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<TITLE>01242001 S8 DOC</TITLE>
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<p align="right"><font size="3" color="FF0000"><strong>
As filed with the Securities and Exchange Commission on January 25, 2001<br>
                                               Registration No. _________
</strong></font></p>

<DIV align=left>
<HR align=left SIZE=2 width="100%">
</DIV>
<DIV align=left>
<HR align=left SIZE=2 width="100%">
</DIV>

<p align="center"><font size="3"><strong>UNITED STATES</br>
SECURITIES AND EXCHANGE COMMISSION</br>
Washington, D.C. 20549</strong></font></p>

<HR align=center SIZE=2 width="25%">
<br>
<p align="center"><font size="5"><strong>FORM S-8</strong></center></font></p>
<HR align=center SIZE=2 width="25%">

<p align="center"><font size="3"><strong>
          REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933


</strong></font></p>

<p align="center"><font size="6" color="#0000FF"><strong>
                             <u>CELL GENESYS, INC.</u>
</strong></font></br>
<font size="2">
      (Exact Name of Registrant as Specified in its Charter)
</font>

<P>&nbsp;
<TABLE COLS=2 WIDTH="100%" >
<TR>
<TD>
<font size="3"><strong>
<CENTER><u>Delaware</u></CENTER>
</font></strong>
</TD>
<TD>
<font size="3"><strong>
<CENTER><u> 94-3061375 </u></CENTER>
</font></strong>
</TD>
</TR>
<TR>
<TD>
<font size="2">
<CENTER>&nbsp; (State of Incorporation)&nbsp;</CENTER>
</font>
</TD>
<TD>
<font size="2">
<CENTER>(IRS Employer Identification Number)</CENTER>
</font>
</TD>
</TR>
</TABLE>
<BR>

<p align="center"><font size="3"><strong>
                           342 Lakeside Drive<br>
                      <u>Foster City, California &nbsp;&nbsp;94404<br>
</strong></font></u>
<font size="2">
       (Address of Principal Executive Offices)</P>

<HR align=center SIZE=2 width="25%">

</font></p>

<p align="center"><font size="4" color="#0000FF"><strong>

                           2001 Nonstatutory Stock Option Plan
</strong></font></br>
<font size="2">
      (Full Title of the Plan)
</font></p>
<HR align=center SIZE=2 width="25%">

<p align="center"><font size="3"><strong>
                              Matthew J. Pfeffer<br>
                            Chief Financial Officer<br>
                             Cell Genesys, Inc.<br>
                           342 Lakeside Drive<br>
                         Foster City, California &nbsp;&nbsp;94404<br>
                               (650) 425-4400
</strong></font><br>

<font size="2">
          (Name, address, including zip code, and telephone number,<br>
                  including area code, of agent for service)
</font></p>

<HR WIDTH="25%">

<p align="center"><font size="3"><strong>
                                   Copies to:<br>
<br><i>
                              Herbert P. Fockler, Esq.<br>
                               Tracy Donsky, Esq.</i><br>
                        Wilson Sonsini Goodrich & Rosati<br>
                            Professional Corporation<br>
                               650 Page Mill Road<br>
                            Palo Alto, CA 94304-1050<br>
                                 (650) 493-9300<br>
</strong></font></p>

<p align="center"><font size="3"><strong>
          Approximate date of commencement of proposed sale to the public:
</strong></font></p>
<p align="center"><font size="3">
  As soon as practicable after the effective date of this Registration Statement.
</font></p>
If any of the securities being registered on this Form are to be offered on a delayed
or continuous basis pursuant to Rule 415 under the Securities Act of 1933, check the
following box. &nbsp;&nbsp;[&nbsp;&nbsp;&nbsp;]

<p align="center"><font size="3"><strong>
                         CALCULATION OF REGISTRATION FEE
</strong>
<HR align=left SIZE=2 width="100%">

<TABLE CELLSPACING=0 BORDER=0 CELLPADDING=5 WIDTH=732>
<TR><TD WIDTH="30%" VALIGN="BOTTOM">
<B><FONT SIZE=2><P ALIGN="CENTER"> Title of Each Class of Securities to be Registered
</B>&#9;</FONT></TD>
<TD WIDTH="22%" VALIGN="BOTTOM">
<B><FONT SIZE=2><P ALIGN="CENTER"> Amount to be Registered
</B>&#9;</FONT></TD>
<TD WIDTH="16%" VALIGN="BOTTOM">
<B><FONT SIZE=2><P ALIGN="CENTER"> Proposed Maximum Offering Price Per Share(1)
</B>&#9;</FONT></TD>
<TD WIDTH="16%" VALIGN="BOTTOM">
<B><FONT SIZE=2><P ALIGN="CENTER"> Proposed Maximum Aggregate Offering Price(1)
</B>&#9;</FONT></TD>
<TD WIDTH="16%" VALIGN="BOTTOM">
<B><FONT SIZE=2><P ALIGN="CENTER"> Amount of Registration Fee
</B>&#9;</FONT></TD>
</TR>

<TR><TD WIDTH="30%" VALIGN="BOTTOM">
<FONT SIZE=2><P ALIGN="CENTER"> Common Stock, $0.001 par value<br>
2001 Nonstatutory Stock Option Plan
&#9;</FONT></TD>
<TD WIDTH="22%" VALIGN="BOTTOM">
<FONT SIZE=2><P ALIGN="CENTER">2,000,000
&#9;</FONT></TD>
<TD WIDTH="16%" VALIGN="BOTTOM">
<FONT SIZE=2><P ALIGN="CENTER">$18.63
&#9;</FONT></TD>
<TD WIDTH="16%" VALIGN="BOTTOM">
<FONT SIZE=2><P ALIGN="CENTER">$37,250,000.00
&#9;</FONT></TD>
<TD WIDTH="16%" VALIGN="BOTTOM">
<FONT SIZE=2><P ALIGN="CENTER">$9,834.00
&#9;</FONT></TD>
</TR>

<TR><TD WIDTH="30%" VALIGN="BOTTOM">
<FONT SIZE=2><P ALIGN="CENTER">TOTAL
&#9;</FONT></TD>
<TD WIDTH="22%" VALIGN="BOTTOM">
<FONT SIZE=2><P ALIGN="CENTER">2,000,000
&#9;</FONT></TD>
<TD WIDTH="16%" VALIGN="BOTTOM">
<FONT SIZE=2><P ALIGN="CENTER">$18.63
&#9;</FONT></TD>
<TD WIDTH="16%" VALIGN="BOTTOM">
<FONT SIZE=2><P ALIGN="CENTER">$37,250,000.00
&#9;</FONT></TD>
<TD WIDTH="16%" VALIGN="BOTTOM">
<FONT SIZE=2><P ALIGN="CENTER">$9,834.00
&#9;</FONT></TD>
</TR>
</TABLE>

<HR align=left SIZE=2 width="100%">


<font size="2">

<OL>

<FONT SIZE=1><P ALIGN="JUSTIFY"><LI>Estimated in accordance with
Rule&nbsp;457(h) under the Securities Act solely for the purpose of calculating
the registration fee.  In accordance with Rule 457(h), the computation is based
on the average of the high and low sale prices for the Common Stock of Cell
Genesys, Inc. reported by the Nasdaq National Market on January 22, 2001 which
was $18.63.</LI></P></OL>


<B><FONT SIZE=3><P ALIGN="CENTER">CELL GENESYS, INC.</P>
<P ALIGN="CENTER">REGISTRATION STATEMENT ON FORM S-8</P>
<P ALIGN="CENTER">PART II</P>
<P ALIGN="CENTER">INFORMATION REQUIRED IN REGISTRATION STATEMENT</P>
<P ALIGN="JUSTIFY">Item 3.  Incorporation of Document by Reference.</P>
</B><P ALIGN="JUSTIFY">There are hereby incorporated by reference in this
Registration Statement the following documents and information previously filed
with the Securities and Exchange Commission (the &quot;COMMISSION&quot;):</P>
<OL TYPE="a">

<OL TYPE="a">

<P ALIGN="JUSTIFY"><LI>The Company's Annual Report on Form 10-K for the fiscal
year ended December&nbsp;31, 1999 filed pursuant to Section&nbsp;13(a) or 15(d)
of the Securities Exchange Act of 1934, as amended (the &quot;EXCHANGE
ACT&quot;).</LI></P>
<P ALIGN="JUSTIFY"><LI>The Company's Quarterly Report on Form 10-Q for the
fiscal quarter ended March&nbsp;31, 2000, filed pursuant to section 13(a) of the
Exchange Act. </LI></P>
<P ALIGN="JUSTIFY"><LI>The Company's Quarterly Report on Form 10-Q for the
fiscal quarter ended June 30, 2000, filed pursuant to Section 13(a) or 15(d) of
the Exchange Act.</LI></P>
<P ALIGN="JUSTIFY"><LI>The Company's Quarterly Report on Form 10-Q for the
fiscal quarter ended September 30, 2000, filed pursuant to Section 13(a) or
15(d) of the Exchange Act.</LI></P>
<P ALIGN="JUSTIFY"><LI>The Company's Current Report on Form 8-K, filed with the
Commission on January 27, 2000 pursuant to Section 13(a) or 15(d) of the
Exchange Act. </LI></P>
<P ALIGN="JUSTIFY"><LI>The description of the Registrant's Common Stock and
associated preferred share purchase rights, contained in the Registrant's
Registration Statement on Form 8-A filed with the Commission on March&nbsp;24,
1992 and August&nbsp;8, 1995, registering such shares and associated rights
pursuant to Section&nbsp;12 of the Exchange Act, including any amendment or
report updating such descriptions.</LI></P></OL>
</OL>

<P ALIGN="JUSTIFY">All documents filed by the Company pursuant to Sections
13(a), 13(c), 14 and 15(d) of the Exchange Act subsequent to the filing of this
Registration Statement, and prior to the filing of a post-effective amendment
that indicates that all securities offered have been sold or that deregisters
all securities then remaining unsold, shall be deemed to be incorporated by
reference in the Registration Statement and to be part hereof from the date of
filing such documents.</P>
<B><P ALIGN="JUSTIFY">Item 4.  Description of Securities.</P>
</B><P ALIGN="JUSTIFY">Not applicable.</P>
<B><P ALIGN="JUSTIFY">Item 5.  Interests of Named Experts and Counsel.</P>
</B><P ALIGN="JUSTIFY">Not applicable.</P>
<B><P ALIGN="JUSTIFY">Item 6.  Indemnification of Directors and Officers.</P>
</B><P ALIGN="JUSTIFY">Section&nbsp;145 of the Delaware General Corporation Law
authorizes a court to award or a corporation's Board of Directors to grant
indemnification to directors and officers in terms sufficiently broad to permit
such indemnification under certain circumstances for liabilities (including
reimbursement for expenses incurred) arising under the Securities Act of 1933
(the &quot;SECURITIES ACT&quot;), as amended.  The Company has included in its
Certificate of Incorporation a provision that to the fullest extent permitted by
Delaware law, the Company's directors will not be liable for monetary damages
for breach of the directors' fiduciary duty of care to the Company and its
stockholders.  In addition, the Company's Bylaws provide that the Company is
required to indemnify its officers and directors to the fullest extent permitted
by Delaware law, including those circumstances in which indemnification would
otherwise be discretionary, and that the Company is required to advance expenses
to its officers and directors as incurred.  Further, the Company intends to
enter into indemnification agreements with its officers and directors, providing
such individuals indemnification to the maximum extent permitted by the Delaware
General Corporation Law.</P>
<P ALIGN="JUSTIFY">Insofar as indemnification for liabilities arising under the
Securities Act may be permitted to directors, officers and controlling persons
of the Company pursuant to the Delaware General Corporation Law, the foregoing
Bylaw provision or any Indemnification Agreement, the Company has been informed
that in the opinion of the Securities and Exchange Commission such
indemnification is against public policy as expressed in the Securities Act and
is therefore unenforceable.</P>
<B><P ALIGN="JUSTIFY">Item 7.  Exemption from Registration Claimed.</P>
</B><P ALIGN="JUSTIFY">Not applicable.</P>


<B><P ALIGN="JUSTIFY">Item 8.  Exhibits.</P>
</B><P ALIGN="JUSTIFY"></P></FONT>
<P ALIGN="CENTER"><CENTER><TABLE CELLSPACING=0 BORDER=0 CELLPADDING=7 WIDTH=553>
<TR><TD WIDTH="24%" VALIGN="BOTTOM">
<B><FONT SIZE=3><P>Exhibit<BR>
Number</B></FONT></TD>
<TD WIDTH="76%" VALIGN="BOTTOM">
<B><FONT SIZE=3><P ALIGN="CENTER">Description</B></FONT></TD>
</TR>
<TR><TD WIDTH="24%" VALIGN="TOP">
<FONT SIZE=3><P>4.1</FONT></TD>
<TD WIDTH="76%" VALIGN="TOP">
<FONT SIZE=3><P ALIGN="JUSTIFY">2001 Nonstatutory Stock Option Plan.</FONT></TD>
</TR>
<TR><TD WIDTH="24%" VALIGN="TOP">
<FONT SIZE=3><P>5.1</FONT></TD>
<TD WIDTH="76%" VALIGN="TOP">
<FONT SIZE=3><P ALIGN="JUSTIFY">Opinion of Wilson Sonsini Goodrich &amp; Rosati,
P.C. as to legality of securities being registered.</FONT></TD>
</TR>
<TR><TD WIDTH="24%" VALIGN="TOP">
<FONT SIZE=3><P>23.1</FONT></TD>
<TD WIDTH="76%" VALIGN="TOP">
<FONT SIZE=3><P ALIGN="JUSTIFY">Consent of Wilson Sonsini Goodrich &amp; Rosati,
P.C. (contained in Exhibit 5.1).</FONT></TD>
</TR>
<TR><TD WIDTH="24%" VALIGN="TOP">
<FONT SIZE=3><P>23.2</FONT></TD>
<TD WIDTH="76%" VALIGN="TOP">
<FONT SIZE=3><P ALIGN="JUSTIFY">Consent of Ernst &amp; Young LLP, Independent
Auditors.</FONT></TD>
</TR>
<TR><TD WIDTH="24%" VALIGN="TOP">
<FONT SIZE=3><P>24.1</FONT></TD>
<TD WIDTH="76%" VALIGN="TOP">
<FONT SIZE=3><P ALIGN="JUSTIFY">Power of Attorney (see page II-4).</FONT></TD>
</TR>
</TABLE>
</CENTER></P>

<B><FONT SIZE=3><P ALIGN="JUSTIFY">Item 9.  Undertakings.</P>
</B><P ALIGN="JUSTIFY">(a)&#9;The undersigned Registrant hereby undertakes:</P>

<DIR>
<P ALIGN="JUSTIFY">(1)&#9;To file, during any period in which offers or sales
are being made, a post-effective amendment to this registration statement:</P>

<DIR>
<P ALIGN="JUSTIFY">(i)&#9;To include any prospectus required by
section&nbsp;10(a)(3) of the Securities Act of 1933;</P>

<P ALIGN="JUSTIFY">(ii)&#9;To reflect in the prospectus any facts or events
arising after the effective date of the registration statement (or the most
recent post-effective amendment thereof) which, individually or in the
aggregate, represent a fundamental change in the information set forth in the
registration statement.  Notwithstanding the foregoing, any increase or decrease
in volume of securities offered (if the total dollar value of securities offered
would not exceed that which was registered) and any deviation from the low or
high end of the estimated maximum offering range may be reflected in the form of
prospectus filed with the Commission pursuant to Rule 424(b) if, in the
aggregate, the changes in volume and price represent no more than a 20 percent
change in the maximum aggregate offering price set forth in the "Calculation of
Registration Fee" table in the effective registration statement;</P>

<P ALIGN="JUSTIFY">(iii)&#9;To include any material information with respect to
the plan of distribution not previously disclosed in the registration statement
or any material change to such information in the registration statement.</P>
<I><P ALIGN="JUSTIFY">Provided</I>, <I>however</I>, that
paragraphs&nbsp;(a)(1)(i) and (a)(1)(ii) do not apply if the information
required to be included in a post-effective amendment by those paragraphs is
contained in periodic reports filed by the Registrant pursuant to
section&nbsp;13 or section&nbsp;15(d) of the Securities Exchange Act of 1934
that are incorporated by reference in this registration statement.</P>

</DIR>

<P ALIGN="JUSTIFY">(2)&#9;That, for the purpose of determining any liability
under the Securities Act of 1933, each such post-effective amendment shall be
deemed to be a new registration statement relating to the securities offered
therein, and the offering of such securities at that time shall be deemed to be
the initial bona fide offering thereof.</P>
<P ALIGN="JUSTIFY">(3)&#9;To remove from registration by means of a post-
effective amendment any of the securities being registered which remain unsold
at the termination of the offering.</P>

</DIR>
<P ALIGN="JUSTIFY">(b)&#9;The undersigned Registrant hereby undertakes that, for
purposes of determining any liability under the Securities Act, each filling of
the Registrant's annual report pursuant to Section&nbsp;13(a) or
Section&nbsp;15(d) of the Exchange Act (and, where applicable, each filing of an
employee benefit plan's annual report pursuant to Section&nbsp;15(d) of the
Exchange Act) that is incorporated by reference in the Registration Statement
shall be deemed to be a new registration statement relating to the securities
offered therein, and the offering of such securities at that time shall be
deemed to be an initial bona fide offering thereof.</P>
<P ALIGN="JUSTIFY">(c)&#9;Insofar as indemnification for liabilities arising
under the Securities Act may be permitted to directors, officers and controlling
persons of the Registrant pursuant to the Delaware General Corporation Law, the
Certificate of Incorporation of the Registrant, the Bylaws of the Registrant,
Indemnification Agreements entered into between the Registrant and its officers
and directors, or otherwise, the Registrant has been advised that in the opinion
of the Securities and Exchange Commission such indemnification is against public
policy as expressed in the Securities Act and is, therefore, unenforceable.  In
the event that a claim for indemnification against such liabilities (other than
the payment by the Registrant of expenses incurred or paid by a director,
officer or controlling person of the Registrant in the successful defense of any
action, suit or proceeding) is asserted by such director, officer or controlling
person in connection with the securities being registered, the Registrant will,
unless in the opinion of its counsel the matter has been settled by controlling
precedent, submit to a court of appropriate jurisdiction the question whether
such indemnification by it is against public policy as expressed in the
Securities Act and will be governed by the final adjudication of such issue.</P>
<B><P ALIGN="CENTER">&nbsp;</P>

<br>
<br>
<br>
<HR WIDTH="85%">
<br>
<br>
<br>

<P ALIGN="CENTER">SIGNATURES</P>
</B><P ALIGN="JUSTIFY">Pursuant to the requirements of the Securities Act of
1933, the Registrant certifies that it has reasonable grounds to believe that it
meets all of the requirements for filing on Form&nbsp;S-8 and has duly caused
this Registration Statement to be signed on its behalf by the undersigned,
thereunto duly authorized, in the City of Foster City, State of California, on
this 25th day of January, 2001.</P><DIR>
<DIR>
<DIR>
<DIR>
<DIR>
<DIR>
<DIR>
<DIR>
<DIR>
<DIR>
<DIR>

<P ALIGN="JUSTIFY">CELL GENESYS, INC.</P>

<P ALIGN="JUSTIFY">By:&#9;<u>/s/ Matt Pfeffer</u></P>
<P ALIGN="JUSTIFY">&#9;Matt Pfeffer<br>
                   &#9;Chief Financial Officer</P></DIR>
</DIR>
</DIR>
</DIR>
</DIR>
</DIR>
</DIR>
</DIR>
</DIR>
</DIR>
</DIR>

<B><P ALIGN="CENTER">POWER OF ATTORNEY</P>
</B><P ALIGN="JUSTIFY">KNOW ALL PERSONS BY THESE PRESENTS, that each person
whose signature appears below hereby constitutes and appoints, Matt Pfeffer, or
his attorney-in-fact, for him in any and all capacities, to sign any and all
amendments to this Registration Statement on Form S-8, and to file the same,
with exhibits thereto and other documents in connection therewith, with the
Securities and Exchange Commission, hereby ratifying and confirming all that
said attorney-in-fact, or his substitute may do or cause to be done by virtue
hereof.</P>
<P ALIGN="JUSTIFY">&nbsp;</P>
<P ALIGN="JUSTIFY">Pursuant to the requirements of the Securities Act of 1933,
this Registration Statement has been signed below by the following persons in
the capacities and on the dates indicated.</P>
<P ALIGN="JUSTIFY"></P></FONT>

<TABLE BORDER=0 CELLSPACING=1 CELLPADDING=7 WIDTH=661>
<TR><TD WIDTH="39%" VALIGN="BOTTOM">
<B><FONT SIZE=3><P ALIGN="CENTER">Signature</B></FONT></TD>
<TD WIDTH="37%" VALIGN="BOTTOM">
<B><FONT SIZE=3><P ALIGN="CENTER">Title</B></FONT></TD>
<TD WIDTH="24%" VALIGN="BOTTOM">
<B><FONT SIZE=2><P ALIGN="CENTER">Date</B></FONT></TD>
</TR>

<TR><TD WIDTH="39%" VALIGN="TOP">
<U><FONT SIZE=3><P>/s/ Stephen A. Sherwin, M.D.<br>
</U>Stephen A. Sherwin, M.D.</FONT></TD>
<TD WIDTH="37%" VALIGN="MIDDLE">
<FONT SIZE=3><P>Chairman of the Board, President, and Chief Executive Officer
(Principal Executive Officer)</FONT></TD>
<TD WIDTH="24%" VALIGN="MIDDLE">
<FONT SIZE=3><P ALIGN="CENTER">January 25, 2001</FONT></TD>
</TR>
<TR><TD WIDTH="39%" VALIGN="TOP">
<U><FONT SIZE=3><P>/s/  Matt Pfeffer<br>
</U>Matt Pfeffer</FONT></TD>
<TD WIDTH="37%" VALIGN="MIDDLE">
<FONT SIZE=3><P>Chief Financial Officer (Principal Financial and Accounting
Officer)</FONT></TD>
<TD WIDTH="24%" VALIGN="MIDDLE">
<FONT SIZE=3><P ALIGN="CENTER">January 25, 2001</FONT></TD>
</TR>
<TR><TD WIDTH="39%" VALIGN="TOP">
<U><FONT SIZE=3><P>/s/ David W. Carter<br>
</U>David W. Carter</FONT></TD>
<TD WIDTH="37%" VALIGN="MIDDLE">
<FONT SIZE=3><P>Director</FONT></TD>
<TD WIDTH="24%" VALIGN="MIDDLE">
<FONT SIZE=3><P ALIGN="CENTER">January 25, 2001</FONT></TD>
</TR>
<TR><TD WIDTH="39%" VALIGN="TOP">
<U><FONT SIZE=3><P>/s/  James M. Gower<br>
</U>James M. Gower</FONT></TD>
<TD WIDTH="37%" VALIGN="MIDDLE">
<FONT SIZE=3><P>Director</FONT></TD>
<TD WIDTH="24%" VALIGN="MIDDLE">
<FONT SIZE=3><P ALIGN="CENTER">January 25, 2001</FONT></TD>
</TR>
<TR><TD WIDTH="39%" VALIGN="TOP">
<U><FONT SIZE=3><P>/s/ John T. Potts, Jr., M.D.<br>
</U>John T. Potts, Jr., M.D.</FONT></TD>
<TD WIDTH="37%" VALIGN="MIDDLE">
<FONT SIZE=3><P>Director</FONT></TD>
<TD WIDTH="24%" VALIGN="MIDDLE">
<FONT SIZE=3><P ALIGN="CENTER">January 25, 2001</FONT></TD>
</TR>
<TR><TD WIDTH="39%" VALIGN="TOP">
<U><FONT SIZE=3><P>/s/  Eugene L. Step<br>
</U>Eugene L. Step</FONT></TD>
<TD WIDTH="37%" VALIGN="MIDDLE">
<FONT SIZE=3><P>Director</FONT></TD>
<TD WIDTH="24%" VALIGN="MIDDLE">
<FONT SIZE=3><P ALIGN="CENTER">January 25, 2001</FONT></TD>
</TR>
<TR><TD WIDTH="39%" VALIGN="TOP">
<U><FONT SIZE=3><P>/s/ Inder M. Verma, Ph.D.<br>
</U>Inder M. Verma, Ph.D.</FONT></TD>
<TD WIDTH="37%" VALIGN="MIDDLE">
<FONT SIZE=3><P>Director</FONT></TD>
<TD WIDTH="24%" VALIGN="MIDDLE">
<FONT SIZE=3><P ALIGN="CENTER">January 25, 2001</FONT></TD>
</TR>
<TR><TD WIDTH="39%" VALIGN="TOP">&nbsp;</TD>
<TD WIDTH="37%" VALIGN="MIDDLE">&nbsp;</TD>
<TD WIDTH="24%" VALIGN="MIDDLE">&nbsp;</TD>
</TR>
</TABLE>

<B><FONT SIZE=3><P ALIGN="CENTER">&nbsp;</P>
<P ALIGN="CENTER">&nbsp;</P>
<P ALIGN="CENTER">SECURITIES AND EXCHANGE COMMISSION</P>
<P ALIGN="CENTER">Washington, D.C. 20549</P>
</B><P ALIGN="JUSTIFY"></P></FONT>


<TABLE BORDER CELLSPACING=1 CELLPADDING=7 WIDTH=662>
<TR><TD VALIGN="MIDDLE">
<B><FONT SIZE=3><P ALIGN="CENTER">EXHIBITS</B></FONT></TD>
</TR>
</TABLE>

<B><FONT SIZE=3><P ALIGN="CENTER">Registration Statement on Form S-8</P>
<P ALIGN="CENTER">CELL GENESYS, INC.</P>
<P ALIGN="CENTER">INDEX TO EXHIBITS</P>
</B><P ALIGN="JUSTIFY"></P></FONT>
<P ALIGN="CENTER"><CENTER><TABLE CELLSPACING=0 BORDER=0 CELLPADDING=7 WIDTH=553>
<TR><TD WIDTH="24%" VALIGN="TOP">
<B><FONT SIZE=3><P>Exhibit<BR>
Number</B></FONT></TD>
<TD WIDTH="76%" VALIGN="TOP">
<B><FONT SIZE=3><P ALIGN="CENTER">Description</B></FONT></TD>
</TR>
<TR><TD WIDTH="24%" VALIGN="TOP">
<FONT SIZE=3><P>4.1</FONT></TD>
<TD WIDTH="76%" VALIGN="TOP">
<FONT SIZE=3><P ALIGN="JUSTIFY">2001 Nonstatutory Stock Option Plan.</FONT></TD>
</TR>
<TR><TD WIDTH="24%" VALIGN="TOP">
<FONT SIZE=3><P>5.1</FONT></TD>
<TD WIDTH="76%" VALIGN="TOP">
<FONT SIZE=3><P ALIGN="JUSTIFY">Opinion of Wilson Sonsini Goodrich &amp; Rosati,
P.C. as to legality of securities being registered.</FONT></TD>
</TR>
<TR><TD WIDTH="24%" VALIGN="TOP">
<FONT SIZE=3><P>23.1</FONT></TD>
<TD WIDTH="76%" VALIGN="TOP">
<FONT SIZE=3><P ALIGN="JUSTIFY">Consent of Wilson Sonsini Goodrich &amp; Rosati,
P.C. (contained in Exhibit 5.1).</FONT></TD>
</TR>
<TR><TD WIDTH="24%" VALIGN="TOP">
<FONT SIZE=3><P>23.2</FONT></TD>
<TD WIDTH="76%" VALIGN="TOP">
<FONT SIZE=3><P ALIGN="JUSTIFY">Consent of Ernst &amp; Young LLP, Independent
Auditors.</FONT></TD>
</TR>
<TR><TD WIDTH="24%" VALIGN="TOP">
<FONT SIZE=3><P>24.1</FONT></TD>
<TD WIDTH="76%" VALIGN="TOP">
<FONT SIZE=3><P ALIGN="JUSTIFY">Power of Attorney (see page II-4).</FONT></TD>
</TR>
</TABLE>
</CENTER></P>

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{"company-data": {"conformed-name": "CELL GENESYS INC", "cik": "0000865231", "assigned-sic": "2834", "irs-number": "943061375", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-54376", "film-number": "1516070"}, "business-address": {"street1": "342 LAKESIDE DR", "city": "FOSTER CITY", "state": "CA", "zip": "94404", "phone": "6504254400"}, "mail-address": {"street1": "342 LAKESIDE DR", "city": "FOSTER CITY", "state": "CA", "zip": "94404"}}
01242001 S8 DOC
As filed with the Securities and Exchange Commission on January 25, 2001
Registration No. _________
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-8
REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933
CELL GENESYS, INC.
(Exact Name of Registrant as Specified in its Charter)
Delaware
94-3061375
(State of Incorporation)
(IRS Employer Identification Number)
342 Lakeside Drive
Foster City, California   94404
(Address of Principal Executive Offices)
2001 Nonstatutory Stock Option Plan
(Full Title of the Plan)
Matthew J. Pfeffer
Chief Financial Officer
Cell Genesys, Inc.
342 Lakeside Drive
Foster City, California   94404
(650) 425-4400
(Name, address, including zip code, and telephone number,
including area code, of agent for service)
Copies to:
Herbert P. Fockler, Esq.
Tracy Donsky, Esq.
Wilson Sonsini Goodrich & Rosati
Professional Corporation
650 Page Mill Road
Palo Alto, CA 94304-1050
(650) 493-9300
Approximate date of commencement of proposed sale to the public:
As soon as practicable after the effective date of this Registration Statement.
If any of the securities being registered on this Form are to be offered on a delayed
or continuous basis pursuant to Rule 415 under the Securities Act of 1933, check the
following box.   [   ]
CALCULATION OF REGISTRATION FEE
Title of Each Class of Securities to be Registered
Amount to be Registered
Proposed Maximum Offering Price Per Share(1)
Proposed Maximum Aggregate Offering Price(1)
Amount of Registration Fee
Common Stock, $0.001 par value
2001 Nonstatutory Stock Option Plan
2,000,000
$18.63
$37,250,000.00
$9,834.00
TOTAL
2,000,000
$18.63
$37,250,000.00
$9,834.00
Estimated in accordance with
Rule 457(h) under the Securities Act solely for the purpose of calculating
the registration fee.  In accordance with Rule 457(h), the computation is based
on the average of the high and low sale prices for the Common Stock of Cell
Genesys, Inc. reported by the Nasdaq National Market on January 22, 2001 which
was $18.63.
CELL GENESYS, INC.
REGISTRATION STATEMENT ON FORM S-8
PART II
INFORMATION REQUIRED IN REGISTRATION STATEMENT
Item 3.  Incorporation of Document by Reference.
There are hereby incorporated by reference in this
Registration Statement the following documents and information previously filed
with the Securities and Exchange Commission (the "COMMISSION"):
The Company's Annual Report on Form 10-K for the fiscal
year ended December 31, 1999 filed pursuant to Section 13(a) or 15(d)
of the Securities Exchange Act of 1934, as amended (the "EXCHANGE
ACT").
The Company's Quarterly Report on Form 10-Q for the
fiscal quarter ended March 31, 2000, filed pursuant to section 13(a) of the
Exchange Act.
The Company's Quarterly Report on Form 10-Q for the
fiscal quarter ended June 30, 2000, filed pursuant to Section 13(a) or 15(d) of
the Exchange Act.
The Company's Quarterly Report on Form 10-Q for the
fiscal quarter ended September 30, 2000, filed pursuant to Section 13(a) or
15(d) of the Exchange Act.
The Company's Current Report on Form 8-K, filed with the
Commission on January 27, 2000 pursuant to Section 13(a) or 15(d) of the
Exchange Act.
The description of the Registrant's Common Stock and
associated preferred share purchase rights, contained in the Registrant's
Registration Statement on Form 8-A filed with the Commission on March 24,
1992 and August 8, 1995, registering such shares and associated rights
pursuant to Section 12 of the Exchange Act, including any amendment or
report updating such descriptions.
All documents filed by the Company pursuant to Sections
13(a), 13(c), 14 and 15(d) of the Exchange Act subsequent to the filing of this
Registration Statement, and prior to the filing of a post-effective amendment
that indicates that all securities offered have been sold or that deregisters
all securities then remaining unsold, shall be deemed to be incorporated by
reference in the Registration Statement and to be part hereof from the date of
filing such documents.
Item 4.  Description of Securities.
Not applicable.
Item 5.  Interests of Named Experts and Counsel.
Not applicable.
Item 6.  Indemnification of Directors and Officers.
Section 145 of the Delaware General Corporation Law
authorizes a court to award or a corporation's Board of Directors to grant
indemnification to directors and officers in terms sufficiently broad to permit
such indemnification under certain circumstances for liabilities (including
reimbursement for expenses incurred) arising under the Securities Act of 1933
(the "SECURITIES ACT"), as amended.  The Company has included in its
Certificate of Incorporation a provision that to the fullest extent permitted by
Delaware law, the Company's directors will not be liable for monetary damages
for breach of the directors' fiduciary duty of care to the Company and its
stockholders.  In addition, the Company's Bylaws provide that the Company is
required to indemnify its officers and directors to the fullest extent permitted
by Delaware law, including those circumstances in which indemnification would
otherwise be discretionary, and that the Company is required to advance expenses
to its officers and directors as incurred.  Further, the Company intends to
enter into indemnification agreements with its officers and directors, providing
such individuals indemnification to the maximum extent permitted by the Delaware
General Corporation Law.
Insofar as indemnification for liabilities arising under the
Securities Act may be permitted to directors, officers and controlling persons
of the Company pursuant to the Delaware General Corporation Law, the foregoing
Bylaw provision or any Indemnification Agreement, the Company has been informed
that in the opinion of the Securities and Exchange Commission such
indemnification is against public policy as expressed in the Securities Act and
is therefore unenforceable.
Item 7.  Exemption from Registration Claimed.
Not applicable.
Item 8.  Exhibits.
Exhibit
Number
Description
4.1
2001 Nonstatutory Stock Option Plan.
5.1
Opinion of Wilson Sonsini Goodrich & Rosati,
P.C. as to legality of securities being registered.
23.1
Consent of Wilson Sonsini Goodrich & Rosati,
P.C. (contained in Exhibit 5.1).
23.2
Consent of Ernst & Young LLP, Independent
Auditors.
24.1
Power of Attorney (see page II-4).
Item 9.  Undertakings.
(a)	The undersigned Registrant hereby undertakes:
(1)	To file, during any period in which offers or sales
are being made, a post-effective amendment to this registration statement:
(i)	To include any prospectus required by
section 10(a)(3) of the Securities Act of 1933;
(ii)	To reflect in the prospectus any facts or events
arising after the effective date of the registration statement (or the most
recent post-effective amendment thereof) which, individually or in the
aggregate, represent a fundamental change in the information set forth in the
registration statement.  Notwithstanding the foregoing, any increase or decrease
in volume of securities offered (if the total dollar value of securities offered
would not exceed that which was registered) and any deviation from the low or
high end of the estimated maximum offering range may be reflected in the form of
prospectus filed with the Commission pursuant to Rule 424(b) if, in the
aggregate, the changes in volume and price represent no more than a 20 percent
change in the maximum aggregate offering price set forth in the "Calculation of
Registration Fee" table in the effective registration statement;
(iii)	To include any material information with respect to
the plan of distribution not previously disclosed in the registration statement
or any material change to such information in the registration statement.
Provided
,
however
, that
paragraphs (a)(1)(i) and (a)(1)(ii) do not apply if the information
required to be included in a post-effective amendment by those paragraphs is
contained in periodic reports filed by the Registrant pursuant to
section 13 or section 15(d) of the Securities Exchange Act of 1934
that are incorporated by reference in this registration statement.
(2)	That, for the purpose of determining any liability
under the Securities Act of 1933, each such post-effective amendment shall be
deemed to be a new registration statement relating to the securities offered
therein, and the offering of such securities at that time shall be deemed to be
the initial bona fide offering thereof.
(3)	To remove from registration by means of a post-
effective amendment any of the securities being registered which remain unsold
at the termination of the offering.
(b)	The undersigned Registrant hereby undertakes that, for
purposes of determining any liability under the Securities Act, each filling of
the Registrant's annual report pursuant to Section 13(a) or
Section 15(d) of the Exchange Act (and, where applicable, each filing of an
employee benefit plan's annual report pursuant to Section 15(d) of the
Exchange Act) that is incorporated by reference in the Registration Statement
shall be deemed to be a new registration statement relating to the securities
offered therein, and the offering of such securities at that time shall be
deemed to be an initial bona fide offering thereof.
(c)	Insofar as indemnification for liabilities arising
under the Securities Act may be permitted to directors, officers and controlling
persons of the Registrant pursuant to the Delaware General Corporation Law, the
Certificate of Incorporation of the Registrant, the Bylaws of the Registrant,
Indemnification Agreements entered into between the Registrant and its officers
and directors, or otherwise, the Registrant has been advised that in the opinion
of the Securities and Exchange Commission such indemnification is against public
policy as expressed in the Securities Act and is, therefore, unenforceable.  In
the event that a claim for indemnification against such liabilities (other than
the payment by the Registrant of expenses incurred or paid by a director,
officer or controlling person of the Registrant in the successful defense of any
action, suit or proceeding) is asserted by such director, officer or controlling
person in connection with the securities being registered, the Registrant will,
unless in the opinion of its counsel the matter has been settled by controlling
precedent, submit to a court of appropriate jurisdiction the question whether
such indemnification by it is against public policy as expressed in the
Securities Act and will be governed by the final adjudication of such issue.
SIGNATURES
Pursuant to the requirements of the Securities Act of
1933, the Registrant certifies that it has reasonable grounds to believe that it
meets all of the requirements for filing on Form S-8 and has duly caused
this Registration Statement to be signed on its behalf by the undersigned,
thereunto duly authorized, in the City of Foster City, State of California, on
this 25th day of January, 2001.
CELL GENESYS, INC.
By:
/s/ Matt Pfeffer
Matt Pfeffer
Chief Financial Officer
POWER OF ATTORNEY
KNOW ALL PERSONS BY THESE PRESENTS, that each person
whose signature appears below hereby constitutes and appoints, Matt Pfeffer, or
his attorney-in-fact, for him in any and all capacities, to sign any and all
amendments to this Registration Statement on Form S-8, and to file the same,
with exhibits thereto and other documents in connection therewith, with the
Securities and Exchange Commission, hereby ratifying and confirming all that
said attorney-in-fact, or his substitute may do or cause to be done by virtue
hereof.
Pursuant to the requirements of the Securities Act of 1933,
this Registration Statement has been signed below by the following persons in
the capacities and on the dates indicated.
Signature
Title
Date
/s/ Stephen A. Sherwin, M.D.
Stephen A. Sherwin, M.D.
Chairman of the Board, President, and Chief Executive Officer
(Principal Executive Officer)
January 25, 2001
/s/  Matt Pfeffer
Matt Pfeffer
Chief Financial Officer (Principal Financial and Accounting
Officer)
January 25, 2001
/s/ David W. Carter
David W. Carter
Director
January 25, 2001
/s/  James M. Gower
James M. Gower
Director
January 25, 2001
/s/ John T. Potts, Jr., M.D.
John T. Potts, Jr., M.D.
Director
January 25, 2001
/s/  Eugene L. Step
Eugene L. Step
Director
January 25, 2001
/s/ Inder M. Verma, Ph.D.
Inder M. Verma, Ph.D.
Director
January 25, 2001
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
EXHIBITS
Registration Statement on Form S-8
CELL GENESYS, INC.
INDEX TO EXHIBITS
Exhibit
Number
Description
4.1
2001 Nonstatutory Stock Option Plan.
5.1
Opinion of Wilson Sonsini Goodrich & Rosati,
P.C. as to legality of securities being registered.
23.1
Consent of Wilson Sonsini Goodrich & Rosati,
P.C. (contained in Exhibit 5.1).
23.2
Consent of Ernst & Young LLP, Independent
Auditors.
24.1
Power of Attorney (see page II-4).