<html>
  <head>
    <title></title>
    <!-- Licensed to: National Instruments Corporation
         Document created using Broadridge PROfile 22.7.2.5063
         Copyright 1995 - 2022 Broadridge -->
  </head>
<body bgcolor="#ffffff" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; text-align: left; color: #000000;">
  <div>
    <div style="text-align: center; line-height: 11.4pt; font-weight: bold;">As filed with the Securities and Exchange Commission on August 5, 2022</div>
    <div style="line-height: 11.4pt;"><br style="line-height: 11.4pt;">
    </div>
    <div style="text-align: right; line-height: 11.4pt; margin-bottom: 10pt; font-weight: bold;">Registration No. 333-_____</div>
    <table cellspacing="0" cellpadding="0" id="ze4fe7d393a514dd7be15080f6c8f8ce8" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

        <tr>
          <td style="width: 99.94%; vertical-align: bottom; border-top: #000000 4px double;" colspan="3">
            <div style="text-align: center; line-height: 19.4pt; font-size: 14pt; font-weight: bold;">UNITED STATES</div>
            <div style="text-align: center; line-height: 19.4pt; font-size: 14pt; font-weight: bold;">SECURITIES AND EXCHANGE COMMISSION</div>
          </td>
          <td style="width: 0.06%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 99.94%; vertical-align: bottom;" colspan="3">
            <div style="text-align: center; line-height: 12.55pt; font-weight: bold;">Washington, D.C. 20549</div>
          </td>
          <td style="width: 0.06%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 99.94%; vertical-align: bottom;" colspan="3">&#160;</td>
          <td style="width: 0.06%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 99.94%; vertical-align: bottom;" colspan="3">
            <div style="text-align: center; line-height: 19.4pt; font-size: 14pt;"><font style="font-weight: bold;">FORM S</font>&#8209;<font style="font-weight: bold;">8</font></div>
          </td>
          <td style="width: 0.06%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 99.94%; vertical-align: bottom;" colspan="3">
            <div style="text-align: center; line-height: 17.1pt; font-size: 14pt; font-weight: bold;">REGISTRATION STATEMENT</div>
          </td>
          <td style="width: 0.06%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 99.94%; vertical-align: bottom;" colspan="3">
            <div style="text-align: center; line-height: 15.05pt; font-style: italic; font-weight: bold;">Under</div>
            <div style="text-align: center; line-height: 18.05pt; font-style: italic; font-weight: bold;">The Securities Act of 1933</div>
          </td>
          <td style="width: 0.06%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 99.94%; vertical-align: bottom;" colspan="3">&#160;</td>
          <td style="width: 0.06%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 99.94%; vertical-align: bottom;" colspan="3">
            <div style="text-align: center; line-height: 19.4pt; font-size: 14pt; font-weight: bold;">NATIONAL INSTRUMENTS CORPORATION</div>
          </td>
          <td style="width: 0.06%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 99.94%; vertical-align: bottom;" colspan="3">
            <div style="text-align: center; line-height: 9.1pt; font-size: 8pt; font-weight: bold;">(Exact name of registrant as specified in its charter)</div>
          </td>
          <td style="width: 0.06%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 99.94%; vertical-align: bottom;" colspan="3">&#160;</td>
          <td style="width: 0.06%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 24.41%; vertical-align: bottom;">
            <div style="text-align: center; line-height: 12.55pt; font-weight: bold;">Delaware</div>
          </td>
          <td style="width: 49.69%; vertical-align: bottom;">&#160;</td>
          <td style="width: 25.9%; vertical-align: bottom;" colspan="2">
            <div style="text-align: center; line-height: 12.55pt; font-weight: bold;">74-1871327</div>
          </td>
        </tr>
        <tr>
          <td style="width: 24.41%; vertical-align: bottom;">
            <div style="text-align: center; line-height: 10.95pt; font-size: 8pt; font-weight: bold;">(State or other jurisdiction of</div>
            <div style="text-align: center; line-height: 13.15pt; font-size: 8pt; font-weight: bold;">incorporation or organization)</div>
          </td>
          <td style="width: 49.69%; vertical-align: bottom;">&#160;</td>
          <td style="width: 25.9%; vertical-align: bottom;" colspan="2">
            <div style="text-align: center; line-height: 13.15pt; font-size: 8pt; font-weight: bold;">(I.R.S. Employer</div>
            <div style="text-align: center; line-height: 13.15pt; font-size: 8pt; font-weight: bold;">Identification Number)</div>
          </td>
        </tr>
        <tr>
          <td style="width: 24.41%; vertical-align: bottom;">&#160;</td>
          <td style="width: 49.69%; vertical-align: bottom;">
            <div style="text-align: center; line-height: 18.05pt; font-weight: bold;">11500 North MoPac Expressway</div>
            <div style="text-align: center; line-height: 18.05pt; font-weight: bold;">Austin, Texas 78759</div>
          </td>
          <td style="width: 25.9%; vertical-align: bottom;" colspan="2">&#160;</td>
        </tr>
        <tr>
          <td style="width: 99.94%; vertical-align: bottom;" colspan="3">
            <div style="text-align: center; line-height: 9.1pt; font-size: 8pt; font-weight: bold;">(Address, including zip code, of registrant&#8217;s principal executive offices)</div>
          </td>
          <td style="width: 0.06%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 99.94%; vertical-align: bottom;" colspan="3">&#160;</td>
          <td style="width: 0.06%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 24.41%; vertical-align: bottom;">&#160;</td>
          <td style="width: 49.69%; vertical-align: bottom;">
            <div style="text-align: center; line-height: 12.55pt;"><font style="font-weight: bold;">National Instruments Corporation 2022 Equity Incentive Plan<br>
              </font></div>
          </td>
          <td style="width: 25.9%; vertical-align: bottom;" colspan="2">&#160;</td>
        </tr>
        <tr>
          <td style="width: 24.41%; vertical-align: bottom;">&#160;</td>
          <td style="width: 49.69%; vertical-align: bottom;">
            <div style="text-align: center; line-height: 12.55pt; font-weight: bold;">National Instruments Corporation 1994 Employee Stock Purchase Plan</div>
          </td>
          <td style="width: 25.9%; vertical-align: bottom;" colspan="2">&#160;</td>
        </tr>
        <tr>
          <td style="width: 99.94%; vertical-align: bottom;" colspan="3">
            <div style="text-align: center; line-height: 9.1pt; font-size: 8pt; font-weight: bold;">(Full title of the Plan)</div>
          </td>
          <td style="width: 0.06%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 99.94%; vertical-align: bottom;" colspan="3">&#160;</td>
          <td style="width: 0.06%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 99.94%; vertical-align: bottom;" colspan="3">
            <div style="text-align: center; line-height: 15.05pt; font-weight: bold;">R. Eddie Dixon, Jr.</div>
            <div style="text-align: center; line-height: 18.05pt; font-weight: bold;">Senior Vice President, Chief Legal Officer and Secretary</div>
            <div style="text-align: center; line-height: 18.05pt; font-weight: bold;">National Instruments Corporation</div>
            <div style="text-align: center; line-height: 18.05pt; font-weight: bold;">11500 North Mopac Expressway</div>
            <div style="text-align: center; line-height: 18.05pt; font-weight: bold;">Austin, Texas 78759</div>
            <div style="text-align: center; line-height: 18.05pt; font-weight: bold;">(512) 683-0100</div>
          </td>
          <td style="width: 0.06%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 99.94%; vertical-align: bottom;" colspan="3">
            <div style="text-align: center; line-height: 9.1pt; font-size: 8pt; font-weight: bold;">(Name, address, and telephone number, including area code, of agent for service)</div>
          </td>
          <td style="width: 0.06%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 99.94%; vertical-align: bottom;" colspan="3">&#160;</td>
          <td style="width: 0.06%; vertical-align: top;">&#160;</td>
        </tr>

    </table>
    <div style="line-height: 14.4pt;">
      <div style="text-align: justify; text-indent: 36pt; line-height: 14.75pt;">Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth
        company. See the definitions of "large accelerated filer," "accelerated filer," "smaller reporting company" and "emerging growth company" in Rule 12b-2 of the Exchange Act. (Check one):</div>
    </div>
    <table cellspacing="0" cellpadding="0" id="z3c3afc4c96834de0a283bf636d475e30" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

        <tr>
          <td style="width: 100%; vertical-align: middle;" colspan="4">&#160;</td>
        </tr>
        <tr>
          <td style="width: 40.5%; vertical-align: middle;">&#160;</td>
          <td style="width: 5.22%; vertical-align: middle;">&#160;</td>
          <td style="width: 49.05%; vertical-align: middle;">&#160;</td>
          <td style="width: 5.22%; vertical-align: middle;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 40.5%; vertical-align: bottom;">
            <div style="line-height: 10.25pt;">Large accelerated filer</div>
          </td>
          <td style="width: 5.22%; vertical-align: bottom;">
            <div style="text-align: center; line-height: 10.25pt;">&#9746;</div>
          </td>
          <td style="width: 49.05%; vertical-align: bottom;">
            <div style="line-height: 10.25pt;">Accelerated filer</div>
          </td>
          <td style="width: 5.22%; vertical-align: bottom;">
            <div style="text-align: center; line-height: 10.25pt;">&#9744;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 40.5%; vertical-align: bottom;">
            <div style="line-height: 10.25pt;">Non-accelerated filer</div>
          </td>
          <td style="width: 5.22%; vertical-align: bottom;">
            <div style="text-align: center; line-height: 10.25pt;">&#9744;</div>
          </td>
          <td style="width: 49.05%; vertical-align: bottom;">
            <div style="line-height: 10.25pt;">Smaller reporting company</div>
          </td>
          <td style="width: 5.22%; vertical-align: bottom;">
            <div style="text-align: center; line-height: 10.25pt;">&#9744;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 40.5%; vertical-align: bottom;">
            <div style="line-height: 11.4pt;">&#160;</div>
          </td>
          <td style="width: 5.22%; vertical-align: bottom;">
            <div style="line-height: 11.4pt;">&#160;</div>
          </td>
          <td style="width: 49.05%; vertical-align: bottom;">
            <div style="line-height: 14.4pt;">
              <div style="line-height: 10.25pt;">Emerging growth company</div>
            </div>
          </td>
          <td style="width: 5.22%; vertical-align: bottom;">
            <div style="text-align: center; line-height: 10.25pt;">&#9744;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 14.4pt;">
      <div style="text-align: justify; text-indent: 36pt; line-height: 16.4pt;">If an emerging growth company, indicate by checkmark if the registrant has elected not to use the extended transition period for complying with any new or revised financial
        accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. <font style="font-family: 'Segoe UI Symbol', sans-serif;">&#9744;</font></div>
    </div>
    <div id="DSPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
      <div id="DSPFPageBreak" style="page-break-after:always;">
        <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 1px; color: #AAAAAA; background-color: #AAAAAA; clear: both;"></div>
    </div>
    <!--PROfilePageNumberReset%Num%1%%%-->
    <div style="margin: 12pt 0px 0px; line-height: normal; font-weight: bold; text-align: center;">EXPLANATORY NOTE</div>
    <div style="margin: 12pt 0px 0px; line-height: normal; text-align: justify; text-indent: 36pt;">National Instruments Corporation (the &#8220;Registrant&#8221; or &#8220;Company&#8221;) is filing this registration statement to register the issuance of 6,123,921 shares of its
      common stock, $0.01 par value per share (the &#8220;Common Stock&#8221;), reserved under the National Instruments Corporation 2022 Equity Incentive Plan (the &#8220;2022 Equity Incentive Plan&#8221;) and an additional 3,000,000 shares of Common Stock under the National
      Instruments Corporation 1994 Employee Stock Purchase Plan (the &#8220;ESPP&#8221;). The 2022 Equity Incentive Plan and additional 3,000,000 shares of Common Stock under the ESPP were described in the Company&#8217;s definitive proxy statement, filed with the United
      States Securities and Exchange Commission (the &#8220;Commission&#8221;) on March&#160;28, 2022, and were approved by the Company&#8217;s shareholders on May 10, 2022.&#160;The number of shares available under the 2022 Equity Incentive Plan includes 1,693,864 shares of Common
      Stock that were reserved, but not issued under the registrant&#8217;s 2005 Incentive Plan, 2010 Incentive Plan, 2015 Equity Incentive Plan, and 2020 Equity Incentive Plan as of July 29, 2022.</div>
    <div style="margin: 12pt 0px 0px; line-height: normal; text-align: justify; text-indent: 36pt;">The contents of the Company&#8217;s Registration Statement on Form&#160;S-8&#160;(No.&#160;333-197878)&#160;filed with the Commission on August&#160;5, 2014, the Registration Statement on
      Form&#160;S-8&#160;(No.&#160;333-218452)&#160;filed with the Commission on June 2, 2017, and the Registration Statement on Form&#160;S-8&#160;(No.&#160;333-232972)&#160;filed with the Commission on August 2, 2019, each relating to the ESPP, are incorporated by reference into this
      Registration Statement.</div>
    <div style="line-height: normal;"><br style="line-height: 12.55pt;">
    </div>
    <div style="line-height: normal; font-weight: bold; text-align: center;">PART I</div>
    <div style="margin: 12pt 0px 0px; line-height: normal; font-weight: bold; text-align: center;">INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS</div>
    <div style="line-height: 12.55pt;"><br style="line-height: 12.55pt;">
    </div>
    <div style="line-height: normal; text-align: justify; text-indent: 36pt;">The information specified in Item 1 and Item 2 of Part I of this Registration Statement on Form S-8 (the &#8220;Registration Statement&#8221;) is omitted from this filing in accordance with
      the provisions of Rule 428 under the Securities Act of 1933, as amended (the &#8220;Securities Act&#8221;), and the introductory note to Part I of the Registration Statement on Form S-8. The documents containing the information specified in Part I will be
      delivered to the participants in the 2022 Equity Incentive Plan and ESPP covered by this Registration Statement as required by Rule 428(b)(1).</div>
    <div style="line-height: normal; text-align: justify;">&#160;</div>
    <div id="DSPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
      <div id="DSPFPageNumberArea" style="text-align: center;"><font id="DSPFPageNumber" style="font-size: 8pt; font-weight: normal; font-style: normal;">1</font></div>
      <div id="DSPFPageBreak" style="page-break-after:always;">
        <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 1px; color: #AAAAAA; background-color: #AAAAAA; clear: both;"></div>
    </div>
    <div style="line-height: normal; font-weight: bold; text-align: center;">PART II</div>
    <div style="line-height: normal; font-weight: bold; text-align: center;">INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</div>
    <div style="margin: 12pt 0px 0px; line-height: normal;"><font style="font-weight: bold;">Item 3.</font>&#160; <font style="font-weight: bold;">Incorporation of Documents by Reference.</font></div>
    <div style="line-height: 12.55pt;"><br style="line-height: 12.55pt;">
    </div>
    <div style="line-height: normal; text-indent: 36pt;">The following documents, which are on file with the Commission, are incorporated herein by reference:</div>
    <div style="line-height: 12.55px;">
      <table cellspacing="0" cellpadding="0" id="z3b779de824a24555a38ad7a7e1b4b829" class="DSPFListTable" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

          <tr>
            <td style="width: 72pt; vertical-align: top; align: right;">
              <div style="margin: 0px 0px 0px 54pt; line-height: normal;">a.</div>
            </td>
            <td style="width: auto; vertical-align: top;">
              <div style="line-height: normal; text-align: justify;">The Company&#8217;s Annual Report on <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/935494/000093549422000007/nati-20211231.htm">Form 10-K</a> for the year ended December 31, 2021,
                filed with the Commission on February 22, 2022 (including information specifically incorporated by reference therein from the Company&#8217;s Definitive Proxy Statement filed with the Commission on March 28, 2022).</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <table cellspacing="0" cellpadding="0" id="z8ba427eac16647229318a8ee9832fdac" class="DSPFListTable" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

          <tr>
            <td style="width: 72pt; vertical-align: top; align: right;">
              <div style="margin: 0px 0px 0px 54pt; line-height: normal;">b.</div>
            </td>
            <td style="width: auto; vertical-align: top;">
              <div style="line-height: normal; text-align: justify;">The Company&#8217;s Quarterly Report on <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/935494/000093549422000011/nati-20220331.htm">Form 10-Q</a> for the three months ended March 31,
                2022, filed with the Commission on April 29, 2022.</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <table cellspacing="0" cellpadding="0" id="zb0ab715afb9242f5b3b82eec5808a40b" class="DSPFListTable" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

          <tr>
            <td style="width: 72pt; vertical-align: top; align: right;">
              <div style="margin: 0px 0px 0px 54pt; line-height: normal;">c.</div>
            </td>
            <td style="width: auto; vertical-align: top;">
              <div style="line-height: normal; text-align: justify;">The Company&#8217;s Quarterly Report on <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/935494/000093549422000022/nati-20220630.htm">Form 10-Q</a> for the three months ended June 30,
                2022, filed with the Commission on July 29, 2022.</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <table cellspacing="0" cellpadding="0" id="zb2346100107d46e98fdaa5cf04fb1998" class="DSPFListTable" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

          <tr>
            <td style="width: 72pt; vertical-align: top; align: right;">
              <div style="margin: 0px 0px 0px 54pt; line-height: normal;">d.</div>
            </td>
            <td style="width: auto; vertical-align: top;">
              <div style="line-height: normal;">The Company&#8217;s Current Reports on Form 8-K filed with the&#160;Commission&#160;on <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/935494/000093549422000003/form8-k.htm">January 27, 2022</a> (but only with
                regard to Item 8.01), <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/935494/000114036122016544/brhc10036769_8k.htm">April 28, 2022</a> (but only with regard to Item 8.01), <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/935494/000093549422000015/8-k.htm">May 12, 2022</a> and <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/935494/000093549422000019/form8-k.htm">July 28, 2022</a> (but only
                with regard to Item 8.01).</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <table cellspacing="0" cellpadding="0" id="z7953d337ff2248a3b79ac87bc353c9fc" class="DSPFListTable" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

          <tr>
            <td style="width: 72pt; vertical-align: top; align: right;">
              <div style="margin: 0px 0px 0px 54pt; line-height: normal;">e.</div>
            </td>
            <td style="width: auto; vertical-align: top;">
              <div style="line-height: normal; text-align: justify;">The Company&#8217;s description of authorized capital stock contained in its <a href="https://www.sec.gov/Archives/edgar/data/935494/000119312504070492/d8a12g.htm">registration statement</a>
                filed under Section 12 of the Securities Exchange Act of 1934, as amended (the &#8220;Exchange Act&#8221;), including any amendment or report filed for the purpose of updating the description.</div>
            </td>
          </tr>

      </table>
    </div>
    <div style="margin: 12pt 0px 0px; line-height: normal; text-align: justify; text-indent: 36pt;">All documents subsequently filed by the Company pursuant to Sections&#160;13(a), 13(c), 14 and 15(d) of the Exchange Act prior to the filing of a post-effective
      amendment that indicates that all securities offered have been sold or that deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference in this registration statement and to be part hereof from the date of filing
      of such documents. The Company is not, however, incorporating by reference any documents or portions thereof, whether specifically listed above or filed in the future, that are not deemed &#8220;filed&#8221; with the Commission, including any information
      furnished pursuant to Items 2.02 or 7.01 of Form 8-K or related exhibits furnished pursuant to Item 9.01 of Form 8-K.</div>
    <div style="margin: 12pt 0px 0px; line-height: normal; text-align: justify; text-indent: 36pt;">Any statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or superseded for
      purposes of this registration statement to the extent that a statement contained herein or in any other subsequently filed document that also is deemed to be incorporated by reference herein modifies or supersedes such statement. Any such statement
      so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this registration statement.</div>
    <div style="margin: 12pt 0px 0px; line-height: normal;"><font style="font-weight: bold;">Item 4.</font>&#160; <font style="font-weight: bold;">Description of Securities.</font></div>
    <div style="margin: 12pt 0px 0px; line-height: normal; text-indent: 36pt;">Not applicable.</div>
    <div style="margin: 12pt 0px 0px; line-height: normal;"><font style="font-weight: bold;">Item 5.</font>&#160; <font style="font-weight: bold;">Interests of Named Experts and Counsel.</font></div>
    <div style="margin: 12pt 0px 0px; line-height: normal; text-indent: 36pt;">Not applicable.</div>
    <div style="margin: 12pt 0px 0px; line-height: normal;"><font style="font-weight: bold;">Item 6.</font>&#160; <font style="font-weight: bold;">Indemnification of Directors and Officers.</font></div>
    <div style="margin: 12pt 0px 0px; line-height: normal; text-align: justify; text-indent: 36pt;">Section 145(a) of the Delaware General Corporation Law provides, in general, that a corporation shall have the power to indemnify any person who was or is a
      party or is threatened to be made a party to any threatened, pending or completed action, suit or proceeding, whether civil, criminal, administrative or investigative (other than an action by or in the right of the corporation), because the person is
      or was a director or officer of the corporation. Such indemnity may be against expenses (including attorneys&#8217; fees), judgments, fines and amounts paid in settlement actually and reasonably incurred by the person in connection with such action, suit
      or proceeding, if the person acted in good faith and in a manner the person reasonably believed to be in or not opposed to the best interests of the corporation and if, with respect to any criminal action or proceeding, the person did not have
      reasonable cause to believe the person&#8217;s conduct was unlawful.</div>
    <div id="DSPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
      <div id="DSPFPageNumberArea" style="text-align: center;"><font id="DSPFPageNumber" style="font-size: 8pt; font-weight: normal; font-style: normal;">2</font></div>
      <div id="DSPFPageBreak" style="page-break-after: always;">
        <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 1px; color: #aaaaaa; background-color: #aaaaaa;"></div>
    </div>
    <div style="margin: 12pt 0px 0px; line-height: normal; text-align: justify; text-indent: 36pt;">Section 145(b) of the Delaware General Corporation Law provides, in general, that a corporation shall have the power to indemnify any person who was or is a
      party or is threatened to be made a party to any threatened, pending or completed action or suit by or in the right of the corporation to procure a judgment in its favor because the person is or was a director or officer of the corporation, against
      any expenses (including attorneys&#8217; fees) actually and reasonably incurred by the person in connection with the defense or settlement of such action or suit if the person acted in good faith and in a manner the person reasonably believed to be in or
      not opposed to the best interests of the corporation.</div>
    <div style="margin: 12pt 0px 0px; line-height: normal; text-align: justify; text-indent: 36pt;">Section 145(g) of the Delaware General Corporation Law provides, in general, that a corporation shall have the power to purchase and maintain insurance on
      behalf of any person who is or was a director or officer of the corporation against any liability asserted against the person in any such capacity, or arising out of the person&#8217;s status as such, whether or not the corporation would have the power to
      indemnify the person against such liability under the provisions of the law.</div>
    <div style="margin: 12pt 0px 0px; line-height: normal; text-align: justify; text-indent: 36pt;">The Registrant&#8217;s certificate of incorporation, as amended, provides that, subject to certain limited exceptions, the Registrant may indemnify its directors
      and officers to the extent authorized or permitted by the Delaware General Corporation Law. The Registrant&#8217;s directors and officers are insured under policies of insurance maintained by the Registrant, subject to the limits of the policies, against
      certain losses arising from any claims made against them by reason of being or having been such directors or officers. In addition, the Registrant has entered into contracts with certain of its directors and officers providing for indemnification of
      such persons by the Registrant to the full extent authorized or permitted by law, subject to certain limited exceptions.</div>
    <div style="margin: 12pt 0px 0px; line-height: normal;"><font style="font-weight: bold;">Item 7.</font>&#160; <font style="font-weight: bold;">Exemption From Registration Claimed.</font></div>
    <div style="margin: 12pt 0px 0px; line-height: normal; text-indent: 36pt;">Not applicable.</div>
    <div id="DSPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
      <div id="DSPFPageNumberArea" style="text-align: center;"><font id="DSPFPageNumber" style="font-size: 8pt; font-weight: normal; font-style: normal;">3</font></div>
      <div id="DSPFPageBreak" style="page-break-after: always;">
        <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 1px; color: #aaaaaa; background-color: #aaaaaa;"></div>
    </div>
    <div style="line-height: 12.55pt; margin-top: 12pt; margin-bottom: 7pt;"><font style="font-weight: bold;">Item 8.</font>&#160; <font style="font-weight: bold;">Exhibits.</font></div>
    <table cellspacing="0" cellpadding="0" id="z8245f65fb6fe45e69317dbdf9801e02d" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

        <tr>
          <td style="width: 12.96%; vertical-align: bottom;">
            <div style="text-align: center; line-height: 11.4pt; font-weight: bold;">Exhibit</div>
            <div style="text-align: center; line-height: 11.4pt; font-weight: bold;">Number</div>
          </td>
          <td style="width: 87.04%; vertical-align: bottom;">
            <div style="line-height: 11.4pt; font-weight: bold;">Document</div>
          </td>
        </tr>
        <tr>
          <td style="width: 12.96%; vertical-align: top;">
            <div style="text-align: center; line-height: 12.55pt;">4.1</div>
          </td>
          <td style="width: 87.04%; vertical-align: bottom;">
            <div style="line-height: normal;"><a href="https://www.sec.gov/Archives/edgar/data/935494/000093549414000006/nati-20131231ex31d299188.htm">Certificate of Incorporation, as amended, of the Registrant, incorporated by reference to Exhibit 3.1 of
                the Registrant&#8217;s Annual Report on Form 10-K for the fiscal year ended December 31, 2021.</a></div>
          </td>
        </tr>
        <tr>
          <td style="width: 12.96%; vertical-align: top;">
            <div style="text-align: center; line-height: 12.55pt;">4.2</div>
          </td>
          <td style="width: 87.04%; vertical-align: bottom;">
            <div style="line-height: 12.55pt;"><a href="https://www.sec.gov/Archives/edgar/data/935494/000093549421000046/uwc-bylawsexhibit.htm">Amended and Restated Bylaws of the Registrant, incorporated by reference to Exhibit 3.2 of the Registrant&#8217;s
                Annual Report on Form 10-K for the fiscal year ended December 31, 2021.</a></div>
          </td>
        </tr>
        <tr>
          <td style="width: 12.96%; vertical-align: top;">
            <div style="text-align: center; line-height: 12.55pt;">4.3</div>
          </td>
          <td style="width: 87.04%; vertical-align: bottom;">
            <div style="line-height: 12.55pt;">Specimen of Common Stock certificate of the Registrant, incorporated by reference to the Registrant&#8217;s Registration Statement on Form S-1 (Reg. No. 33-88386) declared effective March 13, 1995.</div>
          </td>
        </tr>
        <tr>
          <td style="width: 12.96%; vertical-align: top;">
            <div style="text-align: center; line-height: 12.55pt;">4.4</div>
          </td>
          <td style="width: 87.04%; vertical-align: bottom;">
            <div style="line-height: 12.55pt;"><a href="https://www.sec.gov/Archives/edgar/data/935494/000093549422000015/ex-10_1.htm">2022 Equity Incentive Plan, incorporated by reference to Exhibit 10.1 of the Registrant&#8217;s Current Report on Form 8-K
                filed on May 12, 2022.</a></div>
          </td>
        </tr>
        <tr>
          <td style="width: 12.96%; vertical-align: top;">
            <div style="text-align: center; line-height: 12.55pt;">4.5</div>
          </td>
          <td style="width: 87.04%; vertical-align: bottom;">
            <div style="line-height: 12.55pt;"><a href="https://www.sec.gov/Archives/edgar/data/935494/000114036122011305/ny20002775x1_def14a.htm#tTOCA">1994 Employee Stock Purchase Plan, incorporated by reference to Exhibit A of the Registrant&#8217;s Proxy
                Statement dated March 28, 2022.</a></div>
          </td>
        </tr>
        <tr>
          <td style="width: 12.96%; vertical-align: top;">
            <div style="text-align: center; line-height: 12.55pt;">5.1</div>
          </td>
          <td style="width: 87.04%; vertical-align: bottom;">
            <div style="line-height: 12.55pt;"><a href="opinionofmofo.htm">Opinion of Morrison &amp; Foerster LLP.</a></div>
          </td>
        </tr>
        <tr>
          <td style="width: 12.96%; vertical-align: middle;">
            <div style="text-align: center; line-height: 12.55pt;">23.1</div>
          </td>
          <td style="width: 87.04%; vertical-align: bottom;">
            <div style="line-height: 12.55pt;"><a href="consentofernstyoungllp.htm">Consent of Ernst &amp; Young LLP, independent registered public accounting firm.</a></div>
          </td>
        </tr>
        <tr>
          <td style="width: 12.96%; vertical-align: middle;">
            <div style="text-align: center; line-height: 12.55pt;">23.2</div>
          </td>
          <td style="width: 87.04%; vertical-align: bottom;">
            <div style="line-height: 12.55pt;"><a href="opinionofmofo.htm">Consent of Morrison &amp; Foerster LLP (included in Exhibit&#160;5.1).</a></div>
          </td>
        </tr>
        <tr>
          <td style="width: 12.96%; vertical-align: middle;">
            <div style="text-align: center; line-height: 12.55pt;">24.1</div>
          </td>
          <td style="width: 87.04%; vertical-align: bottom;">
            <div style="line-height: 12.55pt;"><a href="#POWEROFATTORNEY">Power of Attorney (included on the signature page to this Registration Statement).</a></div>
          </td>
        </tr>
        <tr>
          <td style="width: 12.96%; vertical-align: middle;">
            <div style="text-align: center; line-height: 12.55pt;">107</div>
          </td>
          <td style="width: 87.04%; vertical-align: bottom;">
            <div style="line-height: 12.55pt;"><a href="filingfees.htm">Filing Fee Table.</a></div>
          </td>
        </tr>

    </table>
    <div style="margin: 12pt 0px 0px; line-height: normal;"><font style="font-weight: bold;">Item 9.</font>&#160; <font style="font-weight: bold;">Undertakings.</font></div>
    <div style="margin: 12pt 0px 0px; line-height: normal;">(a)<font class="HorizontalTab" style="width: 9pt; font-size: 1px; display: inline-block;"> </font>The undersigned registrant hereby undertakes:</div>
    <div style="margin: 12pt 0px 0px; line-height: normal; text-align: justify; text-indent: 36pt;">(1)<font class="HorizontalTab" style="width: 9pt; font-size: 1px; display: inline-block;"> </font>To file, during any period in which offers or sales are
      being made, a post-effective amendment to this registration statement:</div>
  </div>
  <div> <br>
  </div>
  <div>
    <div style="line-height: 14.4pt;">
      <div style="margin: 0px 0px 12pt 23pt; line-height: normal; text-align: justify; text-indent: 36pt;">(i) to include any prospectus required by Section 10(a)(3) of the Securities Act of 1933;</div>
      <div style="line-height: 0pt;"><br style="line-height: 0pt;">
      </div>
    </div>
    <div style="line-height: 14.4pt;">
      <div style="margin: 0px 0px 12pt 59pt; line-height: normal; text-align: justify;">(ii) to reflect in the prospectus any facts or events arising after the effective date of the registration statement (or the most recent post-effective amendment
        thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the registration statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total
        dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus filed with the Commission pursuant to Rule
        424(b) if, in the aggregate, the changes in volume and price represent no more than 20 percent change in the maximum aggregate offering price set forth in the &#8220;Calculation of Registration Fee&#8221; table in the effective registration statement; and</div>
    </div>
    <div style="margin: 0px 0px 12pt 59pt; line-height: normal; text-align: justify;">(iii) to include any material information with respect to the plan of distribution not previously disclosed in the registration statement or any material change to such
      information in the registration statement.<font style="font-style: italic;"></font></div>
    <div style="margin: 0px 0px 12pt 59pt; line-height: normal; text-align: justify;"><font style="font-style: italic;">Provided, however</font>, that paragraphs (a)(1)(i) and (a)(1)(ii) do not apply if the information required to be included in a
      post-effective amendment by those paragraphs is contained in reports filed with or furnished to the Commission by the registrant pursuant to Section 13 or Section 15(d) of the Securities Exchange Act of 1934 that are incorporated by reference in the
      registration statement.</div>
    <div style="line-height: 14.4pt;"> </div>
    <div style="margin: 12pt 0px 0px 9pt; line-height: normal; text-align: justify; text-indent: 36pt;">(2)<font class="HorizontalTab" style="width: 9pt; font-size: 1px; display: inline-block;"> </font>That, for the purpose of determining any liability
      under the Securities Act of 1933, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial
      bona fide offering thereof.</div>
    <div style="margin: 12pt 0px 0px 9pt; line-height: normal; text-align: justify; text-indent: 36pt;">(3)<font class="HorizontalTab" style="width: 9pt; font-size: 1px; display: inline-block;"> </font>To remove from registration by means of a
      post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.</div>
    <div style="margin: 12pt 0px 0px; line-height: normal; text-align: justify;">(b)<font class="HorizontalTab" style="width: 9pt; font-size: 1px; display: inline-block;"> </font>The undersigned registrant hereby undertakes that, for purposes of
      determining any liability under the Securities Act of 1933, each filing of the registrant&#8217;s annual report pursuant to Section&#160;13(a) or Section&#160;15(d) of the Securities Exchange Act of 1934 (and, where applicable, each filing of an employee benefit
      plan&#8217;s annual report pursuant to Section&#160;15(d) of the Securities Exchange Act of 1934) that is incorporated by reference in the registration statement shall be deemed to be a new registration statement relating to the securities offered therein, and
      the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.</div>
    <div style="margin: 12pt 0px 0px; line-height: normal; text-align: justify;">(h)<font class="HorizontalTab" style="width: 9pt; font-size: 1px; display: inline-block;"> </font>Insofar as indemnification for liabilities arising under the Securities Act
      of 1933 may be permitted to directors, officers and controlling persons of the registrant pursuant to the foregoing provisions, or otherwise, the registrant has been advised that in the opinion of the Securities and Exchange Commission such
      indemnification is against public policy as expressed in the Securities Act of 1933 and is, therefore, unenforceable.&#160; In the event that a claim for indemnification against such liabilities (other than the payment by the registrant of expenses
      incurred or paid by a director, officer or controlling person of the registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being
      registered, the registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against public policy as
      expressed in the Securities Act of 1933 and will be governed by the final adjudication of such issue.</div>
    <br>
    <div style="text-align: center; line-height: 18.05pt; font-weight: bold;">SIGNATURES</div>
    <div style="margin: 12pt 0px 0px; line-height: normal; text-align: justify; text-indent: 36pt;">Pursuant to the requirements of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all of the
      requirements for filing on Form&#160;S&#8209;8 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Austin, State of Texas, on August&#160;5, 2022.</div>
    <div><br>
    </div>
    <div>
      <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z188694b0633e4ad78d454682fe842ac8">

          <tr>
            <td style="width: 50%; vertical-align: bottom;">&#160;</td>
            <td colspan="2" style="vertical-align: bottom;">
              <div style="line-height: 11.4pt; font-weight: bold;">National Instruments Corporation</div>
            </td>
          </tr>
          <tr>
            <td style="width: 50%; vertical-align: bottom;">&#160;</td>
            <td colspan="2" style="vertical-align: bottom;">&#160;</td>
          </tr>
          <tr>
            <td style="width: 50%; vertical-align: bottom;">
              <div style="text-align: right; line-height: 11.4pt;">By:</div>
            </td>
            <td style="border-width: 1px 1px 2px; border-style: none none solid; border-color: -moz-use-text-color -moz-use-text-color rgb(0, 0, 0); vertical-align: bottom; width: 30%;">
              <div style="line-height: 12.55pt;">/s/ Eric H. Starkloff</div>
            </td>
            <td style="width: 20%; vertical-align: bottom;">&#160;</td>
          </tr>
          <tr>
            <td style="width: 50%; vertical-align: bottom;">&#160;</td>
            <td colspan="2" style="vertical-align: bottom;">
              <div style="line-height: 12.55pt;">Eric H. Starkloff</div>
              <div style="line-height: 12.55pt;">President and Chief Executive Officer</div>
            </td>
          </tr>

      </table>
    </div>
    <div id="DSPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
      <div id="DSPFPageNumberArea" style="text-align: center;"><font id="DSPFPageNumber" style="font-size: 8pt; font-weight: normal; font-style: normal;">4</font></div>
      <div id="DSPFPageBreak" style="page-break-after: always;">
        <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 1px; color: #aaaaaa; background-color: #aaaaaa;"></div>
    </div>
    <div style="text-align: center; line-height: 18.05pt; margin-top: 12pt; font-weight: bold;"><a name="POWEROFATTORNEY"><!--Anchor--></a>POWER OF ATTORNEY</div>
    <div style="margin: 12pt 0px 0px; line-height: normal; text-align: justify; text-indent: 36pt;">KNOW ALL PERSONS BY THESE PRESENT, that each person whose signature appears below constitutes and appoints Michael E. McGrath and Eric H. Starkloff, and
      each of them individually, as his or her true and lawful attorneys-in-fact and agents with full power of substitution and resubstitution, for the undersigned and in his or her name, place and stead, in any and all capacities to sign the registration
      statement filed herewith and any or all amendments to said registration statement with exhibits thereto and other documents in connection therewith, with the Commission, hereby ratifying and confirming all that each of said attorneys-in-fact, or his
      or her substitute or substitutes, may do or cause to be done by virtue hereof.</div>
    <div style="margin: 12pt 0px 19pt; line-height: normal; text-indent: 36pt;">Pursuant to the requirements of the Securities Act of 1933, this registration statement has been signed by the following persons in the capacities and on the dates indicated.</div>
    <table cellspacing="0" cellpadding="0" id="z7150ab460058472e869a5bf4e92e64a5" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

        <tr>
          <td style="width: 25.8%; vertical-align: bottom;">
            <div style="line-height: 11.4pt; font-weight: bold;"><u>Signature</u></div>
          </td>
          <td style="width: 55.44%; vertical-align: bottom;">
            <div style="line-height: 11.4pt; font-weight: bold;"><u>Title</u></div>
          </td>
          <td style="width: 18.76%; vertical-align: bottom;">
            <div style="line-height: 11.4pt; font-weight: bold;"><u>Date</u></div>
          </td>
        </tr>
        <tr>
          <td style="border-bottom: 0px none; border-left: 0px none; border-right: 0px none; border-top: 0px none; vertical-align: bottom; width: 25.8%;">&#160;</td>
          <td style="width: 55.44%; vertical-align: bottom;">&#160;</td>
          <td style="width: 18.76%; vertical-align: bottom;">&#160;</td>
        </tr>
        <tr>
          <td style="border-width: 0px 0px 2px; border-style: none none solid; border-color: -moz-use-text-color -moz-use-text-color rgb(0, 0, 0); vertical-align: bottom; width: 25.8%;">
            <div style="line-height: 11.4pt;">/s/ Michael E. McGrath</div>
          </td>
          <td style="width: 55.44%; vertical-align: bottom; padding-bottom: 2px;">
            <div style="line-height: 11.4pt;">Chairman of the Board</div>
          </td>
          <td style="width: 18.76%; vertical-align: bottom; padding-bottom: 2px;">
            <div style="line-height: 11.4pt;">August 5, 2022</div>
          </td>
        </tr>
        <tr>
          <td style="border-bottom: 0px; border-right: 0px; vertical-align: bottom; width: 25.8%;">
            <div style="line-height: 11.4pt;">Michael E. McGrath</div>
          </td>
          <td style="width: 55.44%; vertical-align: bottom;">&#160;</td>
          <td style="width: 18.76%; vertical-align: bottom;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 25.8%; vertical-align: bottom;">&#160;</td>
          <td style="width: 55.44%; vertical-align: bottom;">&#160;</td>
          <td style="width: 18.76%; vertical-align: bottom;">&#160;</td>
        </tr>
        <tr>
          <td style="border-width: 0px 0px 2px; border-style: none none solid; border-color: -moz-use-text-color -moz-use-text-color rgb(0, 0, 0); vertical-align: bottom; width: 25.8%;">
            <div style="line-height: 11.4pt;">/s/ Eric H. Starkloff</div>
          </td>
          <td style="width: 55.44%; vertical-align: top;" rowspan="2">
            <div style="line-height: 11.4pt;">Director, President and Chief Executive Officer (Principal Executive Officer)</div>
          </td>
          <td style="width: 18.76%; vertical-align: bottom; padding-bottom: 2px;">
            <div style="line-height: 11.4pt;">August 5, 2022</div>
          </td>
        </tr>
        <tr>
          <td style="width: 25.8%; vertical-align: bottom;">
            <div style="line-height: 11.4pt;">Eric H. Starkloff</div>
          </td>
          <td style="width: 18.76%; vertical-align: bottom;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 25.8%; vertical-align: bottom;">&#160;</td>
          <td style="width: 55.44%; vertical-align: bottom;">&#160;</td>
          <td style="width: 18.76%; vertical-align: bottom;">&#160;</td>
        </tr>
        <tr>
          <td style="border-width: 1px 1px 2px; border-style: none none solid; border-color: -moz-use-text-color -moz-use-text-color rgb(0, 0, 0); vertical-align: bottom; width: 25.8%;">
            <div style="line-height: 11.4pt;">/s/ Karen M. Rapp</div>
          </td>
          <td style="width: 55.44%; vertical-align: top;" rowspan="2">
            <div style="line-height: 11.4pt;">Executive Vice President and Chief Financial Officer (Principal Financial Officer and Principal Accounting Officer)</div>
          </td>
          <td style="width: 18.76%; vertical-align: bottom; padding-bottom: 2px;">
            <div style="line-height: 11.4pt;">August 5, 2022</div>
          </td>
        </tr>
        <tr>
          <td style="width: 25.8%; vertical-align: bottom;">
            <div style="line-height: 11.4pt;">Karen M. Rapp</div>
          </td>
          <td style="width: 18.76%; vertical-align: bottom;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 25.8%; vertical-align: bottom;">&#160;</td>
          <td style="width: 55.44%; vertical-align: bottom;">&#160;</td>
          <td style="width: 18.76%; vertical-align: bottom;">&#160;</td>
        </tr>
        <tr>
          <td style="border-bottom: 2px solid #000000; border-left: 0px none; border-right: 0px none; border-top: 0px none; vertical-align: bottom; width: 25.8%;">
            <div style="line-height: 11.4pt;">/s/ James E. Cashman, III</div>
          </td>
          <td style="width: 55.44%; vertical-align: bottom; padding-bottom: 2px;">
            <div style="line-height: 11.4pt;">Director</div>
          </td>
          <td style="width: 18.76%; vertical-align: bottom; padding-bottom: 2px;">
            <div style="line-height: 11.4pt;">August 5, 2022</div>
          </td>
        </tr>
        <tr>
          <td style="width: 25.8%; vertical-align: bottom;">
            <div style="line-height: 11.4pt;">James E. Cashman, III</div>
          </td>
          <td style="width: 55.44%; vertical-align: bottom;">&#160;</td>
          <td style="width: 18.76%; vertical-align: bottom;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 25.8%; vertical-align: bottom;">&#160;</td>
          <td style="width: 55.44%; vertical-align: bottom;">&#160;</td>
          <td style="width: 18.76%; vertical-align: bottom;">&#160;</td>
        </tr>
        <tr>
          <td style="border-bottom: 2px solid #000000; border-left: 0px none; border-right: 0px none; border-top: 0px none; vertical-align: bottom; width: 25.8%;">
            <div style="line-height: 11.4pt;">/s/ Alexander M. Davern</div>
          </td>
          <td style="width: 55.44%; vertical-align: bottom; padding-bottom: 2px;">
            <div style="line-height: 11.4pt;">Director</div>
          </td>
          <td style="width: 18.76%; vertical-align: bottom; padding-bottom: 2px;">
            <div style="line-height: 11.4pt;">August 5, 2022</div>
          </td>
        </tr>
        <tr>
          <td style="width: 25.8%; vertical-align: bottom;">
            <div style="line-height: 11.4pt;">Alexander M. Davern</div>
          </td>
          <td style="width: 55.44%; vertical-align: bottom;">&#160;</td>
          <td style="width: 18.76%; vertical-align: bottom;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 25.8%; vertical-align: bottom;">&#160;</td>
          <td style="width: 55.44%; vertical-align: bottom;">&#160;</td>
          <td style="width: 18.76%; vertical-align: bottom;">&#160;</td>
        </tr>
        <tr>
          <td style="border-width: 1px 1px 2px; border-style: none none solid; border-color: -moz-use-text-color -moz-use-text-color rgb(0, 0, 0); vertical-align: bottom; width: 25.8%;">
            <div style="line-height: 11.4pt;">/s/ Gayla J. Delly</div>
          </td>
          <td style="width: 55.44%; vertical-align: bottom; padding-bottom: 2px;">
            <div style="line-height: 11.4pt;">Director</div>
          </td>
          <td style="width: 18.76%; vertical-align: bottom; padding-bottom: 2px;">
            <div style="line-height: 11.4pt;">August 5, 2022</div>
          </td>
        </tr>
        <tr>
          <td style="width: 25.8%; vertical-align: bottom;">
            <div style="line-height: 11.4pt;">Gayla J. Delly</div>
          </td>
          <td style="width: 55.44%; vertical-align: bottom;">&#160;</td>
          <td style="width: 18.76%; vertical-align: bottom;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 25.8%; vertical-align: bottom;">&#160;</td>
          <td style="width: 55.44%; vertical-align: bottom;">&#160;</td>
          <td style="width: 18.76%; vertical-align: bottom;">&#160;</td>
        </tr>
        <tr>
          <td style="border-width: 0px 0px 2px; border-style: none none solid; border-color: -moz-use-text-color -moz-use-text-color rgb(0, 0, 0); vertical-align: bottom; width: 25.8%;">
            <div style="line-height: 11.4pt;">/s/ Gerhard P. Fettweis</div>
          </td>
          <td style="width: 55.44%; vertical-align: bottom; padding-bottom: 2px;">
            <div style="line-height: 11.4pt;">Director</div>
          </td>
          <td style="width: 18.76%; vertical-align: bottom; padding-bottom: 2px;">
            <div style="line-height: 11.4pt;">August 5, 2022</div>
          </td>
        </tr>
        <tr>
          <td style="width: 25.8%; vertical-align: bottom; border-top: 0px solid rgb(0, 0, 0);">
            <div style="line-height: 11.4pt;">Gerhard P. Fettweis</div>
          </td>
          <td style="width: 55.44%; vertical-align: bottom;">&#160;</td>
          <td style="width: 18.76%; vertical-align: bottom;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 25.8%; vertical-align: bottom;">&#160;</td>
          <td style="width: 55.44%; vertical-align: bottom;">&#160;</td>
          <td style="width: 18.76%; vertical-align: bottom;">&#160;</td>
        </tr>
        <tr>
          <td style="border-width: 1px 1px 2px; border-style: none none solid; border-color: -moz-use-text-color -moz-use-text-color rgb(0, 0, 0); vertical-align: bottom; width: 25.8%;">
            <div style="line-height: 11.4pt;">/s/ Liam K. Griffin</div>
          </td>
          <td style="width: 55.44%; vertical-align: bottom; padding-bottom: 2px;">
            <div style="line-height: 11.4pt;">Director</div>
          </td>
          <td style="width: 18.76%; vertical-align: bottom; padding-bottom: 2px;">
            <div style="line-height: 11.4pt;">August 5, 2022</div>
          </td>
        </tr>
        <tr>
          <td style="width: 25.8%; vertical-align: bottom;">
            <div style="line-height: 11.4pt;">Liam K. Griffin</div>
          </td>
          <td style="width: 55.44%; vertical-align: bottom;">&#160;</td>
          <td style="width: 18.76%; vertical-align: bottom;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 25.8%; vertical-align: bottom;">&#160;</td>
          <td style="width: 55.44%; vertical-align: bottom;">&#160;</td>
          <td style="width: 18.76%; vertical-align: bottom;">&#160;</td>
        </tr>
        <tr>
          <td style="border-width: 1px 1px 2px; border-style: none none solid; border-color: -moz-use-text-color -moz-use-text-color rgb(0, 0, 0); vertical-align: bottom; width: 25.8%;">
            <div style="line-height: 11.4pt;">/s/ Duy-Loan T. Le</div>
          </td>
          <td style="width: 55.44%; vertical-align: bottom; padding-bottom: 2px;">
            <div style="line-height: 11.4pt;">Director</div>
          </td>
          <td style="width: 18.76%; vertical-align: bottom; padding-bottom: 2px;">
            <div style="line-height: 11.4pt;">August 5, 2022</div>
          </td>
        </tr>
        <tr>
          <td style="width: 25.8%; vertical-align: bottom;">
            <div style="line-height: 11.4pt;">Duy-Loan T. Le</div>
          </td>
          <td style="width: 55.44%; vertical-align: bottom;">&#160;</td>
          <td style="width: 18.76%; vertical-align: bottom;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 25.8%; vertical-align: bottom;">&#160;</td>
          <td style="width: 55.44%; vertical-align: bottom;">&#160;</td>
          <td style="width: 18.76%; vertical-align: bottom;">&#160;</td>
        </tr>

    </table>
    <div style="line-height: 2pt;"><br style="line-height: 2pt;">
    </div>
    <div style="line-height: 16.4pt;"><br style="line-height: 16.4pt;">
    </div>
  </div>
  <div id="DSPFPageNumberArea" style="text-align: center;"><font id="DSPFPageNumber" style="font-size: 8pt; font-weight: normal; font-style: normal;">5</font></div>
</body>
</html>
[{"type": "S-8", "sequence": "1", "filename": "s-8.htm", "description": "S-8", "secsgml_size_bytes": 58294}]
{"company-data": {"conformed-name": "NATIONAL INSTRUMENTS CORP", "cik": "0000935494", "assigned-sic": "7372", "irs-number": "741871327", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-266560", "film-number": "221138847"}, "business-address": {"street1": "11500 NORTH MOPAC EXPRESSWAY", "city": "AUSTIN", "state": "TX", "zip": "78759", "phone": "5123389119"}, "mail-address": {"street1": "11500 NORTH MOPAC EXPRESSWAY", "city": "AUSTIN", "state": "TX", "zip": "78759"}, "former-company": {"former-conformed-name": "NATIONAL INSTRUMENTS CORP /DE/", "date-changed": "19950113"}}
As filed with the Securities and Exchange Commission on August 5, 2022
Registration No. 333-_____
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S
‑
8
REGISTRATION STATEMENT
Under
The Securities Act of 1933
NATIONAL INSTRUMENTS CORPORATION
(Exact name of registrant as specified in its charter)
Delaware
74-1871327
(State or other jurisdiction of
incorporation or organization)
(I.R.S. Employer
Identification Number)
11500 North MoPac Expressway
Austin, Texas 78759
(Address, including zip code, of registrant's principal executive offices)
National Instruments Corporation 2022 Equity Incentive Plan
National Instruments Corporation 1994 Employee Stock Purchase Plan
(Full title of the Plan)
R. Eddie Dixon, Jr.
Senior Vice President, Chief Legal Officer and Secretary
National Instruments Corporation
11500 North Mopac Expressway
Austin, Texas 78759
(512) 683-0100
(Name, address, and telephone number, including area code, of agent for service)
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth
        company. See the definitions of "large accelerated filer," "accelerated filer," "smaller reporting company" and "emerging growth company" in Rule 12b-2 of the Exchange Act. (Check one):
Large accelerated filer
☒
Accelerated filer
☐
Non-accelerated filer
☐
Smaller reporting company
☐
Emerging growth company
☐
If an emerging growth company, indicate by checkmark if the registrant has elected not to use the extended transition period for complying with any new or revised financial
        accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act.
☐
EXPLANATORY NOTE
National Instruments Corporation (the "Registrant" or "Company") is filing this registration statement to register the issuance of 6,123,921 shares of its
      common stock, $0.01 par value per share (the "Common Stock"), reserved under the National Instruments Corporation 2022 Equity Incentive Plan (the "2022 Equity Incentive Plan") and an additional 3,000,000 shares of Common Stock under the National
      Instruments Corporation 1994 Employee Stock Purchase Plan (the "ESPP"). The 2022 Equity Incentive Plan and additional 3,000,000 shares of Common Stock under the ESPP were described in the Company's definitive proxy statement, filed with the United
      States Securities and Exchange Commission (the "Commission") on March 28, 2022, and were approved by the Company's shareholders on May 10, 2022. The number of shares available under the 2022 Equity Incentive Plan includes 1,693,864 shares of Common
      Stock that were reserved, but not issued under the registrant's 2005 Incentive Plan, 2010 Incentive Plan, 2015 Equity Incentive Plan, and 2020 Equity Incentive Plan as of July 29, 2022.
The contents of the Company's Registration Statement on Form S-8 (No. 333-197878) filed with the Commission on August 5, 2014, the Registration Statement on
      Form S-8 (No. 333-218452) filed with the Commission on June 2, 2017, and the Registration Statement on Form S-8 (No. 333-232972) filed with the Commission on August 2, 2019, each relating to the ESPP, are incorporated by reference into this
      Registration Statement.
PART I
INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS
The information specified in Item 1 and Item 2 of Part I of this Registration Statement on Form S-8 (the "Registration Statement") is omitted from this filing in accordance with
      the provisions of Rule 428 under the Securities Act of 1933, as amended (the "Securities Act"), and the introductory note to Part I of the Registration Statement on Form S-8. The documents containing the information specified in Part I will be
      delivered to the participants in the 2022 Equity Incentive Plan and ESPP covered by this Registration Statement as required by Rule 428(b)(1).
1
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 3.
Incorporation of Documents by Reference.
The following documents, which are on file with the Commission, are incorporated herein by reference:
a.
The Company's Annual Report on
Form 10-K
for the year ended December 31, 2021,
                filed with the Commission on February 22, 2022 (including information specifically incorporated by reference therein from the Company's Definitive Proxy Statement filed with the Commission on March 28, 2022).
b.
The Company's Quarterly Report on
Form 10-Q
for the three months ended March 31,
                2022, filed with the Commission on April 29, 2022.
c.
The Company's Quarterly Report on
Form 10-Q
for the three months ended June 30,
                2022, filed with the Commission on July 29, 2022.
d.
The Company's Current Reports on Form 8-K filed with the Commission on
January 27, 2022
(but only with
                regard to Item 8.01),
April 28, 2022
(but only with regard to Item 8.01),
May 12, 2022
and
July 28, 2022
(but only
                with regard to Item 8.01).
e.
The Company's description of authorized capital stock contained in its
registration statement
filed under Section 12 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), including any amendment or report filed for the purpose of updating the description.
All documents subsequently filed by the Company pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act prior to the filing of a post-effective
      amendment that indicates that all securities offered have been sold or that deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference in this registration statement and to be part hereof from the date of filing
      of such documents. The Company is not, however, incorporating by reference any documents or portions thereof, whether specifically listed above or filed in the future, that are not deemed "filed" with the Commission, including any information
      furnished pursuant to Items 2.02 or 7.01 of Form 8-K or related exhibits furnished pursuant to Item 9.01 of Form 8-K.
Any statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or superseded for
      purposes of this registration statement to the extent that a statement contained herein or in any other subsequently filed document that also is deemed to be incorporated by reference herein modifies or supersedes such statement. Any such statement
      so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this registration statement.
Item 4.
Description of Securities.
Not applicable.
Item 5.
Interests of Named Experts and Counsel.
Not applicable.
Item 6.
Indemnification of Directors and Officers.
Section 145(a) of the Delaware General Corporation Law provides, in general, that a corporation shall have the power to indemnify any person who was or is a
      party or is threatened to be made a party to any threatened, pending or completed action, suit or proceeding, whether civil, criminal, administrative or investigative (other than an action by or in the right of the corporation), because the person is
      or was a director or officer of the corporation. Such indemnity may be against expenses (including attorneys' fees), judgments, fines and amounts paid in settlement actually and reasonably incurred by the person in connection with such action, suit
      or proceeding, if the person acted in good faith and in a manner the person reasonably believed to be in or not opposed to the best interests of the corporation and if, with respect to any criminal action or proceeding, the person did not have
      reasonable cause to believe the person's conduct was unlawful.
2
Section 145(b) of the Delaware General Corporation Law provides, in general, that a corporation shall have the power to indemnify any person who was or is a
      party or is threatened to be made a party to any threatened, pending or completed action or suit by or in the right of the corporation to procure a judgment in its favor because the person is or was a director or officer of the corporation, against
      any expenses (including attorneys' fees) actually and reasonably incurred by the person in connection with the defense or settlement of such action or suit if the person acted in good faith and in a manner the person reasonably believed to be in or
      not opposed to the best interests of the corporation.
Section 145(g) of the Delaware General Corporation Law provides, in general, that a corporation shall have the power to purchase and maintain insurance on
      behalf of any person who is or was a director or officer of the corporation against any liability asserted against the person in any such capacity, or arising out of the person's status as such, whether or not the corporation would have the power to
      indemnify the person against such liability under the provisions of the law.
The Registrant's certificate of incorporation, as amended, provides that, subject to certain limited exceptions, the Registrant may indemnify its directors
      and officers to the extent authorized or permitted by the Delaware General Corporation Law. The Registrant's directors and officers are insured under policies of insurance maintained by the Registrant, subject to the limits of the policies, against
      certain losses arising from any claims made against them by reason of being or having been such directors or officers. In addition, the Registrant has entered into contracts with certain of its directors and officers providing for indemnification of
      such persons by the Registrant to the full extent authorized or permitted by law, subject to certain limited exceptions.
Item 7.
Exemption From Registration Claimed.
Not applicable.
3
Item 8.
Exhibits.
Exhibit
Number
Document
4.1
Certificate of Incorporation, as amended, of the Registrant, incorporated by reference to Exhibit 3.1 of
                the Registrant's Annual Report on Form 10-K for the fiscal year ended December 31, 2021.
4.2
Amended and Restated Bylaws of the Registrant, incorporated by reference to Exhibit 3.2 of the Registrant's
                Annual Report on Form 10-K for the fiscal year ended December 31, 2021.
4.3
Specimen of Common Stock certificate of the Registrant, incorporated by reference to the Registrant's Registration Statement on Form S-1 (Reg. No. 33-88386) declared effective March 13, 1995.
4.4
2022 Equity Incentive Plan, incorporated by reference to Exhibit 10.1 of the Registrant's Current Report on Form 8-K
                filed on May 12, 2022.
4.5
1994 Employee Stock Purchase Plan, incorporated by reference to Exhibit A of the Registrant's Proxy
                Statement dated March 28, 2022.
5.1
Opinion of Morrison & Foerster LLP.
23.1
Consent of Ernst & Young LLP, independent registered public accounting firm.
23.2
Consent of Morrison & Foerster LLP (included in Exhibit 5.1).
24.1
Power of Attorney (included on the signature page to this Registration Statement).
107
Filing Fee Table.
Item 9.
Undertakings.
(a)
The undersigned registrant hereby undertakes:
(1)
To file, during any period in which offers or sales are
      being made, a post-effective amendment to this registration statement:
(i) to include any prospectus required by Section 10(a)(3) of the Securities Act of 1933;
(ii) to reflect in the prospectus any facts or events arising after the effective date of the registration statement (or the most recent post-effective amendment
        thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the registration statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total
        dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus filed with the Commission pursuant to Rule
        424(b) if, in the aggregate, the changes in volume and price represent no more than 20 percent change in the maximum aggregate offering price set forth in the "Calculation of Registration Fee" table in the effective registration statement; and
(iii) to include any material information with respect to the plan of distribution not previously disclosed in the registration statement or any material change to such
      information in the registration statement.
Provided, however
, that paragraphs (a)(1)(i) and (a)(1)(ii) do not apply if the information required to be included in a
      post-effective amendment by those paragraphs is contained in reports filed with or furnished to the Commission by the registrant pursuant to Section 13 or Section 15(d) of the Securities Exchange Act of 1934 that are incorporated by reference in the
      registration statement.
(2)
That, for the purpose of determining any liability
      under the Securities Act of 1933, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial
      bona fide offering thereof.
(3)
To remove from registration by means of a
      post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.
(b)
The undersigned registrant hereby undertakes that, for purposes of
      determining any liability under the Securities Act of 1933, each filing of the registrant's annual report pursuant to Section 13(a) or Section 15(d) of the Securities Exchange Act of 1934 (and, where applicable, each filing of an employee benefit
      plan's annual report pursuant to Section 15(d) of the Securities Exchange Act of 1934) that is incorporated by reference in the registration statement shall be deemed to be a new registration statement relating to the securities offered therein, and
      the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.
(h)
Insofar as indemnification for liabilities arising under the Securities Act
      of 1933 may be permitted to directors, officers and controlling persons of the registrant pursuant to the foregoing provisions, or otherwise, the registrant has been advised that in the opinion of the Securities and Exchange Commission such
      indemnification is against public policy as expressed in the Securities Act of 1933 and is, therefore, unenforceable.  In the event that a claim for indemnification against such liabilities (other than the payment by the registrant of expenses
      incurred or paid by a director, officer or controlling person of the registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being
      registered, the registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against public policy as
      expressed in the Securities Act of 1933 and will be governed by the final adjudication of such issue.
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all of the
      requirements for filing on Form S‑8 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Austin, State of Texas, on August 5, 2022.
National Instruments Corporation
By:
/s/ Eric H. Starkloff
Eric H. Starkloff
President and Chief Executive Officer
4
POWER OF ATTORNEY
KNOW ALL PERSONS BY THESE PRESENT, that each person whose signature appears below constitutes and appoints Michael E. McGrath and Eric H. Starkloff, and
      each of them individually, as his or her true and lawful attorneys-in-fact and agents with full power of substitution and resubstitution, for the undersigned and in his or her name, place and stead, in any and all capacities to sign the registration
      statement filed herewith and any or all amendments to said registration statement with exhibits thereto and other documents in connection therewith, with the Commission, hereby ratifying and confirming all that each of said attorneys-in-fact, or his
      or her substitute or substitutes, may do or cause to be done by virtue hereof.
Pursuant to the requirements of the Securities Act of 1933, this registration statement has been signed by the following persons in the capacities and on the dates indicated.
Signature
Title
Date
/s/ Michael E. McGrath
Chairman of the Board
August 5, 2022
Michael E. McGrath
/s/ Eric H. Starkloff
Director, President and Chief Executive Officer (Principal Executive Officer)
August 5, 2022
Eric H. Starkloff
/s/ Karen M. Rapp
Executive Vice President and Chief Financial Officer (Principal Financial Officer and Principal Accounting Officer)
August 5, 2022
Karen M. Rapp
/s/ James E. Cashman, III
Director
August 5, 2022
James E. Cashman, III
/s/ Alexander M. Davern
Director
August 5, 2022
Alexander M. Davern
/s/ Gayla J. Delly
Director
August 5, 2022
Gayla J. Delly
/s/ Gerhard P. Fettweis
Director
August 5, 2022
Gerhard P. Fettweis
/s/ Liam K. Griffin
Director
August 5, 2022
Liam K. Griffin
/s/ Duy-Loan T. Le
Director
August 5, 2022
Duy-Loan T. Le
5