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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">As
  filed with the Securities and Exchange Commission on December 27, 2021</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif">Registration
  No. ______</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right"></P>
  
  <!-- Field: Rule-Page --><DIV STYLE="font-family: Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; width: 100%"><DIV STYLE="font: 1pt Times New Roman, Times, Serif; border-top: Black 2pt solid; border-bottom: Black 1pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></DIV></DIV><!-- Field: /Rule-Page -->
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right"></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>UNITED
  STATES</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>SECURITIES
  AND EXCHANGE COMMISSION</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>WASHINGTON,
  D.C. 20549</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">_______________________</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>&nbsp;</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>FORM
  S-8</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>REGISTRATION
  STATEMENT</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>UNDER
  THE SECURITIES ACT OF 1933</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>TFF
  Pharmaceuticals, Inc.</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">(Exact
  name of registrant as specified in its charter)</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="font-family: Times New Roman, Times, Serif; border-bottom: Black 1.5pt solid; padding-top: 0; padding-right: 0; padding-left: 0; width: 49%; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>Delaware</B></FONT></P></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-bottom: 1.5pt; width: 2%"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font: 10pt Times New Roman, Times, Serif; border-bottom: Black 1.5pt solid; padding-top: 0; padding-right: 0; padding-left: 0; width: 49%; text-align: center; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>82-4344737</B></FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding: 0; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">(State
      or other jurisdiction of</FONT></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">incorporation
      or organization)</FONT></P></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding: 0; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">(I.R.S.
      Employer</FONT></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">Identification
      No.)</FONT></P></TD></TR>
    </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="font: 10pt Times New Roman, Times, Serif; border-bottom: Black 1.5pt solid; width: 49%; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>3801
      S. Capital of Texas Hwy, Suite 330<BR>
      Austin, Texas</B></FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-bottom: 1.5pt; width: 2%"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; border-bottom: Black 1.5pt solid; width: 49%; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>&nbsp;</B></FONT></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>78704</B></FONT></P></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="font: 10pt Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Address
      of Principal Executive Offices)</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font: 10pt Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Zip
      Code)</FONT></TD></TR>
    </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">_______________________</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>&nbsp;</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>2021
  Stock Incentive Plan</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Full
  title of the plan)<BR>
  </FONT><FONT STYLE="font-family: Times New Roman, Times, Serif">_______________________</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>&nbsp;</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>Glenn
  Mattes<BR>
  Chief Executive Officer<BR>
  3801 S. Capital of Texas Hwy, Suite 330<BR>
  Austin, Texas 78704<BR>
  </B>(Name and address of agent for service)</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>&nbsp;</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>(737)
  802-1973</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">(Telephone
  number, including area code, of agent for service)</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B><I>&nbsp;</I></B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B><I>Copy
  to:</I></B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>Daniel
  K. Donahue</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>Greenberg
  Traurig, LLP</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>18565
  Jamboree Road, Suite 500</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>Irvine,
  California 92612</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>(949)
  732-6500</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Indicate
  by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting
  company or an emerging growth company. See the definitions of &ldquo;large accelerated filer,&rdquo; &ldquo;accelerated filer,&rdquo;
  &ldquo;smaller reporting company,&rdquo; and &ldquo;emerging growth company&rdquo; in Rule 12b-2 of the Exchange Act.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" ALIGN="CENTER" STYLE="font: 10pt Times New Roman, Times, Serif; width: 90%; border-collapse: collapse">
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="font-family: Times New Roman, Times, Serif; width: 26%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Large
      accelerated filer </FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; width: 25%"><FONT STYLE="font-family: Times New Roman, Times, Serif">&#9744;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; width: 25%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Accelerated
      filer </FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; width: 24%"><FONT STYLE="font-family: Times New Roman, Times, Serif">&#9744;</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Non-accelerated
      filer </FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&#9746;&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Smaller
      reporting company </FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&#9746;</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Emerging
      growth company </FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&#9746;</FONT></TD></TR>
    </TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">If an emerging
  growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any
  new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. &#9744;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <!-- Field: Page; Sequence: 1 -->
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>CALCULATION
  OF REGISTRATION FEE</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>&nbsp;</B></FONT></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%; font: 10pt Times New Roman, Times, Serif">
    <TR STYLE="vertical-align: bottom">
      <TD STYLE="border-bottom: Black 1.5pt solid; text-align: center"><P STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt">&nbsp;</P><P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left; margin-top: 0pt; margin-bottom: 0pt"><B>Title
  of Securities to be Registered</B></P></TD><TD STYLE="padding-bottom: 1.5pt; text-align: center; font-weight: bold">&nbsp;</TD>
      <TD COLSPAN="2" STYLE="border-bottom: Black 1.5pt solid; text-align: center; font-weight: bold">Amount to be Registered (1)</TD><TD STYLE="padding-bottom: 1.5pt; text-align: center; font-weight: bold">&nbsp;</TD><TD STYLE="padding-bottom: 1.5pt; text-align: center">&nbsp;</TD>
      <TD COLSPAN="2" STYLE="border-bottom: Black 1.5pt solid; text-align: center"><P STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><B>Proposed Maximum Offering </B></P> <P STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><B>Price per Share</B></P></TD><TD STYLE="padding-bottom: 1.5pt; text-align: center">&nbsp;</TD><TD STYLE="padding-bottom: 1.5pt; text-align: center; font-weight: bold">&nbsp;</TD>
      <TD COLSPAN="2" STYLE="border-bottom: Black 1.5pt solid; text-align: center; font-weight: bold">Proposed Maximum Aggregate Offering Price</TD><TD STYLE="padding-bottom: 1.5pt; text-align: center; font-weight: bold">&nbsp;</TD><TD STYLE="padding-bottom: 1.5pt; text-align: center; font-weight: bold">&nbsp;</TD>
      <TD COLSPAN="2" STYLE="border-bottom: Black 1.5pt solid; text-align: center; font-weight: bold">Amount of Registration Fee</TD><TD STYLE="padding-bottom: 1.5pt; text-align: center; font-weight: bold">&nbsp;</TD></TR>
    <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
      <TD STYLE="width: 52%; text-align: left">Common Stock</TD><TD STYLE="width: 1%">&nbsp;</TD>
      <TD STYLE="width: 1%; text-align: left">&nbsp;</TD><TD STYLE="width: 9%; text-align: right">4,200,000&nbsp;shares</TD><TD STYLE="width: 1%; text-align: left">&nbsp;</TD><TD STYLE="width: 1%">&nbsp;</TD>
      <TD STYLE="width: 1%; text-align: left">$</TD><TD STYLE="width: 9%; text-align: right">8.40</TD><TD STYLE="width: 1%; text-align: left">(2)</TD><TD STYLE="width: 1%">&nbsp;</TD>
      <TD STYLE="width: 1%; text-align: left">$</TD><TD STYLE="width: 9%; text-align: right">35,280,000</TD><TD STYLE="width: 1%; text-align: left">(2)</TD><TD STYLE="width: 1%">&nbsp;</TD>
      <TD STYLE="width: 1%; text-align: left">$</TD><TD STYLE="width: 9%; text-align: right">3,270.46</TD><TD STYLE="width: 1%; text-align: left">&nbsp;</TD></TR>
    </TABLE>
  
  
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.25in; text-align: justify; text-indent: -0.25in">&nbsp;</P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; width: 100%"><TR STYLE="vertical-align: top; text-align: justify">
  <TD STYLE="width: 0in"></TD><TD STYLE="width: 0.25in; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif">(1)</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">In
  addition, pursuant to Rule 416(c) under the Securities Act of 1933, as amended (the &ldquo;Securities Act&rdquo;), this Registration
  Statement includes an indeterminate number of additional shares which may be offered and sold as a result of anti-dilution provisions
  described in the above-referenced plan.</FONT></TD>
  </TR></TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.25in; text-indent: -0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
  <TD STYLE="font-family: Times New Roman, Times, Serif; width: 0"></TD><TD STYLE="font-family: Times New Roman, Times, Serif; width: 0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif">(2)</FONT></TD><TD STYLE="text-align: justify; font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">Estimated
                                              solely for the purpose of calculating the amount of the registration fee and calculated pursuant
                                              to Rule 457(h)(1) and Rule 457(c) under the Securities Act.</FONT></TD></TR></TABLE>
  
  <P STYLE="margin-top: 0; margin-bottom: 0">&nbsp;</P>
  
  <P STYLE="margin-top: 0; margin-bottom: 0"></P>
  
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  <P STYLE="margin-top: 0; margin-bottom: 0">&nbsp;&nbsp;</P>
  
  
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>&nbsp;</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>PART
  I</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>&nbsp;</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>INFORMATION
  REQUIRED IN THE SECTION 10(a) PROSPECTUS</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>&nbsp;</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>Item&nbsp;1.
  Plan Information</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 38.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 38.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">On
  November 4, 2021, TFF Pharmaceuticals, Inc. (the &ldquo;Company&rdquo;) adopted its 2021 Stock Incentive Plan (&ldquo;Plan&rdquo;). The
  maximum number of shares of common stock of the Company that are available for issuance under the Plan is 4,200,000 shares. This Registration
  Statement on Form S-8 is filed with the Securities and Exchange Commission (&ldquo;Commission&rdquo;) for the purposes of registering
  the 4,200,000 shares of the Company&rsquo;s common stock issuable under the Plan.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">The
  document(s) containing the information specified in Part I of Form S-8 will be sent or given to participants in the Plan as specified
  by Rule 428(b)(1) under the Securities Act of 1933, as amended (the &ldquo;Securities Act&rdquo;). Such documents are not being filed
  with the Commission, but constitute, along with the documents incorporated by reference into this Registration Statement, a prospectus
  that meets the requirements of Section&nbsp;10(a) of the Securities Act.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>&nbsp;</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>Item&nbsp;2.
  Registrant Information and Employee Plan Annual Information</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">The
  Company will furnish without charge to each person to whom the prospectus is delivered, upon the written or oral request of such person,
  a copy of any and all of the documents incorporated by reference in Item&nbsp;3 of Part II of this Registration Statement and incorporated
  by reference in the Section&nbsp;10(a) prospectus, other than exhibits to such documents (unless such exhibits are specifically incorporated
  by reference to the information that is incorporated). Written requests should be made to Investor Relations of TFF Pharmaceuticals,
  Inc. at 3801 S. Capital of Texas Hwy, Suite 330 Austin, Texas 78704; telephone number (737) 802-1973 or to the email address at investorinfo@tffpharma.com.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif"></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; text-transform: uppercase"><B>&nbsp;</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; text-transform: uppercase"><B>Part
  </B></FONT><B><FONT STYLE="font-family: Times New Roman, Times, Serif">II</FONT></B></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>INFORMATION
  REQUIRED</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>IN
  THE REGISTRATION STATEMENT</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>&nbsp;</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Item&nbsp;3.
  Incorporation of Certain Documents by Reference</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">The
  following documents filed by the Company with the Commission are incorporated by reference into this Registration Statement:</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif"></FONT></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
  <TD STYLE="width: 0.5in"></TD><TD STYLE="width: 0.25in">(a)</TD><TD STYLE="text-align: justify">The Company&rsquo;s Annual Report on <A HREF="http://www.sec.gov/Archives/edgar/data/1733413/000121390021014575/f10k2020_tffpharma.htm">Form 10-K</A> for the fiscal year ended December 31, 2020, which was
  filed on March&nbsp;10, 2021;</TD></TR><TR STYLE="vertical-align: top">
  <TD>&nbsp;</TD><TD>&nbsp;</TD><TD STYLE="text-align: justify">&nbsp;</TD></TR>
  
  <TR STYLE="vertical-align: top">
  <TD STYLE="width: 0.5in"></TD><TD STYLE="width: 0.25in">(b)</TD><TD STYLE="text-align: justify">The Company&rsquo;s Amendment No. 1 to Annual Report on <A HREF="http://www.sec.gov/Archives/edgar/data/1733413/000121390021023593/f10k2020a1_tffpharma.htm">Form 10-K</A> for the fiscal year ended December&nbsp;31,
  2020, which was filed on April 29, 2021;</TD></TR><TR STYLE="vertical-align: top">
  <TD>&nbsp;</TD><TD>&nbsp;</TD><TD STYLE="text-align: justify">&nbsp;</TD></TR>
  
  <TR STYLE="vertical-align: top">
  <TD STYLE="width: 0.5in"></TD><TD STYLE="width: 0.25in">(c)</TD><TD STYLE="text-align: justify">The Company&rsquo;s Quarterly Report on <A HREF="http://www.sec.gov/Archives/edgar/data/1733413/000121390021026067/f10q0321_tffpharma.htm">Form 10-Q</A> for the quarter ended March 31, 2021, which was filed
  on May 13, 2021;</TD></TR><TR STYLE="vertical-align: top">
  <TD>&nbsp;</TD><TD>&nbsp;</TD><TD STYLE="text-align: justify">&nbsp;</TD></TR>
  
  <TR STYLE="vertical-align: top">
  <TD STYLE="width: 0.5in"></TD><TD STYLE="width: 0.25in">(d)</TD><TD STYLE="text-align: justify">The Company&rsquo;s Quarterly Report on <A HREF="http://www.sec.gov/ix?doc=/Archives/edgar/data/1733413/000121390021042002/f10q0621_tffpharma.htm">Form 10-Q</A> for the quarter ended June 30, 2021, which was filed
  on August 12, 2021;</TD></TR><TR STYLE="vertical-align: top">
  <TD>&nbsp;</TD><TD>&nbsp;</TD><TD STYLE="text-align: justify">&nbsp;</TD></TR>
  
  <TR STYLE="vertical-align: top">
  <TD STYLE="width: 0.5in"></TD><TD STYLE="width: 0.25in">(e)</TD><TD STYLE="text-align: justify">The Company&rsquo;s Quarterly Report on <A HREF="http://www.sec.gov/ix?doc=/Archives/edgar/data/1733413/000121390021059329/f10q0921_tffpharma.htm">Form 10-Q</A> for the quarter ended September 30, 2021, which was
  filed on November 15, 2021</TD></TR><TR STYLE="vertical-align: top">
  <TD>&nbsp;</TD><TD>&nbsp;</TD><TD STYLE="text-align: justify">&nbsp;</TD></TR>
  
  <TR STYLE="vertical-align: top">
  <TD STYLE="width: 0.5in"></TD><TD STYLE="width: 0.25in">(f)</TD><TD STYLE="text-align: justify">The Company&rsquo;s Current Reports on Form
                                                                  8-K filed on <A HREF="http://www.sec.gov/Archives/edgar/data/1733413/000121390021017881/ea138463-8k_tffpharma.htm">March 26, 2021</A> and <A HREF="http://www.sec.gov/ix?doc=/Archives/edgar/data/1733413/000121390021058147/ea150362-8k_tffpharma.htm">November 10, 2021</A> (excluding any information furnished pursuant to Item 2.02 or Item 7.01 of
                                                                  such Current Report on Form 8-K, unless otherwise indicated therein);</TD></TR><TR STYLE="vertical-align: top">
  <TD>&nbsp;</TD><TD>&nbsp;</TD><TD STYLE="text-align: justify">&nbsp;</TD></TR>
  
  <TR STYLE="vertical-align: top">
  <TD STYLE="width: 0.5in"></TD><TD STYLE="width: 0.25in">(g)</TD><TD STYLE="text-align: justify">The description of the Company&rsquo;s common stock in its <A HREF="http://www.sec.gov/Archives/edgar/data/1733413/000121390019020831/f8a12b101519_tffpharma.htm">Form 8-A12B</A>, which was filed on October&nbsp;22,
  2019, and any amendments or reports filed for the purpose of updating this description; and</TD></TR><TR STYLE="vertical-align: top">
  <TD>&nbsp;</TD><TD>&nbsp;</TD><TD STYLE="text-align: justify">&nbsp;</TD></TR>
  
  <TR STYLE="vertical-align: top">
  <TD STYLE="width: 0.5in"></TD><TD STYLE="width: 0.25in">(h)</TD><TD STYLE="text-align: justify">All reports and other documents subsequently filed by the Company pursuant to Sections 13(a), 13(c), 14
  and 15(d) of the Exchange Act prior to the filing of a post-effective amendment which indicates that all securities offered have been
  sold or which deregisters all securities then remaining unsold.</TD></TR></TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif"></FONT></P>
  
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif"></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: left"><FONT STYLE="font-size: 10pt"><B>Item&nbsp;4.
  Description of Securities</B></FONT></P>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 24.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">Not
  applicable.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>&nbsp;</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Item
  5. Interests of Named Experts and Counsel</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
  validity of the issuance of the shares of the Company&rsquo;s common stock offered by this Registration Statement has been passed upon
  by Greenberg Traurig, LLP, Irvine, California</FONT><FONT STYLE="font-family: Times New Roman, Times, Serif">.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>&nbsp;</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Item
  6. Indemnification of Directors and Officers</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">The
  following summary is qualified in its entirety by reference to the complete text of any statutes referred to below and the second amended
  and restated certificate of incorporation of TFF Pharmaceuticals, Inc., a Delaware corporation.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Section
  145 of the General Corporation Law of the State of Delaware (the &ldquo;DGCL&rdquo;) permits a Delaware corporation to indemnify any
  person who was or is a party or is threatened to be made a party to any threatened, pending or completed action, suit or proceeding,
  whether civil, criminal, administrative or investigative (other than an action by or in the right of the corporation) by reason of the
  fact that the person is or was a director, officer, employee or agent of the corporation, or is or was serving at the request of the
  corporation as a director, officer, employee or agent of another corporation, partnership, joint venture, trust or other enterprise,
  against expenses (including attorneys&rsquo; fees), judgments, fines and amounts paid in settlement actually and reasonably incurred
  by the person in connection with such action, suit or proceeding if the person acted in good faith and in a manner the person reasonably
  believed to be in or not opposed to the best interests of the corporation, and, with respect to any criminal action or proceeding, had
  no reasonable cause to believe the person&rsquo;s conduct was unlawful.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">In
  the case of an action by or in the right of the corporation, Section 145 of the DGCL permits a Delaware corporation to indemnify any
  person who was or is a party or is threatened to be made a party to any threatened, pending or completed action or suit by reason of
  the fact that the person is or was a director, officer, employee or agent of the corporation, or is or was serving at the request of
  the corporation as a director, officer, employee or agent of another corporation, partnership, joint venture, trust or other enterprise,
  against expenses (including attorneys&rsquo; fees) actually and reasonably incurred by the person in connection with such action, suit
  or proceeding if the person acted in good faith and in a manner the person reasonably believed to be in or not opposed to the best interests
  of the corporation and except that no indemnification shall be made in respect of any claim, issue or matter as to which such person
  shall have been adjudged to be liable to the corporation unless and only to the extent that the Court of Chancery or the court in which
  such action or suit was brought shall determine upon application that, despite the adjudication of liability but in view of all the circumstances
  of the case, such person is fairly and reasonably entitled to indemnity for such expenses that the Court of Chancery or such other court
  shall deem proper.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Section
  145 of the DGCL also permits a Delaware corporation to purchase and maintain insurance on behalf of any person who is or was a director,
  officer, employee or agent of the corporation, or is or was serving at the request of the corporation as a director, officer, employee
  or agent of another corporation, partnership, joint venture, trust or other enterprise against any liability asserted against such person
  and incurred by such person in any such capacity, or arising out of such person&rsquo;s status as such, whether or not the corporation
  would have the power to indemnify such person against such liability under Section 145 of the DGCL.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Article
  Sixth of our Second Amended and Restated Certificate of Incorporation states that to the fullest extent permitted by the DGCL our directors
  shall not be personally liable to us or to our stockholders for monetary damages for breach of fiduciary duty as a director. If the DGCL
  is amended after the date hereof to authorize corporate action further eliminating or limiting the personal liability of directors, then
  the liability of our directors shall be eliminated or limited to the fullest extent permitted by the DGCL, as so amended.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <!-- Field: Page; Sequence: 5; Value: 1 -->
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif"></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Article
  Seventh of our Second Amended and Restated Certificate of Incorporation provides that we shall, to the maximum extent and in the manner
  permitted by the DGCL, indemnify each of our directors, officers and all other persons we have the power to indemnify under Section 145
  of the DGCL against expenses (including attorneys&rsquo; fees), judgments, fines, settlements and other amounts actually and reasonably
  incurred in connection with any proceeding, arising by reason of the fact that such person is or was a director, officer, employee or
  agent of the Company.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">As
  permitted by the DGCL, we have entered into indemnification agreements with each of our directors and executive officers that require
  us to indemnify such persons against various actions including, but not limited to, third-party actions where such director or executive
  officer, by reason of his or her corporate status, is a party or is threatened to be made a party to an action, or by reason of anything
  done or not done by such director in any such capacity. We intend to indemnify directors and executive officers against all costs, judgments,
  penalties, fines, liabilities, amounts paid in settlement by or on behalf such directors or executive officers and for any expenses actually
  and reasonably incurred by such directors or executive officers in connection with such action, if such directors or executive officers
  acted in good faith and in a manner they reasonably believed to be in or not opposed to the best interests of the Company, and with respect
  to any criminal proceeding, had no reasonable cause to believe their conduct was unlawful. We also intend to advance to our directors
  and executive officers expenses (including attorney&rsquo;s fees) incurred by such directors and executive officers in advance of the
  final disposition of any action after the receipt by us of a statement or statements from directors or executive officers requesting
  such payment or payments from time to time, provided that such statement or statements are accompanied by an undertaking, by or on behalf
  of such directors or executive officers, to repay such amount if it shall ultimately be determined that they are not entitled to be indemnified
  against such expenses by us.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">The
  indemnification agreements also set forth certain procedures that will apply in the event of a claim for indemnification or advancement
  of expenses, including, among others, provisions about providing notice to us of any action in connection with which a director or executive
  officer seeks indemnification or advancement of expenses from us and provisions concerning the determination of entitlement to indemnification
  or advancement of expenses.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Insofar
  as indemnification for liabilities arising under the Securities Act, may be permitted to our directors, officers or persons controlling
  us pursuant to the provisions contained in our Amended and Restated Certificate of Incorporation, Bylaws, the DGCL or otherwise, we have
  been informed that, in the opinion of the SEC, such indemnification is against public policy as expressed in the Securities Act and is
  therefore unenforceable. If a claim for indemnification against such liabilities, other than the payment by us of expenses incurred or
  paid by one of our directors, officers or controlling persons in the successful defense of any action, suit, or proceeding, is asserted
  by such director, officer or controlling person, we will, unless in the opinion of our counsel the matter has been settled by controlling
  precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by us is against public policy as
  expressed in the Securities Act and will be governed by the final adjudication of this issue.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>&nbsp;</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Item
  7. Exemption from Registration Claimed</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 24.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Not
  applicable.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>&nbsp;</B></FONT></P>
  
  
  <!-- Field: Page; Sequence: 6; Value: 1 -->
      <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1.5pt solid"><P STYLE="text-align: center; margin-top: 0pt; margin-bottom: 0pt"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->4<!-- Field: /Sequence --></P></DIV>
      <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
      <!-- Field: /Page -->
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>Item
  8. Exhibits.</B></FONT></P>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
    <TR STYLE="font-family: Times New Roman, Times, Serif">
      <TD STYLE="text-indent: 0; border-bottom: Black 1.5pt solid; text-align: left; padding-top: 0; font-family: Times New Roman, Times, Serif; vertical-align: bottom; padding-right: 0; padding-left: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>Exhibit
      No.</B></FONT></TD>
      <TD STYLE="padding-bottom: 1.5pt; font-family: Times New Roman, Times, Serif; vertical-align: top; padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
      <TD STYLE="padding-top: 0; border-bottom: Black 1.5pt solid; font-family: Times New Roman, Times, Serif; vertical-align: bottom; padding-right: 0; padding-left: 0; layout-grid-mode: line; text-align: center"><B>Description
      of Exhibits</B></TD>
      <TD STYLE="padding-bottom: 1.5pt; font-family: Times New Roman, Times, Serif; vertical-align: top; padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
      <TD STYLE="padding-bottom: 1.5pt; font-family: Times New Roman, Times, Serif; vertical-align: top; padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif">
      <TD STYLE="padding-top: 0; text-indent: 0; border-bottom: Black 1.5pt solid; text-align: left; font-family: Times New Roman, Times, Serif; vertical-align: bottom; width: 10%; padding-right: 0; padding-left: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>Exhibit
  No.</B></FONT></P></TD>
      <TD STYLE="padding-bottom: 1.5pt; font-family: Times New Roman, Times, Serif; vertical-align: top; width: 2%; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding-top: 0; border-bottom: Black 1.5pt solid; font-family: Times New Roman, Times, Serif; vertical-align: bottom; width: 50%; padding-right: 0; padding-left: 0; layout-grid-mode: line; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Description</B></FONT></TD>
      <TD STYLE="padding-bottom: 1.5pt; font-family: Times New Roman, Times, Serif; vertical-align: top; width: 2%; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="border-bottom: Black 1.5pt solid; font-family: Times New Roman, Times, Serif; vertical-align: top; width: 36%; padding-right: 5.4pt; padding-left: 5.4pt"><P STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>Method
  of Filing</B></FONT></P></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="padding-top: 0; font-family: Times New Roman, Times, Serif; padding-right: 0; padding-left: 0; text-align: left; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding-top: 0; font-family: Times New Roman, Times, Serif; padding-right: 0; padding-left: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top; background-color: rgb(204,238,255)">
      <TD STYLE="padding-top: 0; font-family: Times New Roman, Times, Serif; padding-right: 0; padding-left: 0; text-align: left; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.1</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding-top: 0; font-family: Times New Roman, Times, Serif; padding-right: 0; padding-left: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><A HREF="ea152968ex5-1_tffpharma.htm">Opinion and Consent of Greenberg Traurig, LLP</A></FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Filed
      electronically herewith</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top; background-color: White">
      <TD STYLE="padding-top: 0; font-family: Times New Roman, Times, Serif; padding-right: 0; padding-left: 0; text-align: left; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding-top: 0; font-family: Times New Roman, Times, Serif; padding-right: 0; padding-left: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top; background-color: rgb(204,238,255)">
      <TD STYLE="padding-top: 0; font-family: Times New Roman, Times, Serif; padding-right: 0; padding-left: 0; text-align: left; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">10.1</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding-top: 0; font-family: Times New Roman, Times, Serif; padding-right: 0; padding-left: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1733413/000121390021049574/def14a0921_tffpharma.htm">TFF Pharmaceuticals, Inc. 2021 Stock Incentive Plan</A></FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Incorporated
      by reference to Appendix A of Registrant&rsquo;s Proxy Statement filed on September 23, 2021 </FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top; background-color: White">
      <TD STYLE="padding-top: 0; font-family: Times New Roman, Times, Serif; padding-right: 0; padding-left: 0; text-align: left; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding-top: 0; font-family: Times New Roman, Times, Serif; padding-right: 0; padding-left: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top; background-color: rgb(204,238,255)">
      <TD STYLE="padding-top: 0; font-family: Times New Roman, Times, Serif; padding-right: 0; padding-left: 0; text-align: left; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">23.1</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding-top: 0; font-family: Times New Roman, Times, Serif; padding-right: 0; padding-left: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><A HREF="ea152968ex23-1_tffpharma.htm">Consent of Marcum LLP</A></FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Filed
      electronically herewith</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top; background-color: White">
      <TD STYLE="padding-top: 0; font-family: Times New Roman, Times, Serif; padding-right: 0; padding-left: 0; text-align: left; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding-top: 0; font-family: Times New Roman, Times, Serif; padding-right: 0; padding-left: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top; background-color: rgb(204,238,255)">
      <TD STYLE="padding-top: 0; font-family: Times New Roman, Times, Serif; padding-right: 0; padding-left: 0; text-align: left; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">23.4</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding-top: 0; font-family: Times New Roman, Times, Serif; padding-right: 0; padding-left: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><A HREF="ea152968ex5-1_tffpharma.htm">Consent of Greenberg Traurig, LLP</A></FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Included
      in Exhibit 5.1</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top; background-color: White">
      <TD STYLE="padding-top: 0; font-family: Times New Roman, Times, Serif; padding-right: 0; padding-left: 0; text-align: left; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding-top: 0; font-family: Times New Roman, Times, Serif; padding-right: 0; padding-left: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top; background-color: rgb(204,238,255)">
      <TD STYLE="padding-top: 0; font-family: Times New Roman, Times, Serif; padding-right: 0; padding-left: 0; text-align: left; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">24.1</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding-top: 0; font-family: Times New Roman, Times, Serif; padding-right: 0; padding-left: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><A HREF="#a_002">Power of Attorney</A></FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-right: 5.4pt; padding-left: 5.4pt; layout-grid-mode: line"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Included
      on the signature page to this registration statement</FONT></TD></TR>
    </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>Item
  9. Undertakings.</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; width: 100%"><TR STYLE="vertical-align: top; text-align: justify">
  <TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif">(a)</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">The
  undersigned registrant hereby undertakes:</FONT></TD>
  </TR></TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 1.25in; text-align: justify; text-indent: -0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; width: 100%"><TR STYLE="vertical-align: top; text-align: justify">
  <TD STYLE="width: 0.5in"></TD><TD STYLE="width: 0.25in; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif">(1)</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">To
  file, during any period in which offers or sales are being made, a post-effective amendment to this registration statement:</FONT></TD>
  </TR></TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 1.75in; text-align: justify; text-indent: -0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; width: 100%"><TR STYLE="vertical-align: top; text-align: justify">
  <TD STYLE="width: 0.75in"></TD><TD STYLE="width: 0.25in; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif">(i)</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">To
  include any prospectus required by Section 10(a)(3) of the Securities Act of 1933, as amended (the &ldquo;Securities Act&rdquo;).</FONT></TD>
  </TR></TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 1.75in; text-align: justify; text-indent: -0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; width: 100%"><TR STYLE="vertical-align: top; text-align: justify">
  <TD STYLE="width: 0.75in"></TD><TD STYLE="width: 0.25in; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif">(ii)</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">To
  reflect in the prospectus any facts or events arising after the effective date of the registration statement (or the most recent post-effective
  amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the registration
  statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities
  offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range
  may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) under the Securities Act if, in the aggregate,
  the changes in volume and price represent no more than a 20% change in the maximum aggregate offering price set forth in the &ldquo;Calculation
  of Registration Fee&rdquo; table in the effective registration statement.</FONT></TD>
  </TR></TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 1.75in; text-align: justify; text-indent: -0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; width: 100%"><TR STYLE="vertical-align: top; text-align: justify">
  <TD STYLE="width: 0.75in"></TD><TD STYLE="width: 0.25in; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif">(iii)</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">To
  include any material information with respect to the plan of distribution not previously disclosed in the registration statement or any
  material change to such information in the registration statement.</FONT></TD>
  </TR></TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 1.25in; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.75in; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">Provided,
  however, that paragraphs (a)(1)(i) and (a)(1)(ii) do not apply if the information required to be included in a post-effective amendment
  by those paragraphs is contained in periodic reports filed with or furnished to the Commission by the registrant pursuant to Section
  13 or section 15(d) of the Exchange Act that are incorporated by reference in the registration statement.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.75in; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.75in; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif"></FONT></P>
  
  <!-- Field: Page; Sequence: 7; Value: 1 -->
      <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1.5pt solid"><P STYLE="text-align: center; margin-top: 0pt; margin-bottom: 0pt"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->5<!-- Field: /Sequence --></P></DIV>
      <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
      <!-- Field: /Page -->
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.75in; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; width: 100%"><TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
  <TD STYLE="font-family: Times New Roman, Times, Serif; width: 0.5in"></TD><TD STYLE="font-family: Times New Roman, Times, Serif; width: 0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif">(2)</FONT></TD><TD STYLE="font-family: Times New Roman, Times, Serif; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">That,
                                              for the purpose of determining any liability under the Securities Act, each such post-effective
                                              amendment shall be deemed to be a new registration statement relating to the securities offered
                                              therein, and the offering of such securities at that time shall be deemed to be the initial
                                              bona fide offering thereof.</FONT></TD></TR></TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 1.25in; text-align: justify; text-indent: -0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; width: 100%"><TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
  <TD STYLE="font-family: Times New Roman, Times, Serif; width: 0.5in"></TD><TD STYLE="font-family: Times New Roman, Times, Serif; width: 0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif">(3)</FONT></TD><TD STYLE="font-family: Times New Roman, Times, Serif; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">To
                                              remove from registration by means of a post-effective amendment any of the securities being
                                              registered which remain unsold at the termination of the offering.</FONT></TD></TR></TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.75in; text-align: justify; text-indent: -0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; width: 100%"><TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
  <TD STYLE="font-family: Times New Roman, Times, Serif; width: 0.25in"></TD><TD STYLE="font-family: Times New Roman, Times, Serif; width: 0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif">(b)</FONT></TD><TD STYLE="font-family: Times New Roman, Times, Serif; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">The
                                              undersigned registrant hereby undertakes that, for purposes of determining any liability
                                              under the Securities Act, each filing of the registrant&rsquo;s annual report pursuant to
                                              Section 13(a) or Section 15(d) of the Securities Exchange Act of 1934, as amended (the &ldquo;Exchange
                                              Act&rdquo;) (and where applicable, each filing of an employee benefit plan&rsquo;s annual
                                              report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in
                                              the registration statement shall be deemed to be a new registration statement relating to
                                              the securities offered therein, and the offering of such securities at that time shall be
                                              deemed to be the initial bona fide offering thereof.</FONT></TD></TR></TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.75in; text-align: justify; text-indent: -0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; width: 100%"><TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
  <TD STYLE="font-family: Times New Roman, Times, Serif; width: 0.25in"></TD><TD STYLE="font-family: Times New Roman, Times, Serif; width: 0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif">(c)</FONT></TD><TD STYLE="font-family: Times New Roman, Times, Serif; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">Insofar
                                              as indemnification for liabilities arising under the Securities Act may be permitted to directors,
                                              officers and controlling persons of the registrant pursuant to the foregoing provisions,
                                              or otherwise, the registrant has been advised that in the opinion of the Commission such
                                              indemnification is against public policy as expressed in the Securities Act, and is therefore,
                                              unenforceable. In the event that a claim for indemnification against such liabilities (other
                                              than the payment by the registrant in the successful defense of any action, suit or proceeding)
                                              is asserted by such director, officer or controlling person in connection with the securities
                                              being registered, the registrant will, unless in the opinion of its counsel the matter has
                                              been settled by controlling precedent, submit to a court of appropriate jurisdiction the
                                              question whether such indemnification by it is against public policy as expressed in the
                                              Securities Act and will be governed by the final adjudication of such issue.</FONT></TD></TR></TABLE>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  
  <!-- Field: Page; Sequence: 8; Value: 1 -->
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      <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><A NAME="a_002"></A><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>SIGNATURES</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Pursuant
  to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all
  of the requirements of filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned,
  thereunto duly authorized, in the city of Austin, Texas on December 27, 2021.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif"></FONT></P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-align: justify; text-indent: 0">&nbsp;</TD>
      <TD COLSPAN="2" STYLE="padding: 0; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; text-transform: uppercase">TFF PHARMACEUTICALS, INC.</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; width: 40%; text-align: justify; text-indent: 0">&nbsp;</TD>
      <TD STYLE="padding: 0; width: 4%; text-align: justify; text-indent: 0">&nbsp;</TD>
      <TD STYLE="padding: 0; width: 36%; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0 0 1.5pt; text-align: justify; text-indent: 0">&nbsp;</TD>
      <TD STYLE="padding-top: 0; padding-right: 0; padding-left: 0; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">By:</FONT></TD>
      <TD STYLE="border-bottom: Black 1.5pt solid; padding-top: 0; padding-right: 0; padding-left: 0; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>/s/ Glenn Mattes</I></FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-align: justify; text-indent: 0">&nbsp;</TD>
      <TD STYLE="padding: 0; text-align: justify; text-indent: 0">&nbsp;</TD>
      <TD STYLE="padding: 0; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Glenn Mattes</FONT></TD></TR>
    <TR STYLE="vertical-align: top">
      <TD STYLE="padding: 0; text-indent: 0">&nbsp;</TD>
      <TD STYLE="padding: 0; text-indent: 0">&nbsp;</TD>
      <TD STYLE="padding: 0; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Chief Executive Officer</FONT></TD></TR>
    </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>POWER
  OF ATTORNEY</B></FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Each
  person whose signature appears below hereby constitutes and appoints Glenn Mattes and Kirk Coleman, and each of them, as such person&rsquo;s
  true and lawful attorney-in-fact and agent, each with full powers of substitution and re-substitution, for such person and in such person&rsquo;s
  name, place and stead, in any and all capacities, to sign any or all amendments (including post effective amendments) to this Registration
  Statement, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange
  Commission, granting unto said attorney-in-fact and agent full power and authority to do and perform each and every act and thing requisite
  or necessary to be done in and about the premises, as fully to all intents and purposes as such person might or could do in person, hereby
  ratifying and confirming all that said attorney-in-fact and agent or his or her substitute or substitutes, may lawfully do or cause to
  be done by virtue thereof.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif">Pursuant
  to the requirements of the Securities Act of 1933, this Registration Statement has been signed on December 27, 2021 by the following
  persons in the capacities indicated.</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif"></FONT></P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding-top: 0; padding-right: 0; padding-left: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>Signature&#9;</B></FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-bottom: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="border-bottom: Black 1.5pt solid; padding-top: 0; padding-right: 0; padding-left: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>Title</B></FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding-top: 0; padding-right: 0; padding-left: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"><I>/s/
      Glenn Mattes</I></FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-bottom: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0 0 1.5pt; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">President,
      Chief Executive Officer and Director&nbsp;</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; width: 40%; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Glenn
      Mattes</FONT></P></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; width: 2%"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; width: 58%; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">(Principal
      Executive Officer)</FONT><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"></P></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding-top: 0; padding-right: 0; padding-left: 0; font-family: Times New Roman, Times, Serif; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"><I>/s/
      Kirk Coleman</I></FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-bottom: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0 0 1.5pt; font-family: Times New Roman, Times, Serif; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Chief
      Financial Officer (Principal Financial and Accounting Officer)</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Kirk
      Coleman</FONT></P></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"></P></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding-top: 0; padding-right: 0; padding-left: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"><I>/s/
      Aaron Fletcher, Ph.D.</I></FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-bottom: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0 0 1.5pt; font-family: Times New Roman, Times, Serif; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Chairman
      of the Board</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Aaron
      Fletcher, Ph.D.</FONT></P></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"></P></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding-top: 0; padding-right: 0; padding-left: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"><I>/s/
      Brian Windsor, Ph.D</I></FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-bottom: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0 0 1.5pt; font-family: Times New Roman, Times, Serif; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Director</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Brian
      Windsor, Ph.D.</FONT></P></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding-top: 0; padding-right: 0; padding-left: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"><I>/s/
      Robert S. Mills, Jr.</I></FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-bottom: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0 0 1.5pt; font-family: Times New Roman, Times, Serif; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Director</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Robert
      S. Mills, Jr.</FONT></P></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"></P></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding-top: 0; padding-right: 0; padding-left: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"><I>/s/
      Stephen C. Rocamboli</I></FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-bottom: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0 0 1.5pt; font-family: Times New Roman, Times, Serif; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Director</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Stephen
      C. Rocamboli</FONT></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"></P></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding-top: 0; padding-right: 0; padding-left: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"><I>/s/
      Harlan Weisman, M.D.</I></FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-bottom: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0 0 1.5pt; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Director</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Harlan
      Weisman, M.D.</FONT></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"></P></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding-top: 0; padding-right: 0; padding-left: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"><I>/s/
      Randy Thurman</I></FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-bottom: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0 0 1.5pt; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Director</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Randy
      Thurman</FONT></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"></P></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding-top: 0; padding-right: 0; padding-left: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"><I>/s/
      Malcolm Fairbairn</I></FONT></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif; padding-bottom: 1.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0 0 1.5pt; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Director</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Malcolm
      Fairbairn</FONT></P></TD>
      <TD STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"></P></TD></TR>
    </TABLE>
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B></B></FONT></P>
  
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      <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
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  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>
  
  <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>INDEX
  TO EXHIBITS</B></FONT></P>
  
  <P STYLE="text-indent: 0.25in; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  <TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="border-bottom: Black 1.5pt solid; padding-top: 0; padding-right: 0; padding-left: 0; font-family: Times New Roman, Times, Serif; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>No.</B></FONT></TD>
      <TD STYLE="padding-bottom: 1.5pt"><B>&nbsp;</B></TD>
      <TD STYLE="text-align: center; border-bottom: Black 1.5pt solid; padding-top: 0; padding-right: 0; padding-left: 0; font-family: Times New Roman, Times, Serif"><B>Item</B></TD>
      <TD STYLE="padding-bottom: 1.5pt"><B>&nbsp;</B></TD>
      <TD STYLE="text-align: center; border-bottom: Black 1.5pt solid; padding-top: 0; padding-right: 0; padding-left: 0; font-family: Times New Roman, Times, Serif"><B>Method of Filing</B></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-align: justify; text-indent: 0">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0">&nbsp;</TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top; background-color: rgb(204,238,255)">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; width: 5%; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.1</FONT></TD>
      <TD STYLE="width: 2%">&nbsp;</TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; width: 50%; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><A HREF="ea152968ex5-1_tffpharma.htm">Opinion and Consent of Greenberg Traurig, LLP</A></FONT></TD>
      <TD STYLE="width: 2%">&nbsp;</TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; width: 41%; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Filed
      electronically herewith</FONT></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top; background-color: White">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-align: justify; text-indent: 0">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0">&nbsp;</TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top; background-color: rgb(204,238,255)">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">23.1</FONT></TD>
      <TD>&nbsp;</TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><A HREF="ea152968ex23-1_tffpharma.htm">Consent of Marcum LLP</A></FONT></TD>
      <TD>&nbsp;</TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Filed
      electronically herewith</FONT></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top; background-color: White">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-align: justify; text-indent: 0">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0">&nbsp;</TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top; background-color: rgb(204,238,255)">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">23.4</FONT></TD>
      <TD>&nbsp;</TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"><A HREF="ea152968ex5-1_tffpharma.htm">Consent of Greenberg Traurig, LLP</A></FONT></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"></FONT></P></TD>
      <TD>&nbsp;</TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Included
      in Exhibit 5.1</FONT></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top; background-color: White">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-align: justify; text-indent: 0">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0">&nbsp;</TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top; background-color: rgb(204,238,255)">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">24.1</FONT></TD>
      <TD>&nbsp;</TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><A HREF="#a_002">Power of Attorney</A></FONT></TD>
      <TD>&nbsp;</TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Included
      on the signature page to this registration statement</FONT></P>
      <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif"></FONT></P></TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top; background-color: White">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-align: justify; text-indent: 0">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0">&nbsp;</TD>
      <TD>&nbsp;</TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0">&nbsp;</TD></TR>
    <TR STYLE="font-family: Times New Roman, Times, Serif; vertical-align: top; background-color: rgb(204,238,255)">
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-align: justify; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">10.1</FONT></TD>
      <TD>&nbsp;</TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><A HREF="http://www.sec.gov/Archives/edgar/data/1733413/000121390021049574/def14a0921_tffpharma.htm">TFF Pharmaceuticals, Inc. 2021 Stock Incentive Plan</A></FONT></TD>
      <TD>&nbsp;</TD>
      <TD STYLE="padding: 0; font-family: Times New Roman, Times, Serif; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Incorporated
      by reference to Appendix A of Registrant&rsquo;s Proxy Statement filed on September 23, 2021 </FONT></TD></TR>
    </TABLE>
  
  <P STYLE="font-family: Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0">&nbsp;</P>
  
  <P STYLE="text-align: center; font-family: Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0">&nbsp;</P>
  
  <P STYLE="text-align: center; font-family: Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0">8</P>
  
  <P STYLE="font-family: Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"></P>
  
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  <P STYLE="font-family: Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>
  
  </BODY>
  </HTML>
metadata_documents: [{"type": "S-8", "sequence": "1", "filename": "ea152968-s8_tffpharma.htm", "description": "REGISTRATION STATEMENT", "secsgml_size_bytes": 113310}]
metadata_filer: {"company-data": {"conformed-name": "TFF Pharmaceuticals, Inc.", "cik": "0001733413", "assigned-sic": "2834", "irs-number": "824344737", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-261896", "film-number": "211520413"}, "business-address": {"street1": "2600 VIA FORTUNA, SUITE 360", "city": "AUSTIN", "state": "TX", "zip": "78746", "phone": "737-802-1973"}, "mail-address": {"street1": "2600 VIA FORTUNA, SUITE 360", "city": "AUSTIN", "state": "TX", "zip": "78746"}}
text: As
  filed with the Securities and Exchange Commission on December 27, 2021
  Registration
  No. ______
  UNITED
  STATES
  SECURITIES
  AND EXCHANGE COMMISSION
  WASHINGTON,
  D.C. 20549
  _______________________
  FORM
  S-8
  REGISTRATION
  STATEMENT
  UNDER
  THE SECURITIES ACT OF 1933
  TFF
  Pharmaceuticals, Inc.
  (Exact
  name of registrant as specified in its charter)
  Delaware
  82-4344737
  (State
      or other jurisdiction of
  incorporation
      or organization)
  (I.R.S.
      Employer
  Identification
      No.)
  3801
      S. Capital of Texas Hwy, Suite 330
  Austin, Texas
  78704
  (Address
      of Principal Executive Offices)
  (Zip
      Code)
  _______________________
  2021
  Stock Incentive Plan
  (Full
  title of the plan)
  _______________________
  Glenn
  Mattes
  Chief Executive Officer
  3801 S. Capital of Texas Hwy, Suite 330
  Austin, Texas 78704
  (Name and address of agent for service)
  (737)
  802-1973
  (Telephone
  number, including area code, of agent for service)
  Copy
  to:
  Daniel
  K. Donahue
  Greenberg
  Traurig, LLP
  18565
  Jamboree Road, Suite 500
  Irvine,
  California 92612
  (949)
  732-6500
  Indicate
  by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting
  company or an emerging growth company. See the definitions of "large accelerated filer," "accelerated filer,"
  "smaller reporting company," and "emerging growth company" in Rule 12b-2 of the Exchange Act.
  Large
      accelerated filer
  ☐
  Accelerated
      filer
  ☐
  Non-accelerated
      filer
  ☒
  Smaller
      reporting company
  ☒
  Emerging
      growth company
  ☒
  If an emerging
  growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any
  new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐
  CALCULATION
  OF REGISTRATION FEE
  Title
  of Securities to be Registered
  Amount to be Registered (1)
  Proposed Maximum Offering
  Price per Share
  Proposed Maximum Aggregate Offering Price
  Amount of Registration Fee
  Common Stock
  4,200,000 shares
  $
  8.40
  (2)
  $
  35,280,000
  (2)
  $
  3,270.46
  (1)
  In
  addition, pursuant to Rule 416(c) under the Securities Act of 1933, as amended (the "Securities Act"), this Registration
  Statement includes an indeterminate number of additional shares which may be offered and sold as a result of anti-dilution provisions
  described in the above-referenced plan.
  (2)
  Estimated
                                              solely for the purpose of calculating the amount of the registration fee and calculated pursuant
                                              to Rule 457(h)(1) and Rule 457(c) under the Securities Act.
  PART
  I
  INFORMATION
  REQUIRED IN THE SECTION 10(a) PROSPECTUS
  Item 1.
  Plan Information
  On
  November 4, 2021, TFF Pharmaceuticals, Inc. (the "Company") adopted its 2021 Stock Incentive Plan ("Plan"). The
  maximum number of shares of common stock of the Company that are available for issuance under the Plan is 4,200,000 shares. This Registration
  Statement on Form S-8 is filed with the Securities and Exchange Commission ("Commission") for the purposes of registering
  the 4,200,000 shares of the Company's common stock issuable under the Plan.
  The
  document(s) containing the information specified in Part I of Form S-8 will be sent or given to participants in the Plan as specified
  by Rule 428(b)(1) under the Securities Act of 1933, as amended (the "Securities Act"). Such documents are not being filed
  with the Commission, but constitute, along with the documents incorporated by reference into this Registration Statement, a prospectus
  that meets the requirements of Section 10(a) of the Securities Act.
  Item 2.
  Registrant Information and Employee Plan Annual Information
  The
  Company will furnish without charge to each person to whom the prospectus is delivered, upon the written or oral request of such person,
  a copy of any and all of the documents incorporated by reference in Item 3 of Part II of this Registration Statement and incorporated
  by reference in the Section 10(a) prospectus, other than exhibits to such documents (unless such exhibits are specifically incorporated
  by reference to the information that is incorporated). Written requests should be made to Investor Relations of TFF Pharmaceuticals,
  Inc. at 3801 S. Capital of Texas Hwy, Suite 330 Austin, Texas 78704; telephone number (737) 802-1973 or to the email address at investorinfo@tffpharma.com.
  1
  Part
  II
  INFORMATION
  REQUIRED
  IN
  THE REGISTRATION STATEMENT
  Item 3.
  Incorporation of Certain Documents by Reference
  The
  following documents filed by the Company with the Commission are incorporated by reference into this Registration Statement:
  (a)
  The Company's Annual Report on
  Form 10-K
  for the fiscal year ended December 31, 2020, which was
  filed on March 10, 2021;
  (b)
  The Company's Amendment No. 1 to Annual Report on
  Form 10-K
  for the fiscal year ended December 31,
  2020, which was filed on April 29, 2021;
  (c)
  The Company's Quarterly Report on
  Form 10-Q
  for the quarter ended March 31, 2021, which was filed
  on May 13, 2021;
  (d)
  The Company's Quarterly Report on
  Form 10-Q
  for the quarter ended June 30, 2021, which was filed
  on August 12, 2021;
  (e)
  The Company's Quarterly Report on
  Form 10-Q
  for the quarter ended September 30, 2021, which was
  filed on November 15, 2021
  (f)
  The Company's Current Reports on Form
                                                                  8-K filed on
  March 26, 2021
  and
  November 10, 2021
  (excluding any information furnished pursuant to Item 2.02 or Item 7.01 of
                                                                  such Current Report on Form 8-K, unless otherwise indicated therein);
  (g)
  The description of the Company's common stock in its
  Form 8-A12B
  , which was filed on October 22,
  2019, and any amendments or reports filed for the purpose of updating this description; and
  (h)
  All reports and other documents subsequently filed by the Company pursuant to Sections 13(a), 13(c), 14
  and 15(d) of the Exchange Act prior to the filing of a post-effective amendment which indicates that all securities offered have been
  sold or which deregisters all securities then remaining unsold.
  2
  Item 4.
  Description of Securities
  Not
  applicable.
  Item
  5. Interests of Named Experts and Counsel
  The
  validity of the issuance of the shares of the Company's common stock offered by this Registration Statement has been passed upon
  by Greenberg Traurig, LLP, Irvine, California
  .
  Item
  6. Indemnification of Directors and Officers
  The
  following summary is qualified in its entirety by reference to the complete text of any statutes referred to below and the second amended
  and restated certificate of incorporation of TFF Pharmaceuticals, Inc., a Delaware corporation.
  Section
  145 of the General Corporation Law of the State of Delaware (the "DGCL") permits a Delaware corporation to indemnify any
  person who was or is a party or is threatened to be made a party to any threatened, pending or completed action, suit or proceeding,
  whether civil, criminal, administrative or investigative (other than an action by or in the right of the corporation) by reason of the
  fact that the person is or was a director, officer, employee or agent of the corporation, or is or was serving at the request of the
  corporation as a director, officer, employee or agent of another corporation, partnership, joint venture, trust or other enterprise,
  against expenses (including attorneys' fees), judgments, fines and amounts paid in settlement actually and reasonably incurred
  by the person in connection with such action, suit or proceeding if the person acted in good faith and in a manner the person reasonably
  believed to be in or not opposed to the best interests of the corporation, and, with respect to any criminal action or proceeding, had
  no reasonable cause to believe the person's conduct was unlawful.
  In
  the case of an action by or in the right of the corporation, Section 145 of the DGCL permits a Delaware corporation to indemnify any
  person who was or is a party or is threatened to be made a party to any threatened, pending or completed action or suit by reason of
  the fact that the person is or was a director, officer, employee or agent of the corporation, or is or was serving at the request of
  the corporation as a director, officer, employee or agent of another corporation, partnership, joint venture, trust or other enterprise,
  against expenses (including attorneys' fees) actually and reasonably incurred by the person in connection with such action, suit
  or proceeding if the person acted in good faith and in a manner the person reasonably believed to be in or not opposed to the best interests
  of the corporation and except that no indemnification shall be made in respect of any claim, issue or matter as to which such person
  shall have been adjudged to be liable to the corporation unless and only to the extent that the Court of Chancery or the court in which
  such action or suit was brought shall determine upon application that, despite the adjudication of liability but in view of all the circumstances
  of the case, such person is fairly and reasonably entitled to indemnity for such expenses that the Court of Chancery or such other court
  shall deem proper.
  Section
  145 of the DGCL also permits a Delaware corporation to purchase and maintain insurance on behalf of any person who is or was a director,
  officer, employee or agent of the corporation, or is or was serving at the request of the corporation as a director, officer, employee
  or agent of another corporation, partnership, joint venture, trust or other enterprise against any liability asserted against such person
  and incurred by such person in any such capacity, or arising out of such person's status as such, whether or not the corporation
  would have the power to indemnify such person against such liability under Section 145 of the DGCL.
  Article
  Sixth of our Second Amended and Restated Certificate of Incorporation states that to the fullest extent permitted by the DGCL our directors
  shall not be personally liable to us or to our stockholders for monetary damages for breach of fiduciary duty as a director. If the DGCL
  is amended after the date hereof to authorize corporate action further eliminating or limiting the personal liability of directors, then
  the liability of our directors shall be eliminated or limited to the fullest extent permitted by the DGCL, as so amended.
  3
  Article
  Seventh of our Second Amended and Restated Certificate of Incorporation provides that we shall, to the maximum extent and in the manner
  permitted by the DGCL, indemnify each of our directors, officers and all other persons we have the power to indemnify under Section 145
  of the DGCL against expenses (including attorneys' fees), judgments, fines, settlements and other amounts actually and reasonably
  incurred in connection with any proceeding, arising by reason of the fact that such person is or was a director, officer, employee or
  agent of the Company.
  As
  permitted by the DGCL, we have entered into indemnification agreements with each of our directors and executive officers that require
  us to indemnify such persons against various actions including, but not limited to, third-party actions where such director or executive
  officer, by reason of his or her corporate status, is a party or is threatened to be made a party to an action, or by reason of anything
  done or not done by such director in any such capacity. We intend to indemnify directors and executive officers against all costs, judgments,
  penalties, fines, liabilities, amounts paid in settlement by or on behalf such directors or executive officers and for any expenses actually
  and reasonably incurred by such directors or executive officers in connection with such action, if such directors or executive officers
  acted in good faith and in a manner they reasonably believed to be in or not opposed to the best interests of the Company, and with respect
  to any criminal proceeding, had no reasonable cause to believe their conduct was unlawful. We also intend to advance to our directors
  and executive officers expenses (including attorney's fees) incurred by such directors and executive officers in advance of the
  final disposition of any action after the receipt by us of a statement or statements from directors or executive officers requesting
  such payment or payments from time to time, provided that such statement or statements are accompanied by an undertaking, by or on behalf
  of such directors or executive officers, to repay such amount if it shall ultimately be determined that they are not entitled to be indemnified
  against such expenses by us.
  The
  indemnification agreements also set forth certain procedures that will apply in the event of a claim for indemnification or advancement
  of expenses, including, among others, provisions about providing notice to us of any action in connection with which a director or executive
  officer seeks indemnification or advancement of expenses from us and provisions concerning the determination of entitlement to indemnification
  or advancement of expenses.
  Insofar
  as indemnification for liabilities arising under the Securities Act, may be permitted to our directors, officers or persons controlling
  us pursuant to the provisions contained in our Amended and Restated Certificate of Incorporation, Bylaws, the DGCL or otherwise, we have
  been informed that, in the opinion of the SEC, such indemnification is against public policy as expressed in the Securities Act and is
  therefore unenforceable. If a claim for indemnification against such liabilities, other than the payment by us of expenses incurred or
  paid by one of our directors, officers or controlling persons in the successful defense of any action, suit, or proceeding, is asserted
  by such director, officer or controlling person, we will, unless in the opinion of our counsel the matter has been settled by controlling
  precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by us is against public policy as
  expressed in the Securities Act and will be governed by the final adjudication of this issue.
  Item
  7. Exemption from Registration Claimed
  Not
  applicable.
  4
  Item
  8. Exhibits.
  Exhibit
      No.
  Description
      of Exhibits
  Exhibit
  No.
  Description
  Method
  of Filing
  5.1
  Opinion and Consent of Greenberg Traurig, LLP
  Filed
      electronically herewith
  10.1
  TFF Pharmaceuticals, Inc. 2021 Stock Incentive Plan
  Incorporated
      by reference to Appendix A of Registrant's Proxy Statement filed on September 23, 2021
  23.1
  Consent of Marcum LLP
  Filed
      electronically herewith
  23.4
  Consent of Greenberg Traurig, LLP
  Included
      in Exhibit 5.1
  24.1
  Power of Attorney
  Included
      on the signature page to this registration statement
  Item
  9. Undertakings.
  (a)
  The
  undersigned registrant hereby undertakes:
  (1)
  To
  file, during any period in which offers or sales are being made, a post-effective amendment to this registration statement:
  (i)
  To
  include any prospectus required by Section 10(a)(3) of the Securities Act of 1933, as amended (the "Securities Act").
  (ii)
  To
  reflect in the prospectus any facts or events arising after the effective date of the registration statement (or the most recent post-effective
  amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the registration
  statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities
  offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range
  may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) under the Securities Act if, in the aggregate,
  the changes in volume and price represent no more than a 20% change in the maximum aggregate offering price set forth in the "Calculation
  of Registration Fee" table in the effective registration statement.
  (iii)
  To
  include any material information with respect to the plan of distribution not previously disclosed in the registration statement or any
  material change to such information in the registration statement.
  Provided,
  however, that paragraphs (a)(1)(i) and (a)(1)(ii) do not apply if the information required to be included in a post-effective amendment
  by those paragraphs is contained in periodic reports filed with or furnished to the Commission by the registrant pursuant to Section
  13 or section 15(d) of the Exchange Act that are incorporated by reference in the registration statement.
  5
  (2)
  That,
                                              for the purpose of determining any liability under the Securities Act, each such post-effective
                                              amendment shall be deemed to be a new registration statement relating to the securities offered
                                              therein, and the offering of such securities at that time shall be deemed to be the initial
                                              bona fide offering thereof.
  (3)
  To
                                              remove from registration by means of a post-effective amendment any of the securities being
                                              registered which remain unsold at the termination of the offering.
  (b)
  The
                                              undersigned registrant hereby undertakes that, for purposes of determining any liability
                                              under the Securities Act, each filing of the registrant's annual report pursuant to
                                              Section 13(a) or Section 15(d) of the Securities Exchange Act of 1934, as amended (the "Exchange
                                              Act") (and where applicable, each filing of an employee benefit plan's annual
                                              report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in
                                              the registration statement shall be deemed to be a new registration statement relating to
                                              the securities offered therein, and the offering of such securities at that time shall be
                                              deemed to be the initial bona fide offering thereof.
  (c)
  Insofar
                                              as indemnification for liabilities arising under the Securities Act may be permitted to directors,
                                              officers and controlling persons of the registrant pursuant to the foregoing provisions,
                                              or otherwise, the registrant has been advised that in the opinion of the Commission such
                                              indemnification is against public policy as expressed in the Securities Act, and is therefore,
                                              unenforceable. In the event that a claim for indemnification against such liabilities (other
                                              than the payment by the registrant in the successful defense of any action, suit or proceeding)
                                              is asserted by such director, officer or controlling person in connection with the securities
                                              being registered, the registrant will, unless in the opinion of its counsel the matter has
                                              been settled by controlling precedent, submit to a court of appropriate jurisdiction the
                                              question whether such indemnification by it is against public policy as expressed in the
                                              Securities Act and will be governed by the final adjudication of such issue.
  6
  SIGNATURES
  Pursuant
  to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all
  of the requirements of filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned,
  thereunto duly authorized, in the city of Austin, Texas on December 27, 2021.
  TFF PHARMACEUTICALS, INC.
  By:
  /s/ Glenn Mattes
  Glenn Mattes
  Chief Executive Officer
  POWER
  OF ATTORNEY
  Each
  person whose signature appears below hereby constitutes and appoints Glenn Mattes and Kirk Coleman, and each of them, as such person's
  true and lawful attorney-in-fact and agent, each with full powers of substitution and re-substitution, for such person and in such person's
  name, place and stead, in any and all capacities, to sign any or all amendments (including post effective amendments) to this Registration
  Statement, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange
  Commission, granting unto said attorney-in-fact and agent full power and authority to do and perform each and every act and thing requisite
  or necessary to be done in and about the premises, as fully to all intents and purposes as such person might or could do in person, hereby
  ratifying and confirming all that said attorney-in-fact and agent or his or her substitute or substitutes, may lawfully do or cause to
  be done by virtue thereof.
  Pursuant
  to the requirements of the Securities Act of 1933, this Registration Statement has been signed on December 27, 2021 by the following
  persons in the capacities indicated.
  Signature
  Title
  /s/
      Glenn Mattes
  President,
      Chief Executive Officer and Director
  Glenn
      Mattes
  (Principal
      Executive Officer)
  /s/
      Kirk Coleman
  Chief
      Financial Officer (Principal Financial and Accounting Officer)
  Kirk
      Coleman
  /s/
      Aaron Fletcher, Ph.D.
  Chairman
      of the Board
  Aaron
      Fletcher, Ph.D.
  /s/
      Brian Windsor, Ph.D
  Director
  Brian
      Windsor, Ph.D.
  /s/
      Robert S. Mills, Jr.
  Director
  Robert
      S. Mills, Jr.
  /s/
      Stephen C. Rocamboli
  Director
  Stephen
      C. Rocamboli
  /s/
      Harlan Weisman, M.D.
  Director
  Harlan
      Weisman, M.D.
  /s/
      Randy Thurman
  Director
  Randy
      Thurman
  /s/
      Malcolm Fairbairn
  Director
  Malcolm
      Fairbairn
  7
  INDEX
  TO EXHIBITS
  No.
  Item
  Method of Filing
  5.1
  Opinion and Consent of Greenberg Traurig, LLP
  Filed
      electronically herewith
  23.1
  Consent of Marcum LLP
  Filed
      electronically herewith
  23.4
  Consent of Greenberg Traurig, LLP
  Included
      in Exhibit 5.1
  24.1
  Power of Attorney
  Included
      on the signature page to this registration statement
  10.1
  TFF Pharmaceuticals, Inc. 2021 Stock Incentive Plan
  Incorporated
      by reference to Appendix A of Registrant's Proxy Statement filed on September 23, 2021
  8