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<P ALIGN=RIGHT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>As filed with the
Securities and Exchange Commission on July 29, 2004<BR>
Registration Statement No. 333-_____ </FONT></P>



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<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=3>SECURITIES AND
EXCHANGE COMMISSION </FONT></H1>

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<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Washington, D.C. 20549 </FONT></H1>

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<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>FORM S-8 <BR>
REGISTRATION STATEMENT <BR>
<I>Under</I> <BR>
<I>The Securities Act of 1933</I> </FONT></H1>


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<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=3>MICROTEK MEDICAL
HOLDINGS, INC. </FONT><BR>
<FONT FACE="Times New Roman, Times, Serif" SIZE=2>(Exact name of
registrant as specified in its charter) </FONT></P>


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     <TD WIDTH="50%" ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><B>Georgia</B>
</FONT></TD>
     <TD WIDTH="50%" ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><B>58-1746149</B>
</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">(State or Other Jurisdiction of<BR>
Incorporation or Organization)
</FONT></TD>
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">(I.R.S. Employer<BR>
Identification No.)
</FONT></TD></TR>
</TABLE>




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<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>512 Lehmberg Road <BR>
Columbus, Mississippi 39702 </FONT></H1>

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<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(Address,
including zip code, of registrant&#146;s principal executive offices) </FONT></P>

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<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=3><B>1999 Long-Term
Incentive Plan, As Amended</B> </FONT><BR>
<FONT FACE="Times New Roman, Times, Serif" SIZE=2>(Full Title of Plan) </FONT></P>

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<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2><B>Dan R. Lee</B> <BR>
<B>512 Lehmberg Road <BR>
Columbus, Mississippi  39702 <BR>
(662) 327-1863</B> <BR>
(Name and address, including zip code, and telephone number, including area code, <BR>
of agent for service) </FONT><P>


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<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Copy to: </FONT></H1>

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<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Stephen D. Fox, Esq. <BR>
Arnall Golden Gregory,
LLP <BR>
2800 One Atlantic
Center <BR>
1201 West Peachtree
Street <BR>
Atlanta, Georgia
30309-3450 </FONT></H1>

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<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>CALCULATION OF
REGISTRATION FEE </FONT></H1>

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<TABLE WIDTH="100%" CELLPADDING="0" CELLSPACING="0">
<TR VALIGN="BOTTOM">
     <TH><FONT SIZE="1">Title of each class of<BR>
securities to be registered</FONT><HR WIDTH=95% SIZE=1 COLOR=BLACK NOSHADE></TH>
     <TH><FONT SIZE="1">Amount to be<BR>
registered</FONT><HR WIDTH=95% SIZE=1 COLOR=BLACK NOSHADE></TH>
     <TH><FONT SIZE="1">Proposed maximum<BR>
offering price per<BR>
share<SUP>(1)</SUP></FONT><HR WIDTH=95% SIZE=1 COLOR=BLACK NOSHADE></TH>
     <TH><FONT SIZE="1">Proposed maximum<BR>
aggregate<BR>
offering price(1)</FONT><HR WIDTH=95% SIZE=1 COLOR=BLACK NOSHADE></TH>
     <TH><FONT SIZE="1">Amount of<BR>
registration<BR>
fee</FONT><HR WIDTH=95% SIZE=1 COLOR=BLACK NOSHADE></TH></TR>
<TR VALIGN="TOP">
     <TD WIDTH="28%" ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE="2">Common Stock, $.001 par value
</FONT></TD>
     <TD WIDTH="18%" ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE="2">2,145,000
</FONT></TD>
     <TD WIDTH="18%" ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE="2">$3.97
</FONT></TD>
     <TD WIDTH="18%" ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE="2">$8,515,650
</FONT></TD>
     <TD WIDTH="18%" ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE="2">$1,079
</FONT></TD></TR>
</TABLE>


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          <TD ALIGN=LEFT WIDTH=3%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(1) </FONT></TD>
          <TD WIDTH=97%><P ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
          Estimated solely for purposes of calculating the registration fee pursuant to
          Rule 457 (c) and (h) based on the average of the bid and asked price of the
          Company&#146;s Common Stock on July 26, 2004, as reported by The Nasdaq Stock
          Market. </FONT></P></TD>
          </TR>
          </TABLE>
          <BR>


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<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>PART II </FONT></H1>

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<TR VALIGN=TOP>
<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2><U>Item 3</U>.  </FONT></TD>
<TD WIDTH=95%><FONT FACE="Times New Roman, Times, Serif" SIZE=2><U>Incorporation
of Documents by Reference</U>.  </FONT></TD>
</TR>
</TABLE>
<BR>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The
following documents filed with the Securities and Exchange Commission are hereby
incorporated by reference: </FONT></P>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a)&nbsp;The
Company&#146;s Annual Report on Form 10-K for the year ended December 31,           2003
(File No. 0-24866);  </FONT></P>



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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b)&nbsp;The
Company&#146;s Quarterly Report on Form 10-Q for the quarter ended           March&nbsp;31,
2004 (File No. 0-24866) filed May 10, 2004;  </FONT></P>



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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c)&nbsp;The
description of the Registrant&#146;s Common Stock set forth in the           Registrant&#146;s
Form 8-A Registration Statements (File No. 0-24866) filed           September 27, 1994
and December 20, 1996.  </FONT></P>



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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;All
documents subsequently filed by the Registrant pursuant to Sections 13(a), 13(c), 14 and
15(d) of the Securities Exchange Act of 1934, as amended (the &#147;Exchange Act&#148;),
after the filing hereof and prior to a filing of a post-effective amendment which
indicates that all securities offered hereby have been sold or which de-registers all
securities remaining unsold, shall be deemed to be incorporated by reference herein and to
be a part hereof from the date of the filing of such reports and documents. </FONT></P>

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<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2><U>Item  4</U>.</FONT></TD>
<TD WIDTH=95%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
<U>Description of Securities</U>.  </FONT></TD>
</TR>
</TABLE>
<BR>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not
applicable. </FONT></P>



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<TR VALIGN=TOP>
<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2><U>Item 5</U>.  </FONT></TD>
<TD WIDTH=95%><FONT FACE="Times New Roman, Times, Serif" SIZE=2><U>Interests
of Named Experts and Counsel</U>.  </FONT></TD>
</TR>
</TABLE>
<BR>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not
applicable. </FONT></P>



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<TR VALIGN=TOP>
<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2><U>Item 6</U>.  </FONT></TD>
<TD WIDTH=95%><FONT FACE="Times New Roman, Times, Serif" SIZE=2><U>Indemnification
of Directors and Officers</U>.  </FONT></TD>
</TR>
</TABLE>
<BR>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant
to Sections 14-2-851 through 14-2-857 of the Georgia Business Corporation Code, as
amended, the directors, officers, employees and agents of the Company may, and in some
cases must, be indemnified by the Company under certain circumstances against expenses
and liabilities incurred by or imposed upon them as a result of actions, suits or
proceedings brought against them as directors, officers, employees and agents of the
Company (including actions, suits or proceedings brought against them for violations of
the federal securities laws). Article Nine of the Company&#146;s Bylaws provides for
indemnifications of directors to the fullest extent permitted by the Georgia Business
Corporation Code. These provisions generally mirror Sections 14-2-851 through 14-2-857 of
the Georgia Business Corporation Code.  </FONT></P>


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<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>II-2 </FONT></P>

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<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2><U>Item 7</U>.  </FONT></TD>
<TD WIDTH=95%><FONT FACE="Times New Roman, Times, Serif" SIZE=2><U>Exemption
from Registration Claimed</U>.  </FONT></TD>
</TR>
</TABLE>
<BR>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not
applicable. </FONT></P>



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<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2><U>Item 8</U>.  </FONT></TD>
<TD WIDTH=95%><FONT FACE="Times New Roman, Times, Serif" SIZE=2><U>Exhibits</U>. </FONT></TD>
</TR>
</TABLE>
<BR>


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     <TH ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="1">Exhibit No.</FONT><HR WIDTH=95% SIZE=1 COLOR=BLACK NOSHADE></TH>
     <TH><FONT FACE="Times New Roman, Times, Serif" SIZE="1">Description</FONT><HR WIDTH=95% SIZE=1 COLOR=BLACK NOSHADE></TH></TR>
<TR VALIGN="TOP">
     <TD WIDTH="15%" ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">5
</FONT></TD>
     <TD WIDTH="85%"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Opinion of counsel as to legality of the securities being registered
</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">10(a)
</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1999 Long-Term Incentive Plan, as amended May 19, 2004
</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">23(a)
</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Consent of Arnall Golden  Gregory,  LLP (included in opinion filed as Exhibit 5)
</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">23(b)
</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Consent of KPMG LLP
</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">23(c)
</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Consent of Deloitte &amp; Touche LLP
</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">24
</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Power of Attorney (included on page II-5)</FONT></TD></TR>
</TABLE>
<BR>





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<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2><U>Item 9</U>.  </FONT></TD>
<TD WIDTH=95%><FONT FACE="Times New Roman, Times, Serif" SIZE=2><U>Undertakings</U>.  </FONT></TD>
</TR>
</TABLE>
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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The
undersigned Registrant hereby undertakes as follows:  </FONT></P>



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<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(1) </FONT></TD>
<TD WIDTH=90%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>To
file, during any period in which offers or sales are being made, a
          post-effective amendment to this registration statement:  </FONT></TD>
</TR>
</TABLE>
<BR>



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<TD WIDTH=10%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;</FONT></TD>
<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(i)  </FONT></TD>
<TD WIDTH=85%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>To
include any prospectus required by Section 10(a)(3) of the Act;  </FONT></TD>
</TR>
</TABLE>
<BR>

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               <TD ALIGN=RIGHT WIDTH=12%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(ii) </FONT></TD>
               <TD ALIGN=LEFT WIDTH=3%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp; </FONT></TD>
               <TD WIDTH=85%><P ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
               To reflect in the prospectus any facts or events arising after the effective
               date of the registration statement (or the most recent post-effective amendment
               thereof) which, individually or in aggregate, represent a fundamental change in
               the information set forth in this registration statement; </FONT></P></TD>
               </TR>
               </TABLE>
               <BR>


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<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>II-3 </FONT></P>

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               <TD ALIGN=RIGHT WIDTH=12%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(iii) </FONT></TD>
               <TD ALIGN=LEFT WIDTH=3%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp; </FONT></TD>
               <TD WIDTH=85%><P ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
               To include any material information with respect to the plan of distribution not
               previously disclosed in this registration statement or any material change to
               such information in this registration statement; </FONT></P></TD>
               </TR>
               </TABLE>
               <BR>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2><U>provided</U>, <U>however</U>, that
the undertakings set forth in paragraphs (i) and (ii) above do not apply if the
information required to be included in a post-effective amendment by those paragraphs is
contained in periodic reports filed by the Registrant pursuant to Section 13(a) or Section
15(d) of the Exchange Act that are incorporated by reference in this registration
statement. </FONT></P>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2)&nbsp;That,
for the purpose of determining any liability under the Act, each such
          post-effective amendment shall be deemed to be a new registration statement
          relating to the securities offered therein, and the offering of such securities
          at the time shall be deemed to be the initial bona fide offering thereof.  </FONT></P>



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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3)&nbsp;To
remove from registration by means of a post-effective amendment any of the
          securities being registered which remain unsold at the termination of the
          offering.  </FONT></P>



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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(4)&nbsp;That,
for purposes of determining any liability under the Act each filing of the
          registrant&#146;s annual report pursuant to Section 13(a) or Section 15(d) of
          the Exchange Act (and, where applicable, each filing of an employee benefit
          plan&#146;s annual report pursuant to Section 15(d) of the Exchange Act) that
is           incorporated by reference in this registration statement shall be deemed to
be a           new registration statement relating to the securities offered therein, and
the           offering of such securities at that time shall be deemed to be the initial
bona           fide offering thereof.  </FONT></P>



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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(5)&nbsp;Insofar
as indemnification for liabilities arising under the Act may be           permitted to
directors, officers, and controlling persons of the Registrant           pursuant to the
foregoing provisions or otherwise, the Registrant has been           advised that in the
opinion of the Securities and Exchange Commission such           indemnification is
against public policy as expressed in the Act and is,           therefore, unenforceable.
In the event that a claim for indemnification against           such liabilities (other
than the payment by the Registrant of expenses incurred           or paid by a director,
officer or controlling person of the Registrant in the           successful defense of
any action, suit or proceeding) is asserted by such           director, officer or
controlling person in connection with the securities being           registered, the
Registrant will, unless in the opinion of its counsel the matter           has been
settled by controlling precedent, submit to a court of appropriate           jurisdiction
the question whether such indemnification by it is against public           policy as
expressed in the Act and will be governed by the final adjudication of           such
issue.  </FONT></P>



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<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>[SIGNATURES ON
FOLLOWING PAGE] </FONT></H1>


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<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>II-4 </FONT></P>

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<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2><U>SIGNATURES</U> </FONT></H1>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;In
accordance with the requirements of the Securities Act of 1933, the Registrant certifies
that it has reasonable grounds to believe that it meets all of the requirements of filing
on Form S-8 and authorized this registration statement to be signed on its behalf by the
undersigned, in the City of Columbus, State of Mississippi, on July 29, 2004.  </FONT></P>


<TABLE WIDTH="100%" BORDER="0" CELLPADDING="0" CELLSPACING="0">
<TR VALIGN="TOP">
     <TD WIDTH="50%"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD WIDTH="50%"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">MICROTEK MEDICAL HOLDINGS, INC.
</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;<BR><BR></FONT></TD></TR>
<TR VALIGN="TOP">
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">By:  <U>/s/ Dan R. Lee</U>
</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">Dan R. Lee, President and<BR>
Chief Executive Officer</FONT></TD></TR>
</TABLE>




<!-- MARKER FORMAT-SHEET="Head Center Underline" FSL="Default" -->
<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2><U>POWER OF ATTORNEY</U> </FONT></P>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;KNOW
ALL MEN BY THESE PRESENTS that each person whose signature appears below constitutes and
appoints Dan R. Lee and Roger G. Wilson, and each of them, as his true and lawful
attorneys-in-fact and agents, with full power of substitution and resubstitution, for him
and in his name, place and stead, in any and all capacities, to sign any and all
amendments (including post-effective amendments) to this Registration Statement, and to
file the same with all exhibits thereto, and other documents in connection therewith,
with the Securities and Exchange Commission, granting unto said attorneys-in-fact and
agents, and each of them, full power and authority to do and perform each and every act
and thing requisite and necessary to be done in and about the premises, as fully to all
intents and purposes as he might or could do in person, hereby ratifying and confirming
all that said attorneys-in-fact and agents, or either of them, or their or his substitute
or substitutes, may lawfully do or cause to be done by virtue hereof.  </FONT></P>



<!-- MARKER FORMAT-SHEET="Head Major Center Bold" FSL="Default" -->
<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>[ADDITIONAL SIGNATURES
ON FOLLOWING PAGE] </FONT></H1>


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<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>II-5 </FONT></P>

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<HR SIZE=5 COLOR=GRAY NOSHADE>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant
to the requirements of the Securities Act of 1933, this Registration Statement on Form
S-8 was signed by the following persons in the capacities indicated on July 29, 2004.  </FONT></P>


<TABLE WIDTH="100%" CELLPADDING="0" CELLSPACING="0">
<TR VALIGN="BOTTOM">
     <TH><FONT SIZE="1"><U>SIGNATURE</U></FONT></TH>
     <TH><FONT SIZE="1">&nbsp;</FONT></TH>
     <TH><FONT SIZE="1"><U>TITLE</U></FONT></TH></TR>
<TR VALIGN="TOP">
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD WIDTH="33%"><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><U>/s/ Dan R. Lee</U><BR>
Dan R. Lee
</FONT></TD>
     <TD WIDTH="7%"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD WIDTH="70%"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">President, Chief Executive Officer and Director&nbsp; <BR>(principal
executive officer)
</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><U>/s/ Kenneth F. Davis</U><BR>
Kenneth F. Davis
</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">Director
</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><U>/s/ Michael E. Glasscock, III</U><BR>
Michael E. Glasscock, III
</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">Director
</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><U>/s/ Rosdon Hendrix</U><BR>
Rosdon Hendrix
</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">Director
</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><U>/s/ Gene R. McGrevin</U><BR>
Gene R. McGrevin
</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">Director
</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><U>/s/ Ronald L. Smorada</U><BR>
Ronald L. Smorada
</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">Director
</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><U>/s/ Roger G. Wilson</U><BR>
Roger G. Wilson
</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">Chief Financial Officer, Treasurer and Assistant Secretary<BR>
(principal financial and accounting officer)
</FONT></TD></TR>
</TABLE>





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<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>II-6 </FONT></P>

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<HR SIZE=5 COLOR=GRAY NOSHADE>



<!-- MARKER FORMAT-SHEET="Head Minor Center" FSL="Default" -->
<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>EXHIBIT INDEX </FONT></P>


<TABLE WIDTH="100%" CELLPADDING="0" CELLSPACING="0">
<TR VALIGN="BOTTOM">
     <TH ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="1">Exhibit No.</FONT><HR WIDTH=95% SIZE=1 COLOR=BLACK NOSHADE></TH>
     <TH><FONT FACE="Times New Roman, Times, Serif" SIZE="1">Description</FONT><HR WIDTH=95% SIZE=1 COLOR=BLACK NOSHADE></TH></TR>
<TR VALIGN="TOP">
     <TD WIDTH="15%" ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">5*
</FONT></TD>
     <TD WIDTH="85%"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Opinion of counsel as to legality of the securities being registered
</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">10(a)*
</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1999 Long-Term Incentive Plan, as amended May 19, 2004
</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">23(a)
</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Consent of Arnall Golden  Gregory,  LLP (included in opinion filed as Exhibit 5)
</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">23(b)*
</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Consent of KPMG LLP
</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">23(c)*
</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Consent of Deloitte &amp; Touche LLP
</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;</FONT></TD></TR>
<TR VALIGN="TOP">
     <TD ALIGN="CENTER"><FONT FACE="Times New Roman, Times, Serif" SIZE="2">24
</FONT></TD>
     <TD><FONT FACE="Times New Roman, Times, Serif" SIZE="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Power of Attorney (included on page II-5)</FONT></TD></TR>
</TABLE>
<BR>


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<P>_________________ </P>

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<P ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>* Filed herewith. </FONT></P>


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<P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>II-7 </FONT></P>




</BODY>
</HTML>
[{"type": "S-8", "sequence": "1", "filename": "microteks8704.htm", "description": "FORM S-8", "secsgml_size_bytes": 34912}]
{"company-data": {"conformed-name": "MICROTEK MEDICAL HOLDINGS INC", "cik": "0000929299", "assigned-sic": "3842", "irs-number": "581746149", "state-of-incorporation": "GA", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-117736", "film-number": "04937616"}, "business-address": {"street1": "512 LEHMBERG ROAD", "city": "COLUMBUS", "state": "MS", "zip": "39702", "phone": "(662) 327-1863"}, "mail-address": {"street1": "512 LEHMBERG ROAD", "city": "COLUMBUS", "state": "MS", "zip": "39702"}, "former-company": {"former-conformed-name": "ISOLYSER CO INC /GA/", "date-changed": "19940831"}}
As filed with the
Securities and Exchange Commission on July 29, 2004
Registration Statement No. 333-_____
SECURITIES AND
EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-8
REGISTRATION STATEMENT
Under
The Securities Act of 1933
MICROTEK MEDICAL
HOLDINGS, INC.
(Exact name of
registrant as specified in its charter)
Georgia
58-1746149
(State or Other Jurisdiction of
Incorporation or Organization)
(I.R.S. Employer
Identification No.)
512 Lehmberg Road
Columbus, Mississippi 39702
(Address,
including zip code, of registrant's principal executive offices)
1999 Long-Term
Incentive Plan, As Amended
(Full Title of Plan)
Dan R. Lee
512 Lehmberg Road
Columbus, Mississippi  39702
(662) 327-1863
(Name and address, including zip code, and telephone number, including area code,
of agent for service)
Copy to:
Stephen D. Fox, Esq.
Arnall Golden Gregory,
LLP
2800 One Atlantic
Center
1201 West Peachtree
Street
Atlanta, Georgia
30309-3450
CALCULATION OF
REGISTRATION FEE
Title of each class of
securities to be registered
Amount to be
registered
Proposed maximum
offering price per
share
(1)
Proposed maximum
aggregate
offering price(1)
Amount of
registration
fee
Common Stock, $.001 par value
2,145,000
$3.97
$8,515,650
$1,079
(1)
Estimated solely for purposes of calculating the registration fee pursuant to
          Rule 457 (c) and (h) based on the average of the bid and asked price of the
          Company's Common Stock on July 26, 2004, as reported by The Nasdaq Stock
          Market.
PART II
Item 3
.
Incorporation
of Documents by Reference
.
The
following documents filed with the Securities and Exchange Commission are hereby
incorporated by reference:
(a) The
Company's Annual Report on Form 10-K for the year ended December 31,           2003
(File No. 0-24866);
(b) The
Company's Quarterly Report on Form 10-Q for the quarter ended           March 31,
2004 (File No. 0-24866) filed May 10, 2004;
(c) The
description of the Registrant's Common Stock set forth in the           Registrant's
Form 8-A Registration Statements (File No. 0-24866) filed           September 27, 1994
and December 20, 1996.
All
documents subsequently filed by the Registrant pursuant to Sections 13(a), 13(c), 14 and
15(d) of the Securities Exchange Act of 1934, as amended (the "Exchange Act"),
after the filing hereof and prior to a filing of a post-effective amendment which
indicates that all securities offered hereby have been sold or which de-registers all
securities remaining unsold, shall be deemed to be incorporated by reference herein and to
be a part hereof from the date of the filing of such reports and documents.
Item  4
.
Description of Securities
.
Not
applicable.
Item 5
.
Interests
of Named Experts and Counsel
.
Not
applicable.
Item 6
.
Indemnification
of Directors and Officers
.
Pursuant
to Sections 14-2-851 through 14-2-857 of the Georgia Business Corporation Code, as
amended, the directors, officers, employees and agents of the Company may, and in some
cases must, be indemnified by the Company under certain circumstances against expenses
and liabilities incurred by or imposed upon them as a result of actions, suits or
proceedings brought against them as directors, officers, employees and agents of the
Company (including actions, suits or proceedings brought against them for violations of
the federal securities laws). Article Nine of the Company's Bylaws provides for
indemnifications of directors to the fullest extent permitted by the Georgia Business
Corporation Code. These provisions generally mirror Sections 14-2-851 through 14-2-857 of
the Georgia Business Corporation Code.
II-2
Item 7
.
Exemption
from Registration Claimed
.
Not
applicable.
Item 8
.
Exhibits
.
Exhibit No.
Description
5
Opinion of counsel as to legality of the securities being registered
10(a)
1999 Long-Term Incentive Plan, as amended May 19, 2004
23(a)
Consent of Arnall Golden  Gregory,  LLP (included in opinion filed as Exhibit 5)
23(b)
Consent of KPMG LLP
23(c)
Consent of Deloitte & Touche LLP
24
Power of Attorney (included on page II-5)
Item 9
.
Undertakings
.
The
undersigned Registrant hereby undertakes as follows:
(1)
To
file, during any period in which offers or sales are being made, a
          post-effective amendment to this registration statement:
(i)
To
include any prospectus required by Section 10(a)(3) of the Act;
(ii)
To reflect in the prospectus any facts or events arising after the effective
               date of the registration statement (or the most recent post-effective amendment
               thereof) which, individually or in aggregate, represent a fundamental change in
               the information set forth in this registration statement;
II-3
(iii)
To include any material information with respect to the plan of distribution not
               previously disclosed in this registration statement or any material change to
               such information in this registration statement;
provided
,
however
, that
the undertakings set forth in paragraphs (i) and (ii) above do not apply if the
information required to be included in a post-effective amendment by those paragraphs is
contained in periodic reports filed by the Registrant pursuant to Section 13(a) or Section
15(d) of the Exchange Act that are incorporated by reference in this registration
statement.
(2) That,
for the purpose of determining any liability under the Act, each such
          post-effective amendment shall be deemed to be a new registration statement
          relating to the securities offered therein, and the offering of such securities
          at the time shall be deemed to be the initial bona fide offering thereof.
(3) To
remove from registration by means of a post-effective amendment any of the
          securities being registered which remain unsold at the termination of the
          offering.
(4) That,
for purposes of determining any liability under the Act each filing of the
          registrant's annual report pursuant to Section 13(a) or Section 15(d) of
          the Exchange Act (and, where applicable, each filing of an employee benefit
          plan's annual report pursuant to Section 15(d) of the Exchange Act) that
is           incorporated by reference in this registration statement shall be deemed to
be a           new registration statement relating to the securities offered therein, and
the           offering of such securities at that time shall be deemed to be the initial
bona           fide offering thereof.
(5) Insofar
as indemnification for liabilities arising under the Act may be           permitted to
directors, officers, and controlling persons of the Registrant           pursuant to the
foregoing provisions or otherwise, the Registrant has been           advised that in the
opinion of the Securities and Exchange Commission such           indemnification is
against public policy as expressed in the Act and is,           therefore, unenforceable.
In the event that a claim for indemnification against           such liabilities (other
than the payment by the Registrant of expenses incurred           or paid by a director,
officer or controlling person of the Registrant in the           successful defense of
any action, suit or proceeding) is asserted by such           director, officer or
controlling person in connection with the securities being           registered, the
Registrant will, unless in the opinion of its counsel the matter           has been
settled by controlling precedent, submit to a court of appropriate           jurisdiction
the question whether such indemnification by it is against public           policy as
expressed in the Act and will be governed by the final adjudication of           such
issue.
[SIGNATURES ON
FOLLOWING PAGE]
II-4
SIGNATURES
In
accordance with the requirements of the Securities Act of 1933, the Registrant certifies
that it has reasonable grounds to believe that it meets all of the requirements of filing
on Form S-8 and authorized this registration statement to be signed on its behalf by the
undersigned, in the City of Columbus, State of Mississippi, on July 29, 2004.
MICROTEK MEDICAL HOLDINGS, INC.
By:
/s/ Dan R. Lee
Dan R. Lee, President and
Chief Executive Officer
POWER OF ATTORNEY
KNOW
ALL MEN BY THESE PRESENTS that each person whose signature appears below constitutes and
appoints Dan R. Lee and Roger G. Wilson, and each of them, as his true and lawful
attorneys-in-fact and agents, with full power of substitution and resubstitution, for him
and in his name, place and stead, in any and all capacities, to sign any and all
amendments (including post-effective amendments) to this Registration Statement, and to
file the same with all exhibits thereto, and other documents in connection therewith,
with the Securities and Exchange Commission, granting unto said attorneys-in-fact and
agents, and each of them, full power and authority to do and perform each and every act
and thing requisite and necessary to be done in and about the premises, as fully to all
intents and purposes as he might or could do in person, hereby ratifying and confirming
all that said attorneys-in-fact and agents, or either of them, or their or his substitute
or substitutes, may lawfully do or cause to be done by virtue hereof.
[ADDITIONAL SIGNATURES
ON FOLLOWING PAGE]
II-5
Pursuant
to the requirements of the Securities Act of 1933, this Registration Statement on Form
S-8 was signed by the following persons in the capacities indicated on July 29, 2004.
SIGNATURE
TITLE
/s/ Dan R. Lee
Dan R. Lee
President, Chief Executive Officer and Director
(principal
executive officer)
/s/ Kenneth F. Davis
Kenneth F. Davis
Director
/s/ Michael E. Glasscock, III
Michael E. Glasscock, III
Director
/s/ Rosdon Hendrix
Rosdon Hendrix
Director
/s/ Gene R. McGrevin
Gene R. McGrevin
Director
/s/ Ronald L. Smorada
Ronald L. Smorada
Director
/s/ Roger G. Wilson
Roger G. Wilson
Chief Financial Officer, Treasurer and Assistant Secretary
(principal financial and accounting officer)
II-6
EXHIBIT INDEX
Exhibit No.
Description
5*
Opinion of counsel as to legality of the securities being registered
10(a)*
1999 Long-Term Incentive Plan, as amended May 19, 2004
23(a)
Consent of Arnall Golden  Gregory,  LLP (included in opinion filed as Exhibit 5)
23(b)*
Consent of KPMG LLP
23(c)*
Consent of Deloitte & Touche LLP
24
Power of Attorney (included on page II-5)
_________________
* Filed herewith.
II-7