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  <P STYLE="margin: 0pt">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>As filed with the Securities and Exchange Commission
  on March 26, 2021</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>&nbsp;<BR></B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right"><B>Registration No. 333-______</B>&nbsp;</P>
  
  <!-- Field: Rule-Page --><DIV STYLE="margin-top: 1pt; margin-bottom: 1pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 3pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center">&nbsp;</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center">UNITED STATES</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center">SECURITIES AND
  EXCHANGE COMMISSION</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center">WASHINGTON, D.C.
  20549</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center">&nbsp;</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center">FORM S-8</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center">REGISTRATION STATEMENT</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center">UNDER</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center">THE SECURITIES
  ACT OF 1933</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 18pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>ADMA BIOLOGICS, INC.</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Exact name of registrant as specified in its charter)</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse; font-size: 10pt">
    <TR STYLE="vertical-align: top">
      <TD STYLE="width: 45%; border-bottom: Black 1pt solid; text-align: center"><FONT STYLE="font-size: 10pt"><B>Delaware</B></FONT></TD>
      <TD STYLE="width: 2%; text-align: justify">&nbsp;</TD>
      <TD STYLE="width: 45%; border-bottom: Black 1pt solid; text-align: center"><FONT STYLE="font-size: 10pt"><B>56-2590442</B></FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt">(State or other jurisdiction of</FONT></TD>
      <TD STYLE="text-align: left">&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt">(I.R.S. Employer Identification No.)</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt">incorporation or organization)</FONT></TD>
      <TD STYLE="text-align: left">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: left">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt"><B>465 State Route 17</B></FONT></TD>
      <TD STYLE="text-align: left">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
    <TR>
      <TD STYLE="vertical-align: top; border-bottom: Black 1pt solid; text-align: center"><FONT STYLE="font-size: 10pt"><B>Ramsey, New Jersey</B></FONT></TD>
      <TD STYLE="vertical-align: top; text-align: left">&nbsp;</TD>
      <TD STYLE="vertical-align: bottom; border-bottom: Black 1pt solid; text-align: center"><FONT STYLE="font-size: 10pt"><B>07446</B></FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt">(Address of Principal Executive Offices)</FONT></TD>
      <TD STYLE="text-align: left">&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt">(Zip Code)</FONT></TD></TR>
    </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>AMENDED AND RESTATED ADMA BIOLOGICS, INC. 2014
  OMNIBUS INCENTIVE COMPENSATION PLAN</B>&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Full title of the plan)</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse; font-size: 10pt">
    <TR STYLE="vertical-align: top">
      <TD STYLE="width: 45%; text-align: center"><FONT STYLE="font-size: 10pt"><B>Adam S. Grossman&nbsp;</B></FONT></TD>
      <TD STYLE="width: 2%; text-align: center">&nbsp;</TD>
      <TD STYLE="width: 45%; text-align: center">&nbsp;</TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt"><B>President and Chief Executive Officer</B></FONT></TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt"><B>David C. Schwartz, Esq.</B></FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt"><B>ADMA Biologics, Inc.</B></FONT></TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt"><B>Morgan, Lewis &amp; Bockius LLP</B></FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt"><B>465 State Route 17</B></FONT></TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt"><B>502 Carnegie Center</B></FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt"><B>Ramsey, New Jersey 07446</B></FONT></TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt"><B>Princeton, New Jersey 08540</B></FONT></TD></TR>
    <TR>
      <TD STYLE="vertical-align: top; border-bottom: Black 1pt solid; text-align: center"><FONT STYLE="font-size: 10pt"><B>(201) 478-5552</B></FONT></TD>
      <TD STYLE="vertical-align: top; text-align: center">&nbsp;</TD>
      <TD STYLE="vertical-align: bottom; border-bottom: Black 1pt solid; text-align: center"><FONT STYLE="font-size: 10pt"><B>&nbsp;(609) 919 6600</B></FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt">(Name, address, telephone number,</FONT></TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt">(With copies to)</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt">including area code, of agent for service)</FONT></TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
    </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in">Indicate by check mark whether
  the Registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging
  growth company. See the definitions of &ldquo;large accelerated filer,&rdquo; &ldquo;accelerated filer,&rdquo; &ldquo;smaller reporting
  company,&rdquo; and &ldquo;emerging growth company&rdquo; in Rule 12b-2 of the Exchange Act. (Check one):</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse; font-size: 10pt">
    <TR STYLE="vertical-align: top">
      <TD STYLE="width: 20%; padding-left: 0.1in; text-align: center; text-indent: -0.1in"><FONT STYLE="font-size: 10pt">Large accelerated filer&nbsp;<FONT STYLE="font-family: Wingdings">o</FONT></FONT></TD>
      <TD STYLE="width: 20%; text-align: center"><FONT STYLE="font-size: 10pt">Accelerated filer&nbsp;<FONT STYLE="font-family: Wingdings">o</FONT></FONT></TD>
      <TD STYLE="width: 20%">
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Non-accelerated filer&nbsp;<FONT STYLE="font-family: Wingdings">&yacute;</FONT></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Do not check if a smaller reporting company)</P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P></TD>
      <TD STYLE="width: 20%; text-align: center"><FONT STYLE="font-size: 10pt">Smaller reporting company&nbsp;<FONT STYLE="font-family: Wingdings">&yacute;</FONT></FONT></TD>
      <TD STYLE="width: 20%; text-align: center"><FONT STYLE="font-size: 10pt">Emerging growth company&nbsp;<FONT STYLE="font-family: Wingdings">o</FONT></FONT></TD></TR>
    </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in">If an emerging growth company,
  indicate by check mark if the Registrant has elected not to use the extended transition period for complying with any new or revised financial
  accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. &nbsp;<FONT STYLE="font-family: Wingdings">o</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in">&nbsp;</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center">CALCULATION OF
  REGISTRATION FEE</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse; font-size: 10pt">
    <TR STYLE="vertical-align: bottom">
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="width: 20%; text-align: justify">&nbsp;</TD>
      <TD STYLE="width: 20%; text-align: justify">&nbsp;</TD>
      <TD STYLE="width: 20%; text-align: justify">&nbsp;</TD>
      <TD STYLE="width: 20%; text-align: justify">&nbsp;</TD></TR>
    <TR STYLE="vertical-align: bottom">
      <TD STYLE="border-top: Black 2.5pt double; border-bottom: Black 1pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Title of securities<BR>
  to be registered</B></FONT></TD>
      <TD STYLE="border-top: Black 2.5pt double; border-bottom: Black 1pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Amount to be<BR>
  registered (1)</B></FONT></TD>
      <TD STYLE="border-top: Black 2.5pt double; border-bottom: Black 1pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Proposed<BR>
  maximum<BR>
  offering price<BR>
  per share (2)</B></FONT></TD>
      <TD STYLE="border-top: Black 2.5pt double; border-bottom: Black 1pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Proposed<BR>
  maximum<BR>
  aggregate offering<BR>
  price (2)</B></FONT></TD>
      <TD STYLE="border-top: Black 2.5pt double; border-bottom: Black 1pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Amount of<BR>
  registration fee</B></FONT></TD></TR>
    <TR>
      <TD STYLE="border-bottom: Black 2.5pt double; vertical-align: top; text-align: left"><FONT STYLE="font-size: 10pt">Common Stock, $0.0001 par value per share</FONT></TD>
      <TD STYLE="border-bottom: Black 2.5pt double; vertical-align: bottom; text-align: center"><FONT STYLE="font-size: 10pt">3,491,134</FONT></TD>
      <TD STYLE="border-bottom: Black 2.5pt double; vertical-align: bottom; text-align: center"><FONT STYLE="font-size: 10pt">$2.09</FONT></TD>
      <TD STYLE="border-bottom: Black 2.5pt double; vertical-align: bottom; text-align: center"><FONT STYLE="font-size: 10pt">$7,296,471</FONT></TD>
      <TD STYLE="border-bottom: Black 2.5pt double; vertical-align: bottom; text-align: center"><FONT STYLE="font-size: 10pt">$797</FONT></TD></TR>
    </TABLE>
  <TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
  <TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in">(1)</TD><TD STYLE="text-align: justify">3,491,134 shares of common stock, $0.0001 par value per share (&ldquo;Common Stock&rdquo;), of ADMA Biologics,
  Inc. (the &ldquo;Registrant&rdquo;) were automatically added to the shares authorized for issuance under the Amended and Restated ADMA
  Biologics, Inc. 2014 Omnibus Incentive Compensation Plan (the &ldquo;2014 Plan&rdquo;), on January 1, 2020 pursuant to an &ldquo;evergreen&rdquo;
  provision contained in the 2014 Plan. Pursuant to such provision, on January 1 of each year through 2022, the number of shares authorized
  for issuance under the 2014 Plan is automatically increased by a number equal to 4% of the outstanding shares of Common Stock as of the
  end of Registrant&rsquo;s immediately preceding fiscal year, or any lesser number of shares of Common Stock determined by the board of
  directors of the Registrant. In addition, pursuant to Rule 416(c) under the Securities Act of 1933, as amended (the &ldquo;Securities
  Act&rdquo;), this Registration Statement on Form S-8 also covers an indeterminate number of shares of Common Stock which may be offered
  or issued to prevent dilution resulting from adjustments as a result of stock dividends, stock splits, reverse stock splits, recapitalizations,
  reclassifications, mergers, split-ups, reorganizations, consolidations and other capital adjustments.</TD></TR></TABLE>
  
  <P STYLE="margin-top: 0pt; margin-bottom: 0pt; font: 10pt Times New Roman, Times, Serif">&nbsp;</P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
  <TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in">(2)</TD><TD STYLE="text-align: justify">Estimated solely for purposes of calculating the registration fee pursuant to Rule 457(c) and (h). The
  proposed maximum offering price per share, proposed maximum aggregate offering price and the amount of the registration fee are based
  on the average of the high and low prices of Registrant&rsquo;s Common Stock as reported on the Nasdaq Global Market on March 23, 2021.
  Pursuant to General Instruction E of Form S-8, the registration fee is calculated with respect to the additional securities registered
  on this Form S-8 only.</TD></TR></TABLE>
  
  <P STYLE="margin-top: 0pt; margin-bottom: 0pt; font: 10pt Times New Roman, Times, Serif">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"></P>
  
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>EXPLANATORY NOTE</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">This Registration Statement on Form S-8 (this
  &ldquo;Registration Statement&rdquo;) is being filed for the purpose of registering an additional 3,491,134 shares of common stock, $0.0001
  par value per share (the &ldquo;Common Stock&rdquo;), of ADMA Biologics, Inc. (the &ldquo;Registrant&rdquo;) that were added to the shares
  authorized for issuance under the Amended and Restated ADMA Biologics, Inc. 2014 Omnibus Incentive Compensation Plan (the &ldquo;2014
  Plan&rdquo;) pursuant to an &ldquo;evergreen&rdquo; provision contained in the 2014 Plan, for which Registration Statements on Form S-8
  relating to the same employee benefit plan are effective. Pursuant to the evergreen provision, on January 1 of each year through 2022,
  the number of shares authorized for issuance under the 2014 Plan is automatically increased by a number equal to 4% of the outstanding
  shares of Common Stock as of the end of Registrant&rsquo;s immediately preceding fiscal year, or any lesser number of shares of Common
  Stock determined by the board of directors of the Registrant.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">The Registrant previously filed the
  Registration Statements on Form S-8 (File Nos. 333-237658, 333-229921, 333-224492, 333-220058 and 333-204590) on April 13, 2020,
  February 27, 2019, April 27, 2018, August 18, 2017 and May 29, 2015, respectively, with the Securities and Exchange Commission (the
  &ldquo;Commission&rdquo;) to register an aggregate of 9,639,522 shares of Common Stock that were authorized for issuance under the
  2014 Plan (collectively, the &ldquo;Prior Registration Statements&rdquo;). Upon the effectiveness of this Registration Statement, an
  aggregate of 13,130,656 shares of Common Stock will be registered for issuance from time to time under the 2014 Plan. Pursuant to
  General Instruction E to Form S-8, the contents of the Prior Registration Statements are incorporated herein by reference except to
  the extent supplemented, amended or superseded by the information set forth herein. Only those items of Form S-8 containing new
  information not contained in the Prior Registration Statements are presented herein.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center">INCORPORATION BY
  REFERENCE</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">In accordance with General
  Instruction E to Form S-8, the contents of the Prior Registration Statements, with respect to securities offered pursuant to the 2014
  Plan, are hereby incorporated by reference.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">The following documents previously
  filed by the Registrant with the Commission are incorporated herein by reference and shall be deemed to be a part hereof:</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">(1)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The
  Registrant&rsquo;s Annual Report on Form 10-K for the year ended December 31, 2020, filed with the Commission on March 25, 2021;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">(2)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The
  Registrant&rsquo;s Current Reports on Form 8-K filed with the Commission on January 4, 2021, January 26, 2021, February 1, 2021, February
  3, 2021 and March 2, 2021 (provided that any portions of such reports that are deemed furnished and not filed pursuant to instructions
  to Form 8-K shall not be incorporated by reference into this Registration Statement); and</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">(3)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The
  description of Common Stock set forth in the Registrant&rsquo;s Registration Statement on Form 8-A12B filed with the Commission on November
  5, 2014 pursuant to Section 12(b) of the Securities Exchange Act of 1934, as amended (the &ldquo;Exchange Act&rdquo;), including any amendment
  or report filed for the purpose of updating such description.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">In addition, all documents
  that the Registrant files pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act subsequent to the effective date of this
  Registration Statement (except for any portions of the Registrant&rsquo;s Current Reports on Form 8-K furnished pursuant to Item 2.02
  or Item 7.01 thereof and any corresponding exhibits thereto not filed with the Commission), but prior to the filing of a post-effective
  amendment to this Registration Statement indicating that all securities offered hereby have been sold or which deregisters all securities
  then remaining unsold shall be deemed to be incorporated by reference in this Registration Statement and to be a part hereof from the
  date of filing such documents.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">For purposes of this Registration
  Statement, any document or statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed
  to be modified or superseded to the extent that a statement contained herein or in any other subsequently filed document which also is
  or is deemed to be incorporated by reference herein modifies or supersedes such document or statement in such document. Any such statement
  so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this Registration Statement.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"></P>
  
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center">EXHIBITS</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse; font-size: 10pt">
    <TR STYLE="vertical-align: bottom">
      <TD STYLE="width: 11%; padding-left: 0.1in; text-align: left; text-indent: -0.1in"><FONT STYLE="font-size: 10pt"><B>EXHIBIT</B></FONT></TD>
      <TD STYLE="width: 2%; text-align: left">&nbsp;</TD>
      <TD STYLE="width: 87%; text-align: left">&nbsp;</TD></TR>
    <TR STYLE="vertical-align: bottom">
      <TD STYLE="border-bottom: Black 1pt solid; padding-left: 0.1in; text-align: left; text-indent: -0.1in"><FONT STYLE="font-size: 10pt"><B>NUMBER</B></FONT></TD>
      <TD STYLE="text-align: left">&nbsp;</TD>
      <TD STYLE="border-bottom: Black 1pt solid; text-align: left"><FONT STYLE="font-size: 10pt"><B>DESCRIPTION</B></FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding-left: 0.1in; text-align: justify; text-indent: -0.1in">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding-left: 0.1in; text-align: justify; text-indent: -0.1in"><FONT STYLE="font-size: 10pt">4.1</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><A HREF="https://www.sec.gov/Archives/edgar/data/1368514/000119380520001546/e620138_ex4-1.htm">Rights Agreement, dated as of December 16, 2020, by and between ADMA Biologics, Inc. and Continental Stock Transfer and Trust Company, as rights agent (incorporated by reference to Exhibit 4.1 to the Company&rsquo;s Current Report on Form 8-K filed with the SEC on December 16, 2020).</A></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding-left: 0.1in; text-align: justify; text-indent: -0.1in"><FONT STYLE="font-size: 10pt">5.1</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><A HREF="e620410_ex5-1.htm" STYLE="-sec-extract: exhibit">Opinion of Morgan, Lewis and Bockius LLP, counsel for the Registrant, regarding the legal validity of the shares of Common Stock being registered on this Registration Statement (filed herewith).</A></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding-left: 0.1in; text-align: justify; text-indent: -0.1in"><FONT STYLE="font-size: 10pt">10.1</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1368514/000119380517001506/e616485_ex10-1.htm">Amended and Restated ADMA Biologics, Inc. 2014 Omnibus Incentive Compensation Plan (incorporated herein by reference to Exhibit 10.1 to the Registrant&rsquo;s Registration Statement on Form S-8 filed on August 18, 2017).</A></FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding-left: 0.1in; text-align: justify; text-indent: -0.1in">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding-left: 0.1in; text-align: justify; text-indent: -0.1in"><FONT STYLE="font-size: 10pt">23.1</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt"><A HREF="e620410_ex5-1.htm" STYLE="-sec-extract: exhibit">Consent of Morgan, Lewis and Bockius LLP (contained in Exhibit 5.1).</A></FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding-left: 0.1in; text-align: justify; text-indent: -0.1in">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding-left: 0.1in; text-align: justify; text-indent: -0.1in"><FONT STYLE="font-size: 10pt">23.2</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><A HREF="e620410_ex23-2.htm" STYLE="-sec-extract: exhibit">Consent of CohnReznick LLP, the Registrant&rsquo;s Independent Registered Public Accounting Firm (filed herewith).</A></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding-left: 0.1in; text-align: justify; text-indent: -0.1in"><FONT STYLE="font-size: 10pt">24.1</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><A HREF="#poa">Power of Attorney (included on signature page).</A></P></TD></TR>
    </TABLE>
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center">&nbsp;</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center"></P>
  
  <!-- Field: Page; Sequence: 3 -->
      <DIV STYLE="margin-top: 6pt; margin-bottom: 6pt; border-bottom: Black 2px solid"><P STYLE="margin-top: 0pt; text-align: center; margin-bottom: 0pt">&nbsp;</P></DIV>
      <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin-top: 0pt; margin-bottom: 0pt; text-align: center; font-size: 8pt">&nbsp;</P></DIV>
      <!-- Field: /Page -->
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center">&nbsp;</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center">SIGNATURES</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">Pursuant to the requirements
  of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the
  requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto
  duly authorized, in the City of Ramsey, State of New Jersey, on this 26<SUP>th</SUP> day of March, 2021.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse; font-size: 10pt">
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD COLSPAN="2">
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>ADMA Biologics, Inc.</B></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">(Registrant)</P></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD COLSPAN="2" STYLE="text-align: justify">&nbsp;</TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="width: 51%; text-align: left"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="width: 3%; text-align: left"><FONT STYLE="font-size: 10pt">By:</FONT></TD>
      <TD STYLE="width: 35%; border-bottom: Black 1pt solid; text-align: left"><FONT STYLE="font-size: 10pt">/s/ Brian Lenz</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: left">&nbsp;</TD>
      <TD STYLE="text-align: left">&nbsp;</TD>
      <TD STYLE="text-align: left"><FONT STYLE="font-size: 10pt">Name: Brian Lenz </FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: left"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-align: left"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="text-align: left"><FONT STYLE="font-size: 10pt">Title: Executive Vice President and Chief Financial Officer</FONT></TD></TR>
    </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"></P>
  
  <!-- Field: Page; Sequence: 4 -->
      <DIV STYLE="margin-top: 6pt; margin-bottom: 6pt; border-bottom: Black 2px solid"><P STYLE="margin-top: 0pt; text-align: center; margin-bottom: 0pt">&nbsp;</P></DIV>
      <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin-top: 0pt; margin-bottom: 0pt; text-align: center; font-size: 8pt">&nbsp;</P></DIV>
      <!-- Field: /Page -->
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><A NAME="poa"></A>KNOW BY ALL PERSONS BY THESE
  PRESENTS, that each person whose signature appears below constitutes and appoints Adam S. Grossman and Brian Lenz, and each of them, the
  undersigned&rsquo;s true and lawful attorneys-in-fact and agents, with full power of substitution and revocation, for and in the undersigned&rsquo;s
  name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective amendments) to this Registration
  Statement on Form S-8 (this &ldquo;Registration Statement&rdquo;) and any registration statement filed pursuant to Rule 462(b) under the
  Securities Act of 1933, as amended (the &ldquo;Securities Act&rdquo;), and to file the same, with all exhibits thereto, and other documents
  in connection therewith, with the Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority
  to do and perform each and every act and thing requisite and necessary to be done, as fully to all intents and purposes as the undersigned
  might or could do in person, hereby ratify and confirming all that said attorneys-in-fact and agents or any of them, or their or his substitutes,
  may lawfully do or cause to be done by virtue thereof.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">Pursuant to the requirements
  of the Securities Act, this Registration Statement has been signed below by the following persons on behalf of the Registrant and in the
  capacities indicated on the date listed below.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font-size: 10pt">
    <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: Black 2pt solid; width: 30%; text-align: justify"><FONT STYLE="font-size: 10pt"><B>Signature</B></FONT></TD>
      <TD STYLE="border-bottom: Black 2pt solid; width: 2%; text-align: center">&nbsp;</TD>
      <TD STYLE="border-bottom: Black 2pt solid; text-align: center"><FONT STYLE="font-size: 10pt"><B>Capacity</B></FONT></TD>
      <TD STYLE="border-bottom: Black 2pt solid; width: 2%; text-align: center">&nbsp;</TD>
      <TD STYLE="border-bottom: Black 2pt solid; width: 20%; text-align: center"><FONT STYLE="font-size: 10pt"><B>Date</B></FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD></TR>
    <TR>
      <TD STYLE="border-bottom: Black 1pt solid; vertical-align: bottom; text-align: left"><FONT STYLE="font-size: 10pt">/s/ Adam S. Grossman</FONT></TD>
      <TD STYLE="vertical-align: top; text-align: justify">&nbsp;</TD>
      <TD STYLE="vertical-align: top; text-align: left"><FONT STYLE="font-size: 10pt">President and Chief Executive Officer, Director</FONT></TD>
      <TD STYLE="vertical-align: top; text-align: justify">&nbsp;</TD>
      <TD STYLE="vertical-align: top; text-align: justify"><FONT STYLE="font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;March 26, 2021</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt">&nbsp;&nbsp;Adam S. Grossman</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: left"><FONT STYLE="font-size: 10pt">(Principal Executive Officer)</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD></TR>
    <TR>
      <TD STYLE="border-bottom: Black 1pt solid; vertical-align: bottom; text-align: left"><FONT STYLE="font-size: 10pt">/s/ Brian Lenz</FONT></TD>
      <TD STYLE="vertical-align: top; text-align: justify">&nbsp;</TD>
      <TD STYLE="vertical-align: top; text-align: left"><FONT STYLE="font-size: 10pt">Executive Vice President and Chief Financial Officer</FONT></TD>
      <TD STYLE="vertical-align: top; text-align: justify">&nbsp;</TD>
      <TD STYLE="vertical-align: top; text-align: justify"><FONT STYLE="font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;March 26, 2021</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt">&nbsp;&nbsp;Brian Lenz</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: left"><FONT STYLE="font-size: 10pt">(Principal Financial Officer and Principal Accounting Officer)</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD></TR>
    <TR>
      <TD STYLE="border-bottom: Black 1pt solid; vertical-align: bottom; text-align: left"><FONT STYLE="font-size: 10pt">/s/ Steven A. Elms</FONT></TD>
      <TD STYLE="vertical-align: top; text-align: justify">&nbsp;</TD>
      <TD STYLE="vertical-align: top; text-align: left"><FONT STYLE="font-size: 10pt">Chairman of the Board of Directors&nbsp; </FONT></TD>
      <TD STYLE="vertical-align: top; text-align: justify">&nbsp;</TD>
      <TD STYLE="vertical-align: top; text-align: justify"><FONT STYLE="font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;March 26, 2021</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt">&nbsp;&nbsp;Steven A. Elms</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: left">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD></TR>
    <TR>
      <TD STYLE="border-bottom: Black 1pt solid; vertical-align: bottom; text-align: left"><FONT STYLE="font-size: 10pt">/s/ Dr. Jerrold B. Grossman</FONT></TD>
      <TD STYLE="vertical-align: top; text-align: justify">&nbsp;</TD>
      <TD STYLE="vertical-align: top; text-align: left"><FONT STYLE="font-size: 10pt">Vice Chairman of the Board of Directors</FONT></TD>
      <TD STYLE="vertical-align: top; text-align: justify">&nbsp;</TD>
      <TD STYLE="vertical-align: top; text-align: justify"><FONT STYLE="font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;March 26, 2021</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt">&nbsp;&nbsp;Dr. Jerrold B. Grossman</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: Black 1pt solid; text-align: left"><FONT STYLE="font-size: 10pt">/s/ Martha J. Demski</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt">Director</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;March 26, 2021</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt">&nbsp;&nbsp;Martha J. Demski</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: Black 1pt solid; text-align: left"><FONT STYLE="font-size: 10pt">/s/ Bryant E. Fong</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt">Director</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;March 26, 2021</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt">&nbsp;&nbsp;Bryant E. Fong</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: Black 1pt solid; text-align: left"><FONT STYLE="font-size: 10pt">/s/ Lawrence P. Guiheen</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt">Director</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;March 26, 2021</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt">&nbsp;&nbsp;Lawrence P. Guiheen</FONT></TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD>
      <TD STYLE="text-align: justify">&nbsp;</TD></TR>
    </TABLE>
  
  <P STYLE="margin-top: 0; margin-bottom: 0">&nbsp;</P>
  
  <P STYLE="margin-top: 0; margin-bottom: 0">&nbsp;</P>
  
  <P STYLE="margin-top: 0; margin-bottom: 0">&nbsp;</P>
  
  </BODY>
  </HTML>
metadata_documents: [{"type": "S-8", "sequence": "1", "filename": "e620410_s8-adma.htm", "secsgml_size_bytes": 44534}]
metadata_filer: {"company-data": {"conformed-name": "ADMA BIOLOGICS, INC.", "cik": "0001368514", "assigned-sic": "2836", "irs-number": "562590442", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-254770", "film-number": "21777682"}, "business-address": {"street1": "C/O ADMA BIOLOGICS, INC.", "street2": "465 STATE ROUTE 17", "city": "RAMSEY", "state": "NJ", "zip": "07446", "phone": "(201) 478-5552"}, "mail-address": {"street1": "C/O ADMA BIOLOGICS, INC.", "street2": "465 STATE ROUTE 17", "city": "RAMSEY", "state": "NJ", "zip": "07446"}, "former-company": {"former-conformed-name": "R&R ACQUISITION VI, INC", "date-changed": "20060707"}}
text: As filed with the Securities and Exchange Commission
  on March 26, 2021
  Registration No. 333-______
  UNITED STATES
  SECURITIES AND
  EXCHANGE COMMISSION
  WASHINGTON, D.C.
  20549
  FORM S-8
  REGISTRATION STATEMENT
  UNDER
  THE SECURITIES
  ACT OF 1933
  ADMA BIOLOGICS, INC.
  (Exact name of registrant as specified in its charter)
  Delaware
  56-2590442
  (State or other jurisdiction of
  (I.R.S. Employer Identification No.)
  incorporation or organization)
  465 State Route 17
  Ramsey, New Jersey
  07446
  (Address of Principal Executive Offices)
  (Zip Code)
  AMENDED AND RESTATED ADMA BIOLOGICS, INC. 2014
  OMNIBUS INCENTIVE COMPENSATION PLAN
  (Full title of the plan)
  Adam S. Grossman
  President and Chief Executive Officer
  David C. Schwartz, Esq.
  ADMA Biologics, Inc.
  Morgan, Lewis & Bockius LLP
  465 State Route 17
  502 Carnegie Center
  Ramsey, New Jersey 07446
  Princeton, New Jersey 08540
  (201) 478-5552
  (609) 919 6600
  (Name, address, telephone number,
  (With copies to)
  including area code, of agent for service)
  Indicate by check mark whether
  the Registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging
  growth company. See the definitions of "large accelerated filer," "accelerated filer," "smaller reporting
  company," and "emerging growth company" in Rule 12b-2 of the Exchange Act. (Check one):
  Large accelerated filer
  o
  Accelerated filer
  o
  Non-accelerated filer
  ý
  (Do not check if a smaller reporting company)
  Smaller reporting company
  ý
  Emerging growth company
  o
  If an emerging growth company,
  indicate by check mark if the Registrant has elected not to use the extended transition period for complying with any new or revised financial
  accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act.
  o
  CALCULATION OF
  REGISTRATION FEE
  Title of securities
  to be registered
  Amount to be
  registered (1)
  Proposed
  maximum
  offering price
  per share (2)
  Proposed
  maximum
  aggregate offering
  price (2)
  Amount of
  registration fee
  Common Stock, $0.0001 par value per share
  3,491,134
  $2.09
  $7,296,471
  $797
  (1)
  3,491,134 shares of common stock, $0.0001 par value per share ("Common Stock"), of ADMA Biologics,
  Inc. (the "Registrant") were automatically added to the shares authorized for issuance under the Amended and Restated ADMA
  Biologics, Inc. 2014 Omnibus Incentive Compensation Plan (the "2014 Plan"), on January 1, 2020 pursuant to an "evergreen"
  provision contained in the 2014 Plan. Pursuant to such provision, on January 1 of each year through 2022, the number of shares authorized
  for issuance under the 2014 Plan is automatically increased by a number equal to 4% of the outstanding shares of Common Stock as of the
  end of Registrant's immediately preceding fiscal year, or any lesser number of shares of Common Stock determined by the board of
  directors of the Registrant. In addition, pursuant to Rule 416(c) under the Securities Act of 1933, as amended (the "Securities
  Act"), this Registration Statement on Form S-8 also covers an indeterminate number of shares of Common Stock which may be offered
  or issued to prevent dilution resulting from adjustments as a result of stock dividends, stock splits, reverse stock splits, recapitalizations,
  reclassifications, mergers, split-ups, reorganizations, consolidations and other capital adjustments.
  (2)
  Estimated solely for purposes of calculating the registration fee pursuant to Rule 457(c) and (h). The
  proposed maximum offering price per share, proposed maximum aggregate offering price and the amount of the registration fee are based
  on the average of the high and low prices of Registrant's Common Stock as reported on the Nasdaq Global Market on March 23, 2021.
  Pursuant to General Instruction E of Form S-8, the registration fee is calculated with respect to the additional securities registered
  on this Form S-8 only.
  EXPLANATORY NOTE
  This Registration Statement on Form S-8 (this
  "Registration Statement") is being filed for the purpose of registering an additional 3,491,134 shares of common stock, $0.0001
  par value per share (the "Common Stock"), of ADMA Biologics, Inc. (the "Registrant") that were added to the shares
  authorized for issuance under the Amended and Restated ADMA Biologics, Inc. 2014 Omnibus Incentive Compensation Plan (the "2014
  Plan") pursuant to an "evergreen" provision contained in the 2014 Plan, for which Registration Statements on Form S-8
  relating to the same employee benefit plan are effective. Pursuant to the evergreen provision, on January 1 of each year through 2022,
  the number of shares authorized for issuance under the 2014 Plan is automatically increased by a number equal to 4% of the outstanding
  shares of Common Stock as of the end of Registrant's immediately preceding fiscal year, or any lesser number of shares of Common
  Stock determined by the board of directors of the Registrant.
  The Registrant previously filed the
  Registration Statements on Form S-8 (File Nos. 333-237658, 333-229921, 333-224492, 333-220058 and 333-204590) on April 13, 2020,
  February 27, 2019, April 27, 2018, August 18, 2017 and May 29, 2015, respectively, with the Securities and Exchange Commission (the
  "Commission") to register an aggregate of 9,639,522 shares of Common Stock that were authorized for issuance under the
  2014 Plan (collectively, the "Prior Registration Statements"). Upon the effectiveness of this Registration Statement, an
  aggregate of 13,130,656 shares of Common Stock will be registered for issuance from time to time under the 2014 Plan. Pursuant to
  General Instruction E to Form S-8, the contents of the Prior Registration Statements are incorporated herein by reference except to
  the extent supplemented, amended or superseded by the information set forth herein. Only those items of Form S-8 containing new
  information not contained in the Prior Registration Statements are presented herein.
  INCORPORATION BY
  REFERENCE
  In accordance with General
  Instruction E to Form S-8, the contents of the Prior Registration Statements, with respect to securities offered pursuant to the 2014
  Plan, are hereby incorporated by reference.
  The following documents previously
  filed by the Registrant with the Commission are incorporated herein by reference and shall be deemed to be a part hereof:
  (1)       The
  Registrant's Annual Report on Form 10-K for the year ended December 31, 2020, filed with the Commission on March 25, 2021;
  (2)       The
  Registrant's Current Reports on Form 8-K filed with the Commission on January 4, 2021, January 26, 2021, February 1, 2021, February
  3, 2021 and March 2, 2021 (provided that any portions of such reports that are deemed furnished and not filed pursuant to instructions
  to Form 8-K shall not be incorporated by reference into this Registration Statement); and
  (3)       The
  description of Common Stock set forth in the Registrant's Registration Statement on Form 8-A12B filed with the Commission on November
  5, 2014 pursuant to Section 12(b) of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), including any amendment
  or report filed for the purpose of updating such description.
  In addition, all documents
  that the Registrant files pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act subsequent to the effective date of this
  Registration Statement (except for any portions of the Registrant's Current Reports on Form 8-K furnished pursuant to Item 2.02
  or Item 7.01 thereof and any corresponding exhibits thereto not filed with the Commission), but prior to the filing of a post-effective
  amendment to this Registration Statement indicating that all securities offered hereby have been sold or which deregisters all securities
  then remaining unsold shall be deemed to be incorporated by reference in this Registration Statement and to be a part hereof from the
  date of filing such documents.
  For purposes of this Registration
  Statement, any document or statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed
  to be modified or superseded to the extent that a statement contained herein or in any other subsequently filed document which also is
  or is deemed to be incorporated by reference herein modifies or supersedes such document or statement in such document. Any such statement
  so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this Registration Statement.
  EXHIBITS
  EXHIBIT
  NUMBER
  DESCRIPTION
  4.1
  Rights Agreement, dated as of December 16, 2020, by and between ADMA Biologics, Inc. and Continental Stock Transfer and Trust Company, as rights agent (incorporated by reference to Exhibit 4.1 to the Company's Current Report on Form 8-K filed with the SEC on December 16, 2020).
  5.1
  Opinion of Morgan, Lewis and Bockius LLP, counsel for the Registrant, regarding the legal validity of the shares of Common Stock being registered on this Registration Statement (filed herewith).
  10.1
  Amended and Restated ADMA Biologics, Inc. 2014 Omnibus Incentive Compensation Plan (incorporated herein by reference to Exhibit 10.1 to the Registrant's Registration Statement on Form S-8 filed on August 18, 2017).
  23.1
  Consent of Morgan, Lewis and Bockius LLP (contained in Exhibit 5.1).
  23.2
  Consent of CohnReznick LLP, the Registrant's Independent Registered Public Accounting Firm (filed herewith).
  24.1
  Power of Attorney (included on signature page).
  SIGNATURES
  Pursuant to the requirements
  of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the
  requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto
  duly authorized, in the City of Ramsey, State of New Jersey, on this 26
  th
  day of March, 2021.
  ADMA Biologics, Inc.
  (Registrant)
  By:
  /s/ Brian Lenz
  Name: Brian Lenz
  Title: Executive Vice President and Chief Financial Officer
  KNOW BY ALL PERSONS BY THESE
  PRESENTS, that each person whose signature appears below constitutes and appoints Adam S. Grossman and Brian Lenz, and each of them, the
  undersigned's true and lawful attorneys-in-fact and agents, with full power of substitution and revocation, for and in the undersigned's
  name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective amendments) to this Registration
  Statement on Form S-8 (this "Registration Statement") and any registration statement filed pursuant to Rule 462(b) under the
  Securities Act of 1933, as amended (the "Securities Act"), and to file the same, with all exhibits thereto, and other documents
  in connection therewith, with the Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority
  to do and perform each and every act and thing requisite and necessary to be done, as fully to all intents and purposes as the undersigned
  might or could do in person, hereby ratify and confirming all that said attorneys-in-fact and agents or any of them, or their or his substitutes,
  may lawfully do or cause to be done by virtue thereof.
  Pursuant to the requirements
  of the Securities Act, this Registration Statement has been signed below by the following persons on behalf of the Registrant and in the
  capacities indicated on the date listed below.
  Signature
  Capacity
  Date
  /s/ Adam S. Grossman
  President and Chief Executive Officer, Director
  March 26, 2021
  Adam S. Grossman
  (Principal Executive Officer)
  /s/ Brian Lenz
  Executive Vice President and Chief Financial Officer
  March 26, 2021
  Brian Lenz
  (Principal Financial Officer and Principal Accounting Officer)
  /s/ Steven A. Elms
  Chairman of the Board of Directors
  March 26, 2021
  Steven A. Elms
  /s/ Dr. Jerrold B. Grossman
  Vice Chairman of the Board of Directors
  March 26, 2021
  Dr. Jerrold B. Grossman
  /s/ Martha J. Demski
  Director
  March 26, 2021
  Martha J. Demski
  /s/ Bryant E. Fong
  Director
  March 26, 2021
  Bryant E. Fong
  /s/ Lawrence P. Guiheen
  Director
  March 26, 2021
  Lawrence P. Guiheen