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    <td colspan="2" align="center"><b><font size=2 face="serif">As filed with the Securities and Exchange Commission on September 14, 2004 </font></b></td>
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    <td width="76%">&nbsp;</td>
    <td width="24%"><b><font size=2 face="serif">Registration No. 333-_
    ______</font></b> </td>
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  <TD colspan="3" align="center"><p><font size=5 face="serif">UNITED STATES<br>
    SECURITIES AND EXCHANGE COMMISSION</font><br>
<font face="serif">Washington, D.C. 20549 </font> </p></TD>
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<TR>
  <TD align="center">&nbsp;</TD>
  <TD align="center"><font size=5 face="serif">FORM S-8</font><font size=5 face="serif"> </font><br>
<font size=2 face="serif">REGISTRATION STATEMENT </font> <br>
<font size=2 face="serif">UNDER </font> <br>
<font size=2 face="serif">THE SECURITIES ACT OF 1933</font></TD>
  <TD align="center">&nbsp;</TD>
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<TR>
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   <TD width="30%" align="center">&nbsp;</TD>
   <TD align="center" width="40%"><FONT size=5 face="serif">GENTA INCORPORATED</FONT></TD>
   <TD align="center" width="30%">&nbsp;</TD>
</TR>
<TR>
   <TD width="30%" align="center">&nbsp;</TD>
   <TD width="40%" align="center"><FONT size=1 face="serif">(Exact Name of Registrant as Specified in Its Charter)</FONT></TD>
   <TD width="30%" align="center">&nbsp;</TD>
</TR>
<TR>
  <TD align="center">&nbsp;</TD>
  <TD align="center">&nbsp;</TD>
  <TD align="center">&nbsp;</TD>
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   <TD width="30%" align="center"><B><FONT size=2 face="serif">Delaware</FONT></B></TD>
   <TD align="center" width="40%"><B><FONT size=2 face="serif">2836</FONT></B></TD>
   <TD width="30%" align="center"><B><FONT size=2 face="serif">33-0326866</FONT></B></TD>
</TR>
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   <TD width="30%" align="center"><FONT size=1 face="serif">(State or Other Jurisdiction of Incorporation or Organization)</FONT></TD>
   <TD align="center" width="40%"><FONT size=1 face="serif">(Primary Standard Industrial Classification Code Number)</FONT></TD>
   <TD align="center" width="30%"><FONT size=1 face="serif">(I.R.S. Employer Identification Number)</FONT></TD>
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   <TD width="30%" align="center">&nbsp;</TD>
   <TD align="center" width="40%">&nbsp;</TD>
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   <TD width="30%" align="center">&nbsp;</TD>
   <TD align="center" width="40%"><B><FONT size=2 face="serif">Two Connell Drive</FONT></B></TD>
   <TD width="30%" align="center">&nbsp;</TD>
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   <TD width="30%" align="center">&nbsp;</TD>
   <TD align="center" width="40%"><B><FONT size=2 face="serif">Berkeley Heights, NJ 07922</FONT></B></TD>
   <TD width="30%" align="center">&nbsp;</TD>
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   <TD width="30%" align="center">&nbsp;</TD>
   <TD align="center" width="40%"><B><FONT size=2 face="serif">(908) 286-9800</FONT></B></TD>
   <TD width="30%" align="center">&nbsp;</TD>
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<TR>
  <TD colspan="3" align="center"><font size=1 face="serif">(Address, Including Zip Code, and Telephone Number, Including Area Code, of Registrant&#146;s Principal Executive Offices)</font></TD>
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  <TD align="center">&nbsp;</TD>
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  <TD align="center">&nbsp;</TD>
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  <TD colspan="3" align="center"><b><font size=2 face="serif">GENTA INCORPORATED 1998 STOCK INCENTIVE PLAN</font></b> <br>
    <font size=1 face="serif">(Full title of the plan) </font> </TD>
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<P align="center">
<B><FONT size=2 face="serif"> 	William P. Keane 	 <br>
Vice President, Chief Financial Officer <br>
and Corporate Secretary <br>
Genta Incorporated <br>
Two Connell Drive <br>
Berkeley Heights, NJ 07922 <br>
(908) 286-9800 </FONT></B>
<br>

<FONT size=1 face="serif">(Name, Address, Including Zip Code, and Telephone Number, Including Area Code, of Agent For Service)</FONT>
</P>
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  <TD align="center">&nbsp;</TD>
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<P align="center">
<B><I><FONT size=2 face="serif">Copy to: </FONT></I></B>
<br>

<B><FONT size=2 face="serif">Richard A. Drucker <br>
Davis Polk &amp; Wardwell <br>
450 Lexington Avenue <br>
New York, New York 10017 <br>
(212) 450-4000 </FONT></B>
</P>
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<P align="center">
<B><FONT size=2 face="serif">CALCULATION OF REGISTRATION FEE</FONT></B>
</P>


<table width="95%"  border="2" cellspacing="0" cellpadding="5">
  <tr align="center" valign="bottom">
    <td width="40%"><b><font size=1 face="serif">Title Of Each Class<br>
    Of Securities To Be Registered</font></b></td>
    <td width="20%"><b><font size=1 face="serif">Amount To Be<br>
    Registered (1)</font></b></td>
    <td width="20%"><b><font size=1 face="serif">Proposed<br>
    Maximum<br>
    Offering Price<br>
    Per Unit (2)</font></b></td>
    <td width="20%"><b><font size=1 face="serif">Proposed<br>
    Maximum<br>
    Aggregate <br>
    Offering Price (2) </font></b> <b><font size=1 face="serif"><br>
    </font></b></td>
    <td width="20%"><b><font size=1 face="serif">Amount Of<br>
    Registration Fee </font></b></td>
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    <td><font size=2 face="serif">Common Stock, par value $.001 per share</font> </td>
    <td align="center"><font size=2 face="serif">2,900,000 </font> </td>
    <td align="center"><font size="2">$2.575</font></td>
    <td align="center"><font size="2">$7,467,500</font></td>
    <td align="center"><font size="2">$946.13</font></td>
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  <tr>
    <td width="3%" align="left" valign="top"><font size=2 face="serif">(1) </font> </td>
    <td width="3%" align="left" valign="top">&nbsp;</td>
    <td width="94%" valign="top"><font size=2 face="serif">Pursuant to Rule 416 under the Securities Act of 1933,
	this Registration Statement also covers such additional shares as may
	hereinafter be offered or issued to prevent dilution resulting from stock splits, stock dividends,
	stock recapitalizations or certain other capital adjustments. </font> </td>
  </tr>
  <tr>
    <td align="left" valign="top">&nbsp;</td>
    <td align="left" valign="top">&nbsp;</td>
    <td valign="top">&nbsp;</td>
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  <tr>
    <td width="3%" align="left" valign="top"><font size=2 face="serif">(2)</font></td>
    <td width="3%" align="left" valign="top">&nbsp;</td>
    <td width="94%" valign="top"><font size=2 face="serif">Estimated solely for
        the purpose of computing  the amount of the registration fee pursuant
        to Rule 457(c) under the Securities Act of 1933 based on  the average
        of the high and low prices of the Common Stock on the Nasdaq National
        Market on  September 10, 2004. </font></td>
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</table>


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<P align="center">
<B><FONT size=2 face="serif">PART II </FONT></B>
</P>
<P align="center">
<B><FONT size=2 face="serif">INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</FONT></B><FONT size=2 face="serif"> </FONT>
</P>
<P>
<B><FONT size=2 face="serif">Item 3. Incorporation of Documents by Reference. </FONT></B>
</P>
<P>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<FONT size=2 face="serif">The following documents
filed by Genta  Incorporated (&#147;Genta&#148;) with the Securities and Exchange
Commission  pursuant to the Securities Exchange Act of 1934, as amended (the
&#147;Exchange Act&#148;), are incorporated in this Registration Statement by
reference: </FONT>
</P>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">1. Our Annual Report on Form 10-K for the fiscal year ended December 31, 2003. </FONT>
</P>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">2. Our Quarterly Reports on Form 10-Q for the quarterly periods ended March 31 and June 30, 2004. </FONT>
</P>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">3. Our Current Reports on Form 8-K filed on April 30, May 3, May 13, May 14, June 1, June 7, June 21 and </FONT><FONT size=2 face="serif">July 29, 2004. </FONT>
</P>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">4. The description of our shares of common stock contained
in the Registration Statement on Form S-3 that was filed on April 2, 2004 and
any subsequent amendments thereto, or in a Registration  Statement on Form 8-A,
updating such description. </FONT>
</P>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">5. All other documents filed by us pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act subsequent to the date of this Registration Statement and prior to the filing of a
post-effective amendment which indicates that all securities offered herein have been sold or which deregisters all securities then remaining unsold. </FONT>
</P>
<P>
<B><FONT size=2 face="serif">Item 4. Description of Securities. </FONT></B>
</P>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">Not applicable. </FONT>
</P>
<P>
<B><FONT size=2 face="serif">Item 5. Interests of Named Experts and Counsel. </FONT></B>
</P>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">Not applicable. </FONT>
</P>
<P>
<B><FONT size=2 face="serif">Item 6. Indemnification of Officers and Directors.</FONT></B><FONT size=2 face="serif"> </FONT>
</P>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">Section 102(b)(7) of the Delaware General Corporation Law (the &#147;DGCL&#148;) permits a corporation to provide in its certificate of incorporation that a director of the corporation shall
not be personally liable to the corporation or its stockholders for monetary damages for breach of fiduciary duty as a director, except for liability (i) for any breach of the director&#146;s duty of loyalty to the corporation or its stockholders,
(ii) for acts or omissions not in good faith or which involve intentional misconduct or a knowing violation of law, (iii) for unlawful payments of dividends or unlawful stock repurchases, redemptions or other distributions, or (iv) for any
transaction from which the director derived an improper personal benefit. </FONT>
</P>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">Section 145 of the DGCL provides that a corporation may indemnify any person, including a director or officer, who is, or is threatened to be made, a party to any threatened, pending or
completed legal action, suit or proceeding, whether civil, criminal, administrative or investigative (other than an action by or in the right of such corporation), by reason of fact that such person is or was a director, officer, employee or agent
of such corporation, or is or was serving at the request of such corporation as a director, officer, employee or agent of another corporation or other enterprise against expenses (including attorney&#146;s fees), judgments, fines and amounts paid in
settlement actually and reasonably incurred by such person in connection with such action, suit or proceeding, provided such person acted good faith and in a manner he or she reasonably believed to be in or not opposed to the corporation&#146;s best
interests and, with respect to any criminal actions or proceedings, had no reasonable cause to believe that his or her conduct was unlawful. A Delaware corporation may provide similar indemnification in an action or suit by or in the right of the
corporation, except that no indemnification is permitted if the director or officer is adjudged to be liable to the corporation unless and to the extent the Court of Chancery or the court in which such action was brought determines that such person
is reasonably entitled to indemnify. Where a director or officer is successful on the merits or </FONT>
</P>

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<P>
<FONT size=2 face="serif">otherwise in the defense of any action referred to above, the corporation must indemnify him or her against the expenses which such director or officer actually and reasonably incurred. </FONT>
</P>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">Article VIII of Genta&#146;s restated certificate of incorporation, as amended, provides indemnification of directors and officers of Genta to the fullest extent permitted by the DGCL. </FONT>
</P>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">Genta maintains liability insurance for each director and officer for certain losses arising from claims or charges made against them while acting in their capacities as directors or officers
of Genta. </FONT>
</P>
<P>
<B><FONT size=2 face="serif">Item 7. Exemption From Registration Claimed. </FONT></B>
</P>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">Not applicable. </FONT>
</P>
<P>
<B><FONT size=2 face="serif">Item 8. Exhibits. </FONT></B>
</P>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">The following Exhibits are filed as part of this Registration Statement: </FONT>
</P>
<TABLE width="100%" border=0 cellspacing=0 cellpadding=0>
<TR>
   <TD width="3%">&nbsp;</TD>
   <TD align="center" width="4%"><B><FONT size=1 face="serif">Exhibit<br>
    Number</FONT></B></TD>
   <TD align="center" width="3%">&nbsp;</TD>
   <TD align="center" width="11%"><B><FONT size=1 face="serif">Description</FONT></B></TD>
   <TD align="center" width="79%">&nbsp;</TD>
</TR>
<TR>
   <TD width="3%">&nbsp;</TD>
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   <TD width="3%">&nbsp;</TD>
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   <TD>&nbsp;</TD>
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<TR>
   <TD width="3%">&nbsp;</TD>
   <TD width="4%"><font size=2 face="serif">5</font></TD>
   <TD width="3%">&nbsp;</TD>
   <TD colspan="2"><FONT size=2 face="serif">Opinion of Davis Polk &amp; Wardwell</FONT></TD>
</TR>
<TR>
   <TD width="3%">&nbsp;</TD>
   <TD width="4%"><font size=2 face="serif">23.1</font></TD>
   <TD width="3%">&nbsp;</TD>
   <TD colspan="2"><FONT size=2 face="serif">Consent of Deloitte &amp; Touche LLP</FONT></TD>
</TR>
<TR>
   <TD width="3%">&nbsp;</TD>
   <TD width="4%"><font size=2 face="serif">23.2</font></TD>
   <TD width="3%">&nbsp;</TD>
   <TD colspan="2"><FONT size=2 face="serif">Consent of Davis Polk &amp; Wardwell (included in Exhibit 5)</FONT></TD>
</TR>
<TR>
   <TD width="3%">&nbsp;</TD>
   <TD width="4%"><font size=2 face="serif">24</font></TD>
   <TD width="3%">&nbsp;</TD>
   <TD colspan="2"><FONT size=2 face="serif">Power of Attorney (included on signature page)</FONT></TD>
</TR>
</TABLE>
<P>
<B><FONT size=2 face="serif">Item 9. Undertakings. </FONT></B>
</P>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">The undersigned registrant hereby undertakes: </FONT>
</P>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">(a) (1) To file, during any period in which offers or sales are being made of securities registered hereby, a post-effective amendment to this registration statement to include any material
information with respect to the plan of distribution not previously disclosed in the registration statement or any material change to such information in the registration statement; </FONT>
</P>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">(2) That, for the purpose of determining any liability under the Securities Act of 1933, each such post-effective amendment shall be deemed to be a new registration statement relating to the
securities offered therein, and the offering of such securities at that time shall be deemed to be the initial </FONT><I><FONT size=2 face="serif">bona fide</FONT></I><FONT size=2 face="serif"> offering thereof. </FONT>
</P>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">(3) To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering. </FONT>
</P>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">(b) That, for the purpose of determining any liability under the Securities Act of 1933, each filing of the registrant&#146;s annual report pursuant to Section 13(a) or 15(d) of the Securities
Exchange Act of 1934 that is incorporated by reference in the registration statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to
be initial </FONT><I><FONT size=2 face="serif">bona fide</FONT></I><FONT size=2 face="serif"> offering thereof. </FONT>
</P>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">(c) Insofar as indemnification for liabilities arising under the Securities Act of 1933 may be permitted to directors, officers and controlling persons of the registrant pursuant to the
provisions referenced in Item 6 of this Registration Statement, or otherwise, the registrant has been advised that in the opinion of the Securities and Exchange Commission such indemnification is against public policy as expressed in the Act and is,
therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the registrant of expenses incurred or paid by a director, officer or controlling person of the registrant in the successful
defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered hereunder, the registrant will, unless in the opinion of its counsel the matter has been
settled by controlling precedent, submit to a court of appropriate jurisdiction the question of whether such </FONT>
</P>

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<FONT size=2 face="serif">indemnification by it is against public policy as expressed in the Act and will be governed by the final adjudication of such issue. </FONT>
<P>&nbsp;
</P>

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<P>
<B><FONT size=2 face="serif">SIGNATURES </FONT></B>
</P>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">Pursuant to the requirements of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and
has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Berkeley Heights, State of New Jersey, on the 14</FONT><SUP><FONT size=2 face="serif">th</FONT></SUP><FONT size=2
face="serif"> day of September, 2004. </FONT>
</P>
<div align=right>
<TABLE width="55%" border=0 cellspacing=0 cellpadding=0>
<TR>
   <TD colspan="3"><FONT size=2 face="serif">GENTA INCORPORATED</FONT></TD>
   </TR>
<TR>
   <TD colspan="3"><FONT size=2 face="serif">(Registrant)</FONT></TD>
   </TR>
<TR>
   <TD width="4%">&nbsp;</TD>
   <TD width="7%">&nbsp;</TD>
   <TD width="89%">&nbsp;</TD>
</TR>
<TR>
   <TD width="4%">&nbsp;</TD>
   <TD width="7%">&nbsp;</TD>
   <TD width="89%">&nbsp;</TD>
</TR>
<TR>
   <TD width="4%"><FONT size=2 face="serif">By:</FONT></TD>
   <TD colspan="2"><font size="2">/s/ William P. Keane</font> </TD>
   </TR>
<TR>
  <TD width="4%">&nbsp;</TD>
  <TD colspan="2"><hr align="left" width="50%" size=1 noshade>    </TD>
  </TR>
<TR>
   <TD width="4%">&nbsp;&nbsp;&nbsp;</TD>
   <TD width="7%"><font size=2 face="serif">Name:</font></TD>
   <TD width="89%"><font size="2">&nbsp;William P. Keane</font> </TD>
</TR>
<TR valign="top">
   <TD width="4%">&nbsp;&nbsp;</TD>
   <TD width="7%"><font size=2 face="serif">Title:</font></TD>
   <TD width="89%"><font size="2">&nbsp;Vice President, Chief Financial Officer<br>
     &nbsp;and Corporate Secretary </font></TD>
</TR>
</TABLE>
</div>
<br>
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<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Raymond P. Warrell, Jr., M.D., William P. Keane and Stefan Grant, and each of them, his
or her true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution, for him or her and in his or her name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective
amendments) to this registration statement and any and all amendments to this Registration Statement, and to file the same, with all exhibits thereto, and all other documents in connection therewith, with the Securities and Exchange Commission,
granting unto each said attorney-in-fact and agents full power and authority to do and perform each and every act in person, hereby ratifying and confirming all that said attorneys-in-fact and agents or either of them or their or his or her
substitute or substitutes may lawfully do or cause to be done by virtue hereof. </FONT>
<P>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<FONT size=2 face="serif">Pursuant to the requirements of the Securities Act of 1933, as amended, this Registration Statement has been signed by the following persons in the capacities and on the dates indicated.</FONT>
</P>
<TABLE width="100%" border=0 cellspacing=0 cellpadding=0>
<TR>
   <TD width="35%" align="center"><B><FONT size=2 face="serif">Signature</FONT></B></TD>
   <TD align="center" width="2%">&nbsp;</TD>
   <TD align="center" width="35%"><B><FONT size=2 face="serif">Title</FONT></B></TD>
   <TD align="center" width="2%">&nbsp;</TD>
   <TD align="center" width="26%"><B><FONT size=2 face="serif">Date</FONT></B></TD>
</TR>
<TR>
   <TD width="35%" align="center">&nbsp;</TD>
   <TD width="2%" align="center">&nbsp;</TD>
   <TD width="35%" align="center">&nbsp;</TD>
   <TD width="2%" align="center">&nbsp;</TD>
   <TD width="26%" align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><FONT size=2 face="serif">/s/ Raymond P. Warrell,
    Jr., M.D.</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center"><FONT size=2 face="serif">Chairman of the Board of Directors and</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><hr noshade size=1>    </TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center"><FONT size=2 face="serif">Chief Executive Officer (Principal</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><FONT size=2 face="serif">Raymond P. Warrell, Jr., M.D.</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center"><FONT size=2 face="serif">Executive Officer)</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center"><FONT size=2 face="serif">September 14, 2004</FONT></TD>
</TR>
<TR>
  <TD align="center">&nbsp;</TD>
  <TD>&nbsp;</TD>
  <TD align="center">&nbsp;</TD>
  <TD>&nbsp;</TD>
  <TD align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><FONT size=2 face="serif">/s/ William P. Keane</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center"><FONT size=2 face="serif">Vice President, Chief Financial Officer</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><hr noshade size=1>    </TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center"><FONT size=2 face="serif">and Corporate Secretary (Principal</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><FONT size=2 face="serif">William P. Keane</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center"><FONT size=2 face="serif">Accounting Officer)</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center"><FONT size=2 face="serif">September 14, 2004</FONT></TD>
</TR>
<TR>
  <TD align="center">&nbsp;</TD>
  <TD>&nbsp;</TD>
  <TD align="center">&nbsp;</TD>
  <TD>&nbsp;</TD>
  <TD align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><FONT size=2 face="serif">/s/ Jerome E. Groopman,
    M.D.</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center">&nbsp;</TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><hr noshade size=1>    </TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center">&nbsp;</TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><FONT size=2 face="serif">Jerome E. Groopman, M.D.</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center"><FONT size=2 face="serif">Director</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center"><FONT size=2 face="serif">September 14, 2004</FONT></TD>
</TR>
<TR>
  <TD align="center">&nbsp;</TD>
  <TD>&nbsp;</TD>
  <TD align="center">&nbsp;</TD>
  <TD>&nbsp;</TD>
  <TD align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><FONT size=2 face="serif">/s/ Betsy McCaughey,
    Ph.D.</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center">&nbsp;</TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><hr noshade size=1>    </TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center">&nbsp;</TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center">&nbsp;<FONT size=2 face="serif">Betsy McCaughey, Ph.D.</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center"><FONT size=2 face="serif">Director</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center"><FONT size=2 face="serif">September 14, 2004</FONT></TD>
</TR>
<TR>
  <TD align="center">&nbsp;</TD>
  <TD>&nbsp;</TD>
  <TD align="center">&nbsp;</TD>
  <TD>&nbsp;</TD>
  <TD align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><FONT size=2 face="serif">/s/ Peter T. Tattle</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center">&nbsp;</TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><hr noshade size=1>    </TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center">&nbsp;</TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><FONT size=2 face="serif">Peter T. Tattle</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center"><FONT size=2 face="serif">Director</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center"><FONT size=2 face="serif">September 14, 2004</FONT></TD>
</TR>
<TR>
  <TD align="center">&nbsp;</TD>
  <TD>&nbsp;</TD>
  <TD align="center">&nbsp;</TD>
  <TD>&nbsp;</TD>
  <TD align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><FONT size=2 face="serif">/s/ Daniel D. Von
       Hoff, M.D.</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center">&nbsp;</TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><hr noshade size=1>    </TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center">&nbsp;</TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><FONT size=2 face="serif">Daniel D. Von Hoff, M.D.</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center"><FONT size=2 face="serif">Director</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center"><FONT size=2 face="serif">September 14, 2004</FONT></TD>
</TR>
<TR>
  <TD align="center">&nbsp;</TD>
  <TD>&nbsp;</TD>
  <TD align="center">&nbsp;</TD>
  <TD>&nbsp;</TD>
  <TD align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><FONT size=2 face="serif">/s/ Harlan J. Wakoff</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center">&nbsp;</TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><hr noshade size=1>    </TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center">&nbsp;</TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><FONT size=2 face="serif">Harlan J. Wakoff</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center"><FONT size=2 face="serif">Director</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center"><FONT size=2 face="serif">September 14, 2004</FONT></TD>
</TR>
<TR>
  <TD align="center">&nbsp;</TD>
  <TD>&nbsp;</TD>
  <TD align="center">&nbsp;</TD>
  <TD>&nbsp;</TD>
  <TD align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><FONT size=2 face="serif">/s/ Douglas G. Watson</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center">&nbsp;</TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><hr noshade size=1>    </TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center">&nbsp;</TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><FONT size=2 face="serif">Douglas G. Watson</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center"><FONT size=2 face="serif">Director</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center"><FONT size=2 face="serif">September 14, 2004</FONT></TD>
</TR>
<TR>
  <TD align="center">&nbsp;</TD>
  <TD>&nbsp;</TD>
  <TD align="center">&nbsp;</TD>
  <TD>&nbsp;</TD>
  <TD align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><FONT size=2 face="serif">/s/ Michael S. Weiss</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center">&nbsp;</TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><hr noshade size=1>    </TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center">&nbsp;</TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="35%" align="center"><FONT size=2 face="serif">Michael S. Weiss</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="35%" align="center"><FONT size=2 face="serif">Director</FONT></TD>
   <TD width="2%">&nbsp;</TD>
   <TD width="26%" align="center"><FONT size=2 face="serif">September 14, 2004</FONT></TD>
</TR>
</TABLE>

<br>
<br>
<hr size=3 color=GRAY noshade>
<!-- *************************************************************************** -->
<!-- MARKER PAGE="sheet: 1; page: 1" -->
<br>
<br>
<br>


<TABLE width="95%" border=0 cellspacing=0 cellpadding=0>
<TR>
  <TD>&nbsp;</TD>
  <TD align="center">&nbsp;</TD>
  <TD align="center">&nbsp;</TD>
  <TD align="center"><b><font size=2 face="serif">EXHIBIT INDEX</font></b></TD>
  <TD align="center">&nbsp;</TD>
</TR>
<TR>
   <TD width="3%">&nbsp;</TD>
   <TD align="center" width="4%"><B><FONT size=1 face="serif"></FONT></B></TD>
   <TD align="center" width="3%">&nbsp;</TD>
   <TD align="center">&nbsp;</TD>
   <TD align="center">&nbsp;</TD>
</TR>
<TR valign="bottom">
   <TD width="3%">&nbsp;</TD>
   <TD width="4%" align="center"><B><FONT size=1 face="serif">Exhibit<br>
Number</FONT></B></TD>
   <TD width="3%" align="center">&nbsp;</TD>
   <TD width="67%" align="center"><B><FONT size=1 face="serif">Description</FONT></B></TD>
   <TD width="23%" align="center"><b><font size=1 face="serif">Sequentially<br>
    Numbered Page</font></b></TD>
</TR>
<TR>
   <TD width="3%">&nbsp;</TD>
   <TD width="4%">&nbsp;</TD>
   <TD width="3%">&nbsp;</TD>
   <TD>&nbsp;    </TD>
   <TD>&nbsp;</TD>
</TR>
<TR>
   <TD width="3%">&nbsp;</TD>
   <TD width="4%"><font size=2 face="serif">5</font></TD>
   <TD width="3%">&nbsp;</TD>
   <TD><FONT size=2 face="serif">Opinion of Davis Polk &amp; Wardwell</FONT></TD>
   <TD>&nbsp;</TD>
</TR>
<TR>
   <TD width="3%">&nbsp;</TD>
   <TD width="4%"><font size=2 face="serif">23.1</font></TD>
   <TD width="3%">&nbsp;</TD>
   <TD><FONT size=2 face="serif">Consent of Deloitte &amp; Touche LLP</FONT></TD>
   <TD>&nbsp;</TD>
</TR>
<TR>
   <TD width="3%">&nbsp;</TD>
   <TD width="4%"><font size=2 face="serif">23.2</font></TD>
   <TD width="3%">&nbsp;</TD>
   <TD><FONT size=2 face="serif">Consent of Davis Polk &amp; Wardwell (included in Exhibit 5)</FONT></TD>
   <TD>&nbsp;</TD>
</TR>
<TR>
   <TD width="3%">&nbsp;</TD>
   <TD width="4%"><font size=2 face="serif">24</font></TD>
   <TD width="3%">&nbsp;</TD>
   <TD><FONT size=2 face="serif">Power of Attorney (included on signature page)</FONT></TD>
   <TD>&nbsp;</TD>
</TR>
</TABLE>
<br>
<br>
<HR noshade align="center" width="100%" size=3>
</BODY>
</HTML>
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{"company-data": {"conformed-name": "GENTA INC DE/", "cik": "0000880643", "assigned-sic": "2836", "irs-number": "330326866", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-118987", "film-number": "041030535"}, "business-address": {"street1": "TWO CONNELL DRIVE", "street2": "..", "city": "BERKELEY HEIGHTS", "state": "NJ", "zip": "07922", "phone": "(908) 286-9800"}, "mail-address": {"street1": "TWO CONNELL DRIVE", "street2": "..", "city": "BERKELEY HEIGHTS", "state": "NJ", "zip": "07922"}}
sep1004_s8
As filed with the Securities and Exchange Commission on September 14, 2004
Registration No. 333-_
    ______
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-8
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
GENTA INCORPORATED
(Exact Name of Registrant as Specified in Its Charter)
Delaware
2836
33-0326866
(State or Other Jurisdiction of Incorporation or Organization)
(Primary Standard Industrial Classification Code Number)
(I.R.S. Employer Identification Number)
Two Connell Drive
Berkeley Heights, NJ 07922
(908) 286-9800
(Address, Including Zip Code, and Telephone Number, Including Area Code, of Registrant's Principal Executive Offices)
GENTA INCORPORATED 1998 STOCK INCENTIVE PLAN
(Full title of the plan)
William P. Keane
Vice President, Chief Financial Officer
and Corporate Secretary
Genta Incorporated
Two Connell Drive
Berkeley Heights, NJ 07922
(908) 286-9800
(Name, Address, Including Zip Code, and Telephone Number, Including Area Code, of Agent For Service)
Copy to:
Richard A. Drucker
Davis Polk & Wardwell
450 Lexington Avenue
New York, New York 10017
(212) 450-4000
CALCULATION OF REGISTRATION FEE
Title Of Each Class
Of Securities To Be Registered
Amount To Be
Registered (1)
Proposed
Maximum
Offering Price
Per Unit (2)
Proposed
Maximum
Aggregate
Offering Price (2)
Amount Of
Registration Fee
Common Stock, par value $.001 per share
2,900,000
$2.575
$7,467,500
$946.13
(1)
Pursuant to Rule 416 under the Securities Act of 1933,
	this Registration Statement also covers such additional shares as may
	hereinafter be offered or issued to prevent dilution resulting from stock splits, stock dividends,
	stock recapitalizations or certain other capital adjustments.
(2)
Estimated solely for
        the purpose of computing  the amount of the registration fee pursuant
        to Rule 457(c) under the Securities Act of 1933 based on  the average
        of the high and low prices of the Common Stock on the Nasdaq National
        Market on  September 10, 2004.
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 3. Incorporation of Documents by Reference.
The following documents
filed by Genta  Incorporated ("Genta") with the Securities and Exchange
Commission  pursuant to the Securities Exchange Act of 1934, as amended (the
"Exchange Act"), are incorporated in this Registration Statement by
reference:
1. Our Annual Report on Form 10-K for the fiscal year ended December 31, 2003.
2. Our Quarterly Reports on Form 10-Q for the quarterly periods ended March 31 and June 30, 2004.
3. Our Current Reports on Form 8-K filed on April 30, May 3, May 13, May 14, June 1, June 7, June 21 and
July 29, 2004.
4. The description of our shares of common stock contained
in the Registration Statement on Form S-3 that was filed on April 2, 2004 and
any subsequent amendments thereto, or in a Registration  Statement on Form 8-A,
updating such description.
5. All other documents filed by us pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act subsequent to the date of this Registration Statement and prior to the filing of a
post-effective amendment which indicates that all securities offered herein have been sold or which deregisters all securities then remaining unsold.
Item 4. Description of Securities.
Not applicable.
Item 5. Interests of Named Experts and Counsel.
Not applicable.
Item 6. Indemnification of Officers and Directors.
Section 102(b)(7) of the Delaware General Corporation Law (the "DGCL") permits a corporation to provide in its certificate of incorporation that a director of the corporation shall
not be personally liable to the corporation or its stockholders for monetary damages for breach of fiduciary duty as a director, except for liability (i) for any breach of the director's duty of loyalty to the corporation or its stockholders,
(ii) for acts or omissions not in good faith or which involve intentional misconduct or a knowing violation of law, (iii) for unlawful payments of dividends or unlawful stock repurchases, redemptions or other distributions, or (iv) for any
transaction from which the director derived an improper personal benefit.
Section 145 of the DGCL provides that a corporation may indemnify any person, including a director or officer, who is, or is threatened to be made, a party to any threatened, pending or
completed legal action, suit or proceeding, whether civil, criminal, administrative or investigative (other than an action by or in the right of such corporation), by reason of fact that such person is or was a director, officer, employee or agent
of such corporation, or is or was serving at the request of such corporation as a director, officer, employee or agent of another corporation or other enterprise against expenses (including attorney's fees), judgments, fines and amounts paid in
settlement actually and reasonably incurred by such person in connection with such action, suit or proceeding, provided such person acted good faith and in a manner he or she reasonably believed to be in or not opposed to the corporation's best
interests and, with respect to any criminal actions or proceedings, had no reasonable cause to believe that his or her conduct was unlawful. A Delaware corporation may provide similar indemnification in an action or suit by or in the right of the
corporation, except that no indemnification is permitted if the director or officer is adjudged to be liable to the corporation unless and to the extent the Court of Chancery or the court in which such action was brought determines that such person
is reasonably entitled to indemnify. Where a director or officer is successful on the merits or
otherwise in the defense of any action referred to above, the corporation must indemnify him or her against the expenses which such director or officer actually and reasonably incurred.
Article VIII of Genta's restated certificate of incorporation, as amended, provides indemnification of directors and officers of Genta to the fullest extent permitted by the DGCL.
Genta maintains liability insurance for each director and officer for certain losses arising from claims or charges made against them while acting in their capacities as directors or officers
of Genta.
Item 7. Exemption From Registration Claimed.
Not applicable.
Item 8. Exhibits.
The following Exhibits are filed as part of this Registration Statement:
Exhibit
Number
Description
5
Opinion of Davis Polk & Wardwell
23.1
Consent of Deloitte & Touche LLP
23.2
Consent of Davis Polk & Wardwell (included in Exhibit 5)
24
Power of Attorney (included on signature page)
Item 9. Undertakings.
The undersigned registrant hereby undertakes:
(a) (1) To file, during any period in which offers or sales are being made of securities registered hereby, a post-effective amendment to this registration statement to include any material
information with respect to the plan of distribution not previously disclosed in the registration statement or any material change to such information in the registration statement;
(2) That, for the purpose of determining any liability under the Securities Act of 1933, each such post-effective amendment shall be deemed to be a new registration statement relating to the
securities offered therein, and the offering of such securities at that time shall be deemed to be the initial
bona fide
offering thereof.
(3) To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.
(b) That, for the purpose of determining any liability under the Securities Act of 1933, each filing of the registrant's annual report pursuant to Section 13(a) or 15(d) of the Securities
Exchange Act of 1934 that is incorporated by reference in the registration statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to
be initial
bona fide
offering thereof.
(c) Insofar as indemnification for liabilities arising under the Securities Act of 1933 may be permitted to directors, officers and controlling persons of the registrant pursuant to the
provisions referenced in Item 6 of this Registration Statement, or otherwise, the registrant has been advised that in the opinion of the Securities and Exchange Commission such indemnification is against public policy as expressed in the Act and is,
therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the registrant of expenses incurred or paid by a director, officer or controlling person of the registrant in the successful
defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered hereunder, the registrant will, unless in the opinion of its counsel the matter has been
settled by controlling precedent, submit to a court of appropriate jurisdiction the question of whether such
indemnification by it is against public policy as expressed in the Act and will be governed by the final adjudication of such issue.
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and
has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Berkeley Heights, State of New Jersey, on the 14
th
day of September, 2004.
GENTA INCORPORATED
(Registrant)
By:
/s/ William P. Keane
Name:
William P. Keane
Title:
Vice President, Chief Financial Officer
and Corporate Secretary
KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Raymond P. Warrell, Jr., M.D., William P. Keane and Stefan Grant, and each of them, his
or her true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution, for him or her and in his or her name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective
amendments) to this registration statement and any and all amendments to this Registration Statement, and to file the same, with all exhibits thereto, and all other documents in connection therewith, with the Securities and Exchange Commission,
granting unto each said attorney-in-fact and agents full power and authority to do and perform each and every act in person, hereby ratifying and confirming all that said attorneys-in-fact and agents or either of them or their or his or her
substitute or substitutes may lawfully do or cause to be done by virtue hereof.
Pursuant to the requirements of the Securities Act of 1933, as amended, this Registration Statement has been signed by the following persons in the capacities and on the dates indicated.
Signature
Title
Date
/s/ Raymond P. Warrell,
    Jr., M.D.
Chairman of the Board of Directors and
Chief Executive Officer (Principal
Raymond P. Warrell, Jr., M.D.
Executive Officer)
September 14, 2004
/s/ William P. Keane
Vice President, Chief Financial Officer
and Corporate Secretary (Principal
William P. Keane
Accounting Officer)
September 14, 2004
/s/ Jerome E. Groopman,
    M.D.
Jerome E. Groopman, M.D.
Director
September 14, 2004
/s/ Betsy McCaughey,
    Ph.D.
Betsy McCaughey, Ph.D.
Director
September 14, 2004
/s/ Peter T. Tattle
Peter T. Tattle
Director
September 14, 2004
/s/ Daniel D. Von
       Hoff, M.D.
Daniel D. Von Hoff, M.D.
Director
September 14, 2004
/s/ Harlan J. Wakoff
Harlan J. Wakoff
Director
September 14, 2004
/s/ Douglas G. Watson
Douglas G. Watson
Director
September 14, 2004
/s/ Michael S. Weiss
Michael S. Weiss
Director
September 14, 2004
EXHIBIT INDEX
Exhibit
Number
Description
Sequentially
Numbered Page
5
Opinion of Davis Polk & Wardwell
23.1
Consent of Deloitte & Touche LLP
23.2
Consent of Davis Polk & Wardwell (included in Exhibit 5)
24
Power of Attorney (included on signature page)