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<P style="margin-top:0pt; margin-bottom:2.5pt; padding-bottom:3pt; font-family:Palatino Linotype; border-bottom:3pt double #000000" align=center>As filed with the Securities and Exchange Commission on May&nbsp;19,&nbsp;2008</P>
<P style="margin-top:0pt; margin-bottom:5pt; padding-bottom:3pt; text-indent:14.4pt; font-family:Palatino Linotype; border-bottom:3pt double #000000" align=right>Commission File No.&nbsp;_______ </P>
<P style="margin-top:3.5pt; margin-bottom:3.5pt; line-height:16pt; font-family:Palatino Linotype; font-size:14pt" align=center><B>SECURITIES AND EXCHANGE COMMISSION</B></P>
<P style="margin-top:0pt; margin-bottom:2.9pt; font-family:Palatino Linotype; font-size:12pt" align=center><B>WASHINGTON, D.C.&nbsp;20549<BR>
_________________</B></P>
<P style="margin-top:0pt; margin-bottom:4pt; line-height:18pt; font-family:Palatino Linotype; font-size:16pt" align=center><B><BR>
Form S-8</B></P>
<P style="margin:0pt; line-height:14pt; font-family:Palatino Linotype; font-size:12pt" align=center><B>Registration Statement Under The Securities Act Of&nbsp;1933</B></P>
<P style="margin-top:0pt; margin-bottom:5.75pt; text-indent:14.4pt; line-height:13.5pt; font-family:Palatino Linotype; font-size:11.5pt" align=center><B><U>&nbsp;&nbsp;&nbsp;</U></B></P>
<P style="margin-top:0pt; margin-bottom:5pt; line-height:22pt; font-family:Palatino Linotype; font-size:20pt" align=center><B>Signalife, Inc.</B></P>
<P style="margin:0pt; line-height:10pt; font-family:Palatino Linotype; font-size:8pt" align=center><B>(Exact name of registrant as specified in its charter)</B></P>
<P style="margin:0pt; font-family:Palatino Linotype" align=center><B><BR></B></P>
<TABLE style="font-size:10pt" cellspacing=0 align=center><TR><TD valign=top width=205.2><P style="margin-top:0pt; margin-bottom:2.5pt; font-family:Palatino Linotype" align=center><B>Delaware</B></P>
<P style="margin:0pt; line-height:10pt; font-family:Palatino Linotype; font-size:8pt" align=center><B>(State or other jurisdiction of</B></P>
<P style="margin:0pt; line-height:10pt; font-family:Palatino Linotype; font-size:8pt" align=center><B>incorporation or organization)</B></P>
</TD><TD valign=top width=234>&nbsp;</TD><TD valign=top width=199.2><P style="margin-top:0pt; margin-bottom:2.5pt; font-family:Palatino Linotype" align=center><B>87-0441351</B></P>
<P style="margin:0pt; line-height:10pt; font-family:Palatino Linotype; font-size:8pt" align=center><B>(I.R.S. Employer</B></P>
<P style="margin-top:0pt; margin-bottom:2.75pt; line-height:10pt; font-family:Palatino Linotype; font-size:8pt" align=center><B>Identification No.)</B></P>
</TD></TR>
</TABLE>
<P style="margin-top:0pt; margin-bottom:5pt; font-family:Palatino Linotype" align=center><B><BR></B></P>
<P style="margin-top:0pt; margin-bottom:2.5pt; padding-left:-18pt; padding-right:-20.15pt; font-family:Palatino Linotype" align=center><B>Common shares available and reserved for issuance under the Signalife, Inc.&nbsp;2006 Omnibus Equity Compensation Plan</B></P>
<P style="margin:0pt; padding-left:-18pt; padding-right:-19.8pt; font-family:Palatino Linotype; font-size:11pt" align=center><B>(<SMALL>Full title of plan(s))<BR>
</SMALL></B></P>
<P style="margin:0pt; padding-left:-18pt; padding-right:-19.8pt; font-family:Palatino Linotype" align=center><B><BR></B></P>
<P style="margin:0pt; font-family:Palatino Linotype" align=center><B>Rowland Perkins </B></P>
<P style="margin:0pt; font-family:Palatino Linotype" align=center><B>Interim Administrative Chief Executive Officer</B></P>
<P style="margin:0pt; font-family:Palatino Linotype" align=center><B>Signalife, Inc.</B></P>
<P style="margin:0pt; font-family:Palatino Linotype" align=center><B>531 South Main Street, Suite&nbsp;301</B></P>
<P style="margin:0pt; font-family:Palatino Linotype" align=center><B>Greenville, South Carolina&nbsp;29601</B></P>
<P style="margin-top:0pt; margin-bottom:2.5pt; font-family:Palatino Linotype" align=center><B>(864)&nbsp;233-2300</B></P>
<P style="margin:0pt; font-family:Palatino Linotype; font-size:11pt" align=center><B>(<SMALL>Name and address of agent for service of process)</SMALL></B></P>
<P style="margin-top:0pt; margin-bottom:5pt; line-height:10pt; font-family:Palatino Linotype; font-size:8pt" align=center><B>(Telephone number, including area code, of agent for service of process)</B></P>
<P style="margin-top:0pt; margin-bottom:5pt; font-family:Palatino Linotype" align=center>Copies to</P>
<P style="margin:0pt; font-family:Palatino Linotype" align=center><B>John M. Woodbury, Jr., Esq.</B></P>
<P style="margin:0pt; font-family:Palatino Linotype" align=center><B>7251 Owensmouth Ave, Suite 7</B></P>
<P style="margin:0pt; font-family:Palatino Linotype" align=center><B>Canoga Park, California &nbsp;91303</B></P>
<P style="margin-top:0pt; margin-bottom:8.35pt; font-family:Palatino Linotype" align=center><B>(818) 883-1767</B></P>
<P style="margin-top:0pt; margin-bottom:5pt; text-indent:13.5pt; font-family:Palatino Linotype" align=center><B>Calculation of Registration Fee</B></P>
<TABLE style="font-size:10pt" cellspacing=0 align=center><TR><TD style="border-bottom:1.5pt solid #000000" valign=top width=229.2><P style="margin:0pt; font-family:Palatino Linotype" align=center><B><BR>
<BR>
<BR>
Title of Securities to be Registered</B></P>
</TD><TD style="border-bottom:1.5pt solid #000000" valign=top width=108><P style="margin:0pt; text-indent:-0.9pt; font-family:Palatino Linotype" align=center><B><BR>
Amount <BR>
to be <BR>
Registered(1)</B></P>
</TD><TD style="border-bottom:1.5pt solid #000000" valign=top width=114><P style="margin:0pt; text-indent:-0.9pt; font-family:Palatino Linotype" align=center><B>Proposed <BR>
Maximum<BR>
Offering Price <BR>
Per Share</B></P>
</TD><TD style="border-bottom:1.5pt solid #000000" valign=top width=120><P style="margin:0pt; text-indent:-0.9pt; font-family:Palatino Linotype" align=center><B>Proposed <BR>
Maximum<BR>
Aggregate <BR>
Offering Price</B></P>
</TD><TD style="border-bottom:1.5pt solid #000000" valign=top width=108><P style="margin:0pt; text-indent:-0.9pt; font-family:Palatino Linotype" align=center><B><BR>
Amount <BR>
of <BR>
Registration Fee</B></P>
</TD></TR>
<TR><TD valign=top width=229.2><P style="margin-top:1.65pt; margin-bottom:1.65pt; padding-left:9.35pt; text-indent:-9.35pt; font-family:Palatino Linotype">Common stock </P>
</TD><TD valign=bottom width=108><P style="margin-top:1.65pt; margin-bottom:1.65pt; text-indent:-0.9pt; font-family:Palatino Linotype" align=right>5,657,334</P>
</TD><TD valign=bottom width=114><P style="margin-top:1.65pt; margin-bottom:1.65pt; text-indent:-0.9pt; font-family:Palatino Linotype" align=center>$ &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;0.38&nbsp;(2)</P>
</TD><TD valign=bottom width=120><P style="margin-top:1.65pt; margin-bottom:1.65pt; padding-right:5.4pt; text-indent:1.8pt; font-family:Palatino Linotype" align=right>$ &nbsp;&nbsp;&nbsp;&nbsp;2,149,786.92</P>
</TD><TD valign=bottom width=108><P style="margin-top:1.65pt; margin-bottom:1.65pt; padding-right:9.9pt; text-indent:6.3pt; font-family:Palatino Linotype" align=center>$ &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;84.49</P>
</TD></TR>
<TR><TD style="border-top:1pt solid #000000; border-bottom:1.5pt solid #000000" valign=top width=229.2><P style="margin-top:1.65pt; margin-bottom:1.65pt; padding-left:9pt; text-indent:18pt; font-family:Palatino Linotype">Total</P>
</TD><TD style="border-top:1pt solid #000000; border-bottom:1.5pt solid #000000" valign=top width=108><P style="margin-top:1.65pt; margin-bottom:1.65pt; text-indent:-0.9pt; font-family:Palatino Linotype" align=right>5,657,334</P>
</TD><TD style="border-top:1pt solid #000000; border-bottom:1.5pt solid #000000" valign=top width=114>&nbsp;</TD><TD style="border-top:1pt solid #000000; border-bottom:1.5pt solid #000000" valign=bottom width=120><P style="margin-top:1.65pt; margin-bottom:1.65pt; padding-right:5.4pt; text-indent:1.8pt; font-family:Palatino Linotype" align=right>$ &nbsp;&nbsp;&nbsp;&nbsp;2,149,786.92</P>
</TD><TD style="border-top:1pt solid #000000; border-bottom:1.5pt solid #000000" valign=bottom width=108><P style="margin-top:1.65pt; margin-bottom:1.65pt; padding-right:9.9pt; text-indent:6.3pt; font-family:Palatino Linotype" align=center>$ &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;84.49</P>
</TD></TR>
<TR><TD valign=top width=679.2 colspan=5><P style="margin-top:1.5pt; margin-bottom:-11pt; padding-left:36pt; text-indent:-18pt; line-height:11pt; font-family:Palatino Linotype; font-size:9pt">(1)</P>
<P style="margin:0pt; padding-left:36pt; line-height:11pt; font-family:Palatino Linotype; font-size:9pt">Pursuant to SEC Rule 416(a), also covers additional common shares that may be offered to prevent dilution as a result of stock splits, stock dividends or similar transactions relating to these shares.</P>
<P style="margin-top:1.5pt; margin-bottom:-11pt; padding-left:36pt; text-indent:-18pt; line-height:11pt; font-family:Palatino Linotype; font-size:9pt">(2)</P>
<P style="margin:0pt; padding-left:36pt; line-height:11pt; font-family:Palatino Linotype; font-size:9pt">Pursuant to Rule 457(h)(1) and 457(c), the filing fee is computed upon the basis of the average of the high and low prices reported by the American Stock Exchange as of the close of market on May 15, 2008.</P>
</TD></TR>
</TABLE>
<P style="margin-top:0pt; margin-bottom:8.35pt; font-family:Palatino Linotype"><BR></P>
<A NAME="_Toc415383776"></A><A NAME="_Toc415479463"></A><P style="margin-top:0pt; margin-bottom:8.35pt; font-family:Palatino Linotype"><BR>
<BR></P>
<HR style="padding-top:7.2pt; padding-bottom:7.2pt" noshade size=1.333>
<P style="page-break-before:always; margin-top:0pt; margin-bottom:5pt; font-family:Palatino Linotype" align=center><B>PART I</B></P>
<P style="margin-top:0pt; margin-bottom:8.35pt; font-family:Palatino Linotype" align=center><B>INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS</B></P>
<P style="margin-top:0pt; margin-bottom:-11.5pt; line-height:11.5pt; font-family:Palatino Linotype; font-size:9.5pt"><B>Items 1 and 2.</B></P>
<B><P style="margin-top:0pt; margin-bottom:7.9pt; text-indent:100.8pt; line-height:12.45pt; font-family:Palatino Linotype; font-size:9.5pt">Plan Information; Registrant Information And Employee Plan Annual Information</B></P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype">Not Applicable</P>
<P style="margin-top:0pt; margin-bottom:8.35pt; font-family:Palatino Linotype" align=center><B>PART II</B></P>
<P style="margin-top:0pt; margin-bottom:8.35pt; font-family:Palatino Linotype" align=center><B>INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</B></P>
<P style="margin-top:0pt; margin-bottom:-12pt; font-family:Palatino Linotype"><B>Item&nbsp;</B></P>
<P style="margin-top:0pt; margin-bottom:-12pt; text-indent:28.8pt; font-family:Palatino Linotype"><B>3</B></P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:67.2pt; line-height:13pt; font-family:Palatino Linotype"><B>Incorporation Of Documents By Reference</B></P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype">We incorporate by reference into this prospectus the documents listed below or excerpts therefrom, as the case may be, as well as all other documents we may file with the SEC pursuant to Sections&nbsp;13(a),&nbsp;13(c),&nbsp;14 and&nbsp;15(d) of the Exchange Act after the date of this registration statement and prior to the filing of a post-effective amendment to this registration statement which indicates that all common shares offered under this registration statement have been sold, or which deregisters all common shares offered under this registration statement then remaining unsold::</P>
<P style="margin-top:0pt; margin-bottom:-12pt; padding-left:36pt; text-indent:-36pt; font-family:Palatino Linotype">(1)</P>
<P style="margin-top:0pt; margin-bottom:8.35pt; padding-left:36pt; font-family:Palatino Linotype">our annual report on form&nbsp;10-KSB filed for our fiscal year ended December 31,&nbsp;2007, as filed with the Securities and Exchange Commission on April&nbsp;3,&nbsp;2008 pursuant to Section&nbsp;13(a) of the Exchange Act of&nbsp;1934, as it may be amended from time-to-time;</P>
<P style="margin-top:0pt; margin-bottom:-12pt; padding-left:36pt; text-indent:-36pt; font-family:Palatino Linotype">(2)</P>
<P style="margin-top:0pt; margin-bottom:8.35pt; padding-left:36pt; font-family:Palatino Linotype">all other reports we have filed pursuant to Section&nbsp;13(a) or&nbsp;15(d) of the Exchange Act since December 31,&nbsp;2007; and</P>
<P style="margin-top:0pt; margin-bottom:-12pt; padding-left:36pt; text-indent:-36pt; font-family:Palatino Linotype">(3)</P>
<P style="margin-top:0pt; margin-bottom:8.35pt; padding-left:36pt; font-family:Palatino Linotype">the description of our common shares contained in that section captioned &#147;<I>Description of Equity Securities&#151;Common Shares</I>&#148; contained in our registration statement on form SB-2 (SEC file no. 333&#151;148515) as filed with the Securities and Exchange Commission on January 8, 2008 and declared effective on January 16, 2008.</P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype">All documents we may file with the Securities and Exchange Commission pursuant to Sections&nbsp;13(a),&nbsp;13(c),&nbsp;14 and&nbsp;15(d) of the Exchange Act after the date of this registration statement and prior to the filing of a post-effective amendment to this registration statement which indicates that all common shares offered under this registration statement have been sold, or which deregisters all common shares offered under this registration statement then remaining unsold, shall be deemed to be incorporated by reference in the registration statement and to be a part hereof from the date of filing of such documents.</P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype">For purposes of this registration statement, any document or any statement contained in a document incorporated or deemed to be incorporated herein by reference shall be deemed to be modified or superseded to the extent that a subsequently filed document or a statement contained herein or in any other subsequently filed document which also is or is deemed to be incorporated herein by reference modifies or supersedes such document or such statement in such document. &nbsp;Any statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this registration statement.</P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype">Notwithstanding the above, information that is &quot;furnished to&quot; the SEC shall not be deemed &quot;filed with&quot; the SEC and shall not be deemed incorporated by reference into this registration statement.</P>
<P style="margin-top:0pt; margin-bottom:-11.5pt; line-height:11.5pt; font-family:Palatino Linotype; font-size:9.5pt"><B>Item 4.</B></P>
<B><P style="margin-top:0pt; margin-bottom:7.9pt; text-indent:67.2pt; line-height:12.45pt; font-family:Palatino Linotype; font-size:9.5pt">Description of Securities</B></P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype">Not applicable&#151;the common shares to be offered and sold under this prospectus are registered under Section 12(b) of the Securities Exchange Act of 1934.</P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype"><BR>
<BR></P>
<P style="margin:0pt; line-height:11pt; font-family:Palatino Linotype; font-size:9pt" align=center>-2-</P>
<P style="margin:0pt; text-indent:14.4pt; font-family:Palatino Linotype; font-size:9pt"><BR></P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype"><BR></P>
<HR style="padding-top:7.2pt; padding-bottom:7.2pt" noshade size=1.333>
<P style="page-break-before:always; margin-top:0pt; margin-bottom:-11.5pt; line-height:11.5pt; font-family:Palatino Linotype; font-size:9.5pt"><B>Item 5.</B></P>
<B><P style="margin-top:0pt; margin-bottom:7.9pt; text-indent:67.2pt; line-height:12.45pt; font-family:Palatino Linotype; font-size:9.5pt">Interests of Named Experts and Counsel</B></P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype">Not applicable.</P>
<P style="margin-top:0pt; margin-bottom:-11.5pt; line-height:11.5pt; font-family:Palatino Linotype; font-size:9.5pt"><B>Item&nbsp;6</B></P>
<B><P style="margin-top:0pt; margin-bottom:7.9pt; text-indent:67.2pt; line-height:12.45pt; font-family:Palatino Linotype; font-size:9.5pt">Indemnification Of Directors And Officers</B></P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype">Our Certificate of Incorporation provides shall that we shall, to the maximum extent and in the manner under Delaware corporate law, indemnify each of our directors and officers against judgments, fines, settlements and other amounts, including expenses such as attorneys&#146; fees, actually and reasonably incurred in connection with any proceeding, arising by reason of the fact that such person is or was an agent of the corporation. &nbsp;We may also have contractual indemnification obligations under our individual agreements with our directors, officers and employees.</P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype">The foregoing indemnification obligations could result in our company incurring substantial expenditures to cover the cost of settlement or damage awards against directors, officers and employees, which we may be unable to recoup. &nbsp;These provisions and resultant costs may also discourage our company from bringing a lawsuit against directors, officers and employees for breaches of their fiduciary duties, including breaches resulting from negligent or grossly negligent behavior, except under certain situations defined by statute, and may similarly discourage the filing of derivative litigation by our shareholders against our directors, officers and employees, even though such actions, if successful, might otherwise benefit our company and shareholders. &nbsp;We believe that the indemnification provisions in our Articles of Incorporation are necessary to attract and retain qualified persons as directors and officers.</P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype">Insofar as indemnification for liabilities arising under the Securities Act of&nbsp;1933 may be permitted to our directors, officers and controlling persons pursuant to the foregoing provisions, or otherwise, we have been advised that in the opinion of the SEC such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. &nbsp;In the event that a claim for indemnification against such liabilities, other than the payment by the registrant of expenses incurred or paid by a director, officer or controlling person of the registrant in the successful defense of any action, suit or proceeding, is asserted by such director, officer or controlling person in connection with the securities being registered, we will, unless in the opinion of our counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by us is against public policy as expressed in the Securities Act and we will be governed by the final adjudication of such issue.</P>
<P style="margin-top:0pt; margin-bottom:-11.5pt; line-height:11.5pt; font-family:Palatino Linotype; font-size:9.5pt"><B>Item&nbsp;7</B></P>
<B><P style="margin-top:0pt; margin-bottom:7.9pt; text-indent:67.2pt; line-height:12.45pt; font-family:Palatino Linotype; font-size:9.5pt">Exemption From Registration Claimed</B></P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype">Not applicable.</P>
<P style="margin-top:0pt; margin-bottom:-11.5pt; line-height:11.5pt; font-family:Palatino Linotype; font-size:9.5pt"><B>Item&nbsp;8</B></P>
<B><P style="margin-top:0pt; margin-bottom:7.9pt; text-indent:67.2pt; line-height:12.45pt; font-family:Palatino Linotype; font-size:9.5pt">Exhibits And Financial Statement Schedules</B></P>
<P style="margin-top:0pt; margin-bottom:-12pt; padding-left:36pt; text-indent:-36pt; font-family:Times New Roman">3.1</P>
<P style="margin-top:0pt; margin-bottom:5pt; padding-left:36pt; font-family:Times New Roman"><FONT FACE="Palatino Linotype">Restated Certificate Of Incorporation Of Signalife,&nbsp;Inc. filed by the Delaware Secretary of State on May 5,&nbsp;2006&nbsp;(1)</FONT></P>
<P style="margin-top:0pt; margin-bottom:-12pt; padding-left:36pt; text-indent:-36pt; font-family:Times New Roman">3.2</P>
<P style="margin-top:0pt; margin-bottom:5pt; padding-left:36pt; font-family:Times New Roman"><FONT FACE="Palatino Linotype">Restated Bylaws adopted as of May 5, 2006&nbsp;(1)</FONT></P>
<P style="margin-top:0pt; margin-bottom:-12pt; padding-left:36pt; text-indent:-36pt; font-family:Times New Roman">4</P>
<P style="margin-top:0pt; margin-bottom:5pt; padding-left:36pt; font-family:Times New Roman"><FONT FACE="Palatino Linotype">Signalife 2006 Omnibus Equity Compensation Plan, as adopted effective as of June 7, 2006&nbsp;(2)</FONT></P>
<P style="margin-top:0pt; margin-bottom:-12pt; padding-left:36pt; text-indent:-36pt; font-family:Palatino Linotype">5.</P>
<P style="margin-top:0pt; margin-bottom:5pt; padding-left:36pt; font-family:Palatino Linotype">Legal opinion by John M. Woodbury, Jr., Esq.&nbsp;*</P>
<P style="margin-top:0pt; margin-bottom:-12pt; padding-left:36pt; text-indent:-36pt; font-family:Palatino Linotype">23.1</P>
<P style="margin-top:0pt; margin-bottom:5pt; padding-left:36pt; font-family:Palatino Linotype">Consent of legal counsel (John M. Woodbury, Jr.)&nbsp;(3)</P>
<P style="margin-top:0pt; margin-bottom:-12pt; padding-left:36pt; text-indent:-36pt; font-family:Palatino Linotype">23.2</P>
<P style="margin-top:0pt; margin-bottom:5pt; padding-left:36pt; font-family:Palatino Linotype">Consent of Independent Registered Public Accounting Firm (Elliott Davis, LLC)&nbsp;*</P>
<P style="margin:0pt; padding-left:36pt; font-family:Palatino Linotype"><U><BR></U></P>
<P style="margin-top:2.5pt; margin-bottom:-12pt; padding-left:54pt; text-indent:-18pt; font-family:Palatino Linotype">*</P>
<P style="margin:0pt; padding-left:54pt; font-family:Palatino Linotype">Filed herewith</P>
<P style="margin-top:2.5pt; margin-bottom:-12pt; padding-left:36.15pt; text-indent:-21.75pt; font-family:Palatino Linotype">(1)</P>
<P style="margin:0pt; padding-left:36.15pt; font-family:Palatino Linotype">Previously filed as an exhibit to our current report on form&nbsp;8-K filed with the SEC on May&nbsp;11,&nbsp;2006.</P>
<P style="margin-top:2.5pt; margin-bottom:0pt; padding-left:36.15pt; text-indent:-21.75pt; font-family:Palatino Linotype"><BR>
<BR></P>
<P style="margin:0pt; line-height:11pt; font-family:Palatino Linotype; font-size:9pt" align=center>-3-</P>
<P style="margin:0pt; text-indent:14.4pt; font-family:Palatino Linotype; font-size:9pt"><BR></P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype"><BR></P>
<HR style="padding-top:7.2pt; padding-bottom:7.2pt" noshade size=1.333>
<P style="page-break-before:always; margin-top:2.5pt; margin-bottom:-12pt; padding-left:36.15pt; text-indent:-21.75pt; font-family:Palatino Linotype">(2)</P>
<P style="margin:0pt; padding-left:36.15pt; font-family:Palatino Linotype">Previously filed as an exhibit to our registration statement on form S-8 filed with the SEC on June&nbsp;12,&nbsp;2006.</P>
<P style="margin-top:2.5pt; margin-bottom:-12pt; padding-left:36.15pt; text-indent:-21.75pt; font-family:Palatino Linotype">(3)</P>
<P style="margin:0pt; padding-left:36.15pt; font-family:Palatino Linotype">Included in legal opinion filed as exhibit 5 *</P>
<P style="margin-top:2.5pt; margin-bottom:0pt; padding-left:-0.7pt; font-family:Palatino Linotype"><BR></P>
<P style="margin-top:0pt; margin-bottom:-11.5pt; line-height:11.5pt; font-family:Palatino Linotype; font-size:9.5pt"><B>Item&nbsp;9</B></P>
<B><P style="margin-top:0pt; margin-bottom:7.9pt; text-indent:67.2pt; line-height:12.45pt; font-family:Palatino Linotype; font-size:9.5pt">Undertakings</B></P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype">We hereby undertake to: </P>
<P style="margin-top:0pt; margin-bottom:-12pt; padding-left:18pt; text-indent:-18pt; font-family:Palatino Linotype">1.</P>
<P style="margin-top:0pt; margin-bottom:8.35pt; padding-left:18pt; font-family:Palatino Linotype">File, during any period in which we offer or sell securities, a post-effective amendment to this registration statement to: </P>
<P style="margin-top:0pt; margin-bottom:-12pt; padding-left:72pt; text-indent:-36pt; font-family:Palatino Linotype">(i)</P>
<P style="margin-top:0pt; margin-bottom:8.35pt; padding-left:72pt; text-indent:-9pt; font-family:Palatino Linotype">include any prospectus required by section&nbsp;10(a)(3) of the Securities Act (unless incorporated by reference in this registration statement from periodic reports filed by the issuer under the Exchange Act), </P>
<P style="margin-top:0pt; margin-bottom:-12pt; padding-left:72pt; text-indent:-36pt; font-family:Palatino Linotype">(ii)</P>
<P style="margin-top:0pt; margin-bottom:8.35pt; padding-left:72pt; text-indent:-9pt; font-family:Palatino Linotype">reflect in the prospectus any facts or events which, individually or together, represent a fundamental change in the information in the registration statement; and notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospects filed with the SEC under Rule&nbsp;424(b) if, in the aggregate, the changes in the volume and price represent no more than a&nbsp;20% change in the maximum aggregate offering price set forth in the &#147;Calculation of Registration Fee&#148; table on the face page of the effective registration statement (unless incorporated by reference in this registration statement from periodic reports filed by the issuer under the Exchange Act); or</P>
<P style="margin-top:0pt; margin-bottom:-12pt; padding-left:72pt; text-indent:-36pt; font-family:Palatino Linotype">(iii)</P>
<P style="margin-top:0pt; margin-bottom:8.35pt; padding-left:72pt; text-indent:-9pt; font-family:Palatino Linotype">include any additional or changed material information on the plan of distribution. </P>
<P style="margin-top:0pt; margin-bottom:-12pt; padding-left:18pt; text-indent:-18pt; font-family:Palatino Linotype">2.</P>
<P style="margin-top:0pt; margin-bottom:8.35pt; padding-left:18pt; font-family:Palatino Linotype">For determining liability under the Securities Act, treat each post-effective amendment as a new registration statement of the securities offered, and the offering of the securities at that time to be the initial bona fide offering. </P>
<P style="margin-top:0pt; margin-bottom:-12pt; padding-left:18pt; text-indent:-18pt; font-family:Palatino Linotype">3.</P>
<P style="margin-top:0pt; margin-bottom:8.35pt; padding-left:18pt; font-family:Palatino Linotype">File a post-effective amendment to remove from registration any of the securities that remain unsold at the end of the offering. </P>
<P style="margin-top:0pt; margin-bottom:-12pt; padding-left:18pt; text-indent:-18pt; font-family:Palatino Linotype">4.</P>
<P style="margin-top:0pt; margin-bottom:8.35pt; padding-left:18pt; font-family:Palatino Linotype">For determining any liability under the Securities Act, treat each post-effective amendment that contains a form of prospectus as a new registration statement for the securities offered in the registration statement, and that offering of the securities at that time as the initial bona fide offering of those securities. &nbsp;Insofar as indemnification for liabilities arising under the Securities Act may be permitted to our directors, officers and controlling persons under the foregoing provisions or otherwise, we have been advised that in the opinion of the SEC such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. &nbsp;If a claim for indemnification against such liabilities (other than our payment of expenses incurred or paid by any of our directors, officers or controlling persons in the successful defense of any action, suit, or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered, we will, unless in the opinion of our counsel the matter has been settled by a controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by us is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue. </P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype" align=center><B><BR>
<BR></B></P>
<P style="margin:0pt; line-height:11pt; font-family:Palatino Linotype; font-size:9pt" align=center>-4-</P>
<P style="margin:0pt; text-indent:14.4pt; font-family:Palatino Linotype; font-size:9pt"><BR></P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype"><BR></P>
<HR style="padding-top:7.2pt; padding-bottom:7.2pt" noshade size=1.333>
<P style="page-break-before:always; margin-top:0pt; margin-bottom:8.35pt; font-family:Palatino Linotype" align=center><B>SIGNATURES</B></P>
<P style="margin-top:0pt; margin-bottom:8.35pt; font-family:Palatino Linotype">Pursuant to the requirements of the Securities Act of&nbsp;1933, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements of filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Greenville, State of South Carolina, on May&nbsp;16&nbsp;2008.</P>
<TABLE style="font-size:10pt" cellspacing=0 align=center><TR><TD valign=top width=301.2>&nbsp;</TD><TD valign=top width=342 colspan=2><P style="margin-top:0pt; margin-bottom:15pt; font-family:Palatino Linotype"><B>SIGNALIFE, INC.</B></P>
</TD></TR>
<TR><TD valign=top width=301.2>&nbsp;</TD><TD valign=top width=36><P style="margin:0pt; font-family:Palatino Linotype">By:</P>
</TD><TD style="border-bottom:0.5pt solid #000000" valign=top width=306>&nbsp;</TD></TR>
<TR><TD valign=top width=301.2>&nbsp;</TD><TD valign=top width=342 colspan=2><P style="margin-top:0pt; margin-bottom:8.35pt; padding-left:21.6pt; font-family:Palatino Linotype">Rowland Perkins<BR>
Interim Administrative Chief Executive Officer <BR>
(co-principal executive officer)</P>
</TD></TR>
<TR><TD valign=top width=301.2>&nbsp;</TD><TD valign=top width=36><P style="margin:0pt; font-family:Palatino Linotype">By:</P>
</TD><TD style="border-bottom:0.5pt solid #000000" valign=top width=306>&nbsp;</TD></TR>
<TR><TD valign=top width=301.2>&nbsp;</TD><TD valign=top width=342 colspan=2><P style="margin:0pt; padding-left:21.6pt; font-family:Palatino Linotype">Kevin F. Pickard<BR>
Interim Chief Financial Officer <BR>
(principal accounting and financial officer)</P>
</TD></TR>
</TABLE>
<P style="margin:0pt; text-indent:14.4pt; font-family:Palatino Linotype"><B><BR></B></P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype">In accordance with the requirements of the Securities Act of&nbsp;1933, this registration statement was signed by the following persons in the capacities and on the dates stated:</P>
<TABLE style="font-size:10pt" cellspacing=0 align=center><TR><TD valign=bottom width=44.8><P style="margin:0pt; font-family:Palatino Linotype">By:</P>
</TD><TD style="border-bottom:1pt solid #000000" valign=bottom width=187.133>&nbsp;</TD><TD valign=top width=15.733>&nbsp;</TD><TD valign=top width=286.8><P style="margin:0pt; font-family:Palatino Linotype">Interim Administrative Chief Executive Officer and Director </P>
</TD><TD valign=bottom width=119><P style="margin:0pt; font-family:Palatino Linotype">May&nbsp;`16,&nbsp;2008</P>
</TD></TR>
<TR><TD valign=bottom width=44.8>&nbsp;</TD><TD valign=bottom width=187.133><P style="margin-top:0pt; margin-bottom:8.35pt; font-family:Palatino Linotype">Rowland Perkins</P>
</TD><TD valign=top width=15.733>&nbsp;</TD><TD valign=top width=286.8>&nbsp;</TD><TD valign=bottom width=119>&nbsp;</TD></TR>
<TR><TD valign=bottom width=44.8><P style="margin:0pt; font-family:Palatino Linotype">By:</P>
</TD><TD style="border-bottom:0.5pt solid #000000" valign=bottom width=187.133>&nbsp;</TD><TD valign=top width=15.733>&nbsp;</TD><TD valign=top width=286.8><P style="margin:0pt; font-family:Palatino Linotype">Chief Executive Officer, President and Director</P>
</TD><TD valign=bottom width=119><P style="margin:0pt; font-family:Palatino Linotype">May&nbsp;`16,&nbsp;2008</P>
</TD></TR>
<TR><TD valign=bottom width=44.8>&nbsp;</TD><TD valign=bottom width=187.133><P style="margin-top:0pt; margin-bottom:8.35pt; font-family:Palatino Linotype">Lowell T. Harmison</P>
</TD><TD valign=top width=15.733>&nbsp;</TD><TD valign=top width=286.8>&nbsp;</TD><TD valign=bottom width=119>&nbsp;</TD></TR>
<TR><TD valign=bottom width=44.8><P style="margin:0pt; font-family:Palatino Linotype">By:</P>
</TD><TD style="border-bottom:0.5pt solid #000000" valign=bottom width=187.133>&nbsp;</TD><TD valign=top width=15.733>&nbsp;</TD><TD valign=top width=286.8><P style="margin:0pt; font-family:Palatino Linotype">Director</P>
</TD><TD valign=bottom width=119><P style="margin:0pt; font-family:Palatino Linotype">May&nbsp;`16,&nbsp;2008</P>
</TD></TR>
<TR><TD valign=bottom width=44.8>&nbsp;</TD><TD valign=bottom width=187.133><P style="margin-top:0pt; margin-bottom:8.35pt; font-family:Palatino Linotype">Jennifer Black</P>
</TD><TD valign=top width=15.733>&nbsp;</TD><TD valign=top width=286.8>&nbsp;</TD><TD valign=bottom width=119>&nbsp;</TD></TR>
<TR><TD valign=bottom width=44.8><P style="margin:0pt; font-family:Palatino Linotype">By:</P>
</TD><TD style="border-bottom:0.5pt solid #000000" valign=bottom width=187.133>&nbsp;</TD><TD valign=top width=15.733>&nbsp;</TD><TD valign=top width=286.8><P style="margin:0pt; font-family:Palatino Linotype">Director</P>
</TD><TD valign=bottom width=119><P style="margin:0pt; font-family:Palatino Linotype">May&nbsp;`16,&nbsp;2008</P>
</TD></TR>
<TR><TD valign=bottom width=44.8>&nbsp;</TD><TD valign=bottom width=187.133><P style="margin-top:0pt; margin-bottom:8.35pt; font-family:Palatino Linotype">Charles Harrison</P>
</TD><TD valign=top width=15.733>&nbsp;</TD><TD valign=top width=286.8>&nbsp;</TD><TD valign=bottom width=119>&nbsp;</TD></TR>
<TR><TD valign=bottom width=44.8><P style="margin:0pt; font-family:Palatino Linotype">By:</P>
</TD><TD style="border-bottom:0.5pt solid #000000" valign=bottom width=187.133>&nbsp;</TD><TD valign=top width=15.733>&nbsp;</TD><TD valign=top width=286.8><P style="margin:0pt; font-family:Palatino Linotype">Director</P>
</TD><TD valign=bottom width=119><P style="margin:0pt; font-family:Palatino Linotype">May&nbsp;`16,&nbsp;2008</P>
</TD></TR>
<TR><TD valign=bottom width=44.8>&nbsp;</TD><TD valign=bottom width=187.133><P style="margin-top:0pt; margin-bottom:8.35pt; font-family:Palatino Linotype">Robert E. Windom</P>
</TD><TD valign=top width=15.733>&nbsp;</TD><TD valign=top width=286.8>&nbsp;</TD><TD valign=bottom width=119>&nbsp;</TD></TR>
<TR><TD valign=bottom width=44.8><P style="margin:0pt; font-family:Palatino Linotype">By:</P>
</TD><TD style="border-bottom:0.5pt solid #000000" valign=bottom width=187.133>&nbsp;</TD><TD valign=top width=15.733>&nbsp;</TD><TD valign=top width=286.8><P style="margin:0pt; font-family:Palatino Linotype">Director</P>
</TD><TD valign=bottom width=119><P style="margin:0pt; font-family:Palatino Linotype">May&nbsp;`16,&nbsp;2008</P>
</TD></TR>
<TR><TD valign=bottom width=44.8>&nbsp;</TD><TD valign=bottom width=187.133><P style="margin-top:0pt; margin-bottom:8.35pt; font-family:Palatino Linotype">Jay A. Johnson</P>
</TD><TD valign=top width=15.733>&nbsp;</TD><TD valign=top width=286.8>&nbsp;</TD><TD valign=bottom width=119>&nbsp;</TD></TR>
<TR><TD valign=bottom width=44.8><P style="margin:0pt; font-family:Palatino Linotype">By:</P>
</TD><TD style="border-bottom:0.5pt solid #000000" valign=bottom width=187.133>&nbsp;</TD><TD valign=top width=15.733>&nbsp;</TD><TD valign=top width=286.8><P style="margin:0pt; font-family:Palatino Linotype">Director</P>
</TD><TD valign=bottom width=119><P style="margin:0pt; font-family:Palatino Linotype">May&nbsp;`16,&nbsp;2008</P>
</TD></TR>
<TR><TD valign=bottom width=44.8>&nbsp;</TD><TD valign=bottom width=187.133><P style="margin-top:0pt; margin-bottom:8.35pt; font-family:Palatino Linotype">Lee B. Ehrlichman</P>
</TD><TD valign=top width=15.733>&nbsp;</TD><TD valign=top width=286.8>&nbsp;</TD><TD valign=bottom width=119>&nbsp;</TD></TR>
</TABLE>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype"><BR></P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype"><BR>
<BR></P>
<P style="margin:0pt; text-indent:14.4pt; line-height:11pt; font-family:Palatino Linotype; font-size:9pt" align=center>-5-</P>
<P style="margin:0pt; text-indent:14.4pt; font-family:Palatino Linotype; font-size:9pt"><BR></P>
<P style="margin-top:0pt; margin-bottom:8.35pt; text-indent:14.4pt; font-family:Palatino Linotype"><BR></P>
</BODY>
</HTML>
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{"company-data": {"conformed-name": "SIGNALIFE, INC.", "cik": "0000810365", "assigned-sic": "3845", "irs-number": "870441351", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-151009", "film-number": "08845451"}, "business-address": {"street1": "531 SOUTH MAIN STREET", "street2": "SUITE 301", "city": "GREENVILLE", "state": "SC", "zip": "29601", "phone": "(864) 233-2300"}, "mail-address": {"street1": "531 SOUTH MAIN STREET", "street2": "SUITE 301", "city": "GREENVILLE", "state": "SC", "zip": "29601"}, "former-company": [{"former-conformed-name": "RECOM MANAGED SYSTEMS, INC.", "date-changed": "20050912"}, {"former-conformed-name": "RECOM MANAGED SYSTEMS INC DE/", "date-changed": "19990309"}, {"former-conformed-name": "ROCOM MANAGED SYSTEMS INC", "date-changed": "19990309"}]}
Converted by EDGARwiz
As filed with the Securities and Exchange Commission on May 19, 2008
Commission File No. _______
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
_________________
Form S-8
Registration Statement Under The Securities Act Of 1933
Signalife, Inc.
(Exact name of registrant as specified in its charter)
Delaware
(State or other jurisdiction of
incorporation or organization)
87-0441351
(I.R.S. Employer
Identification No.)
Common shares available and reserved for issuance under the Signalife, Inc. 2006 Omnibus Equity Compensation Plan
(
Full title of plan(s))
Rowland Perkins
Interim Administrative Chief Executive Officer
Signalife, Inc.
531 South Main Street, Suite 301
Greenville, South Carolina 29601
(864) 233-2300
(
Name and address of agent for service of process)
(Telephone number, including area code, of agent for service of process)
Copies to
John M. Woodbury, Jr., Esq.
7251 Owensmouth Ave, Suite 7
Canoga Park, California  91303
(818) 883-1767
Calculation of Registration Fee
Title of Securities to be Registered
Amount
to be
Registered(1)
Proposed
Maximum
Offering Price
Per Share
Proposed
Maximum
Aggregate
Offering Price
Amount
of
Registration Fee
Common stock
5,657,334
$           0.38 (2)
$     2,149,786.92
$          84.49
Total
5,657,334
$     2,149,786.92
$          84.49
(1)
Pursuant to SEC Rule 416(a), also covers additional common shares that may be offered to prevent dilution as a result of stock splits, stock dividends or similar transactions relating to these shares.
(2)
Pursuant to Rule 457(h)(1) and 457(c), the filing fee is computed upon the basis of the average of the high and low prices reported by the American Stock Exchange as of the close of market on May 15, 2008.
PART I
INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS
Items 1 and 2.
Plan Information; Registrant Information And Employee Plan Annual Information
Not Applicable
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item
3
Incorporation Of Documents By Reference
We incorporate by reference into this prospectus the documents listed below or excerpts therefrom, as the case may be, as well as all other documents we may file with the SEC pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act after the date of this registration statement and prior to the filing of a post-effective amendment to this registration statement which indicates that all common shares offered under this registration statement have been sold, or which deregisters all common shares offered under this registration statement then remaining unsold::
(1)
our annual report on form 10-KSB filed for our fiscal year ended December 31, 2007, as filed with the Securities and Exchange Commission on April 3, 2008 pursuant to Section 13(a) of the Exchange Act of 1934, as it may be amended from time-to-time;
(2)
all other reports we have filed pursuant to Section 13(a) or 15(d) of the Exchange Act since December 31, 2007; and
(3)
the description of our common shares contained in that section captioned "
Description of Equity Securities—Common Shares
" contained in our registration statement on form SB-2 (SEC file no. 333—148515) as filed with the Securities and Exchange Commission on January 8, 2008 and declared effective on January 16, 2008.
All documents we may file with the Securities and Exchange Commission pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act after the date of this registration statement and prior to the filing of a post-effective amendment to this registration statement which indicates that all common shares offered under this registration statement have been sold, or which deregisters all common shares offered under this registration statement then remaining unsold, shall be deemed to be incorporated by reference in the registration statement and to be a part hereof from the date of filing of such documents.
For purposes of this registration statement, any document or any statement contained in a document incorporated or deemed to be incorporated herein by reference shall be deemed to be modified or superseded to the extent that a subsequently filed document or a statement contained herein or in any other subsequently filed document which also is or is deemed to be incorporated herein by reference modifies or supersedes such document or such statement in such document.  Any statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this registration statement.
Notwithstanding the above, information that is "furnished to" the SEC shall not be deemed "filed with" the SEC and shall not be deemed incorporated by reference into this registration statement.
Item 4.
Description of Securities
Not applicable—the common shares to be offered and sold under this prospectus are registered under Section 12(b) of the Securities Exchange Act of 1934.
-2-
Item 5.
Interests of Named Experts and Counsel
Not applicable.
Item 6
Indemnification Of Directors And Officers
Our Certificate of Incorporation provides shall that we shall, to the maximum extent and in the manner under Delaware corporate law, indemnify each of our directors and officers against judgments, fines, settlements and other amounts, including expenses such as attorneys' fees, actually and reasonably incurred in connection with any proceeding, arising by reason of the fact that such person is or was an agent of the corporation.  We may also have contractual indemnification obligations under our individual agreements with our directors, officers and employees.
The foregoing indemnification obligations could result in our company incurring substantial expenditures to cover the cost of settlement or damage awards against directors, officers and employees, which we may be unable to recoup.  These provisions and resultant costs may also discourage our company from bringing a lawsuit against directors, officers and employees for breaches of their fiduciary duties, including breaches resulting from negligent or grossly negligent behavior, except under certain situations defined by statute, and may similarly discourage the filing of derivative litigation by our shareholders against our directors, officers and employees, even though such actions, if successful, might otherwise benefit our company and shareholders.  We believe that the indemnification provisions in our Articles of Incorporation are necessary to attract and retain qualified persons as directors and officers.
Insofar as indemnification for liabilities arising under the Securities Act of 1933 may be permitted to our directors, officers and controlling persons pursuant to the foregoing provisions, or otherwise, we have been advised that in the opinion of the SEC such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable.  In the event that a claim for indemnification against such liabilities, other than the payment by the registrant of expenses incurred or paid by a director, officer or controlling person of the registrant in the successful defense of any action, suit or proceeding, is asserted by such director, officer or controlling person in connection with the securities being registered, we will, unless in the opinion of our counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by us is against public policy as expressed in the Securities Act and we will be governed by the final adjudication of such issue.
Item 7
Exemption From Registration Claimed
Not applicable.
Item 8
Exhibits And Financial Statement Schedules
3.1
Restated Certificate Of Incorporation Of Signalife, Inc. filed by the Delaware Secretary of State on May 5, 2006 (1)
3.2
Restated Bylaws adopted as of May 5, 2006 (1)
4
Signalife 2006 Omnibus Equity Compensation Plan, as adopted effective as of June 7, 2006 (2)
5.
Legal opinion by John M. Woodbury, Jr., Esq. *
23.1
Consent of legal counsel (John M. Woodbury, Jr.) (3)
23.2
Consent of Independent Registered Public Accounting Firm (Elliott Davis, LLC) *
*
Filed herewith
(1)
Previously filed as an exhibit to our current report on form 8-K filed with the SEC on May 11, 2006.
-3-
(2)
Previously filed as an exhibit to our registration statement on form S-8 filed with the SEC on June 12, 2006.
(3)
Included in legal opinion filed as exhibit 5 *
Item 9
Undertakings
We hereby undertake to:
1.
File, during any period in which we offer or sell securities, a post-effective amendment to this registration statement to:
(i)
include any prospectus required by section 10(a)(3) of the Securities Act (unless incorporated by reference in this registration statement from periodic reports filed by the issuer under the Exchange Act),
(ii)
reflect in the prospectus any facts or events which, individually or together, represent a fundamental change in the information in the registration statement; and notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospects filed with the SEC under Rule 424(b) if, in the aggregate, the changes in the volume and price represent no more than a 20% change in the maximum aggregate offering price set forth in the "Calculation of Registration Fee" table on the face page of the effective registration statement (unless incorporated by reference in this registration statement from periodic reports filed by the issuer under the Exchange Act); or
(iii)
include any additional or changed material information on the plan of distribution.
2.
For determining liability under the Securities Act, treat each post-effective amendment as a new registration statement of the securities offered, and the offering of the securities at that time to be the initial bona fide offering.
3.
File a post-effective amendment to remove from registration any of the securities that remain unsold at the end of the offering.
4.
For determining any liability under the Securities Act, treat each post-effective amendment that contains a form of prospectus as a new registration statement for the securities offered in the registration statement, and that offering of the securities at that time as the initial bona fide offering of those securities.  Insofar as indemnification for liabilities arising under the Securities Act may be permitted to our directors, officers and controlling persons under the foregoing provisions or otherwise, we have been advised that in the opinion of the SEC such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable.  If a claim for indemnification against such liabilities (other than our payment of expenses incurred or paid by any of our directors, officers or controlling persons in the successful defense of any action, suit, or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered, we will, unless in the opinion of our counsel the matter has been settled by a controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by us is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.
-4-
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements of filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Greenville, State of South Carolina, on May 16 2008.
SIGNALIFE, INC.
By:
Rowland Perkins
Interim Administrative Chief Executive Officer
(co-principal executive officer)
By:
Kevin F. Pickard
Interim Chief Financial Officer
(principal accounting and financial officer)
In accordance with the requirements of the Securities Act of 1933, this registration statement was signed by the following persons in the capacities and on the dates stated:
By:
Interim Administrative Chief Executive Officer and Director
May `16, 2008
Rowland Perkins
By:
Chief Executive Officer, President and Director
May `16, 2008
Lowell T. Harmison
By:
Director
May `16, 2008
Jennifer Black
By:
Director
May `16, 2008
Charles Harrison
By:
Director
May `16, 2008
Robert E. Windom
By:
Director
May `16, 2008
Jay A. Johnson
By:
Director
May `16, 2008
Lee B. Ehrlichman
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