<PAGE>
 
   As filed with the Securities and Exchange Commission on March 13, 1997

                                                 REGISTRATION NO. 333 -
 
===============================================================================

                      SECURITIES AND EXCHANGE COMMISSION
                            WASHINGTON, D.C. 20549

                               ---------------- 

                                   FORM S-8
                            REGISTRATION STATEMENT
                                   UNDER THE
                            SECURITIES ACT OF 1933

                               ---------------- 

                             MYRIAD GENETICS, INC.
            (Exact name of Registrant as specified in its charter)

           Delaware                                    87-0494517
(State or other jurisdiction                       (I.R.S. Employer
of incorporation or organization)                 Identification No.)

                                320 WAKARA WAY
                          SALT LAKE CITY, UTAH 84108
                                (801) 584-3600
                   (Address of Principal Executive Offices)

                    1992 EMPLOYEE, DIRECTOR AND CONSULTANT
                               STOCK OPTION PLAN
                           (Full titles of the plan)

                               PETER D. MELDRUM
                     PRESIDENT AND CHIEF EXECUTIVE OFFICER
                             MYRIAD GENETICS, INC.
                                320 WAKARA WAY
                          SALT LAKE CITY, UTAH 84108
                                (801) 584-3600
   (Name, address, including zip code, and telephone number, including area
                          code, of agent for service)

                               ---------------- 

                        CALCULATION OF REGISTRATION FEE

<TABLE>
<CAPTION>
=============================================================================================================
                                                      Proposed          Proposed
                                                      maximum           maximum
         Title of                  Amount to be    offering price       aggregate           Amount of
securities to be registered       registered/1/     per share/2/    offering price/2/   registration fee
-------------------------------------------------------------------------------------------------------------
<S>                               <C>              <C>             <C>                  <C>
Common Stock, $.01 par value            500,000          $36.00         $18,000,000            $5,455
=============================================================================================================
</TABLE>

(1) The number of shares of common stock, par value $.01 per share ("Common
    Stock"), stated above consists of the aggregate number of shares which may
    be sold upon the exercise of options which have been granted and/or may
    hereafter be granted under the Myriad Genetics, Inc. 1992 Employee, Director
    and Consultant Stock Option Plan (the "Plan").  The maximum number of shares
    which may be sold upon the exercise of such options granted under the Plan
    is subject to adjustment in accordance with certain anti-dilution and other
    provisions of the Plan.  Accordingly, pursuant to Rule 416 under the
    Securities Act of 1933, as amended (the "Securities Act"), this Registration
    Statement covers, in addition to the number of shares stated above, an
    indeterminate number of shares which may be subject to grant or otherwise
    issuable after the operation of any such anti-dilution and other provisions.

(2) This calculation is made solely for the purpose of determining the
    registration fee pursuant to the provisions of Rule 457(h) under the
    Securities Act.  The registration fee is calculated on the basis of the
    average of the high and low sale prices per share of the Common Stock on the
    National Market System of the National Association of Securities Dealers
    Automated Quotation System (Nasdaq) as of a date (March 7, 1997) within
    5 business days prior to filing this Registration Statement.

=============================================================================== 
<PAGE>
 
                                        EXPLANATORY NOTE
                                        ----------------


            In accordance with the instructional Note to Part I of Form S-8 as
       promulgated by the Securities and Exchange Commission (the "Commission"),
       the information specified by Part I of Form S-8 has been omitted from
       this Registration Statement on Form S-8 for offers of Common Stock
       pursuant to the Plan.  This Registration Statement on Form S-8 hereby
       registers 500,000 new shares of Common Stock pursuant to the Plan.  A
       Registration Statement on Form S-8 (File No. 333-04700), registering an
       aggregate of 1,000,000 shares of Common Stock under the Plan was filed
       with the Commission on May 3, 1996.
<PAGE>
 
                                    PART II

              INFORMATION REQUIRED IN THE REGISTRATION STATEMENT


Item 3.  Incorporation of Certain Documents by Reference.
-------------------------------------------------------- 

     The following documents filed by the Company with the Commission are
incorporated herein by reference:

     (a) The Company's Annual Report on Form 10-K for the fiscal year
         ended June 30, 1996.

     (b) The Company's Quarterly Report on Form 10-Q for the quarter
         ended September 30, 1996.

     (c) The Company's Quarterly Report on Form 10-Q for the quarter
         ended December 31, 1996.

     (d) The description of the Common Stock contained in the Company's
         Registration Statement on Form 8-A (File No. 0-26642) filed
         under the Securities Exchange Act of 1934, including any
         amendment or report filed for the purpose of updating such
         description.

      All reports and other documents filed by the Company after the date hereof
pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Securities Exchange Act
of 1934 prior to the filing of a post-effective amendment which indicates that
all securities offered hereby have been sold or which deregisters all securities
then remaining unsold, shall be deemed to be incorporated by reference herein
and to be part hereof from the date of filing of such reports and documents.

Item 4.  Description of Securities.
---------------------------------- 

     Not applicable.

Item 5.  Interests of Named Experts and Counsel.
----------------------------------------------- 

     The validity of the issuance of the shares of Common Stock
registered under this Registration Statement has been passed upon for the
Company by Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C. of Boston,
Massachusetts.  Members of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo,
P.C. own an aggregate of approximately 2,000 shares of Common Stock of
the Company.

Item 6.  Indemnification of Directors and Officers.
-------------------------------------------------- 

     Incorporated herein by reference to the Company's Registration
Statement on Form S-1, as amended, File No. 33-95970.

Item 7.  Exemption from Registration Claimed.
-------------------------------------------- 

     Not applicable.

Item 8.  Exhibits.
----------------- 

     (4.1)  Form of Common Stock Certificate (filed as Exhibit 4.2 to the
            Company's Registration Statement on Form S-1, as amended, File
            No. 33-95970, and incorporated herein by reference).

     (4.2)  Restated Certificate of Incorporation (filed as Exhibit 3.2
            to the Company's Registration Statement on Form S-1, as
            amended, File No. 33-95970, and incorporated herein by
            reference).

                                      II-1
<PAGE>
 
     (4.3)  Restated By-Laws (filed as Exhibit 3.4 to the Company's
            Registration Statement on Form S-1, as amended, File No. 33-
            95970, and incorporated herein by reference).

     (5)    Opinion of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
            as to the legality of the shares being registered.

     (10.1) 1992 Employee, Director and Consultant Stock Option Plan
            (filed as Exhibit 10.2 to the Company's Quarterly Report on
            Form 10-Q for the quarter ended December 31, 1996, and
            incorporated herein by reference).

     (23.1) Consent of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo,
            P.C. (included in opinion of counsel filed as Exhibit 5).

     (23.2) Consent of KPMG Peat Marwick LLP.

     (24)   Power of Attorney to file future amendments (set forth on the
            signature page of this Registration Statement).

Item 9.  Undertakings.
--------------------- 

(a)  The undersigned registrant hereby undertakes:

     (1)  To file, during any period in which offers or sales are being
          made, a post-effective amendment to this Registration
          Statement:

          (i)  To include any prospectus required by Section 10(a)(3) of 
               the Securities Act of 1933;

          (ii) To reflect in the prospectus any facts or events
               arising after the effective date of the Registration
               Statement (or the most recent post-effective
               amendment thereof) which, individually or in the
               aggregate, represents a fundamental change in the
               information set forth in the Registration Statement;

          (iii)  To include any material information with respect to
                 the plan of distribution not previously disclosed in
                 the Registration Statement or any material change to
                 such information in the Registration Statement;

            Provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii) do not
       apply if the Registration Statement is on Form S-3 or Form S-8, and the
       information required to be included in a post-effective amendment by
       those paragraphs is contained in periodic reports filed by the Company
       pursuant to Section 13 or Section 15(d) of the Securities Exchange Act of
       1934 that are incorporated by reference in this Registration Statement.

       (2)  That, for the purpose of determining any liability under the
            Securities Act of 1933, each such post-effective amendment
            shall be deemed to be a new registration statement relating to
            the securities offered therein, and the offering of such
            securities at that time shall be deemed to be the initial bona
            fide offering thereof.

       (3)  To remove from registration by means of a post-effective
            amendment any of the securities being registered which remain
            unsold at the termination of the offering.

                                      II-2
<PAGE>
 
(b)  The undersigned registrant hereby undertakes that, for purposes of
     determining any liability under the Securities Act of 1933, each filing of
     the Company's annual report pursuant to Section 13(a) or Section 15(d) of
     the Securities Exchange Act of 1934 that is incorporated by reference in
     this Registration Statement shall be deemed to be a new registration
     statement relating to the securities offered therein, and the offering of
     such securities at that time shall be deemed to be the initial bona fide
     offering thereof.

(c)  Insofar as indemnification for liabilities arising under the Securities Act
     of 1933 may be permitted to directors, officers and controlling persons of
     the Company pursuant to the foregoing provisions, or otherwise, the Company
     has been advised that in the opinion of the Securities and Exchange
     Commission such indemnification is against public policy as expressed in
     the Act and is, therefore, unenforceable. In the event that a claim for
     indemnification against such liabilities (other than the payment by the
     Company of expenses incurred or paid by a director, officer or controlling
     person of the Company in the successful defense of any action, suit or
     proceeding) is asserted by such director, officer or controlling person in
     connection with the securities being registered, the Company will, unless
     in the opinion of its counsel the matter has been settled by controlling
     precedent, submit to a court of appropriate jurisdiction the question
     whether such indemnification by it is against public policy as expressed in
     the Act and will be governed by the final adjudication of such issue.

                                      II-3
<PAGE>
 
                                  SIGNATURES

     The Registrant. Pursuant to the requirements of the Securities Act of 1933,
the Company certifies that it has reasonable grounds to believe that it meets
all of the requirements for filing on Form S-8 and has duly caused this
Registration Statement to be signed on its behalf by the undersigned, thereunto
duly authorized, in Salt Lake City, Utah on February 13, 1997.


                                    MYRIAD GENETICS, INC.



                                    By:   /s/ PETER D. MELDRUM
                                       --------------------------------
                                       Peter D. Meldrum
                                       President and Chief Executive Officer


     Each person whose signature appears below constitutes and appoints
Peter D. Meldrum and Jay M. Moyes, and each of them, his true and lawful
attorneys-in-fact and agents, with full power of substitution and
resubstitution in each of them, for him and in his name, place and stead,
and in any and all capacities, to sign any and all amendments (including
post-effective amendments) to this Registration Statement on Form S-8 of
Myriad Genetics, Inc., and to file the same, with all exhibits thereto
and other documents in connection therewith, with the Securities and
Exchange Commission, granting unto said attorneys-in-fact and agents, and
each of them, full power and authority to do and perform each and every
act and thing requisite or necessary to be done in or about the premises,
as full to all intents and purposes as he might or could do in person,
hereby ratifying and confirming all that said attorneys-in-fact and
agents or any of them or their or his substitute or substitutes may
lawfully do or cause to be done by virtue hereof.

     Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement  has been signed by the following persons in the
capacities and on the dates indicated.

     Signature                     Title                  Date
     ---------                     -----                  ----



/s/ JOHN J. HORAN           Chairman of the Board         February 13, 1997
-------------------------
John J. Horan



                            Vice Chairman of the Board    February   , 1997
-------------------------
Walter Gilbert, Ph.D.



/s/ PETER D. MELDRUM        President, Chief Executive    February 13, 1997
-------------------------   Officer and Director
Peter D. Meldrum            (principal executive officer)

                                      II-4
<PAGE>
 
/s/ MARK H. SKOLNICK, PH.D.      Executive Vice President      February 13, 1997
-------------------------------  of Research and Development 
Mark H. Skolnick, Ph.D.          and Director



/s/ JAY M. MOYES                 Vice President of Finance,    February 13, 1997
-------------------------------  Assistant Secretary and
Jay M. Moyes                     Assistant Treasurer
                                 (principal financial and
                                 accounting officer)



/s/ MICHAEL J. BERENDT, PH.D.    Director                      February 13, 1997
-------------------------------
Michael J. Berendt, Ph.D.



/s/ ARTHUR H. HAYES, JR., M.D.   Director                      February 13, 1997
-------------------------------
Arthur H. Hayes, Jr., M.D.



                                 Director                      February   , 1997
-------------------------------
Alan J. Main, Ph.D.



/s/ DALE A. STRINGFELLOW, PH.D.  Director                      February 13, 1997
-------------------------------                                   
Dale A. Stringfellow, Ph.D.

                                      II-5
<PAGE>
 
                             MYRIAD GENETICS, INC.

                         INDEX TO EXHIBITS FILED WITH
                        FORM S-8 REGISTRATION STATEMENT
<TABLE>
<CAPTION>
 
Exhibit                                                      Sequential
Number                         Description                    Page No.
-------                        -----------                    -------- 
<S>                <C>                                      <C>
 
  (4.1)            Form of Common Stock Certificate
                   (filed as Exhibit 4.2 to the Company's
                   Registration Statement on Form S-1, as
                   amended, File No. 33-95970, and
                   incorporated herein by reference).

  (4.2)            Restated Certificate of Incorporation
                   (filed as Exhibit 3.2 to the Company's
                   Registration Statement on Form S-1, as
                   amended, File No. 33-95970, and
                   incorporated herein by reference).

  (4.3)            Restated By-Laws (filed as Exhibit 3.4
                   to the Company's Registration
                   Statement on Form S-1, as amended,
                   File No. 33-95970, and incorporated
                   herein by reference).

  (5)              Opinion of Mintz, Levin, Cohn, Ferris,
                   Glovsky and Popeo, P.C. as to the
                   legality of the shares being
                   registered.

  (10.1)           1992 Employee, Director and Consultant
                   Stock Option Plan (filed as Exhibit
                   10.2 to the Company's Quarterly Report
                   on Form 10-Q for the quarter ended
                   December 31, 1996, and incorporated
                   herein by reference).

  (23.1)           Consent of Mintz, Levin, Cohn, Ferris,
                   Glovsky and Popeo, P.C. (included in
                   opinion of counsel filed as Exhibit 5).

  (23.2)           Consent of KPMG Peat Marwick LLP.

  (24)             Power of Attorney to file future
                   amendments (set forth on the signature
                   page of this Registration Statement).
 
</TABLE>

                                      II-6
[{"type": "S-8", "sequence": "1", "description": "FORM S-8", "secsgml_size_bytes": 18853}]
{"company-data": {"conformed-name": "MYRIAD GENETICS INC", "cik": "0000899923", "assigned-sic": "8731", "irs-number": "870494517", "state-of-incorporation": "DE", "fiscal-year-end": "0630"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-23255", "film-number": "97556016"}, "business-address": {"street1": "390 WAKARA WAY", "city": "SALT LAKE CITY", "state": "UT", "zip": "84108"}, "mail-address": {"street1": "390 WAKARA WAY", "city": "SALT LAKE CITY", "state": "UT", "zip": "84108"}}
As filed with the Securities and Exchange Commission on March 13, 1997

                                                 REGISTRATION NO. 333 -
 
===============================================================================

                      SECURITIES AND EXCHANGE COMMISSION
                            WASHINGTON, D.C. 20549

                               ---------------- 

                                   FORM S-8
                            REGISTRATION STATEMENT
                                   UNDER THE
                            SECURITIES ACT OF 1933

                               ---------------- 

                             MYRIAD GENETICS, INC.
            (Exact name of Registrant as specified in its charter)

           Delaware                                    87-0494517
(State or other jurisdiction                       (I.R.S. Employer
of incorporation or organization)                 Identification No.)

                                320 WAKARA WAY
                          SALT LAKE CITY, UTAH 84108
                                (801) 584-3600
                   (Address of Principal Executive Offices)

                    1992 EMPLOYEE, DIRECTOR AND CONSULTANT
                               STOCK OPTION PLAN
                           (Full titles of the plan)

                               PETER D. MELDRUM
                     PRESIDENT AND CHIEF EXECUTIVE OFFICER
                             MYRIAD GENETICS, INC.
                                320 WAKARA WAY
                          SALT LAKE CITY, UTAH 84108
                                (801) 584-3600
   (Name, address, including zip code, and telephone number, including area
                          code, of agent for service)

                               ---------------- 

                        CALCULATION OF REGISTRATION FEE
=============================================================================================================
                                                      Proposed          Proposed
                                                      maximum           maximum
         Title of                  Amount to be    offering price       aggregate           Amount of
securities to be registered       registered/1/     per share/2/    offering price/2/   registration fee
-------------------------------------------------------------------------------------------------------------
Common Stock, $.01 par value            500,000          $36.00         $18,000,000            $5,455
=============================================================================================================
(1) The number of shares of common stock, par value $.01 per share ("Common
    Stock"), stated above consists of the aggregate number of shares which may
    be sold upon the exercise of options which have been granted and/or may
    hereafter be granted under the Myriad Genetics, Inc. 1992 Employee, Director
    and Consultant Stock Option Plan (the "Plan").  The maximum number of shares
    which may be sold upon the exercise of such options granted under the Plan
    is subject to adjustment in accordance with certain anti-dilution and other
    provisions of the Plan.  Accordingly, pursuant to Rule 416 under the
    Securities Act of 1933, as amended (the "Securities Act"), this Registration
    Statement covers, in addition to the number of shares stated above, an
    indeterminate number of shares which may be subject to grant or otherwise
    issuable after the operation of any such anti-dilution and other provisions.

(2) This calculation is made solely for the purpose of determining the
    registration fee pursuant to the provisions of Rule 457(h) under the
    Securities Act.  The registration fee is calculated on the basis of the
    average of the high and low sale prices per share of the Common Stock on the
    National Market System of the National Association of Securities Dealers
    Automated Quotation System (Nasdaq) as of a date (March 7, 1997) within
    5 business days prior to filing this Registration Statement.

===============================================================================
EXPLANATORY NOTE
                                        ----------------

            In accordance with the instructional Note to Part I of Form S-8 as
       promulgated by the Securities and Exchange Commission (the "Commission"),
       the information specified by Part I of Form S-8 has been omitted from
       this Registration Statement on Form S-8 for offers of Common Stock
       pursuant to the Plan.  This Registration Statement on Form S-8 hereby
       registers 500,000 new shares of Common Stock pursuant to the Plan.  A
       Registration Statement on Form S-8 (File No. 333-04700), registering an
       aggregate of 1,000,000 shares of Common Stock under the Plan was filed
       with the Commission on May 3, 1996.
PART II

              INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

Item 3.  Incorporation of Certain Documents by Reference.
-------------------------------------------------------- 

     The following documents filed by the Company with the Commission are
incorporated herein by reference:

     (a) The Company's Annual Report on Form 10-K for the fiscal year
         ended June 30, 1996.

     (b) The Company's Quarterly Report on Form 10-Q for the quarter
         ended September 30, 1996.

     (c) The Company's Quarterly Report on Form 10-Q for the quarter
         ended December 31, 1996.

     (d) The description of the Common Stock contained in the Company's
         Registration Statement on Form 8-A (File No. 0-26642) filed
         under the Securities Exchange Act of 1934, including any
         amendment or report filed for the purpose of updating such
         description.

      All reports and other documents filed by the Company after the date hereof
pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Securities Exchange Act
of 1934 prior to the filing of a post-effective amendment which indicates that
all securities offered hereby have been sold or which deregisters all securities
then remaining unsold, shall be deemed to be incorporated by reference herein
and to be part hereof from the date of filing of such reports and documents.

Item 4.  Description of Securities.
---------------------------------- 

     Not applicable.

Item 5.  Interests of Named Experts and Counsel.
----------------------------------------------- 

     The validity of the issuance of the shares of Common Stock
registered under this Registration Statement has been passed upon for the
Company by Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C. of Boston,
Massachusetts.  Members of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo,
P.C. own an aggregate of approximately 2,000 shares of Common Stock of
the Company.

Item 6.  Indemnification of Directors and Officers.
-------------------------------------------------- 

     Incorporated herein by reference to the Company's Registration
Statement on Form S-1, as amended, File No. 33-95970.

Item 7.  Exemption from Registration Claimed.
-------------------------------------------- 

     Not applicable.

Item 8.  Exhibits.
----------------- 

     (4.1)  Form of Common Stock Certificate (filed as Exhibit 4.2 to the
            Company's Registration Statement on Form S-1, as amended, File
            No. 33-95970, and incorporated herein by reference).

     (4.2)  Restated Certificate of Incorporation (filed as Exhibit 3.2
            to the Company's Registration Statement on Form S-1, as
            amended, File No. 33-95970, and incorporated herein by
            reference).

                                      II-1
(4.3)  Restated By-Laws (filed as Exhibit 3.4 to the Company's
            Registration Statement on Form S-1, as amended, File No. 33-
            95970, and incorporated herein by reference).

     (5)    Opinion of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
            as to the legality of the shares being registered.

     (10.1) 1992 Employee, Director and Consultant Stock Option Plan
            (filed as Exhibit 10.2 to the Company's Quarterly Report on
            Form 10-Q for the quarter ended December 31, 1996, and
            incorporated herein by reference).

     (23.1) Consent of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo,
            P.C. (included in opinion of counsel filed as Exhibit 5).

     (23.2) Consent of KPMG Peat Marwick LLP.

     (24)   Power of Attorney to file future amendments (set forth on the
            signature page of this Registration Statement).

Item 9.  Undertakings.
--------------------- 

(a)  The undersigned registrant hereby undertakes:

     (1)  To file, during any period in which offers or sales are being
          made, a post-effective amendment to this Registration
          Statement:

          (i)  To include any prospectus required by Section 10(a)(3) of 
               the Securities Act of 1933;

          (ii) To reflect in the prospectus any facts or events
               arising after the effective date of the Registration
               Statement (or the most recent post-effective
               amendment thereof) which, individually or in the
               aggregate, represents a fundamental change in the
               information set forth in the Registration Statement;

          (iii)  To include any material information with respect to
                 the plan of distribution not previously disclosed in
                 the Registration Statement or any material change to
                 such information in the Registration Statement;

            Provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii) do not
       apply if the Registration Statement is on Form S-3 or Form S-8, and the
       information required to be included in a post-effective amendment by
       those paragraphs is contained in periodic reports filed by the Company
       pursuant to Section 13 or Section 15(d) of the Securities Exchange Act of
       1934 that are incorporated by reference in this Registration Statement.

       (2)  That, for the purpose of determining any liability under the
            Securities Act of 1933, each such post-effective amendment
            shall be deemed to be a new registration statement relating to
            the securities offered therein, and the offering of such
            securities at that time shall be deemed to be the initial bona
            fide offering thereof.

       (3)  To remove from registration by means of a post-effective
            amendment any of the securities being registered which remain
            unsold at the termination of the offering.

                                      II-2
(b)  The undersigned registrant hereby undertakes that, for purposes of
     determining any liability under the Securities Act of 1933, each filing of
     the Company's annual report pursuant to Section 13(a) or Section 15(d) of
     the Securities Exchange Act of 1934 that is incorporated by reference in
     this Registration Statement shall be deemed to be a new registration
     statement relating to the securities offered therein, and the offering of
     such securities at that time shall be deemed to be the initial bona fide
     offering thereof.

(c)  Insofar as indemnification for liabilities arising under the Securities Act
     of 1933 may be permitted to directors, officers and controlling persons of
     the Company pursuant to the foregoing provisions, or otherwise, the Company
     has been advised that in the opinion of the Securities and Exchange
     Commission such indemnification is against public policy as expressed in
     the Act and is, therefore, unenforceable. In the event that a claim for
     indemnification against such liabilities (other than the payment by the
     Company of expenses incurred or paid by a director, officer or controlling
     person of the Company in the successful defense of any action, suit or
     proceeding) is asserted by such director, officer or controlling person in
     connection with the securities being registered, the Company will, unless
     in the opinion of its counsel the matter has been settled by controlling
     precedent, submit to a court of appropriate jurisdiction the question
     whether such indemnification by it is against public policy as expressed in
     the Act and will be governed by the final adjudication of such issue.

                                      II-3
SIGNATURES

     The Registrant. Pursuant to the requirements of the Securities Act of 1933,
the Company certifies that it has reasonable grounds to believe that it meets
all of the requirements for filing on Form S-8 and has duly caused this
Registration Statement to be signed on its behalf by the undersigned, thereunto
duly authorized, in Salt Lake City, Utah on February 13, 1997.

                                    MYRIAD GENETICS, INC.

                                    By:   /s/ PETER D. MELDRUM
                                       --------------------------------
                                       Peter D. Meldrum
                                       President and Chief Executive Officer

     Each person whose signature appears below constitutes and appoints
Peter D. Meldrum and Jay M. Moyes, and each of them, his true and lawful
attorneys-in-fact and agents, with full power of substitution and
resubstitution in each of them, for him and in his name, place and stead,
and in any and all capacities, to sign any and all amendments (including
post-effective amendments) to this Registration Statement on Form S-8 of
Myriad Genetics, Inc., and to file the same, with all exhibits thereto
and other documents in connection therewith, with the Securities and
Exchange Commission, granting unto said attorneys-in-fact and agents, and
each of them, full power and authority to do and perform each and every
act and thing requisite or necessary to be done in or about the premises,
as full to all intents and purposes as he might or could do in person,
hereby ratifying and confirming all that said attorneys-in-fact and
agents or any of them or their or his substitute or substitutes may
lawfully do or cause to be done by virtue hereof.

     Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement  has been signed by the following persons in the
capacities and on the dates indicated.

     Signature                     Title                  Date
     ---------                     -----                  ----

/s/ JOHN J. HORAN           Chairman of the Board         February 13, 1997
-------------------------
John J. Horan

                            Vice Chairman of the Board    February   , 1997
-------------------------
Walter Gilbert, Ph.D.

/s/ PETER D. MELDRUM        President, Chief Executive    February 13, 1997
-------------------------   Officer and Director
Peter D. Meldrum            (principal executive officer)

                                      II-4
/s/ MARK H. SKOLNICK, PH.D.      Executive Vice President      February 13, 1997
-------------------------------  of Research and Development 
Mark H. Skolnick, Ph.D.          and Director

/s/ JAY M. MOYES                 Vice President of Finance,    February 13, 1997
-------------------------------  Assistant Secretary and
Jay M. Moyes                     Assistant Treasurer
                                 (principal financial and
                                 accounting officer)

/s/ MICHAEL J. BERENDT, PH.D.    Director                      February 13, 1997
-------------------------------
Michael J. Berendt, Ph.D.

/s/ ARTHUR H. HAYES, JR., M.D.   Director                      February 13, 1997
-------------------------------
Arthur H. Hayes, Jr., M.D.

                                 Director                      February   , 1997
-------------------------------
Alan J. Main, Ph.D.

/s/ DALE A. STRINGFELLOW, PH.D.  Director                      February 13, 1997
-------------------------------                                   
Dale A. Stringfellow, Ph.D.

                                      II-5
MYRIAD GENETICS, INC.

                         INDEX TO EXHIBITS FILED WITH
                        FORM S-8 REGISTRATION STATEMENT
Exhibit                                                      Sequential
Number                         Description                    Page No.
-------                        -----------                    --------
(4.1)            Form of Common Stock Certificate
                   (filed as Exhibit 4.2 to the Company's
                   Registration Statement on Form S-1, as
                   amended, File No. 33-95970, and
                   incorporated herein by reference).

  (4.2)            Restated Certificate of Incorporation
                   (filed as Exhibit 3.2 to the Company's
                   Registration Statement on Form S-1, as
                   amended, File No. 33-95970, and
                   incorporated herein by reference).

  (4.3)            Restated By-Laws (filed as Exhibit 3.4
                   to the Company's Registration
                   Statement on Form S-1, as amended,
                   File No. 33-95970, and incorporated
                   herein by reference).

  (5)              Opinion of Mintz, Levin, Cohn, Ferris,
                   Glovsky and Popeo, P.C. as to the
                   legality of the shares being
                   registered.

  (10.1)           1992 Employee, Director and Consultant
                   Stock Option Plan (filed as Exhibit
                   10.2 to the Company's Quarterly Report
                   on Form 10-Q for the quarter ended
                   December 31, 1996, and incorporated
                   herein by reference).

  (23.1)           Consent of Mintz, Levin, Cohn, Ferris,
                   Glovsky and Popeo, P.C. (included in
                   opinion of counsel filed as Exhibit 5).

  (23.2)           Consent of KPMG Peat Marwick LLP.

  (24)             Power of Attorney to file future
                   amendments (set forth on the signature
                   page of this Registration Statement).
II-6