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<p align="center"><b><font size="2">As filed with the Securities and
Exchange Commission on November 26, 2002<br>
Registration
No. 333-______</font></b></p>

<hr color="#000000">

<p align=center>&nbsp;</p>

<p align=center><b>UNITED STATES<br>
SECURITIES AND
EXCHANGE COMMISSION<br>
Washington, D.C. 20549<br>
______________&nbsp;</b></p>

<p align=center><b>FORM S-8</b></p>

<p align=center><b>REGISTRATION STATEMENT<br>
UNDER THE SECURITIES ACT OF 1933</b></p>

<p align=center><u>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</u></p>

<p align=center><b>IMCLONE
SYSTEMS INCORPORATED<br>
</b>(Exact name of
registrant as specified in its charter)</p>

<p align=center>&nbsp;</p>

<div align="left">

<table border=0 cellspacing=0 cellpadding=0 width="780" style="border-collapse: collapse" bordercolor="#111111">
 <tr>
  <td width=308 valign=top align="center">
  <p align=center><b>DELAWARE</b></p>
  </td>
  <td width=318 valign=top align="center">
  <p align=center><b>&nbsp;</b></p>
  </td>
  <td width=150 valign=top align="center">
  <p align=center><b>04-2834797</b></p>
  </td>
 </tr>
 <tr>
  <td width=308 valign=top align="center">
  <p align="center">(State or other jurisdiction
  of <br>
  incorporation or
  organization)</p>
  </td>
  <td width=318 valign=top align="center">

  </td>
  <td width=150 valign=top align="center">

  (I.R.S. Employer <br>
  Identification No.)</td>
 </tr>
 <tr>
  <td width=308 valign=top align="center">
  <p>&nbsp;</p>
  </td>
  <td width=318 valign=top align="center">

  </td>
  <td width=150 valign=top align="center">

  </td>
 </tr>
 <tr>
  <td width=308 valign=top align="center">

  </td>
  <td width=318 valign=top align="center">
  <p>&nbsp;&nbsp;</p>
  </td>
  <td width=150 valign=top align="center">

  </td>
 </tr>
 <tr>
  <td width=308 valign=top align="center">

  </td>
  <td width=318 valign=top align="center">
  <p align="center">&nbsp; <b>180 Varick Street<br>
  New York, New York<br>
  </b>(Address of
  Principal Executive Offices)</p>
  </td>
  <td width=150 valign=top align="center">

  <b><br>
  10014<br>
  </b>(Zip Code)</td>
 </tr>
 <tr>
  <td width=308 valign=top>
  <p align=center>&nbsp;</p>
  </td>
  <td width=318 valign=top>
  <p align=center>&nbsp;</p>
  </td>
  <td width=150 valign=top align="center">
  <p align=center>&nbsp;</p>
  </td>
 </tr>
</table>

</div>

<p align=center>______________</p>

<p align=center><b>&nbsp;</b></p>

<p align=center><b>IMCLONE
SYSTEMS INCORPORATED<br>
2002
STOCK OPTION PLAN<br>
</b>(Full title of the
plan)<br>
______________</p>

<p align=center><b>&nbsp;</b></p>

<p align=center><b>Catherine M. Vaczy,
Esq.<br>
Vice President, Legal
and <br>
Associate General
Counsel<br>
180 Varick Street<br>
New York, New York&nbsp; 10014<br>
</b>(Name and address of agent for service)</p>

<p align=center><b>(212) 645-1405<br>
</b>(Telephone number, including area code, of agent for
service)</p>

<p align=center><b>CALCULATION OF REGISTRATION FEE</b></p>

<table border=1 cellspacing=0 cellpadding=0 width="696">
 <tr>
  <td valign=top width="146">
  <p><b>Title of each class<br>
  of securities<br>
  to be registered</b></p>
  </td>
  <td valign=top width="138">
  <p><b>Amount to be<br>
  registered (1)</b></p>
  </td>
  <td valign=top width="122">
  <p><b>Proposed<br>
  maximum<br>
  offering price<br>
  per share (2)</b></p>
  </td>
  <td valign=top width="139">
  <p><b>Proposed<br>
  maximum<br>
  aggregate<br>
  offering price (2)</b></p>
  <p><b>&nbsp;</b></p>
  </td>
  <td valign=top width="139">
  <p><b>Amount of<br>
  registration<br>
  fee</b></p>
  </td>
 </tr>
 <tr>
  <td width=146 valign=top>
  <p>Common Stock, par value
  $.001 per share.......................</p>
  </td>
  <td width=138 valign=top>

  <p align="center">&nbsp;&nbsp; 3,300,000 shares</p>
  </td>
  <td width=122 valign=top>
  <p align="center">$12.10</p>
  </td>
  <td width=139 valign=top>
  <p align="center">$39,930,000</p>
  </td>
  <td width=139 valign=top>
  <p align="center">$3,673.56</p>
  </td>
 </tr>
</table>



<p>&nbsp;</p>



<hr color="#000080"><p style="page-break-after: always"></p>



<p>&nbsp;</p>



<p>&nbsp;</p>



<p>(1)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Plus an indeterminate number of
additional shares which may be offered and issued to prevent dilution resulting<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; from stock splits, stock
dividends or similar transactions.</p>



<p align="justify">(2)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Estimated pursuant to Rule 457(c)
under the Securities Act of 1933, as amended, solely for the purpose of <br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp; computing the registration fee, based on
the average of the high ($13.44) and low ($10.76) prices of the securities<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp; being registered hereby on the Nasdaq
National Market on November 19, 2002.</p>





<p align=center><b>PART I&nbsp;</b></p>

<p align="center"><b>INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS</b></p>
<p align="justify">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The documents containing the information specified in Part I of this registration statement on Form S-8 (the &quot;Registration Statement&quot;) will be sent or given to participants in the ImClone Systems Incorporated 2002 Stock Option Plan (the &quot;Plan&quot;) as specified under Rule 428(b)(i) under the Securities Act of 1933, as amended (the &quot;Securities Act&quot;). &nbsp;Such documents are not required to be, and are not being, filed by ImClone Systems Incorporated, a Delaware corporation (the &quot;Company&quot;), with the Securities and Exchange Commission (the &quot;Commission&quot;) either as part of this Registration Statement or as prospectuses or prospectus supplements pursuant to Rule 424 under the Securities Act. &nbsp;Such documents, together with the documents incorporated by reference herein pursuant to Item 3 of Part II of this Registration Statement, constitute a prospectus that meets the requirements of Section 10(a) of the Securities Act.</p>



<p><b>ITEM 1.&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; PLAN
INFORMATION.*</b></p>



<p><b>ITEM 2.&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; REGISTRANT
INFORMATION AND EMPLOYEE PLAN ANNUAL INFORMATION.*</b></p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; *&nbsp; Information required by Part I to be
contained in the Section 10(a) prospectus is omitted from this Registration
Statement in accordance with Rule 428 under the Securities Act and the Note to
Part I of Form S-8.</p>



<p align=center><b>PART II</b></p>

<p align=center><b>&nbsp;INFORMATION REQUIRED IN
THE REGISTRATION STATEMENT</b></p>

<p><b>ITEM 3.&nbsp; INCORPORATION OF DOCUMENTS BY REFERENCE.</b></p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The following documents, which have heretofore been
filed by the Company with the Commission pursuant to the Securities Exchange
Act of 1934, as amended (the &quot;Exchange Act&quot;), are incorporated by reference
herein and shall be deemed to be a part hereof:</p>



<blockquote>
  <blockquote>



<p align="justify">(a)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The Company's Annual
Report on Form 10-K for the fiscal year ended  December
31, 2001;</p>

<p align="justify">(b)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; All reports filed
pursuant to Section 13(a) or 15(d) of the Exchange Act since  December 31, 2001, including the Company's
Quarterly Reports on Form 10-Q for
the fiscal quarters ended March 31, 2002, June 30, 2002 and September 30,  2002, three Current Reports on Form 8-K
dated January 25, 2002 and Current  Reports
on Form 8-K dated February 19, 2002, March 6, 2002, June 26, 2002 &nbsp;and November 18, 2002; and</p>

<p>&nbsp;</p>

<p>&nbsp;</p>

  </blockquote>
</blockquote>
<hr color="#000080"><p style="page-break-after: always"></p>

<p>&nbsp;</p>

<blockquote>
  <blockquote>

<p align="justify">(c)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The description of the
Company's Common Stock, par value $.001 per share, contained in the Company's Registration Statement on Form 8-A filed
under the  Exchange Act on
October 23, 1991, including any amendment or report filed  for the purpose of updating such description.</p>

  </blockquote>
</blockquote>

<p align="justify">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; All other documents filed by the Company with the
Commission pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act
subsequent to the date of this Registration Statement and prior to the filing
of a post-effective amendment which indicates that all securities offered
herein have been sold or which de-registers all securities then remaining
unsold, shall be deemed to be incorporated by reference in this Registration
Statement and to be a part hereof from the date of filing of such documents
(such documents, and the documents enumerated above, being hereinafter referred
to collectively as the &quot;Incorporated Documents&quot;).</p>



<p align="justify">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Any statement contained in an Incorporated Document
shall be deemed to be modified or superseded for purposes of this Registration
Statement to the extent that a statement contained therein or in any other
subsequently filed Incorporated Document modifies or supersedes such
statement.&nbsp; Any such statements so
modified or superseded shall not be deemed, except as so modified or
superseded, to constitute a part of this Registration Statement.</p>



<p><b>ITEM 4.&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; DESCRIPTION OF SECURITIES.</b></p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Not applicable.</p>



<p><b>ITEM 5.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; INTERESTS
OF NAMED EXPERTS AND COUNSEL.</b></p>

<p align="justify">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Certain legal matters with respect to the offering of
the shares of Company Common Stock registered hereby have been passed upon by
Catherine M. Vaczy, Vice President, Legal and Associate General Counsel of the
Company.&nbsp; Ms. Vaczy owns Company Common
Stock and holds employee stock options to purchase Company Common Stock.</p>



<p><b>ITEM
6.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; INDEMNIFICATION OF DIRECTORS
AND OFFICERS.</b></p>

<p align="justify">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The Company's Certificate of Incorporation and Bylaws set forth the
extent to which officers and directors of the Company may be indemnified
against any liabilities which they may incur.&nbsp;
The general effect of such provisions is that, on the terms and
conditions set forth in the Company's Certificate of Incorporation and Bylaws, any person made a party or
threatened to be made a party to an action, suit or proceeding by reason of the
fact that he or she is or was a director, officer or employee of the Company,
or is or was serving as a director, officer, employee or agent of another
corporation or other enterprise at the request of the Company, shall be
indemnified by the Company against expenses (including attorneys' fees,
judgments, fines and amounts paid in settlement) reasonably incurred or
suffered by him or her in connection with such action, suit or proceeding, to
the full extent permitted under the laws of the State of Delaware; provided,
however, that, subject to certain limited exceptions, the Company shall
indemnify any such person seeking indemnification in connection with a
proceeding initiated by such person only if such proceeding was authorized by
the Board of Directors of the Company.&nbsp;
The Company's Certificate of Incorporation gives the Board of Directors
of the Company the authority to extend such indemnification to employees and
other agents of the Company as well.</p>

<p align="justify">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The general effect of the indemnification provisions contained in Section 145 of the General Corporation Law of the State of Delaware (the &quot;DGCL&quot;) is as follows:&nbsp; A director or officer who, by reason of such directorship or officership,</p>
<p>&nbsp;</p>
<hr color="#000080"><p style="page-break-after: always"></p>
<p>&nbsp;</p><p align="justify">is involved in any action, suit or proceeding (other than an action by or in the right of the corporation) shall be indemnified by the corporation against expenses (including attorneys' fees), judgments, fines and amounts paid in settlement actually and reasonably incurred by him or her in connection with such action, suit or proceeding if he or she acted in good faith and in a manner he or she reasonably believed to be in or not opposed to the best interests of the corporation, and, with respect to any criminal action or proceeding, has no reasonable cause to believe that his or her conduct was unlawful.&nbsp; A director or officer who, by reason of such directorship or officership, is involved in any action or suit by or in the right of the corporation shall be indemnified by the corporation against expenses (including attorneys' fees) actually and reasonably incurred by him or her in connection with the defense or settlement of such action or suit if he or she acted in good faith and in a manner he or she reasonably believed to be in or not opposed to the best interests of the corporation, except that no indemnification shall be made in respect of any claim, issue or matter as to which he or she shall have been adjudged to be liable to the corporation unless and only to the extent that a court of appropriate jurisdiction shall approve such indemnification.</p>
<p align="justify">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The Company's Certificate of Incorporation provides that, to the maximum extent permitted under the DGCL, a director of the Company shall not be personally liable to the Company or to any of its stockholders for monetary damages for breach of fiduciary duty as a director of the Company.&nbsp; Section 102(b)(7) of the DGCL permits a corporation to include in its certificate of incorporation a provision that eliminates or limits the personal liability of a director to the corporation or its stockholders for monetary damages for breach of fiduciary duty as a director; provided, that such provision shall not eliminate or limit the liability of a director (i) for any breach of the director's duty of loyalty to the corporation or its stockholders, (ii) for acts or omissions not in good faith or which involve intentional misconduct or a knowing violation of law, (iii)
for unlawful payments of dividends or unlawful stock repurchases, redemptions or
other distributions, or (iv) for any transaction from which the director derived an improper personal benefit.</p>



<p align="justify">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
The Company maintains standard policies of insurance under which coverage is
provided (a) to its directors and officers against loss arising from claims made
by reason of breach of duty or other wrongful act, and (b) to the Company with
respect to payments which may be made by the Company to such officers and
directors pursuant to the above indemnification provision or otherwise as a
matter of law.</p>



<p align="justify">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The Company has entered into Employment Agreements with Harlan
W. Waksal, Daniel S. Lynch and S. Joseph Tarnowski pursuant to which the
Company has agreed to advance expenses for the defense of and to indemnify such
persons to the fullest extent permitted by Delaware law.</p>



<p><b>ITEM 7.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; EXEMPTION
FROM REGISTRATION CLAIMED. </b> </p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Not applicable. </p>



<p><b>ITEM 8.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; EXHIBITS.
</b>
</p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <b><u>Exhibit No.</u></b>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <b><u>Exhibit</u></b></p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 4.1&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Certificate of Incorporation of the
Company, as amended through December 31,<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 1998 (filed as Exhibit 3.2 to the
Company's Quarterly Report on Form 10-Q for<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; the quarter ended June 30, 1997).*</p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 4.2&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Amendment dated June 4, 1999 to the
Company's Certificate of Incorporation,<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; as amended (filed as Exhibit 3.1A to
the Company' Quarterly Report on Form <br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 10-Q for the quarter ended June 30, 1999).*</p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 4.3&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Amendment dated June 12, 2000 to
the Company's Certificate of Incorporation,<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; as amended (filed as Exhibit 3.1A
to the Company' Quarterly Report on Form <br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 10-Q for the quarter ended June 30,
2000).*</p>



<p>&nbsp;</p>



<hr color="#000080"><p style="page-break-after: always"></p>



<p>&nbsp;</p>



<p>&nbsp;</p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 4.4&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Amendment dated August 9, 2002 to
the Company's Certificate of Incorporation,<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; as amended (filed as Exhibit 3.1C
to the Company' Quarterly Report on Form <br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 10-Q for the quarter ended June 30,
2002).*</p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 4.5&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Amended and Restated Bylaws of the
Company (filed as Exhibit 3.2 to the <br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Company's Current Report on Form 8-K dated
January 21, 1998).*</p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 5.1&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Opinion of Catherine M. Vaczy, Esq.</p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 23.1&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Consent of KPMG LLP.</p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 23.2&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Consent of Catherine M. Vaczy, Esq.
(included in Exhibit 5.1).</p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 24.1&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Power of Attorney (included on
signature pages to this Registration Statement).</p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 99.1&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; ImClone Systems Incorporated 2002
Stock Option Plan (filed as Appendix A to<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; the definitive Proxy Statement for
the 2002 Annual Meeting of Stockholders, filed <br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; on April 24, 2002).*<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; -------------------------------------------<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; *&nbsp; Incorporated herein by reference</p>

<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </p>

<p><b>ITEM 9.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; UNDERTAKINGS.
</b>
</p>



<blockquote>
  <blockquote>



<p>(a)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The
undersigned hereby undertakes: </p>



    <blockquote>



<p align="justify">(1)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; To file, during any period in which
offers or sales are being made, a post-effective amendment to this Registration
Statement: </p>



      <blockquote>



<p align="justify">(i)&nbsp;&nbsp; To include any prospectus required by Section
10(a)(3) of the Securities Act; </p>

<p align="justify">(ii)&nbsp; To reflect in the prospectus any facts or
events arising after the effective date of this Registration Statement (or the
most recent post-effective amendment thereof) which, individually or in the
aggregate, represent a fundamental change in the information set forth in this
Registration Statement.&nbsp; Notwithstanding
the foregoing, any increase or decrease in volume of securities offered (if the
total dollar value of securities offered would not exceed that which was
registered) and any deviation from the low or high end of the estimated maximum
offering range may be reflected in the form of prospectus filed with the
Commission pursuant to Rule 424(b) if, in the aggregate, the changes in volume
and price represent no more than a 20% change in the maximum aggregate offering
price set forth in the &quot;Calculation of Registration Fee&quot; table in the effective
Registration Statement; and</p>

<p align="justify">(iii)To include
any material information with respect to the plan of distribution not
previously disclosed in this Registration Statement or any material change to
such information in this Registration Statement;</p>

      </blockquote>
    </blockquote>
  </blockquote>
</blockquote>

<p><u>provided</u>, <u>however</u>, that paragraphs
(a)(1)(i) and (a)(1)(ii) above do not apply if the registration statement is on
Form S-3, Form S-8 or Form F-3, and the information required to be included in
a post-effective amendment by those paragraphs is contained in periodic reports
filed by the registrant pursuant to Section 13 or Section 15(d) of the Exchange
Act that are incorporated by reference in the registration statement. </p>



<p>&nbsp;</p>



<hr color="#000080"><p style="page-break-after: always"></p>

<p>&nbsp;</p>



<p>&nbsp;</p>



<blockquote>
  <blockquote>
    <blockquote>



<p align="justify">(2)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; That,
for the purpose of determining any liability under the Securities Act, each
such post-effective amendment shall be deemed to be a new registration
statement relating to the securities offered therein, and the offering of such
securities at that time shall be deemed to be the initial bona fide offering
thereof; and </p>



<p align="justify">(3)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; To
remove from registration by means of a post-effective amendment any of the
securities being registered which remain unsold at the termination of the
offering. </p>



    </blockquote>



<p align="justify">(b)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The
undersigned registrant hereby undertakes that, for purposes of determining any
liability under the Securities Act, each filing of the registrant's Annual
Report pursuant to Section 13(a) or Section 15(d) of the Exchange Act (and,
where applicable, each filing of an employee benefit plan's Annual Report pursuant
to Section 15(d) of the Exchange Act) that is incorporated by reference in the
registration statement shall be deemed to be a new registration statement
relating to the securities offered therein, and the offering of such securities
at that time shall be deemed to be the initial bona fide offering thereof.</p>



<p align="justify">(c)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Insofar
as indemnification for liabilities arising under the Securities Act may be
permitted to directors, officers and controlling persons of the registrant
pursuant to the foregoing provisions, or otherwise, the registrant has been
advised that in the opinion of the Commission such indemnification is against
public policy as expressed in the Securities Act and is, therefore,
unenforceable.&nbsp; In the event that a claim
for indemnification against such liabilities (other than the payment by the
registrant of expenses incurred or paid by a director, officer or controlling
person of the registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the registrant will, unless in
the opinion of its counsel the matter has been settled by controlling
precedent, submit to a court of appropriate jurisdiction the question whether
such indemnification by it is against public policy as expressed in the Securities
Act and will be governed by the final adjudication of such issue. </p>

  </blockquote>
</blockquote>

<br
clear=all>




<hr color="#000080"><p style="page-break-after: always"></p>
<p>&nbsp;</p>
<p>&nbsp;</p>




<p align=center><b>SIGNATURES</b></p>



<p align="justify">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Pursuant to the requirements of the Securities Act of
1933, as amended, the Registrant certifies that it has reasonable grounds to
believe that it meets all of the requirements for filing on Form S-8 and has
duly caused this Registration Statement to be signed on its behalf by the
undersigned, thereunto duly authorized, in the City of New York, State of New
York, on the 26th day of November, 2002.</p>



<table border=0 cellspacing=0 cellpadding=0 width="686" style="border-collapse: collapse" bordercolor="#111111">
 <tr>
  <td width=226 valign=top>

  </td>
  <td width=123 valign=top>
  <p>&nbsp;</p>
  </td>
  <td width=329 valign=top>

  IMCLONE SYSTEMS INCORPORATED</td>
 </tr>
 <tr>
  <td width=226 valign=top>

  </td>
  <td width=123 valign=top>

  </td>
  <td width=329 valign=top>

  &nbsp;</td>
 </tr>
 <tr>
  <td width=226 valign=top>

  </td>
  <td width=123 valign=top>

  </td>
  <td width=329 valign=top>

  &nbsp;</td>
 </tr>
 <tr>
  <td width=226 valign=top>

  </td>
  <td width=123 valign=top>

  </td>
  <td width=329 valign=top>

  </td>
 </tr>
 <tr>
  <td width=226 valign=top>

  </td>
  <td width=123 valign=top>
  <p align="right">&nbsp;</p>
  </td>
  <td width=329 valign=top>
  <p>By:&nbsp;&nbsp; <u>/s/Harlan W. Waksal</u></p>
  </td>
 </tr>
 <tr>
  <td width=226 valign=top>
  <p>&nbsp;</p>
  </td>
  <td width=123 valign=top>

  </td>
  <td width=329 valign=top>

  &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Harlan W. Waksal</td>
 </tr>
 <tr>
  <td width=226 valign=top>
  <p>&nbsp;</p>
  </td>
  <td width=123 valign=top>

  </td>
  <td width=329 valign=top>

  &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; President
  and Chief Executive Officer</td>
 </tr>
 <tr>
  <td width=226 valign=top>

  </td>
  <td width=123 valign=top>

  </td>
  <td width=329 valign=top>

  </td>
 </tr>
</table>



<p align=center>&nbsp;</p>



<p align=center><b>POWER OF ATTORNEY</b></p>



<p align="justify">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Pursuant to the requirements of the
Securities Act of 1933, as amended, this Registration Statement has been signed
below by the following persons in the capacities indicated on November 26, 2002.
&nbsp;Each person whose individual signature
appears below hereby authorizes Harlan W. Waksal, Daniel S. Lynch and Clifford R.
Saffron, or any of them, to execute in the name and on behalf of each such
person and to file any amendment to this Registration Statement, and appoints
Harlan W. Waksal, Daniel S. Lynch and Clifford R. Saffron, or any of them, as
attorney-in-fact to sign on his behalf individually and in each capacity stated
below, and to file any amendments to this Registration Statement, including any
and all post-effective amendments.</p>





<p align="justify">&nbsp;</p>





<div align="left">





<table border=0 cellspacing=0 cellpadding=0 width="704" style="border-collapse: collapse" bordercolor="#111111">
 <tr>
  <td valign=top>
  <p><u>/s/Robert F. Goldhammer&nbsp;&nbsp; </u></p>
  </td>
  <td valign=top>

  Chairman
  of the Board of Directors</td>
  <td width=2 valign=top>

  </td>
 </tr>
 <tr>
  <td valign=top>
  <p>Robert F. Goldhammer</p>
  </td>
  <td valign=top>

  </td>
  <td width=2 valign=top>

  </td>
 </tr>
 <tr>
  <td valign=top>

  &nbsp;</td>
  <td valign=top>

  </td>
  <td width=2 valign=top>

  </td>
 </tr>
 <tr>
  <td valign=top>
  <p><u>/s/Harlan W. Waksal&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </u><br>
  Harlan W. Waksal</p>
  </td>
  <td valign=top>

  President, Chief Executive Officer and Director<br>
  (Principal
  Executive Officer)</td>
  <td width=2 valign=top>
  <p></p>
  </td>
 </tr>
 <tr>
  <td valign=top>

  &nbsp;</td>
  <td valign=top>

  </td>
  <td width=2 valign=top>

  </td>
 </tr>
 <tr>
  <td valign=top>
  <p><u>/s/Daniel S.
  Lynch&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </u><br>
  Daniel S.
  Lynch</p>
  </td>
  <td valign=top>
  <p>Senior
  Vice President, Finance and Chief <br>
  Financial
  Officer (Principal Financial Officer)</p>
  </td>
  <td width=2 valign=top>

  </td>
 </tr>
 <tr>
  <td valign=top>
  <p>&nbsp;</p>
  </td>
  <td valign=top>
  <p>&nbsp;</p>
  </td>
  <td width=2 valign=top>

  </td>
 </tr>
 <tr>
  <td valign=top>

  </td>
  <td valign=top>

  </td>
  <td width=2 valign=top>

  </td>
 </tr>
 <tr>
  <td valign=top>
  <p><u>/s/Andrew G. Bodnar&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </u></p>
  </td>
  <td valign=top>
  <p>Director</p>
  </td>
  <td width=2 valign=top>

  </td>
 </tr>
 <tr>
  <td valign=top>
  <p>Andrew G. Bodnar</p>
  </td>
  <td valign=top>

  </td>
  <td width=2 valign=top>

  </td>
 </tr>
 <tr>
  <td valign=top>

  &nbsp;</td>
  <td valign=top>

  </td>
  <td width=2 valign=top>

  </td>
 </tr>
 <tr>
  <td valign=top>
  <p><u>/s/Vincent T.
  DeVita, Jr.&nbsp;&nbsp;&nbsp;&nbsp; </u></p>
  </td>
  <td valign=top>
  <p>Director</p>
  </td>
  <td width=2 valign=top>

  </td>
 </tr>
 <tr>
  <td valign=top>
  <p>Vincent T.
  DeVita, Jr.</p>
  </td>
  <td valign=top>

  </td>
  <td width=2 valign=top>

  </td>
 </tr>
 <tr>
  <td valign=top>

  &nbsp;</td>
  <td valign=top>

  </td>
  <td width=2 valign=top>

  </td>
 </tr>
 <tr>
  <td valign=top>
  <p><u>/s/David M. Kies&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </u></p>
  </td>
  <td valign=top>
  <p>Director</p>
  </td>
  <td width=2 valign=top>

  </td>
 </tr>
 <tr>
  <td valign=top>
  <p>David M. Kies</p>
  </td>
  <td valign=top>

  </td>
  <td width=2 valign=top>

  </td>
 </tr>
 <tr>
  <td valign=top>

  &nbsp;</td>
  <td valign=top>

  </td>
  <td width=2 valign=top>

  </td>
 </tr>
 <tr>
  <td valign=top>
  <p><u>/s/Paul B. Kopperl&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </u></p>
  </td>
  <td valign=top>
  <p>Director</p>
  </td>
  <td width=2 valign=top>

  </td>
 </tr>
 <tr>
  <td valign=top>
  <p>Paul B. Kopperl</p>
  </td>
  <td valign=top>

  </td>
  <td width=2 valign=top>

  </td>
 </tr>
 <tr>
  <td valign=top>

  &nbsp;</td>
  <td valign=top>

  </td>
  <td width=2 valign=top>

  </td>
 </tr>
 </table>



</div>



<b><br clear=all>
</b>

<hr color="#000080"><p style="page-break-after: always"></p>
<p>&nbsp;</p>





<table border=0 cellspacing=0 cellpadding=0 width="700" style="border-collapse: collapse" bordercolor="#111111">
 <tr>
  <td width=175 valign=top>
  <p>&nbsp;</p>
  </td>
  <td width=301 valign=top>
  <p>&nbsp;</p>
  </td>
 </tr>
 <tr>
  <td width=175 valign=top>
  <p>&nbsp;</p>
  </td>
  <td width=301 valign=top>
  <p>&nbsp;</p>
  </td>
 </tr>
 <tr>
  <td width=175 valign=top>
  <p><u>/s/Arnold J.
  Levine&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </u></p>
  </td>
  <td width=301 valign=top>
  <p>Director</p>
  </td>
 </tr>
 <tr>
  <td width=175 valign=top>
  <p>Arnold J.
  Levine</p>
  </td>
  <td width=301 valign=top>

  </td>
 </tr>
 <tr>
  <td width=175 valign=top>

  &nbsp;</td>
  <td width=301 valign=top>

  </td>
 </tr>
 <tr>
  <td width=175 valign=top>
  <p><u>/s/John Mendelsohn&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </u></p>
  </td>
  <td width=301 valign=top>
  <p>Director</p>
  </td>
 </tr>
 <tr>
  <td width=175 valign=top>
  <p>John Mendelsohn</p>
  </td>
  <td width=301 valign=top>

  </td>
 </tr>
 <tr>
  <td width=175 valign=top>

  &nbsp;</td>
  <td width=301 valign=top>

  </td>
 </tr>
 <tr>
  <td width=175 valign=top>
  <p><u>/s/William R.
  Miller&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </u></p>
  </td>
  <td width=301 valign=top>
  <p>Director</p>
  </td>
 </tr>
 <tr>
  <td width=175 valign=top>
  <p>William R.
  Miller</p>
  </td>
  <td width=301 valign=top>

  </td>
 </tr>
 <tr>
  <td width=175 valign=top>

  &nbsp;</td>
  <td width=301 valign=top>

  </td>
 </tr>
 <tr>
  <td width=175 valign=top>
  <p><u>/s/Peter S. Ringrose&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </u></p>
  </td>
  <td width=301 valign=top>
  <p>Director</p>
  </td>
 </tr>
 <tr>
  <td width=175 valign=top>
  <p>Peter S. Ringrose</p>
  </td>
  <td width=301 valign=top>

  </td>
 </tr>
</table>



<p>&nbsp;</p>
<hr color="#000080"><p style="page-break-after: always"></p>
<p>&nbsp;</p>
<p>&nbsp;</p>

<p align=center><b>EXHIBIT INDEX</b></p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </p>

<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <b><u>Exhibit<br>
</u>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <u>Number</u>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;<u>Description</u></b></p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 4.1&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Certificate of Incorporation of the
Company, as amended through December 31,<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 1998 (filed as Exhibit 3.2 to the
Company's Quarterly Report on Form 10-Q for<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; the quarter ended June 30, 1997).*</p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 4.2&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Amendment dated June 4, 1999 to the
Company's Certificate of Incorporation,<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; as amended (filed as Exhibit 3.1A to
the Company' Quarterly Report on Form <br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 10-Q for the quarter ended June 30,
1999).*</p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 4.3&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Amendment dated June 12, 2000 to
the Company's Certificate of Incorporation,<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; as amended (filed as Exhibit 3.1A
to the Company' Quarterly Report on Form <br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 10-Q for the quarter ended June 30,
2000).*</p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 4.4&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Amendment dated August 9, 2002 to
the Company's Certificate of Incorporation,<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; as amended (filed as Exhibit 3.1C
to the Company' Quarterly Report on Form <br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 10-Q for the quarter ended June 30,
2002).*</p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 4.5&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Amended and Restated Bylaws of the
Company (filed as Exhibit 3.2 to the <br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Company's Current Report on Form 8-K dated
January 21, 1998).*</p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 5.1&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Opinion of Catherine M. Vaczy, Esq.</p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 23.1&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Consent of KPMG LLP.</p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 23.2&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Consent of Catherine M. Vaczy, Esq.
(included in Exhibit 5.1 to this Registration Statement).</p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 24.1&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Power of Attorney (included on
signature pages to this Registration Statement).</p>



<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 99.1&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; ImClone Systems Incorporated 2002
Stock Option Plan (filed as Appendix A<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; to the definitive Proxy Statement for
the 2002 Annual Meeting of Stockholders,<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; filed on April 24, 2002).*<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; -------------------------------------------<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; *&nbsp; Incorporated herein by reference</p>

<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </p><br
clear=all>


&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</body></html>
[{"type": "S-8", "sequence": "1", "filename": "s81.htm", "description": "S-8 FILING", "secsgml_size_bytes": 44813}]
{"company-data": {"conformed-name": "IMCLONE SYSTEMS INC/DE", "cik": "0000765258", "assigned-sic": "2836", "irs-number": "042834797", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-101492", "film-number": "02841350"}, "business-address": {"street1": "180 VARICK ST", "city": "NEW YORK", "state": "NY", "zip": "10014", "phone": "2126451405"}, "mail-address": {"street1": "180 VARICK ST", "city": "NEW YORK", "state": "NY", "zip": "10014"}}
Prepared by E-Services, LLC - www.edgar2.net
As filed with the Securities and
Exchange Commission on November 26, 2002
Registration
No. 333-______
UNITED STATES
SECURITIES AND
EXCHANGE COMMISSION
Washington, D.C. 20549
______________
FORM S-8
REGISTRATION STATEMENT
UNDER THE SECURITIES ACT OF 1933
IMCLONE
SYSTEMS INCORPORATED
(Exact name of
registrant as specified in its charter)
DELAWARE
04-2834797
(State or other jurisdiction
  of
incorporation or
  organization)
(I.R.S. Employer
Identification No.)
180 Varick Street
New York, New York
(Address of
  Principal Executive Offices)
10014
(Zip Code)
______________
IMCLONE
SYSTEMS INCORPORATED
2002
STOCK OPTION PLAN
(Full title of the
plan)
______________
Catherine M. Vaczy,
Esq.
Vice President, Legal
and
Associate General
Counsel
180 Varick Street
New York, New York  10014
(Name and address of agent for service)
(212) 645-1405
(Telephone number, including area code, of agent for
service)
CALCULATION OF REGISTRATION FEE
Title of each class
of securities
to be registered
Amount to be
registered (1)
Proposed
maximum
offering price
per share (2)
Proposed
maximum
aggregate
offering price (2)
Amount of
registration
fee
Common Stock, par value
  $.001 per share.......................
3,300,000 shares
$12.10
$39,930,000
$3,673.56
(1)           Plus an indeterminate number of
additional shares which may be offered and issued to prevent dilution resulting
from stock splits, stock
dividends or similar transactions.
(2)           Estimated pursuant to Rule 457(c)
under the Securities Act of 1933, as amended, solely for the purpose of
computing the registration fee, based on
the average of the high ($13.44) and low ($10.76) prices of the securities
being registered hereby on the Nasdaq
National Market on November 19, 2002.
PART I
INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS
The documents containing the information specified in Part I of this registration statement on Form S-8 (the "Registration Statement") will be sent or given to participants in the ImClone Systems Incorporated 2002 Stock Option Plan (the "Plan") as specified under Rule 428(b)(i) under the Securities Act of 1933, as amended (the "Securities Act").  Such documents are not required to be, and are not being, filed by ImClone Systems Incorporated, a Delaware corporation (the "Company"), with the Securities and Exchange Commission (the "Commission") either as part of this Registration Statement or as prospectuses or prospectus supplements pursuant to Rule 424 under the Securities Act.  Such documents, together with the documents incorporated by reference herein pursuant to Item 3 of Part II of this Registration Statement, constitute a prospectus that meets the requirements of Section 10(a) of the Securities Act.
ITEM 1.          PLAN
INFORMATION.*
ITEM 2.          REGISTRANT
INFORMATION AND EMPLOYEE PLAN ANNUAL INFORMATION.*
*  Information required by Part I to be
contained in the Section 10(a) prospectus is omitted from this Registration
Statement in accordance with Rule 428 under the Securities Act and the Note to
Part I of Form S-8.
PART II
INFORMATION REQUIRED IN
THE REGISTRATION STATEMENT
ITEM 3.  INCORPORATION OF DOCUMENTS BY REFERENCE.
The following documents, which have heretofore been
filed by the Company with the Commission pursuant to the Securities Exchange
Act of 1934, as amended (the "Exchange Act"), are incorporated by reference
herein and shall be deemed to be a part hereof:
(a)        The Company's Annual
Report on Form 10-K for the fiscal year ended  December
31, 2001;
(b)        All reports filed
pursuant to Section 13(a) or 15(d) of the Exchange Act since  December 31, 2001, including the Company's
Quarterly Reports on Form 10-Q for
the fiscal quarters ended March 31, 2002, June 30, 2002 and September 30,  2002, three Current Reports on Form 8-K
dated January 25, 2002 and Current  Reports
on Form 8-K dated February 19, 2002, March 6, 2002, June 26, 2002  and November 18, 2002; and
(c)        The description of the
Company's Common Stock, par value $.001 per share, contained in the Company's Registration Statement on Form 8-A filed
under the  Exchange Act on
October 23, 1991, including any amendment or report filed  for the purpose of updating such description.
All other documents filed by the Company with the
Commission pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act
subsequent to the date of this Registration Statement and prior to the filing
of a post-effective amendment which indicates that all securities offered
herein have been sold or which de-registers all securities then remaining
unsold, shall be deemed to be incorporated by reference in this Registration
Statement and to be a part hereof from the date of filing of such documents
(such documents, and the documents enumerated above, being hereinafter referred
to collectively as the "Incorporated Documents").
Any statement contained in an Incorporated Document
shall be deemed to be modified or superseded for purposes of this Registration
Statement to the extent that a statement contained therein or in any other
subsequently filed Incorporated Document modifies or supersedes such
statement.  Any such statements so
modified or superseded shall not be deemed, except as so modified or
superseded, to constitute a part of this Registration Statement.
ITEM 4.          DESCRIPTION OF SECURITIES.
Not applicable.
ITEM 5.          INTERESTS
OF NAMED EXPERTS AND COUNSEL.
Certain legal matters with respect to the offering of
the shares of Company Common Stock registered hereby have been passed upon by
Catherine M. Vaczy, Vice President, Legal and Associate General Counsel of the
Company.  Ms. Vaczy owns Company Common
Stock and holds employee stock options to purchase Company Common Stock.
ITEM
6.          INDEMNIFICATION OF DIRECTORS
AND OFFICERS.
The Company's Certificate of Incorporation and Bylaws set forth the
extent to which officers and directors of the Company may be indemnified
against any liabilities which they may incur. 
The general effect of such provisions is that, on the terms and
conditions set forth in the Company's Certificate of Incorporation and Bylaws, any person made a party or
threatened to be made a party to an action, suit or proceeding by reason of the
fact that he or she is or was a director, officer or employee of the Company,
or is or was serving as a director, officer, employee or agent of another
corporation or other enterprise at the request of the Company, shall be
indemnified by the Company against expenses (including attorneys' fees,
judgments, fines and amounts paid in settlement) reasonably incurred or
suffered by him or her in connection with such action, suit or proceeding, to
the full extent permitted under the laws of the State of Delaware; provided,
however, that, subject to certain limited exceptions, the Company shall
indemnify any such person seeking indemnification in connection with a
proceeding initiated by such person only if such proceeding was authorized by
the Board of Directors of the Company. 
The Company's Certificate of Incorporation gives the Board of Directors
of the Company the authority to extend such indemnification to employees and
other agents of the Company as well.
The general effect of the indemnification provisions contained in Section 145 of the General Corporation Law of the State of Delaware (the "DGCL") is as follows:  A director or officer who, by reason of such directorship or officership,
is involved in any action, suit or proceeding (other than an action by or in the right of the corporation) shall be indemnified by the corporation against expenses (including attorneys' fees), judgments, fines and amounts paid in settlement actually and reasonably incurred by him or her in connection with such action, suit or proceeding if he or she acted in good faith and in a manner he or she reasonably believed to be in or not opposed to the best interests of the corporation, and, with respect to any criminal action or proceeding, has no reasonable cause to believe that his or her conduct was unlawful.  A director or officer who, by reason of such directorship or officership, is involved in any action or suit by or in the right of the corporation shall be indemnified by the corporation against expenses (including attorneys' fees) actually and reasonably incurred by him or her in connection with the defense or settlement of such action or suit if he or she acted in good faith and in a manner he or she reasonably believed to be in or not opposed to the best interests of the corporation, except that no indemnification shall be made in respect of any claim, issue or matter as to which he or she shall have been adjudged to be liable to the corporation unless and only to the extent that a court of appropriate jurisdiction shall approve such indemnification.
The Company's Certificate of Incorporation provides that, to the maximum extent permitted under the DGCL, a director of the Company shall not be personally liable to the Company or to any of its stockholders for monetary damages for breach of fiduciary duty as a director of the Company.  Section 102(b)(7) of the DGCL permits a corporation to include in its certificate of incorporation a provision that eliminates or limits the personal liability of a director to the corporation or its stockholders for monetary damages for breach of fiduciary duty as a director; provided, that such provision shall not eliminate or limit the liability of a director (i) for any breach of the director's duty of loyalty to the corporation or its stockholders, (ii) for acts or omissions not in good faith or which involve intentional misconduct or a knowing violation of law, (iii)
for unlawful payments of dividends or unlawful stock repurchases, redemptions or
other distributions, or (iv) for any transaction from which the director derived an improper personal benefit.
The Company maintains standard policies of insurance under which coverage is
provided (a) to its directors and officers against loss arising from claims made
by reason of breach of duty or other wrongful act, and (b) to the Company with
respect to payments which may be made by the Company to such officers and
directors pursuant to the above indemnification provision or otherwise as a
matter of law.
The Company has entered into Employment Agreements with Harlan
W. Waksal, Daniel S. Lynch and S. Joseph Tarnowski pursuant to which the
Company has agreed to advance expenses for the defense of and to indemnify such
persons to the fullest extent permitted by Delaware law.
ITEM 7.          EXEMPTION
FROM REGISTRATION CLAIMED.
Not applicable.
ITEM 8.          EXHIBITS.
Exhibit No.
Exhibit
4.1             Certificate of Incorporation of the
Company, as amended through December 31,
1998 (filed as Exhibit 3.2 to the
Company's Quarterly Report on Form 10-Q for
the quarter ended June 30, 1997).*
4.2             Amendment dated June 4, 1999 to the
Company's Certificate of Incorporation,
as amended (filed as Exhibit 3.1A to
the Company' Quarterly Report on Form
10-Q for the quarter ended June 30, 1999).*
4.3             Amendment dated June 12, 2000 to
the Company's Certificate of Incorporation,
as amended (filed as Exhibit 3.1A
to the Company' Quarterly Report on Form
10-Q for the quarter ended June 30,
2000).*
4.4             Amendment dated August 9, 2002 to
the Company's Certificate of Incorporation,
as amended (filed as Exhibit 3.1C
to the Company' Quarterly Report on Form
10-Q for the quarter ended June 30,
2002).*
4.5             Amended and Restated Bylaws of the
Company (filed as Exhibit 3.2 to the
Company's Current Report on Form 8-K dated
January 21, 1998).*
5.1             Opinion of Catherine M. Vaczy, Esq.
23.1            Consent of KPMG LLP.
23.2            Consent of Catherine M. Vaczy, Esq.
(included in Exhibit 5.1).
24.1            Power of Attorney (included on
signature pages to this Registration Statement).
99.1            ImClone Systems Incorporated 2002
Stock Option Plan (filed as Appendix A to
the definitive Proxy Statement for
the 2002 Annual Meeting of Stockholders, filed
on April 24, 2002).*
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*  Incorporated herein by reference
ITEM 9.          UNDERTAKINGS.
(a)        The
undersigned hereby undertakes:
(1)        To file, during any period in which
offers or sales are being made, a post-effective amendment to this Registration
Statement:
(i)   To include any prospectus required by Section
10(a)(3) of the Securities Act;
(ii)  To reflect in the prospectus any facts or
events arising after the effective date of this Registration Statement (or the
most recent post-effective amendment thereof) which, individually or in the
aggregate, represent a fundamental change in the information set forth in this
Registration Statement.  Notwithstanding
the foregoing, any increase or decrease in volume of securities offered (if the
total dollar value of securities offered would not exceed that which was
registered) and any deviation from the low or high end of the estimated maximum
offering range may be reflected in the form of prospectus filed with the
Commission pursuant to Rule 424(b) if, in the aggregate, the changes in volume
and price represent no more than a 20% change in the maximum aggregate offering
price set forth in the "Calculation of Registration Fee" table in the effective
Registration Statement; and
(iii)To include
any material information with respect to the plan of distribution not
previously disclosed in this Registration Statement or any material change to
such information in this Registration Statement;
provided
,
however
, that paragraphs
(a)(1)(i) and (a)(1)(ii) above do not apply if the registration statement is on
Form S-3, Form S-8 or Form F-3, and the information required to be included in
a post-effective amendment by those paragraphs is contained in periodic reports
filed by the registrant pursuant to Section 13 or Section 15(d) of the Exchange
Act that are incorporated by reference in the registration statement.
(2)        That,
for the purpose of determining any liability under the Securities Act, each
such post-effective amendment shall be deemed to be a new registration
statement relating to the securities offered therein, and the offering of such
securities at that time shall be deemed to be the initial bona fide offering
thereof; and
(3)        To
remove from registration by means of a post-effective amendment any of the
securities being registered which remain unsold at the termination of the
offering.
(b)        The
undersigned registrant hereby undertakes that, for purposes of determining any
liability under the Securities Act, each filing of the registrant's Annual
Report pursuant to Section 13(a) or Section 15(d) of the Exchange Act (and,
where applicable, each filing of an employee benefit plan's Annual Report pursuant
to Section 15(d) of the Exchange Act) that is incorporated by reference in the
registration statement shall be deemed to be a new registration statement
relating to the securities offered therein, and the offering of such securities
at that time shall be deemed to be the initial bona fide offering thereof.
(c)        Insofar
as indemnification for liabilities arising under the Securities Act may be
permitted to directors, officers and controlling persons of the registrant
pursuant to the foregoing provisions, or otherwise, the registrant has been
advised that in the opinion of the Commission such indemnification is against
public policy as expressed in the Securities Act and is, therefore,
unenforceable.  In the event that a claim
for indemnification against such liabilities (other than the payment by the
registrant of expenses incurred or paid by a director, officer or controlling
person of the registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the registrant will, unless in
the opinion of its counsel the matter has been settled by controlling
precedent, submit to a court of appropriate jurisdiction the question whether
such indemnification by it is against public policy as expressed in the Securities
Act and will be governed by the final adjudication of such issue.
SIGNATURES
Pursuant to the requirements of the Securities Act of
1933, as amended, the Registrant certifies that it has reasonable grounds to
believe that it meets all of the requirements for filing on Form S-8 and has
duly caused this Registration Statement to be signed on its behalf by the
undersigned, thereunto duly authorized, in the City of New York, State of New
York, on the 26th day of November, 2002.
IMCLONE SYSTEMS INCORPORATED
By:
/s/Harlan W. Waksal
Harlan W. Waksal
President
  and Chief Executive Officer
POWER OF ATTORNEY
Pursuant to the requirements of the
Securities Act of 1933, as amended, this Registration Statement has been signed
below by the following persons in the capacities indicated on November 26, 2002.
 Each person whose individual signature
appears below hereby authorizes Harlan W. Waksal, Daniel S. Lynch and Clifford R.
Saffron, or any of them, to execute in the name and on behalf of each such
person and to file any amendment to this Registration Statement, and appoints
Harlan W. Waksal, Daniel S. Lynch and Clifford R. Saffron, or any of them, as
attorney-in-fact to sign on his behalf individually and in each capacity stated
below, and to file any amendments to this Registration Statement, including any
and all post-effective amendments.
/s/Robert F. Goldhammer
Chairman
  of the Board of Directors
Robert F. Goldhammer
/s/Harlan W. Waksal
Harlan W. Waksal
President, Chief Executive Officer and Director
(Principal
  Executive Officer)
/s/Daniel S.
  Lynch
Daniel S.
  Lynch
Senior
  Vice President, Finance and Chief
Financial
  Officer (Principal Financial Officer)
/s/Andrew G. Bodnar
Director
Andrew G. Bodnar
/s/Vincent T.
  DeVita, Jr.
Director
Vincent T.
  DeVita, Jr.
/s/David M. Kies
Director
David M. Kies
/s/Paul B. Kopperl
Director
Paul B. Kopperl
/s/Arnold J.
  Levine
Director
Arnold J.
  Levine
/s/John Mendelsohn
Director
John Mendelsohn
/s/William R.
  Miller
Director
William R.
  Miller
/s/Peter S. Ringrose
Director
Peter S. Ringrose
EXHIBIT INDEX
Exhibit
Number
Description
4.1             Certificate of Incorporation of the
Company, as amended through December 31,
1998 (filed as Exhibit 3.2 to the
Company's Quarterly Report on Form 10-Q for
the quarter ended June 30, 1997).*
4.2             Amendment dated June 4, 1999 to the
Company's Certificate of Incorporation,
as amended (filed as Exhibit 3.1A to
the Company' Quarterly Report on Form
10-Q for the quarter ended June 30,
1999).*
4.3             Amendment dated June 12, 2000 to
the Company's Certificate of Incorporation,
as amended (filed as Exhibit 3.1A
to the Company' Quarterly Report on Form
10-Q for the quarter ended June 30,
2000).*
4.4             Amendment dated August 9, 2002 to
the Company's Certificate of Incorporation,
as amended (filed as Exhibit 3.1C
to the Company' Quarterly Report on Form
10-Q for the quarter ended June 30,
2002).*
4.5             Amended and Restated Bylaws of the
Company (filed as Exhibit 3.2 to the
Company's Current Report on Form 8-K dated
January 21, 1998).*
5.1             Opinion of Catherine M. Vaczy, Esq.
23.1            Consent of KPMG LLP.
23.2            Consent of Catherine M. Vaczy, Esq.
(included in Exhibit 5.1 to this Registration Statement).
24.1            Power of Attorney (included on
signature pages to this Registration Statement).
99.1            ImClone Systems Incorporated 2002
Stock Option Plan (filed as Appendix A
to the definitive Proxy Statement for
the 2002 Annual Meeting of Stockholders,
filed on April 24, 2002).*
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*  Incorporated herein by reference