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  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><B>AS FILED WITH THE SECURITIES AND EXCHANGE
  COMMISSION ON AUGUST 16, 2016</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: right"><B>REGISTRATION NO. 333-________</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: right"></P>
  
  <!-- Field: Rule-Page --><DIV ALIGN="LEFT" STYLE="margin-top: 3pt; margin-bottom: 12pt"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid; border-bottom: Black 1pt solid; width: 100%">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: right"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: right"></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><B></B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><B>UNITED STATES</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><B>SECURITIES AND EXCHANGE COMMISSION</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><B>WASHINGTON, D.C. 20549</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><B>FORM S-8</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><B>REGISTRATION STATEMENT</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><B>UNDER</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><B>THE SECURITIES ACT OF 1933</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><B>ICAGEN, INC.</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><I>(Exact name of registrant as specified
  in its charter)</I></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" ALIGN="CENTER" STYLE="font-size: 10pt; width: 75%; border-collapse: collapse">
  <tr>
      <TD STYLE="padding-right: 1.65pt; text-align: center; font-size: 10pt; line-height: 107%; width: 49%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Delaware</b></font></td>
      <TD STYLE="width: 2%">&nbsp;</TD>
      <TD STYLE="padding-right: 1.65pt; text-align: center; font-size: 10pt; line-height: 107%; width: 49%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>20-0982060</b></font></td></tr>
  <tr>
      <TD>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0; text-align: center"><i>(State or other jurisdiction</i></P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0; text-align: center"><i>of incorporation or organization)</i></P></td>
      <TD>&nbsp;</TD>
      <TD>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0; text-align: center"><i>(I.R.S. Employer</i></P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0; text-align: center"><i>Identification Number)</i></P></td></tr>
  </table>
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>4222 Emperor Blvd., Suite 350 </B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>Durham, North Carolina 27703</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>(919) 941- 5206</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><I>(Address, including ZIP code, and telephone
  number,</I></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><I>including area code, of registrant's principal executive office)</I></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>2005 STOCK OPTION PLAN</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>2015 STOCK INCENTIVE PLAN</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><I>(Full title of the Plan)</I></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>Richard Cunningham</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>Icagen, Inc.</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>4222 Emperor Blvd., Suite 350 </B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>Durham, North Carolina 27703</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>(919) 941- 5206</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><I>(Name, address and telephone number
  of agent of services)</I></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B><I>WITH COPIES TO:</I></B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>Leslie Marlow, Esq.</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>Gracin &amp; Marlow, LLP</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>The Chrysler Building</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>405 Lexington Avenue, 26</B> <B><SUP>th</SUP></B>
  <B>Floor</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>New York, New York 10174</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>(212) 907-6457</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><I>(Name, address and telephone number)</I></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Indicate by check mark whether the registrant
  is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions
  of &ldquo;large accelerated filer,&rdquo; &ldquo;accelerated filer&rdquo; and &ldquo;smaller reporting company&rdquo; in Rule 12b-2
  of the Exchange Act. (Do not check if smaller reporting company):</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <table cellspacing="0" cellpadding="0" style="width: 100%; border-collapse: collapse; font-size: 10pt">
  <tr>
      <td style="width: 23%; line-height: 107%">&nbsp;</td>
      <td style="width: 23%; line-height: 107%">&nbsp;</td>
      <td style="width: 23%; line-height: 107%">&nbsp;</td>
      <td style="width: 31%; line-height: 107%">&nbsp;</td></tr>
  <tr style="vertical-align: top">
      <td style="padding-right: 0.8pt; text-align: center; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Large Accelerated Filer </font><font style="font-family: Wingdings; font-size: 10pt">&uml;</font></td>
      <td style="padding-right: 0.8pt; text-align: center; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Accelerated Filer </font><font style="font-family: Wingdings; font-size: 10pt">&uml;</font></td>
      <td style="padding-right: 0.8pt; text-align: center; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Non-Accelerated Filer </font><font style="font-family: Wingdings; font-size: 10pt">&uml;</font></td>
      <td style="padding-right: 0.8pt; text-align: center; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Smaller Reporting Company </font><font style="font-family: Wingdings; font-size: 10pt">&thorn;</font></td></tr>
  </table>
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"></P>
  
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  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center; text-indent: 0.5in">&nbsp;</P>
  
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  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><B>CALCULATION OF REGISTRATION FEE</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: left"></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%">
  <TR STYLE="vertical-align: bottom">
      <TD STYLE="font: 10pt Times New Roman, Times, Serif; border-bottom: Black 1.5pt solid"><P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.3pt 0 0"><B>TITLE&nbsp;OF
                                                                                             SECURITIES BEING REGISTERED</B></P></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; padding-bottom: 1.5pt">&nbsp;</TD>
      <TD COLSPAN="2" STYLE="font: 10pt Times New Roman, Times, Serif; text-align: center; border-bottom: Black 1.5pt solid"><P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.85pt 0 0; text-align: center"><B>AMOUNT&nbsp;TO&nbsp;<BR>
  BE</B></P> <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.85pt 0 0; text-align: center"><B>REGISTERED</B></P> <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.85pt 0 0; text-align: center"><B>(1)(2)</B></P></TD><TD STYLE="padding-bottom: 1.5pt; font: 10pt Times New Roman, Times, Serif">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; padding-bottom: 1.5pt">&nbsp;</TD>
      <TD COLSPAN="2" STYLE="font: 10pt Times New Roman, Times, Serif; text-align: center; border-bottom: Black 1.5pt solid"><P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.85pt 0 0; text-align: center"><B>PROPOSED<BR>
  MAXIMUM</B></P> <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.85pt 0 0; text-align: center"><B>OFFERING&nbsp;PRICE</B><BR> <B>PER
                                                                                                                                                                                                                                                                   SHARE</B></P></TD><TD STYLE="padding-bottom: 1.5pt; font: 10pt Times New Roman, Times, Serif">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; padding-bottom: 1.5pt">&nbsp;</TD>
      <TD COLSPAN="2" STYLE="font: 10pt Times New Roman, Times, Serif; text-align: center; border-bottom: Black 1.5pt solid"><P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.85pt 0 0; text-align: center"><B>PROPOSED</B></P> <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.85pt 0 0; text-align: center"><FONT STYLE="text-transform: uppercase"><B>Maximum </B></FONT><B>AGGREGATE</B></P> <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.85pt 0 0; text-align: center"><B>OFFERING<BR>
  PRICE</B></P></TD><TD STYLE="padding-bottom: 1.5pt; font: 10pt Times New Roman, Times, Serif">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; padding-bottom: 1.5pt">&nbsp;</TD>
      <TD COLSPAN="2" STYLE="font: 10pt Times New Roman, Times, Serif; text-align: center; border-bottom: Black 1.5pt solid"><P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.85pt 0 0; text-align: center"><B>AMOUNT&nbsp;OF</B></P> <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.85pt 0 0; text-align: center"><B>REGISTRATION</B></P> <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.85pt 0 0; text-align: center"><B>FEE&nbsp; (3)</B></P></TD><TD STYLE="padding-bottom: 1.5pt; font: 10pt Times New Roman, Times, Serif">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom">
      <TD STYLE="font-size: 10pt">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
      <TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: right">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
      <TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: right">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
      <TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: right">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
      <TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: right">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
      <TD STYLE="width: 52%; font: 10pt Times New Roman, Times, Serif; text-align: left">Common Stock, par value $0.001 per share, under the 2005 Stock Option Plan</TD><TD STYLE="width: 1%; font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
      <TD STYLE="width: 1%; font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="width: 9%; font: 10pt Times New Roman, Times, Serif; text-align: right">790,770</TD><TD STYLE="width: 1%; font: 10pt Times New Roman, Times, Serif; text-align: left">(4)</TD><TD STYLE="width: 1%; font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
      <TD STYLE="width: 1%; font: 10pt Times New Roman, Times, Serif; text-align: left">$</TD><TD STYLE="width: 9%; font: 10pt Times New Roman, Times, Serif; text-align: right">3.60</TD><TD STYLE="width: 1%; font: 10pt Times New Roman, Times, Serif; text-align: left">(5)</TD><TD STYLE="width: 1%; font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
      <TD STYLE="width: 1%; font: 10pt Times New Roman, Times, Serif; text-align: left">$</TD><TD STYLE="width: 9%; font: 10pt Times New Roman, Times, Serif; text-align: right">2,846,772</TD><TD STYLE="width: 1%; font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="width: 1%; font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
      <TD STYLE="width: 1%; font: 10pt Times New Roman, Times, Serif; text-align: left">$</TD><TD STYLE="width: 9%; font: 10pt Times New Roman, Times, Serif; text-align: right">286.67</TD><TD STYLE="width: 1%; font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
      <TD STYLE="font-size: 10pt">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
      <TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: right">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
      <TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: right">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
      <TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: right">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
      <TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: right">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
      <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">Common Stock, par value $0.001 per share, under the 2015 Stock Incentive Plan</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
      <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">800,000</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">(6)</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
      <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">$</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">3.50</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">(7)</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
      <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">$</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">2,800,000</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
      <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">$</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">281.96</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
      <TD STYLE="font-size: 10pt">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
      <TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: right">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
      <TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: right">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
      <TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: right">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
      <TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: right">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
      <TD STYLE="font: bold 10pt Times New Roman, Times, Serif">Total</TD><TD STYLE="font: bold 10pt Times New Roman, Times, Serif">&nbsp;</TD>
      <TD STYLE="font: bold 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: bold 10pt Times New Roman, Times, Serif; text-align: right">1,590,770</TD><TD STYLE="font: bold 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
      <TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: right">&nbsp;</TD><TD STYLE="font-size: 10pt; text-align: left">&nbsp;</TD><TD STYLE="font: bold 10pt Times New Roman, Times, Serif">&nbsp;</TD>
      <TD STYLE="font: bold 10pt Times New Roman, Times, Serif; text-align: left">$</TD><TD STYLE="font: bold 10pt Times New Roman, Times, Serif; text-align: right">5,646,772</TD><TD STYLE="font: bold 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: bold 10pt Times New Roman, Times, Serif">&nbsp;</TD>
      <TD STYLE="font: bold 10pt Times New Roman, Times, Serif; text-align: left">$</TD><TD STYLE="font: bold 10pt Times New Roman, Times, Serif; text-align: right">568.63</TD><TD STYLE="font: bold 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  </TABLE>
  
  
  
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: left"></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: left"></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&mdash;&mdash;&mdash;&mdash;&mdash;&mdash;&mdash;&mdash;</P>
  
  </P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 2%; padding-right: 0.8pt; line-height: 115%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 106%">(1)</FONT></TD>
      <TD STYLE="width: 98%; padding-right: 0.8pt; text-align: justify; line-height: 115%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 106%">The securities to be registered include options and other rights to acquire the common stock of the Registrant.</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="padding-right: 0.8pt; line-height: 115%">&nbsp;</TD>
      <TD STYLE="padding-right: 0.8pt; line-height: 115%">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="padding-right: 0.8pt; line-height: 115%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 106%">(2)</FONT></TD>
      <TD STYLE="padding-right: 0.8pt; text-align: justify; line-height: 115%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 106%">Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the &ldquo;Securities Act&rdquo;), this registration statement also covers any additional securities that may be offered or issued in connection with any stock split, stock dividend or similar transaction.</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="padding-right: 0.8pt; line-height: 115%">&nbsp;</TD>
      <TD STYLE="padding-right: 0.8pt; text-align: justify; line-height: 115%; text-indent: 2.3pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="padding-right: 1.65pt; line-height: 115%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 106%">(3)</FONT></TD>
      <TD STYLE="padding-right: 1.65pt; text-align: justify; line-height: 115%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 106%">Calculated under Section 6(b) of the Securities Act as .0001007 of the proposed maximum aggregate offering price.</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="padding-right: 1.65pt; line-height: 115%">&nbsp;</TD>
      <TD STYLE="padding-right: 1.65pt; text-align: justify; line-height: 115%">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="padding-right: 1.65pt; line-height: 115%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 106%">(4)</FONT></TD>
      <TD STYLE="padding-right: 1.65pt; text-align: justify; line-height: 115%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 106%">Represents shares of the Registrant&rsquo;s common stock issuable pursuant to outstanding options granted under the Registrant&rsquo;s 2005 Stock Option Plan. The Registrant&rsquo;s 2005 Stock Option Plan has been terminated; no additional stock awards will be granted under the Registrant&rsquo;s 2005 Stock Option Plan and shares are no longer available for the grant of stock awards under the Registrant&rsquo;s 2005 Stock Option Plan. </FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="padding-right: 1.65pt; line-height: 115%">&nbsp;</TD>
      <TD STYLE="padding-right: 1.65pt; text-align: justify; line-height: 115%">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="padding-right: 1.65pt; line-height: 115%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 106%">(5)</FONT></TD>
      <TD STYLE="padding-right: 1.65pt; text-align: justify; line-height: 115%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 106%">Estimated
      solely for the purpose of calculating the amount of the registration fee pursuant to Rule 457(h) of the Securities Act. The
      proposed maximum aggregate offering price per share and proposed maximum aggregate offering price for the 790,770 shares of
      the Registrant&rsquo;s common stock reserved for issuance upon the exercise of outstanding stock options granted under the
      Registrant&rsquo;s 2005 Stock Option Plan are calculated using a weighted average exercise price of $3.60 per share based on
      exercise prices for such outstanding stock options ranging from $0.40 to $11.42 per share.</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="line-height: 115%">&nbsp;</TD>
      <TD STYLE="line-height: 115%">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="line-height: 115%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(6)</FONT></TD>
      <TD STYLE="text-align: justify; line-height: 115%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Represents 602,500 shares of the Registrant&rsquo;s common stock issuable pursuant to outstanding options granted under the Registrant&rsquo;s 2015 Stock Incentive Plan and 197,500 shares of the Registrant&rsquo;s common stock reserved for future grant under the Registrant&rsquo;s 2015 Stock Incentive Plan. </FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="line-height: 115%">&nbsp;</TD>
      <TD STYLE="line-height: 115%">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="line-height: 115%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(7)</FONT></TD>
      <TD STYLE="text-align: justify; line-height: 115%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rule 457(h) of the Securities Act. The proposed maximum aggregate offering price per share and proposed maximum aggregate offering price for the 800,000 shares of the Registrant&rsquo;s common stock reserved for issuance upon the exercise of outstanding stock options granted under the Registrant&rsquo;s 2015 Stock Incentive Plan and future grants are calculated using an exercise price of $3.50 per share, which is the exercise price of 602,500 outstanding options and the book price of the remaining shares available for issuance under the 2015 Stock Incentive Plan.</FONT></TD></TR>
  </TABLE>
  
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in">&nbsp;</P>
  
  <!-- Field: Page; Sequence: 2 -->
      <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 2px solid"></DIV>
      <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt">&nbsp;</DIV>
      <!-- Field: /Page -->
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><B>EXPLANATORY NOTE</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">Icagen, Inc. (the
  &ldquo;Registrant&rdquo; or the &ldquo;Company&rdquo;) hereby files this Registration Statement on Form S-8 relating to its common
  stock, par value $0.001 per share (the &ldquo;Common Stock&rdquo;), which have been reserved for issuance and are issuable pursuant
  to the Company&rsquo;s 2005 Stock Option Plan and the 2015 Stock Incentive Plan (hereinafter referred to as the &ldquo;Plans&rdquo;).</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><B>PART I</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><B>INFORMATION REQUIRED IN THE SECTION
  10(a) PROSPECTUS</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">The information
  specified in Item 1 and Item 2 of Part I of this Registration Statement on Form S-8 (the &ldquo;Registration Statement&rdquo;)
  is omitted from this filing in accordance with the provisions of Rule 428 under the Securities Act of 1933, as amended (the &ldquo;Securities
  Act&rdquo;), and the introductory note to Part I of Form S-8. The documents containing the information specified in Part I will
  be delivered to the participants in the Plans as required by Rule 428(b)(1). Such documents and the documents incorporated by reference
  in this Registration Statement pursuant to Item 3 of Part II of this Registration Statement, taken together, constitute a prospectus
  that meets the requirements of Section 10(a) of the Securities Act.</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><B>PART II</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><B>INFORMATION REQUIRED IN THE REGISTRATION
  STATEMENT</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><B>ITEM 3. INCORPORATION OF DOCUMENTS BY REFERENCE</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">The Securities and
  Exchange Commission (the &ldquo;Commission&rdquo;) allows us to &ldquo;incorporate by reference&rdquo; the information we file
  with it which means that we can disclose important information to you by referring you to those documents instead of having to
  repeat the information in this prospectus. The information incorporated by reference is considered to be part of this prospectus,
  and later information that we file with the Commission will automatically update and supersede this information. We incorporate
  by reference the documents listed below and any future filings made with the Commission under Sections&nbsp;13(a), 13(c), 14 or
  15(d) of the Securities Exchange Act of 1934, as amended (the &ldquo;Exchange Act&rdquo;) between the date of this prospectus and
  the termination of the offering:</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0"></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"></P>
  
  </P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 10%; padding-right: 1.65pt; padding-left: 0.5in; text-align: justify; line-height: 115%"><FONT STYLE="font-family: Symbol; font-size: 10pt; line-height: 106%">&middot;</FONT></TD>
      <TD STYLE="width: 90%; padding-right: 0.8pt; line-height: 115%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 106%">Our Annual Report on Form 10-K for the year ended December 31, 2015 filed with the Commission on April 14, 2016;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="padding-right: 1.65pt; padding-left: 0.5in; text-align: justify; line-height: 115%"><FONT STYLE="font-family: Symbol; font-size: 10pt; line-height: 106%">&middot;</FONT></TD>
      <TD STYLE="padding-right: 0.8pt; line-height: 115%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 106%">Our Quarterly Report on Form 10-Q for the quarter ended March 31, 2016 filed with the Commission on May 19, 2016;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="padding-right: 1.65pt; padding-left: 0.5in; text-align: justify; line-height: 115%"><FONT STYLE="font-family: Symbol; font-size: 10pt; line-height: 106%">&middot;</FONT></TD>
      <TD STYLE="padding-right: 0.8pt; line-height: 115%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 106%">Our Quarterly Report on Form 10-Q for the quarter ended June 30, 2016 filed with the Commission on August 15, 2016;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="padding-right: 1.65pt; padding-left: 0.5in; text-align: justify; line-height: 115%"><FONT STYLE="font-family: Symbol; font-size: 10pt; line-height: 106%">&middot;</FONT></TD>
      <TD STYLE="padding-right: 0.8pt; line-height: 115%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 106%">Our Current Reports on Form 8-K filed with the Commission on February 26, May 20, June 30, July 7 and July 19, 2016; and</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="padding-right: 1.65pt; padding-left: 0.5in; text-align: justify; line-height: 115%"><FONT STYLE="font-family: Symbol; font-size: 10pt; line-height: 106%">&middot;</FONT></TD>
      <TD STYLE="padding-right: 1.65pt; text-align: justify; line-height: 115%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 106%">The description of our common stock set forth in our registration statement on Form&nbsp;8-A, filed with the Commission on June 28, 2012 (File No. 000-54748).</FONT></TD></TR>
  </TABLE>
  
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">All documents filed
  by the Registrant pursuant to Section&nbsp;13(a), 13(c), 14 or 15(d) of the Exchange Act subsequent to the filing of this Registration
  Statement and prior to the filing of a post-effective amendment which indicates that all securities offered hereby have been sold
  or which deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference into this Registration
  Statement and to be a part hereof from the date of filing such documents, except as to specific sections of such documents as
  set forth therein. The Registrant is not, however, incorporating by reference any documents or portions thereof, whether specifically
  listed above or filed in the future, that are not deemed &ldquo;filed&rdquo; with the Commission, including any information furnished
  pursuant to Items 2.02 or 7.01 of Form 8-K or related exhibits furnished pursuant to Item&nbsp;9.01 of Form 8-K. Any statement
  contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or superseded
  for purposes of this Registration Statement to the extent that a statement contained in any subsequently filed document that also
  is deemed to be incorporated by reference herein modifies or supersedes such statement.</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><B>ITEM 4. DESCRIPTION OF SECURITIES</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in">Not applicable.</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><B>ITEM 5. INTERESTS OF NAMED EXPERTS AND COUNSEL</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in">Not applicable.</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <!-- Field: Page; Sequence: 3 -->
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      <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt">&nbsp;</DIV>
      <!-- Field: /Page -->
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><B>ITEM 6. INDEMNIFICATION OF DIRECTORS AND OFFICERS</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">Section 145 of the
  Delaware General Corporation Law authorizes a court to award, or a corporation&rsquo;s board of directors to grant, indemnity to
  directors and officers in terms sufficiently broad to permit such indemnification under certain circumstances for liabilities,
  including reimbursement for expenses incurred, arising under the Securities Act of 1933, as amended (the &ldquo;Securities Act&rdquo;).</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 7.5pt 0 0; text-align: justify; text-indent: 0.5in">Our second
  amended and restated certificate of incorporation, as amended and restated, provides for indemnification of our directors and executive
  officers to the maximum extent permitted by the Delaware General Corporation Law (the &ldquo;DGCL&rdquo;), and our amended and
  restated bylaws provide for indemnification of our directors and executive officers to the maximum extent permitted by the DGCL.</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><B>ITEM 7. EXEMPTION FROM REGISTRATION CLAIMED</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in">Not applicable.</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><B>ITEM 8. EXHIBITS</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in"></P>
  
  <table cellspacing="0" cellpadding="0" style="width: 100%; border-collapse: collapse; font-size: 10pt">
  <tr style="vertical-align: bottom">
      <td style="width: 11%; border-bottom: black 1pt solid; padding-right: 1.65pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Exhibit&nbsp;No.</b></font></td>
      <td style="width: 1%; padding-right: 1.65pt; line-height: 107%">&nbsp;</td>
      <td style="width: 88%; border-bottom: black 1pt solid; padding-right: 1.65pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Description&nbsp;of&nbsp;Document</b></font></td></tr>
  <TR STYLE="vertical-align: top; background-color: rgb(204,238,255)">
      <td>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0">3.1</P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0"></P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0"></P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0"></P></td>
      <td style="padding-right: 1.65pt; line-height: 107%">&nbsp;</td>
      <td>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0">Second Amended and Restated Certificate of Incorporation
          (1)</P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0"></P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0"></P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0"></P></td></tr>
  <TR STYLE="vertical-align: top; background-color: White">
      <TD>3.2</TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">&nbsp;</TD>
      <TD>Certificate of Amendment to Second Amended and
          Restated Certificate of Incorporation (2)</TD></TR>
  <TR STYLE="vertical-align: top; background-color: rgb(204,238,255)">
      <TD>3.3</TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">&nbsp;</TD>
      <TD>Certificate of Amendment to Second Amended and
          Restated Certificate of Incorporation (3)</TD></TR>
  <TR STYLE="vertical-align: top; background-color: White">
      <TD>3.4</TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">&nbsp;</TD>
      <TD>Certificate of Amendment to Second Amended and
          Restated Certificate of Incorporation (4)</TD></TR>
  <TR STYLE="vertical-align: top; background-color: rgb(204,238,255)">
      <td style="padding-right: 1.65pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.5</font></td>
      <td style="padding-right: 1.65pt; line-height: 107%">&nbsp;</td>
      <td style="padding-right: 1.65pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">By-Laws (5)</font></td></tr>
  <TR STYLE="vertical-align: top; background-color: White">
      <td style="padding-right: 1.65pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">4.1</font></td>
      <td style="padding-right: 1.65pt; line-height: 107%">&nbsp;</td>
      <td style="padding-right: 1.65pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2005 Stock Option Plan (1)</font></td></tr>
  <TR STYLE="vertical-align: top; background-color: rgb(204,238,255)">
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">4.2</TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">&nbsp;</TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">2015 Incentive Stock Plan (6)</TD></TR>
  <TR STYLE="vertical-align: top; background-color: White">
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">4.3</TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">&nbsp;</TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">Form of Stock Option Agreement 2005 Incentive
          Stock Plan*</TD></TR>
  <TR STYLE="vertical-align: top; background-color: rgb(204,238,255)">
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">4.4</TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">&nbsp;</TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">Form of Stock Option Agreement 2015 Incentive
          Stock Plan (7)</TD></TR>
  <TR STYLE="vertical-align: top; background-color: White">
      <TD>5.1</TD>
      <TD STYLE="padding-right: 0.8pt; line-height: 107%">&nbsp;</TD>
      <TD>Opinion of Gracin &amp; Marlow, LLP regarding
          Legality of Shares*</TD></TR>
  <TR STYLE="vertical-align: top; background-color: rgb(204,238,255)">
      <TD>23.1</TD>
      <TD STYLE="padding-right: 0.8pt; line-height: 107%">&nbsp;</TD>
      <TD>Consent of RBSM, LLP, Independent Registered Public
          Accounting Firm*</TD></TR>
  <TR STYLE="vertical-align: top; background-color: White">
      <TD>23.2</TD>
      <TD STYLE="padding-right: 0.8pt; line-height: 107%">&nbsp;</TD>
      <TD>Consent of Gracin &amp; Marlow, LLP (contained
          in Exhibit 5.1)</TD></TR>
  <TR STYLE="vertical-align: top; background-color: rgb(204,238,255)">
      <td style="padding-right: 1.65pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">24.1</font></td>
      <td style="padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <td>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0">Power of Attorney of directors and certain
  officers of the Company (included on the signature page of this Registration Statement)&nbsp;</P></td></tr>
  </table>
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 0.25in; text-indent: -0.25in">&mdash;&mdash;&mdash;&mdash;&mdash;&mdash;&mdash;&mdash;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">*Filed herewith</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">(1) Previously filed as Exhibits 3.5 and 4.3 to the Registrant&rsquo;s
  Form S-1 (File No. 333-179508) originally filed with the Securities and Exchange Commission on February 14, 2012</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">(2) Previously filed as Exhibits 3.1 to the Registrant&rsquo;s
  Current Report on Form 8-K (File No. 000-54748) filed with the Securities and Exchange Commission on December 5, 2014</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">(3) Previously filed as Exhibits 3.1 to the Registrant&rsquo;s
  Current Report on Form 8-K (File No. 000-54748) filed with the Securities and Exchange Commission on August 31, 2015</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">(4) Previously filed as Exhibits 3.1 to the Registrant&rsquo;s
  Current Report on Form 8-K (File No. 000-54748) filed with the Securities and Exchange Commission on March 26, 2015</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">(5) Previously filed as Exhibits 3.1 to the Registrant&rsquo;s
  Current Report on Form 8-K (File No. 000-54748) filed with the Securities and Exchange Commission on February 25, 2015</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">(6) Previously filed as Exhibit B to the Registrants Definitive
  Information Statement on Schedule 14C (File No. 000-54748) filed with the Securities and Exchange Commission on March 2, 2016</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">(7) Previously filed as Exhibit 10.2 to the Registrant&rsquo;s
  Current Report on Form 8-K (File No. 000-54748) filed with the Securities and Exchange Commission on December 29, 2015</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <!-- Field: Page; Sequence: 4 -->
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      <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt">&nbsp;</DIV>
      <!-- Field: /Page -->
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><B></B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><B></B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><B>ITEM 9. UNDERTAKINGS</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in">The undersigned Registrant hereby undertakes:</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 1in">1. To file, during
  any period in which offers or sales are being made, a post-effective amendment to this registration statement:</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 1.5in">i. To include any
  prospectus required by Section 10(a)(3) of the Securities Act of 1933, as amended;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 1.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 1.5in">ii. To reflect in
  the prospectus any facts or events arising after the effective date of this registration statement (or the most recent post-effective
  amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in this
  Registration Statement;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 1.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 1.5in">iii. To include
  any material information with respect to the plan of distribution not previously disclosed in this registration statement or any
  material change to such information in the registration statement; provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii)
  do not apply if the information required to be included in a post-effective amendment by those paragraphs is contained in periodic
  reports filed by the Registrant pursuant to Section 13 or Section 15(d) of the Securities Exchange Act of 1934 that are incorporated
  by reference in this Registration Statement.</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 1in">2. That, for the purpose
  of determining any liability under the Securities Act of 1933, each such post-effective amendment shall be deemed to be a new registration
  statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the
  initial bona fide offering thereof.</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 1in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 1in">3. To remove from
  registration by means of a post-effective amendment any of the securities being registered that remain unsold at the termination
  of the offering.</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 1in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 1in">4. That, for purposes
  of determining any liability under the Securities Act of 1933, each filing of the Registrant's annual report pursuant to section
  13(a) or section 15(d) of the Securities Exchange Act of 1934 (and, where applicable, each filing of an employee benefit plan's
  annual report pursuant to section 15(d) of the Securities Exchange Act of 1934) that is incorporated by reference in the registration
  statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such
  securities at that time shall be deemed to be the initial bona fide offering thereof.</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 1in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 1in">5. Insofar as indemnification
  for liabilities arising under the Securities Act of 1933 may be permitted to directors, officers and controlling persons of the
  Registrant, the Registrant has been advised that in the opinion of the SEC such indemnification is against public policy as expressed
  in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities
  (other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant
  in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection
  with the securities being registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by
  controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against
  public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 1in">&nbsp;</P>
  
  <!-- Field: Page; Sequence: 5 -->
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      <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt">&nbsp;</DIV>
      <!-- Field: /Page -->
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 1in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><B>SIGNATURES</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">Pursuant to the
  requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all
  of the requirements for filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned,
  thereunto duly authorized, in Durham, North Carolina, on the 16<SUP>th</SUP> day of August, 2016.</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse; font-size: 10pt">
  <tr style="vertical-align: top">
      <TD STYLE="padding-right: 0.05in; line-height: 107%">&nbsp;</td>
      <td colspan="2" style="padding-right: 4.6pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>ICAGEN, INC.</b></font></td></tr>
  <tr style="vertical-align: top">
      <TD STYLE="padding-right: 0.8pt; line-height: 107%; width: 60%">&nbsp;</td>
      <TD STYLE="padding-right: 0.8pt; line-height: 107%; width: 5%">&nbsp;</td>
      <TD STYLE="padding-right: 0.8pt; line-height: 107%; width: 35%">&nbsp;</td></tr>
  <tr style="vertical-align: top">
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">By:</font></td>
      <TD STYLE="border-bottom: black 1pt solid; padding-right: 1.65pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Richard Cunningham</font></td></tr>
  <tr style="vertical-align: top">
      <TD STYLE="padding-right: 0.05in; line-height: 107%">&nbsp;</td>
      <TD STYLE="padding-right: 0.05in; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Name:</font></td>
      <TD STYLE="padding-right: 0.05in; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Richard Cunningham</font></td></tr>
  <tr style="vertical-align: top">
      <TD STYLE="padding-right: 0.05in; line-height: 107%">&nbsp;</td>
      <TD STYLE="padding-right: 0.05in; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Title:</font></td>
      <TD STYLE="padding-right: 0.05in; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">President and Chief Executive Officer</font></td></tr>
  <tr style="vertical-align: top">
      <TD STYLE="padding-right: 0.05in; line-height: 107%">&nbsp;</td>
      <TD STYLE="padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="padding-right: 0.05in; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Principal Executive Officer)</font></td></tr>
  <tr style="vertical-align: top">
      <TD STYLE="padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="padding-right: 0.8pt; line-height: 107%">&nbsp;</td></tr>
  <tr style="vertical-align: top">
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">By:</font></td>
      <TD STYLE="border-bottom: black 1pt solid; padding-right: 1.65pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Mark Korb</font></td></tr>
  <tr style="vertical-align: top">
      <TD STYLE="padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="padding-right: 0.05in; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Name:</font></td>
      <TD STYLE="padding-right: 0.05in; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Mark Korb</font></td></tr>
  <tr style="vertical-align: top">
      <TD STYLE="padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="padding-right: 0.05in; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Title:</font></td>
      <TD STYLE="padding-right: 0.05in; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Chief Financial Officer</font></td></tr>
  <tr style="vertical-align: top">
      <TD STYLE="padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="padding-right: 0.05in; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Principal Financial and Accounting Officer)</font></td></tr>
  </table>
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0pt 0 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0pt 0 0; text-align: center"><B>POWER OF ATTORNEY AND SIGNATURES
  </B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; text-indent: 0.5in; background-color: white">KNOW
  ALL BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Richard Cunningham and Mark Korb,
  and each of them, as his or her true and lawful attorneys-in-fact and agents, each with the full power of substitution, for him
  or her and in his or her name, place or stead, in any and all capacities, to sign any and all amendments to this Registration Statement,
  and to file the same, with exhibits thereto and other documents in connection therewith, with the Securities and Exchange Commission,
  granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act
  and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as he might or could
  do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or his or their substitute or substitutes,
  may lawfully do or cause to be done by virtue hereof.</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; text-indent: 0.5in; background-color: white">Pursuant
  to the requirements of the Securities Act of 1933, as amended, this Registration Statement has been signed by the following persons
  in the capacities and on the dates indicated.</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; background-color: white; text-indent: 0.5in">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse; font-size: 10pt">
  <tr>
      <TD STYLE="width: 25%; line-height: 107%">&nbsp;</td>
      <TD STYLE="width: 2%; line-height: 107%">&nbsp;</td>
      <TD STYLE="width: 56%; line-height: 107%">&nbsp;</td>
      <TD STYLE="width: 2%; line-height: 107%">&nbsp;</td>
      <TD STYLE="width: 15%; line-height: 107%">&nbsp;</td></tr>
  <tr>
      <TD STYLE="vertical-align: bottom; border-bottom: black 1pt solid; padding-right: 1.55pt; text-align: center; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Signature</b></font></td>
      <TD STYLE="vertical-align: top; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; border-bottom: black 1pt solid; padding-right: 1.55pt; text-align: center; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Title</b></font></td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; border-bottom: black 1pt solid; padding-right: 2.45pt; text-align: center; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Date</b></font></td></tr>
  <tr>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: top; padding-right: 1.55pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 2.45pt; line-height: 107%">&nbsp;</td></tr>
  <tr>
      <TD STYLE="vertical-align: bottom; border-bottom: black 1pt solid; padding-right: 1.55pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Richard Cunningham</font></td>
      <TD STYLE="vertical-align: top; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Chief Executive Officer (Principal Executive Officer) and Director</font></td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; text-align: center; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">August 16, 2016</font></td></tr>
  <tr>
      <TD STYLE="vertical-align: bottom">
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.55pt 0 0">Richard Cunningham</P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.55pt 0 0; text-indent: 0.5in"></P></td>
      <TD STYLE="vertical-align: top; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td></tr>
  <TR>
      <TD STYLE="vertical-align: bottom">&nbsp;</TD>
      <TD STYLE="vertical-align: top; padding-right: 0.8pt; line-height: 107%">&nbsp;</TD>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</TD>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</TD>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</TD></TR>
  <tr>
      <TD STYLE="vertical-align: bottom; border-bottom: black 1pt solid; padding-right: 1.55pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Mark Korb</font></td>
      <TD STYLE="vertical-align: top; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom">
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.55pt 0 0">Chief Financial Officer (Principal Financial and Accounting Officer)</P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.55pt 0 0"></P></td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; text-align: center; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">August 16, 2016</font></td></tr>
  <tr>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Mark Korb</font></td>
      <TD STYLE="vertical-align: top; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%"></td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td></tr>
  <tr>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: top; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; text-align: center; line-height: 107%">&nbsp;</td></tr>
  <tr>
      <TD STYLE="vertical-align: bottom; border-bottom: Black 1pt solid; padding-right: 1.55pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Timothy Tyson</font></td>
      <TD STYLE="vertical-align: top; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Non-Executive Chairman</font></td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; text-align: center; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">August 16, 2016</font></td></tr>
  <tr>
      <TD STYLE="vertical-align: bottom">
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.55pt 0 0">Timothy Tyson</P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.55pt 0 0">&nbsp;</P></td>
      <TD STYLE="vertical-align: top; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; text-align: center; line-height: 107%">&nbsp;</td></tr>
  <tr>
      <TD STYLE="vertical-align: bottom; border-bottom: black 1pt solid; padding-right: 1.55pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Edward Roffman</font></td>
      <TD STYLE="vertical-align: top; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</font></td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; text-align: center; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">August 16, 2016</font></td></tr>
  <tr>
      <TD STYLE="vertical-align: bottom">
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.55pt 0 0">Edward Roffman</P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.55pt 0 0; text-indent: 0.5in">&nbsp;</P></td>
      <TD STYLE="vertical-align: top; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td></tr>
  <tr>
      <TD STYLE="vertical-align: bottom; border-bottom: black 1pt solid; padding-right: 1.55pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Vincent Palmieri</font></td>
      <TD STYLE="vertical-align: top; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</font></td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; text-align: center; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">August 16, 2016</font></td></tr>
  <tr>
      <TD STYLE="vertical-align: bottom">
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.55pt 0 0">Vincent Palmieri</P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.55pt 0 0; text-indent: 0.5in">&nbsp;</P></td>
      <TD STYLE="vertical-align: top; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td></tr>
  <tr>
      <TD STYLE="vertical-align: bottom; border-bottom: black 1pt solid; padding-right: 1.55pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Michael Taglich</font></td>
      <TD STYLE="vertical-align: top; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</font></td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; text-align: center; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">August 16, 2016</font></td></tr>
  <tr>
      <TD STYLE="vertical-align: bottom">
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.55pt 0 0">Michael Taglich</P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.55pt 0 0; text-indent: 0.5in">&nbsp;</P></td>
      <TD STYLE="vertical-align: top; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td></tr>
  <tr>
      <TD STYLE="vertical-align: bottom; border-bottom: black 1pt solid; padding-right: 1.55pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Clive Kabatznik</font></td>
      <TD STYLE="vertical-align: top; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</font></td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; text-align: center; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">August 16, 2016</font></td></tr>
  <tr>
      <TD STYLE="vertical-align: bottom">
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.55pt 0 0">Clive Kabatznik</P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.55pt 0 0; text-indent: 0.5in">&nbsp;</P></td>
      <TD STYLE="vertical-align: top; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td></tr>
  <tr>
      <TD STYLE="vertical-align: bottom; border-bottom: black 1pt solid; padding-right: 1.55pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Benjamin Warner</font></td>
      <TD STYLE="vertical-align: top; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</font></td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 1.55pt; text-align: center; line-height: 107%"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">August 16, 2016</font></td></tr>
  <tr>
      <TD STYLE="vertical-align: bottom">
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.55pt 0 0">Benjamin Warner&nbsp;</P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.55pt 0 0"></P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.55pt 0 0"></P></td>
      <TD STYLE="vertical-align: top; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%"></td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td>
      <TD STYLE="vertical-align: bottom; padding-right: 0.8pt; line-height: 107%">&nbsp;</td></tr>
  </table>
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>
  
  <!-- Field: Page; Sequence: 6 -->
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      <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt">&nbsp;</DIV>
      <!-- Field: /Page -->
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><B>EXHIBIT INDEX</B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><B></B></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in"></P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse; font-size: 10pt">
  <TR STYLE="vertical-align: bottom">
      <TD STYLE="width: 11%; border-bottom: black 1pt solid; padding-right: 1.65pt; line-height: 107%"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>Exhibit&nbsp;No.</B></FONT></TD>
      <TD STYLE="width: 1%; padding-right: 1.65pt; line-height: 107%">&nbsp;</TD>
      <TD STYLE="width: 88%; border-bottom: black 1pt solid; padding-right: 1.65pt; line-height: 107%"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>Description&nbsp;of&nbsp;Document</B></FONT></TD></TR>
  <TR STYLE="vertical-align: top; background-color: rgb(204,238,255)">
      <TD>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0">3.1</P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0"></P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0"></P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0"></P></TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">&nbsp;</TD>
      <TD>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0">Second Amended and Restated Certificate of Incorporation
          (1)</P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0"></P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0"></P>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0"></P></TD></TR>
  <TR STYLE="vertical-align: top; background-color: White">
      <TD>3.2</TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">&nbsp;</TD>
      <TD>Certificate of Amendment to Second Amended and
          Restated Certificate of Incorporation (2)</TD></TR>
  <TR STYLE="vertical-align: top; background-color: rgb(204,238,255)">
      <TD>3.3</TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">&nbsp;</TD>
      <TD>Certificate of Amendment to Second Amended and
          Restated Certificate of Incorporation (3)</TD></TR>
  <TR STYLE="vertical-align: top; background-color: White">
      <TD>3.4</TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">&nbsp;</TD>
      <TD>Certificate of Amendment to Second Amended and
          Restated Certificate of Incorporation (4)</TD></TR>
  <TR STYLE="vertical-align: top; background-color: rgb(204,238,255)">
      <TD STYLE="padding-right: 1.65pt; line-height: 107%"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">3.5</FONT></TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">&nbsp;</TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">By-Laws (5)</FONT></TD></TR>
  <TR STYLE="vertical-align: top; background-color: White">
      <TD STYLE="padding-right: 1.65pt; line-height: 107%"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">4.1</FONT></TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">&nbsp;</TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">2005 Stock Option Plan (1)</FONT></TD></TR>
  <TR STYLE="vertical-align: top; background-color: rgb(204,238,255)">
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">4.2</TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">&nbsp;</TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">2015 Incentive Stock Plan (6)</TD></TR>
  <TR STYLE="vertical-align: top; background-color: White">
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">4.3</TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">&nbsp;</TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">Form of Stock Option Agreement 2005 Incentive
          Stock Plan*</TD></TR>
  <TR STYLE="vertical-align: top; background-color: rgb(204,238,255)">
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">4.4</TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">&nbsp;</TD>
      <TD STYLE="padding-right: 1.65pt; line-height: 107%">Form of Stock Option Agreement 2015 Incentive
          Stock Plan (7)</TD></TR>
  <TR STYLE="vertical-align: top; background-color: White">
      <TD>5.1</TD>
      <TD STYLE="padding-right: 0.8pt; line-height: 107%">&nbsp;</TD>
      <TD>Opinion of Gracin &amp; Marlow, LLP regarding
          Legality of Shares*</TD></TR>
  <TR STYLE="vertical-align: top; background-color: rgb(204,238,255)">
      <TD>23.1</TD>
      <TD STYLE="padding-right: 0.8pt; line-height: 107%">&nbsp;</TD>
      <TD>Consent of RBSM, LLP, Independent Registered Public
          Accounting Firm*</TD></TR>
  <TR STYLE="vertical-align: top; background-color: White">
      <TD>23.2</TD>
      <TD STYLE="padding-right: 0.8pt; line-height: 107%">&nbsp;</TD>
      <TD>Consent of Gracin &amp; Marlow, LLP (contained
          in Exhibit 5.1)</TD></TR>
  <TR STYLE="vertical-align: top; background-color: rgb(204,238,255)">
      <TD STYLE="padding-right: 1.65pt; line-height: 107%"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">24.1</FONT></TD>
      <TD STYLE="padding-right: 0.8pt; line-height: 107%">&nbsp;</TD>
      <TD>
          <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 1.65pt 0 0">Power of Attorney of directors and certain
  officers of the Company (included on the signature page of this Registration Statement)&nbsp;</P></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 0.25in; text-indent: -0.25in">&mdash;&mdash;&mdash;&mdash;&mdash;&mdash;&mdash;&mdash;</P>
  
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 0.25in; text-indent: -0.25in"></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">*Filed herewith</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">(1) Previously filed as Exhibits 3.5 and 4.3 to the Registrant&rsquo;s
  Form S-1 (File No. 333-179508) originally filed with the Securities and Exchange Commission on February 14, 2012</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">(2) Previously filed as Exhibits 3.1 to the Registrant&rsquo;s
  Current Report on Form 8-K (File No. 000-54748) filed with the Securities and Exchange Commission on December 5, 2014</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">(3) Previously filed as Exhibits 3.1 to the Registrant&rsquo;s
  Current Report on Form 8-K (File No. 000-54748) filed with the Securities and Exchange Commission on August 31, 2015</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">(4) Previously filed as Exhibits 3.1 to the Registrant&rsquo;s
  Current Report on Form 8-K (File No. 000-54748) filed with the Securities and Exchange Commission on March 26, 2015</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">(5) Previously filed as Exhibits 3.1 to the Registrant&rsquo;s
  Current Report on Form 8-K (File No. 000-54748) filed with the Securities and Exchange Commission on February 25, 2015</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">(6) Previously filed as Exhibit B to the Registrants Definitive
  Information Statement on Schedule 14C (File No. 000-54748) filed with the Securities and Exchange Commission on March 2, 2016</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">(7) Previously filed as Exhibit 10.2 to the Registrant&rsquo;s
  Current Report on Form 8-K (File No. 000-54748) filed with the Securities and Exchange Commission on December 29, 2015</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"></P>
  
  <!-- Field: Rule-Page --><DIV ALIGN="CENTER" STYLE="margin-top: 3pt; margin-bottom: 3pt"><DIV STYLE="font-size: 1pt; border-top: Black 1.5pt solid; width: 100%">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"></P>
  
  <P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&nbsp;&nbsp;</P>
  
  </BODY>
  </HTML>
metadata_documents: [{"type": "S-8", "sequence": "1", "filename": "fs82016_icageninc.htm", "description": "REGISTRATION STATEMENT", "secsgml_size_bytes": 88471}]
metadata_filer: {"company-data": {"conformed-name": "Icagen, Inc.", "cik": "0001518520", "assigned-sic": "8731", "irs-number": "200982060", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-213173", "film-number": "161837561"}, "business-address": {"street1": "4222 EMPEROR BLVD., SUITE 350", "street2": "RESEARCH TRIANGLE PARK", "city": "DURHAM", "state": "NC", "zip": "27703", "phone": "919-941-5206"}, "mail-address": {"street1": "4222 EMPEROR BLVD., SUITE 350", "street2": "RESEARCH TRIANGLE PARK", "city": "DURHAM", "state": "NC", "zip": "27703"}, "former-company": [{"former-conformed-name": "XRpro Sciences, Inc.", "date-changed": "20141204"}, {"former-conformed-name": "Caldera Pharmaceuticals Inc", "date-changed": "20110419"}]}
text: AS FILED WITH THE SECURITIES AND EXCHANGE
  COMMISSION ON AUGUST 16, 2016
  REGISTRATION NO. 333-________
  UNITED STATES
  SECURITIES AND EXCHANGE COMMISSION
  WASHINGTON, D.C. 20549
  FORM S-8
  REGISTRATION STATEMENT
  UNDER
  THE SECURITIES ACT OF 1933
  ICAGEN, INC.
  (Exact name of registrant as specified
  in its charter)
  Delaware
  20-0982060
  (State or other jurisdiction
  of incorporation or organization)
  (I.R.S. Employer
  Identification Number)
  4222 Emperor Blvd., Suite 350
  Durham, North Carolina 27703
  (919) 941- 5206
  (Address, including ZIP code, and telephone
  number,
  including area code, of registrant's principal executive office)
  2005 STOCK OPTION PLAN
  2015 STOCK INCENTIVE PLAN
  (Full title of the Plan)
  Richard Cunningham
  Icagen, Inc.
  4222 Emperor Blvd., Suite 350
  Durham, North Carolina 27703
  (919) 941- 5206
  (Name, address and telephone number
  of agent of services)
  WITH COPIES TO:
  Leslie Marlow, Esq.
  Gracin & Marlow, LLP
  The Chrysler Building
  405 Lexington Avenue, 26
  th
  Floor
  New York, New York 10174
  (212) 907-6457
  (Name, address and telephone number)
  Indicate by check mark whether the registrant
  is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions
  of "large accelerated filer," "accelerated filer" and "smaller reporting company" in Rule 12b-2
  of the Exchange Act. (Do not check if smaller reporting company):
  Large Accelerated Filer
  ¨
  Accelerated Filer
  ¨
  Non-Accelerated Filer
  ¨
  Smaller Reporting Company
  þ
  CALCULATION OF REGISTRATION FEE
  TITLE OF
                                                                                             SECURITIES BEING REGISTERED
  AMOUNT TO
  BE
  REGISTERED
  (1)(2)
  PROPOSED
  MAXIMUM
  OFFERING PRICE
  PER
                                                                                                                                                                                                                                                                   SHARE
  PROPOSED
  Maximum
  AGGREGATE
  OFFERING
  PRICE
  AMOUNT OF
  REGISTRATION
  FEE  (3)
  Common Stock, par value $0.001 per share, under the 2005 Stock Option Plan
  790,770
  (4)
  $
  3.60
  (5)
  $
  2,846,772
  $
  286.67
  Common Stock, par value $0.001 per share, under the 2015 Stock Incentive Plan
  800,000
  (6)
  $
  3.50
  (7)
  $
  2,800,000
  $
  281.96
  Total
  1,590,770
  $
  5,646,772
  $
  568.63
  ————————
  (1)
  The securities to be registered include options and other rights to acquire the common stock of the Registrant.
  (2)
  Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the "Securities Act"), this registration statement also covers any additional securities that may be offered or issued in connection with any stock split, stock dividend or similar transaction.
  (3)
  Calculated under Section 6(b) of the Securities Act as .0001007 of the proposed maximum aggregate offering price.
  (4)
  Represents shares of the Registrant's common stock issuable pursuant to outstanding options granted under the Registrant's 2005 Stock Option Plan. The Registrant's 2005 Stock Option Plan has been terminated; no additional stock awards will be granted under the Registrant's 2005 Stock Option Plan and shares are no longer available for the grant of stock awards under the Registrant's 2005 Stock Option Plan.
  (5)
  Estimated
      solely for the purpose of calculating the amount of the registration fee pursuant to Rule 457(h) of the Securities Act. The
      proposed maximum aggregate offering price per share and proposed maximum aggregate offering price for the 790,770 shares of
      the Registrant's common stock reserved for issuance upon the exercise of outstanding stock options granted under the
      Registrant's 2005 Stock Option Plan are calculated using a weighted average exercise price of $3.60 per share based on
      exercise prices for such outstanding stock options ranging from $0.40 to $11.42 per share.
  (6)
  Represents 602,500 shares of the Registrant's common stock issuable pursuant to outstanding options granted under the Registrant's 2015 Stock Incentive Plan and 197,500 shares of the Registrant's common stock reserved for future grant under the Registrant's 2015 Stock Incentive Plan.
  (7)
  Estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rule 457(h) of the Securities Act. The proposed maximum aggregate offering price per share and proposed maximum aggregate offering price for the 800,000 shares of the Registrant's common stock reserved for issuance upon the exercise of outstanding stock options granted under the Registrant's 2015 Stock Incentive Plan and future grants are calculated using an exercise price of $3.50 per share, which is the exercise price of 602,500 outstanding options and the book price of the remaining shares available for issuance under the 2015 Stock Incentive Plan.
  EXPLANATORY NOTE
  Icagen, Inc. (the
  "Registrant" or the "Company") hereby files this Registration Statement on Form S-8 relating to its common
  stock, par value $0.001 per share (the "Common Stock"), which have been reserved for issuance and are issuable pursuant
  to the Company's 2005 Stock Option Plan and the 2015 Stock Incentive Plan (hereinafter referred to as the "Plans").
  PART I
  INFORMATION REQUIRED IN THE SECTION
  10(a) PROSPECTUS
  The information
  specified in Item 1 and Item 2 of Part I of this Registration Statement on Form S-8 (the "Registration Statement")
  is omitted from this filing in accordance with the provisions of Rule 428 under the Securities Act of 1933, as amended (the "Securities
  Act"), and the introductory note to Part I of Form S-8. The documents containing the information specified in Part I will
  be delivered to the participants in the Plans as required by Rule 428(b)(1). Such documents and the documents incorporated by reference
  in this Registration Statement pursuant to Item 3 of Part II of this Registration Statement, taken together, constitute a prospectus
  that meets the requirements of Section 10(a) of the Securities Act.
  PART II
  INFORMATION REQUIRED IN THE REGISTRATION
  STATEMENT
  ITEM 3. INCORPORATION OF DOCUMENTS BY REFERENCE
  The Securities and
  Exchange Commission (the "Commission") allows us to "incorporate by reference" the information we file
  with it which means that we can disclose important information to you by referring you to those documents instead of having to
  repeat the information in this prospectus. The information incorporated by reference is considered to be part of this prospectus,
  and later information that we file with the Commission will automatically update and supersede this information. We incorporate
  by reference the documents listed below and any future filings made with the Commission under Sections 13(a), 13(c), 14 or
  15(d) of the Securities Exchange Act of 1934, as amended (the "Exchange Act") between the date of this prospectus and
  the termination of the offering:
  ·
  Our Annual Report on Form 10-K for the year ended December 31, 2015 filed with the Commission on April 14, 2016;
  ·
  Our Quarterly Report on Form 10-Q for the quarter ended March 31, 2016 filed with the Commission on May 19, 2016;
  ·
  Our Quarterly Report on Form 10-Q for the quarter ended June 30, 2016 filed with the Commission on August 15, 2016;
  ·
  Our Current Reports on Form 8-K filed with the Commission on February 26, May 20, June 30, July 7 and July 19, 2016; and
  ·
  The description of our common stock set forth in our registration statement on Form 8-A, filed with the Commission on June 28, 2012 (File No. 000-54748).
  All documents filed
  by the Registrant pursuant to Section 13(a), 13(c), 14 or 15(d) of the Exchange Act subsequent to the filing of this Registration
  Statement and prior to the filing of a post-effective amendment which indicates that all securities offered hereby have been sold
  or which deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference into this Registration
  Statement and to be a part hereof from the date of filing such documents, except as to specific sections of such documents as
  set forth therein. The Registrant is not, however, incorporating by reference any documents or portions thereof, whether specifically
  listed above or filed in the future, that are not deemed "filed" with the Commission, including any information furnished
  pursuant to Items 2.02 or 7.01 of Form 8-K or related exhibits furnished pursuant to Item 9.01 of Form 8-K. Any statement
  contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or superseded
  for purposes of this Registration Statement to the extent that a statement contained in any subsequently filed document that also
  is deemed to be incorporated by reference herein modifies or supersedes such statement.
  ITEM 4. DESCRIPTION OF SECURITIES
  Not applicable.
  ITEM 5. INTERESTS OF NAMED EXPERTS AND COUNSEL
  Not applicable.
  1
  ITEM 6. INDEMNIFICATION OF DIRECTORS AND OFFICERS
  Section 145 of the
  Delaware General Corporation Law authorizes a court to award, or a corporation's board of directors to grant, indemnity to
  directors and officers in terms sufficiently broad to permit such indemnification under certain circumstances for liabilities,
  including reimbursement for expenses incurred, arising under the Securities Act of 1933, as amended (the "Securities Act").
  Our second
  amended and restated certificate of incorporation, as amended and restated, provides for indemnification of our directors and executive
  officers to the maximum extent permitted by the Delaware General Corporation Law (the "DGCL"), and our amended and
  restated bylaws provide for indemnification of our directors and executive officers to the maximum extent permitted by the DGCL.
  ITEM 7. EXEMPTION FROM REGISTRATION CLAIMED
  Not applicable.
  ITEM 8. EXHIBITS
  Exhibit No.
  Description of Document
  3.1
  Second Amended and Restated Certificate of Incorporation
          (1)
  3.2
  Certificate of Amendment to Second Amended and
          Restated Certificate of Incorporation (2)
  3.3
  Certificate of Amendment to Second Amended and
          Restated Certificate of Incorporation (3)
  3.4
  Certificate of Amendment to Second Amended and
          Restated Certificate of Incorporation (4)
  3.5
  By-Laws (5)
  4.1
  2005 Stock Option Plan (1)
  4.2
  2015 Incentive Stock Plan (6)
  4.3
  Form of Stock Option Agreement 2005 Incentive
          Stock Plan*
  4.4
  Form of Stock Option Agreement 2015 Incentive
          Stock Plan (7)
  5.1
  Opinion of Gracin & Marlow, LLP regarding
          Legality of Shares*
  23.1
  Consent of RBSM, LLP, Independent Registered Public
          Accounting Firm*
  23.2
  Consent of Gracin & Marlow, LLP (contained
          in Exhibit 5.1)
  24.1
  Power of Attorney of directors and certain
  officers of the Company (included on the signature page of this Registration Statement)
  ————————
  *Filed herewith
  (1) Previously filed as Exhibits 3.5 and 4.3 to the Registrant's
  Form S-1 (File No. 333-179508) originally filed with the Securities and Exchange Commission on February 14, 2012
  (2) Previously filed as Exhibits 3.1 to the Registrant's
  Current Report on Form 8-K (File No. 000-54748) filed with the Securities and Exchange Commission on December 5, 2014
  (3) Previously filed as Exhibits 3.1 to the Registrant's
  Current Report on Form 8-K (File No. 000-54748) filed with the Securities and Exchange Commission on August 31, 2015
  (4) Previously filed as Exhibits 3.1 to the Registrant's
  Current Report on Form 8-K (File No. 000-54748) filed with the Securities and Exchange Commission on March 26, 2015
  (5) Previously filed as Exhibits 3.1 to the Registrant's
  Current Report on Form 8-K (File No. 000-54748) filed with the Securities and Exchange Commission on February 25, 2015
  (6) Previously filed as Exhibit B to the Registrants Definitive
  Information Statement on Schedule 14C (File No. 000-54748) filed with the Securities and Exchange Commission on March 2, 2016
  (7) Previously filed as Exhibit 10.2 to the Registrant's
  Current Report on Form 8-K (File No. 000-54748) filed with the Securities and Exchange Commission on December 29, 2015
  2
  ITEM 9. UNDERTAKINGS
  The undersigned Registrant hereby undertakes:
  1. To file, during
  any period in which offers or sales are being made, a post-effective amendment to this registration statement:
  i. To include any
  prospectus required by Section 10(a)(3) of the Securities Act of 1933, as amended;
  ii. To reflect in
  the prospectus any facts or events arising after the effective date of this registration statement (or the most recent post-effective
  amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in this
  Registration Statement;
  iii. To include
  any material information with respect to the plan of distribution not previously disclosed in this registration statement or any
  material change to such information in the registration statement; provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii)
  do not apply if the information required to be included in a post-effective amendment by those paragraphs is contained in periodic
  reports filed by the Registrant pursuant to Section 13 or Section 15(d) of the Securities Exchange Act of 1934 that are incorporated
  by reference in this Registration Statement.
  2. That, for the purpose
  of determining any liability under the Securities Act of 1933, each such post-effective amendment shall be deemed to be a new registration
  statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the
  initial bona fide offering thereof.
  3. To remove from
  registration by means of a post-effective amendment any of the securities being registered that remain unsold at the termination
  of the offering.
  4. That, for purposes
  of determining any liability under the Securities Act of 1933, each filing of the Registrant's annual report pursuant to section
  13(a) or section 15(d) of the Securities Exchange Act of 1934 (and, where applicable, each filing of an employee benefit plan's
  annual report pursuant to section 15(d) of the Securities Exchange Act of 1934) that is incorporated by reference in the registration
  statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such
  securities at that time shall be deemed to be the initial bona fide offering thereof.
  5. Insofar as indemnification
  for liabilities arising under the Securities Act of 1933 may be permitted to directors, officers and controlling persons of the
  Registrant, the Registrant has been advised that in the opinion of the SEC such indemnification is against public policy as expressed
  in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities
  (other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant
  in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection
  with the securities being registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by
  controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against
  public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.
  3
  SIGNATURES
  Pursuant to the
  requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all
  of the requirements for filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned,
  thereunto duly authorized, in Durham, North Carolina, on the 16
  th
  day of August, 2016.
  ICAGEN, INC.
  By:
  /s/ Richard Cunningham
  Name:
  Richard Cunningham
  Title:
  President and Chief Executive Officer
  (Principal Executive Officer)
  By:
  /s/ Mark Korb
  Name:
  Mark Korb
  Title:
  Chief Financial Officer
  (Principal Financial and Accounting Officer)
  POWER OF ATTORNEY AND SIGNATURES
  KNOW
  ALL BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Richard Cunningham and Mark Korb,
  and each of them, as his or her true and lawful attorneys-in-fact and agents, each with the full power of substitution, for him
  or her and in his or her name, place or stead, in any and all capacities, to sign any and all amendments to this Registration Statement,
  and to file the same, with exhibits thereto and other documents in connection therewith, with the Securities and Exchange Commission,
  granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act
  and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as he might or could
  do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or his or their substitute or substitutes,
  may lawfully do or cause to be done by virtue hereof.
  Pursuant
  to the requirements of the Securities Act of 1933, as amended, this Registration Statement has been signed by the following persons
  in the capacities and on the dates indicated.
  Signature
  Title
  Date
  /s/ Richard Cunningham
  Chief Executive Officer (Principal Executive Officer) and Director
  August 16, 2016
  Richard Cunningham
  /s/ Mark Korb
  Chief Financial Officer (Principal Financial and Accounting Officer)
  August 16, 2016
  Mark Korb
  /s/ Timothy Tyson
  Non-Executive Chairman
  August 16, 2016
  Timothy Tyson
  /s/ Edward Roffman
  Director
  August 16, 2016
  Edward Roffman
  /s/ Vincent Palmieri
  Director
  August 16, 2016
  Vincent Palmieri
  /s/ Michael Taglich
  Director
  August 16, 2016
  Michael Taglich
  /s/ Clive Kabatznik
  Director
  August 16, 2016
  Clive Kabatznik
  /s/ Benjamin Warner
  Director
  August 16, 2016
  Benjamin Warner
  4
  EXHIBIT INDEX
  Exhibit No.
  Description of Document
  3.1
  Second Amended and Restated Certificate of Incorporation
          (1)
  3.2
  Certificate of Amendment to Second Amended and
          Restated Certificate of Incorporation (2)
  3.3
  Certificate of Amendment to Second Amended and
          Restated Certificate of Incorporation (3)
  3.4
  Certificate of Amendment to Second Amended and
          Restated Certificate of Incorporation (4)
  3.5
  By-Laws (5)
  4.1
  2005 Stock Option Plan (1)
  4.2
  2015 Incentive Stock Plan (6)
  4.3
  Form of Stock Option Agreement 2005 Incentive
          Stock Plan*
  4.4
  Form of Stock Option Agreement 2015 Incentive
          Stock Plan (7)
  5.1
  Opinion of Gracin & Marlow, LLP regarding
          Legality of Shares*
  23.1
  Consent of RBSM, LLP, Independent Registered Public
          Accounting Firm*
  23.2
  Consent of Gracin & Marlow, LLP (contained
          in Exhibit 5.1)
  24.1
  Power of Attorney of directors and certain
  officers of the Company (included on the signature page of this Registration Statement)
  ————————
  *Filed herewith
  (1) Previously filed as Exhibits 3.5 and 4.3 to the Registrant's
  Form S-1 (File No. 333-179508) originally filed with the Securities and Exchange Commission on February 14, 2012
  (2) Previously filed as Exhibits 3.1 to the Registrant's
  Current Report on Form 8-K (File No. 000-54748) filed with the Securities and Exchange Commission on December 5, 2014
  (3) Previously filed as Exhibits 3.1 to the Registrant's
  Current Report on Form 8-K (File No. 000-54748) filed with the Securities and Exchange Commission on August 31, 2015
  (4) Previously filed as Exhibits 3.1 to the Registrant's
  Current Report on Form 8-K (File No. 000-54748) filed with the Securities and Exchange Commission on March 26, 2015
  (5) Previously filed as Exhibits 3.1 to the Registrant's
  Current Report on Form 8-K (File No. 000-54748) filed with the Securities and Exchange Commission on February 25, 2015
  (6) Previously filed as Exhibit B to the Registrants Definitive
  Information Statement on Schedule 14C (File No. 000-54748) filed with the Securities and Exchange Commission on March 2, 2016
  (7) Previously filed as Exhibit 10.2 to the Registrant's
  Current Report on Form 8-K (File No. 000-54748) filed with the Securities and Exchange Commission on December 29, 2015