content: <HTML>
  <HEAD>
       <TITLE></TITLE>
  </HEAD>
  <BODY STYLE="font: 10pt Times New Roman, Times, Serif">
  
  <P STYLE="margin: 0"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.4pt 0 0"></P>
  
  <!-- Field: Rule-Page --><DIV STYLE="margin-top: 0; margin-bottom: 0; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid; border-bottom: Black 1pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.4pt 0 0"></P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 4.95pt 5.5pt 0 5.45pt; text-align: center">As filed with the Securities
  and Exchange Commission on December 17, 2019</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.35pt 0 0"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.05pt 5.75pt 0 0; text-align: right"><B>Registration Statement No.
  333-</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 4.95pt">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 5.45pt; text-align: center"><B>UNITED STATES</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 1.1pt 5.45pt 0; text-align: center"><B>SECURITIES AND EXCHANGE COMMISSION</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 1.05pt 5.45pt 0; text-align: center"><B>Washington, D.C. 20549</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.15pt 0 0"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 5.45pt; text-align: center"><B>FORM S-8</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 1.35pt 5.45pt 0; text-align: center"><B>REGISTRATION STATEMENT UNDER
  THE SECURITIES ACT OF 1933</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.2pt 5.5pt 0 5.45pt; text-align: center">_____________________</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.3pt 0 0">&nbsp;</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 5.45pt; text-align: center">CORMEDIX INC.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 1.35pt 5.45pt 0; text-align: center"><B>(Exact name of registrant
  as specified in its charter)</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 1.35pt 5.45pt 0; text-align: center"><B>&nbsp;</B></P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 98.98%; border-collapse: collapse">
  <TR>
      <TD STYLE="vertical-align: top; width: 46.56%; border-bottom: black 1.5pt solid; padding-top: 0.05pt; padding-right: 5.45pt; padding-left: 5.45pt; font-weight: bold; text-align: center; font-size: 10pt">Delaware</TD>
      <TD STYLE="vertical-align: bottom; width: 3.46%; padding-top: 0.05pt; padding-right: 5.45pt; padding-left: 5.45pt; font-weight: bold; text-align: center; font-size: 10pt">&nbsp;</TD>
      <TD STYLE="vertical-align: bottom; width: 3.46%; padding-top: 0.05pt; padding-right: 5.45pt; padding-left: 5.45pt; font-weight: bold; text-align: center; font-size: 10pt">&nbsp;</TD>
      <TD STYLE="vertical-align: top; width: 46.54%; border-bottom: black 1.5pt solid; padding-top: 0.05pt; padding-right: 5.45pt; padding-left: 5.45pt; font-weight: bold; text-align: center; font-size: 10pt">20-5894890</TD></TR>
  <TR>
      <TD STYLE="vertical-align: top">
          <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0.05pt 5.45pt 0; text-align: center">(State of other jurisdiction
          of</P>
          <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0.05pt 5.45pt 0; text-align: center">incorporation or organization)</P></TD>
      <TD STYLE="vertical-align: bottom; padding-top: 0.05pt; padding-right: 5.45pt; padding-left: 5.45pt; font-weight: bold; text-align: center; font-size: 10pt">&nbsp;</TD>
      <TD STYLE="vertical-align: bottom; padding-top: 0.05pt; padding-right: 5.45pt; padding-left: 5.45pt; font-weight: bold; text-align: center; font-size: 10pt">&nbsp;</TD>
      <TD STYLE="vertical-align: top">
          <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0.05pt 5.45pt 0; text-align: center">(I.R.S. Employer</P>
          <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0.05pt 5.45pt 0; text-align: center">Identification No.)</P></TD></TR>
  </TABLE>
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0.05pt 5.45pt 0; text-align: center">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR>
      <TD STYLE="vertical-align: top; width: 50%; border-bottom: black 1.5pt solid; padding-right: 3pt; padding-left: 3pt">
          <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0.05pt 5.45pt 0; text-align: center">400 Connell Drive, Suite
          5000</P>
          <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0.05pt 5.45pt 0; text-align: center">Berkeley Heights, NJ</P></TD>
      <TD STYLE="vertical-align: bottom; width: 1%; padding-top: 0.05pt; padding-right: 5.45pt; padding-left: 5.45pt; font-weight: bold; text-align: center">&nbsp;</TD>
      <TD STYLE="vertical-align: bottom; width: 49%; border-bottom: black 1.5pt solid; padding-top: 0.05pt; padding-right: 5.45pt; padding-left: 5.45pt; font-weight: bold; text-align: center">07922</TD></TR>
  <TR>
      <TD STYLE="vertical-align: top; padding-top: 0.05pt; padding-right: 5.45pt; padding-left: 5.45pt; font-weight: bold; text-align: center">(Address of principal executive offices)</TD>
      <TD STYLE="vertical-align: bottom; padding-top: 0.05pt; padding-right: 5.45pt; padding-left: 5.45pt; font-weight: bold; text-align: center">&nbsp;</TD>
      <TD STYLE="vertical-align: top; padding-top: 0.05pt; padding-right: 5.45pt; padding-left: 5.45pt; font-weight: bold; text-align: center">(Zip Code)</TD></TR>
  </TABLE>
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0.05pt 5.45pt 0; text-align: center">&nbsp;&nbsp;</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0.05pt 5.45pt 0; text-align: center">CorMedix Inc. 2019 Omnibus
  Stock Incentive Plan</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.15pt 3.55pt 0 5.45pt; text-align: center"><B>(Full title of the plan)</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.15pt 3.55pt 0 5.45pt; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.15pt 3.55pt 0 5.45pt; text-align: center"><B>Dr. Phoebe Mounts, Esq.</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.15pt 3.55pt 0 5.45pt; text-align: center"><B>Executive Vice President
  and General Counsel</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.15pt 3.55pt 0 5.45pt; text-align: center"><B>CorMedix Inc.</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.15pt 3.55pt 0 5.45pt; text-align: center"><B>400 Connell Drive, Suite
  5000</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.15pt 3.55pt 0 5.45pt; text-align: center"><B>Berkeley Heights, NJ
  07922</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 213.3pt; text-align: center"><B>(908) 517-9500</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.05pt 0 0; text-align: center">(Name, address, including
  zip code, and telephone number, including area code, of agent for service)</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.05pt 110.35pt 0 110.4pt; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.05pt 110.35pt 0 110.4pt; text-align: center">COPIES TO:</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.05pt 5.45pt 0; text-align: center"><B>Steven A. Navarro</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.05pt 5.45pt 0; text-align: center"><B>Morgan, Lewis &amp; Bockius
  LLP</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.05pt 5.45pt 0; text-align: center"><B>101 Park Avenue</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.05pt 5.45pt 0; text-align: center"><B>New York, New York 10178</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.05pt 5.45pt 0; text-align: center"><B>(212) 309-6000<BR>
  </B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.2pt 5.5pt 0 5.45pt; text-align: center">_____________________</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.55pt 0 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 11pt 0 5.8pt">Indicate by check mark whether the Registrant is a
  large accelerated filer, an accelerated filer, a nonaccelerated filer, a smaller reporting company or an emerging growth company.
  See the definitions of &ldquo;large accelerated filer,&rdquo; &ldquo;accelerated filer,&rdquo; &ldquo;smaller reporting company&rdquo;
  and &ldquo;emerging growth company&rdquo; in Rule 12b-2 of the Act. (Check one):</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 11pt 0 5.8pt">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 10%">&nbsp;</TD>
      <TD STYLE="width: 25%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Large accelerated filer &#9744;</FONT></TD>
      <TD STYLE="width: 30%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Accelerated filer &#9744;</FONT></TD>
      <TD STYLE="width: 25%">&nbsp;</TD>
      <TD STYLE="width: 10%">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Nonaccelerated filer &#9746;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Smaller reporting company &#9746;</FONT></TD>
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Emerging Growth Company &#9744;</FONT></TD>
      <TD>&nbsp;</TD></TR>
  </TABLE>
  
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 11pt 0 5.8pt">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 2.4pt 0 0 4.5pt">If an emerging growth company, indicate by check mark
  if the Registrant has elected not to use the extended transition period for complying with any new or revised financial accounting
  standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. <FONT STYLE="font-family: Times New Roman, Times, Serif">&#9744;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0.2pt; text-align: center; margin-bottom: 0">_____________________</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.35pt 0 0">&nbsp;</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 5.45pt; text-align: center">CALCULATION OF REGISTRATION FEE</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.4pt 0 0"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.4pt 0 0"><B></B></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%; font: 10pt Times New Roman, Times, Serif">
  <TR STYLE="vertical-align: bottom">
      <TD STYLE="font-weight: bold; text-align: center; border-bottom: Black 1.5pt solid">Title of Securities to be Registered</TD><TD STYLE="font-weight: bold; padding-bottom: 1.5pt">&nbsp;</TD>
      <TD COLSPAN="3" STYLE="font-weight: bold; text-align: center; border-bottom: Black 1.5pt solid">Amount to be Registered (1)(2)</TD><TD STYLE="font-weight: bold; padding-bottom: 1.5pt">&nbsp;</TD>
      <TD COLSPAN="3" STYLE="font-weight: bold; text-align: center; border-bottom: Black 1.5pt solid">Proposed Maximum Offering Price Per Share (3)</TD><TD STYLE="font-weight: bold; padding-bottom: 1.5pt">&nbsp;</TD>
      <TD COLSPAN="3" STYLE="font-weight: bold; text-align: center; border-bottom: Black 1.5pt solid">Proposed Maximum Aggregate Offering&#9; Price (3)</TD><TD STYLE="font-weight: bold; padding-bottom: 1.5pt">&nbsp;</TD>
      <TD COLSPAN="3" STYLE="font-weight: bold; text-align: center; border-bottom: Black 1.5pt solid">Amount of <BR> Registration Fee</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
      <TD STYLE="width: 28%; padding-bottom: 4pt">Common Stock, $0.001 par value per share</TD><TD STYLE="width: 1%; padding-bottom: 4pt">&nbsp;</TD>
      <TD STYLE="width: 1%; border-bottom: Black 4pt double; text-align: left">&nbsp;</TD><TD STYLE="width: 15%; border-bottom: Black 4pt double; text-align: right">3,000,000</TD><TD STYLE="width: 1%; padding-bottom: 4pt; text-align: left">&nbsp;</TD><TD STYLE="width: 1%; padding-bottom: 4pt">&nbsp;</TD>
      <TD STYLE="width: 1%; border-bottom: Black 4pt double; text-align: left">$</TD><TD STYLE="width: 15%; border-bottom: Black 4pt double; text-align: right">6.18</TD><TD STYLE="width: 1%; padding-bottom: 4pt; text-align: left">&nbsp;</TD><TD STYLE="width: 1%; padding-bottom: 4pt">&nbsp;</TD>
      <TD STYLE="width: 1%; border-bottom: Black 4pt double; text-align: left">$</TD><TD STYLE="width: 15%; border-bottom: Black 4pt double; text-align: right">18,540,000</TD><TD STYLE="width: 1%; padding-bottom: 4pt; text-align: left">&nbsp;</TD><TD STYLE="width: 1%; padding-bottom: 4pt">&nbsp;</TD>
      <TD STYLE="width: 1%; border-bottom: Black 4pt double; text-align: left">$</TD><TD STYLE="width: 15%; border-bottom: Black 4pt double; text-align: right">2,406.49</TD><TD STYLE="width: 1%; padding-bottom: 4pt; text-align: left">&nbsp;</TD></TR>
  </TABLE>
  
  
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.4pt 0 0"><B>&nbsp;<FONT STYLE="font-size: 10pt">&nbsp;</FONT></B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 6pt; margin-left: 0pt; text-indent: 0pt; text-align: justify"><FONT STYLE="font-size: 10pt">(1)
  </FONT>The remaining 522,606 shares under the Registrant&rsquo;s 2013 Stock Incentive Plan were registered under Registration
  Statement No. 333-192840.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.15pt 0 0"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 6pt; margin-left: 0pt; text-indent: 0pt; text-align: justify"><FONT STYLE="font-size: 10pt">(2)
  </FONT>Pursuant to Rule 416(a) of the Securities Act of 1933, as amended (the &ldquo;Securities Act&rdquo;), this Registration
  Statement (the &ldquo;Registration Statement&rdquo;) also covers any additional shares of the Registrant&rsquo;s common stock
  that may become issuable under the Plan as a result of any future stock splits, stock dividends or similar adjustments of the
  Registrant&rsquo;s outstanding common stock.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify">(3) Estimated solely for the purpose
  of calculating the registration fee, based upon the average of the high and low prices of the common stock on the NYSE American
  LLC on December 11, 2019 in accordance with Rule 457(c) and 457(h).</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.55pt 0 0"></P>
  
  <!-- Field: Rule-Page --><DIV STYLE="margin-top: 0; margin-bottom: 0; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 1pt solid; border-bottom: Black 2pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.55pt 0 0"></P>
  
  <!-- Field: Page; Sequence: 1 -->
      <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1.5pt solid"></DIV>
      <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt">&nbsp;</DIV>
      <!-- Field: /Page -->
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.55pt 0 0"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.35pt 0 0">&nbsp;</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 5pt 5.5pt 0 5.45pt; text-align: center">PART I</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 4.15pt 5.45pt 0; text-align: center"><B>INFORMATION REQUIRED IN THE
  SECTION 10(a) PROSPECTUS</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.4pt 0 0"><B>&nbsp;</B></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
  <TD STYLE="width: 0"></TD><TD STYLE="width: 75.85pt"><B>Item 1.</B></TD><TD><B>Plan Information.</B></TD></TR></TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.35pt 0 0"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 11pt 0 5.8pt; text-indent: 0.4in">The information required by Item
  1 is included in documents sent or given by CorMedix Inc. (the &ldquo;Company&rdquo; or the &ldquo;Registrant&rdquo;) to participants
  in the plan covered by the registration statement pursuant to Rule 428(b)(1) of the Securities Act of 1933, as amended (the &ldquo;Securities
  Act&rdquo;) and the introductory note to Part I of Form S-8.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.2pt 0 0">&nbsp;</P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
  <TD STYLE="width: 0"></TD><TD STYLE="width: 75.85pt">Item 2.</TD><TD STYLE="text-align: left">Registrant Information and Employee Plan Annual Information.</TD></TR></TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.4pt 0 0"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 11pt 0 5.8pt; text-indent: 0.4in">The written statement required
  by Item 2 is included in documents sent or given by the Company in the plan covered by this Registration Statement pursuant to
  Rule 428(b)(1) of the Securities Act.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.2pt 0 0">&nbsp;</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 5.5pt 0 5.45pt; text-align: center">PART II</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.2pt 5.45pt 0; text-align: center"><B>INFORMATION REQUIRED IN THE
  REGISTRATION STATEMENT</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.35pt 0 0"><B>&nbsp;</B></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
  <TD STYLE="width: 0"></TD><TD STYLE="width: 71.85pt"><B>Item 3.</B></TD><TD><B>Incorporation of Documents by Reference</B></TD></TR></TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.35pt 0 0"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.05pt 11pt 0 5.8pt; text-indent: 0.4in">The following documents previously
  filed by the Company with the Securities and Exchange Commission (the &ldquo;Commission&rdquo;) are incorporated herein by reference:</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.05pt 0 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 11.8pt 0 5.8pt; text-indent: 0.4in">(a)<FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
  </FONT>The Company&rsquo;s Annual Report on Form 10-K for the fiscal year ended December 31, 2018, filed with the Commission pursuant
  to Section 13 of the Securities Exchange Act of 1934, as amended (the &ldquo;Exchange Act&rdquo;) on March 14, 2019;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 11.8pt 0 34.6pt; text-indent: 0in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 11.8pt 0 5.8pt; text-indent: 0.4in">(b)<FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
  </FONT>The Company&rsquo;s amended Form 10-K/A for the fiscal year ended December 31, 2018, filed pursuant to Section 13 of the
  Exchange Act on May 29, 2019;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 11.8pt 0 5.8pt; text-indent: 0.4in">(c)<FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
  </FONT>The Company&rsquo;s Quarterly Reports on Form 10-Q for the quarters ended March 31, June 30 and September 30, 2019, filed
  pursuant to Section 13 of the Exchange Act on May 13, 2019, August 14, 2019 and November 14, 2019, respectively;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 5pt 16.45pt 0 5.8pt; text-indent: 0.4in">(d)<FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
  </FONT>The Company&rsquo;s Current Reports on Form 8-K filed pursuant to Section 13 of the Exchange Act on January 3, January 16,
  January 17, January 30, February 14, March 4, March 21, March 25, April 11, April 17, July 9, August 15, September 11, September
  20, September 25, October 1, October 16, November 6 and November 27, 2019&#894;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.1pt 0 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 18.05pt 0 5.8pt; text-indent: 0.4in">(e)<FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
  </FONT>The Company&rsquo;s definitive proxy statement on Schedule 14A for the Company&rsquo;s 2019 Annual Meeting of Shareholders,
  filed with the Commission pursuant to Section 14 of the Exchange Act on October 17, 2019&#894; and</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.15pt 0 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 10.45pt 0 5.8pt; text-indent: 0.4in">(f)<FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
  </FONT>The description of the Company&rsquo;s common stock contained in Item 1 of its Registration Statement on Form 8-A (File
  No. 333-163380) filed with the Commission pursuant to Section 12(b) of the Exchange Act on March 19, 2010 and any amendments or
  reports filed for the purpose of updating that description.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 7.15pt 13.5pt 0 5.8pt; text-indent: 0.4in"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 16.5pt 0 5.8pt; text-indent: 0.4in">All documents filed, but
  not furnished, by the Company pursuant to Sections 13(a), 13(c), 14 or 15(d) of the Exchange Act on or after the date hereof and
  prior to the filing of a post-effective amendment to this Registration Statement that indicates that all securities offered under
  this Registration Statement have been sold or which deregisters all securities then remaining unsold shall be deemed to be incorporated
  by reference herein and to be a part hereof from the date of filing of such documents. In no event, however, will any of the information,
  including exhibits, that the Company discloses under Item 2.02 and Item 7.01 of any report on Form 8-K that has been or may be,
  from time to time, furnished to the SEC be incorporated by reference into or otherwise become a part of this Registration Statement.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0; margin-left: 5.8pt; text-indent: 0.4in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 16.5pt 0 5.8pt; text-indent: 0.4in">Any statement contained in a
  document incorporated by reference herein shall be deemed to be modified or superseded for purposes hereof to the extent that a
  statement contained herein (or in any other subsequently filed document that also is or is deemed to be incorporated by reference
  herein) modifies or supersedes such statement. Any statement so modified or superseded shall not be deemed to constitute a part
  hereof except as so modified or superseded.</P>
  
  <!-- Field: Page; Sequence: 2; Options: NewSection -->
      <DIV STYLE="margin-top: 6pt; margin-bottom: 6pt; border-bottom: Black 1.5pt solid"><P STYLE="margin-top: 0pt; text-align: center; margin-bottom: 0pt"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->1<!-- Field: /Sequence -->&nbsp;</P></DIV>
      <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
      <!-- Field: /Page -->
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 16.5pt 0 5.8pt"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 5pt; margin-bottom: 0"><TR STYLE="vertical-align: top">
  <TD STYLE="width: 0"></TD><TD STYLE="width: 75.85pt">Item 4.</TD><TD STYLE="text-align: left">Description of Securities</TD></TR></TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.35pt 0 0"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 34.6pt">Not applicable. The class of securities to be offered
  is registered under Section 12 of the Exchange Act.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.35pt 0 0">&nbsp;</P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
  <TD STYLE="width: 0"></TD><TD STYLE="width: 75.85pt">Item 5.</TD><TD STYLE="text-align: left">Interests of Named Experts and Counsel</TD></TR></TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.4pt 0 0"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 34.6pt">Not applicable.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.35pt 0 0">&nbsp;</P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
  <TD STYLE="width: 0"></TD><TD STYLE="width: 75.85pt">Item 6.</TD><TD STYLE="text-align: left">Indemnification of Directors and Officers</TD></TR></TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.35pt 0 0"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.05pt 6.25pt 0 5.8pt; text-indent: 0.4in">The Company is incorporated
  under the laws of the State of Delaware. Section 145 of the Delaware General Corporation Law (the &ldquo;DGCL&rdquo;) gives a corporation
  the power to indemnify any person who was or is a party or is threatened to be made a party to any threatened, pending or completed
  action, suit or proceeding, whether civil, criminal, administrative or investigative (other than an action by or in the right of
  the corporation) by reason of the fact that the person is or was a director, officer, employee or agent of the corporation, or
  is or was serving at the request of the corporation as a director, officer, employee or agent of another corporation, partnership,
  joint venture, trust or other enterprise, against expenses (including attorneys&rsquo; fees), judgments, fines and amounts paid
  in settlement actually and reasonably incurred by the person in connection with such action, suit or proceeding if the person acted
  in good faith and in a manner the person reasonably believed to be in or not opposed to the best interests of the corporation,
  and, with respect to any criminal action or proceeding, had no reasonable cause to believe the person&rsquo;s conduct was unlawful.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.25pt 0 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 13.75pt 0 5.8pt; text-indent: 0.4in">Section 145 of the DGCL also
  gives a corporation the power to indemnify any person who was or is a party or is threatened to be made a party to any threatened,
  pending or completed action or suit by or in the right of the corporation to procure a judgment in its favor by reason of the fact
  that the person is or was a director, officer, employee or agent of the corporation, or is or was serving at the request of the
  corporation as a director, officer, employee or agent of another corporation, partnership, joint venture, trust or other enterprise
  against expenses (including attorneys&rsquo; fees) actually and reasonably incurred by the person in connection with the defense
  or settlement of such action or suit if the person acted in good faith and in a manner the person reasonably believed to be in
  or not opposed to the best interests of the corporation and except that no indemnification shall be made in respect of any claim,
  issue or matter as to which such person shall have been adjudged to be liable to the corporation unless and only to the extent
  that the Court of Chancery or the court in which such action or suit was brought shall determine upon application that, despite
  the adjudication of liability but in view of all the circumstances of the case, such person is fairly and reasonably entitled to
  indemnity for such expenses which the Court of Chancery or such other court shall deem proper. Section 145 further provides that,
  to the extent that a present or former director or officer of a corporation has been successful on the merits or otherwise in defense
  of any such action, suit or proceeding, or in defense of any claim, issue or matter therein, such person shall be indemnified against
  expenses (including attorneys&rsquo; fees) actually and reasonably incurred by such person in connection therewith.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.35pt 0 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 12.9pt 0 5.8pt; text-indent: 0.4in">Section 145 of the DGCL also
  authorizes a corporation to purchase and maintain insurance on behalf of any person who is or was a director, officer, employee
  or agent of the corporation, or is or was serving at the request of the corporation as a director, officer, employee or agent of
  another corporation, partnership, joint venture, trust or other enterprise, against any liability asserted against him and incurred
  by him in any such capacity, arising out of his status as such, whether or not the corporation would otherwise have the power to
  indemnify him under Section 145 of the DGCL.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.25pt 0 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 11pt 0 5.8pt; text-indent: 0.4in">The Company&rsquo;s Certificate
  of Incorporation, as amended, and Bylaws, as amended, provide for the indemnification of officers and directors to the fullest
  extent permitted by the DGCL.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.2pt 0 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 16.5pt 0 5.8pt; text-indent: 0.4in">All of the Company&rsquo;s directors
  and officers are covered by insurance policies maintained by the Company against certain liabilities for actions taken in their
  capacities as such, including liabilities under the Securities Act.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 16.5pt 0 5.8pt; text-indent: 0.4in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 16.5pt 0 5.8pt; text-indent: 0.4in">The foregoing is only a general
  summary of certain aspects of the DGCL and the Company&rsquo;s Certificate of Incorporation, as amended, and Bylaws, as amended,
  dealing with indemnification of directors and officers, and does not purport to be complete. It is qualified in its entirety by
  reference to the detailed provisions of Section 145 of the Delaware Corporation Law and of the Company&rsquo;s Certificate of Incorporation,
  as amended, and Bylaws, as amended.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 16.5pt 0 5.8pt; text-indent: 0.4in">&nbsp;</P>
  
  <!-- Field: Page; Sequence: 3 -->
      <DIV STYLE="margin-top: 6pt; margin-bottom: 6pt; border-bottom: Black 1.5pt solid"><P STYLE="margin-top: 0pt; text-align: center; margin-bottom: 0pt"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->2<!-- Field: /Sequence -->&nbsp;</P></DIV>
      <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
      <!-- Field: /Page -->
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 16.5pt 0 5.8pt"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.2pt 0 0">&nbsp;</P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0.05pt; margin-bottom: 0"><TR STYLE="vertical-align: top">
  <TD STYLE="width: 0"></TD><TD STYLE="width: 75.85pt">Item 7.</TD><TD STYLE="text-align: left">Exemption From Registration Claimed</TD></TR></TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.35pt 0 0"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 34.6pt">Not applicable.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.35pt 0 0">&nbsp;</P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
  <TD STYLE="width: 0"></TD><TD STYLE="width: 75.85pt">Item 8.</TD><TD STYLE="text-align: left">Exhibits</TD></TR></TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.4pt 0 0"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 34.6pt">The following exhibits are filed as part of this Registration
  Statement:</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 34.6pt">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.15pt 0 0 5.8pt"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.2pt 0 0 5.8pt"></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0.2pt; margin-bottom: 0">                                                                                                                                                                                                                                                                                                                                                                                                                              <TR STYLE="vertical-align: top">
  <TD STYLE="border-bottom: Black 1pt solid">Exhibit No.&#9;</TD><TD STYLE="padding-bottom: 1pt">&nbsp;</TD><TD STYLE="border-bottom: Black 1pt solid">Description</TD></TR>
  <TR STYLE="vertical-align: top; background-color: rgb(204,238,255)">
  <TD>5.1</TD><TD>&nbsp;</TD><TD><A HREF="fs81219ex5-1_cormedix.htm">Opinion of Morgan, Lewis &amp; Bockius LLP.</A></TD></TR>
  <TR STYLE="vertical-align: top; background-color: White">
  <TD>10.1</TD><TD>&nbsp;</TD><TD><A HREF="http://www.sec.gov/Archives/edgar/data/1410098/000121390019024927/f8k112619ex10-1_cormedix.htm">CorMedix Inc. 2019 Omnibus Stock Incentive Plan (incorporated by reference to Exhibit 10.1 to the Company&rsquo;s Current Report on Form 8-K filed &#9;on November 27, 2019).</A></TD></TR>
  <TR STYLE="vertical-align: top; background-color: rgb(204,238,255)">
  <TD STYLE="width: 10%">23.1</TD><TD STYLE="width: 1%">&nbsp;</TD><TD><A HREF="fs81219ex23-1_cormedix.htm" STYLE="-sec-extract: exhibit">Consent of Friedman LLP, Independent Registered Public Accounting Firm.</A></TD></TR>                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         <TR STYLE="vertical-align: top; background-color: White">
  <TD>23.2</TD><TD>&nbsp;</TD><TD><A HREF="fs81219ex5-1_cormedix.htm">Consent of Morgan, Lewis &amp; Bockius LLP (contained in Exhibit 5.1).</A></TD></TR>
  <TR STYLE="vertical-align: top; background-color: rgb(204,238,255)">
  <TD>24.1</TD><TD>&nbsp;</TD><TD><A HREF="#Signatures">Power of Attorney (see page S-1).</A></TD></TR>
  </TABLE>
  
  
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.2pt 0 0 5.8pt">_______________________</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.35pt 0 0">&nbsp;</P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
  <TD STYLE="width: 0"></TD><TD STYLE="width: 75.85pt">Item 9.</TD><TD STYLE="text-align: left">Undertakings</TD></TR></TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.25pt 0 0"><B>&nbsp;</B></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
  <TD STYLE="width: 34.55pt"></TD><TD STYLE="width: 18.55pt">(a)</TD><TD>The undersigned Registrant hereby undertakes as follows:</TD></TR></TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.15pt 0 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 4.5pt; text-indent: 57.5pt"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 4.5pt; text-indent: 57.5pt">(1)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
  To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement to
  include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement
  or any material change to such information in the Registration Statement.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.05pt 0 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 13.25pt 0 5.8pt; text-indent: 57.65pt">(2)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
  That, for the purpose of determining any liability under the Securities Act of 1933, each such post-effective amendment shall be
  deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that
  time shall be deemed to be the initial bona fide offering thereof.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.55pt 0 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 27.8pt 0 5.8pt; text-indent: 57.65pt">(3)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
  To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at
  the termination of the offering.</P>
  
  
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 27.8pt 0 5.8pt; text-indent: 57.65pt"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.1pt 0 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.05pt 10.85pt 0 5.8pt; text-indent: 0.4in">(b)<FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
  </FONT>The undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act of
  1933, each filing of the Registrant&rsquo;s annual report pursuant to Section 13(a) or Section 15(d) of the Securities Exchange
  Act of 1934 (and, where applicable, each filing of an employee benefit plan&rsquo;s annual report pursuant to Section 15(d) of
  the Securities Exchange Act of 1934) that is incorporated by reference in the Registration Statement shall be deemed to be a new
  registration statement related to the securities offered therein, and the offering of such securities at the time shall be deemed
  to be the initial</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.15pt 0 0 5.8pt">bona fide offering thereof.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.25pt 0 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 8.7pt 0 5.8pt; text-indent: 0.4in"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.05pt 10.85pt 0 5.8pt; text-indent: 0.4in">(c)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
  Insofar as indemnification for liabilities arising under the Securities Act of 1933 may be permitted to directors, officers
  and controlling persons of the Registrant pursuant to the foregoing provisions, or otherwise, the Registrant has been advised
  that in the opinion of the Securities and Exchange Commission such indemnification is against public policy as expressed in
  the Act and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than
  the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant in
  the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in
  connection with the securities being Registered, the Registrant will, unless in the opinion of its counsel the matter has
  been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such
  indemnification by it is against public policy as expressed in the Act and will be governed by the final adjudication of such
  issue.</P>
  
  
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.2pt 16.5pt 0 5.8pt"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.2pt 0 0">&nbsp;</P>
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0.05pt 5.5pt 0 5.45pt; text-align: center">[THE NEXT PAGE IS
  THE SIGNATURE PAGE]</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.4pt 0 0">&nbsp;</P>
  
  <!-- Field: Page; Sequence: 4 -->
      <DIV STYLE="margin-top: 6pt; margin-bottom: 6pt; border-bottom: Black 1.5pt solid"><P STYLE="margin-top: 0pt; text-align: center; margin-bottom: 0pt"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->3<!-- Field: /Sequence -->&nbsp;</P></DIV>
      <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
      <!-- Field: /Page -->
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.4pt 0 0"></P>
  
  
  
  
  <P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 4.95pt 5.5pt 0 5.45pt; text-align: center">SIGNATURES</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.45pt 0 0"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 11pt 0 5.8pt; text-indent: 0.4in">Pursuant to the requirements
  of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets
  all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by
  the undersigned, thereunto duly authorized, in the Town of Berkeley Heights, State of New Jersey, on the  17<SUP>th</SUP> day
  of December 2019.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.3pt 0 0">&nbsp;</P>
  
  <TABLE BORDER="0" CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif">
  <TR>
      <TD STYLE="vertical-align: top"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD COLSPAN="2"><FONT STYLE="font-size: 10pt"><B>CORMEDIX INC.</B></FONT></TD></TR>
  <TR>
      <TD STYLE="vertical-align: top"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD COLSPAN="2"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR>
      <TD STYLE="vertical-align: top; width: 50%"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="width: 4%"><FONT STYLE="font-size: 10pt">By:&nbsp;</FONT></TD>
      <TD STYLE="vertical-align: top; width: 46%"><FONT STYLE="font-size: 10pt">/s/ Khoso Baluch</FONT></TD></TR>
  <TR>
      <TD STYLE="vertical-align: top"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="vertical-align: top; border-top: #000000 1px solid"><FONT STYLE="font-size: 10pt">Khoso Baluch<BR>Chief Executive
      Officer</FONT></TD></TR>
  </TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left; text-indent: 0pt; margin-top: 0pt; margin-bottom: 6pt">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0pt; margin-bottom: 0"><B><A NAME="Signatures"></A>POWER OF ATTORNEY</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0pt; margin-bottom: 0"><B>&nbsp;</B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 13.6pt 0 5.8pt; text-indent: 0.4in"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 13.6pt 0 5.8pt; text-indent: 0.4in">Each person whose signature appears
  below constitutes and appoints Khoso Baluch and Phoebe Mounts, and each of them, his or her true and lawful attorney-in-fact and
  agent, with full power of substitution and re-substitution, for him or her and in his or her name, place and stead, in any and
  all capacities, to sign any and all amendments (including post-effective amendments) to this Registration Statement, and to file
  the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission,
  granting unto said attorney-in-fact and agent full power and authority to do and perform each and every act and thing requisite
  and necessary to be done in and about the premises, as fully to all intents and purposes as he might or could do in person, hereby
  ratifying and confirming all that said attorney-in-fact and agent, or his substitute or substitutes, may lawfully do or cause to
  be done by virtue hereof.</P>
  
  
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 13.6pt 0 5.8pt; text-indent: 0.4in"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0.25pt 0 0">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 11pt 0 5.8pt; text-indent: 0.4in">Pursuant to the requirements of
  the Securities Act of 1933, this Registration Statement has been signed by the following persons in the capacities and on the dates
  indicated.</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 11pt 0 5.8pt; text-indent: 0.4in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 11pt 0 5.8pt; text-indent: 0.4in"></P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 100%">
  <TR STYLE="vertical-align: top">
      <TD STYLE="width: 183.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Signature</B></FONT></TD>
      <TD STYLE="width: 181.45pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Capacity</B></FONT></TD>
      <TD STYLE="width: 181.05pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Date</B></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Khoso Baluch&nbsp;</FONT></TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director and Chief Executive Officer</FONT></TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">December 17, 2019</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Khoso Baluch&#9;</FONT></TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Principal Executive Officer)</FONT></TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;/s/ Robert W. Cook</FONT></TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Chief Financial Officer</FONT></TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">December 17, 2019</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Robert W. Cook</FONT></TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Principal Financial Officer and Principal Accounting Officer)</FONT></TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Janet Dillione</FONT></TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</FONT></TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">December 17, 2019</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Janet Dillione</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;/s/ Alan W. Dunton</FONT></TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;Director</FONT></TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">December 17, 2019</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;Alan W. Dunton</FONT></TD>
      <TD>&nbsp;</TD>
      <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Myron Kaplan&nbsp;</FONT></TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director and Chairman of the Board</FONT></TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Myron Kaplan</FONT></TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">December 17, 2019</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Mehmood Khan</FONT></TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;Director</FONT></TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Mehmood Khan</FONT></TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">December 17, 2019</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD STYLE="border-bottom: black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Steven Lefkowitz&nbsp;</FONT></TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;Director</FONT></TD>
      <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
      <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Steven Lefkowitz</FONT></TD>
      <TD>&nbsp;</TD>
      <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">December 17, 2019</FONT></TD></TR>
  </TABLE>
  
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 11pt 0 5.8pt; text-indent: 0.4in"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 11pt 0 5.8pt; text-indent: 0.4in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 11pt 0 5.8pt; text-indent: 0.4in">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"></P>
  
  <!-- Field: Page; Sequence: 5; Options: Last -->
      <DIV STYLE="margin-top: 6pt; margin-bottom: 6pt; border-bottom: Black 1.5pt solid"><P STYLE="margin-top: 0pt; text-align: center; margin-bottom: 0pt"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->4<!-- Field: /Sequence -->&nbsp;</P></DIV>
      <!-- Field: /Page -->
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"></P>
  
  </BODY>
  </HTML>
metadata_documents: [{"type": "S-8", "sequence": "1", "filename": "fs81219_cormedix.htm", "description": "REGISTRATION STATEMENT", "secsgml_size_bytes": 58565}]
metadata_filer: {"company-data": {"conformed-name": "CorMedix Inc.", "cik": "0001410098", "assigned-sic": "2834", "irs-number": "000000000", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-235556", "film-number": "191290650"}, "business-address": {"street1": "400 CONNELL DRIVE", "street2": "SUITE 5000", "city": "BERKELEY HEIGHTS", "state": "NJ", "zip": "07922", "phone": "908-517-9500"}, "mail-address": {"street1": "400 CONNELL DRIVE", "street2": "SUITE 5000", "city": "BERKELEY HEIGHTS", "state": "NJ", "zip": "07922"}}
text: As filed with the Securities
  and Exchange Commission on December 17, 2019
  Registration Statement No.
  333-
  UNITED STATES
  SECURITIES AND EXCHANGE COMMISSION
  Washington, D.C. 20549
  FORM S-8
  REGISTRATION STATEMENT UNDER
  THE SECURITIES ACT OF 1933
  _____________________
  CORMEDIX INC.
  (Exact name of registrant
  as specified in its charter)
  Delaware
  20-5894890
  (State of other jurisdiction
          of
  incorporation or organization)
  (I.R.S. Employer
  Identification No.)
  400 Connell Drive, Suite
          5000
  Berkeley Heights, NJ
  07922
  (Address of principal executive offices)
  (Zip Code)
  CorMedix Inc. 2019 Omnibus
  Stock Incentive Plan
  (Full title of the plan)
  Dr. Phoebe Mounts, Esq.
  Executive Vice President
  and General Counsel
  CorMedix Inc.
  400 Connell Drive, Suite
  5000
  Berkeley Heights, NJ
  07922
  (908) 517-9500
  (Name, address, including
  zip code, and telephone number, including area code, of agent for service)
  COPIES TO:
  Steven A. Navarro
  Morgan, Lewis & Bockius
  LLP
  101 Park Avenue
  New York, New York 10178
  (212) 309-6000
  _____________________
  Indicate by check mark whether the Registrant is a
  large accelerated filer, an accelerated filer, a nonaccelerated filer, a smaller reporting company or an emerging growth company.
  See the definitions of "large accelerated filer," "accelerated filer," "smaller reporting company"
  and "emerging growth company" in Rule 12b-2 of the Act. (Check one):
  Large accelerated filer ☐
  Accelerated filer ☐
  Nonaccelerated filer ☒
  Smaller reporting company ☒
  Emerging Growth Company ☐
  If an emerging growth company, indicate by check mark
  if the Registrant has elected not to use the extended transition period for complying with any new or revised financial accounting
  standards provided pursuant to Section 7(a)(2)(B) of the Securities Act.
  ☐
  _____________________
  CALCULATION OF REGISTRATION FEE
  Title of Securities to be Registered
  Amount to be Registered (1)(2)
  Proposed Maximum Offering Price Per Share (3)
  Proposed Maximum Aggregate Offering	 Price (3)
  Amount of
  Registration Fee
  Common Stock, $0.001 par value per share
  3,000,000
  $
  6.18
  $
  18,540,000
  $
  2,406.49
  (1)
  The remaining 522,606 shares under the Registrant's 2013 Stock Incentive Plan were registered under Registration
  Statement No. 333-192840.
  (2)
  Pursuant to Rule 416(a) of the Securities Act of 1933, as amended (the "Securities Act"), this Registration
  Statement (the "Registration Statement") also covers any additional shares of the Registrant's common stock
  that may become issuable under the Plan as a result of any future stock splits, stock dividends or similar adjustments of the
  Registrant's outstanding common stock.
  (3) Estimated solely for the purpose
  of calculating the registration fee, based upon the average of the high and low prices of the common stock on the NYSE American
  LLC on December 11, 2019 in accordance with Rule 457(c) and 457(h).
  PART I
  INFORMATION REQUIRED IN THE
  SECTION 10(a) PROSPECTUS
  Item 1.
  Plan Information.
  The information required by Item
  1 is included in documents sent or given by CorMedix Inc. (the "Company" or the "Registrant") to participants
  in the plan covered by the registration statement pursuant to Rule 428(b)(1) of the Securities Act of 1933, as amended (the "Securities
  Act") and the introductory note to Part I of Form S-8.
  Item 2.
  Registrant Information and Employee Plan Annual Information.
  The written statement required
  by Item 2 is included in documents sent or given by the Company in the plan covered by this Registration Statement pursuant to
  Rule 428(b)(1) of the Securities Act.
  PART II
  INFORMATION REQUIRED IN THE
  REGISTRATION STATEMENT
  Item 3.
  Incorporation of Documents by Reference
  The following documents previously
  filed by the Company with the Securities and Exchange Commission (the "Commission") are incorporated herein by reference:
  (a)
  The Company's Annual Report on Form 10-K for the fiscal year ended December 31, 2018, filed with the Commission pursuant
  to Section 13 of the Securities Exchange Act of 1934, as amended (the "Exchange Act") on March 14, 2019;
  (b)
  The Company's amended Form 10-K/A for the fiscal year ended December 31, 2018, filed pursuant to Section 13 of the
  Exchange Act on May 29, 2019;
  (c)
  The Company's Quarterly Reports on Form 10-Q for the quarters ended March 31, June 30 and September 30, 2019, filed
  pursuant to Section 13 of the Exchange Act on May 13, 2019, August 14, 2019 and November 14, 2019, respectively;
  (d)
  The Company's Current Reports on Form 8-K filed pursuant to Section 13 of the Exchange Act on January 3, January 16,
  January 17, January 30, February 14, March 4, March 21, March 25, April 11, April 17, July 9, August 15, September 11, September
  20, September 25, October 1, October 16, November 6 and November 27, 2019;
  (e)
  The Company's definitive proxy statement on Schedule 14A for the Company's 2019 Annual Meeting of Shareholders,
  filed with the Commission pursuant to Section 14 of the Exchange Act on October 17, 2019; and
  (f)
  The description of the Company's common stock contained in Item 1 of its Registration Statement on Form 8-A (File
  No. 333-163380) filed with the Commission pursuant to Section 12(b) of the Exchange Act on March 19, 2010 and any amendments or
  reports filed for the purpose of updating that description.
  All documents filed, but
  not furnished, by the Company pursuant to Sections 13(a), 13(c), 14 or 15(d) of the Exchange Act on or after the date hereof and
  prior to the filing of a post-effective amendment to this Registration Statement that indicates that all securities offered under
  this Registration Statement have been sold or which deregisters all securities then remaining unsold shall be deemed to be incorporated
  by reference herein and to be a part hereof from the date of filing of such documents. In no event, however, will any of the information,
  including exhibits, that the Company discloses under Item 2.02 and Item 7.01 of any report on Form 8-K that has been or may be,
  from time to time, furnished to the SEC be incorporated by reference into or otherwise become a part of this Registration Statement.
  Any statement contained in a
  document incorporated by reference herein shall be deemed to be modified or superseded for purposes hereof to the extent that a
  statement contained herein (or in any other subsequently filed document that also is or is deemed to be incorporated by reference
  herein) modifies or supersedes such statement. Any statement so modified or superseded shall not be deemed to constitute a part
  hereof except as so modified or superseded.
  1
  Item 4.
  Description of Securities
  Not applicable. The class of securities to be offered
  is registered under Section 12 of the Exchange Act.
  Item 5.
  Interests of Named Experts and Counsel
  Not applicable.
  Item 6.
  Indemnification of Directors and Officers
  The Company is incorporated
  under the laws of the State of Delaware. Section 145 of the Delaware General Corporation Law (the "DGCL") gives a corporation
  the power to indemnify any person who was or is a party or is threatened to be made a party to any threatened, pending or completed
  action, suit or proceeding, whether civil, criminal, administrative or investigative (other than an action by or in the right of
  the corporation) by reason of the fact that the person is or was a director, officer, employee or agent of the corporation, or
  is or was serving at the request of the corporation as a director, officer, employee or agent of another corporation, partnership,
  joint venture, trust or other enterprise, against expenses (including attorneys' fees), judgments, fines and amounts paid
  in settlement actually and reasonably incurred by the person in connection with such action, suit or proceeding if the person acted
  in good faith and in a manner the person reasonably believed to be in or not opposed to the best interests of the corporation,
  and, with respect to any criminal action or proceeding, had no reasonable cause to believe the person's conduct was unlawful.
  Section 145 of the DGCL also
  gives a corporation the power to indemnify any person who was or is a party or is threatened to be made a party to any threatened,
  pending or completed action or suit by or in the right of the corporation to procure a judgment in its favor by reason of the fact
  that the person is or was a director, officer, employee or agent of the corporation, or is or was serving at the request of the
  corporation as a director, officer, employee or agent of another corporation, partnership, joint venture, trust or other enterprise
  against expenses (including attorneys' fees) actually and reasonably incurred by the person in connection with the defense
  or settlement of such action or suit if the person acted in good faith and in a manner the person reasonably believed to be in
  or not opposed to the best interests of the corporation and except that no indemnification shall be made in respect of any claim,
  issue or matter as to which such person shall have been adjudged to be liable to the corporation unless and only to the extent
  that the Court of Chancery or the court in which such action or suit was brought shall determine upon application that, despite
  the adjudication of liability but in view of all the circumstances of the case, such person is fairly and reasonably entitled to
  indemnity for such expenses which the Court of Chancery or such other court shall deem proper. Section 145 further provides that,
  to the extent that a present or former director or officer of a corporation has been successful on the merits or otherwise in defense
  of any such action, suit or proceeding, or in defense of any claim, issue or matter therein, such person shall be indemnified against
  expenses (including attorneys' fees) actually and reasonably incurred by such person in connection therewith.
  Section 145 of the DGCL also
  authorizes a corporation to purchase and maintain insurance on behalf of any person who is or was a director, officer, employee
  or agent of the corporation, or is or was serving at the request of the corporation as a director, officer, employee or agent of
  another corporation, partnership, joint venture, trust or other enterprise, against any liability asserted against him and incurred
  by him in any such capacity, arising out of his status as such, whether or not the corporation would otherwise have the power to
  indemnify him under Section 145 of the DGCL.
  The Company's Certificate
  of Incorporation, as amended, and Bylaws, as amended, provide for the indemnification of officers and directors to the fullest
  extent permitted by the DGCL.
  All of the Company's directors
  and officers are covered by insurance policies maintained by the Company against certain liabilities for actions taken in their
  capacities as such, including liabilities under the Securities Act.
  The foregoing is only a general
  summary of certain aspects of the DGCL and the Company's Certificate of Incorporation, as amended, and Bylaws, as amended,
  dealing with indemnification of directors and officers, and does not purport to be complete. It is qualified in its entirety by
  reference to the detailed provisions of Section 145 of the Delaware Corporation Law and of the Company's Certificate of Incorporation,
  as amended, and Bylaws, as amended.
  2
  Item 7.
  Exemption From Registration Claimed
  Not applicable.
  Item 8.
  Exhibits
  The following exhibits are filed as part of this Registration
  Statement:
  Exhibit No.
  Description
  5.1
  Opinion of Morgan, Lewis & Bockius LLP.
  10.1
  CorMedix Inc. 2019 Omnibus Stock Incentive Plan (incorporated by reference to Exhibit 10.1 to the Company's Current Report on Form 8-K filed 	on November 27, 2019).
  23.1
  Consent of Friedman LLP, Independent Registered Public Accounting Firm.
  23.2
  Consent of Morgan, Lewis & Bockius LLP (contained in Exhibit 5.1).
  24.1
  Power of Attorney (see page S-1).
  _______________________
  Item 9.
  Undertakings
  (a)
  The undersigned Registrant hereby undertakes as follows:
  (1)               
  To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement to
  include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement
  or any material change to such information in the Registration Statement.
  (2)      
  That, for the purpose of determining any liability under the Securities Act of 1933, each such post-effective amendment shall be
  deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that
  time shall be deemed to be the initial bona fide offering thereof.
  (3)      
  To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at
  the termination of the offering.
  (b)
  The undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act of
  1933, each filing of the Registrant's annual report pursuant to Section 13(a) or Section 15(d) of the Securities Exchange
  Act of 1934 (and, where applicable, each filing of an employee benefit plan's annual report pursuant to Section 15(d) of
  the Securities Exchange Act of 1934) that is incorporated by reference in the Registration Statement shall be deemed to be a new
  registration statement related to the securities offered therein, and the offering of such securities at the time shall be deemed
  to be the initial
  bona fide offering thereof.
  (c)       
  Insofar as indemnification for liabilities arising under the Securities Act of 1933 may be permitted to directors, officers
  and controlling persons of the Registrant pursuant to the foregoing provisions, or otherwise, the Registrant has been advised
  that in the opinion of the Securities and Exchange Commission such indemnification is against public policy as expressed in
  the Act and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than
  the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant in
  the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in
  connection with the securities being Registered, the Registrant will, unless in the opinion of its counsel the matter has
  been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such
  indemnification by it is against public policy as expressed in the Act and will be governed by the final adjudication of such
  issue.
  [THE NEXT PAGE IS
  THE SIGNATURE PAGE]
  3
  SIGNATURES
  Pursuant to the requirements
  of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets
  all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by
  the undersigned, thereunto duly authorized, in the Town of Berkeley Heights, State of New Jersey, on the  17
  th
  day
  of December 2019.
  CORMEDIX INC.
  By:
  /s/ Khoso Baluch
  Khoso Baluch
  Chief Executive
      Officer
  POWER OF ATTORNEY
  Each person whose signature appears
  below constitutes and appoints Khoso Baluch and Phoebe Mounts, and each of them, his or her true and lawful attorney-in-fact and
  agent, with full power of substitution and re-substitution, for him or her and in his or her name, place and stead, in any and
  all capacities, to sign any and all amendments (including post-effective amendments) to this Registration Statement, and to file
  the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission,
  granting unto said attorney-in-fact and agent full power and authority to do and perform each and every act and thing requisite
  and necessary to be done in and about the premises, as fully to all intents and purposes as he might or could do in person, hereby
  ratifying and confirming all that said attorney-in-fact and agent, or his substitute or substitutes, may lawfully do or cause to
  be done by virtue hereof.
  Pursuant to the requirements of
  the Securities Act of 1933, this Registration Statement has been signed by the following persons in the capacities and on the dates
  indicated.
  Signature
  Capacity
  Date
  /s/ Khoso Baluch
  Director and Chief Executive Officer
  December 17, 2019
  Khoso Baluch
  (Principal Executive Officer)
  /s/ Robert W. Cook
  Chief Financial Officer
  December 17, 2019
  Robert W. Cook
  (Principal Financial Officer and Principal Accounting Officer)
  /s/ Janet Dillione
  Director
  December 17, 2019
  Janet Dillione
  /s/ Alan W. Dunton
  Director
  December 17, 2019
  Alan W. Dunton
  /s/ Myron Kaplan
  Director and Chairman of the Board
  Myron Kaplan
  December 17, 2019
  /s/ Mehmood Khan
  Director
  Mehmood Khan
  December 17, 2019
  /s/ Steven Lefkowitz
  Director
  Steven Lefkowitz
  December 17, 2019
  4