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  <!-- Field: Rule-Page --><DIV STYLE="margin-top: 12pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid; border-bottom: Black 1pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->
  
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>UNITED STATES</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>SECURITIES AND EXCHANGE COMMISSION </B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Washington, D.C. 20549</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>FORM S-8</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>REGISTRATION STATEMENT UNDER THE SECURITIES
  ACT OF 1933</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>INMUNE BIO INC. </B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Exact name of registrant as specified in
  its charter)</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
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      <TD STYLE="width: 50%">
          <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Nevada</B></P>
          <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(State or other jurisdiction of</P>
          <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">incorporation or organization)</P></TD>
      <TD STYLE="width: 50%">
          <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>47-5205835 </B></P>
          <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(I.R.S. Employer</P>
          <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">identification No.)</P></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 3in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>1200 Prospect Street, Suite 525, La Jolla,
  CA 92037</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B>(Address of principal executive
  offices) (Zip Code)</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>INmune Bio Inc. 2017 Stock Incentive
  Plan </B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>INmune Bio Inc. 2019 Stock Incentive
  Plan</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Full title of the plans)</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>David Moss</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Chief Financial Officer</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>INmune Bio, Inc. </B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>1200 Prospect Street, Suite 525,</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>La Jolla, CA 92037</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Name and address of agent for service)</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>585-359-5900</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Telephone number, including area code,
  of agent for service)</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center; background-color: white">Copies to:</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Marc Ross, Esq.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Thomas A. Rose, Esq.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">David B. Manno, Esq.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Sichenzia Ross Ference LLP</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">1185 Avenue of the Americas, 31<SUP>st</SUP>
  Floor</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">New York, New York 10036</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Phone: 212- 930-9700</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Fax: 212-930-9725</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Indicate by check mark whether the registrant
  is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth
  company. See the definitions of &ldquo;large accelerated filer,&rdquo; &ldquo;accelerated filer,&rdquo; &ldquo;smaller reporting
  company,&rdquo; and &quot;emerging growth company&quot; in Rule 12b-2 of the Exchange Act.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; background-color: white">
  <TR>
      <TD STYLE="width: 48%; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Large accelerated
  filer</FONT> &nbsp;&#9744;</TD>
      <TD STYLE="width: 52%; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Accelerated
  filer&nbsp; &#9744;</FONT></TD></TR>
  <TR>
      <TD STYLE="text-align: left; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Non-accelerated
  filer&nbsp; &#9746;</FONT> &nbsp;</TD>
      <TD STYLE="font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Smaller reporting
      company</FONT> &nbsp;&#9746;</TD></TR>
  <TR>
      <TD>&nbsp;</TD>
      <TD STYLE="vertical-align: top; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Emerging
  growth company &nbsp;&#9746;</FONT></TD></TR>
  <TR>
      <TD STYLE="font-size: 10pt">&nbsp;</TD>
      <TD STYLE="font-size: 10pt">&nbsp;</TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">If
  an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for
  complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act.&nbsp;</FONT><FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"></P>
  
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>&nbsp;&nbsp;&nbsp;&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>CALCULATION OF REGISTRATION FEE&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%; font: 10pt Times New Roman, Times, Serif">
  <TR STYLE="vertical-align: bottom">
      <TD STYLE="text-align: center; border-bottom: Black 1.5pt solid"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Title of each class of securities&nbsp;</B></P> <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>to be registered</B></P></TD><TD STYLE="font-weight: bold; padding-bottom: 1.5pt">&nbsp;</TD>
      <TD COLSPAN="2" STYLE="font-weight: bold; text-align: center; border-bottom: Black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Amount to be Registered<SUP>(1)</SUP></B></FONT></TD><TD STYLE="padding-bottom: 1.5pt; font-weight: bold">&nbsp;</TD><TD STYLE="font-weight: bold; padding-bottom: 1.5pt">&nbsp;</TD>
      <TD COLSPAN="2" STYLE="font-weight: bold; text-align: center; border-bottom: Black 1.5pt solid">Proposed Maximum Offering Price Per Security</TD><TD STYLE="padding-bottom: 1.5pt; font-weight: bold">&nbsp;</TD><TD STYLE="font-weight: bold; padding-bottom: 1.5pt">&nbsp;</TD>
      <TD COLSPAN="2" STYLE="font-weight: bold; text-align: center; border-bottom: Black 1.5pt solid">Proposed Maximum Aggregate Offering Price</TD><TD STYLE="padding-bottom: 1.5pt; font-weight: bold">&nbsp;</TD><TD STYLE="font-weight: bold; padding-bottom: 1.5pt">&nbsp;</TD>
      <TD COLSPAN="2" STYLE="font-weight: bold; text-align: center; border-bottom: Black 1.5pt solid">Amount of Registration Fee</TD><TD STYLE="padding-bottom: 1.5pt; font-weight: bold">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
      <TD STYLE="width: 36%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common Stock, $0.001 par value <SUP>(2)</SUP></FONT></TD><TD STYLE="width: 2%">&nbsp;</TD>
      <TD STYLE="width: 1%; text-align: left">&nbsp;</TD><TD STYLE="width: 12%; text-align: right">1,700,000</TD><TD STYLE="width: 1%; text-align: left">&nbsp;</TD><TD STYLE="width: 2%">&nbsp;</TD>
      <TD STYLE="width: 1%; text-align: left">$</TD><TD STYLE="width: 12%; text-align: right">18.81</TD><TD STYLE="width: 1%; text-align: left">&nbsp;</TD><TD STYLE="width: 2%">&nbsp;</TD>
      <TD STYLE="width: 1%; text-align: left">$</TD><TD STYLE="width: 12%; text-align: right">31,977,000</TD><TD STYLE="width: 1%; text-align: left"><SUP>(3)</SUP></TD><TD STYLE="width: 2%">&nbsp;</TD>
      <TD STYLE="width: 1%; text-align: left">$</TD><TD STYLE="width: 12%; text-align: right">3,488.69</TD><TD STYLE="width: 1%; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
      <TD STYLE="padding-bottom: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common Stock, $0.001 par value <SUP>(4) </SUP></FONT></TD><TD STYLE="padding-bottom: 1.5pt">&nbsp;</TD>
      <TD STYLE="border-bottom: Black 1.5pt solid; padding-bottom: 1.5pt; text-align: left">&nbsp;</TD><TD STYLE="border-bottom: Black 1.5pt solid; text-align: right">2,000,000</TD><TD STYLE="padding-bottom: 1.5pt; text-align: left">&nbsp;</TD><TD STYLE="padding-bottom: 1.5pt">&nbsp;</TD>
      <TD STYLE="text-align: left">$</TD><TD STYLE="text-align: right">18.81</TD><TD STYLE="padding-bottom: 1.5pt; text-align: left">&nbsp;</TD><TD STYLE="padding-bottom: 1.5pt">&nbsp;</TD>
      <TD STYLE="border-bottom: Black 1.5pt solid; text-align: left">$</TD><TD STYLE="border-bottom: Black 1.5pt solid; text-align: right">37,620,000</TD><TD STYLE="text-align: left"><SUP>(3)</SUP></TD><TD STYLE="padding-bottom: 1.5pt">&nbsp;</TD>
      <TD STYLE="border-bottom: Black 1.5pt solid; text-align: left">$</TD><TD STYLE="border-bottom: Black 1.5pt solid; text-align: right">4,104.34</TD><TD STYLE="padding-bottom: 1.5pt; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
      <TD STYLE="padding-bottom: 4pt">Total</TD><TD STYLE="padding-bottom: 4pt">&nbsp;</TD>
      <TD STYLE="border-bottom: Black 4pt double; text-align: left">&nbsp;</TD><TD STYLE="border-bottom: Black 4pt double; text-align: right">3,700,000</TD><TD STYLE="padding-bottom: 4pt; text-align: left">&nbsp;</TD><TD STYLE="padding-bottom: 4pt">&nbsp;</TD>
      <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">&nbsp;</TD><TD STYLE="padding-bottom: 4pt; text-align: left">&nbsp;</TD><TD STYLE="padding-bottom: 4pt">&nbsp;</TD>
      <TD STYLE="border-bottom: Black 4pt double; text-align: left">$</TD><TD STYLE="border-bottom: Black 4pt double; text-align: right">69,597,000</TD><TD STYLE="padding-bottom: 4pt; text-align: left"><SUP>(3)</SUP></TD><TD STYLE="padding-bottom: 4pt">&nbsp;</TD>
      <TD STYLE="border-bottom: Black 4pt double; text-align: left">$</TD><TD STYLE="border-bottom: Black 4pt double; text-align: right">7,593.03</TD><TD STYLE="padding-bottom: 4pt; text-align: left">&nbsp;</TD></TR>
  </TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Pursuant to Rule 416 promulgated under the Securities Act of 1933, as amended, there are also registered hereunder such indeterminate number of additional shares as may be issued to prevent dilution resulting from stock splits, stock dividends or similar transactions.</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(2)</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Represents shares issued or issuable pursuant to the INmune Bio, Inc., 2017 Equity Incentive Plan.</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(3)</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Estimated solely for purposes of calculating the registration fee in accordance with Rule 457(c) under the Securities Act of 1933, as amended, using the average of the high and low price as reported on the NASDAQ Capital Market on February 22, 2021.</FONT></TD></TR>
  </TABLE>
  
  <P STYLE="margin: 0">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(4)</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Represents shares issued or issuable pursuant to the INmune Bio, Inc., 2019 Equity Incentive Plan.</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.25in; text-align: center"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.25in; text-align: center"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>PART I</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.25in; text-align: center"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B><BR>
  INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.25in; text-align: center"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">This Registration Statement relates to
  two separate prospectuses.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><U>Section 10(a) Prospectus</U>: Items
  1 and 2, from this page, and the documents incorporated by reference pursuant to Part II, Item 3 of this prospectus, constitute
  a prospectus that meets the requirements of Section 10(a) of the Securities Act of 1933, as amended (the &ldquo;Securities Act&rdquo;).</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><U>Reoffer Prospectus</U>: The material
  that follows Item 2, up to but not including Part II of this Registration Statement, of which the reoffer prospectus is a part,
  constitutes a &ldquo;reoffer prospectus,&rdquo; prepared in accordance with the requirements of Part I of Form S-3 under the Securities
  Act. Pursuant to Instruction C of Form S-8, the reoffer prospectus may be used for reoffers or resales of shares of common stock
  which are deemed to be &ldquo;control securities&rdquo; or &ldquo;restricted securities&rdquo; under the Securities Act that have
  been acquired by the selling stockholders named in the reoffer prospectus.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Item 1.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Plan
  Information.</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">INmune Bio Inc. will provide each participant
  (the &ldquo;Recipient&rdquo;) with documents that contain information related to the INmune Bio Inc. 2017 Equity Incentive Plan
  (the &ldquo;2017 Plan&rdquo;) and the INmune Bio Inc. 2019 Equity Incentive Plan (the &ldquo;2019 Plan&rdquo;), and other information
  including, but not limited to, the disclosure required by Item 1 of Form S-8, which information is not filed as a part of this
  Registration Statement on Form S-8. The foregoing information and the documents incorporated by reference in response to Item 3
  of Part II of this Registration Statement taken together constitute a prospectus that meets the requirements of Section 10(a) of
  the Securities Act. A Section 10(a) prospectus will be given to each Recipient who receives shares of common stock covered by this
  Registration Statement, in accordance with Rule 428(b)(1) under the Securities Act.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Item 2.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Registrant
  Information and Employee Plan Annual Information.</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">We will provide to each Recipient a written
  statement advising it of the availability of documents incorporated by reference in Item 3 of Part II of this Registration Statement
  and of documents required to be delivered pursuant to Rule 428(b) under the Securities Act without charge and upon written or oral
  notice by contacting:</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center; background-color: white">INmune Bio, Inc.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center; background-color: white">1200 Prospect Street,
  Suite 525,</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center; background-color: white">La Jolla, CA 92037</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center; background-color: white">Attention: Corporate
  Secretary</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Telephone: 585-359-5900</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center; background-color: white">&nbsp;&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Information required by Part I to be
  contained in Section 10(a) prospectus is omitted from the Registration Statement in accordance with Rule 428 under the Securities
  Act of 1933, and Note to Part I of Form S-8.</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"></P>
  
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>REOFFER PROSPECTUS</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>INmune Bio Inc. </B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>3,700,000 Shares of Common Stock</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Issued or issuable under certain awards
  granted under the Plans</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">This reoffer prospectus relates to the
  sale of 3,700,000 shares of our common stock that may be offered and resold from time to time by the selling stockholders identified
  in this prospectus for their own account. Such shares have been or may be acquired in connection with awards granted under the
  INmune Bio Inc. 2017 Equity Incentive Plan (the &ldquo;2017 Plan&rdquo;) and the INmune Bio Inc. 2019 Equity Inventive Plan (the
  &ldquo;2019 Plan,&rdquo; and collectively with the 2017 Plan, the &ldquo;Plans&rdquo;). It is anticipated that the selling stockholders
  will offer shares for sale at prevailing prices on the NASDAQ Capital Market on the date of sale. We will receive no part of the
  proceeds from sales made under this reoffer prospectus. The selling stockholders will bear all sales commissions and similar expenses.
  Any other expenses incurred by us in connection with the registration and offering and not borne by the selling stockholders will
  be borne by us.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">This reoffer prospectus has been prepared
  for the purposes of registering the shares under the Securities Act of 1933, as amended (the &ldquo;Securities Act&rdquo;) to allow
  for future sales by selling stockholders on a continuous or delayed basis to the public without restriction.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">The selling stockholders and any brokers
  executing selling orders on their behalf may be deemed to be &ldquo;underwriters&rdquo; within the meaning of the Securities Act,
  in which event commissions received by such brokers may be deemed to be underwriting commissions under the Securities Act.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Our common stock is quoted on the NASDAQ
  Capital Market under the symbol &ldquo;INMB.&rdquo; The last reported sale price of our common stock on the NASDAQ Capital Market
  on February 22, 2021, was $18.04 per share.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">We are an &ldquo;emerging growth company&rdquo;
  as that term is used in the Jumpstart Our Business Startups Act of 2012, or the JOBS Act, and, as such, have elected to comply
  with certain reduced public company reporting requirements for this prospectus supplement, the accompanying prospectus and our
  filings with the Securities and Exchange Commission.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 24.5pt"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Investing in our common stock involves a high degree of risk.
  See &ldquo;Risk Factors&rdquo; beginning on page&nbsp;[S-5] of this prospectus supplement and page&nbsp;5 of the accompanying prospectus.
  </B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;<B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Neither the Securities and Exchange Commission nor any state
  securities commission has approved or disapproved of these securities or determined if this prospectus supplement is truthful or
  complete. Any representation to the contrary is a criminal offense. </B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>
  
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      <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">The date of this prospectus is March 22, 2021.&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><U>TABLE OF CONTENTS </U></B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 93%">&nbsp;</TD>
      <TD STYLE="width: 7%; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B><U>Page</U></B></FONT><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="vertical-align: top; background-color: #CCEEFF">
      <TD><A HREF="#a_002"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Prospectus Summary&nbsp;</FONT></A></TD>
      <TD STYLE="text-align: center">6</TD></TR>
  <TR STYLE="vertical-align: top; background-color: white">
      <TD><A HREF="#a_003"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Risk Factors</FONT></A></TD>
      <TD STYLE="text-align: center">8</TD></TR>
  <TR STYLE="vertical-align: top; background-color: #CCEEFF">
      <TD><A HREF="#a_004"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Cautionary Note Regarding Forward Looking Statements</FONT></A></TD>
      <TD STYLE="text-align: center">9</TD></TR>
  <TR STYLE="vertical-align: top; background-color: white">
      <TD><A HREF="#a_005"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Use of Proceeds</FONT></A></TD>
      <TD STYLE="text-align: center">9</TD></TR>
  <TR STYLE="vertical-align: top; background-color: #CCEEFF">
      <TD><A HREF="#a_006"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Selling Stockholders</FONT></A></TD>
      <TD STYLE="text-align: center">9</TD></TR>
  <TR STYLE="vertical-align: top; background-color: white">
      <TD><A HREF="#a_007"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Plan of Distribution</FONT></A></TD>
      <TD STYLE="text-align: center">11</TD></TR>
  <TR STYLE="vertical-align: top; background-color: #CCEEFF">
      <TD><A HREF="#a_008"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Legal Matters</FONT></A></TD>
      <TD STYLE="text-align: center">14</TD></TR>
  <TR STYLE="vertical-align: top; background-color: white">
      <TD><A HREF="#a_009"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Experts</FONT></A></TD>
      <TD STYLE="text-align: center">14</TD></TR>
  <TR STYLE="vertical-align: top; background-color: #CCEEFF">
      <TD><A HREF="#a_010"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Incorporation of Certain Documents by Reference</FONT></A></TD>
      <TD STYLE="text-align: center">14</TD></TR>
  <TR STYLE="vertical-align: top; background-color: white">
      <TD><A HREF="#a_011"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Disclosure of Commission Position on Indemnification For Securities Act Liabilities</FONT></A></TD>
      <TD STYLE="text-align: center">15</TD></TR>
  <TR STYLE="vertical-align: top; background-color: #CCEEFF">
      <TD><A HREF="#a_012"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Additional Information Available to You </FONT></A></TD>
      <TD STYLE="text-align: center">16</TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0.5in; text-align: justify">NO PERSON HAS BEEN AUTHORIZED TO GIVE
  ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE CONTAINED IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFERING
  MADE HEREBY, AND, IF GIVEN OR MADE, SUCH INFORMATION OR REPRESENTATION MUST NOT BE RELIED UPON AS HAVING BEEN AUTHORIZED BY THE
  COMPANY OR ANY OTHER PERSON. NEITHER THE DELIVERY OF THIS PROSPECTUS NOR ANY SALE MADE HEREUNDER SHALL UNDER ANY CIRCUMSTANCES
  CREATE ANY IMPLICATION THAT THERE HAS BEEN NO CHANGE IN THE AFFAIRS OF THE COMPANY SINCE THE DATE HEREOF. THIS PROSPECTUS DOES
  NOT CONSTITUTE AN OFFER TO SELL OR A SOLICITATION OF AN OFFER TO BUY ANY SECURITIES OFFERED HEREBY BY ANYONE IN ANY JURISDICTION
  IN WHICH SUCH OFFER OR SOLICITATION IS NOT AUTHORIZED OR IN WHICH THE PERSON MAKING SUCH OFFER OR SOLICITATION IS NOT QUALIFIED
  TO DO SO OR TO ANY PERSON TO WHOM IT IS UNLAWFUL TO MAKE SUCH OFFER OR SOLICITATION.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0.5in; text-align: justify"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"></P>
  
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_002"></A>PROSPECTUS SUMMARY</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">This summary highlights information contained
  elsewhere in this prospectus. You should read the entire prospectus carefully, including the section entitled &ldquo;Risk Factors&rdquo;
  before deciding to invest in our common stock. In this prospectus, the &ldquo;Company,&rdquo; &ldquo;we,&rdquo; &ldquo;us&rdquo;
  and &ldquo;our&rdquo; refer to INmune Bio Inc. and its subsidiaries.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Company Overview</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">We are a clinical-stage immunotherapy company
  focused on developing drugs that may reprogram the patient&rsquo;s innate immune system to treat disease. We believe this may be
  done by targeting cells of the innate immune system that cause acute and chronic inflammation and are involved in the immune dysfunction
  associated with chronic diseases such as cancer, neurodegenerative, metabolic and infectious diseases. The Company has two therapeutic
  platforms &ndash; dominant-negative TNF platform (&ldquo;DN-TNF&rdquo;) and the Natural Killer (&ldquo;NK&rdquo;) platform. The
  DN-TNF platform neutralizes soluble TNF (&ldquo;sTNF&rdquo;) without affecting trans-membrane TNF (&ldquo;tmTNF&rdquo;) or the
  receptors TNFR1 and TNFR2. This unique biologic mechanism differentiates the DN-TNF drugs from currently approved non-selective
  TNF inhibitors that inhibit the function of both sTNF and tmTNF. Protecting the function of tmTNF while neutralizing the function
  of sTNF is a potent anti-inflammatory drug that does not cause immunosuppression or demyelination. Currently approved non-selective
  TNF inhibitors are approved to treat autoimmune disease, however they are contraindicated in patients with infection, cancer and
  neurologic diseases because they increase the risk of infection, cancer and demyelinating neurologic diseases, respectively, because
  of off-target effects on inhibiting tmTNF. The NK platform targets the dysfunctional natural killer cells (&ldquo;NK cells&rdquo;)
  in patients with cancer. NK cells are part of the normal immunologic response to cancer with important roles in immunosurveillance
  to prevent cancer and in preventing relapse by clearing residual disease. Residual disease is the cancer left behind, often undetected,
  that can grow and cause relapse. The NK cells of cancer patients have the ability to kill cancer cells but are not effective because
  cancer cells mutate to evade NK cell immune surveillance. INKmune provides the missing signals needed to prime NK cells to overcome
  the immune evasion mutation to allow NK cells to kill the cancer cell. We believe INKmune is best used to eliminate residual disease
  after the patient has completed other cancer therapies. Both the DN-TNF platform and the INKmune platform can be used to treat
  multiple diseases. The DN-TNF platform will be used as an immunotherapy for the treatment of cancer, neurodegenerative, metabolic
  and infectious diseases. INKmune is being developed to treat NK sensitive hematologic malignancies and solid tumors.&nbsp; &nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">We believe our DN-TNF platform can be used
  to reverse resistance in immunotherapy, to target glial activation to prevent progression of Alzheimer&rsquo;s disease (&ldquo;AD&rdquo;),
  to target neuroinflammation in treatment resistant depression (&ldquo;TRD&rdquo;), to target intestinal leak and inflammation to
  treat non-alcoholic steatohepatitis (&ldquo;NASH&rdquo;) and to treat complications of the cytokine storm associated with COVID-19
  infection. The drug is named differently for each indication; INB03, XPro1595, LIVNate and Quellor, respectively, but it is the
  same drug product. In each case, we believe neutralizing sTNF is a cornerstone to the treatment of each of these diseases. As an
  immunotherapy for cancer, we are using INB03 to neutralize sTNF produced by HER2+ trastuzumab resistant breast cancers to reverse
  resistance to therapy. sTNF causes an up-regulation of MUC4 expression that causes steric hindrance of trastuzumab binding to the
  HER2/Neu receptor on HER2+ breast cancer cells. Without binding, trastuzumab is not effective. In addition, INB03 changes the immunobiology
  of the tumor microenvironment by decreasing the number of immunosuppressive myeloid cells, both myeloid derived suppressor cells
  and tumor active macrophages, and increasing the number of cytotoxic lymphocytes in the TME. The Company has completed an open
  label dose escalation trial in cancer patients with metastatic solid tumors that have failed multiple lines of therapy. The trial
  informs the design of the Phase II trial by demonstrating that INB03 was safe and well tolerated, defined the dose of INB03 to
  carry into Phase II trials, and demonstrated a pharmacodynamic end-point. A Phase II trial is planned in women with advanced HER2+
  breast cancer with metastasis.&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>
  
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Likewise, we believe the DN-TNF platform
  can be used to treat selected neurodegenerative diseases. XPro1595 is being used to treat patients with Alzheimer&rsquo;s disease
  in a Phase I trial partially funded by a Part-the-Clouds Award from the Alzheimer&rsquo;s Association. XPro1595 targets activated
  microglia and astrocytes of the brain that produce sTNF that promotes nerve cell loss and synaptic dysfunction, key elements in
  the development of dementia. In animal models, elimination of sTNF prevents nerve cell dysfunction and reverses synaptic pruning.
  The Phase I trial in patients with biomarkers of inflammation with AD is enrolling patients. The open label, dose escalation trial
  is designed to demonstrate that XPro1595 decreases neuroinflammation in patients with AD. This end-points of the trial are measures
  of neuroinflammation and neurodegeneration in blood and cerebral spinal fluid, measures of neuroinflammation by MRI by measuring
  white matter free water and breath by measuring volatile organic compounds in exhaled breath and by monitoring neuropsychiatric
  symptoms known to be associated with neuroinflammation including depression, apathy, aggression, hallucinations and sleep disorders.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">In addition, we believe the DN-TNF platform
  can be used to treat selected metabolic diseases. LIVNate is being developed to treat NASH. NASH is a pleiotropic disease caused
  by a complex mix of metabolic, inflammatory and fibrotic pathophysiology. We believe targeting inflammation caused by intestinal
  leak, mesenteric and peripheral fat will prevent lipotoxicity, hepatic stellate cell activation and hepatocyte death that causes
  fibrosis and liver dysfunction associated with advanced disease. sTNF is elevated in obesity and is believed to cause intestinal
  leak. Intestinal leak combined with cytokines coming from mesenteric fat may dramatically increase the concentration of inflammatory
  cytokines in portal blood destined for the liver. The cytokine load contributes to the development of non-alcoholic fatty liver
  disease (&ldquo;NAFLD&rdquo;) and progression to NASH. LIVNate, by neutralizing sTNF improves insulin sensitivity, decreases the
  inflammation in peripheral and mesenteric fat and may also seal the intestinal leak. This combination prevents development of NAFLD
  or NASH in animal models. The Company is planning a Phase II open label randomized study using non-invasive measures to enroll
  patients with NASH in a study using a fixed dose of LIVNate delivered as a once a week sub-cutaneous injection.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">We also believe the DN-TNF platform may
  be used to treat the complications associated with the cytokine storm caused by coronavirus disease 2019 (&ldquo;COVID-19&rdquo;).
  Three inflammatory cytokines make up the cytokine storm associated with COVID19 infection &ndash; sTNF, IL-6 and IL-1&beta;. Targeting
  sTNF with Quellor may have advantages because IL-6 and IL-1 expression occur after sTNF expression; sTNF promotes endothelial activation
  causing expression of proteins that promote trafficking of immune cells from the blood vessel to the tissue and expression of Tissue
  Factor that stimulates the coagulopathy that is a prominent pathology of COVID-19 infection. The Company plans a Phase II trial
  in patients with symptomatic COVID-19 infection and hypoxia. The goal of the study is to prevent the catastrophic complications
  of advanced COVID-19 infection including one or more of the need for mechanical ventilation, new onset of cardiovascular, neurologic
  or thromboembolic disease, admission to an intensive care unit or death. The randomized trial will treat patients requiring hospitalization
  because of their disease.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Effective therapy for TRD is a large unmet
  need. Twenty percent of patients with a Major Depressive Disorder have TRD. Once third of TRD patients have peripheral biomarkers
  to inflammation (elevated CRP). This is a large patient population. The role of TNF and anti-TNF therapeutics was explored in a
  small open label clinical trial by Prof. Andrew Miller, MD of Emory University demonstrated the patients have elevated TNF levels
  and treatment with infliximab treated their depression (Miller, 2011). The Company received a $2.9M USD award from the National
  Institute of Mental Health (&ldquo;NIMH&rdquo;) to treat TRD with XPro1595. The blinded, randomized Phase II trial will use a biomarkers
  of peripheral inflammation to select patients with TRD for enrollment. Patients will be treated for 6 weeks. Primary end-points
  include both clinical and neuroimaging measures. The final trial design has is ongoing and discussions with the FDA are not complete.
  The Company anticipates receiving authorization to initiate the clinical trial in the second half of 2021.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">We believe that INKmune improves the ability
  of the patient&rsquo;s own NK cells to attack their tumor. INKmune interacts with the patient&rsquo;s NK cells to convert them
  from inert resting NK cells that ignores the cancer into primed NK cells that kill the cancer cell. INKmune is a replication incompetent
  proprietary cell line we have named INB16 that is given to the patient after determining that i) the patient has adequate NK cells
  in their circulation and ii) those NK cells are functional when exposed to INKmune in vitro. INKmune is designed to be given to
  patients after their immune system has recovered after cytotoxic chemotherapy to target the residual disease the remains after
  treatment with cytotoxic therapy. INKmune can be used to treat numerous hematologic malignancies and solid tumors including leukemia,
  multiple myeloma, lymphoma, lung, ovary, breast, renal and prostate cancer. The Company plans Phase I trials using INKmune to treat
  patients with high risk MDS, a form of leukemia and women with relapsed refractory ovarian.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>
  
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Corporate Information</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Our principal executive offices are located
  at 1200 Prospect Street, Suite 525, La Jolla, California 92037. Our telephone number is (858) 964-3720. We maintain an Internet
  website at www.inmunebio.com. The information contained on, connected to or that can be accessed via our website is not part of
  this prospectus. We have included our website address in this prospectus as an inactive textual reference only and not as an active
  hyperlink</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="background-color: white"><B>About
  This Offering</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="background-color: white">This
  offering relates to the resale by the selling stockholders of up to 3,700,000 shares of common stock issued or issuable upon exercise
  of options issued pursuant to grants made pursuant to our 2017 Plan and 2019 Plan. </FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><A NAME="a_003"></A><B>RISK FACTORS</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Investing in our securities involves a
  high degree of risk. Before making an investment decision, you should consider carefully the risks, uncertainties and other factors
  described in our most recent Annual Report on Form 10-K, as supplemented and updated by subsequent quarterly reports on Form 10-Q
  and current reports on Form 8-K that we have filed or will file with the SEC</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; background-color: white">You should carefully
  consider the factors discussed in Part&nbsp;I, Item&nbsp;1A. &ldquo;Risk Factors&rdquo; in our annual report on Form&nbsp;10-K
  for the&nbsp;year ended December&nbsp;31, 2020. Except as set forth below, there have been no material changes from those risk
  factors. The risks discussed in our 2020 annual report and described below could materially affect our business, financial condition
  and future results.&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; background-color: white">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>An occurrence of an uncontrollable event
  such as the COVID-19 pandemic may negatively affect our operations and ability to raise capital.</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">The occurrence of an uncontrollable event
  such as the COVID-19 pandemic may negatively affect our operations. A pandemic typically results in social distancing, travel bans
  and quarantine, and this may limit access to our facilities, customers, management, support staff and professional advisors. These
  factors, in turn, may impact our operations and financial condition. Also, the pandemic may hamper our efforts to comply with our
  filing obligations with the Securities and Exchange Commission. We cannot presently predict the scope and severity of any potential
  business shutdowns or disruptions, but if we or any of the third parties with whom we engage, including the suppliers, clinical
  trial sites, regulators and other third parties with whom we conduct business, were to experience shutdowns or other business disruptions,
  our ability to conduct our business in the manner and on the timelines presently planned could be materially and negatively impacted.
  Furthermore, if any of our key employees became ill or die as a result of COVID-19, it could negatively impact our business.&nbsp;
  It is also possible that global health concerns such as this one could disproportionately impact the clinical sites in which we
  conduct any of our clinical trials, which could have a material adverse effect on our business and our results of operation and
  financial condition.&nbsp;The COVID-19 pandemic, may also negatively impact the Company&rsquo;s ability to raise capital.&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"></P>
  
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_004"></A>CAUTIONARY NOTE REGARDING FORWARD-LOOKING
  STATEMENTS</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">This prospectus and the documents and information
  incorporated by reference in this prospectus contain certain forward-looking statements within the meaning of the Private Securities
  Litigation Reform Act of 1995. For this purpose, any statements contained in this prospect and the documents and information incorporated
  by reference in this prospectus that are not statements of historical fact may be deemed to be forward-looking statements. Without
  limiting the foregoing, words such as &ldquo;may,&rdquo; &ldquo;will,&rdquo; &ldquo;expect,&rdquo; &ldquo;believe,&rdquo; &ldquo;anticipate,&rdquo;
  &ldquo;estimate&rdquo; or &ldquo;continue&rdquo; or comparable terminology are intended to identify forward-looking statements.
  These statements by their nature involve substantial risks and uncertainties, and actual results may differ materially depending
  on a variety of factors, many of which are not within our control. These factors include but are not limited to economic conditions
  generally and in the industries in which we may participate; competition within our chosen industry, including competition from
  much larger competitors; technological advances and failure to successfully develop business relationships.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>
  
  
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_005"></A>USE OF PROCEEDS</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="background-color: white">We will not receive any
  proceeds from the sale of shares of common stock offered by the selling stockholders.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_006"></A>SELLING STOCKHOLDERS </B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="background-color: white">This
  offering relates to the resale by the selling stockholders who have received or acquired, or may hereafter receive or acquire,
  the shares pursuant to the Plans. The selling stockholders may resell all, a portion, or none of the shares of common stock from
  time to time.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">The following table sets forth, based on
  information provided to us by the selling stockholders or known to us, the name of each selling stockholder, the nature of any
  position, office or other material relationship, if any, which the selling stockholder has had, within the past three years, with
  us or with any of our predecessors or affiliates, and the number of shares of our common stock beneficially owned by the selling
  stockholder before this offering.&nbsp;Except as otherwise indicated, the selling stockholders are past or present employees or
  consultants of the Company. The number of shares owned are those beneficially owned, as determined under the rules of the SEC,
  and the information is not necessarily indicative of beneficial ownership for any other purpose.&nbsp;Under these rules, beneficial
  ownership includes any shares of common stock as to which a person has sole or shared voting power or investment power and any
  shares of common stock which the person has the right to acquire within 60 days through the exercise of any option, warrant or
  right, through conversion of any security or pursuant to the automatic termination of a power of attorney or revocation of a trust,
  discretionary account or similar arrangement. None of the selling stockholders is a broker-dealer or an affiliate of a broker-dealer.
  Percentage of ownership is based on 14,932,638 shares of common stock outstanding on March 4, 2021.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">We have assumed all shares of common stock
  reflected on the table will be sold from time to time in the offering covered by this prospectus.&nbsp;Because the selling stockholders
  may offer all or any portion of the shares of common stock listed in the table below, no estimate can be given as to the amount
  of those shares of common stock covered by this prospectus that will actually be held by the selling stockholders upon the termination
  of the offering. Selling stockholders may choose not to sell any of the shares of common stock registered herein.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"></P>
  
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: bottom">
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD COLSPAN="6" STYLE="border-bottom: black 1pt solid">
          <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>Number of Shares</B></P>
          <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>Beneficially Owned Prior to Offering (1)</B></P></TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; text-align: center"><FONT STYLE="font-size: 10pt"><B>Number of Shares Being</B></FONT></TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD COLSPAN="6" STYLE="text-align: center; border-bottom: Black 1pt solid; vertical-align: bottom">
          <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>
          <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>Number of Shares Beneficially Owned After
          Offering&nbsp;</B></P>
          <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B></B></P></TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom">
      <TD STYLE="border-bottom: black 1pt solid"><FONT STYLE="font-size: 10pt"><B>Selling Stockholder</B></FONT></TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="border-bottom: black 1pt solid; text-align: center"><FONT STYLE="font-size: 10pt"><B>Position</B></FONT></TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; text-align: center"><FONT STYLE="font-size: 10pt"><B>Number</B></FONT></TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; text-align: center"><FONT STYLE="font-size: 10pt"><B>Percent (%)</B></FONT></TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; text-align: center"><FONT STYLE="font-size: 10pt"><B>Offered</B></FONT></TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; text-align: center"><FONT STYLE="font-size: 10pt"><B>Number</B></FONT></TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD COLSPAN="2" STYLE="border-bottom: Black 1pt solid; text-align: center"><FONT STYLE="font-size: 10pt"><B>Percent (%)</B></FONT></TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: #CCEEFF">
      <TD STYLE="width: 10%"><FONT STYLE="font-size: 10pt">Raymond J. Tesi</FONT></TD>
      <TD STYLE="width: 1%">&nbsp;</TD>
      <TD STYLE="width: 15%"><FONT STYLE="font-size: 10pt">President, CEO and Director</FONT></TD>
      <TD STYLE="width: 1%">&nbsp;</TD>
      <TD STYLE="width: 1%">&nbsp;</TD>
      <TD STYLE="width: 12%; text-align: right"><FONT STYLE="font-size: 10pt">2,082,594</FONT></TD>
      <TD STYLE="width: 1%">&nbsp;</TD>
      <TD STYLE="width: 1%">&nbsp;</TD>
      <TD STYLE="width: 1%">&nbsp;</TD>
      <TD STYLE="width: 12%; text-align: right"><FONT STYLE="font-size: 10pt">13.9</FONT></TD>
      <TD STYLE="width: 1%"><FONT STYLE="font-size: 10pt">%</FONT></TD>
      <TD STYLE="width: 1%">&nbsp;</TD>
      <TD STYLE="width: 1%">&nbsp;</TD>
      <TD STYLE="width: 12%; text-align: right"><FONT STYLE="font-size: 10pt">541,661</FONT></TD>
      <TD STYLE="width: 3%"><FONT STYLE="font-size: 10pt">(2)</FONT></TD>
      <TD STYLE="width: 1%">&nbsp;</TD>
      <TD STYLE="width: 1%">&nbsp;</TD>
      <TD STYLE="width: 12%; text-align: right"><FONT STYLE="font-size: 10pt">1,540,933</FONT></TD>
      <TD STYLE="width: 1%">&nbsp;</TD>
      <TD STYLE="width: 1%">&nbsp;</TD>
      <TD STYLE="width: 1%">&nbsp;</TD>
      <TD STYLE="width: 9%; text-align: right"><FONT STYLE="font-size: 10pt">10.3</FONT></TD>
      <TD STYLE="width: 1%"><FONT STYLE="font-size: 10pt">%</FONT></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: white">
      <TD><FONT STYLE="font-size: 10pt">David Moss</FONT></TD>
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-size: 10pt">CFO, Treasurer and Secretary</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">1,765,078</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">11.8</FONT></TD>
      <TD><FONT STYLE="font-size: 10pt">%</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">541,661</FONT></TD>
      <TD><FONT STYLE="font-size: 10pt">(3)</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">1,223,417</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">8.2</FONT></TD>
      <TD><FONT STYLE="font-size: 10pt">%</FONT></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: #CCEEFF">
      <TD><FONT STYLE="font-size: 10pt">Mark Lowdell</FONT></TD>
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-size: 10pt">CSO</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">1,991,251</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">13.3</FONT></TD>
      <TD><FONT STYLE="font-size: 10pt">%</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">485,000</FONT></TD>
      <TD><FONT STYLE="font-size: 10pt">(4)</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">1,506,251</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">10.1</FONT></TD>
      <TD><FONT STYLE="font-size: 10pt">%</FONT></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: white">
      <TD><FONT STYLE="font-size: 10pt">Christopher Barnum</FONT></TD>
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-size: 10pt">Head of Neuroscience</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">94,467</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">*</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">94,467</FONT></TD>
      <TD><FONT STYLE="font-size: 10pt">(5)</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">-&nbsp;&nbsp;</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">*</FONT></TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: #CCEEFF">
      <TD><FONT STYLE="font-size: 10pt">Josh Schoonover</FONT></TD>
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-size: 10pt">Assoc. General Counsel</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">85,000</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">*</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">85,000</FONT></TD>
      <TD><FONT STYLE="font-size: 10pt">(6)</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">-&nbsp;&nbsp;</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">*</FONT></TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: white">
      <TD><FONT STYLE="font-size: 10pt">Cory Ellspermann</FONT></TD>
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-size: 10pt">Controller and VP of Finance</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">30,123</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">*</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">30,123</FONT></TD>
      <TD><FONT STYLE="font-size: 10pt">(7)</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">-&nbsp;&nbsp;</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">*</FONT></TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: #CCEEFF">
      <TD><FONT STYLE="font-size: 10pt">Scott Juda</FONT></TD>
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-size: 10pt">Director</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">187,831</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">1.3</FONT></TD>
      <TD><FONT STYLE="font-size: 10pt">%</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">160,331</FONT></TD>
      <TD><FONT STYLE="font-size: 10pt">(8)</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">27,500</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">*</FONT></TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: white">
      <TD><FONT STYLE="font-size: 10pt">Timothy Schroeder</FONT></TD>
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-size: 10pt">Director</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">326,998</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">2.2</FONT></TD>
      <TD><FONT STYLE="font-size: 10pt">%</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">160,331</FONT></TD>
      <TD><FONT STYLE="font-size: 10pt">(9)</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">166,667</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">1.1</FONT></TD>
      <TD><FONT STYLE="font-size: 10pt">%</FONT></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: #CCEEFF">
      <TD><FONT STYLE="font-size: 10pt">J. Kelly Ganjei</FONT></TD>
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-size: 10pt">Director</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">160,331</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">1.1</FONT></TD>
      <TD><FONT STYLE="font-size: 10pt">%</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">160,331</FONT></TD>
      <TD><FONT STYLE="font-size: 10pt">(10)</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">*</FONT></TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: white">
      <TD><FONT STYLE="font-size: 10pt">Edgardo Baracchini</FONT></TD>
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-size: 10pt">Director</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">52,331</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">*</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">52,331</FONT></TD>
      <TD><FONT STYLE="font-size: 10pt">(11)</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">*</FONT></TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: #CCEEFF">
      <TD><FONT STYLE="font-size: 10pt">Marcia Allen</FONT></TD>
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-size: 10pt">Director</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">52,331</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">*</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">52,331</FONT></TD>
      <TD><FONT STYLE="font-size: 10pt">(12)</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: right"><FONT STYLE="font-size: 10pt">*</FONT></TD>
      <TD>&nbsp;</TD></TR>
  </TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"></P>
  
  
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="background-color: white">*
  Less than 1%</FONT></P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="background-color: white">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="background-color: white">(1)</FONT> The securities
  &ldquo;beneficially owned&rdquo; by a person are determined in accordance with the definition of &ldquo;beneficial ownership&rdquo;
  set forth in the rules and regulations promulgated under the Exchange Act, and accordingly, may include securities owned by and
  for, among others, the spouse and/or minor children of an individual and any other relative who has the same home as such individual,
  as well as other securities as to which the individual has or shares voting or investment power or which such person has the right
  to acquire within 60 days of March 4, 2021 pursuant to the exercise of options, or otherwise. &nbsp;Beneficial ownership may be
  disclaimed as to certain of the securities.</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="background-color: white">(2)</FONT> Includes:
  (a) options to purchase 400,000 shares of common stock exercisable by Mr. Tesi at an exercise price of $7.80 per share; and (b)
  options to purchase 141,661 shares of common stock exercisable by Mr. Tesi at an exercise price of $3.91 per share.</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="background-color: white">(3)</FONT> Includes:
  (a) options to purchase 400,000 shares of common stock exercisable by Mr. Moss at an exercise price of $7.80 per share; and (b)
  options to purchase 141,661 shares of common stock exercisable by Mr. Moss at an exercise price of $3.91 per share.</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="background-color: white">(4)</FONT> Includes:
  (a) options to purchase 400,000 shares of common stock exercisable by Mr. Lowdell at an exercise price of $7.80 per share; and
  (b) options to purchase 85,000 shares of common stock exercisable by Mr. Lowdell at an exercise price of $3.91 per share.</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="background-color: white">(5) </FONT>Includes
  options to purchase 94,467 shares of common stock exercisable by Mr. Barnum at an exercise price of $3.91 per share.</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <!-- Field: Page; Sequence: 10 -->
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  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;&nbsp;</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="background-color: white">(6)</FONT> Includes
  options to purchase 85,000 shares of common stock exercisable by Mr. Schoonover at an exercise price of $3.91 per share.</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="background-color: white">(7)</FONT> Includes
  options to purchase 30,123 shares of common stock exercisable by Mr. Ellspermann at an exercise price of $3.91 per share.</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="background-color: white">(8)</FONT> Includes:
  (a) options to purchase 108,000 shares of common stock exercisable by Mr. Juda at an exercise price of $7.80 per share; (b) options
  to purchase 51,000 shares of common stock exercisable by Mr. Juda at an exercise price of $3.91 per share; and (c) options to purchase
  1,331 shares of common stock exercisable by Mr. Juda at an exercise price of $24.82 per share.</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="background-color: white">(9)</FONT> Includes:
  (a) options to purchase 108,000 shares of common stock exercisable by Mr. Schroeder at an exercise price of $7.80 per share; (b)
  options to purchase 51,000 shares of common stock exercisable by Mr. Schroeder at an exercise price of $3.91 per share; and (c)
  options to purchase 1,331 shares of common stock exercisable by Mr. Schroeder at an exercise price of $24.82 per share.</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="background-color: white">(10)</FONT> Includes:
  (a) options to purchase 108,000 shares of common stock exercisable by Mr. Ganjei at an exercise price of $7.80 per share; (b) options
  to purchase 51,000 shares of common stock exercisable by Mr. Ganjei at an exercise price of $3.91 per share; and (c) options to
  purchase 1,331 shares of common stock exercisable by Mr. Ganjei at an exercise price of $24.82 per share.</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="background-color: white">(11)</FONT> Includes:
  (a) options to purchase 51,000 shares of common stock exercisable by Mr. Baracchini at an exercise price of $3.91 per share; and
  (b) options to purchase 1,331 shares of common stock exercisable by Mr. Baracchini at an exercise price of $24.82 per share.</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="background-color: white">(12)</FONT> Includes:
  (a) options to purchase 51,000 shares of common stock exercisable by Mrs. Allen at an exercise price of $3.91 per share; and (b)
  options to purchase 1,331 shares of common stock exercisable by Mrs. Allen at an exercise price of $24.82 per share.</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0"><B><A NAME="a_007"></A>PLAN OF DISTRIBUTION</B></P>
  
  <P STYLE="font: 10pt/107% Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;<B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Timing of Sales</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="background-color: white">The
  selling stockholders may offer and sell the shares covered by this prospectus at various times. The selling stockholders will act
  independently of our company in making decisions with respect to the timing, manner and size of each sale.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">To our knowledge, no selling stockholder
  has any agreement or understanding, directly or indirectly, with any person to resell the shares of common stock covered by this
  prospectus.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B></B></P>
  
  <!-- Field: Page; Sequence: 11 -->
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      <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
      <!-- Field: /Page -->
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>&nbsp;&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Offering Price</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">The sales price offered by the selling
  stockholders to the public may be:</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 48px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">1.</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">the market price prevailing at the time of sale;</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 50pt; text-align: justify">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 48px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">a price related to such prevailing market price; or</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 48px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">such other price as the selling stockholders determine from time to time.</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Manner of Sale </B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">The shares of common stock may be sold
  by means of one or more of the following methods:</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 48px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">1.</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">a block trade in which the broker-dealer so engaged will attempt to sell the shares of common stock as agent, but may position and resell a portion of the block as principal to facilitate the transaction;</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 50pt; text-align: justify">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 48px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">purchases by a broker-dealer as principal and resale by that broker-dealer for its account pursuant to this prospectus;</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 48px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">ordinary brokerage transactions in which the broker solicits purchasers;</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 48px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">4.</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">through options, swaps or derivatives;</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 48px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">in transactions to cover short sales;</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 48px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">6.</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">privately negotiated transactions; or</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 48px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">7.</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">in a combination of any of the above methods.</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">The selling stockholders may sell their
  shares of common stock directly to purchasers or may use brokers, dealers, underwriters or agents to sell their shares of common
  stock. Brokers or dealers engaged by the selling stockholders may arrange for other brokers or dealers to participate. Brokers
  or dealers may receive commissions, discounts or concessions from the selling stockholders, or, if any such broker-dealer acts
  as agent for the purchaser of shares of common stock, from the purchaser in amounts to be negotiated immediately prior to the sale.
  The compensation received by brokers or dealers may, but is not expected to, exceed that which is customary for the types of transactions
  involved.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Broker-dealers may agree with a selling
  stockholder to sell a specified number of shares of common stock at a stipulated price per common share, and, to the extent the
  broker-dealer is unable to do so acting as agent for a selling stockholder, to purchase as principal any unsold shares of common
  stock at the price required to fulfill the broker-dealer commitment to the selling stockholder.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Broker-dealers who acquire shares of common
  stock as principal may thereafter resell the shares of common stock from time to time in transactions, which may involve block
  transactions and sales to and through other broker-dealers, including transactions of the nature described above, on the NASDAQ
  Capital Market or otherwise at prices and on terms then prevailing at the time of sale, at prices then related to the then-current
  market price or in negotiated transactions. In connection with resales of the shares of common stock, broker-dealers may pay to
  or receive from the purchasers of shares commissions as described above.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"></P>
  
  <!-- Field: Page; Sequence: 12 -->
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      <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">If the selling stockholders enter into
  arrangements with brokers or dealers, as described above, we are obligated to file a post-effective amendment to this registration
  statement disclosing such arrangements, including the names of any broker-dealers acting as underwriters.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">The selling stockholders and any broker-dealers
  or agents that participate with the selling stockholders in the sale of the shares of common stock may be deemed to be &ldquo;underwriters&rdquo;
  within the meaning of the Securities Act. In that event, any commissions received by broker-dealers or agents and any profit on
  the resale of the shares of common stock purchased by them may be deemed to be underwriting commissions or discounts under the
  Securities Act.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Sales Pursuant to Rule 144</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Any shares of common stock covered by this
  prospectus which qualify for sale pursuant to Rule 144 under the Securities Act may be sold under Rule 144 rather than pursuant
  to this prospectus.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Regulation&nbsp;M</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">The selling stockholders must comply with
  the requirements of the Securities Act and the Securities Exchange Act of 1934, as amended (the &ldquo;Exchange Act&rdquo;) in
  the offer and sale of the common stock. In particular we will advise the selling stockholders that the anti-manipulation rules
  of Regulation&nbsp;M under the Exchange Act may apply to sales of shares of common stock in the market and to the activities of
  the selling stockholders and their affiliates. Regulation&nbsp;M under the Exchange Act prohibits, with certain exceptions, participants
  in a distribution from bidding for, or purchasing for an account in which the participant has a beneficial interest, any of the
  securities that are the subject of the distribution.&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Accordingly, during such times as a selling
  stockholder may be deemed to be engaged in a distribution of the common stock, and therefore be considered to be an underwriter,
  the selling stockholder must comply with applicable law and, among other things:</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 48px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">1.</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">may not engage in any stabilization activities in connection with our common stock;</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.75in; text-align: justify">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 48px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">may not cover short sales by purchasing shares while the distribution is taking place; and</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 48px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">may not bid for or purchase any of our securities or attempt to induce any person to purchase any of our securities other than as permitted under the Exchange Act.</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">In addition, we will make copies of this
  prospectus available to the selling stockholders for the purpose of satisfying the prospectus delivery requirements of the Securities
  Act.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>State Securities Laws</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Under the securities laws of some states,
  the shares of common stock may be sold in such states only through registered or licensed brokers or dealers. In addition, in some
  states the shares of common stock may not be sold unless the shares have been registered or qualified for sale in the state or
  an exemption from registration or qualification is available and is complied with.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Expenses of Registration</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">We are bearing all costs relating to the
  registration of the common stock. The selling stockholders, however, will pay any commissions or other fees payable to brokers
  or dealers in connection with any sale of the common stock.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B></B></P>
  
  <!-- Field: Page; Sequence: 13 -->
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_008"></A>LEGAL MATTERS</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">The validity of the common stock has been
  passed upon by Sichenzia Ross Ference LLP, New York, New York.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_009"></A>EXPERTS</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">The consolidated financial statements of
  INmune Bio Inc. as of and for the years ended December&nbsp;31, 2020 and December 31, 2019 appearing in INmune Bio Inc.&rsquo;s
  Annual Report on Form 10-K for the year ended December&nbsp;31, 2020, have been audited by Marcum LLP, as set forth in its report
  thereon, included therein, and incorporated herein by reference. Such consolidated financial statements are incorporated herein
  by reference in reliance upon such report given on the authority of such firm as experts in accounting and auditing.&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase"><B><A NAME="a_010"></A>INCORPORATION
  OF CERTAIN DOCUMENTS by Reference</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">The Securities and Exchange Commission,
  or SEC, allows us to incorporate by reference certain of our publicly filed documents into this prospectus, which means that such
  information is considered part of this prospectus. Information that we file with the SEC subsequent to the date of this prospectus
  will automatically update and supersede this information. We incorporate by reference the documents listed below and any future
  filings made with the SEC under all documents subsequently filed by us pursuant to Section 13(a), 13(c), 14 or 15(d) of the Exchange
  Act until the selling stockholders have sold all of the shares offered hereby or such shares have been deregistered.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">our Annual Report on Form <A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390021013456/f10k2020_inmunebioinc.htm" STYLE="-sec-extract: exhibit">10-K</A> for the fiscal
      year ended December 31, 2020, filed with the SEC on March 4, 2021;</FONT></TD></TR>
  </TABLE>
  
  <P STYLE="margin: 0">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">our Annual Report on Form <A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020005916/f10k2019_inmunebioinc.htm" STYLE="-sec-extract: exhibit">10-K</A> for the fiscal
      year ended December 31, 2019, filed with the SEC on March 11, 2020;</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">our Quarterly Report on Form <A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020012056/f10q0320_inmunebio.htm" STYLE="-sec-extract: exhibit">10-Q</A> for the period ended March 31, 2020, filed with the SEC May 14, 2020; </FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">our Quarterly Report on Form <A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020020373/f10q0620_inmunebio.htm" STYLE="-sec-extract: exhibit">10-Q</A> for the period ended June 30, 2020, filed with the SEC August 5, 2020;</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">our Quarterly Report on Form <A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020035280/f10q0920_inmunebioinc.htm" STYLE="-sec-extract: exhibit">10-Q</A> for the period ended September 30, 2020, filed with the SEC on November 5, 2020; </FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 2.25pt">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">our Current Reports on Form 8-K or Form 8-K/A
      filed with the SEC on<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020006109/ea119517-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      March 12, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020008917/ea120559-8k_inmunebioinc.htm" STYLE="-sec-extract: exhibit">
      April 9, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020009372/ea120711-8k_inmunebioinc.htm" STYLE="-sec-extract: exhibit">
      April 17, 2020</A>, <A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020009642/ea120866-8k_inmune.htm" STYLE="-sec-extract: exhibit">April
      21, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020009707/ea120914-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      April 21, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020009822/ea120940-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      April 22, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020009925/ea121002-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      April 23, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020010301/ea121160-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      April 28, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020010962/ea121358-8k_inmune.htm" STYLE="-sec-extract: exhibit">
      May 5, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020011278/ea121501-8k_inmune.htm" STYLE="-sec-extract: exhibit">
      May 7, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020011855/ea121491_inmune.htm" STYLE="-sec-extract: exhibit">
      May 12, 2020</A>, <A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020012422/ea121916-8k_inmune.htm" STYLE="-sec-extract: exhibit">May
      15, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020012725/ea121992-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      May 18, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020014985/ea123053-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      June 15, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020017207/ea124034-8k_inmunebioinc.htm" STYLE="-sec-extract: exhibit">
      July 10, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020017343/ea124121-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      July 13, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020017615/ea124233-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      July 16, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020017924/ea124302-8k_inmunebioinc.htm" STYLE="-sec-extract: exhibit">
      July 20, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020018013/ea124372-8ka_inmune.htm" STYLE="-sec-extract: exhibit">
      July 21, 2020</A>, <A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020018871/ea124640-8k_inmunebioinc.htm" STYLE="-sec-extract: exhibit">July
      28, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020019177/ea124728-8k_inmunebioinc.htm" STYLE="-sec-extract: exhibit">
      July 30, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020019888/ea124913-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      August 3, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020020662/ea125085-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      August 6, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020020897/ea125218-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      August 7, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020022288/ea125554-8k_inmunebioinc.htm" STYLE="-sec-extract: exhibit">
      August 14, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020022769/ea125447-8k_inmune.htm" STYLE="-sec-extract: exhibit">
      August 19, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020025123/ea126391-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      September 3, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020025397/ea126485-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      September 4, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020026558/ea126843-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      September 15, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020027055/ea126963-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      September 17, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020028229/ea127332-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      September 24, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020028780/ea127489-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      September 29 ,2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020029548/ea127685-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      October 1, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020035449/ea129443-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      October 6, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020033364/ea128926-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      October 27, 2020</A>;<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020035449/ea129443-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      November 6, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020035894/ea129550-8k_inmunebioinc.htm" STYLE="-sec-extract: exhibit">
      November 9, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020036253/0001213900-20-036253-index.htm" STYLE="-sec-extract: exhibit">
      November 12, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020045454/ea132482-8k_inmmune.htm" STYLE="-sec-extract: exhibit">
      December 30, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020045464/ea132345-8k_inmune.htm" STYLE="-sec-extract: exhibit">
      December 30, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390021000217/ea132661-8ka1_inmune.htm" STYLE="-sec-extract: exhibit">
      January 4, 2021</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390021003327/ea133643-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      January 21, 2021</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390021003480/ea133728-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      January 21, 2021</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390021004031/ea133876-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      January 25, 2021,</A> <A HREF="http://www.sec.gov/Archives/edgar/data/1711754/000121390021012742/ea136834-8k_inmunebio.htm">March 2, 2021</A>, <A HREF="http://www.sec.gov/Archives/edgar/data/1711754/000121390021013731/ea137109-8k_immunebio.htm">March 5, 2011</A>, <A HREF="http://www.sec.gov/Archives/edgar/data/1711754/000121390021014276/ea137286-8k_inmunebio.htm">March 9, 2011</A> and
      <A HREF="http://www.sec.gov/Archives/edgar/data/1711754/000121390021014649/ea137374-8k_inmunebioinc.htm">March 11, 2021</A>;</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 2.25pt">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">our <A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020023303/ea125901-def14a_inmunebio.htm" STYLE="-sec-extract: exhibit">Definitive Proxy Statement</A> on Schedule 14A filed with the SEC on August 21, 2020; and</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">the description of our common stock, which is contained in the registration statement on <A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000164033419000136/inmune_8a12b.htm" STYLE="-sec-extract: exhibit">Form 8-A</A> filed with the SEC on February 1, 2019 (File No. 001-38793), including any amendments or reports filed for the purpose of updating that description.</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Notwithstanding the foregoing, information
  furnished under Items 2.02 and 7.01 of any Current Report on Form 8-K, including the related exhibits, is not incorporated by reference
  in this Registration Statement.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>
  
  <!-- Field: Page; Sequence: 14 -->
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase"><B><A NAME="a_011"></A>Disclosure
  Of Commission Position On Indemnification </B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase"><B>For
  Securities Act Liabilities</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">NRS 78.7502(1) provides that a corporation
  may indemnify any person who was or is a party or is threatened to be made a party to any threatened, pending or completed action,
  suit or proceeding, whether civil, criminal, administrative or investigative, except an action by or in the right of the corporation,
  by reason of the fact that he is or was a director, officer, employee or agent of the corporation, or is or was serving at the
  request of the corporation as a director, officer, employee or agent of another corporation, partnership, joint venture, trust
  or other enterprise, against expenses, including attorneys' fees, judgments, fines and amounts paid in settlement actually and
  reasonably incurred by him in connection with the action, suit or proceeding if he: (a) is not liable pursuant to NRS 78.138; or
  (b) acted in good faith and in a manner which he reasonably believed to be in or not opposed to the best interests of the corporation,
  and, with respect to any criminal action or proceeding, had no reasonable cause to believe his conduct was unlawful.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-size: 10pt">NRS Section
  78.7502(2) provides that a corporation may indemnify any person who was or is a party or is threatened to be made a party to any
  threatened, pending or completed action or suit by or in the right of the corporation to procure a judgment in its favor by reason
  of the fact that he is or was a director, officer, employee or agent of the corporation, or is or was serving at the request of
  the corporation as a director, officer, employee or agent of another corporation, partnership, joint venture, trust or other enterprise
  against expenses, including amounts paid in settlement and attorneys' fees actually and reasonably incurred by him in connection
  with the defense or settlement of the action or suit if he: (a) is not liable pursuant to NRS 78.138; or (b) acted in good faith
  and in a manner which he reasonably believed to be in or not opposed to the best interests of the corporation. Indemnificatio</FONT>n
  <FONT STYLE="font-size: 10pt">may not be made for any claim, issue or matter as to which such a person has been adjudged by a court
  of competent jurisdiction, after exhaustion of all appeals there from, to be liable to the corporation or for amounts paid in settlement
  to the corporation, unless and only to the extent that the court in which the action or suit was brought or other court of competent
  jurisdiction determines upon application that in view of all the circumstances of the case, the person is fairly and reasonably
  entitled to indemnity for such expenses as the court deems proper.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT><FONT STYLE="font-size: 10pt">Our
  Articles of Incorporation provides that very person who was or is a party to, or is threatened to be made a party to, or is involved
  in any action, suit or proceeding, whether civil, criminal, administrative or investigative, by reason of the fact that he, or
  a person of whom he is the legal representative, is or was a director or officer of the Company, or is or was serving at the request
  of the Company as a director or officer of another corporation, or as its representative in a partnership, joint venture, trust
  or other enterprise, shall be indemnified and held harmless to the fullest extent legally permissible under the laws of the State
  of Nevada from time to time against all expenses, liability and loss (including attorney&rsquo;s fees, judgements, fines and amounts
  paid or to be paid in settlement) reasonably incurred or suffered by him in connection therewith. Such right of indemnification
  shall be a contract right which may be enforced in any matter desired by such person. The expenses of the officers and directors
  incurred in defending a civil or criminal action, suit or proceeding must be paid by the Company as they are incurred and in advance
  of the final disposition of the action, suit or proceeding, upon receipt of an undertaking by or on behalf of the director or officer
  to repay the amount if it is ultimately determined by a court of competent jurisdiction that he is not entitled to be indemnified
  by the Company. Such right of indemnification shall not be exclusive of any other right which such directors, officers or representatives
  may have or hereafter acquire, and, without limiting the generality of such statement, they shall be entitled to their respective
  rights of indemnification under any bylaw, agreement, vote of stockholders, provision of law, or otherwise, as well as their rights
  under this Article.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">NRS Section 78.747 provides that except
  as otherwise provided by specific statute, no director or officer of a corporation is individually liable for a debt or liability
  of the corporation, unless the director or officer acts as the alter ego of the corporation. The court as a matter of law must
  determine the question of whether a director or officer acts as the alter ego of a corporation.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Insofar as indemnification for liabilities
  arising under the Securities Act may be permitted to directors, offices or controlling persons of ours, pursuant to the foregoing
  provisions, or otherwise, we have been advised that, in the opinion of the Securities and Exchange Commission, such indemnification
  is against public policy as expressed in the Securities Act, and is, therefore, unenforceable. In the event that a claim for indemnification
  against such liabilities (other than the payment by us of expenses incurred or paid by a director, officer or controlling person
  of ours in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person
  in connection with the securities being registered hereunder, we will, unless in the opinion of our counsel the matter has been
  settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by us
  is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <!-- Field: Page; Sequence: 15 -->
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      <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
      <!-- Field: /Page -->
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><A NAME="a_012"></A><FONT STYLE="text-transform: uppercase"><B>Additional
  Information Available to You</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">This prospectus is part of a Registration
  Statement on Form S-8 that we filed with the SEC. Certain information in the Registration Statement has been omitted from this
  prospectus in accordance with the rules of the SEC. We file annual, quarterly and special reports, proxy statements and other information
  with the SEC. You can inspect and copy the Registration Statement as well as reports, proxy statements and other information we
  have filed with the SEC at the public reference room maintained by the SEC at 100 F Street N.E. Washington, D.C. 20549, You can
  obtain copies from the public reference room of the SEC at 100 F Street N.E. Washington, D.C. 20549, upon payment of certain fees.
  You can call the SEC at 1-800-732-0330 for further information about the public reference room. We are also required to file electronic
  versions of these documents with the SEC, which may be accessed through the SEC&rsquo;s World Wide Web site at http://www.sec.gov.
  No dealer, salesperson or other person is authorized to give any information or to make any representations other than those contained
  in this prospectus, and, if given or made, such information or representations must not be relied upon as having been authorized
  by us. This prospectus does not constitute an offer to buy any security other than the securities offered by this prospectus, or
  an offer to sell or a solicitation of an offer to buy any securities by any person in any jurisdiction where such offer or solicitation
  is not authorized or is unlawful. Neither delivery of this prospectus nor any sale hereunder shall, under any circumstances, create
  any implication that there has been no change in the affairs of our company since the date hereof.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>PART II </B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>INFORMATION REQUIRED IN THE REGISTRATION
  STATEMENT </B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Item 3. Incorporation of Documents by
  Reference.</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">The Company hereby incorporates by reference
  into this Registration Statement the documents listed below. In addition, all documents subsequently filed pursuant to Sections
  13(a), 13(c), 14 and 15(d) of the Exchange Act, prior to the filing of a post-effective amendment which indicates that all securities
  offered have been sold or which deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference
  into this Registration Statement and to be a part hereof from the date of filing of such documents.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">our Annual Report on Form<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390021013456/f10k2020_inmunebioinc.htm" STYLE="-sec-extract: exhibit"> 10-K</A> for the fiscal
      year ended December 31, 2020, filed with the SEC on March 4, 2021;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">our Annual Report on Form<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020005916/f10k2019_inmunebioinc.htm" STYLE="-sec-extract: exhibit"> 10-K</A> for the fiscal
      year ended December 31, 2019, filed with the SEC on March 11, 2020;</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">our Quarterly Report on Form<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020012056/f10q0320_inmunebio.htm" STYLE="-sec-extract: exhibit"> 10-Q</A> for the period ended March 31, 2020, filed with the SEC May 14, 2020; </FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">our Quarterly Report on Form<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020020373/f10q0620_inmunebio.htm" STYLE="-sec-extract: exhibit"> 10-Q</A> for the period ended June 30, 2020, filed with the SEC August 5, 2020;</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">our Quarterly Report on Form<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020035280/f10q0920_inmunebioinc.htm" STYLE="-sec-extract: exhibit"> 10-Q</A> for the period ended September 30, 2020, filed with the SEC on November 5, 2020; </FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 2.25pt">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">our Current Reports on Form 8-K or Form 8-K/A
      filed with the SEC on<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020006109/ea119517-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      March 12, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020008917/ea120559-8k_inmunebioinc.htm" STYLE="-sec-extract: exhibit">
      April 9, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020009372/ea120711-8k_inmunebioinc.htm" STYLE="-sec-extract: exhibit">
      April 17, 2020</A>, <A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020009642/ea120866-8k_inmune.htm" STYLE="-sec-extract: exhibit">April
      21, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020009707/ea120914-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      April 21, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020009822/ea120940-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      April 22, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020009925/ea121002-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      April 23, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020010301/ea121160-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      April 28, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020010962/ea121358-8k_inmune.htm" STYLE="-sec-extract: exhibit">
      May 5, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020011278/ea121501-8k_inmune.htm" STYLE="-sec-extract: exhibit">
      May 7, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020011855/ea121491_inmune.htm" STYLE="-sec-extract: exhibit">
      May 12, 2020</A>, <A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020012422/ea121916-8k_inmune.htm" STYLE="-sec-extract: exhibit">May
      15, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020012725/ea121992-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      May 18, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020014985/ea123053-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      June 15, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020017207/ea124034-8k_inmunebioinc.htm" STYLE="-sec-extract: exhibit">
      July 10, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020017343/ea124121-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      July 13, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020017615/ea124233-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      July 16, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020017924/ea124302-8k_inmunebioinc.htm" STYLE="-sec-extract: exhibit">
      July 20, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020018013/ea124372-8ka_inmune.htm" STYLE="-sec-extract: exhibit">
      July 21, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020018871/ea124640-8k_inmunebioinc.htm" STYLE="-sec-extract: exhibit">
      July 28, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020019177/ea124728-8k_inmunebioinc.htm" STYLE="-sec-extract: exhibit">
      July 30, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020019888/ea124913-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      August 3, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020020662/ea125085-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      August 6, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020020897/ea125218-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      August 7, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020022288/ea125554-8k_inmunebioinc.htm" STYLE="-sec-extract: exhibit">
      August 14, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020022769/ea125447-8k_inmune.htm" STYLE="-sec-extract: exhibit">
      August 19, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020025123/ea126391-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      September 3, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020025397/ea126485-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      September 4, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020026558/ea126843-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      September 15, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020027055/ea126963-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      September 17, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020028229/ea127332-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      September 24, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020028780/ea127489-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      September 29 ,2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020029548/ea127685-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      October 1, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020030205/ea127851-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      October 6, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020035449/ea129443-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      October 27, 2020</A>;<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020035449/ea129443-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      November 6, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020035894/ea129550-8k_inmunebioinc.htm" STYLE="-sec-extract: exhibit">
      November 9, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020036253/ea129655-8k_inmunebioinc.htm" STYLE="-sec-extract: exhibit">
      November 12, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020045454/ea132482-8k_inmmune.htm" STYLE="-sec-extract: exhibit">
      December 30, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020045464/ea132345-8k_inmune.htm" STYLE="-sec-extract: exhibit">
      December 30, 2020</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390021000217/ea132661-8ka1_inmune.htm" STYLE="-sec-extract: exhibit">
      January 4, 2021</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390021003327/ea133643-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      January 21, 2021</A>,<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390021003480/ea133728-8k_inmunebio.htm" STYLE="-sec-extract: exhibit">
      January 21, 2021</A>,
      <A HREF="http://www.sec.gov/Archives/edgar/data/1711754/000121390021004031/ea133876-8k_inmunebio.htm">January 25, 2021</A>, <A HREF="http://www.sec.gov/Archives/edgar/data/1711754/000121390021012742/ea136834-8k_inmunebio.htm">March 2, 2021</A>, <A HREF="http://www.sec.gov/Archives/edgar/data/1711754/000121390021013731/ea137109-8k_immunebio.htm">March 5, 2021</A>, <A HREF="http://www.sec.gov/Archives/edgar/data/1711754/000121390021014276/ea137286-8k_inmunebio.htm">March 9, 2021</A> and <A HREF="http://www.sec.gov/Archives/edgar/data/1711754/000121390021014649/ea137374-8k_inmunebioinc.htm">March 11, 2021</A>;</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 2.25pt">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">our<A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000121390020023303/ea125901-def14a_inmunebio.htm" STYLE="-sec-extract: exhibit"> Definitive Proxy Statement</A> on Schedule 14A filed with the SEC on August 21, 2020; and</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">the description of our common stock, which is contained in the registration statement on Form <A HREF="https://www.sec.gov/Archives/edgar/data/1711754/000164033419000136/inmune_8a12b.htm" STYLE="-sec-extract: exhibit">8-A</A> filed with the SEC on February 1, 2019 (File No. 001-38793), including any amendments or reports filed for the purpose of updating that description.</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Notwithstanding the foregoing, information
  furnished under Items 2.02 and 7.01 of any Current Report on Form 8-K, including the related exhibits, is not incorporated by reference
  in this Registration Statement.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Item 4. Description of Securities.</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Not applicable.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Item 5. Interests of Named Experts and
  Counsel.</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">None.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;&nbsp;</P>
  
  <!-- Field: Page; Sequence: 16 -->
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Item 6. Indemnification of Directors
  and Officers.</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">NRS 78.7502(1) provides that a corporation
  may indemnify any person who was or is a party or is threatened to be made a party to any threatened, pending or completed action,
  suit or proceeding, whether civil, criminal, administrative or investigative, except an action by or in the right of the corporation,
  by reason of the fact that he is or was a director, officer, employee or agent of the corporation, or is or was serving at the
  request of the corporation as a director, officer, employee or agent of another corporation, partnership, joint venture, trust
  or other enterprise, against expenses, including attorneys' fees, judgments, fines and amounts paid in settlement actually and
  reasonably incurred by him in connection with the action, suit or proceeding if he: (a) is not liable pursuant to NRS 78.138; or
  (b) acted in good faith and in a manner which he reasonably believed to be in or not opposed to the best interests of the corporation,
  and, with respect to any criminal action or proceeding, had no reasonable cause to believe his conduct was unlawful.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-size: 10pt">NRS Section
  78.7502(2) provides that a corporation may indemnify any person who was or is a party or is threatened to be made a party to any
  threatened, pending or completed action or suit by or in the right of the corporation to procure a judgment in its favor by reason
  of the fact that he is or was a director, officer, employee or agent of the corporation, or is or was serving at the request of
  the corporation as a director, officer, employee or agent of another corporation, partnership, joint venture, trust or other enterprise
  against expenses, including amounts paid in settlement and attorneys' fees actually and reasonably incurred by him in connection
  with the defense or settlement of the action or suit if he: (a) is not liable pursuant to NRS 78.138; or (b) acted in good faith
  and in a manner which he reasonably believed to be in or not opposed to the best interests of the corporation. Indemnificatio</FONT>n
  <FONT STYLE="font-size: 10pt">may not be made for any claim, issue or matter as to which such a person has been adjudged by a court
  of competent jurisdiction, after exhaustion of all appeals there from, to be liable to the corporation or for amounts paid in settlement
  to the corporation, unless and only to the extent that the court in which the action or suit was brought or other court of competent
  jurisdiction determines upon application that in view of all the circumstances of the case, the person is fairly and reasonably
  entitled to indemnity for such expenses as the court deems proper.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT><FONT STYLE="font-size: 10pt">Our
  Articles of Incorporation provides that very person who was or is a party to, or is threatened to be made a party to, or is involved
  in any action, suit or proceeding, whether civil, criminal, administrative or investigative, by reason of the fact that he, or
  a person of whom he is the legal representative, is or was a director or officer of the Company, or is or was serving at the request
  of the Company as a director or officer of another corporation, or as its representative in a partnership, joint venture, trust
  or other enterprise, shall be indemnified and held harmless to the fullest extent legally permissible under the laws of the State
  of Nevada from time to time against all expenses, liability and loss (including attorney&rsquo;s fees, judgements, fines and amounts
  paid or to be paid in settlement) reasonably incurred or suffered by him in connection therewith. Such right of indemnification
  shall be a contract right which may be enforced in any matter desired by such person. The expenses of the officers and directors
  incurred in defending a civil or criminal action, suit or proceeding must be paid by the Company as they are incurred and in advance
  of the final disposition of the action, suit or proceeding, upon receipt of an undertaking by or on behalf of the director or officer
  to repay the amount if it is ultimately determined by a court of competent jurisdiction that he is not entitled to be indemnified
  by the Company. Such right of indemnification shall not be exclusive of any other right which such directors, officers or representatives
  may have or hereafter acquire, and, without limiting the generality of such statement, they shall be entitled to their respective
  rights of indemnification under any bylaw, agreement, vote of stockholders, provision of law, or otherwise, as well as their rights
  under this Article.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">NRS Section 78.747 provides that except
  as otherwise provided by specific statute, no director or officer of a corporation is individually liable for a debt or liability
  of the corporation, unless the director or officer acts as the alter ego of the corporation. The court as a matter of law must
  determine the question of whether a director or officer acts as the alter ego of a corporation.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Insofar as indemnification for liabilities
  arising under the Securities Act may be permitted to directors, offices or controlling persons of ours, pursuant to the foregoing
  provisions, or otherwise, we have been advised that, in the opinion of the Securities and Exchange Commission, such indemnification
  is against public policy as expressed in the Securities Act, and is, therefore, unenforceable. In the event that a claim for indemnification
  against such liabilities (other than the payment by us of expenses incurred or paid by a director, officer or controlling person
  of ours in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person
  in connection with the securities being registered hereunder, we will, unless in the opinion of our counsel the matter has been
  settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by us
  is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>&nbsp;&nbsp;</B></P>
  
  <!-- Field: Page; Sequence: 17 -->
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      <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Item 7. Exemption from Registration
  Claimed.</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Not applicable.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Item 8. Exhibits.</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>&nbsp;</B></P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 9%; border-bottom: black 1pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Exhibit Number</B></FONT></TD>
      <TD STYLE="width: 1%">&nbsp;</TD>
      <TD STYLE="border-bottom: black 1pt solid; width: 90%">
          <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>
          <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Description</B></P></TD></TR>
  <TR STYLE="vertical-align: top; background-color: #CCEEFF">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.1</FONT></TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: justify"><A HREF="ea137528ex5-1_inmunebioinc.htm" STYLE="-sec-extract: exhibit"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; color: blue">Opinion of Sichenzia Ross Ference LLP*</FONT></A></TD></TR>
  <TR STYLE="vertical-align: top; background-color: white">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">23.1</FONT></TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: justify"><A HREF="ea137528ex23-1_inmunebioinc.htm" STYLE="-sec-extract: exhibit"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; color: blue">Consent of Marcum LLP*</FONT></A></TD></TR>
  <TR STYLE="vertical-align: top; background-color: #CCEEFF">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">23.2</FONT></TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: justify"><A HREF="ea137528ex5-1_inmunebioinc.htm" STYLE="-sec-extract: exhibit"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; color: blue">Consent of Sichenzia Ross Ference LLP (included in Exhibit 5.1)*</FONT></A></TD></TR>
  <TR STYLE="vertical-align: top; background-color: white">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">24.1</FONT></TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: justify"><A HREF="#a_001"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; color: blue">Power of Attorney (included on the signature page)</FONT></A></TD></TR>
  <TR STYLE="vertical-align: top; background-color: #CCEEFF">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">99.1 </FONT></TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: justify"><A HREF="ea137528ex99-1_inmunebioinc.htm"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">INmune Bio Inc. 2017 Stock Incentive Plan</FONT></A></TD></TR>
  <TR STYLE="vertical-align: top; background-color: white">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">99.2</FONT></TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: justify"><A HREF="ea137528ex99-2_inmunebioinc.htm"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">INmune Bio Inc. 2019 Stock Incentive Plan</FONT></A></TD></TR>
  </TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 4%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;*</FONT></TD>
      <TD STYLE="width: 96%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Filed herewith</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Item 9. Undertakings.</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 0px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(a)</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">The Company hereby undertakes:</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; background-color: white">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px; text-align: justify">&nbsp;</TD>
      <TD STYLE="width: 24px; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; background-color: white">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 48px; text-align: justify">&nbsp;</TD>
      <TD STYLE="width: 24px; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(i)</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">To include any prospectus required by Section&nbsp;10(a)(3) of the Securities Act.</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; background-color: white">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 48px; text-align: justify">&nbsp;</TD>
      <TD STYLE="width: 24px; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(ii)</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">To reflect in the prospectus any facts or events arising after the effective date of the Registration Statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the Registration Statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities offered&nbsp;&nbsp;would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus filed with the Securities and Exchange Commission pursuant to Rule 424(b) if, in the aggregate, the changes in volume and price represent no more than 20 percent change in the maximum aggregate offering price set forth in the &ldquo;Calculation of Registration Fee&rdquo; table in the effective Registration Statement.</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; background-color: white">&nbsp;&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; background-color: white"></P>
  
  <!-- Field: Page; Sequence: 18 -->
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      <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; background-color: white">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 48px; text-align: justify">&nbsp;</TD>
      <TD STYLE="width: 24px; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(iii)</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">To include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement or any material change to such information in the Registration Statement; provided, however, that (A)&nbsp;paragraphs (a)(1)(i) and (a)(1)(ii) of this section do not apply if the Registration Statement is on Form S&ndash;8 (&sect;239.16b of Regulation S-K), and the information required to be included in a post-effective amendment by those paragraphs is contained in reports filed with or furnished to the Securities and Exchange Commission by the Company pursuant to section 13 or section 15(d) of the Exchange Act (15 U.S.C. 78m or 78o(d)) that are incorporated by reference in the Registration Statement; and (B)&nbsp;paragraphs (a)(1)(i), (a)(1)(ii) and (a)(1)(iii) do not apply if the Registration Statement is on Form S-3 or Form F-3, and the information required to be included in a post-effective amendment by those paragraphs is contained in reports filed with or furnished to the Securities and Exchange Commission by the Company pursuant to Section&nbsp;13 or Section&nbsp;15(d) of the Exchange Act that are incorporated by reference in the Registration Statement, or is contained in a form of prospectus filed pursuant to Rule 424(b) that is part of the Registration Statement; provided further, however, that paragraphs (a)(1)(i) and (a)(1)(ii) do not apply if the Registration Statement is for an offering of asset-backed securities on Form S-1 or Form S-3, and the information required to be included in a post-effective amendment is provided pursuant to Item&nbsp;1100(c) of Regulation AB.</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; background-color: white">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px; text-align: justify">&nbsp;</TD>
      <TD STYLE="width: 24px; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(2)</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; background-color: white">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px; text-align: justify">&nbsp;</TD>
      <TD STYLE="width: 24px; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(3)</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; background-color: white">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 24px; text-align: justify">&nbsp;</TD>
      <TD STYLE="width: 24px; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(4)</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">That, for the purpose of determining liability under the Securities Act of 1933 to any purchaser:</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; background-color: white">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">(A)&nbsp;Each prospectus
  filed by a Registrant pursuant to Rule&nbsp;424(b)(3) shall be deemed to be part of the registration statement as of the date the
  filed prospectus was deemed part of and included in the registration statement; and</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; background-color: white">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">(B)&nbsp;Each prospectus
  required to be filed pursuant to Rule&nbsp;424(b)(2), (b)(5) or (b)(7) as part of a registration statement in reliance on Rule&nbsp;430B
  relating to an offering made pursuant to Rule&nbsp;415(a)(1)(i),&nbsp;&nbsp;(vii)&nbsp;or (x)&nbsp;for the purpose of providing
  the information required by Section 10(a) of the Securities Act of 1933 shall be deemed to be part of and included in the registration
  statement as of the earlier of the date such form of prospectus is first used after effectiveness or the date of the first contract
  of sale of securities in the offering described in the prospectus. As provided in Rule&nbsp;430B, for liability purposes of the
  issuer and any person that is at that date an underwriter, such date shall be deemed to be a new effective date of the registration
  statement relating to the securities in the registration statement to which the prospectus relates, and the offering of such securities
  at that time shall be deemed to be the initial bona fide offering thereof. Provided, however, that no statement made in a registration
  statement or prospectus that is part of the registration statement or made in a document incorporated or deemed incorporated by
  reference into the registration statement or prospectus that is part of the registration statement will, as to a purchaser with
  a time of contract of sale prior to such effective date, supersede or modify any statement that was made in the registration statement
  or prospectus that was part of the registration statement or made in any such document immediately prior to such effective date.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; background-color: white">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 0px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(b)</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">The Company hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the Company&rsquo;s annual report pursuant to Section&nbsp;13(a) or Section&nbsp;15(d) of the Exchange Act that is incorporated by reference in this Registration Statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; background-color: white">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 0px">&nbsp;</TD>
      <TD STYLE="width: 24px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(c)</FONT></TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the Company pursuant to the foregoing provisions, or otherwise, the Company has been advised that in the opinion of the Securities and Exchange Commission such indemnification is against public policy as expressed in the Securities Act, and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the Company of expenses incurred or paid by a director, officer or controlling person of the Company in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered, the Company will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B></B></P>
  
  <!-- Field: Page; Sequence: 19 -->
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      <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
      <!-- Field: /Page -->
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B></B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><A NAME="a_001"></A><B>SIGNATURES </B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in"><FONT STYLE="background-color: white">Pursuant
  to the requirements of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it
  meets all of the requirements for filing on Form S-8 and has duly caused this registration statement to be signed on its behalf
  by the undersigned, thereunto duly authorized, in the City of La Jolla, State of California, on March 22, 2021</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 60%">&nbsp;</TD>
      <TD STYLE="width: 40%">
          <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>INmune Bio Inc. </B></P>
          <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>&nbsp;</B></P></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD STYLE="border-bottom: Black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Raymond J. Tesi</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Raymond J. Tesi, M. D. </FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Chief Executive Officer</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Principal Executive Officer)</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD STYLE="border-bottom: black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ David J. Moss</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">David J. Moss</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Chief Financial Officer</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Principal Financial and Accounting Officer)</FONT></TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD COLSPAN="2"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">INMUNE BIO INC.</FONT></TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 48px">&nbsp;</TD>
      <TD STYLE="width: 48px">&nbsp;</TD>
      <TD STYLE="width: 336px">&nbsp;</TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">By:</FONT></TD>
      <TD STYLE="border-bottom: Black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Raymond J. Tesi</FONT></TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Raymond J. Tesi</FONT></TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Its:</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Chief Executive Officer</FONT></TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Principal Executive Officer)</FONT></TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">By:</FONT></TD>
      <TD STYLE="border-bottom: Black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ David J. Moss</FONT></TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">David J. Moss</FONT></TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Its:</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Chief Financial Officer</FONT></TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Principal Financial and Accounting Officer)&nbsp;&nbsp;</FONT></TD>
      <TD>&nbsp;</TD></TR>
  </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 27.5pt">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in"></P>
  
  <!-- Field: Page; Sequence: 20 -->
      <DIV STYLE="margin-top: 6pt; margin-bottom: 6pt; border-bottom: Black 1.5pt solid"><P STYLE="text-align: center; margin-top: 0pt; margin-bottom: 0pt"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->20<!-- Field: /Sequence --></P></DIV>
      <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
      <!-- Field: /Page -->
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">Each person whose signature appears below
  constitutes and appoints Raymond J. Tesi and David J. Moss, and each of them severally, as his true and lawful attorney in fact
  and agent, with full powers of substitution and re-substitution, for him and in his name, place and stead, in any and all capacities,
  to sign any or all amendments (including post effective amendments) to the Registration Statement, and to sign any registration
  statement for the same offering covered by this Registration Statement that is to be effective upon filing pursuant to Rule 462(b)
  under the Securities Act of 1933, as amended, and all post effective amendments thereto, and to file the same, with all exhibits
  thereto, and all documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorney-in-fact
  and agent, each acting alone, full power and authority to do and perform each and every act and thing requisite and necessary to
  be done in and about the premises, as fully to all intents and purposes as he or she might or could do in person, hereby ratifying
  and confirming all that said attorney-in-fact and agent, each acting alone, or his or her substitute or substitutes, may lawfully
  do or cause to be done by virtue hereof.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">Pursuant to the requirements of the Securities
  Act of 1933, this registration statement has been signed below by the following persons in the capacities and on the dates indicated.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 40%; border-bottom: black 1.5pt solid; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Raymond J. Tesi</FONT></TD>
      <TD STYLE="width: 35%; text-align: justify">&nbsp;</TD>
      <TD STYLE="width: 25%; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">March 22, 2021</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Raymond J. Tesi, M.D. </FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>
          <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Chief Executive Officer and</P>
          <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Director (principal executive officer)</P></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: black 1.5pt solid; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ David J. Moss</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">March 22, 2021</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">David J. Moss</FONT></TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>
          <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Chief Financial Officer</P>
          <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">(principal financial and accounting officer)</P></TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: black 1.5pt solid; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Timothy Schroeder</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">March 22, 2021</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Timothy Schroeder</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: black 1.5pt solid; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ David Szymkowski</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">March 22, 2021</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">David Szymkowski</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: black 1.5pt solid; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ J. Kelly Ganjei</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">March 22, 2021</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">J. Kelly Ganjei </FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: black 1.5pt solid; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Scott Juda, JD</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">March 22, 2021</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Scott Juda, JD</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: black 1.5pt solid; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Edgardo Baracchini</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">March 22, 2021</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Edgardo Baracchini</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: black 1.5pt solid; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Marcia Allen</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">March 22, 2021</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Marcia Allen</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  </TABLE>
  
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metadata_documents: [{"type": "S-8", "sequence": "1", "filename": "ea137528-s8_inmunebioinc.htm", "description": "REGISTRATION STATEMENT", "secsgml_size_bytes": 190473}]
metadata_filer: {"company-data": {"conformed-name": "Inmune Bio, Inc.", "cik": "0001711754", "assigned-sic": "2836", "irs-number": "475205835", "state-of-incorporation": "NV", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-254577", "film-number": "21761841"}, "business-address": {"street1": "1200 PROSPECT STREET", "street2": "SUITE 525", "city": "LA JOLLA", "state": "CA", "zip": "92037", "phone": "8589643720"}, "mail-address": {"street1": "1200 PROSPECT STREET", "street2": "SUITE 525", "city": "LA JOLLA", "state": "CA", "zip": "92037"}}
text: UNITED STATES
  SECURITIES AND EXCHANGE COMMISSION
  Washington, D.C. 20549
  FORM S-8
  REGISTRATION STATEMENT UNDER THE SECURITIES
  ACT OF 1933
  INMUNE BIO INC.
  (Exact name of registrant as specified in
  its charter)
  Nevada
  (State or other jurisdiction of
  incorporation or organization)
  47-5205835
  (I.R.S. Employer
  identification No.)
  1200 Prospect Street, Suite 525, La Jolla,
  CA 92037
  (Address of principal executive
  offices) (Zip Code)
  INmune Bio Inc. 2017 Stock Incentive
  Plan
  INmune Bio Inc. 2019 Stock Incentive
  Plan
  (Full title of the plans)
  David Moss
  Chief Financial Officer
  INmune Bio, Inc.
  1200 Prospect Street, Suite 525,
  La Jolla, CA 92037
  (Name and address of agent for service)
  585-359-5900
  (Telephone number, including area code,
  of agent for service)
  Copies to:
  Marc Ross, Esq.
  Thomas A. Rose, Esq.
  David B. Manno, Esq.
  Sichenzia Ross Ference LLP
  1185 Avenue of the Americas, 31
  st
  Floor
  New York, New York 10036
  Phone: 212- 930-9700
  Fax: 212-930-9725
  Indicate by check mark whether the registrant
  is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth
  company. See the definitions of "large accelerated filer," "accelerated filer," "smaller reporting
  company," and "emerging growth company" in Rule 12b-2 of the Exchange Act.
  Large accelerated
  filer
  ☐
  Accelerated
  filer  ☐
  Non-accelerated
  filer  ☒
  Smaller reporting
      company
  ☒
  Emerging
  growth company  ☒
  If
  an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for
  complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act.
  ¨
  CALCULATION OF REGISTRATION FEE
  Title of each class of securities
  to be registered
  Amount to be Registered
  (1)
  Proposed Maximum Offering Price Per Security
  Proposed Maximum Aggregate Offering Price
  Amount of Registration Fee
  Common Stock, $0.001 par value
  (2)
  1,700,000
  $
  18.81
  $
  31,977,000
  (3)
  $
  3,488.69
  Common Stock, $0.001 par value
  (4)
  2,000,000
  $
  18.81
  $
  37,620,000
  (3)
  $
  4,104.34
  Total
  3,700,000
  $
  69,597,000
  (3)
  $
  7,593.03
  (1)
  Pursuant to Rule 416 promulgated under the Securities Act of 1933, as amended, there are also registered hereunder such indeterminate number of additional shares as may be issued to prevent dilution resulting from stock splits, stock dividends or similar transactions.
  (2)
  Represents shares issued or issuable pursuant to the INmune Bio, Inc., 2017 Equity Incentive Plan.
  (3)
  Estimated solely for purposes of calculating the registration fee in accordance with Rule 457(c) under the Securities Act of 1933, as amended, using the average of the high and low price as reported on the NASDAQ Capital Market on February 22, 2021.
  (4)
  Represents shares issued or issuable pursuant to the INmune Bio, Inc., 2019 Equity Incentive Plan.
  PART I
  INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS
  This Registration Statement relates to
  two separate prospectuses.
  Section 10(a) Prospectus
  : Items
  1 and 2, from this page, and the documents incorporated by reference pursuant to Part II, Item 3 of this prospectus, constitute
  a prospectus that meets the requirements of Section 10(a) of the Securities Act of 1933, as amended (the "Securities Act").
  Reoffer Prospectus
  : The material
  that follows Item 2, up to but not including Part II of this Registration Statement, of which the reoffer prospectus is a part,
  constitutes a "reoffer prospectus," prepared in accordance with the requirements of Part I of Form S-3 under the Securities
  Act. Pursuant to Instruction C of Form S-8, the reoffer prospectus may be used for reoffers or resales of shares of common stock
  which are deemed to be "control securities" or "restricted securities" under the Securities Act that have
  been acquired by the selling stockholders named in the reoffer prospectus.
  Item 1.            Plan
  Information.
  INmune Bio Inc. will provide each participant
  (the "Recipient") with documents that contain information related to the INmune Bio Inc. 2017 Equity Incentive Plan
  (the "2017 Plan") and the INmune Bio Inc. 2019 Equity Incentive Plan (the "2019 Plan"), and other information
  including, but not limited to, the disclosure required by Item 1 of Form S-8, which information is not filed as a part of this
  Registration Statement on Form S-8. The foregoing information and the documents incorporated by reference in response to Item 3
  of Part II of this Registration Statement taken together constitute a prospectus that meets the requirements of Section 10(a) of
  the Securities Act. A Section 10(a) prospectus will be given to each Recipient who receives shares of common stock covered by this
  Registration Statement, in accordance with Rule 428(b)(1) under the Securities Act.
  Item 2.            Registrant
  Information and Employee Plan Annual Information.
  We will provide to each Recipient a written
  statement advising it of the availability of documents incorporated by reference in Item 3 of Part II of this Registration Statement
  and of documents required to be delivered pursuant to Rule 428(b) under the Securities Act without charge and upon written or oral
  notice by contacting:
  INmune Bio, Inc.
  1200 Prospect Street,
  Suite 525,
  La Jolla, CA 92037
  Attention: Corporate
  Secretary
  Telephone: 585-359-5900
  Information required by Part I to be
  contained in Section 10(a) prospectus is omitted from the Registration Statement in accordance with Rule 428 under the Securities
  Act of 1933, and Note to Part I of Form S-8.
  3
  REOFFER PROSPECTUS
  INmune Bio Inc.
  3,700,000 Shares of Common Stock
  Issued or issuable under certain awards
  granted under the Plans
  This reoffer prospectus relates to the
  sale of 3,700,000 shares of our common stock that may be offered and resold from time to time by the selling stockholders identified
  in this prospectus for their own account. Such shares have been or may be acquired in connection with awards granted under the
  INmune Bio Inc. 2017 Equity Incentive Plan (the "2017 Plan") and the INmune Bio Inc. 2019 Equity Inventive Plan (the
  "2019 Plan," and collectively with the 2017 Plan, the "Plans"). It is anticipated that the selling stockholders
  will offer shares for sale at prevailing prices on the NASDAQ Capital Market on the date of sale. We will receive no part of the
  proceeds from sales made under this reoffer prospectus. The selling stockholders will bear all sales commissions and similar expenses.
  Any other expenses incurred by us in connection with the registration and offering and not borne by the selling stockholders will
  be borne by us.
  This reoffer prospectus has been prepared
  for the purposes of registering the shares under the Securities Act of 1933, as amended (the "Securities Act") to allow
  for future sales by selling stockholders on a continuous or delayed basis to the public without restriction.
  The selling stockholders and any brokers
  executing selling orders on their behalf may be deemed to be "underwriters" within the meaning of the Securities Act,
  in which event commissions received by such brokers may be deemed to be underwriting commissions under the Securities Act.
  Our common stock is quoted on the NASDAQ
  Capital Market under the symbol "INMB." The last reported sale price of our common stock on the NASDAQ Capital Market
  on February 22, 2021, was $18.04 per share.
  We are an "emerging growth company"
  as that term is used in the Jumpstart Our Business Startups Act of 2012, or the JOBS Act, and, as such, have elected to comply
  with certain reduced public company reporting requirements for this prospectus supplement, the accompanying prospectus and our
  filings with the Securities and Exchange Commission.
  Investing in our common stock involves a high degree of risk.
  See "Risk Factors" beginning on page [S-5] of this prospectus supplement and page 5 of the accompanying prospectus.
  Neither the Securities and Exchange Commission nor any state
  securities commission has approved or disapproved of these securities or determined if this prospectus supplement is truthful or
  complete. Any representation to the contrary is a criminal offense.
  4
  The date of this prospectus is March 22, 2021.
  TABLE OF CONTENTS
  Page
  Prospectus Summary
  6
  Risk Factors
  8
  Cautionary Note Regarding Forward Looking Statements
  9
  Use of Proceeds
  9
  Selling Stockholders
  9
  Plan of Distribution
  11
  Legal Matters
  14
  Experts
  14
  Incorporation of Certain Documents by Reference
  14
  Disclosure of Commission Position on Indemnification For Securities Act Liabilities
  15
  Additional Information Available to You
  16
  NO PERSON HAS BEEN AUTHORIZED TO GIVE
  ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE CONTAINED IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFERING
  MADE HEREBY, AND, IF GIVEN OR MADE, SUCH INFORMATION OR REPRESENTATION MUST NOT BE RELIED UPON AS HAVING BEEN AUTHORIZED BY THE
  COMPANY OR ANY OTHER PERSON. NEITHER THE DELIVERY OF THIS PROSPECTUS NOR ANY SALE MADE HEREUNDER SHALL UNDER ANY CIRCUMSTANCES
  CREATE ANY IMPLICATION THAT THERE HAS BEEN NO CHANGE IN THE AFFAIRS OF THE COMPANY SINCE THE DATE HEREOF. THIS PROSPECTUS DOES
  NOT CONSTITUTE AN OFFER TO SELL OR A SOLICITATION OF AN OFFER TO BUY ANY SECURITIES OFFERED HEREBY BY ANYONE IN ANY JURISDICTION
  IN WHICH SUCH OFFER OR SOLICITATION IS NOT AUTHORIZED OR IN WHICH THE PERSON MAKING SUCH OFFER OR SOLICITATION IS NOT QUALIFIED
  TO DO SO OR TO ANY PERSON TO WHOM IT IS UNLAWFUL TO MAKE SUCH OFFER OR SOLICITATION.
  5
  PROSPECTUS SUMMARY
  This summary highlights information contained
  elsewhere in this prospectus. You should read the entire prospectus carefully, including the section entitled "Risk Factors"
  before deciding to invest in our common stock. In this prospectus, the "Company," "we," "us"
  and "our" refer to INmune Bio Inc. and its subsidiaries.
  Company Overview
  We are a clinical-stage immunotherapy company
  focused on developing drugs that may reprogram the patient's innate immune system to treat disease. We believe this may be
  done by targeting cells of the innate immune system that cause acute and chronic inflammation and are involved in the immune dysfunction
  associated with chronic diseases such as cancer, neurodegenerative, metabolic and infectious diseases. The Company has two therapeutic
  platforms – dominant-negative TNF platform ("DN-TNF") and the Natural Killer ("NK") platform. The
  DN-TNF platform neutralizes soluble TNF ("sTNF") without affecting trans-membrane TNF ("tmTNF") or the
  receptors TNFR1 and TNFR2. This unique biologic mechanism differentiates the DN-TNF drugs from currently approved non-selective
  TNF inhibitors that inhibit the function of both sTNF and tmTNF. Protecting the function of tmTNF while neutralizing the function
  of sTNF is a potent anti-inflammatory drug that does not cause immunosuppression or demyelination. Currently approved non-selective
  TNF inhibitors are approved to treat autoimmune disease, however they are contraindicated in patients with infection, cancer and
  neurologic diseases because they increase the risk of infection, cancer and demyelinating neurologic diseases, respectively, because
  of off-target effects on inhibiting tmTNF. The NK platform targets the dysfunctional natural killer cells ("NK cells")
  in patients with cancer. NK cells are part of the normal immunologic response to cancer with important roles in immunosurveillance
  to prevent cancer and in preventing relapse by clearing residual disease. Residual disease is the cancer left behind, often undetected,
  that can grow and cause relapse. The NK cells of cancer patients have the ability to kill cancer cells but are not effective because
  cancer cells mutate to evade NK cell immune surveillance. INKmune provides the missing signals needed to prime NK cells to overcome
  the immune evasion mutation to allow NK cells to kill the cancer cell. We believe INKmune is best used to eliminate residual disease
  after the patient has completed other cancer therapies. Both the DN-TNF platform and the INKmune platform can be used to treat
  multiple diseases. The DN-TNF platform will be used as an immunotherapy for the treatment of cancer, neurodegenerative, metabolic
  and infectious diseases. INKmune is being developed to treat NK sensitive hematologic malignancies and solid tumors.
  We believe our DN-TNF platform can be used
  to reverse resistance in immunotherapy, to target glial activation to prevent progression of Alzheimer's disease ("AD"),
  to target neuroinflammation in treatment resistant depression ("TRD"), to target intestinal leak and inflammation to
  treat non-alcoholic steatohepatitis ("NASH") and to treat complications of the cytokine storm associated with COVID-19
  infection. The drug is named differently for each indication; INB03, XPro1595, LIVNate and Quellor, respectively, but it is the
  same drug product. In each case, we believe neutralizing sTNF is a cornerstone to the treatment of each of these diseases. As an
  immunotherapy for cancer, we are using INB03 to neutralize sTNF produced by HER2+ trastuzumab resistant breast cancers to reverse
  resistance to therapy. sTNF causes an up-regulation of MUC4 expression that causes steric hindrance of trastuzumab binding to the
  HER2/Neu receptor on HER2+ breast cancer cells. Without binding, trastuzumab is not effective. In addition, INB03 changes the immunobiology
  of the tumor microenvironment by decreasing the number of immunosuppressive myeloid cells, both myeloid derived suppressor cells
  and tumor active macrophages, and increasing the number of cytotoxic lymphocytes in the TME. The Company has completed an open
  label dose escalation trial in cancer patients with metastatic solid tumors that have failed multiple lines of therapy. The trial
  informs the design of the Phase II trial by demonstrating that INB03 was safe and well tolerated, defined the dose of INB03 to
  carry into Phase II trials, and demonstrated a pharmacodynamic end-point. A Phase II trial is planned in women with advanced HER2+
  breast cancer with metastasis.
  6
  Likewise, we believe the DN-TNF platform
  can be used to treat selected neurodegenerative diseases. XPro1595 is being used to treat patients with Alzheimer's disease
  in a Phase I trial partially funded by a Part-the-Clouds Award from the Alzheimer's Association. XPro1595 targets activated
  microglia and astrocytes of the brain that produce sTNF that promotes nerve cell loss and synaptic dysfunction, key elements in
  the development of dementia. In animal models, elimination of sTNF prevents nerve cell dysfunction and reverses synaptic pruning.
  The Phase I trial in patients with biomarkers of inflammation with AD is enrolling patients. The open label, dose escalation trial
  is designed to demonstrate that XPro1595 decreases neuroinflammation in patients with AD. This end-points of the trial are measures
  of neuroinflammation and neurodegeneration in blood and cerebral spinal fluid, measures of neuroinflammation by MRI by measuring
  white matter free water and breath by measuring volatile organic compounds in exhaled breath and by monitoring neuropsychiatric
  symptoms known to be associated with neuroinflammation including depression, apathy, aggression, hallucinations and sleep disorders.
  In addition, we believe the DN-TNF platform
  can be used to treat selected metabolic diseases. LIVNate is being developed to treat NASH. NASH is a pleiotropic disease caused
  by a complex mix of metabolic, inflammatory and fibrotic pathophysiology. We believe targeting inflammation caused by intestinal
  leak, mesenteric and peripheral fat will prevent lipotoxicity, hepatic stellate cell activation and hepatocyte death that causes
  fibrosis and liver dysfunction associated with advanced disease. sTNF is elevated in obesity and is believed to cause intestinal
  leak. Intestinal leak combined with cytokines coming from mesenteric fat may dramatically increase the concentration of inflammatory
  cytokines in portal blood destined for the liver. The cytokine load contributes to the development of non-alcoholic fatty liver
  disease ("NAFLD") and progression to NASH. LIVNate, by neutralizing sTNF improves insulin sensitivity, decreases the
  inflammation in peripheral and mesenteric fat and may also seal the intestinal leak. This combination prevents development of NAFLD
  or NASH in animal models. The Company is planning a Phase II open label randomized study using non-invasive measures to enroll
  patients with NASH in a study using a fixed dose of LIVNate delivered as a once a week sub-cutaneous injection.
  We also believe the DN-TNF platform may
  be used to treat the complications associated with the cytokine storm caused by coronavirus disease 2019 ("COVID-19").
  Three inflammatory cytokines make up the cytokine storm associated with COVID19 infection – sTNF, IL-6 and IL-1β. Targeting
  sTNF with Quellor may have advantages because IL-6 and IL-1 expression occur after sTNF expression; sTNF promotes endothelial activation
  causing expression of proteins that promote trafficking of immune cells from the blood vessel to the tissue and expression of Tissue
  Factor that stimulates the coagulopathy that is a prominent pathology of COVID-19 infection. The Company plans a Phase II trial
  in patients with symptomatic COVID-19 infection and hypoxia. The goal of the study is to prevent the catastrophic complications
  of advanced COVID-19 infection including one or more of the need for mechanical ventilation, new onset of cardiovascular, neurologic
  or thromboembolic disease, admission to an intensive care unit or death. The randomized trial will treat patients requiring hospitalization
  because of their disease.
  Effective therapy for TRD is a large unmet
  need. Twenty percent of patients with a Major Depressive Disorder have TRD. Once third of TRD patients have peripheral biomarkers
  to inflammation (elevated CRP). This is a large patient population. The role of TNF and anti-TNF therapeutics was explored in a
  small open label clinical trial by Prof. Andrew Miller, MD of Emory University demonstrated the patients have elevated TNF levels
  and treatment with infliximab treated their depression (Miller, 2011). The Company received a $2.9M USD award from the National
  Institute of Mental Health ("NIMH") to treat TRD with XPro1595. The blinded, randomized Phase II trial will use a biomarkers
  of peripheral inflammation to select patients with TRD for enrollment. Patients will be treated for 6 weeks. Primary end-points
  include both clinical and neuroimaging measures. The final trial design has is ongoing and discussions with the FDA are not complete.
  The Company anticipates receiving authorization to initiate the clinical trial in the second half of 2021.
  We believe that INKmune improves the ability
  of the patient's own NK cells to attack their tumor. INKmune interacts with the patient's NK cells to convert them
  from inert resting NK cells that ignores the cancer into primed NK cells that kill the cancer cell. INKmune is a replication incompetent
  proprietary cell line we have named INB16 that is given to the patient after determining that i) the patient has adequate NK cells
  in their circulation and ii) those NK cells are functional when exposed to INKmune in vitro. INKmune is designed to be given to
  patients after their immune system has recovered after cytotoxic chemotherapy to target the residual disease the remains after
  treatment with cytotoxic therapy. INKmune can be used to treat numerous hematologic malignancies and solid tumors including leukemia,
  multiple myeloma, lymphoma, lung, ovary, breast, renal and prostate cancer. The Company plans Phase I trials using INKmune to treat
  patients with high risk MDS, a form of leukemia and women with relapsed refractory ovarian.
  7
  Corporate Information
  Our principal executive offices are located
  at 1200 Prospect Street, Suite 525, La Jolla, California 92037. Our telephone number is (858) 964-3720. We maintain an Internet
  website at www.inmunebio.com. The information contained on, connected to or that can be accessed via our website is not part of
  this prospectus. We have included our website address in this prospectus as an inactive textual reference only and not as an active
  hyperlink
  About
  This Offering
  This
  offering relates to the resale by the selling stockholders of up to 3,700,000 shares of common stock issued or issuable upon exercise
  of options issued pursuant to grants made pursuant to our 2017 Plan and 2019 Plan.
  RISK FACTORS
  Investing in our securities involves a
  high degree of risk. Before making an investment decision, you should consider carefully the risks, uncertainties and other factors
  described in our most recent Annual Report on Form 10-K, as supplemented and updated by subsequent quarterly reports on Form 10-Q
  and current reports on Form 8-K that we have filed or will file with the SEC
  You should carefully
  consider the factors discussed in Part I, Item 1A. "Risk Factors" in our annual report on Form 10-K
  for the year ended December 31, 2020. Except as set forth below, there have been no material changes from those risk
  factors. The risks discussed in our 2020 annual report and described below could materially affect our business, financial condition
  and future results.
  An occurrence of an uncontrollable event
  such as the COVID-19 pandemic may negatively affect our operations and ability to raise capital.
  The occurrence of an uncontrollable event
  such as the COVID-19 pandemic may negatively affect our operations. A pandemic typically results in social distancing, travel bans
  and quarantine, and this may limit access to our facilities, customers, management, support staff and professional advisors. These
  factors, in turn, may impact our operations and financial condition. Also, the pandemic may hamper our efforts to comply with our
  filing obligations with the Securities and Exchange Commission. We cannot presently predict the scope and severity of any potential
  business shutdowns or disruptions, but if we or any of the third parties with whom we engage, including the suppliers, clinical
  trial sites, regulators and other third parties with whom we conduct business, were to experience shutdowns or other business disruptions,
  our ability to conduct our business in the manner and on the timelines presently planned could be materially and negatively impacted.
  Furthermore, if any of our key employees became ill or die as a result of COVID-19, it could negatively impact our business. 
  It is also possible that global health concerns such as this one could disproportionately impact the clinical sites in which we
  conduct any of our clinical trials, which could have a material adverse effect on our business and our results of operation and
  financial condition. The COVID-19 pandemic, may also negatively impact the Company's ability to raise capital.
  8
  CAUTIONARY NOTE REGARDING FORWARD-LOOKING
  STATEMENTS
  This prospectus and the documents and information
  incorporated by reference in this prospectus contain certain forward-looking statements within the meaning of the Private Securities
  Litigation Reform Act of 1995. For this purpose, any statements contained in this prospect and the documents and information incorporated
  by reference in this prospectus that are not statements of historical fact may be deemed to be forward-looking statements. Without
  limiting the foregoing, words such as "may," "will," "expect," "believe," "anticipate,"
  "estimate" or "continue" or comparable terminology are intended to identify forward-looking statements.
  These statements by their nature involve substantial risks and uncertainties, and actual results may differ materially depending
  on a variety of factors, many of which are not within our control. These factors include but are not limited to economic conditions
  generally and in the industries in which we may participate; competition within our chosen industry, including competition from
  much larger competitors; technological advances and failure to successfully develop business relationships.
  USE OF PROCEEDS
  We will not receive any
  proceeds from the sale of shares of common stock offered by the selling stockholders.
  SELLING STOCKHOLDERS
  This
  offering relates to the resale by the selling stockholders who have received or acquired, or may hereafter receive or acquire,
  the shares pursuant to the Plans. The selling stockholders may resell all, a portion, or none of the shares of common stock from
  time to time.
  The following table sets forth, based on
  information provided to us by the selling stockholders or known to us, the name of each selling stockholder, the nature of any
  position, office or other material relationship, if any, which the selling stockholder has had, within the past three years, with
  us or with any of our predecessors or affiliates, and the number of shares of our common stock beneficially owned by the selling
  stockholder before this offering. Except as otherwise indicated, the selling stockholders are past or present employees or
  consultants of the Company. The number of shares owned are those beneficially owned, as determined under the rules of the SEC,
  and the information is not necessarily indicative of beneficial ownership for any other purpose. Under these rules, beneficial
  ownership includes any shares of common stock as to which a person has sole or shared voting power or investment power and any
  shares of common stock which the person has the right to acquire within 60 days through the exercise of any option, warrant or
  right, through conversion of any security or pursuant to the automatic termination of a power of attorney or revocation of a trust,
  discretionary account or similar arrangement. None of the selling stockholders is a broker-dealer or an affiliate of a broker-dealer.
  Percentage of ownership is based on 14,932,638 shares of common stock outstanding on March 4, 2021.
  We have assumed all shares of common stock
  reflected on the table will be sold from time to time in the offering covered by this prospectus. Because the selling stockholders
  may offer all or any portion of the shares of common stock listed in the table below, no estimate can be given as to the amount
  of those shares of common stock covered by this prospectus that will actually be held by the selling stockholders upon the termination
  of the offering. Selling stockholders may choose not to sell any of the shares of common stock registered herein.
  9
  Number of Shares
  Beneficially Owned Prior to Offering (1)
  Number of Shares Being
  Number of Shares Beneficially Owned After
          Offering
  Selling Stockholder
  Position
  Number
  Percent (%)
  Offered
  Number
  Percent (%)
  Raymond J. Tesi
  President, CEO and Director
  2,082,594
  13.9
  %
  541,661
  (2)
  1,540,933
  10.3
  %
  David Moss
  CFO, Treasurer and Secretary
  1,765,078
  11.8
  %
  541,661
  (3)
  1,223,417
  8.2
  %
  Mark Lowdell
  CSO
  1,991,251
  13.3
  %
  485,000
  (4)
  1,506,251
  10.1
  %
  Christopher Barnum
  Head of Neuroscience
  94,467
  *
  94,467
  (5)
  -
  *
  Josh Schoonover
  Assoc. General Counsel
  85,000
  *
  85,000
  (6)
  -
  *
  Cory Ellspermann
  Controller and VP of Finance
  30,123
  *
  30,123
  (7)
  -
  *
  Scott Juda
  Director
  187,831
  1.3
  %
  160,331
  (8)
  27,500
  *
  Timothy Schroeder
  Director
  326,998
  2.2
  %
  160,331
  (9)
  166,667
  1.1
  %
  J. Kelly Ganjei
  Director
  160,331
  1.1
  %
  160,331
  (10)
  *
  Edgardo Baracchini
  Director
  52,331
  *
  52,331
  (11)
  *
  Marcia Allen
  Director
  52,331
  *
  52,331
  (12)
  *
  *
  Less than 1%
  (1)
  The securities
  "beneficially owned" by a person are determined in accordance with the definition of "beneficial ownership"
  set forth in the rules and regulations promulgated under the Exchange Act, and accordingly, may include securities owned by and
  for, among others, the spouse and/or minor children of an individual and any other relative who has the same home as such individual,
  as well as other securities as to which the individual has or shares voting or investment power or which such person has the right
  to acquire within 60 days of March 4, 2021 pursuant to the exercise of options, or otherwise.  Beneficial ownership may be
  disclaimed as to certain of the securities.
  (2)
  Includes:
  (a) options to purchase 400,000 shares of common stock exercisable by Mr. Tesi at an exercise price of $7.80 per share; and (b)
  options to purchase 141,661 shares of common stock exercisable by Mr. Tesi at an exercise price of $3.91 per share.
  (3)
  Includes:
  (a) options to purchase 400,000 shares of common stock exercisable by Mr. Moss at an exercise price of $7.80 per share; and (b)
  options to purchase 141,661 shares of common stock exercisable by Mr. Moss at an exercise price of $3.91 per share.
  (4)
  Includes:
  (a) options to purchase 400,000 shares of common stock exercisable by Mr. Lowdell at an exercise price of $7.80 per share; and
  (b) options to purchase 85,000 shares of common stock exercisable by Mr. Lowdell at an exercise price of $3.91 per share.
  (5)
  Includes
  options to purchase 94,467 shares of common stock exercisable by Mr. Barnum at an exercise price of $3.91 per share.
  10
  (6)
  Includes
  options to purchase 85,000 shares of common stock exercisable by Mr. Schoonover at an exercise price of $3.91 per share.
  (7)
  Includes
  options to purchase 30,123 shares of common stock exercisable by Mr. Ellspermann at an exercise price of $3.91 per share.
  (8)
  Includes:
  (a) options to purchase 108,000 shares of common stock exercisable by Mr. Juda at an exercise price of $7.80 per share; (b) options
  to purchase 51,000 shares of common stock exercisable by Mr. Juda at an exercise price of $3.91 per share; and (c) options to purchase
  1,331 shares of common stock exercisable by Mr. Juda at an exercise price of $24.82 per share.
  (9)
  Includes:
  (a) options to purchase 108,000 shares of common stock exercisable by Mr. Schroeder at an exercise price of $7.80 per share; (b)
  options to purchase 51,000 shares of common stock exercisable by Mr. Schroeder at an exercise price of $3.91 per share; and (c)
  options to purchase 1,331 shares of common stock exercisable by Mr. Schroeder at an exercise price of $24.82 per share.
  (10)
  Includes:
  (a) options to purchase 108,000 shares of common stock exercisable by Mr. Ganjei at an exercise price of $7.80 per share; (b) options
  to purchase 51,000 shares of common stock exercisable by Mr. Ganjei at an exercise price of $3.91 per share; and (c) options to
  purchase 1,331 shares of common stock exercisable by Mr. Ganjei at an exercise price of $24.82 per share.
  (11)
  Includes:
  (a) options to purchase 51,000 shares of common stock exercisable by Mr. Baracchini at an exercise price of $3.91 per share; and
  (b) options to purchase 1,331 shares of common stock exercisable by Mr. Baracchini at an exercise price of $24.82 per share.
  (12)
  Includes:
  (a) options to purchase 51,000 shares of common stock exercisable by Mrs. Allen at an exercise price of $3.91 per share; and (b)
  options to purchase 1,331 shares of common stock exercisable by Mrs. Allen at an exercise price of $24.82 per share.
  PLAN OF DISTRIBUTION
  Timing of Sales
  The
  selling stockholders may offer and sell the shares covered by this prospectus at various times. The selling stockholders will act
  independently of our company in making decisions with respect to the timing, manner and size of each sale.
  To our knowledge, no selling stockholder
  has any agreement or understanding, directly or indirectly, with any person to resell the shares of common stock covered by this
  prospectus.
  11
  Offering Price
  The sales price offered by the selling
  stockholders to the public may be:
  1.
  the market price prevailing at the time of sale;
  2.
  a price related to such prevailing market price; or
  3.
  such other price as the selling stockholders determine from time to time.
  Manner of Sale
  The shares of common stock may be sold
  by means of one or more of the following methods:
  1.
  a block trade in which the broker-dealer so engaged will attempt to sell the shares of common stock as agent, but may position and resell a portion of the block as principal to facilitate the transaction;
  2.
  purchases by a broker-dealer as principal and resale by that broker-dealer for its account pursuant to this prospectus;
  3.
  ordinary brokerage transactions in which the broker solicits purchasers;
  4.
  through options, swaps or derivatives;
  5.
  in transactions to cover short sales;
  6.
  privately negotiated transactions; or
  7.
  in a combination of any of the above methods.
  The selling stockholders may sell their
  shares of common stock directly to purchasers or may use brokers, dealers, underwriters or agents to sell their shares of common
  stock. Brokers or dealers engaged by the selling stockholders may arrange for other brokers or dealers to participate. Brokers
  or dealers may receive commissions, discounts or concessions from the selling stockholders, or, if any such broker-dealer acts
  as agent for the purchaser of shares of common stock, from the purchaser in amounts to be negotiated immediately prior to the sale.
  The compensation received by brokers or dealers may, but is not expected to, exceed that which is customary for the types of transactions
  involved.
  Broker-dealers may agree with a selling
  stockholder to sell a specified number of shares of common stock at a stipulated price per common share, and, to the extent the
  broker-dealer is unable to do so acting as agent for a selling stockholder, to purchase as principal any unsold shares of common
  stock at the price required to fulfill the broker-dealer commitment to the selling stockholder.
  Broker-dealers who acquire shares of common
  stock as principal may thereafter resell the shares of common stock from time to time in transactions, which may involve block
  transactions and sales to and through other broker-dealers, including transactions of the nature described above, on the NASDAQ
  Capital Market or otherwise at prices and on terms then prevailing at the time of sale, at prices then related to the then-current
  market price or in negotiated transactions. In connection with resales of the shares of common stock, broker-dealers may pay to
  or receive from the purchasers of shares commissions as described above.
  12
  If the selling stockholders enter into
  arrangements with brokers or dealers, as described above, we are obligated to file a post-effective amendment to this registration
  statement disclosing such arrangements, including the names of any broker-dealers acting as underwriters.
  The selling stockholders and any broker-dealers
  or agents that participate with the selling stockholders in the sale of the shares of common stock may be deemed to be "underwriters"
  within the meaning of the Securities Act. In that event, any commissions received by broker-dealers or agents and any profit on
  the resale of the shares of common stock purchased by them may be deemed to be underwriting commissions or discounts under the
  Securities Act.
  Sales Pursuant to Rule 144
  Any shares of common stock covered by this
  prospectus which qualify for sale pursuant to Rule 144 under the Securities Act may be sold under Rule 144 rather than pursuant
  to this prospectus.
  Regulation M
  The selling stockholders must comply with
  the requirements of the Securities Act and the Securities Exchange Act of 1934, as amended (the "Exchange Act") in
  the offer and sale of the common stock. In particular we will advise the selling stockholders that the anti-manipulation rules
  of Regulation M under the Exchange Act may apply to sales of shares of common stock in the market and to the activities of
  the selling stockholders and their affiliates. Regulation M under the Exchange Act prohibits, with certain exceptions, participants
  in a distribution from bidding for, or purchasing for an account in which the participant has a beneficial interest, any of the
  securities that are the subject of the distribution.
  Accordingly, during such times as a selling
  stockholder may be deemed to be engaged in a distribution of the common stock, and therefore be considered to be an underwriter,
  the selling stockholder must comply with applicable law and, among other things:
  1.
  may not engage in any stabilization activities in connection with our common stock;
  2.
  may not cover short sales by purchasing shares while the distribution is taking place; and
  3.
  may not bid for or purchase any of our securities or attempt to induce any person to purchase any of our securities other than as permitted under the Exchange Act.
  In addition, we will make copies of this
  prospectus available to the selling stockholders for the purpose of satisfying the prospectus delivery requirements of the Securities
  Act.
  State Securities Laws
  Under the securities laws of some states,
  the shares of common stock may be sold in such states only through registered or licensed brokers or dealers. In addition, in some
  states the shares of common stock may not be sold unless the shares have been registered or qualified for sale in the state or
  an exemption from registration or qualification is available and is complied with.
  Expenses of Registration
  We are bearing all costs relating to the
  registration of the common stock. The selling stockholders, however, will pay any commissions or other fees payable to brokers
  or dealers in connection with any sale of the common stock.
  13
  LEGAL MATTERS
  The validity of the common stock has been
  passed upon by Sichenzia Ross Ference LLP, New York, New York.
  EXPERTS
  The consolidated financial statements of
  INmune Bio Inc. as of and for the years ended December 31, 2020 and December 31, 2019 appearing in INmune Bio Inc.'s
  Annual Report on Form 10-K for the year ended December 31, 2020, have been audited by Marcum LLP, as set forth in its report
  thereon, included therein, and incorporated herein by reference. Such consolidated financial statements are incorporated herein
  by reference in reliance upon such report given on the authority of such firm as experts in accounting and auditing.
  INCORPORATION
  OF CERTAIN DOCUMENTS by Reference
  The Securities and Exchange Commission,
  or SEC, allows us to incorporate by reference certain of our publicly filed documents into this prospectus, which means that such
  information is considered part of this prospectus. Information that we file with the SEC subsequent to the date of this prospectus
  will automatically update and supersede this information. We incorporate by reference the documents listed below and any future
  filings made with the SEC under all documents subsequently filed by us pursuant to Section 13(a), 13(c), 14 or 15(d) of the Exchange
  Act until the selling stockholders have sold all of the shares offered hereby or such shares have been deregistered.
  ·
  our Annual Report on Form
  10-K
  for the fiscal
      year ended December 31, 2020, filed with the SEC on March 4, 2021;
  ·
  our Annual Report on Form
  10-K
  for the fiscal
      year ended December 31, 2019, filed with the SEC on March 11, 2020;
  ·
  our Quarterly Report on Form
  10-Q
  for the period ended March 31, 2020, filed with the SEC May 14, 2020;
  ·
  our Quarterly Report on Form
  10-Q
  for the period ended June 30, 2020, filed with the SEC August 5, 2020;
  ·
  our Quarterly Report on Form
  10-Q
  for the period ended September 30, 2020, filed with the SEC on November 5, 2020;
  ·
  our Current Reports on Form 8-K or Form 8-K/A
      filed with the SEC on
  March 12, 2020
  ,
  April 9, 2020
  ,
  April 17, 2020
  ,
  April
      21, 2020
  ,
  April 21, 2020
  ,
  April 22, 2020
  ,
  April 23, 2020
  ,
  April 28, 2020
  ,
  May 5, 2020
  ,
  May 7, 2020
  ,
  May 12, 2020
  ,
  May
      15, 2020
  ,
  May 18, 2020
  ,
  June 15, 2020
  ,
  July 10, 2020
  ,
  July 13, 2020
  ,
  July 16, 2020
  ,
  July 20, 2020
  ,
  July 21, 2020
  ,
  July
      28, 2020
  ,
  July 30, 2020
  ,
  August 3, 2020
  ,
  August 6, 2020
  ,
  August 7, 2020
  ,
  August 14, 2020
  ,
  August 19, 2020
  ,
  September 3, 2020
  ,
  September 4, 2020
  ,
  September 15, 2020
  ,
  September 17, 2020
  ,
  September 24, 2020
  ,
  September 29 ,2020
  ,
  October 1, 2020
  ,
  October 6, 2020
  ,
  October 27, 2020
  ;
  November 6, 2020
  ,
  November 9, 2020
  ,
  November 12, 2020
  ,
  December 30, 2020
  ,
  December 30, 2020
  ,
  January 4, 2021
  ,
  January 21, 2021
  ,
  January 21, 2021
  ,
  January 25, 2021,
  March 2, 2021
  ,
  March 5, 2011
  ,
  March 9, 2011
  and
  March 11, 2021
  ;
  ·
  our
  Definitive Proxy Statement
  on Schedule 14A filed with the SEC on August 21, 2020; and
  ·
  the description of our common stock, which is contained in the registration statement on
  Form 8-A
  filed with the SEC on February 1, 2019 (File No. 001-38793), including any amendments or reports filed for the purpose of updating that description.
  Notwithstanding the foregoing, information
  furnished under Items 2.02 and 7.01 of any Current Report on Form 8-K, including the related exhibits, is not incorporated by reference
  in this Registration Statement.
  14
  Disclosure
  Of Commission Position On Indemnification
  For
  Securities Act Liabilities
  NRS 78.7502(1) provides that a corporation
  may indemnify any person who was or is a party or is threatened to be made a party to any threatened, pending or completed action,
  suit or proceeding, whether civil, criminal, administrative or investigative, except an action by or in the right of the corporation,
  by reason of the fact that he is or was a director, officer, employee or agent of the corporation, or is or was serving at the
  request of the corporation as a director, officer, employee or agent of another corporation, partnership, joint venture, trust
  or other enterprise, against expenses, including attorneys' fees, judgments, fines and amounts paid in settlement actually and
  reasonably incurred by him in connection with the action, suit or proceeding if he: (a) is not liable pursuant to NRS 78.138; or
  (b) acted in good faith and in a manner which he reasonably believed to be in or not opposed to the best interests of the corporation,
  and, with respect to any criminal action or proceeding, had no reasonable cause to believe his conduct was unlawful.
  NRS Section
  78.7502(2) provides that a corporation may indemnify any person who was or is a party or is threatened to be made a party to any
  threatened, pending or completed action or suit by or in the right of the corporation to procure a judgment in its favor by reason
  of the fact that he is or was a director, officer, employee or agent of the corporation, or is or was serving at the request of
  the corporation as a director, officer, employee or agent of another corporation, partnership, joint venture, trust or other enterprise
  against expenses, including amounts paid in settlement and attorneys' fees actually and reasonably incurred by him in connection
  with the defense or settlement of the action or suit if he: (a) is not liable pursuant to NRS 78.138; or (b) acted in good faith
  and in a manner which he reasonably believed to be in or not opposed to the best interests of the corporation. Indemnificatio
  n
  may not be made for any claim, issue or matter as to which such a person has been adjudged by a court
  of competent jurisdiction, after exhaustion of all appeals there from, to be liable to the corporation or for amounts paid in settlement
  to the corporation, unless and only to the extent that the court in which the action or suit was brought or other court of competent
  jurisdiction determines upon application that in view of all the circumstances of the case, the person is fairly and reasonably
  entitled to indemnity for such expenses as the court deems proper.
  Our
  Articles of Incorporation provides that very person who was or is a party to, or is threatened to be made a party to, or is involved
  in any action, suit or proceeding, whether civil, criminal, administrative or investigative, by reason of the fact that he, or
  a person of whom he is the legal representative, is or was a director or officer of the Company, or is or was serving at the request
  of the Company as a director or officer of another corporation, or as its representative in a partnership, joint venture, trust
  or other enterprise, shall be indemnified and held harmless to the fullest extent legally permissible under the laws of the State
  of Nevada from time to time against all expenses, liability and loss (including attorney's fees, judgements, fines and amounts
  paid or to be paid in settlement) reasonably incurred or suffered by him in connection therewith. Such right of indemnification
  shall be a contract right which may be enforced in any matter desired by such person. The expenses of the officers and directors
  incurred in defending a civil or criminal action, suit or proceeding must be paid by the Company as they are incurred and in advance
  of the final disposition of the action, suit or proceeding, upon receipt of an undertaking by or on behalf of the director or officer
  to repay the amount if it is ultimately determined by a court of competent jurisdiction that he is not entitled to be indemnified
  by the Company. Such right of indemnification shall not be exclusive of any other right which such directors, officers or representatives
  may have or hereafter acquire, and, without limiting the generality of such statement, they shall be entitled to their respective
  rights of indemnification under any bylaw, agreement, vote of stockholders, provision of law, or otherwise, as well as their rights
  under this Article.
  NRS Section 78.747 provides that except
  as otherwise provided by specific statute, no director or officer of a corporation is individually liable for a debt or liability
  of the corporation, unless the director or officer acts as the alter ego of the corporation. The court as a matter of law must
  determine the question of whether a director or officer acts as the alter ego of a corporation.
  Insofar as indemnification for liabilities
  arising under the Securities Act may be permitted to directors, offices or controlling persons of ours, pursuant to the foregoing
  provisions, or otherwise, we have been advised that, in the opinion of the Securities and Exchange Commission, such indemnification
  is against public policy as expressed in the Securities Act, and is, therefore, unenforceable. In the event that a claim for indemnification
  against such liabilities (other than the payment by us of expenses incurred or paid by a director, officer or controlling person
  of ours in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person
  in connection with the securities being registered hereunder, we will, unless in the opinion of our counsel the matter has been
  settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by us
  is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.
  15
  Additional
  Information Available to You
  This prospectus is part of a Registration
  Statement on Form S-8 that we filed with the SEC. Certain information in the Registration Statement has been omitted from this
  prospectus in accordance with the rules of the SEC. We file annual, quarterly and special reports, proxy statements and other information
  with the SEC. You can inspect and copy the Registration Statement as well as reports, proxy statements and other information we
  have filed with the SEC at the public reference room maintained by the SEC at 100 F Street N.E. Washington, D.C. 20549, You can
  obtain copies from the public reference room of the SEC at 100 F Street N.E. Washington, D.C. 20549, upon payment of certain fees.
  You can call the SEC at 1-800-732-0330 for further information about the public reference room. We are also required to file electronic
  versions of these documents with the SEC, which may be accessed through the SEC's World Wide Web site at http://www.sec.gov.
  No dealer, salesperson or other person is authorized to give any information or to make any representations other than those contained
  in this prospectus, and, if given or made, such information or representations must not be relied upon as having been authorized
  by us. This prospectus does not constitute an offer to buy any security other than the securities offered by this prospectus, or
  an offer to sell or a solicitation of an offer to buy any securities by any person in any jurisdiction where such offer or solicitation
  is not authorized or is unlawful. Neither delivery of this prospectus nor any sale hereunder shall, under any circumstances, create
  any implication that there has been no change in the affairs of our company since the date hereof.
  PART II
  INFORMATION REQUIRED IN THE REGISTRATION
  STATEMENT
  Item 3. Incorporation of Documents by
  Reference.
  The Company hereby incorporates by reference
  into this Registration Statement the documents listed below. In addition, all documents subsequently filed pursuant to Sections
  13(a), 13(c), 14 and 15(d) of the Exchange Act, prior to the filing of a post-effective amendment which indicates that all securities
  offered have been sold or which deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference
  into this Registration Statement and to be a part hereof from the date of filing of such documents.
  ·
  our Annual Report on Form
  10-K
  for the fiscal
      year ended December 31, 2020, filed with the SEC on March 4, 2021;
  ·
  our Annual Report on Form
  10-K
  for the fiscal
      year ended December 31, 2019, filed with the SEC on March 11, 2020;
  ·
  our Quarterly Report on Form
  10-Q
  for the period ended March 31, 2020, filed with the SEC May 14, 2020;
  ·
  our Quarterly Report on Form
  10-Q
  for the period ended June 30, 2020, filed with the SEC August 5, 2020;
  ·
  our Quarterly Report on Form
  10-Q
  for the period ended September 30, 2020, filed with the SEC on November 5, 2020;
  ·
  our Current Reports on Form 8-K or Form 8-K/A
      filed with the SEC on
  March 12, 2020
  ,
  April 9, 2020
  ,
  April 17, 2020
  ,
  April
      21, 2020
  ,
  April 21, 2020
  ,
  April 22, 2020
  ,
  April 23, 2020
  ,
  April 28, 2020
  ,
  May 5, 2020
  ,
  May 7, 2020
  ,
  May 12, 2020
  ,
  May
      15, 2020
  ,
  May 18, 2020
  ,
  June 15, 2020
  ,
  July 10, 2020
  ,
  July 13, 2020
  ,
  July 16, 2020
  ,
  July 20, 2020
  ,
  July 21, 2020
  ,
  July 28, 2020
  ,
  July 30, 2020
  ,
  August 3, 2020
  ,
  August 6, 2020
  ,
  August 7, 2020
  ,
  August 14, 2020
  ,
  August 19, 2020
  ,
  September 3, 2020
  ,
  September 4, 2020
  ,
  September 15, 2020
  ,
  September 17, 2020
  ,
  September 24, 2020
  ,
  September 29 ,2020
  ,
  October 1, 2020
  ,
  October 6, 2020
  ,
  October 27, 2020
  ;
  November 6, 2020
  ,
  November 9, 2020
  ,
  November 12, 2020
  ,
  December 30, 2020
  ,
  December 30, 2020
  ,
  January 4, 2021
  ,
  January 21, 2021
  ,
  January 21, 2021
  ,
  January 25, 2021
  ,
  March 2, 2021
  ,
  March 5, 2021
  ,
  March 9, 2021
  and
  March 11, 2021
  ;
  ·
  our
  Definitive Proxy Statement
  on Schedule 14A filed with the SEC on August 21, 2020; and
  ·
  the description of our common stock, which is contained in the registration statement on Form
  8-A
  filed with the SEC on February 1, 2019 (File No. 001-38793), including any amendments or reports filed for the purpose of updating that description.
  Notwithstanding the foregoing, information
  furnished under Items 2.02 and 7.01 of any Current Report on Form 8-K, including the related exhibits, is not incorporated by reference
  in this Registration Statement.
  Item 4. Description of Securities.
  Not applicable.
  Item 5. Interests of Named Experts and
  Counsel.
  None.
  16
  Item 6. Indemnification of Directors
  and Officers.
  NRS 78.7502(1) provides that a corporation
  may indemnify any person who was or is a party or is threatened to be made a party to any threatened, pending or completed action,
  suit or proceeding, whether civil, criminal, administrative or investigative, except an action by or in the right of the corporation,
  by reason of the fact that he is or was a director, officer, employee or agent of the corporation, or is or was serving at the
  request of the corporation as a director, officer, employee or agent of another corporation, partnership, joint venture, trust
  or other enterprise, against expenses, including attorneys' fees, judgments, fines and amounts paid in settlement actually and
  reasonably incurred by him in connection with the action, suit or proceeding if he: (a) is not liable pursuant to NRS 78.138; or
  (b) acted in good faith and in a manner which he reasonably believed to be in or not opposed to the best interests of the corporation,
  and, with respect to any criminal action or proceeding, had no reasonable cause to believe his conduct was unlawful.
  NRS Section
  78.7502(2) provides that a corporation may indemnify any person who was or is a party or is threatened to be made a party to any
  threatened, pending or completed action or suit by or in the right of the corporation to procure a judgment in its favor by reason
  of the fact that he is or was a director, officer, employee or agent of the corporation, or is or was serving at the request of
  the corporation as a director, officer, employee or agent of another corporation, partnership, joint venture, trust or other enterprise
  against expenses, including amounts paid in settlement and attorneys' fees actually and reasonably incurred by him in connection
  with the defense or settlement of the action or suit if he: (a) is not liable pursuant to NRS 78.138; or (b) acted in good faith
  and in a manner which he reasonably believed to be in or not opposed to the best interests of the corporation. Indemnificatio
  n
  may not be made for any claim, issue or matter as to which such a person has been adjudged by a court
  of competent jurisdiction, after exhaustion of all appeals there from, to be liable to the corporation or for amounts paid in settlement
  to the corporation, unless and only to the extent that the court in which the action or suit was brought or other court of competent
  jurisdiction determines upon application that in view of all the circumstances of the case, the person is fairly and reasonably
  entitled to indemnity for such expenses as the court deems proper.
  Our
  Articles of Incorporation provides that very person who was or is a party to, or is threatened to be made a party to, or is involved
  in any action, suit or proceeding, whether civil, criminal, administrative or investigative, by reason of the fact that he, or
  a person of whom he is the legal representative, is or was a director or officer of the Company, or is or was serving at the request
  of the Company as a director or officer of another corporation, or as its representative in a partnership, joint venture, trust
  or other enterprise, shall be indemnified and held harmless to the fullest extent legally permissible under the laws of the State
  of Nevada from time to time against all expenses, liability and loss (including attorney's fees, judgements, fines and amounts
  paid or to be paid in settlement) reasonably incurred or suffered by him in connection therewith. Such right of indemnification
  shall be a contract right which may be enforced in any matter desired by such person. The expenses of the officers and directors
  incurred in defending a civil or criminal action, suit or proceeding must be paid by the Company as they are incurred and in advance
  of the final disposition of the action, suit or proceeding, upon receipt of an undertaking by or on behalf of the director or officer
  to repay the amount if it is ultimately determined by a court of competent jurisdiction that he is not entitled to be indemnified
  by the Company. Such right of indemnification shall not be exclusive of any other right which such directors, officers or representatives
  may have or hereafter acquire, and, without limiting the generality of such statement, they shall be entitled to their respective
  rights of indemnification under any bylaw, agreement, vote of stockholders, provision of law, or otherwise, as well as their rights
  under this Article.
  NRS Section 78.747 provides that except
  as otherwise provided by specific statute, no director or officer of a corporation is individually liable for a debt or liability
  of the corporation, unless the director or officer acts as the alter ego of the corporation. The court as a matter of law must
  determine the question of whether a director or officer acts as the alter ego of a corporation.
  Insofar as indemnification for liabilities
  arising under the Securities Act may be permitted to directors, offices or controlling persons of ours, pursuant to the foregoing
  provisions, or otherwise, we have been advised that, in the opinion of the Securities and Exchange Commission, such indemnification
  is against public policy as expressed in the Securities Act, and is, therefore, unenforceable. In the event that a claim for indemnification
  against such liabilities (other than the payment by us of expenses incurred or paid by a director, officer or controlling person
  of ours in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person
  in connection with the securities being registered hereunder, we will, unless in the opinion of our counsel the matter has been
  settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by us
  is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.
  17
  Item 7. Exemption from Registration
  Claimed.
  Not applicable.
  Item 8. Exhibits.
  Exhibit Number
  Description
  5.1
  Opinion of Sichenzia Ross Ference LLP*
  23.1
  Consent of Marcum LLP*
  23.2
  Consent of Sichenzia Ross Ference LLP (included in Exhibit 5.1)*
  24.1
  Power of Attorney (included on the signature page)
  99.1
  INmune Bio Inc. 2017 Stock Incentive Plan
  99.2
  INmune Bio Inc. 2019 Stock Incentive Plan
  *
  Filed herewith
  Item 9. Undertakings.
  (a)
  The Company hereby undertakes:
  (1)
  To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:
  (i)
  To include any prospectus required by Section 10(a)(3) of the Securities Act.
  (ii)
  To reflect in the prospectus any facts or events arising after the effective date of the Registration Statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the Registration Statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities offered  would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus filed with the Securities and Exchange Commission pursuant to Rule 424(b) if, in the aggregate, the changes in volume and price represent no more than 20 percent change in the maximum aggregate offering price set forth in the "Calculation of Registration Fee" table in the effective Registration Statement.
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  (iii)
  To include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement or any material change to such information in the Registration Statement; provided, however, that (A) paragraphs (a)(1)(i) and (a)(1)(ii) of this section do not apply if the Registration Statement is on Form S–8 (§239.16b of Regulation S-K), and the information required to be included in a post-effective amendment by those paragraphs is contained in reports filed with or furnished to the Securities and Exchange Commission by the Company pursuant to section 13 or section 15(d) of the Exchange Act (15 U.S.C. 78m or 78o(d)) that are incorporated by reference in the Registration Statement; and (B) paragraphs (a)(1)(i), (a)(1)(ii) and (a)(1)(iii) do not apply if the Registration Statement is on Form S-3 or Form F-3, and the information required to be included in a post-effective amendment by those paragraphs is contained in reports filed with or furnished to the Securities and Exchange Commission by the Company pursuant to Section 13 or Section 15(d) of the Exchange Act that are incorporated by reference in the Registration Statement, or is contained in a form of prospectus filed pursuant to Rule 424(b) that is part of the Registration Statement; provided further, however, that paragraphs (a)(1)(i) and (a)(1)(ii) do not apply if the Registration Statement is for an offering of asset-backed securities on Form S-1 or Form S-3, and the information required to be included in a post-effective amendment is provided pursuant to Item 1100(c) of Regulation AB.
  (2)
  That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.
  (3)
  To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.
  (4)
  That, for the purpose of determining liability under the Securities Act of 1933 to any purchaser:
  (A) Each prospectus
  filed by a Registrant pursuant to Rule 424(b)(3) shall be deemed to be part of the registration statement as of the date the
  filed prospectus was deemed part of and included in the registration statement; and
  (B) Each prospectus
  required to be filed pursuant to Rule 424(b)(2), (b)(5) or (b)(7) as part of a registration statement in reliance on Rule 430B
  relating to an offering made pursuant to Rule 415(a)(1)(i),  (vii) or (x) for the purpose of providing
  the information required by Section 10(a) of the Securities Act of 1933 shall be deemed to be part of and included in the registration
  statement as of the earlier of the date such form of prospectus is first used after effectiveness or the date of the first contract
  of sale of securities in the offering described in the prospectus. As provided in Rule 430B, for liability purposes of the
  issuer and any person that is at that date an underwriter, such date shall be deemed to be a new effective date of the registration
  statement relating to the securities in the registration statement to which the prospectus relates, and the offering of such securities
  at that time shall be deemed to be the initial bona fide offering thereof. Provided, however, that no statement made in a registration
  statement or prospectus that is part of the registration statement or made in a document incorporated or deemed incorporated by
  reference into the registration statement or prospectus that is part of the registration statement will, as to a purchaser with
  a time of contract of sale prior to such effective date, supersede or modify any statement that was made in the registration statement
  or prospectus that was part of the registration statement or made in any such document immediately prior to such effective date.
  (b)
  The Company hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the Company's annual report pursuant to Section 13(a) or Section 15(d) of the Exchange Act that is incorporated by reference in this Registration Statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.
  (c)
  Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the Company pursuant to the foregoing provisions, or otherwise, the Company has been advised that in the opinion of the Securities and Exchange Commission such indemnification is against public policy as expressed in the Securities Act, and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the Company of expenses incurred or paid by a director, officer or controlling person of the Company in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered, the Company will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.
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  SIGNATURES
  Pursuant
  to the requirements of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it
  meets all of the requirements for filing on Form S-8 and has duly caused this registration statement to be signed on its behalf
  by the undersigned, thereunto duly authorized, in the City of La Jolla, State of California, on March 22, 2021
  INmune Bio Inc.
  /s/ Raymond J. Tesi
  Raymond J. Tesi, M. D.
  Chief Executive Officer
  (Principal Executive Officer)
  /s/ David J. Moss
  David J. Moss
  Chief Financial Officer
  (Principal Financial and Accounting Officer)
  INMUNE BIO INC.
  By:
  /s/ Raymond J. Tesi
  Raymond J. Tesi
  Its:
  Chief Executive Officer
  (Principal Executive Officer)
  By:
  /s/ David J. Moss
  David J. Moss
  Its:
  Chief Financial Officer
  (Principal Financial and Accounting Officer)
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  Each person whose signature appears below
  constitutes and appoints Raymond J. Tesi and David J. Moss, and each of them severally, as his true and lawful attorney in fact
  and agent, with full powers of substitution and re-substitution, for him and in his name, place and stead, in any and all capacities,
  to sign any or all amendments (including post effective amendments) to the Registration Statement, and to sign any registration
  statement for the same offering covered by this Registration Statement that is to be effective upon filing pursuant to Rule 462(b)
  under the Securities Act of 1933, as amended, and all post effective amendments thereto, and to file the same, with all exhibits
  thereto, and all documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorney-in-fact
  and agent, each acting alone, full power and authority to do and perform each and every act and thing requisite and necessary to
  be done in and about the premises, as fully to all intents and purposes as he or she might or could do in person, hereby ratifying
  and confirming all that said attorney-in-fact and agent, each acting alone, or his or her substitute or substitutes, may lawfully
  do or cause to be done by virtue hereof.
  Pursuant to the requirements of the Securities
  Act of 1933, this registration statement has been signed below by the following persons in the capacities and on the dates indicated.
  /s/ Raymond J. Tesi
  March 22, 2021
  Raymond J. Tesi, M.D.
  Chief Executive Officer and
  Director (principal executive officer)
  /s/ David J. Moss
  March 22, 2021
  David J. Moss
  Chief Financial Officer
  (principal financial and accounting officer)
  /s/ Timothy Schroeder
  March 22, 2021
  Timothy Schroeder
  Director
  /s/ David Szymkowski
  March 22, 2021
  David Szymkowski
  Director
  /s/ J. Kelly Ganjei
  March 22, 2021
  J. Kelly Ganjei
  Director
  /s/ Scott Juda, JD
  March 22, 2021
  Scott Juda, JD
  Director
  /s/ Edgardo Baracchini
  March 22, 2021
  Edgardo Baracchini
  Director
  /s/ Marcia Allen
  March 22, 2021
  Marcia Allen
  Director
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