after the date of this
Registration Statement and prior to the filing of a post-effective amendment
which indicates that all securities offered hereby have been sold or which
deregisters all securities then remaining unsold shall be deemed to be
incorporated by reference into this Registration Statement and to be a part
hereof from the date of filing of such documents.
Description of Securities
Not Applicable.
Interests of Named Experts and Counsel
Not Applicable.
Indemnification of Directors and Officers
Section 145 of the Delaware General Corporation Law
authorizes a court to award or a corporation's Board of Directors to grant
indemnification to directors and officers in terms sufficiently broad to permit
such indemnification under certain circumstances for liabilities (including
reimbursement for expenses incurred) arising under the Securities Act of 1933
(the "1933 Act"). SangStat's Bylaws provide for mandatory indemnification of its
directors and permissible indemnification of officers, employees and other
agents to the maximum extent permitted by the Delaware General Corporation Law.
SangStat's Certificate of Incorporation provides that, under the Delaware law,
its directors shall not be liable for monetary damages for breach of their
fiduciary duty as directors to SangStat and its stockholders. This provision in
the Certificate of Incorporation does not eliminate the fiduciary duty of the
directors, and, in appropriate circumstances, equitable remedies such as
injunctive or other forms of non-monetary relief will remain available under
Delaware law. In addition, each director will continue to be subject to
liability for breach of the director's duty of loyalty to SangStat for acts or
omissions not in good faith or involving intentional misconduct, for knowing
violations of law, for actions leading to improper personal benefit to the
director and for payment of dividends or approval of stock repurchases or
redemptions that are unlawful under Delaware law. The provision also does not
affect a director's responsibilities under any other law, such as the federal
securities laws or state or federal environmental laws. SangStat has entered
into Indemnification Agreements with its officers and directors. The
Indemnification Agreements provide SangStat's officers and directors with
further indemnification to the maximum extent permitted by the Delaware General
Corporation Law.
Exemption from Registration Claimed
Not Applicable.
Exhibits
Exhibit Number
Exhibit
4
Instrument Defining Rights of Stockholders.
Reference is made to Registrant's Registration Statement No. 0-22890 on Form 8-B,
which is incorporated herein by reference under the Item 3(c) of this
Registration Statement.
5
Opinion and consent of Carole L. Nuechterlein
23.1
Deloitte & Touche LLP,  Independent Auditors' Consent.
23.2
Consent of Carole L. Nuechterlein is contained in  Exhibit 5.
24
Power of Attorney. Reference is made to page II-4  of this Registration Statement.
Undertakings
SangStat hereby undertakes:
to file, during any period in which offers or sales are
being made, a post-effective amendment to this Registration Statement
to include any prospectus required by
Section 10(a)(3) of the 1933 Act,
to reflect in the prospectus any facts or events arising
after the effective date of this Registration Statement (or the most recent
post-effective amendment thereof) which, individually or in the aggregate,
represent a fundamental change in the information set forth in this Registration
Statement and
to include any material information with respect to the
plan of distribution not previously disclosed in this Registration Statement or
any material change to such information in this Registration Statement;
provided
, however, that clauses (1)(i) and (1)(ii) shall not apply
if the information required to be included in a post-effective amendment by
those paragraphs is contained in periodic reports filed with or furnished to the
SEC by SangStat under the Section 13 or Section 15(d) of the 1934 Act
that are incorporated by reference in this Registration Statement;
that for the purpose of determining any liability under
the 1933 Act each such post-effective amendment shall be deemed to be a new
registration statement relating to the securities offered therein and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof and
to remove from registration by means of a post-effective
amendment any of the securities being registered which remain unsold at the
termination of SangStat's 1993 Stock Option Plan and/or 1996 Non-Employee
Directors Stock Option Plan.
SangStat hereby undertakes that, for purposes of
determining any liability under the 1933 Act, each filing of SangStat's annual
report under the Section 13(a) or Section 15(d) of the 1934 Act that is
incorporated by reference in this Registration Statement shall be deemed to be a
new registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.
Insofar as indemnification for liabilities arising under
the 1933 Act may be permitted to directors, officers or controlling persons of
SangStat under the indemnification provisions summarized in Item 6 or otherwise,
SangStat has been advised that, in the opinion of the SEC, such indemnification
is against public policy as expressed in the 1933 Act, and is, therefore,
unenforceable. In the event that a claim for indemnification against such
liabilities (other than the payment by SangStat of expenses incurred or paid by
a director, officer or controlling person of SangStat in the successful defense
of any action, suit or proceeding) is asserted by such director, officer or
controlling person in connection with the securities being registered, SangStat
will, unless in the opinion of its counsel the matter has been settled by
controlling precedent, submit to a court of appropriate jurisdiction the
question whether such indemnification by it is against public policy as
expressed in the 1933 Act and will be governed by the final adjudication of such
issue.
SIGNATURES
Under the requirements of the Securities Act of 1933, as
amended, SangStat certifies that it has reasonable grounds to believe that it
meets all of the requirements for filing on Form S-8 and has duly caused this
Registration Statement to be signed on its behalf by the undersigned, thereunto
duly authorized, in the City of Fremont, State of California on this
25
th
day of June, 2001.
SangStat Medical Corporation
By:
/s/ STEPHEN G. DANCE
Stephen G. Dance
Senior Vice President, Finance
POWER OF ATTORNEY
KNOW ALL PERSONS BY THESE PRESENTS:
That the undersigned officers and directors of SangStat
Medical Corporation, a Delaware corporation, do hereby constitute and appoint
Jean-Jacques Bienaimé and Stephen G. Dance, or either of them, the lawful
attorneys-in-fact and agents with full power and authority to do any and all
acts and things and to execute any and all instruments which said attorneys and
agents, and either one of them, determine may be necessary or advisable or
required to enable said corporation to comply with the Securities Act of 1933,
as amended, and any rules or regulations or requirements of the Securities and
Exchange Commission in connection with this Registration Statement. Without
limiting the generality of the foregoing power and authority, the powers granted
include the power and authority to sign the names of the undersigned officers
and directors in the capacities indicated below to this Registration Statement,
to any and all amendments, both pre-effective and post-effective, and
supplements to this Registration Statement, and to any and all instruments or
documents filed as part of or in conjunction with this Registration Statement or
amendments or supplements thereof, and each of the undersigned hereby ratifies
and confirms all that said attorneys and agents, or either one of them, shall do
or cause to be done by virtue hereof. This Power of Attorney may be signed in
several counterparts.
IN WITNESS WHEREOF
, each of the undersigned has
executed this Power of Attorney as of the date indicated.
Under the requirements of the Securities Act of 1933, as amended, this
Registration Statement has been signed below by the following persons in the
capacities and on the dates indicated as of June 25, 2001.
Signature
Title
/s/ Jean-Jacques Bienaimé
Jean-Jacques Bienaimé
Chairman of the Board of Directors, Chief Executive Officer,
Director
/s/ Stephen G. Dance
Stephen G. Dance, CPA, FCA
Senior Vice President, Finance
(Principal Accounting Officer)
/s/ Fredric J. Feldman
Fredric J. Feldman, Ph.D.
Director
/s/ Elizabeth Greetham
Elizabeth Greetham
Director
/s/ Richard D. Murdock
Richard D. Murdock
Director
/s/ Andrew Perlman
Andrew Perlman, M.D., Ph.D.
Director
/s/ Vincent Worms
Vincent Worms
Director
EXHIBIT INDEX
Exhibit Number
Exhibit
4
Instrument Defining Rights of Stockholders.
Reference is made to Registrant's Registration Statement No. 0-22890 on Form 8-B,
which is incorporated herein by reference under the Item 3(c) of this
Registration Statement.
5
Opinion and consent of Carole L. Nuechterlein
23.1
Deloitte & Touche LLP,  Independent Auditors' Consent.
23.2
Consent of Carole L. Nuechterlein is contained in  Exhibit 5.
24
Power of Attorney. Reference is made to page II-4  of this Registration Statement.