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  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>As filed with the Securities and Exchange Commission
  on February 23, 2022</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: right"><B>Registration No. 333-&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</B></P>
  
  <!-- Field: Rule-Page --><DIV STYLE="width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid; border-bottom: Black 1pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: right"><B></B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>UNITED STATES</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>SECURITIES AND EXCHANGE COMMISSION</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>Washington, D.C. 20549</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>FORM S-8</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>REGISTRATION STATEMENT</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>Under</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>The Securities Act of 1933</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>EQRX, INC.</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B></B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B></B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">(Exact name of registrant as specified in its charter)</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Arial, Helvetica, Sans-Serif; width: 100%; border-collapse: collapse">
    <TR>
      <TD STYLE="border-bottom: Black 1.5pt solid; vertical-align: top; width: 49%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt"><B>Delaware</B></FONT></TD>
      <TD STYLE="padding: 0.25pt 0.25pt 1.5pt; vertical-align: bottom; width: 2%">&nbsp;</TD>
      <TD STYLE="border-bottom: Black 1.5pt solid; vertical-align: top; width: 49%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt"><B>86-1691173</B></FONT></TD></TR>
    <TR>
      <TD STYLE="vertical-align: top; padding: 0.25pt; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">(State or other jurisdiction of<BR>
  incorporation or organization)</FONT></TD>
      <TD STYLE="vertical-align: bottom; padding: 0.25pt">&nbsp;</TD>
      <TD STYLE="vertical-align: top; padding: 0.25pt; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">(I.R.S. Employer<BR>
  Identification No.)</FONT></TD></TR>
    </TABLE>
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Arial, Helvetica, Sans-Serif; width: 100%; border-collapse: collapse">
    <TR STYLE="vertical-align: top">
      <TD STYLE="width: 49%; text-align: center"><FONT STYLE="font-size: 10pt"><B>50 Hampshire Street</B></FONT></TD>
      <TD STYLE="width: 2%; text-align: center">&nbsp;</TD>
      <TD STYLE="width: 49%; text-align: center">&nbsp;</TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; text-align: center"><FONT STYLE="font-size: 10pt"><B>Cambridge, Massachusetts</B></FONT></TD>
      <TD STYLE="padding-bottom: 1.5pt; text-align: center">&nbsp;</TD>
      <TD STYLE="border-bottom: Black 1.5pt solid; text-align: center"><FONT STYLE="font-size: 10pt"><B>02139</B></FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt">(Address of Principal Executive Offices)</FONT></TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt">(Zip Code)</FONT></TD></TR>
    </TABLE>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>EQRx, Inc. 2019 Stock Option and Grant Plan </B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>EQRx, Inc. 2021 Stock Option and Incentive Plan
  </B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>EQRx, Inc. 2021 Employee Stock Purchase Plan
  </B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">(Full title of the plans)</P>
  
  
  
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"></P>
  
  <!-- Field: Rule-Page --><DIV STYLE="margin-left: auto; margin-right: auto; width: 25%"><DIV STYLE="font-size: 1pt; border-top: Black 1.5pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>Melanie Nallicheri</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>Chief Executive Officer</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>EQRx, Inc.</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>50 Hampshire Street</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>Cambridge, Massachusetts 02139</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">(Name and address of agent for service)</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>(617) 315-2255</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">(Telephone number, including area code, of agent
  for service)</P>
  
  
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B><I>&nbsp;</I></B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"></P>
  
  <!-- Field: Rule-Page --><DIV STYLE="margin-left: auto; margin-right: auto; width: 25%"><DIV STYLE="font-size: 1pt; border-top: Black 1.5pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B><I>&nbsp;</I></B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B><I></I></B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B><I>Copies to:</I></B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Arial, Helvetica, Sans-Serif; width: 100%; border-collapse: collapse">
    <TR STYLE="vertical-align: top">
      <TD STYLE="width: 49%; text-align: center"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt"><B>Jami Rubin</B></FONT></TD>
      <TD STYLE="width: 2%; text-align: center">&nbsp;</TD>
      <TD STYLE="width: 49%; text-align: center"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt"><B>William D. Collins, Esq. </B></FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt"><B>EQRx, Inc.</B></FONT></TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center"><B>Marianne Sarrazin, Esq.</B></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: center"><B>50 Hampshire Street</B></TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt"><B>Goodwin Procter LLP</B></FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: center"><B>Cambridge, Massachusetts 02139</B></TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt"><B>100 Northern Avenue</B></FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: center"><B>Tel: (617) 315-2255</B></TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt"><B>Boston, Massachusetts 02210</B></FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: center"></TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt"><B>Tel: (617) 570-1000</B></FONT></TD></TR>
    </TABLE>
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">Indicate by check mark whether the registrant is a large accelerated
  filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of
  &ldquo;large accelerated filer,&rdquo; &ldquo;accelerated filer,&rdquo; &ldquo;smaller reporting company,&rdquo; and &ldquo;emerging growth
  company&rdquo; in Rule 12b-2 of the Exchange Act.</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Arial, Helvetica, Sans-Serif; width: 100%; border-collapse: collapse">
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0 0 0 0.25in; text-indent: 0; width: 47%; font-size: 10pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Large accelerated filer &#9744;</FONT></TD>
      <TD STYLE="text-indent: 0; width: 2%; padding: 0">&nbsp;</TD>
      <TD STYLE="text-indent: 0; width: 51%; padding: 0; font-size: 10pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Accelerated filer &#9744;</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0 0 0 0.25in; text-indent: 0; font-size: 10pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Non-accelerated filer &#9746;</FONT></TD>
      <TD STYLE="text-indent: 0; padding: 0">&nbsp;</TD>
      <TD STYLE="text-indent: 0; padding: 0">
      <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">Smaller reporting company &#9746;</P>
      <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">Emerging growth company &#9746;</P></TD></TR>
    </TABLE>
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">If an emerging growth company, indicate by check mark if the registrant
  has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant
  to Section 7(a)(2)(B) of the Securities Act. &#9744;</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B></B></P>
  
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  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>
  
  
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  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>PART I</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify">The information required by Part I of Form S-8
  to be contained in the Section 10(a) prospectus is omitted from this registration statement in accordance with Rule 428 under the Securities
  Act of 1933, as amended (the &ldquo;Securities Act&rdquo;). The document(s) containing the information specified in Part I will be sent
  or given to participants in the 2019 Plan, participants in the ESPP and participants in the 2021 Plan (together with the 2021 Plan and
  the ESPP, the &ldquo;Plans&rdquo;) as specified by Rule 428(b)(1) of the Securities Act. Such documents are not being filed with the Securities
  and Exchange Commission (the &ldquo;Commission&rdquo;) as part of this registration statement or as prospectuses or prospectus supplements
  pursuant to Rule 424 of the Securities Act. These document(s) and the documents incorporated by reference in the registration statement
  pursuant to Item 3 of Part II of this form, taken together, constitute a prospectus that meets the requirements of Section 10(a) of the
  Securities Act.</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-indent: 24.5pt">&nbsp;</P>
  
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  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-indent: 24.5pt">&nbsp;</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>PART II</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0"><B>Item 3. Incorporation of Documents by Reference.</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify">The following documents filed with the Commission
  are hereby incorporated by reference in this registration statement:</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0">
  <TR STYLE="vertical-align: top">
  <TD STYLE="width: 0.5in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">(a)</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">The
                                              prospectus filed by the registrant with the Commission pursuant to Rule 424(b)(3) under the
                                              Securities Act, on <A HREF="https://www.sec.gov/Archives/edgar/data/0001843762/000121390021067365/f424b31221_eqrxinc.htm">December
                                              23, 2021</A>, as supplemented on <A HREF="https://www.sec.gov/Archives/edgar/data/1843762/000121390022001218/ea153743-424b3_eqrxinc.htm">January 10, 2022</A>, relating to the registration statement on <A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/0001843762/000121390021066498/fs12021_eqrxinc.htm">Form
                                              S-1</A>, as amended (File No. 333-261786), which contains the registrant&rsquo;s audited
                                              financial statements for the latest fiscal year for which such statements have been filed;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
  <TD>&nbsp;</TD><TD>&nbsp;</TD><TD STYLE="text-align: justify">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
  <TD></TD><TD><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">(b)</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">The
                                              registrant&rsquo;s quarterly reports on Form 10-Q for the quarterly periods ended March 31,
                                              2021 (as filed with the Commission on <A HREF="https://www.sec.gov/Archives/edgar/data/0001843762/000121390021029396/f10q0321_cmlifescience3.htm">May
                                              26, 2021</A>), June 30, 2021 (as filed with the Commission on <A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/0001843762/000121390021043041/f10q0621_cmlife3.htm">August
                                              16, 2021</A>) and September 30, 2021 (as filed with the Commission on <A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/0001843762/000121390021059322/f10q0921_cmlifesciences3.htm">November
                                              15, 2021</A>, as amended on <A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/0001843762/000121390021061645/f10q0921a1_cmlifescie3.htm">November
                                              23, 2021</A>);</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
  <TD>&nbsp;</TD><TD>&nbsp;</TD><TD STYLE="text-align: justify">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
  <TD></TD><TD><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">(c)</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">The
                                              description of the registrant&rsquo;s Common Stock contained in the registrant&rsquo;s registration
                                              statement on Form 8-A, filed by the registrant with the Commission under Section 12(b) of
                                              the Securities Exchange Act of 1934, as amended (the &ldquo;Exchange Act&rdquo;), on <A HREF="https://www.sec.gov/Archives/edgar/data/0001843762/000121390021020139/ea138930-8a12b_cmlife3.htm">April
                                              5, 2021</A>, including any amendments or reports filed for the purpose of updating such description;
                                              and</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
  <TD>&nbsp;</TD><TD>&nbsp;</TD><TD STYLE="text-align: justify">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
  <TD></TD><TD><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">(d)</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">The
  registrant&rsquo;s current reports on Form 8-K filed with the Commission on <A HREF="https://www.sec.gov/Archives/edgar/data/0001843762/000121390021021073/ea139335-8k_cmlife3.htm">April
  9, 2021</A>, <A HREF="https://www.sec.gov/Archives/edgar/data/0001843762/000121390021029469/ea141771-8k_cmlife3.htm">May 27, 2021</A>,
  <A HREF="https://www.sec.gov/Archives/edgar/data/0001843762/000121390021030611/ea139588-8k_cmlife3.htm">June 2, 2021</A>, <A HREF="https://www.sec.gov/Archives/edgar/data/0001843762/000121390021040116/ea145148-8k_cmlifesciences3.htm">August
  3, 2021</A>, <A HREF="https://www.sec.gov/Archives/edgar/data/0001843762/000121390021040657/ea145157-8k_cmlifescien3.htm">August 6, 2021</A>,
  <A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/0001843762/000121390021055250/ea149485-8k_cmlife3.htm">October 29, 2021</A>,
  <A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/0001843762/000121390021061582/ea151227-8k_cmlifesci3.htm">November 23, 2021</A>,
  <A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/0001843762/000121390021065768/ea152521-8k_cmlifesci3.htm">December 17, 2021</A>,
  <A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/0001843762/000121390021066430/ea152198-8k_cmlifesci3.htm">December 20, 2021</A>
  and <A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/0001843762/000121390022001209/ea153739-8k_eqrx.htm">January 10, 2022</A>.</FONT></TD></TR>
  </TABLE>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify">All documents that the registrant subsequently
  files pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act prior to the filing of a post-effective amendment to this registration
  statement that indicates that all of the shares of common stock offered have been sold or that deregisters all of such shares then remaining
  unsold, shall be deemed to be incorporated by reference in this registration statement and to be a part hereof from the date of the filing
  of such documents.</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify"></P>
  
  <!-- Field: Page; Sequence: 3; Options: NewSection; Value: 1 -->
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      <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
      <!-- Field: /Page -->
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify">Any statement contained in a document incorporated
  or deemed to be incorporated by reference herein shall be deemed to be modified or superseded to the extent that a statement contained
  herein or in any other subsequently filed document which also is or is deemed to be incorporated by reference herein modifies or supersedes
  such statement. Any such statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a
  part of this registration statement.</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify">Under no circumstances will any information filed
  under current items 2.02 or 7.01 of Form 8-K be deemed incorporated herein by reference unless such Form 8-K expressly provides to the
  contrary.</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0"><B>Item 4. Description of Securities.</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">Not applicable.</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0"><B>Item 5. Interests of Named Experts and Counsel.</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">Not applicable.</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0"><B>Item 6. Indemnification of Directors and Officers.</B></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify">Section 145 of the Delaware General Corporation
  Law (the &ldquo;DGCL&rdquo;) authorizes a corporation to indemnify its directors and officers against liabilities arising out of actions,
  suits and proceedings to which they are made or threatened to be made a party by reason of the fact that they have served or are currently
  serving as a director or officer to a corporation. The indemnity may cover expenses (including attorneys&rsquo; fees) judgments, fines
  and amounts paid in settlement actually and reasonably incurred by the director or officer in connection with any such action, suit or
  proceeding. Section 145 permits corporations to pay expenses (including attorneys&rsquo; fees) incurred by directors and officers in advance
  of the final disposition of such action, suit or proceeding. In addition, Section 145 provides that a corporation has the power to purchase
  and maintain insurance on behalf of its directors and officers against any liability asserted against them and incurred by them in their
  capacity as a director or officer, or arising out of their status as such, whether or not the corporation would have the power to indemnify
  the director or officer against such liability under Section 145.</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify">The registrant has adopted provisions in the registrant&rsquo;s
  certificate of incorporation and bylaws, which became effective in connection with the completion of the registrant&rsquo;s business combination
  on December 17, 2021, that limit or eliminate the personal liability of the registrant&rsquo;s directors to the fullest extent permitted
  by the DGCL, as it now exists or may in the future be amended. Consequently, a director will not be personally liable to the registrant
  or its stockholders for monetary damages or breach of fiduciary duty as a director, except for liability for:</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-indent: 0.5in"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin-top: 0; margin-bottom: 0; width: 100%"><TR STYLE="vertical-align: top; text-align: justify">
  <TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in; text-align: left"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&#9679;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">any
                                              breach of the director&rsquo;s duty of loyalty to the registrant or its stockholders;</FONT></TD>
  </TR></TABLE>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0 0pt 0.75in"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin-top: 0; margin-bottom: 0; width: 100%"><TR STYLE="vertical-align: top; text-align: justify">
  <TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in; text-align: left"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&#9679;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">any
                                              act or omission not in good faith or that involves intentional misconduct or a knowing violation
                                              of law;</FONT></TD>
  </TR></TABLE>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0 0pt 0.75in"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin-top: 0; margin-bottom: 0; width: 100%"><TR STYLE="vertical-align: top; text-align: justify">
  <TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in; text-align: left"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&#9679;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">any
                                              unlawful payments related to dividends or unlawful stock purchases, redemptions or other
                                              distributions under Section 174 of the DGCL; or</FONT></TD>
  </TR></TABLE>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0 0pt 0.75in"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin-top: 0; margin-bottom: 0; width: 100%"><TR STYLE="vertical-align: top; text-align: justify">
  <TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in; text-align: left"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&#9679;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">any
                                              transaction from which the director derived an improper personal benefit.</FONT></TD>
  </TR></TABLE>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-size: 10pt">These limitations
  of liability do not alter director liability under the federal securities laws and do not affect the availability of equitable remedies
  such as an injunction or rescission.</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-indent: 0.5in"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-indent: 0.5in"></P>
  
  <!-- Field: Page; Sequence: 4; Value: 1 -->
      <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1.5pt solid"><P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; text-align: center; margin-top: 0pt; margin-bottom: 0pt">II-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->2<!-- Field: /Sequence --></P></DIV>
      <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
      <!-- Field: /Page -->
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-indent: 0.5in"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0"><FONT STYLE="font-size: 10pt">In addition, the registrant&rsquo;s bylaws
  provide that:</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-indent: 0.5in"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin-top: 0; margin-bottom: 0; width: 100%"><TR STYLE="vertical-align: top; text-align: justify">
  <TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in; text-align: left"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&#9679;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">the
                                              registrant will indemnify its directors, officers and, in the discretion of its board of
                                              directors, certain employees to the fullest extent permitted by the DGCL, as it now exists
                                              or may in the future be amended; and</FONT></TD>
  </TR></TABLE>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0 0pt 0.5in"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin-top: 0; margin-bottom: 0; width: 100%"><TR STYLE="vertical-align: top; text-align: justify">
  <TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in; text-align: left"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&#9679;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">the
                                              registrant will advance expenses, including attorneys&rsquo; fees, to its directors and,
                                              in the discretion of its board of directors, to its officers and certain employees, in connection
                                              with legal proceedings relating to their service for or on behalf of the registrant, subject
                                              to limited exceptions</FONT></TD>
  </TR></TABLE>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-indent: 0.5in"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-size: 10pt">The registrant has
  entered into indemnification agreements with its directors and executive officers. These agreements provide that the registrant will
  indemnify each of its directors and executive officers to the fullest extent permitted by Delaware law. The registrant will advance expenses,
  including attorneys&rsquo; fees (but excluding judgments, fines and settlement amounts), to each indemnified director or executive officer
  in connection with any proceeding in which indemnification is available and the registrant will indemnify its directors and officers
  for any action or proceeding arising out of that person&rsquo;s services as a director or officer brought on behalf of the registrant
  or in furtherance of the registrant&rsquo;s rights. Additionally, certain of the registrant&rsquo;s directors may have certain rights
  to indemnification, advancement of expenses or insurance provided by their affiliates or other third parties, which indemnification relates
  to and might apply to the same proceedings arising out of such director&rsquo;s services as a director referenced herein. Nonetheless,
  the registrant has agreed in the indemnification agreements that the registrant&rsquo;s obligations to those same directors are primary
  and any obligation of such affiliates or other third parties to advance expenses or to provide indemnification for the expenses or liabilities
  incurred by those directors are secondary.</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-indent: 0.5in"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-size: 10pt">The registrant also
  maintains general liability insurance which covers certain liabilities of its directors and officers arising out of claims based on acts
  or omissions in their capacities as directors or officers, including liabilities under the Securities Act.</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-indent: 0.5in"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0"><FONT STYLE="font-size: 10pt"><B>Item 7. Exemption from Registration
  Claimed.</B></FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0"><FONT STYLE="font-size: 10pt">Not applicable.</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-indent: 0.5in"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  
  <!-- Field: Page; Sequence: 5; Value: 1 -->
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      <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
      <!-- Field: /Page -->
  
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0"><FONT STYLE="font-size: 10pt"><B>&nbsp;</B></FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0"><FONT STYLE="font-size: 10pt"><B>Item 8. Exhibits.</B></FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><FONT STYLE="font-size: 10pt"><B>EXHIBIT INDEX</B></FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-size: 10pt"><B>&nbsp;</B></FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-size: 10pt"><B></B></FONT></P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Arial, Helvetica, Sans-Serif; width: 100%; border-collapse: collapse">
    <TR STYLE="vertical-align: bottom">
      <TD STYLE="border-bottom: Black 1.5pt solid; width: 9%; padding: 0.25pt 0.25pt 0.5pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt"><B>Exhibit&nbsp;No.</B></FONT></TD>
      <TD STYLE="width: 1%; padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="border-bottom: Black 1.5pt solid; padding: 0.25pt 0.25pt 0.5pt; width: 90%; text-align: center"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt"><B>Description</B></FONT></TD></TR>
    <TR>
      <TD STYLE="vertical-align: top; padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="vertical-align: bottom; padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="vertical-align: top; padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
    <TR STYLE="background-color: rgb(204,238,255)">
      <TD STYLE="vertical-align: top; padding: 0.25pt 0.15in 0.25pt 0.25pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">4.1</FONT></TD>
      <TD STYLE="vertical-align: bottom; padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0.25pt; vertical-align: top; text-align: justify"><A HREF="http://www.sec.gov/Archives/edgar/data/1843762/000121390021066430/ea152198ex3-1_cmlifescien3.htm"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Second
      Amended and Restated Certificate of Incorporation of the registrant (incorporated by reference to Exhibit 3.1 to the current report
      on Form 8-K, filed with the Commission on December 20, 2021).</FONT></A></TD></TR>
    <TR STYLE="background-color: White">
      <TD STYLE="text-align: justify; vertical-align: top; padding: 0.25pt 0.15in 0.25pt 0.25pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">4.2</FONT></TD>
      <TD STYLE="text-align: justify; vertical-align: bottom; padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0.25pt; vertical-align: top; text-align: justify"><A HREF="http://www.sec.gov/Archives/edgar/data/1843762/000121390021066430/ea152198ex3-2_cmlifescien3.htm"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Amended
      and Restated Bylaws of the registrant (incorporated by reference to Exhibit 3.2 to the current report on Form 8-K filed with the
      Commission on December 20, 2021).</FONT></A></TD></TR>
    <TR STYLE="background-color: rgb(204,238,255)">
      <TD STYLE="text-align: justify; vertical-align: top; padding: 0.25pt 0.15in 0.25pt 0.25pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">5.1*</FONT></TD>
      <TD STYLE="text-align: justify; vertical-align: bottom; padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0.25pt; vertical-align: top; text-align: justify"><A HREF="ea155911ex5-1_eqrxinc.htm"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Opinion of Goodwin Procter LLP.</FONT></A></TD></TR>
    <TR STYLE="background-color: White">
      <TD STYLE="text-align: justify; vertical-align: top; padding: 0.25pt 0.15in 0.25pt 0.25pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">23.1*</FONT></TD>
      <TD STYLE="text-align: justify; vertical-align: bottom; padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0.25pt; vertical-align: top; text-align: justify"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt"><A HREF="ea155911ex23-1_eqrxinc.htm">Consent of WithumSmith+Brown, PC</A></FONT></TD></TR>
    <TR STYLE="background-color: rgb(204,238,255)">
      <TD STYLE="text-align: justify; vertical-align: top; padding: 0.25pt 0.15in 0.25pt 0.25pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">23.2*</FONT></TD>
      <TD STYLE="text-align: justify; vertical-align: bottom; padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0.25pt; vertical-align: top; text-align: justify"><A HREF="ea155911ex23-2_eqrxinc.htm"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Consent of Ernst &amp; Young LLP, independent registered public accounting firm.</FONT></A></TD></TR>
    <TR STYLE="background-color: White">
      <TD STYLE="text-align: justify; vertical-align: top; padding: 0.25pt 0.15in 0.25pt 0.25pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">23.3*</FONT></TD>
      <TD STYLE="text-align: justify; vertical-align: bottom; padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0.25pt; vertical-align: top; text-align: justify"><A HREF="ea155911ex5-1_eqrxinc.htm"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Consent of Goodwin Procter LLP (included in Exhibit 5.1).</FONT></A></TD></TR>
    <TR STYLE="background-color: rgb(204,238,255)">
      <TD STYLE="text-align: justify; vertical-align: top; padding: 0.25pt 0.15in 0.25pt 0.25pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">24.1*</FONT></TD>
      <TD STYLE="text-align: justify; vertical-align: bottom; padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0.25pt; vertical-align: top; text-align: justify"><A HREF="#pow_001"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Power
      of Attorney (included on signature page of this registration statement).</FONT></A></TD></TR>
    <TR STYLE="background-color: White">
      <TD STYLE="text-align: justify; vertical-align: top; padding: 0.25pt 0.15in 0.25pt 0.25pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">99.1</FONT></TD>
      <TD STYLE="text-align: justify; vertical-align: bottom; padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0.25pt; vertical-align: top; text-align: justify"><A HREF="http://www.sec.gov/Archives/edgar/data/1843762/000121390021044765/fs42021ex10-3_cmlifescien3.htm"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">EQRx,
      Inc. 2019 Stock Option and Grant Plan (incorporated by reference to Exhibit 10.3 to the registration statement on Form S-4 (File
      No. 333-259054) filed with the Commission on August 25, 2021).</FONT></A></TD></TR>
    <TR STYLE="background-color: rgb(204,238,255)">
      <TD STYLE="text-align: justify; vertical-align: top; padding: 0.25pt 0.15in 0.25pt 0.25pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">99.2</FONT></TD>
      <TD STYLE="text-align: justify; vertical-align: bottom; padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0.25pt; vertical-align: top; text-align: justify"><A HREF="http://www.sec.gov/Archives/edgar/data/1843762/000121390021051237/fs42021a1ex10-4_cmlifesci3.htm"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Form
      of Incentive Stock Option Grant Notice, Non-Qualified Stock Option Grant Notice, Early Exercise Non-Qualified Stock Option Grant
      Notice, and Restricted Stock Award Notice, under the EQRx, Inc. 2019 Stock Option and Grant Plan (incorporated by reference to Exhibit
      10.4 to the registration statement on Form S-4/A (File No. 333-259054) deemed filed by the registrant on October 4, 2021).</FONT></A></TD></TR>
    <TR STYLE="background-color: White">
      <TD STYLE="text-align: justify; vertical-align: top; padding: 0.25pt 0.15in 0.25pt 0.25pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">99.3</FONT></TD>
      <TD STYLE="text-align: justify; vertical-align: bottom; padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0.25pt; vertical-align: top; text-align: justify"><A HREF="http://www.sec.gov/Archives/edgar/data/1843762/000121390021066430/ea152198ex10-8_cmlifescien3.htm"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">EQRx,
      Inc. 2021 Stock Option and Incentive Plan (incorporated by reference to Exhibit 10.8 to the current report on Form 8-K, filed with
      the Commission on December 20, 2021).</FONT></A></TD></TR>
    <TR STYLE="background-color: rgb(204,238,255)">
      <TD STYLE="text-align: justify; vertical-align: top; padding: 0.25pt 0.15in 0.25pt 0.25pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">99.4</FONT></TD>
      <TD STYLE="text-align: justify; vertical-align: bottom; padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0.25pt; vertical-align: top; text-align: justify"><A HREF="http://www.sec.gov/Archives/edgar/data/1843762/000121390021066430/ea152198ex10-9_cmlifescien3.htm"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Form
      of Incentive Stock Option Agreement, Non-Qualified Stock Option Agreement for Non-Employee Directors, Non-Qualified Stock Option
      Agreement for Company Employees, Restricted Stock Award Agreement, Restricted Stock Unit Award Agreement for Non-Employee Directors
      and Restricted Stock Unit Award Agreement for Company Employees under the EQRX, Inc. 2021 Stock Option and Incentive Plan (incorporated
      by reference to Exhibit 10.9 to the current report on Form 8-K, filed with the Commission on December 20, 2021).</FONT></A></TD></TR>
    <TR STYLE="background-color: White">
      <TD STYLE="text-align: justify; vertical-align: top; padding: 0.25pt 0.15in 0.25pt 0.25pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">99.5</FONT></TD>
      <TD STYLE="text-align: justify; vertical-align: bottom; padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0.25pt; vertical-align: top; text-align: justify"><A HREF="http://www.sec.gov/Archives/edgar/data/1843762/000121390021066430/ea152198ex10-10_cmlifescien3.htm"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">EQRx,
      Inc. 2021 Employee Stock Purchase Plan (incorporated by reference to Exhibit 10.10 to the current report on Form 8-K, filed with
      the Commission on December 20, 2021).</FONT></A></TD></TR>
    <TR STYLE="background-color: rgb(204,238,255)">
      <TD STYLE="vertical-align: top; padding: 0.25pt 0.15in 0.25pt 0.25pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">107*</FONT></TD>
      <TD STYLE="vertical-align: bottom; padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="vertical-align: top; padding: 0.25pt; text-align: justify"><A HREF="ea155911ex-fee_eqrxinc.htm"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Filing Fee Table</FONT></A></TD></TR>
    </TABLE>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-size: 10pt"><B>&nbsp;</B></FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0 0pt 0.5in; text-indent: -0.5in"><FONT STYLE="font-size: 10pt"></FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0 0pt 0.5in; text-indent: -0.5in"></P>
  
  <!-- Field: Rule-Page --><DIV STYLE="width: 25%"><DIV STYLE="font-size: 1pt; border-top: Black 1.5pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0 0pt 0.5in; text-indent: -0.5in"><FONT STYLE="font-size: 10pt"></FONT></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin-top: 0; margin-bottom: 0; width: 100%"><TR STYLE="vertical-align: top; text-align: justify">
  <TD STYLE="width: 0in"></TD><TD STYLE="width: 0.25in; text-align: left"><FONT STYLE="font-size: 10pt">*</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt">Filed herewith.</FONT></TD>
  </TR></TABLE>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0 0pt 0.5in; text-indent: -0.5in"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-size: 10pt"><B>Item 9. Undertakings.</B></FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-size: 10pt">(a) The registrant
  hereby undertakes:</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify; text-indent: 15pt"><FONT STYLE="font-size: 10pt">(1)
  To file, during any period in which offers or sales are being made, a post-effective amendment to this registration statement:</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify; text-indent: 15pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-size: 10pt">(i)
  To include any prospectus required by Section 10(a)(3) of the Securities Act;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-size: 10pt">(ii)
  To reflect in the prospectus any facts or events arising after the effective date of the registration statement (or the most recent post-effective
  amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the Registration
  Statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities
  offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range
  may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the changes in volume
  and price represent no more than a 20% change in the maximum aggregate offering price set forth in the &ldquo;Calculation of Registration
  Fee&rdquo; table in the effective Registration Statement; and</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-size: 10pt"></FONT></P>
  
  <!-- Field: Page; Sequence: 6; Value: 1 -->
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      <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
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  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-size: 10pt">(iii)
  To include any material information with respect to the plan of distribution not previously disclosed in the registration statement or
  any material change to such information in the registration statement.</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-size: 10pt"><I>Provided,
  however</I>, that paragraphs (a)(1)(i) and (a)(1)(ii) herein do not apply if the information required to be included in a post-effective
  amendment by those paragraphs is contained in reports filed with or furnished to the Commission by the registrant pursuant to Section
  13 or Section 15(d) of the Exchange Act (15 U.S.C. 78m or 78o(d)) that are incorporated by reference in the Registration Statement.</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify; text-indent: 12.75pt"><FONT STYLE="font-size: 10pt">(2)
  That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be
  a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed
  to be the initial bona fide offering thereof.</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify; text-indent: 12.75pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify; text-indent: 12.75pt"><FONT STYLE="font-size: 10pt">(3)
  To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the
  termination of the offering.</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify; text-indent: 12.75pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-size: 10pt">(b) The undersigned
  registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the registrant&rsquo;s
  annual report pursuant to Section 13(a) or Section 15(d) of the Exchange Act (and, where applicable, each filing of an employee benefit
  plan&rsquo;s annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in the registration statement
  shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at
  that time shall be deemed to be the initial bona fide offering thereof.</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-size: 10pt">(c) Insofar as indemnification
  for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the registrant pursuant
  to the foregoing provisions, or otherwise, the registrant has been advised that in the opinion of the Commission such indemnification
  is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification
  against such liabilities (other than the payment by the registrant of expenses incurred or paid by a director, officer or controlling
  person of the registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling
  person in connection with the securities being registered, the registrant will, unless in the opinion of its counsel the matter has been
  settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against
  public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  
  <!-- Field: Page; Sequence: 7; Value: 1 -->
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      <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
      <!-- Field: /Page -->
  
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-size: 10pt"><B>SIGNATURES</B></FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-size: 10pt">Pursuant to the
  requirements of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all of the
  requirements for filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto
  duly authorized, in the City of Cambridge, Massachusetts, on February 23, 2022.</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-indent: 0.25in"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Arial, Helvetica, Sans-Serif; width: 100%; border-collapse: collapse">
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD COLSPAN="2" STYLE="padding: 0.25pt; font-size: 10pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt"><B>EQRX,
      INC. </B></FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD COLSPAN="2" STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="width: 60%; padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="width: 5%; padding: 0.25pt; font-size: 10pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">By:</FONT></TD>
      <TD STYLE="border-bottom: Black 1.5pt solid; width: 35%; padding: 0.25pt 0.25pt 0.5pt; font-size: 10pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">/s/
      Melanie Nallicheri</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0.25pt; font-size: 10pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Name:</FONT></TD>
      <TD STYLE="padding: 0.25pt; font-size: 10pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Melanie Nallicheri</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0.25pt; font-size: 10pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Title:</FONT></TD>
      <TD STYLE="padding: 0.25pt; font-size: 10pt"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">President and
      Chief Executive Officer</FONT></TD></TR>
    </TABLE>
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-size: 10pt"><B>&nbsp;</B></FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-size: 10pt"><B><A NAME="pow_001"></A>POWER OF ATTORNEY
  AND SIGNATURES</B></FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-size: 10pt">KNOW ALL PERSONS
  BY THESE PRESENTS, that each individual whose signature appears below hereby constitutes and appoints each of Melanie Nallicheri and
  Jami Rubin as such person&rsquo;s true and lawful attorney-in-fact and agent with full power of substitution and resubstitution, for
  such person in such person&rsquo;s name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective
  amendments) to this registration statement on Form S-8, and to file the same, with all exhibits thereto, and all documents in connection
  therewith, with the Commission granting unto each said attorney-in-fact and agent full power and authority to do and perform each and
  every act and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as such person
  might or could do in person, hereby ratifying and confirming all that any said attorney-in-fact and agent, or any substitute or substitutes
  of any of them, may lawfully do or cause to be done by virtue hereof.</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-indent: 0.25in"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-size: 10pt">Pursuant to the
  requirements of the Securities Act of 1933, this registration statement has been signed by the following person in the capacities and
  on the date indicated below.</FONT></P>
  
  <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-indent: 0.25in"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Arial, Helvetica, Sans-Serif; width: 100%; border-collapse: collapse">
    <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding: 0; text-align: left; text-indent: 0; width: 36%"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt"><B>Signature</B></FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0; width: 2%"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt"><B>&nbsp;</B></FONT></TD>
      <TD STYLE="text-indent: 0; border-bottom: Black 1.5pt solid; padding: 0; text-align: center; width: 40%"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt"><B>Title</B></FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0; width: 2%"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt"><B>&nbsp;</B></FONT></TD>
      <TD STYLE="text-indent: 0; border-bottom: Black 1.5pt solid; padding: 0; text-align: center; width: 20%"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt"><B>Date</B></FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding: 0; text-align: left; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">/s/
      Melanie Nallicheri</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; padding: 0; text-align: center"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">President,
      Chief Executive Officer and Director</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; padding: 0; text-align: center"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">February
      23, 2022</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Melanie Nallicheri</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">(Principal
      Executive Officer)</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">/s/
      Jami Rubin</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Chief
      Financial Officer</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">February
      23, 2022</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Jami Rubin</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">(Principal
      Financial Officer and Principal Accounting Officer)</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">/s/
      <FONT STYLE="background-color: white">Alexis Borisy</FONT></FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Chairman
      of the Board</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">February
      23, 2022</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt; background-color: white">Alexis
      Borisy</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">/s/
      <FONT STYLE="background-color: white">Amy Abernethy</FONT></FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Director</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">February
      23, 2022</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt; background-color: white">Amy
      Abernethy</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">/s/
      Paul Berns</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Director</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">February
      23, 2022</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Paul Berns</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">/s/
      Eli Casdin</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Director</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">February
      23, 2022</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Eli Casdin</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding: 0; text-indent: 0"></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Director</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0">&nbsp;</TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt; background-color: white">Jorge
      Conde</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">/s/
      <FONT STYLE="background-color: white">Kathryn Giusti</FONT></FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Director</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">February
      23, 2022</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt; background-color: white">Kathryn
      Giusti</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">/s/
      <FONT STYLE="background-color: white">Sandra Horning</FONT></FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Director</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">February
      23, 2022</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt; background-color: white">Sandra
      Horning</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">/s/
      Clive Meanwell</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Director</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">February
      23, 2022</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Clive Meanwell</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 8pt">&nbsp;</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">/s/
      Samuel Merksamer</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Director</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">February
      23, 2022</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Samuel Merksamer</FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"></TD>
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      <TD STYLE="border-bottom: Black 1.5pt solid; padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">/s/
      <FONT STYLE="background-color: white">Krishna Yeshwant</FONT></FONT></TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">Director</FONT></TD>
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      <TD STYLE="text-indent: 0; text-align: center; padding: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt">February
      23, 2022</FONT></TD></TR>
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      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10pt; background-color: white">Krishna
      Yeshwant</FONT></TD>
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metadata_documents: [{"type": "S-8", "sequence": "1", "filename": "ea155911-s8_eqrxinc.htm", "description": "REGISTRATION STATEMENT", "secsgml_size_bytes": 93034}]
metadata_filer: {"company-data": {"conformed-name": "EQRx, Inc.", "cik": "0001843762", "assigned-sic": "2834", "irs-number": "861691173", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-262934", "film-number": "22664867"}, "business-address": {"street1": "50 HAMPSHIRE STREET", "city": "CAMBRIDGE", "state": "MA", "zip": "02139", "phone": "6173152266"}, "mail-address": {"street1": "50 HAMPSHIRE STREET", "city": "CAMBRIDGE", "state": "MA", "zip": "02139"}, "former-company": {"former-conformed-name": "CM Life Sciences III Inc.", "date-changed": "20210201"}}
text: As filed with the Securities and Exchange Commission
  on February 23, 2022
  Registration No. 333-
  UNITED STATES
  SECURITIES AND EXCHANGE COMMISSION
  Washington, D.C. 20549
  FORM S-8
  REGISTRATION STATEMENT
  Under
  The Securities Act of 1933
  EQRX, INC.
  (Exact name of registrant as specified in its charter)
  Delaware
  86-1691173
  (State or other jurisdiction of
  incorporation or organization)
  (I.R.S. Employer
  Identification No.)
  50 Hampshire Street
  Cambridge, Massachusetts
  02139
  (Address of Principal Executive Offices)
  (Zip Code)
  EQRx, Inc. 2019 Stock Option and Grant Plan
  EQRx, Inc. 2021 Stock Option and Incentive Plan
  EQRx, Inc. 2021 Employee Stock Purchase Plan
  (Full title of the plans)
  Melanie Nallicheri
  Chief Executive Officer
  EQRx, Inc.
  50 Hampshire Street
  Cambridge, Massachusetts 02139
  (Name and address of agent for service)
  (617) 315-2255
  (Telephone number, including area code, of agent
  for service)
  Copies to:
  Jami Rubin
  William D. Collins, Esq.
  EQRx, Inc.
  Marianne Sarrazin, Esq.
  50 Hampshire Street
  Goodwin Procter LLP
  Cambridge, Massachusetts 02139
  100 Northern Avenue
  Tel: (617) 315-2255
  Boston, Massachusetts 02210
  Tel: (617) 570-1000
  Indicate by check mark whether the registrant is a large accelerated
  filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of
  "large accelerated filer," "accelerated filer," "smaller reporting company," and "emerging growth
  company" in Rule 12b-2 of the Exchange Act.
  Large accelerated filer ☐
  Accelerated filer ☐
  Non-accelerated filer ☒
  Smaller reporting company ☒
  Emerging growth company ☒
  If an emerging growth company, indicate by check mark if the registrant
  has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant
  to Section 7(a)(2)(B) of the Securities Act. ☐
  PART I
  INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS
  The information required by Part I of Form S-8
  to be contained in the Section 10(a) prospectus is omitted from this registration statement in accordance with Rule 428 under the Securities
  Act of 1933, as amended (the "Securities Act"). The document(s) containing the information specified in Part I will be sent
  or given to participants in the 2019 Plan, participants in the ESPP and participants in the 2021 Plan (together with the 2021 Plan and
  the ESPP, the "Plans") as specified by Rule 428(b)(1) of the Securities Act. Such documents are not being filed with the Securities
  and Exchange Commission (the "Commission") as part of this registration statement or as prospectuses or prospectus supplements
  pursuant to Rule 424 of the Securities Act. These document(s) and the documents incorporated by reference in the registration statement
  pursuant to Item 3 of Part II of this form, taken together, constitute a prospectus that meets the requirements of Section 10(a) of the
  Securities Act.
  1
  PART II
  INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
  Item 3. Incorporation of Documents by Reference.
  The following documents filed with the Commission
  are hereby incorporated by reference in this registration statement:
  (a)
  The
                                              prospectus filed by the registrant with the Commission pursuant to Rule 424(b)(3) under the
                                              Securities Act, on
  December
                                              23, 2021
  , as supplemented on
  January 10, 2022
  , relating to the registration statement on
  Form
                                              S-1
  , as amended (File No. 333-261786), which contains the registrant's audited
                                              financial statements for the latest fiscal year for which such statements have been filed;
  (b)
  The
                                              registrant's quarterly reports on Form 10-Q for the quarterly periods ended March 31,
                                              2021 (as filed with the Commission on
  May
                                              26, 2021
  ), June 30, 2021 (as filed with the Commission on
  August
                                              16, 2021
  ) and September 30, 2021 (as filed with the Commission on
  November
                                              15, 2021
  , as amended on
  November
                                              23, 2021
  );
  (c)
  The
                                              description of the registrant's Common Stock contained in the registrant's registration
                                              statement on Form 8-A, filed by the registrant with the Commission under Section 12(b) of
                                              the Securities Exchange Act of 1934, as amended (the "Exchange Act"), on
  April
                                              5, 2021
  , including any amendments or reports filed for the purpose of updating such description;
                                              and
  (d)
  The
  registrant's current reports on Form 8-K filed with the Commission on
  April
  9, 2021
  ,
  May 27, 2021
  ,
  June 2, 2021
  ,
  August
  3, 2021
  ,
  August 6, 2021
  ,
  October 29, 2021
  ,
  November 23, 2021
  ,
  December 17, 2021
  ,
  December 20, 2021
  and
  January 10, 2022
  .
  All documents that the registrant subsequently
  files pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act prior to the filing of a post-effective amendment to this registration
  statement that indicates that all of the shares of common stock offered have been sold or that deregisters all of such shares then remaining
  unsold, shall be deemed to be incorporated by reference in this registration statement and to be a part hereof from the date of the filing
  of such documents.
  II-
  1
  Any statement contained in a document incorporated
  or deemed to be incorporated by reference herein shall be deemed to be modified or superseded to the extent that a statement contained
  herein or in any other subsequently filed document which also is or is deemed to be incorporated by reference herein modifies or supersedes
  such statement. Any such statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a
  part of this registration statement.
  Under no circumstances will any information filed
  under current items 2.02 or 7.01 of Form 8-K be deemed incorporated herein by reference unless such Form 8-K expressly provides to the
  contrary.
  Item 4. Description of Securities.
  Not applicable.
  Item 5. Interests of Named Experts and Counsel.
  Not applicable.
  Item 6. Indemnification of Directors and Officers.
  Section 145 of the Delaware General Corporation
  Law (the "DGCL") authorizes a corporation to indemnify its directors and officers against liabilities arising out of actions,
  suits and proceedings to which they are made or threatened to be made a party by reason of the fact that they have served or are currently
  serving as a director or officer to a corporation. The indemnity may cover expenses (including attorneys' fees) judgments, fines
  and amounts paid in settlement actually and reasonably incurred by the director or officer in connection with any such action, suit or
  proceeding. Section 145 permits corporations to pay expenses (including attorneys' fees) incurred by directors and officers in advance
  of the final disposition of such action, suit or proceeding. In addition, Section 145 provides that a corporation has the power to purchase
  and maintain insurance on behalf of its directors and officers against any liability asserted against them and incurred by them in their
  capacity as a director or officer, or arising out of their status as such, whether or not the corporation would have the power to indemnify
  the director or officer against such liability under Section 145.
  The registrant has adopted provisions in the registrant's
  certificate of incorporation and bylaws, which became effective in connection with the completion of the registrant's business combination
  on December 17, 2021, that limit or eliminate the personal liability of the registrant's directors to the fullest extent permitted
  by the DGCL, as it now exists or may in the future be amended. Consequently, a director will not be personally liable to the registrant
  or its stockholders for monetary damages or breach of fiduciary duty as a director, except for liability for:
  ●
  any
                                              breach of the director's duty of loyalty to the registrant or its stockholders;
  ●
  any
                                              act or omission not in good faith or that involves intentional misconduct or a knowing violation
                                              of law;
  ●
  any
                                              unlawful payments related to dividends or unlawful stock purchases, redemptions or other
                                              distributions under Section 174 of the DGCL; or
  ●
  any
                                              transaction from which the director derived an improper personal benefit.
  These limitations
  of liability do not alter director liability under the federal securities laws and do not affect the availability of equitable remedies
  such as an injunction or rescission.
  II-
  2
  In addition, the registrant's bylaws
  provide that:
  ●
  the
                                              registrant will indemnify its directors, officers and, in the discretion of its board of
                                              directors, certain employees to the fullest extent permitted by the DGCL, as it now exists
                                              or may in the future be amended; and
  ●
  the
                                              registrant will advance expenses, including attorneys' fees, to its directors and,
                                              in the discretion of its board of directors, to its officers and certain employees, in connection
                                              with legal proceedings relating to their service for or on behalf of the registrant, subject
                                              to limited exceptions
  The registrant has
  entered into indemnification agreements with its directors and executive officers. These agreements provide that the registrant will
  indemnify each of its directors and executive officers to the fullest extent permitted by Delaware law. The registrant will advance expenses,
  including attorneys' fees (but excluding judgments, fines and settlement amounts), to each indemnified director or executive officer
  in connection with any proceeding in which indemnification is available and the registrant will indemnify its directors and officers
  for any action or proceeding arising out of that person's services as a director or officer brought on behalf of the registrant
  or in furtherance of the registrant's rights. Additionally, certain of the registrant's directors may have certain rights
  to indemnification, advancement of expenses or insurance provided by their affiliates or other third parties, which indemnification relates
  to and might apply to the same proceedings arising out of such director's services as a director referenced herein. Nonetheless,
  the registrant has agreed in the indemnification agreements that the registrant's obligations to those same directors are primary
  and any obligation of such affiliates or other third parties to advance expenses or to provide indemnification for the expenses or liabilities
  incurred by those directors are secondary.
  The registrant also
  maintains general liability insurance which covers certain liabilities of its directors and officers arising out of claims based on acts
  or omissions in their capacities as directors or officers, including liabilities under the Securities Act.
  Item 7. Exemption from Registration
  Claimed.
  Not applicable.
  II-
  3
  Item 8. Exhibits.
  EXHIBIT INDEX
  Exhibit No.
  Description
  4.1
  Second
      Amended and Restated Certificate of Incorporation of the registrant (incorporated by reference to Exhibit 3.1 to the current report
      on Form 8-K, filed with the Commission on December 20, 2021).
  4.2
  Amended
      and Restated Bylaws of the registrant (incorporated by reference to Exhibit 3.2 to the current report on Form 8-K filed with the
      Commission on December 20, 2021).
  5.1*
  Opinion of Goodwin Procter LLP.
  23.1*
  Consent of WithumSmith+Brown, PC
  23.2*
  Consent of Ernst & Young LLP, independent registered public accounting firm.
  23.3*
  Consent of Goodwin Procter LLP (included in Exhibit 5.1).
  24.1*
  Power
      of Attorney (included on signature page of this registration statement).
  99.1
  EQRx,
      Inc. 2019 Stock Option and Grant Plan (incorporated by reference to Exhibit 10.3 to the registration statement on Form S-4 (File
      No. 333-259054) filed with the Commission on August 25, 2021).
  99.2
  Form
      of Incentive Stock Option Grant Notice, Non-Qualified Stock Option Grant Notice, Early Exercise Non-Qualified Stock Option Grant
      Notice, and Restricted Stock Award Notice, under the EQRx, Inc. 2019 Stock Option and Grant Plan (incorporated by reference to Exhibit
      10.4 to the registration statement on Form S-4/A (File No. 333-259054) deemed filed by the registrant on October 4, 2021).
  99.3
  EQRx,
      Inc. 2021 Stock Option and Incentive Plan (incorporated by reference to Exhibit 10.8 to the current report on Form 8-K, filed with
      the Commission on December 20, 2021).
  99.4
  Form
      of Incentive Stock Option Agreement, Non-Qualified Stock Option Agreement for Non-Employee Directors, Non-Qualified Stock Option
      Agreement for Company Employees, Restricted Stock Award Agreement, Restricted Stock Unit Award Agreement for Non-Employee Directors
      and Restricted Stock Unit Award Agreement for Company Employees under the EQRX, Inc. 2021 Stock Option and Incentive Plan (incorporated
      by reference to Exhibit 10.9 to the current report on Form 8-K, filed with the Commission on December 20, 2021).
  99.5
  EQRx,
      Inc. 2021 Employee Stock Purchase Plan (incorporated by reference to Exhibit 10.10 to the current report on Form 8-K, filed with
      the Commission on December 20, 2021).
  107*
  Filing Fee Table
  *
  Filed herewith.
  Item 9. Undertakings.
  (a) The registrant
  hereby undertakes:
  (1)
  To file, during any period in which offers or sales are being made, a post-effective amendment to this registration statement:
  (i)
  To include any prospectus required by Section 10(a)(3) of the Securities Act;
  (ii)
  To reflect in the prospectus any facts or events arising after the effective date of the registration statement (or the most recent post-effective
  amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the Registration
  Statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities
  offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range
  may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the changes in volume
  and price represent no more than a 20% change in the maximum aggregate offering price set forth in the "Calculation of Registration
  Fee" table in the effective Registration Statement; and
  II-
  4
  (iii)
  To include any material information with respect to the plan of distribution not previously disclosed in the registration statement or
  any material change to such information in the registration statement.
  Provided,
  however
  , that paragraphs (a)(1)(i) and (a)(1)(ii) herein do not apply if the information required to be included in a post-effective
  amendment by those paragraphs is contained in reports filed with or furnished to the Commission by the registrant pursuant to Section
  13 or Section 15(d) of the Exchange Act (15 U.S.C. 78m or 78o(d)) that are incorporated by reference in the Registration Statement.
  (2)
  That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be
  a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed
  to be the initial bona fide offering thereof.
  (3)
  To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the
  termination of the offering.
  (b) The undersigned
  registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the registrant's
  annual report pursuant to Section 13(a) or Section 15(d) of the Exchange Act (and, where applicable, each filing of an employee benefit
  plan's annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in the registration statement
  shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at
  that time shall be deemed to be the initial bona fide offering thereof.
  (c) Insofar as indemnification
  for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the registrant pursuant
  to the foregoing provisions, or otherwise, the registrant has been advised that in the opinion of the Commission such indemnification
  is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification
  against such liabilities (other than the payment by the registrant of expenses incurred or paid by a director, officer or controlling
  person of the registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling
  person in connection with the securities being registered, the registrant will, unless in the opinion of its counsel the matter has been
  settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against
  public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.
  II-
  5
  SIGNATURES
  Pursuant to the
  requirements of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all of the
  requirements for filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto
  duly authorized, in the City of Cambridge, Massachusetts, on February 23, 2022.
  EQRX,
      INC.
  By:
  /s/
      Melanie Nallicheri
  Name:
  Melanie Nallicheri
  Title:
  President and
      Chief Executive Officer
  POWER OF ATTORNEY
  AND SIGNATURES
  KNOW ALL PERSONS
  BY THESE PRESENTS, that each individual whose signature appears below hereby constitutes and appoints each of Melanie Nallicheri and
  Jami Rubin as such person's true and lawful attorney-in-fact and agent with full power of substitution and resubstitution, for
  such person in such person's name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective
  amendments) to this registration statement on Form S-8, and to file the same, with all exhibits thereto, and all documents in connection
  therewith, with the Commission granting unto each said attorney-in-fact and agent full power and authority to do and perform each and
  every act and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as such person
  might or could do in person, hereby ratifying and confirming all that any said attorney-in-fact and agent, or any substitute or substitutes
  of any of them, may lawfully do or cause to be done by virtue hereof.
  Pursuant to the
  requirements of the Securities Act of 1933, this registration statement has been signed by the following person in the capacities and
  on the date indicated below.
  Signature
  Title
  Date
  /s/
      Melanie Nallicheri
  President,
      Chief Executive Officer and Director
  February
      23, 2022
  Melanie Nallicheri
  (Principal
      Executive Officer)
  /s/
      Jami Rubin
  Chief
      Financial Officer
  February
      23, 2022
  Jami Rubin
  (Principal
      Financial Officer and Principal Accounting Officer)
  /s/
  Alexis Borisy
  Chairman
      of the Board
  February
      23, 2022
  Alexis
      Borisy
  /s/
  Amy Abernethy
  Director
  February
      23, 2022
  Amy
      Abernethy
  /s/
      Paul Berns
  Director
  February
      23, 2022
  Paul Berns
  /s/
      Eli Casdin
  Director
  February
      23, 2022
  Eli Casdin
  Director
  Jorge
      Conde
  /s/
  Kathryn Giusti
  Director
  February
      23, 2022
  Kathryn
      Giusti
  /s/
  Sandra Horning
  Director
  February
      23, 2022
  Sandra
      Horning
  /s/
      Clive Meanwell
  Director
  February
      23, 2022
  Clive Meanwell
  /s/
      Samuel Merksamer
  Director
  February
      23, 2022
  Samuel Merksamer
  /s/
  Krishna Yeshwant
  Director
  February
      23, 2022
  Krishna
      Yeshwant
  II-6