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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: center"><B>As filed with the Securities and Exchange
Commission on February 22, 2024</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0pt; text-align: right"><B>Registration No. 333-</B></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0pt; text-align: center"><B>UNITED STATES<BR>
SECURITIES AND EXCHANGE COMMISSION<BR>
Washington, D.C. 20549</B></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0pt; text-align: center"><B>FORM S-8<BR>
REGISTRATION STATEMENT<BR>
<I>UNDER<BR>
THE SECURITIES ACT OF 1933</I></B></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0; text-align: center"><B>GENMAB A/S<BR>
</B>(Exact name of registrant as specified in its charter)</P>

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    <P STYLE="font: 10pt/12pt Times New Roman, Times, Serif; margin: 15.15pt 4.5pt 0; text-align: center"><B>The Kingdom of Denmark</B></P>
    <P STYLE="font: 10pt/12pt Times New Roman, Times, Serif; margin: 0.3pt 4.5pt 25.3pt; text-align: center">(State or other jurisdiction
    of incorporation or organization)</P></TD>
    <TD>
    <P STYLE="font: 10pt/12pt Times New Roman, Times, Serif; margin: 0 4.3pt; text-align: center"><B>Carl Jacobsens Vej 30 </B></P>
    <P STYLE="font: 10pt/12pt Times New Roman, Times, Serif; margin: 0 4.3pt; text-align: center"><B>2500 Valby </B></P>
    <P STYLE="font: 10pt/12pt Times New Roman, Times, Serif; margin: 0 4.3pt; text-align: center"><B>Denmark</B></P>
    <P STYLE="font: 10pt/12pt Times New Roman, Times, Serif; margin: 0 4.5pt 4.65pt; text-align: center">(Address of Principal Executive<BR>
    Offices, including zip code)</P></TD>
    <TD>
    <P STYLE="font: 10pt/12pt Times New Roman, Times, Serif; margin: 15.15pt 4.5pt 0; text-align: center"><B>Not Applicable</B></P>
    <P STYLE="font: 10pt/12pt Times New Roman, Times, Serif; margin: 0.3pt 4.5pt 25.3pt; text-align: center">(I.R.S. Employer<BR>
    Identification No.)</P></TD></TR>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: center"><BR>
<B>Genmab A/S 2021 Restricted Stock Units Program<BR>
Genmab A/S 2021 Warrant Scheme<BR>
</B>(Full title of the plans)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: center"><B>Genmab US, Inc.<BR>
777 Scudders Mill Road<BR>
Plainsboro, NJ 08536<BR>
</B>(Name and address of agent for service)<BR>
<B>(609) 430-2481<BR>
</B>(Telephone number, including area code, of agent for service)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: center"><I>With a copy to:<BR>
</I><B>Doreen E. Lilienfeld, Esq.<BR>
Shearman &amp; Sterling LLP<BR>
599 Lexington Avenue<BR>
New York, NY 10022<BR>
(212) 848-4000</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt">Indicate by check mark whether the registrant is a large accelerated
filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of
&#8220;large accelerated filer,&#8221; &#8220;accelerated filer,&#8221; &#8220;smaller reporting company,&#8221; and &#8220;emerging growth
company&#8221; in Rule 12b-2 of the Exchange Act.</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
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    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt"><FONT STYLE="font-size: 10pt">Large accelerated filer</FONT></TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt"><FONT STYLE="font-family: Segoe UI Symbol,sans-serif; font-size: 10pt">&#9746;</FONT></TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt"><FONT STYLE="font-size: 10pt">Accelerated filer</FONT></TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt"><FONT STYLE="font-family: Segoe UI Symbol,sans-serif; font-size: 10pt">&#9744;</FONT></TD></TR>
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    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt"><FONT STYLE="font-size: 10pt">Non-accelerated filer</FONT></TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt"><FONT STYLE="font-family: Segoe UI Symbol,sans-serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt"><FONT STYLE="font-size: 10pt">Smaller reporting company</FONT></TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt"><FONT STYLE="font-family: Segoe UI Symbol,sans-serif; font-size: 10pt">&#9744;</FONT></TD></TR>
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    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt"><FONT STYLE="font-size: 10pt">Emerging growth company</FONT></TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt"><FONT STYLE="font-family: Segoe UI Symbol,sans-serif; font-size: 10pt">&#9744;</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt">If an emerging growth company, indicate by check mark if the registrant
has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant
to Section 7(a)(2)(B) of the Securities Act. <FONT STYLE="font-family: Segoe UI Symbol,sans-serif">&#10065;</FONT></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: center"><B>PART I<BR>
INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-indent: 0.5in">All information required by Part I of Form S-8
to be contained in the prospectus is omitted from this Registration Statement on form S-8 (the &#8220;Registration Statement&#8221;) in
accordance with Rule 428 under the Securities Act and the &#8220;Note&#8221; to Part I of Form S-8.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: center"><B>PART II<BR>
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</B></P>

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    <TD STYLE="width: 1in"><FONT STYLE="font-size: 10pt"><B>Item 3.</B></FONT></TD>
    <TD><FONT STYLE="font-size: 10pt"><B>Incorporation of Documents by Reference.</B></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-indent: 0.5in">The following documents filed with the Securities
and Exchange Commission (the &#8220;Commission&#8221;) are hereby incorporated by reference in this Registration Statement:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-indent: 0.5in">(a) The Registrant&#8217;s annual report on
Form 20-F <FONT STYLE="background-color: white">for the fiscal year ended December 31, 2023, </FONT>filed with the Commission on February
14, 2024.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-indent: 0.5in">(b) All other reports filed by the Registrant
pursuant to Section 13(a) or 15(d) of the Exchange Act, since the end of the fiscal year covered by the registration statement referred
to in (a) above (other than portions of those documents furnished or not otherwise deemed to be filed).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-indent: 0.5in">(c) The description of the Registrant&#8217;s
Ordinary Shares and American Depositary Shares incorporated by reference to Exhibit 2.3 to the Registrant&#8217;s annual report on Form
20-F filed with the Commission on March 29, 2021.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-indent: 0.5in">All documents filed by the Registrant subsequent
to the date hereof pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act and, to the extent specifically designated therein,
Reports of Foreign Private Issuer on Form 6-K furnished by the Registrant to the Commission that are identified in such forms as being
incorporated into this Registration Statement and prior to the filing of a post-effective amendment to this Registration Statement indicating
that all of the securities offered hereby have been sold or which deregisters all securities then remaining unsold, shall be deemed to
be incorporated by reference into this Registration Statement and to be part hereof from the date of filing such documents.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-indent: 0.5in">Any statement contained in a document incorporated
or deemed to be incorporated by reference herein shall be deemed to be modified or superseded for purposes of this Registration Statement
to the extent that a statement contained herein or in any other subsequently filed document which also is or is deemed to be incorporated
by reference herein modifies or supersedes such statement. Any such statement so modified or superseded shall not be deemed, except as
so modified or superseded, to constitute a part of this Registration Statement.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0pt"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0pt"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 1in; padding-bottom: 12pt"><FONT STYLE="font-size: 10pt"><B>Item 4.</B></FONT></TD>
    <TD STYLE="width: 85%; padding-bottom: 12pt"><FONT STYLE="font-size: 10pt"><B>Description of Securities.</B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt 0.5in">Not applicable</P>

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  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-bottom: 12pt; width: 1in"><FONT STYLE="font-size: 10pt"><B>Item 5.</B></FONT></TD>
    <TD STYLE="padding-bottom: 12pt"><FONT STYLE="font-size: 10pt"><B>Interests of Named Experts and Counsel.</B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt 0.5in">Not applicable</P>

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  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 1in; padding-bottom: 12pt"><FONT STYLE="font-size: 10pt"><B>Item 6.</B></FONT></TD>
    <TD STYLE="padding-bottom: 12pt"><FONT STYLE="font-size: 10pt"><B>Indemnification of Directors and Officers.</B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-indent: 0.5in">According to the Danish Companies Act, shareholders,
at the general meeting, are permitted to discharge the Registrant&#8217;s board members and registered managers from liability for any
particular financial year based on a resolution relating to the period covered by the financial statements for the previous financial
year. This discharge means that the shareholders will relieve such board members and registered managers from liability to the Registrant.
However, shareholders cannot discharge any claims by individual shareholders or other third parties. The discharge can be set aside in
case the general meeting prior to its decision to discharge was not presented with all reasonable information necessary for the general
meeting to assess the matter at hand. In addition, the Registrant provides its board members and registered managers with directors&#8217;
and officers&#8217; liability insurance.</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-bottom: 12pt; width: 1in"><FONT STYLE="font-size: 10pt"><B>Item 7.</B></FONT></TD>
    <TD STYLE="padding-bottom: 12pt"><FONT STYLE="font-size: 10pt"><B>Exemption from Registration Claimed.</B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt 0.5in">Not applicable.</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 1in; padding-bottom: 12pt"><FONT STYLE="font-size: 10pt"><B>Item 8.</B></FONT></TD>
    <TD STYLE="width: 85%; padding-bottom: 12pt"><FONT STYLE="font-size: 10pt"><B>Exhibits.</B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt 0.5in">The following exhibits are filed as part of this Registration
Statement:</P>

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  <TR STYLE="vertical-align: bottom">
    <TD STYLE="white-space: nowrap; padding-right: 6pt; padding-left: 6pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; border-bottom: black 0.5pt solid"><B>Exhibit Number </B></P></TD>
    <TD STYLE="white-space: nowrap; padding-right: 6pt; padding-left: 6pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; border-bottom: black 0.5pt solid"><B>Description of Document</B></P></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; padding-right: 6pt; padding-left: 6pt"><FONT STYLE="font-size: 10pt">4.1 </FONT></TD>
    <TD STYLE="padding-right: 6pt; padding-left: 6pt"><FONT STYLE="font-size: 10pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1434265/000155837024000654/tmb-20240131xex3d1.htm">English translation of the Articles of Association of Genmab A/S, as in effect on the date hereof, filed as Exhibit 3.1 to the Registrant&#8217;s Current Report on Form 6-K filed with the Commission on January 31, 2024 (File No. 001-38976)</A></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; padding-right: 6pt; padding-left: 6pt"><FONT STYLE="font-size: 10pt">4.2 </FONT></TD>
    <TD STYLE="padding-right: 6pt; padding-left: 6pt"><FONT STYLE="font-size: 10pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1434265/000094787121000269/ss193049_ex0402.htm">Genmab A/S 2021 Restricted Stock Units Program (incorporated by reference to Exhibit 4.2 to the Registrant&#8217;s Registration Statement on Form S-8, filed with the Commission on February 25, 2021 (File No. 333-253519))</A></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; padding-right: 6pt; padding-left: 6pt"><FONT STYLE="font-size: 10pt">5.1* </FONT></TD>
    <TD STYLE="padding-right: 6pt; padding-left: 6pt"><FONT STYLE="font-size: 10pt"><A HREF="ss3056390_ex0501.htm">Opinion of Kromann Reumert, with respect to the legality of the securities being registered</A></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; padding-right: 6pt; padding-left: 6pt"><FONT STYLE="font-size: 10pt">23.1* </FONT></TD>
    <TD STYLE="padding-right: 6pt; padding-left: 6pt"><FONT STYLE="font-size: 10pt"><A HREF="ss3056390_ex0501.htm">Consent of Kromann Reumert (included in the opinion filed as Exhibit 5.1)</A></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; padding-right: 6pt; padding-left: 6pt"><FONT STYLE="font-size: 10pt">23.2* </FONT></TD>
    <TD STYLE="padding-right: 6pt; padding-left: 6pt"><FONT STYLE="font-size: 10pt"><A HREF="ss3056390_ex2302.htm">Consent of PricewaterhouseCoopers Statsautoriseret Revisionspartnerselskab</A></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; padding-right: 6pt; padding-left: 6pt"><FONT STYLE="font-size: 10pt">24.1* </FONT></TD>
    <TD STYLE="padding-right: 6pt; padding-left: 6pt"><FONT STYLE="font-size: 10pt"><A HREF="#a_001">Limited Power of Attorney of the directors of the Registrant (contained in the signature pages hereto)</A></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; padding-right: 6pt; padding-left: 6pt"><FONT STYLE="font-size: 10pt">99.1 </FONT></TD>
    <TD STYLE="padding-right: 6pt; padding-left: 6pt"><FONT STYLE="font-size: 10pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1434265/000094787121000269/ss193049_ex9901.htm">Genmab A/S 2021 Warrant Scheme (incorporated by reference to Exhibit 99.1 to the Registrant&#8217;s Registration Statement on Form S-8, filed with the Commission on February 25, 2021 (File No. 333-253519))</A></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; padding-right: 6pt; padding-left: 6pt"><FONT STYLE="font-size: 10pt">107*</FONT></TD>
    <TD STYLE="padding-right: 6pt; padding-left: 6pt"><FONT STYLE="font-size: 10pt"><A HREF="ss3056390_ex0107.htm">Filing Fee Table</A></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;<B>_____________ </B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt 0.25in; text-indent: -0.25in"><B>* </B>Filed herewith.</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 1in; padding-bottom: 12pt"><FONT STYLE="font-size: 10pt"><B>Item 9.</B></FONT></TD>
    <TD STYLE="width: 84%; padding-bottom: 12pt"><FONT STYLE="font-size: 10pt"><B>Undertakings.</B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-indent: 0.5in">(a) The undersigned Registrant hereby undertakes:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt 0.5in; text-indent: 0.5in">(1) To file, during any period in which
offers or sales are being made of securities registered hereby, a post-effective amendment to this Registration Statement which shall
include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement or any
material change to such information in the Registration Statement:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 11pt 0.5in; text-align: justify; text-indent: 1in">(i) To include any
prospectus required by Section 10(a)(3) of the Securities Act;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-right: 0; margin-bottom: 0pt; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-right: 0; margin-bottom: 0pt; text-align: justify"></P>

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    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-right: 0; margin-bottom: 0pt; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 11pt 0.5in; text-align: justify; text-indent: 1in"><FONT STYLE="font-size: 10pt">(ii)
To reflect in the prospectus any facts or events arising after the effective date of this Registration Statement (or the most recent post-effective
amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in this Registration
Statement; and</FONT>&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 11pt 0.5in; text-align: justify; text-indent: 1in">(iii) To include any
material information with respect to the plan of distribution not previously disclosed in this Registration Statement or any material
change to such information in this Registration Statement;&nbsp;<I>provided</I>,&nbsp;<I>however</I>, that paragraphs (1)(i) and (1)(ii)
do not apply if the information required to be included in a post-effective amendment by those paragraphs is contained in periodic reports
filed with or furnished to the Commission by the Registrant pursuant to Section 13 or 15(d) of the Exchange Act that are incorporated
by reference in this Registration Statement.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt 0.5in; text-indent: 0.5in">(2) That, for the purpose of determining
any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating
to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial <I>bona fide </I>offering
thereof; and</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt 0.5in; text-indent: 0.5in">(3) To remove from registration by means
of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-indent: 0.5in"><FONT STYLE="font-size: 10pt">(b) The undersigned
Registrant hereby further undertakes that, for purposes of determining any liability under the Securities Act, each filing of the Registrant&#8217;s
annual report pursuant to Section 13(a) or 15(d) of the Exchange Act that is incorporated by reference in the Registration Statement shall
be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time
shall be deemed to be the initial <I>bona fide </I>offering thereof.</FONT>&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-indent: 0.5in"><FONT STYLE="font-size: 10pt">(c) Insofar as
indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the
Registrant pursuant to the foregoing provisions, or otherwise, the Registrant has been advised that in the opinion of the Commission such
indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim
for indemnification against such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer
or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer
or controlling person in connection with the securities being registered, the Registrant will, unless in the opinion of its counsel the
matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification
by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.</FONT>&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: center"><B>SIGNATURES</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-indent: 0.5in">Pursuant to the requirements of the Securities
Act, the Registrant certifies that it has reasonable grounds to believe it meets all of the requirements for filing on Form S-8 and has
duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in Utrecht, the Netherlands
on February 22, 2024.</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="padding-right: 5.65pt; padding-left: 5.65pt"><FONT STYLE="font-size: 10pt"><B>Genmab A/S</B></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="padding-right: 5.65pt; padding-left: 5.65pt"><FONT STYLE="font-size: 10pt">(Registrant)</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt"><FONT STYLE="font-size: 10pt">By: </FONT></TD>
    <TD STYLE="border-bottom: black 1pt solid; padding-right: 5.65pt; padding-left: 5.65pt"><FONT STYLE="font-size: 10pt">/s/ Jan G. J. van de Winkel</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt"><FONT STYLE="font-size: 10pt">Jan G. J. van de Winkel</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt"><FONT STYLE="font-size: 10pt">President &amp; Chief Executive Officer</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0pt; text-align: left"></P>

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    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0pt; text-align: left"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: center"><B><A NAME="a_001" TITLE="limitedpowerofattorney"></A>Limited Power of Attorney</B><BR>
(Form S-8)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-indent: 0.5in">KNOW ALL PERSONS BY THESE PRESENTS, that each
of the undersigned officers and directors of the Registrant does hereby constitute and appoint each of Birgitte Stephensen and Anthony
Pagano as his or her true and lawful attorney-in-fact and agent, to do or cause to be done any and all acts and things and to execute
any and all instruments and documents which said attorneys-in-fact and agents may deem advisable or necessary to enable the Company to
comply with the Securities Act, and any rules, regulations and requirements of the Commission in respect thereof, in connection with the
registration of the securities or deferred compensation obligations of the Registrant being registered on the Registration Statement (the
&#8220;Securities&#8221;), including specifically, but without limiting the generality of the foregoing, power and authority to sign,
in the name and on behalf of each of the undersigned, the Registration Statement, any other registration statement under Rule 462(b) of
the Securities Act, or another appropriate form in respect of the registration of the Securities, and any and all amendments thereto,
including post-effective amendments, and any instruments, contracts, documents or other writings of which the originals or copies thereof
are to be filed as a part of, or in connection with, any such registration statement or any other appropriate form or amendments thereto,
and to file or cause to be filed the same with the Commission, and to effect any and all applications and other instruments in the name
and on behalf of each of the undersigned which said attorneys-in-fact and agents deem advisable in order to qualify or register the Securities
under the securities laws of any of the several states or other jurisdictions; and each of the undersigned does hereby ratify all that
said attorneys-in-fact and agents shall do or cause to be done by virtue thereof. Each attorney-in-fact and agent is hereby granted full
power of substitution and revocation with respect hereto.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-indent: 0.5in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt"><FONT STYLE="font-size: 10pt"><B>Signatures</B></FONT></TD>
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt"><FONT STYLE="font-size: 10pt"><B>Title</B></FONT></TD>
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt"><FONT STYLE="font-size: 10pt"><B>Date</B></FONT></TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; border-bottom: Black 1pt solid"><FONT STYLE="font-size: 10pt">/s/ Jan G. J. van de Winkel</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; text-align: center">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; line-height: 12pt"><FONT STYLE="font-size: 10pt">Jan G. J. van de Winkel</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; text-align: center; line-height: 12pt"><FONT STYLE="font-size: 10pt">President &amp; Chief Executive Officer </FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; text-align: center; line-height: 12pt"><FONT STYLE="font-size: 10pt">February 22, 2024</FONT></TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; text-align: center; line-height: 12pt"><FONT STYLE="font-size: 10pt">(Principal Executive Officer)</FONT></TD>
    <TD STYLE="white-space: nowrap; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; text-align: center; line-height: 12pt">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; border-bottom: Black 1pt solid"><FONT STYLE="font-size: 10pt">/s/ Anthony Pagano</FONT></TD>
    <TD STYLE="white-space: nowrap; text-align: center">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; line-height: 12pt"><FONT STYLE="font-size: 10pt">Anthony Pagano</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; text-align: center; line-height: 12pt"><FONT STYLE="font-size: 10pt">Executive Vice President &amp; Chief Financial Officer</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; text-align: center; line-height: 12pt"><FONT STYLE="font-size: 10pt">February 22, 2024</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt"><FONT STYLE="font-size: 10pt">(Principal Financial Officer and Principal Accounting</FONT></TD>
    <TD STYLE="white-space: nowrap; text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt"><FONT STYLE="font-size: 10pt">Officer)</FONT></TD>
    <TD STYLE="white-space: nowrap; text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; border-bottom: Black 1pt solid"><FONT STYLE="font-size: 10pt">/s/ Deirdre P. Connelly</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; text-align: center">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; line-height: 12pt"><FONT STYLE="font-size: 10pt">Deirdre P. Connelly</FONT></TD>
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt"><FONT STYLE="font-size: 10pt">Chair of the Board of Directors</FONT></TD>
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt"><FONT STYLE="font-size: 10pt">February 22, 2024</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; line-height: 12pt">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; line-height: 12pt">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; border-bottom: Black 1pt solid"><FONT STYLE="font-size: 10pt">/s/ Pernille Erenbjerg</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; text-align: center">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; line-height: 12pt"><FONT STYLE="font-size: 10pt">Pernille Erenbjerg</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; text-align: center; line-height: 12pt"><FONT STYLE="font-size: 10pt">Deputy Chair of the Board of Directors</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; text-align: center; line-height: 12pt"><FONT STYLE="font-size: 10pt">February 22, 2024</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; line-height: 12pt">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; border-bottom: Black 1pt solid"><FONT STYLE="font-size: 10pt">/s/ Anders Gersel Pedersen</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; text-align: center">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; line-height: 12pt"><FONT STYLE="font-size: 10pt">Anders Gersel Pedersen</FONT></TD>
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt"><FONT STYLE="font-size: 10pt">Director</FONT></TD>
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt"><FONT STYLE="font-size: 10pt">February 22, 2024</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; line-height: 12pt">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; text-align: center; line-height: 12pt">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="border-bottom: Black 1pt solid"><FONT STYLE="font-size: 10pt">/s/ Paolo Paoletti</FONT></TD>
    <TD STYLE="vertical-align: top; text-align: center">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD><FONT STYLE="font-size: 10pt">Paolo Paoletti</FONT></TD>
    <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt">Director</FONT></TD>
    <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt">February 22, 2024</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD STYLE="text-align: center">&nbsp;</TD>
    <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="border-bottom: Black 1pt solid"><FONT STYLE="font-size: 10pt">/s/ Rolf Hoffman</FONT></TD>
    <TD STYLE="vertical-align: top; text-align: center">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD><FONT STYLE="font-size: 10pt">Rolf Hoffman</FONT></TD>
    <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt">Director</FONT></TD>
    <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt">February 22, 2024</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD STYLE="text-align: center">&nbsp;</TD>
    <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="border-bottom: Black 1pt solid"><FONT STYLE="font-size: 10pt">/s/ Elizabeth O&#8217;Farrell</FONT></TD>
    <TD STYLE="vertical-align: top; text-align: center">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD><FONT STYLE="font-size: 10pt">Elizabeth O&#8217;Farrell</FONT></TD>
    <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt">Director</FONT></TD>
    <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt">February 22, 2024</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD STYLE="text-align: center">&nbsp;</TD>
    <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="border-bottom: Black 1pt solid"><FONT STYLE="font-size: 10pt">/s/ Mijke Zachariasse</FONT></TD>
    <TD STYLE="vertical-align: top; text-align: center">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD><FONT STYLE="font-size: 10pt">Mijke Zachariasse</FONT></TD>
    <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt">Director</FONT></TD>
    <TD STYLE="text-align: center"><FONT STYLE="font-size: 10pt">February 22, 2024</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD STYLE="text-align: center">&nbsp;</TD>
    <TD STYLE="text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="border-bottom: Black 1pt solid"><FONT STYLE="font-size: 10pt">/s/ Takahiro Hamatani</FONT></TD>
    <TD STYLE="vertical-align: top; text-align: center">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD><FONT STYLE="font-size: 10pt">Takahiro Hamatani</FONT></TD>
    <TD STYLE="vertical-align: top; text-align: center"><FONT STYLE="font-size: 10pt">Director</FONT></TD>
    <TD STYLE="vertical-align: top; text-align: center"><FONT STYLE="font-size: 10pt">February 22, 2024</FONT></TD></TR>
  <TR>
    <TD>&nbsp;</TD>
    <TD STYLE="vertical-align: top; text-align: center">&nbsp;</TD>
    <TD STYLE="vertical-align: top; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="border-bottom: Black 1pt solid"><FONT STYLE="font-size: 10pt">/s/ Martin Schultz</FONT></TD>
    <TD STYLE="vertical-align: top; text-align: center">&nbsp;</TD>
    <TD STYLE="vertical-align: top; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD><FONT STYLE="font-size: 10pt">Martin Schultz</FONT></TD>
    <TD STYLE="vertical-align: top; text-align: center"><FONT STYLE="font-size: 10pt">Director</FONT></TD>
    <TD STYLE="vertical-align: top; text-align: center"><FONT STYLE="font-size: 10pt">February 22, 2024</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0pt"></P>

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    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-indent: 0.5in"><FONT STYLE="font-size: 10pt">IN WITNESS WHEREOF,
each of the undersigned has executed this Limited Power of Attorney as of and on the dates indicated below.</FONT>&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-indent: 0.5in">Pursuant to the requirements of the Securities
Act, this Registration Statement has been signed below by the following persons in the capacities and on the dates indicated.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: center"><B>Signature of Authorized U.S. Representative
of Registrant</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-indent: 0.5in">Pursuant to the requirements of the Securities
Act, the undersigned, the duly authorized representative in the United States of the Registrant, has signed this Registration Statement
on February 22, 2024.</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt"><FONT STYLE="font-size: 10pt">By: </FONT></TD>
    <TD STYLE="border-bottom: black 1pt solid; padding-right: 5.65pt; padding-left: 5.65pt"><FONT STYLE="font-size: 10pt">/s/ Anthony Pagano</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt"><FONT STYLE="font-size: 10pt">Name: Anthony Pagano</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt">&nbsp;</TD>
    <TD STYLE="padding-right: 5.65pt; padding-left: 5.65pt"><FONT STYLE="font-size: 10pt">Title: Executive Vice President and Chief Financial Officer </FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

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[{"type": "S-8", "sequence": "1", "filename": "ss3056390_s8.htm", "description": "REGISTRATION STATEMENT", "secsgml_size_bytes": 48061}]
{"company-data": {"conformed-name": "GENMAB A/S", "cik": "0001434265", "assigned-sic": "2834", "organization-name": "03 Life Sciences", "irs-number": "000000000"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-277273", "film-number": "24665269"}, "business-address": {"street1": "TOLDBODGADE 33", "city": "1253 COPENHAGEN K", "state": "G7", "zip": "00000"}, "mail-address": {"street1": "TOLDBODGADE 33", "city": "1253 COPENHAGEN K", "state": "G7", "zip": "00000"}}
As filed with the Securities and Exchange
Commission on February 22, 2024
Registration No. 333-
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-8
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
GENMAB A/S
(Exact name of registrant as specified in its charter)
The Kingdom of Denmark
(State or other jurisdiction
    of incorporation or organization)
Carl Jacobsens Vej 30
2500 Valby
Denmark
(Address of Principal Executive
Offices, including zip code)
Not Applicable
(I.R.S. Employer
Identification No.)
Genmab A/S 2021 Restricted Stock Units Program
Genmab A/S 2021 Warrant Scheme
(Full title of the plans)
Genmab US, Inc.
777 Scudders Mill Road
Plainsboro, NJ 08536
(Name and address of agent for service)
(609) 430-2481
(Telephone number, including area code, of agent for service)
With a copy to:
Doreen E. Lilienfeld, Esq.
Shearman & Sterling LLP
599 Lexington Avenue
New York, NY 10022
(212) 848-4000
Indicate by check mark whether the registrant is a large accelerated
filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of
"large accelerated filer," "accelerated filer," "smaller reporting company," and "emerging growth
company" in Rule 12b-2 of the Exchange Act.
Large accelerated filer
☒
Accelerated filer
☐
Non-accelerated filer
☐
Smaller reporting company
☐
Emerging growth company
☐
If an emerging growth company, indicate by check mark if the registrant
has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant
to Section 7(a)(2)(B) of the Securities Act.
❑
PART I
INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS
All information required by Part I of Form S-8
to be contained in the prospectus is omitted from this Registration Statement on form S-8 (the "Registration Statement") in
accordance with Rule 428 under the Securities Act and the "Note" to Part I of Form S-8.
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 3.
Incorporation of Documents by Reference.
The following documents filed with the Securities
and Exchange Commission (the "Commission") are hereby incorporated by reference in this Registration Statement:
(a) The Registrant's annual report on
Form 20-F
for the fiscal year ended December 31, 2023,
filed with the Commission on February
14, 2024.
(b) All other reports filed by the Registrant
pursuant to Section 13(a) or 15(d) of the Exchange Act, since the end of the fiscal year covered by the registration statement referred
to in (a) above (other than portions of those documents furnished or not otherwise deemed to be filed).
(c) The description of the Registrant's
Ordinary Shares and American Depositary Shares incorporated by reference to Exhibit 2.3 to the Registrant's annual report on Form
20-F filed with the Commission on March 29, 2021.
All documents filed by the Registrant subsequent
to the date hereof pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act and, to the extent specifically designated therein,
Reports of Foreign Private Issuer on Form 6-K furnished by the Registrant to the Commission that are identified in such forms as being
incorporated into this Registration Statement and prior to the filing of a post-effective amendment to this Registration Statement indicating
that all of the securities offered hereby have been sold or which deregisters all securities then remaining unsold, shall be deemed to
be incorporated by reference into this Registration Statement and to be part hereof from the date of filing such documents.
Any statement contained in a document incorporated
or deemed to be incorporated by reference herein shall be deemed to be modified or superseded for purposes of this Registration Statement
to the extent that a statement contained herein or in any other subsequently filed document which also is or is deemed to be incorporated
by reference herein modifies or supersedes such statement. Any such statement so modified or superseded shall not be deemed, except as
so modified or superseded, to constitute a part of this Registration Statement.
Item 4.
Description of Securities.
Not applicable
Item 5.
Interests of Named Experts and Counsel.
Not applicable
Item 6.
Indemnification of Directors and Officers.
According to the Danish Companies Act, shareholders,
at the general meeting, are permitted to discharge the Registrant's board members and registered managers from liability for any
particular financial year based on a resolution relating to the period covered by the financial statements for the previous financial
year. This discharge means that the shareholders will relieve such board members and registered managers from liability to the Registrant.
However, shareholders cannot discharge any claims by individual shareholders or other third parties. The discharge can be set aside in
case the general meeting prior to its decision to discharge was not presented with all reasonable information necessary for the general
meeting to assess the matter at hand. In addition, the Registrant provides its board members and registered managers with directors'
and officers' liability insurance.
Item 7.
Exemption from Registration Claimed.
Not applicable.
Item 8.
Exhibits.
The following exhibits are filed as part of this Registration
Statement:
Exhibit Number
Description of Document
4.1
English translation of the Articles of Association of Genmab A/S, as in effect on the date hereof, filed as Exhibit 3.1 to the Registrant's Current Report on Form 6-K filed with the Commission on January 31, 2024 (File No. 001-38976)
4.2
Genmab A/S 2021 Restricted Stock Units Program (incorporated by reference to Exhibit 4.2 to the Registrant's Registration Statement on Form S-8, filed with the Commission on February 25, 2021 (File No. 333-253519))
5.1*
Opinion of Kromann Reumert, with respect to the legality of the securities being registered
23.1*
Consent of Kromann Reumert (included in the opinion filed as Exhibit 5.1)
23.2*
Consent of PricewaterhouseCoopers Statsautoriseret Revisionspartnerselskab
24.1*
Limited Power of Attorney of the directors of the Registrant (contained in the signature pages hereto)
99.1
Genmab A/S 2021 Warrant Scheme (incorporated by reference to Exhibit 99.1 to the Registrant's Registration Statement on Form S-8, filed with the Commission on February 25, 2021 (File No. 333-253519))
107*
Filing Fee Table
_____________
*
Filed herewith.
Item 9.
Undertakings.
(a) The undersigned Registrant hereby undertakes:
(1) To file, during any period in which
offers or sales are being made of securities registered hereby, a post-effective amendment to this Registration Statement which shall
include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement or any
material change to such information in the Registration Statement:
(i) To include any
prospectus required by Section 10(a)(3) of the Securities Act;
(ii)
To reflect in the prospectus any facts or events arising after the effective date of this Registration Statement (or the most recent post-effective
amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in this Registration
Statement; and
(iii) To include any
material information with respect to the plan of distribution not previously disclosed in this Registration Statement or any material
change to such information in this Registration Statement;
provided
,
however
, that paragraphs (1)(i) and (1)(ii)
do not apply if the information required to be included in a post-effective amendment by those paragraphs is contained in periodic reports
filed with or furnished to the Commission by the Registrant pursuant to Section 13 or 15(d) of the Exchange Act that are incorporated
by reference in this Registration Statement.
(2) That, for the purpose of determining
any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating
to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial
bona fide
offering
thereof; and
(3) To remove from registration by means
of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.
(b) The undersigned
Registrant hereby further undertakes that, for purposes of determining any liability under the Securities Act, each filing of the Registrant's
annual report pursuant to Section 13(a) or 15(d) of the Exchange Act that is incorporated by reference in the Registration Statement shall
be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time
shall be deemed to be the initial
bona fide
offering thereof.
(c) Insofar as
indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the
Registrant pursuant to the foregoing provisions, or otherwise, the Registrant has been advised that in the opinion of the Commission such
indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim
for indemnification against such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer
or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer
or controlling person in connection with the securities being registered, the Registrant will, unless in the opinion of its counsel the
matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification
by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.
SIGNATURES
Pursuant to the requirements of the Securities
Act, the Registrant certifies that it has reasonable grounds to believe it meets all of the requirements for filing on Form S-8 and has
duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in Utrecht, the Netherlands
on February 22, 2024.
Genmab A/S
(Registrant)
By:
/s/ Jan G. J. van de Winkel
Jan G. J. van de Winkel
President & Chief Executive Officer
Limited Power of Attorney
(Form S-8)
KNOW ALL PERSONS BY THESE PRESENTS, that each
of the undersigned officers and directors of the Registrant does hereby constitute and appoint each of Birgitte Stephensen and Anthony
Pagano as his or her true and lawful attorney-in-fact and agent, to do or cause to be done any and all acts and things and to execute
any and all instruments and documents which said attorneys-in-fact and agents may deem advisable or necessary to enable the Company to
comply with the Securities Act, and any rules, regulations and requirements of the Commission in respect thereof, in connection with the
registration of the securities or deferred compensation obligations of the Registrant being registered on the Registration Statement (the
"Securities"), including specifically, but without limiting the generality of the foregoing, power and authority to sign,
in the name and on behalf of each of the undersigned, the Registration Statement, any other registration statement under Rule 462(b) of
the Securities Act, or another appropriate form in respect of the registration of the Securities, and any and all amendments thereto,
including post-effective amendments, and any instruments, contracts, documents or other writings of which the originals or copies thereof
are to be filed as a part of, or in connection with, any such registration statement or any other appropriate form or amendments thereto,
and to file or cause to be filed the same with the Commission, and to effect any and all applications and other instruments in the name
and on behalf of each of the undersigned which said attorneys-in-fact and agents deem advisable in order to qualify or register the Securities
under the securities laws of any of the several states or other jurisdictions; and each of the undersigned does hereby ratify all that
said attorneys-in-fact and agents shall do or cause to be done by virtue thereof. Each attorney-in-fact and agent is hereby granted full
power of substitution and revocation with respect hereto.
Signatures
Title
Date
/s/ Jan G. J. van de Winkel
Jan G. J. van de Winkel
President & Chief Executive Officer
February 22, 2024
(Principal Executive Officer)
/s/ Anthony Pagano
Anthony Pagano
Executive Vice President & Chief Financial Officer
February 22, 2024
(Principal Financial Officer and Principal Accounting
Officer)
/s/ Deirdre P. Connelly
Deirdre P. Connelly
Chair of the Board of Directors
February 22, 2024
/s/ Pernille Erenbjerg
Pernille Erenbjerg
Deputy Chair of the Board of Directors
February 22, 2024
/s/ Anders Gersel Pedersen
Anders Gersel Pedersen
Director
February 22, 2024
/s/ Paolo Paoletti
Paolo Paoletti
Director
February 22, 2024
/s/ Rolf Hoffman
Rolf Hoffman
Director
February 22, 2024
/s/ Elizabeth O'Farrell
Elizabeth O'Farrell
Director
February 22, 2024
/s/ Mijke Zachariasse
Mijke Zachariasse
Director
February 22, 2024
/s/ Takahiro Hamatani
Takahiro Hamatani
Director
February 22, 2024
/s/ Martin Schultz
Martin Schultz
Director
February 22, 2024
IN WITNESS WHEREOF,
each of the undersigned has executed this Limited Power of Attorney as of and on the dates indicated below.
Pursuant to the requirements of the Securities
Act, this Registration Statement has been signed below by the following persons in the capacities and on the dates indicated.
Signature of Authorized U.S. Representative
of Registrant
Pursuant to the requirements of the Securities
Act, the undersigned, the duly authorized representative in the United States of the Registrant, has signed this Registration Statement
on February 22, 2024.
By:
/s/ Anthony Pagano
Name: Anthony Pagano
Title: Executive Vice President and Chief Financial Officer