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      <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><b><font size=2>As filed with the Securities and Exchange Commission on September 23, 2005</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:3pt; text-indent:0.5in;text-align:right;'><b><font size=2>Registration No. 333-</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; text-indent:0.5in;text-align:center;border-top:solid 0.75pt;padding-top:1;'><font size=2>&nbsp;</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font SIZE=2>SECURITIES AND EXCHANGE COMMISSION</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font size=2>Washington, D.C. 20549</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font size=2>______________________</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:6pt; margin-left:0.5in;text-align:center;'><b><font SIZE=2>FORM S-8</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font SIZE=2>REGISTRATION STATEMENT</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font SIZE=2>UNDER</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font SIZE=2>THE SECURITIES ACT OF 1933</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font size=2>______________________</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:3pt; margin-left:0.5in;text-align:center;'><b><font SIZE=2>SYNTHETECH,</font></b><font size=2>&nbsp;</font><b><font SIZE=2>INC.</font></b></p>
  
      <p style=' margin-bottom:3pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><font size=2>(Exact name of Registrant as specified in its charter)</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>&nbsp;</font></p>
  
      <table border="0" cellspacing=0 cellpadding=0 width="92%" align=center style='border-collapse:collapse'>
          <tr style='page-break-inside:avoid'>
              <td width="50%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:0pt;margin-bottom:0pt;line-height:64.8%'><b><font size=2>Oregon</font></b><b></b></p> </td>
              <td width="49%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:0pt;margin-bottom:0pt;line-height:64.8%'><b><font size=2>84-0845771</font></b><b></b></p> </td> </tr>
          <tr style='page-break-inside:avoid'>
              <td width="50%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:0pt;margin-bottom:0pt'><font size=2>(State or other jurisdiction of incorporation or organization)</font></p> </td>
              <td width="49%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:0pt;margin-bottom:0pt'><font size=2>(I.R.S. Employer Identification No.)</font></p> </td> </tr></table>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><font size=2>&nbsp;</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; margin-left:0.5in;text-align:center;'><b><font size=2>1290 Industrial Way</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font size=2>Albany Oregon 97322</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font size=2>(541) 967-6575</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><font size=2>(Address of principal executive offices, including zip code)</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><font size=2>&nbsp;</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font SIZE=2>SYNTHETECH, INC. 2005 EQUITY INCENTIVE PLAN</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><font size=2>(Full title of the plan)</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><font size=2>&nbsp;</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font size=2>Gary Weber</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font size=2>1290 Industrial Way</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font size=2>Albany, Oregon 97322</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font size=2>(541) 967-6575</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><font size=2>(Name, address and telephone number, including area code, of agent for service)</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font size=2>______________________</font></b></p>
  
      <p style=' margin-bottom:3pt; margin-top:3pt; margin-left:0.5in;text-align:center;'><b><font size=2>Copies to:</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font size=2>David Matheson</font></b></p>
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font size=2>Perkins Coie LLP</font></b></p>
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font size=2>1120 NW Couch Street</font></b></p>
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font size=2>Portland, Oregon 97209</font></b></p>
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font size=2>(503) 727-2000</font></b></p>
  
      <p style=' margin-bottom:3pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font size=2>______________________</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><font size=2>&nbsp;</font></p>
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font SIZE=2>CALCULATION OF REGISTRATION FEE</font></b></p>
  
  
      <table border="0" cellspacing=0 cellpadding=0 width="100%" align=center style='margin-left:0pt;border-collapse:collapse'>
          <tr style='page-break-inside:avoid'>
              <td  width="35%" valign=top style='border:solid black 1.0pt;border-color:black; border-top:double black 2.25pt; padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:0pt;margin-bottom:0pt;line-height:64.8%'><br> <b><font size=2>Title of Securities</font></b><br> <b><font size=2>to Be Registered</font></b><b></b></p> </td>
              <td width="14%" valign=top style='border-top:double black 2.25pt; border-left:none;border-bottom:solid black 1.0pt;border-right:solid black 1.0pt;  padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:0pt;margin-bottom:0pt;line-height:64.8%'><br> <b><font size=2>Amount to Be</font></b><br> <b><font size=2>Registered (1)</font></b><b></b></p> </td>
              <td width="18%" valign=top style='border-top:double black 2.25pt; border-left:none;border-bottom:solid black 1.0pt;border-right:solid black 1.0pt;  padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:0pt;margin-bottom:0pt;line-height:64.8%'><b><font size=2>Proposed Maximum</font></b><br> <b><font size=2>Offering Price Per Share (2)</font></b><b></b></p> </td>
              <td width="19%" valign=top style='border-top:double black 2.25pt; border-left:none;border-bottom:solid black 1.0pt;border-right:solid black 1.0pt;  padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:0pt;margin-bottom:0pt;line-height:64.8%'><b><font size=2>Proposed Maximum</font></b><br> <b><font size=2>Aggregate Offering Price</font></b><b></b></p> </td>
              <td width="14%" valign=top style='border-top:double black 2.25pt; border-left:none;border-bottom:solid black 1.0pt;border-right:solid black 1.0pt;  padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:0pt;margin-bottom:0pt;line-height:64.8%'><b><font size=2>Amount of Registration Fee </font></b><b></b></p> </td>
  </tr>
          <tr style='page-break-inside:avoid'>
              <td  width="35%" valign=top style='border:solid black 1.0pt;border-color:black; border-top:none;padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:3.0pt;margin-bottom:0pt;line-height:97.2%'><font size=2>Common Stock, no par value, (including, any associated common stock purchase rights) under the Synthetech, Inc. 2005 Equity Incentive Plan </font></p> </td>
              <td width="14%" valign=top style='border-top:none;border-left: none;border-bottom:solid black 1.0pt;border-right:solid black 1.0pt;   padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:3pt;margin-bottom:3pt'><font size=2>952,975</font></p> </td>
              <td width="18%" valign=top style='border-top:none;border-left: none;border-bottom:solid black 1.0pt;border-right:solid black 1.0pt;   padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:3.0pt;margin-bottom:0pt;line-height:97.2%'><font size=2>$0.54 </font></p> </td>
              <td width="19%" valign=top style='border-top:none;border-left: none;border-bottom:solid black 1.0pt;border-right:solid black 1.0pt;   padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:3.0pt;margin-bottom:0pt;line-height:97.2%'><font size=2>$514,606.50</font></p> </td>
              <td width="14%" valign=top style='border-top:none;border-left: none;border-bottom:solid black 1.0pt;border-right:solid black 1.0pt;   padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:3.0pt;margin-bottom:0pt;line-height:97.2%'><font size=2>$60.57</font></p> </td>
  </tr>
          </table>
  
  <!-- MARKER FORMAT-SHEET="Para Hang" FSL="Default" -->
  <TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0>
  <TR VALIGN=TOP>
  <TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=1>(1)  </FONT></TD>
  <TD><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp; </FONT></TD>
  <TD WIDTH=95%><FONT FACE="Times New Roman, Times, Serif" SIZE=1>Includes
  an indeterminate number of additional shares that may be necessary to adjust the number
  of shares reserved for issuance pursuant to the plan as the result of any future stock
  split, stock dividend or similar adjustment of the Registrant's outstanding Common Stock.&nbsp; </FONT></TD>
  </TR>
  </TABLE>
  
  
  
  <!-- MARKER FORMAT-SHEET="Para Hang" FSL="Default" -->
  <TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0>
  <TR VALIGN=TOP>
  <TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=1>(2)  </FONT></TD>
  <TD><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp; </FONT></TD>
  <TD WIDTH=95%><FONT FACE="Times New Roman, Times, Serif" SIZE=1>Estimated
  solely for the purpose of calculating the registration fee pursuant to Rule&nbsp;457(c)
  and Rule 457(h) under the Securities Act.  The proposed maximum offering price per share
  is estimated to be $0.54 based on the average of the high ($0.58) and low ($0.50) sales
  prices for the Common Stock on September 19, 2005 as reported for such date on the Nasdaq
  SmallCap Market.  </FONT></TD>
  </TR>
  </TABLE>
  <BR>
  
      <p style='page-break-before:always'></p>
      <pAGE>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><b><font SIZE=2>PART II</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:6pt; margin-left:0.5in;text-align:center;'><b><font SIZE=2>INFORMATION REQUIRED IN REGISTRATION STATEMENT</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; margin-left:0.5in; text-indent:-0.5in;text-align:left;'><b><font size=2>Item 3.  INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>The following documents filed with the Securities and Exchange Commission are hereby incorporated by reference in this Registration Statement:</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:1in;text-align:left;'><font size=2>(a)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Registrant's Annual Report for the year ended March&nbsp;31, 2005 (filed on June 29, 2005), which contains audited financial statements for the most recent fiscal year for which such statements have been filed;</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:1in;text-align:left;'><font size=2>(b)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Registrant's Quarterly Report on Form 10-Q for the quarter ended June 30, 2005 (filed on August 4, 2005);</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:1in;text-align:left;'><font size=2>(c)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Registrant's Current Reports on Form 8-K, filed on May 26, 2005, August 26, 2005 and September 15, 2005; and </font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:1in;text-align:left;'><font size=2>(d)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The description of the Registrant's Common Stock contained in the Registrant's Registration Statement on Form&nbsp;8-A filed on November 8, 1984 under Section&nbsp;12(g) of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), including any amendments or reports filed for the purpose of updating such description.</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>All documents filed by the Registrant pursuant to Section 13(a), 13(c), 14 or 15(d) of the Exchange Act after the date hereof, and prior to the filing of a post-effective amendment which indicates that the securities offered hereby have been sold or which deregisters the securities covered hereby then remaining unsold, shall also be deemed to be incorporated by reference into this Registration Statement and to be a part hereof commencing on the respective dates on which such documents are filed.</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; margin-left:0.5in; text-indent:-0.5in;text-align:left;'><b><font size=2>Item 4.  DESCRIPTION OF SECURITIES</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>Not applicable.</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; margin-left:0.5in; text-indent:-0.5in;text-align:left;'><b><font size=2>Item 5.  INTERESTS OF NAMED EXPERTS AND COUNSEL</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>None.  </font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; margin-left:0.5in; text-indent:-0.5in;text-align:left;'><b><font size=2>Item 6.  INDEMNIFICATION OF DIRECTORS AND OFFICERS</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>We are an Oregon corporation. Section 60.047 of the Oregon Business Corporation Act authorizes a corporation to limit a director&#146;s liability to the corporation or its shareholders for monetary damages for conduct as a director, except in certain circumstances involving breach of the director&#146;s duty of loyalty, bad faith, intentional misconduct, knowing violations of law, illegal corporate distributions, or any transaction from which the director receives an improper personal benefit. Article VII of our articles of incorporation contains provisions implementing such limitations on a director&#146;s liability to the registrant and its shareholders to the fullest extent permitted by Oregon law. </font></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>Sections 60.391 through 60.414 of the Oregon Business Corporation Act authorize a court to award, or a corporation&#146;s board of directors to grant, indemnification to directors and officers on terms sufficiently broad to permit indemnification under certain circumstances for liabilities arising under the Securities Act of 1933, as amended. Article VIII of our articles of incorporation provides for indemnification of our directors, officers, employees and agents to the maximum extent not prohibited by Oregon law. </font></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt;text-align:left;'><font size=2>We may also indemnify our directors and officers against liability they may incur for serving in those capacities pursuant to a liability insurance policy we maintain for this purpose. In addition, we have contractually agreed to indemnify each of our directors for any liability they may incur by reason of the fact that they serve in that capacity, including liability under the Securities Act of 1933, as amended. </font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; margin-left:0.5in; text-indent:-0.5in;text-align:left;'><b><font size=2>Item 7.  EXEMPTION FROM REGISTRATION CLAIMED</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>Not applicable.</font></p>
  
  <!-- MARKER FORMAT-SHEET="Head Minor Center" FSL="Default" -->
  <P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>II-1 </FONT></P>
  
  
      <p style='page-break-before:always'></p>
      <pAGE>
  
  
      <p style=' margin-bottom:0pt; margin-top:12pt; margin-left:0.5in; text-indent:-0.5in;text-align:left;'><b><font size=2>Item 8.  EXHIBITS</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; text-indent:0.5in;text-align:left;'><font size=2>&nbsp;</font></p>
  
  
      <table border="0" cellspacing=0 cellpadding=0 width="77%" style='border-collapse:collapse'>
          <tr style='page-break-inside:avoid'>
              <td width="19%" valign=bottom style='padding:0in 5.4pt 0in 5.4pt'>
                  <div style='border-bottom:solid black 1.0pt;padding:0in 0in 1.0pt 0in'>
      <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:0pt;margin-bottom:0pt'><font size=2>Exhibit</font><br> <font size=2>Number</font></p> </div> </td>
              <td width="80%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <div style='border-bottom:solid black 1.0pt;padding:0in 0in 1.0pt 0in'>
      <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:0pt;margin-bottom:0pt'><br> <font size=2>Description</font></p> </div> </td> </tr>
          <tr style='page-break-inside:avoid'>
              <td width="19%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:6.0pt;margin-bottom:0pt'><font size=2>5.1</font></p> </td>
              <td width="80%" valign=bottom style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:6.0pt;margin-bottom:0pt'><font size=2>Opinion of Perkins Coie LLP regarding legality of the Common Stock being registered </font></p> </td> </tr>
          <tr style='page-break-inside:avoid'>
              <td width="19%" valign=bottom style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:6.0pt;margin-bottom:0pt'><font size=2>23.1</font></p> </td>
              <td width="80%" valign=bottom style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:left;margin-top:6.0pt;margin-bottom:0pt'><font size=2>Consent of  KPMG LLP (Independent Registered Public Accounting Firm) </font><font size=2> </font></p> </td> </tr>
          <tr style='page-break-inside:avoid'>
              <td width="19%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:6.0pt;margin-bottom:0pt'><font size=2>23.2</font></p> </td>
              <td width="80%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:6.0pt;margin-bottom:0pt'><font size=2>Consent of Perkins Coie LLP (included in opinion filed as Exhibit 5.1)</font></p> </td> </tr>
          <tr style='page-break-inside:avoid'>
              <td width="19%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:6.0pt;margin-bottom:0pt'><font size=2>24.1</font></p> </td>
              <td width="80%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:6.0pt;margin-bottom:0pt'><font size=2>Power of Attorney (see signature page)</font></p> </td> </tr>
          <tr style='page-break-inside:avoid'>
              <td width="19%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:6.0pt;margin-bottom:0pt'><font size=2>99.1</font></p> </td>
              <td width="80%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:6.0pt;margin-bottom:0pt'><font size=2>Synthetech, Inc. 2005 Equity Incentive Plan (1)</font></p> </td> </tr></table>
      <BR>
  
  <!-- MARKER FORMAT-SHEET="Para Hang" FSL="Default" -->
  <TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0>
  <TR VALIGN=TOP>
  <TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(1)  </FONT></TD>
  <TD><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp; </FONT></TD>
  <TD WIDTH=95%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Incorporated
  by reference to the Registrant's Definitive Proxy Statement for its Annual Meeting of
  Shareholders held on August 11, 2005 (filed on July 7, 2005).</FONT></TD>
  </TR>
  </TABLE>
  <BR>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; margin-left:0.5in; text-indent:-0.5in;text-align:left;'><b><font size=2>Item 9.  UNDERTAKINGS</font></b></p>
  
  
      <table border="0" cellspacing=0 cellpadding=0 width="317" style='border-collapse:collapse'>
          <tr >
              <td width="15%" valign=top style='padding:12.0pt 0in 0in 0in'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:left;margin-top:0in;margin-bottom:0pt'><font size=2>(a)</font></p> </td>
              <td width="84%" valign=top style='padding:12.0pt 0in 0in 0in'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:left;margin-top:0in;margin-bottom:0pt'><font size=2>The undersigned Registrant hereby undertakes:</font></p> </td> </tr></table>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>(1)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:</font></p>
  
  
      <table border="0" cellspacing=0 cellpadding=0 width="489" style='margin-left:1.0in;border-collapse:collapse'>
          <tr >
              <td width="12%" valign=top style='padding:12.0pt 0in 0in 0in'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:left;margin-top:0in;margin-bottom:0pt'><font size=2>(i)</font></p> </td>
              <td width="87%" valign=top style='padding:12.0pt 0in 0in 0in'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:left;margin-top:0in;margin-bottom:0pt'><font size=2>To include any prospectus required by Section 10(a)(3) of the Securities Act;</font></p> </td> </tr></table>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:1in;text-align:left;'><font size=2>(ii)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;To reflect in the prospectus any facts or events arising after the effective date of this Registration Statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in this Registration Statement; and</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:1in;text-align:left;'><font size=2>(iii)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;To include any material information with respect to the plan of distribution not previously disclosed in this Registration Statement or any material change to such information in this Registration Statement;  </font><u><font size=2>provided</font></u><font size=2>, </font><u><font size=2>however</font></u><font size=2>, that paragraphs (1)(i) and (1)(ii) above do not apply if the information required to be included in a post-effective amendment by those paragraphs is contained in periodic reports filed or furnished by the Registrant pursuant to Section&nbsp;13 or Section&nbsp;15(d) of the Exchange Act that are incorporated by reference in this Registration Statement.</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>(2)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>(3)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt;text-align:left;'><font size=2>(b)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the Registrant's annual report pursuant to Section 13(a) or 15(d) of the Exchange Act (and, where applicable, each filing of an employee benefit plan's annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in this Registration Statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>&nbsp;</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>&nbsp;</font></p>
  
  
  <!-- MARKER FORMAT-SHEET="Head Minor Center" FSL="Default" -->
  <P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>II-2 </FONT></P>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>&nbsp;</font></p>
  
      <p style='page-break-before:always'></p>
      <pAGE>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>&nbsp;</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt;text-align:left;'><font size=2>(c)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the Registrant pursuant to the foregoing provisions, or otherwise, the Registrant has been advised that in the opinion of the Securities and Exchange Commission such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable.  In the event that a claim for indemnification against such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered, the Registrant will, unless in the opinion of its
      counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt;text-align:left;'><font size=2>&nbsp;</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'>
  </p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>&nbsp;</font></p>
  
  
  <!-- MARKER FORMAT-SHEET="Head Minor Center" FSL="Default" -->
  <P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>II-3 </FONT></P>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>&nbsp;</font></p>
  
      <p style='page-break-before:always'></p>
      <pAGE>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>&nbsp;</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; margin-left:0in;text-align:center;'><b><font SIZE=2>SIGNATURES</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all the requirements for filing on Form&nbsp;S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Albany, State of Oregon, on September 23, 2005.</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>&nbsp;</font></p>
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>&nbsp;</font></p>
  
  
  <TABLE WIDTH="100%" CELLPADDING="0" CELLSPACING="0">
  <TR VALIGN="TOP">
       <TD WIDTH="50%"><FONT SIZE="2"></FONT></TD>
       <TD COLSPAN=2><FONT SIZE="2">Synthetech, Inc.</FONT></TD>
  </TR>
  <TR VALIGN="TOP">
       <TD WIDTH="50%"><FONT SIZE="2">&nbsp;<BR>&nbsp;</FONT></TD>
       <TD WIDTH="5%"><FONT SIZE="2">&nbsp;<BR>&nbsp;</FONT></TD>
       <TD WIDTH="45%"><FONT SIZE="2"></FONT></TD></TR>
  <TR VALIGN="TOP">
       <TD WIDTH="50%"><FONT SIZE="2"></FONT></TD>
       <TD><FONT SIZE="2"></FONT></TD>
       <TD><FONT SIZE="2">/s/ Gary A. Weber</FONT></TD></TR>
  <TR VALIGN="TOP">
       <TD WIDTH="50%"><FONT SIZE="2"></FONT></TD>
       <TD COLSPAN=2><FONT SIZE="2"></FONT><HR NOSHADE COLOR=BLACK SIZE=1></TD>
  </TR>
  <TR VALIGN="TOP">
       <TD WIDTH="50%"><FONT SIZE="2"></FONT></TD>
       <TD><FONT SIZE="2">By:</FONT></TD>
       <TD><FONT SIZE="2">Gary A. Weber</FONT></TD></TR>
  <TR VALIGN="TOP">
       <TD WIDTH="50%"><FONT SIZE="2"></FONT></TD>
       <TD><FONT SIZE="2"></FONT></TD>
       <TD><FONT SIZE="2">Vice President Finance and Administration, Chief Financial Officer, Secretary and Treasurer</FONT></TD></TR>
  </TABLE>
  
  
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:3.38in;text-align:left;'><font size=2>&nbsp;</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; margin-left:0.5in;text-align:center;'><b><font SIZE=2>POWER OF ATTORNEY</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>Each person whose signature appears below authorizes M. "Sreeni" Sreenivasan or Gary A. Weber, or either of them, as attorneys-in-fact with full power of substitution, to execute in the name and on the behalf of each person, individually and in each capacity stated below, and to file, any and all amendments to this Registration Statement, including any and all post-effective amendments.</font></p>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed by the following persons in the capacities indicated below on September 23, 2005.</font></p>
  
  
      <table border="0" cellspacing=0 cellpadding=0 width="95%" style='border-collapse:collapse'>
          <tr style='page-break-inside:avoid'>
              <td width="45%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:center;margin-top:12pt;margin-bottom:0pt'><u><b><font size=2>Signature</font></b></u><u></u></p> </td>
              <td width="54%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:center;margin-top:12pt;margin-bottom:0pt'><u><b><font size=2>Title</font></b></u><u></u></p> </td> </tr>
          <tr style='page-break-inside:avoid;height:9.0pt'>
              <td width="45%" valign=top style='padding:0in 5.4pt 0in 5.4pt; height:9.0pt'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:center;margin-top:12pt;margin-bottom:0pt'><font size=2>/s/ M. "Sreeni" Sreenivasan</font></p>
      <div style='border-top:solid black 1.0pt;padding:1.0pt 0in 0in 0in'>
      <p style='margin-left:0pt;text-indent:0in;text-align:center;margin-top:0in;margin-bottom:0pt'><font size=2>M. "Sreeni" Sreenivasan</font></p> </div> </td>
              <td width="54%" valign=top style='padding:0in 5.4pt 0in 5.4pt; height:9.0pt'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:left;margin-top:12pt;margin-bottom:0pt'><font size=2>President, Chief Executive Officer and Director (Principal Executive Officer)</font></p> </td> </tr>
          <tr style='page-break-inside:avoid;height:9.0pt'>
              <td width="45%" valign=top style='padding:0in 5.4pt 0in 5.4pt; height:9.0pt'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:center;margin-top:12pt;margin-bottom:0pt'><font size=2>/s/ Gary A. Weber</font></p>
      <div style='border-top:solid black 1.0pt;padding:1.0pt 0in 0in 0in'>
      <p style='margin-left:0pt;text-indent:0in;text-align:center;margin-top:0in;margin-bottom:0pt'><font size=2>Gary A. Weber</font></p> </div> </td>
              <td width="54%" valign=top style='padding:0in 5.4pt 0in 5.4pt; height:9.0pt'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:left;margin-top:12pt;margin-bottom:0pt'><font size=2>Vice President Finance and Administration, Chief Financial Officer, Secretary and Treasurer (Principal Financial Officer and Principal Accounting Officer)</font></p> </td> </tr>
          <tr style='page-break-inside:avoid;height:9.0pt'>
              <td width="45%" valign=top style='padding:0in 5.4pt 0in 5.4pt; height:9.0pt'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:center;margin-top:12pt;margin-bottom:0pt'><font size=2>/s/ Daniel T. Fagan</font></p>
      <div style='border-top:solid black 1.0pt;padding:1.0pt 0in 0in 0in'>
      <p style='margin-left:0pt;text-indent:0in;text-align:center;margin-top:0in;margin-bottom:0pt'><font size=2>Daniel T. Fagan</font></p> </div> </td>
              <td width="54%" valign=top style='padding:0in 5.4pt 0in 5.4pt; height:9.0pt'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:left;margin-top:12pt;margin-bottom:0pt'><font size=2>Chairman of the Board of Directors</font></p> </td> </tr>
          <tr style='page-break-inside:avoid;height:9.0pt'>
              <td width="45%" valign=top style='padding:0in 5.4pt 0in 5.4pt; height:9.0pt'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:center;margin-top:12pt;margin-bottom:0pt'><font size=2>/s/ Paul C. Ahrens</font></p>
      <div style='border-top:solid black 1.0pt;padding:1.0pt 0in 0in 0in'>
      <p style='margin-left:0pt;text-indent:0in;text-align:center;margin-top:0in;margin-bottom:0pt'><font size=2>Paul C. Ahrens</font></p> </div> </td>
              <td width="54%" valign=top style='padding:0in 5.4pt 0in 5.4pt; height:9.0pt'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:left;margin-top:12pt;margin-bottom:0pt'><font size=2>Director</font></p> </td> </tr>
          <tr style='page-break-inside:avoid;height:9.0pt'>
              <td width="45%" valign=top style='padding:0in 5.4pt 0in 5.4pt; height:9.0pt'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:center;margin-top:12pt;margin-bottom:0pt'><font size=2>/s/ Howard L. Farkas</font></p>
      <div style='border-top:solid black 1.0pt;padding:1.0pt 0in 0in 0in'>
      <p style='margin-left:0pt;text-indent:0in;text-align:center;margin-top:0in;margin-bottom:0pt'><font size=2>Howard L. Farkas</font></p> </div> </td>
              <td width="54%" valign=top style='padding:0in 5.4pt 0in 5.4pt; height:9.0pt'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:left;margin-top:12pt;margin-bottom:0pt'><font size=2>Director</font></p> </td> </tr>
          <tr style='page-break-inside:avoid;height:9.0pt'>
              <td width="45%" valign=top style='padding:0in 5.4pt 0in 5.4pt; height:9.0pt'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:center;margin-top:12pt;margin-bottom:0pt'><font size=2>/s/ Hans C. Noetzli</font></p>
      <div style='border-top:solid black 1.0pt;padding:1.0pt 0in 0in 0in'>
      <p style='margin-left:0pt;text-indent:0in;text-align:center;margin-top:0in;margin-bottom:0pt'><font size=2>Hans C. Noetzli</font></p> </div> </td>
              <td width="54%" valign=top style='padding:0in 5.4pt 0in 5.4pt; height:9.0pt'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:left;margin-top:12pt;margin-bottom:0pt'><font size=2>Director</font></p> </td> </tr>
          <tr style='page-break-inside:avoid; height:9.0pt'>
              <td width="45%" valign=top style='padding:0in 5.4pt 0in 5.4pt; height:9.0pt'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:center;margin-top:12pt;margin-bottom:0pt'><font size=2>/s/ Charles B. Williams</font></p>
      <div style='border-top:solid black 1.0pt;padding:1.0pt 0in 0in 0in'>
      <p style='margin-left:0pt;text-indent:0in;text-align:center;margin-top:0in;margin-bottom:0pt'><font size=2>Charles B. Williams</font></p> </div> </td>
              <td width="54%" valign=top style='padding:0in 5.4pt 0in 5.4pt; height:9.0pt'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:left;margin-top:12pt;margin-bottom:0pt'><font size=2>Director</font></p> </td> </tr></table>
  
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>&nbsp;</font></p>
  
  
  <!-- MARKER FORMAT-SHEET="Head Minor Center" FSL="Default" -->
  <P ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>II-4 </FONT></P>
  
      <p style=' margin-bottom:0pt; margin-top:12pt; text-indent:0.5in;text-align:left;'><font size=2>&nbsp;</font></p>
  
      <p style='page-break-before:always'></p>
      <pAGE>
  
  
      <p style=' margin-bottom:0pt; margin-top:12pt; margin-left:0.5in;text-align:center;'><b><font SIZE=2>INDEX TO EXHIBITS</font></b></p>
  
      <p style=' margin-bottom:0pt; margin-top:0pt; margin-left:0.5in;text-align:center;'><font size=2>&nbsp;</font></p>
  
  
      <table border="0" cellspacing=0 cellpadding=0 width="77%" style='border-collapse:collapse'>
          <tr style='page-break-inside:avoid'>
              <td width="19%" valign=bottom style='padding:0in 5.4pt 0in 5.4pt'>
                  <div style='border-bottom:solid black 1.0pt;padding:0in 0in 1.0pt 0in'>
      <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:0pt;margin-bottom:0pt'><font size=2>Exhibit</font><br> <font size=2>Number</font></p> </div> </td>
              <td width="80%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <div style='border-bottom:solid black 1.0pt;padding:0in 0in 1.0pt 0in'>
      <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:0pt;margin-bottom:0pt'><br> <font size=2>Description</font></p> </div> </td> </tr>
          <tr style='page-break-inside:avoid'>
              <td width="19%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:6.0pt;margin-bottom:0pt'><font size=2>5.1</font></p> </td>
              <td width="80%" valign=bottom style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:6.0pt;margin-bottom:0pt'><font size=2>Opinion of Perkins Coie LLP regarding legality of the Common Stock being registered </font></p> </td> </tr>
          <tr style='page-break-inside:avoid'>
              <td width="19%" valign=bottom style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:6.0pt;margin-bottom:0pt'><font size=2>23.1</font></p> </td>
              <td width="80%" valign=bottom style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0in;text-align:left;margin-top:6.0pt;margin-bottom:0pt'><font size=2>Consent of  KPMG LLP (Independent Registered Public Accounting Firm) </font><font size=2> </font></p> </td> </tr>
          <tr style='page-break-inside:avoid'>
              <td width="19%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:6.0pt;margin-bottom:0pt'><font size=2>23.2</font></p> </td>
              <td width="80%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:6.0pt;margin-bottom:0pt'><font size=2>Consent of Perkins Coie LLP (included in opinion filed as Exhibit 5.1)</font></p> </td> </tr>
          <tr style='page-break-inside:avoid'>
              <td width="19%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:6.0pt;margin-bottom:0pt'><font size=2>24.1</font></p> </td>
              <td width="80%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:6.0pt;margin-bottom:0pt'><font size=2>Power of Attorney (see signature page)</font></p> </td> </tr>
          <tr style='page-break-inside:avoid'>
              <td width="19%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:center;margin-top:6.0pt;margin-bottom:0pt'><font size=2>99.1</font></p> </td>
              <td width="80%" valign=top style='padding:0in 5.4pt 0in 5.4pt'>
                  <p style='margin-left:0pt;text-indent:0pt;text-align:left;margin-top:6.0pt;margin-bottom:0pt'><font size=2>Synthetech, Inc. 2005 Equity Incentive Plan (1)</font></p> </td> </tr></table>
      <BR>
  
  <!-- MARKER FORMAT-SHEET="Para Hang" FSL="Default" -->
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  <TR VALIGN=TOP>
  <TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(1)  </FONT></TD>
  <TD><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp; </FONT></TD>
  <TD WIDTH=95%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Incorporated
  by reference to the Registrant's Definitive Proxy Statement for its Annual Meeting of
  Shareholders held on August 11, 2005 (filed on July 7, 2005).</FONT></TD>
  </TR>
  </TABLE>
  
  
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metadata_filer: {"company-data": {"conformed-name": "SYNTHETECH INC", "cik": "0000749290", "assigned-sic": "2860", "irs-number": "840845771", "state-of-incorporation": "OR", "fiscal-year-end": "0331"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-128520", "film-number": "051100072"}, "business-address": {"street1": "1290 INDUSTRIAL WAY", "city": "ALBANY", "state": "OR", "zip": "97321", "phone": "5419676575"}, "mail-address": {"street1": "1290 INDUSTRIAL WAY", "city": "ALBANY", "state": "OR", "zip": "97321"}}
text: As filed with the Securities and Exchange Commission on September 23, 2005
  Registration No. 333-
  SECURITIES AND EXCHANGE COMMISSION
  Washington, D.C. 20549
  ______________________
  FORM S-8
  REGISTRATION STATEMENT
  UNDER
  THE SECURITIES ACT OF 1933
  ______________________
  SYNTHETECH,
  INC.
  (Exact name of Registrant as specified in its charter)
  Oregon
  84-0845771
  (State or other jurisdiction of incorporation or organization)
  (I.R.S. Employer Identification No.)
  1290 Industrial Way
  Albany Oregon 97322
  (541) 967-6575
  (Address of principal executive offices, including zip code)
  SYNTHETECH, INC. 2005 EQUITY INCENTIVE PLAN
  (Full title of the plan)
  Gary Weber
  1290 Industrial Way
  Albany, Oregon 97322
  (541) 967-6575
  (Name, address and telephone number, including area code, of agent for service)
  ______________________
  Copies to:
  David Matheson
  Perkins Coie LLP
  1120 NW Couch Street
  Portland, Oregon 97209
  (503) 727-2000
  ______________________
  CALCULATION OF REGISTRATION FEE
  Title of Securities
  to Be Registered
  Amount to Be
  Registered (1)
  Proposed Maximum
  Offering Price Per Share (2)
  Proposed Maximum
  Aggregate Offering Price
  Amount of Registration Fee
  Common Stock, no par value, (including, any associated common stock purchase rights) under the Synthetech, Inc. 2005 Equity Incentive Plan
  952,975
  $0.54
  $514,606.50
  $60.57
  (1)
  Includes
  an indeterminate number of additional shares that may be necessary to adjust the number
  of shares reserved for issuance pursuant to the plan as the result of any future stock
  split, stock dividend or similar adjustment of the Registrant's outstanding Common Stock.
  (2)
  Estimated
  solely for the purpose of calculating the registration fee pursuant to Rule 457(c)
  and Rule 457(h) under the Securities Act.  The proposed maximum offering price per share
  is estimated to be $0.54 based on the average of the high ($0.58) and low ($0.50) sales
  prices for the Common Stock on September 19, 2005 as reported for such date on the Nasdaq
  SmallCap Market.
  PART II
  INFORMATION REQUIRED IN REGISTRATION STATEMENT
  Item 3.  INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE
  The following documents filed with the Securities and Exchange Commission are hereby incorporated by reference in this Registration Statement:
  (a)            The Registrant's Annual Report for the year ended March 31, 2005 (filed on June 29, 2005), which contains audited financial statements for the most recent fiscal year for which such statements have been filed;
  (b)            The Registrant's Quarterly Report on Form 10-Q for the quarter ended June 30, 2005 (filed on August 4, 2005);
  (c)            The Registrant's Current Reports on Form 8-K, filed on May 26, 2005, August 26, 2005 and September 15, 2005; and
  (d)            The description of the Registrant's Common Stock contained in the Registrant's Registration Statement on Form 8-A filed on November 8, 1984 under Section 12(g) of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), including any amendments or reports filed for the purpose of updating such description.
  All documents filed by the Registrant pursuant to Section 13(a), 13(c), 14 or 15(d) of the Exchange Act after the date hereof, and prior to the filing of a post-effective amendment which indicates that the securities offered hereby have been sold or which deregisters the securities covered hereby then remaining unsold, shall also be deemed to be incorporated by reference into this Registration Statement and to be a part hereof commencing on the respective dates on which such documents are filed.
  Item 4.  DESCRIPTION OF SECURITIES
  Not applicable.
  Item 5.  INTERESTS OF NAMED EXPERTS AND COUNSEL
  None.
  Item 6.  INDEMNIFICATION OF DIRECTORS AND OFFICERS
  We are an Oregon corporation. Section 60.047 of the Oregon Business Corporation Act authorizes a corporation to limit a director's liability to the corporation or its shareholders for monetary damages for conduct as a director, except in certain circumstances involving breach of the director's duty of loyalty, bad faith, intentional misconduct, knowing violations of law, illegal corporate distributions, or any transaction from which the director receives an improper personal benefit. Article VII of our articles of incorporation contains provisions implementing such limitations on a director's liability to the registrant and its shareholders to the fullest extent permitted by Oregon law.
  Sections 60.391 through 60.414 of the Oregon Business Corporation Act authorize a court to award, or a corporation's board of directors to grant, indemnification to directors and officers on terms sufficiently broad to permit indemnification under certain circumstances for liabilities arising under the Securities Act of 1933, as amended. Article VIII of our articles of incorporation provides for indemnification of our directors, officers, employees and agents to the maximum extent not prohibited by Oregon law.
  We may also indemnify our directors and officers against liability they may incur for serving in those capacities pursuant to a liability insurance policy we maintain for this purpose. In addition, we have contractually agreed to indemnify each of our directors for any liability they may incur by reason of the fact that they serve in that capacity, including liability under the Securities Act of 1933, as amended.
  Item 7.  EXEMPTION FROM REGISTRATION CLAIMED
  Not applicable.
  II-1
  Item 8.  EXHIBITS
  Exhibit
  Number
  Description
  5.1
  Opinion of Perkins Coie LLP regarding legality of the Common Stock being registered
  23.1
  Consent of  KPMG LLP (Independent Registered Public Accounting Firm)
  23.2
  Consent of Perkins Coie LLP (included in opinion filed as Exhibit 5.1)
  24.1
  Power of Attorney (see signature page)
  99.1
  Synthetech, Inc. 2005 Equity Incentive Plan (1)
  (1)
  Incorporated
  by reference to the Registrant's Definitive Proxy Statement for its Annual Meeting of
  Shareholders held on August 11, 2005 (filed on July 7, 2005).
  Item 9.  UNDERTAKINGS
  (a)
  The undersigned Registrant hereby undertakes:
  (1)            To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:
  (i)
  To include any prospectus required by Section 10(a)(3) of the Securities Act;
  (ii)                To reflect in the prospectus any facts or events arising after the effective date of this Registration Statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in this Registration Statement; and
  (iii)               To include any material information with respect to the plan of distribution not previously disclosed in this Registration Statement or any material change to such information in this Registration Statement;
  provided
  ,
  however
  , that paragraphs (1)(i) and (1)(ii) above do not apply if the information required to be included in a post-effective amendment by those paragraphs is contained in periodic reports filed or furnished by the Registrant pursuant to Section 13 or Section 15(d) of the Exchange Act that are incorporated by reference in this Registration Statement.
  (2)            That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.
  (3)            To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.
  (b)            The undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the Registrant's annual report pursuant to Section 13(a) or 15(d) of the Exchange Act (and, where applicable, each filing of an employee benefit plan's annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in this Registration Statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.
  II-2
  (c)            Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the Registrant pursuant to the foregoing provisions, or otherwise, the Registrant has been advised that in the opinion of the Securities and Exchange Commission such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable.  In the event that a claim for indemnification against such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered, the Registrant will, unless in the opinion of its
      counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.
  II-3
  SIGNATURES
  Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Albany, State of Oregon, on September 23, 2005.
  Synthetech, Inc.
  /s/ Gary A. Weber
  By:
  Gary A. Weber
  Vice President Finance and Administration, Chief Financial Officer, Secretary and Treasurer
  POWER OF ATTORNEY
  Each person whose signature appears below authorizes M. "Sreeni" Sreenivasan or Gary A. Weber, or either of them, as attorneys-in-fact with full power of substitution, to execute in the name and on the behalf of each person, individually and in each capacity stated below, and to file, any and all amendments to this Registration Statement, including any and all post-effective amendments.
  Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed by the following persons in the capacities indicated below on September 23, 2005.
  Signature
  Title
  /s/ M. "Sreeni" Sreenivasan
  M. "Sreeni" Sreenivasan
  President, Chief Executive Officer and Director (Principal Executive Officer)
  /s/ Gary A. Weber
  Gary A. Weber
  Vice President Finance and Administration, Chief Financial Officer, Secretary and Treasurer (Principal Financial Officer and Principal Accounting Officer)
  /s/ Daniel T. Fagan
  Daniel T. Fagan
  Chairman of the Board of Directors
  /s/ Paul C. Ahrens
  Paul C. Ahrens
  Director
  /s/ Howard L. Farkas
  Howard L. Farkas
  Director
  /s/ Hans C. Noetzli
  Hans C. Noetzli
  Director
  /s/ Charles B. Williams
  Charles B. Williams
  Director
  II-4
  INDEX TO EXHIBITS
  Exhibit
  Number
  Description
  5.1
  Opinion of Perkins Coie LLP regarding legality of the Common Stock being registered
  23.1
  Consent of  KPMG LLP (Independent Registered Public Accounting Firm)
  23.2
  Consent of Perkins Coie LLP (included in opinion filed as Exhibit 5.1)
  24.1
  Power of Attorney (see signature page)
  99.1
  Synthetech, Inc. 2005 Equity Incentive Plan (1)
  (1)
  Incorporated
  by reference to the Registrant's Definitive Proxy Statement for its Annual Meeting of
  Shareholders held on August 11, 2005 (filed on July 7, 2005).