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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>As filed with the Securities and Exchange
Commission on April 14, 2017</B></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right; border-bottom: Black 4.5pt double"><B>Registration
No. 333-______</B></P>

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<P STYLE="font: 14pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">UNITED STATES&nbsp;</P>

<P STYLE="font: 14pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">SECURITIES AND EXCHANGE COMMISSION&nbsp;</P>

<P STYLE="font: 13pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Washington, D.C. 20549</P>

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<P STYLE="font: 13pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;FORM S-8&nbsp;</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">REGISTRATION STATEMENT<BR>
UNDER THE SECURITIES ACT OF 1933&nbsp;</P>



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<P STYLE="font: 14pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Auris Medical Holding AG</P>

<P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Exact Name of Registrant as Specified in
Its Charter)</P>

<P STYLE="font: 8pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

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<TR STYLE="vertical-align: top">
    <TD STYLE="width: 34%; text-align: center"><B>Switzerland</B></TD>
    <TD STYLE="width: 33%; text-align: center">&nbsp;</TD>
    <TD STYLE="width: 33%; text-align: center"><B>Not Applicable</B></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: center"><FONT STYLE="font-size: 8pt">(State or Other Jurisdiction of </FONT><BR>
<FONT STYLE="font-size: 8pt">Incorporation or Organization)</FONT></TD>
    <TD STYLE="text-align: center">&nbsp;</TD>
    <TD STYLE="text-align: center"><FONT STYLE="font-size: 8pt">(I.R.S. Employer</FONT><BR>
<FONT STYLE="font-size: 8pt">Identification Number)</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD STYLE="text-align: center"><B>Bahnhofstrasse 21</B><BR>
<B>6300 Zug</B><BR>
<B>Switzerland</B></TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD COLSPAN="3" STYLE="text-align: center"><P STYLE="margin-top: 0; margin-bottom: 0"><FONT STYLE="font-size: 8pt">(Address,
Including Zip Code of Principal Executive Offices)</FONT></P></TD></TR>
</TABLE>


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<TR STYLE="vertical-align: top">
    <TD STYLE="width: 100%; text-align: center"><B>Auris Medical Holding AG Equity Incentive Plan, as amended</B></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: center"><FONT STYLE="font-size: 8pt">(Full title of Plans)</FONT></TD></TR>
</TABLE>

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<P STYLE="margin-top: 0; margin-bottom: 0">&nbsp;&nbsp;</P>

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<TR STYLE="vertical-align: top">
    <TD STYLE="width: 100%; text-align: center"><B>National Corporate Research, Ltd.</B><BR>
<B>10 East 40<SUP>th</SUP> Street</B><BR>
<B>New York, New York 10016</B><BR>
<B>(212) 947-7200</B></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: center"><FONT STYLE="font-size: 8pt">(Name, address and telephone number, including area code, of agent for service)</FONT></TD></TR>
</TABLE>


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<TR STYLE="vertical-align: top">
    <TD STYLE="width: 34%">&nbsp;</TD>
    <TD STYLE="width: 33%; text-align: center"><B><I>Copies to:</I></B></TD>
    <TD STYLE="width: 33%">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: center">&nbsp;</TD>
    <TD>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Sophia Hudson&nbsp;</B></P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Davis Polk &amp; Wardwell LLP&nbsp;</B></P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>450 Lexington Avenue&nbsp;</B></P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>New York, New York 10017&nbsp;</B></P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(212) 450-4000&nbsp;</B></P></TD>
    <TD STYLE="text-align: center">&nbsp;</TD></TR>
</TABLE>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">Indicate by check mark whether the registrant
is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions
of &ldquo;large accelerated filer,&rdquo; &ldquo;accelerated filer&rdquo; and &ldquo;smaller reporting company&rdquo; in Rule 12b-2
of the Exchange Act.</P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">Large accelerated filer <FONT STYLE="font-family: MS Mincho">&#9744;</FONT>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&#9;Accelerated
filer <FONT STYLE="font-family: MS Mincho">&#9744;</FONT></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">Non-accelerated filer <FONT STYLE="font-family: MS Gothic, Helvetica, Sans-Serif">&#9746;</FONT>
(Do not check if a smaller reporting company)&#9;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Smaller reporting company <FONT STYLE="font-family: MS Mincho">&#9744;</FONT></P>

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<P STYLE="margin-top: 0; margin-bottom: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
<TR STYLE="vertical-align: bottom">
    <TD COLSPAN="5" STYLE="border-bottom: Black 1.5pt double; text-align: center"><FONT STYLE="font-size: 10pt"><B>CALCULATION OF REGISTRATION FEE</B></FONT></TD></TR>
<TR STYLE="vertical-align: bottom">
    <TD STYLE="width: 47%; border-bottom: Black 1pt solid; border-right: Black 1pt solid; text-align: center; font-weight: bold">Title Of Securities To Be Registered</TD>
    <TD STYLE="width: 11%; border-bottom: Black 1pt solid; border-right: Black 1pt solid; text-align: center; font-weight: bold">Amount To Be Registered(1)</TD>
    <TD STYLE="width: 15%; border-bottom: Black 1pt solid; border-right: Black 1pt solid; text-align: center; font-weight: bold">Proposed Maximum Offering Price Per Share(2)</TD>
    <TD STYLE="width: 13%; border-bottom: Black 1pt solid; border-right: Black 1pt solid; text-align: center; font-weight: bold">Proposed Maximum Aggregate Offering Price(2)</TD>
    <TD STYLE="width: 14%; border-bottom: Black 1pt solid; text-align: center; font-weight: bold">Amount Of<BR>
Registration Fee</TD></TR>
<TR STYLE="vertical-align: bottom">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">Common Shares, nominal value CHF 0.40 per share&nbsp;&#9;</TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center">5,141,000</TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center">$0.72</TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center">$3,701,520</TD>
    <TD STYLE="border-bottom: Black 1pt solid; text-align: center">$429.01</TD></TR>
</TABLE>
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<TD STYLE="width: 0"></TD><TD STYLE="width: 0.25in">(1)</TD><TD>This Registration Statement on Form S-8 (this &ldquo;Registration Statement&rdquo;) covers (i) common shares, nominal value
CHF 0.40 per share (&ldquo;Common Shares&rdquo;), of Auris Medical Holding AG (the &ldquo;Registrant&rdquo;), issuable pursuant
to the Auris Medical Holding AG Equity Incentive Plan, as amended (the &ldquo;EIP&rdquo;); and (ii) pursuant to Rule 416(a) under
the Securities Act of 1933, as amended (the &ldquo;Securities Act&rdquo;), any additional Common Shares that become issuable under
the EIP by reason of any share dividend, share split or other similar transaction.</TD></TR></TABLE>

<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font: 8pt Times New Roman, Times, Serif">&nbsp;</P>

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<TD STYLE="width: 0"></TD><TD STYLE="width: 0.25in">(2)</TD><TD>Estimated pursuant to Rule 457(h) and Rule 457(c) under the Securities Act, solely for the purpose of computing the registration
fee for Common Shares to be issued pursuant to the EIP, based on the average of the high and low prices reported for a Common Share
on the NASDAQ Global Select Market on April 7, 2017.</TD></TR></TABLE>

<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font: 8pt Times New Roman, Times, Serif">&nbsp;</P>


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<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">EXPLANATORY NOTE</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">This Registration Statement has been prepared
and filed pursuant to and in accordance with the requirements of General Instruction E to Form S-8 for the purpose of registering
an additional 5,141,000 Common Shares that are issuable at any time or from time to time under the EIP. Pursuant to General Instruction
E, the contents of the Registration Statement on Form S-8 filed for the EIP with the U.S. Securities and Exchange Commission (the
&ldquo;Commission&rdquo;) on December 8, 2014 (Registration File No. 333-200805), including the documents incorporated by reference
therein, are incorporated by reference into this Registration Statement, except as supplemented by the information set forth below.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">PART I</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">INFORMATION REQUIRED IN THE SECTION
10(a) PROSPECTUS</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">The documents containing the information
specified in Item 1 and Item 2 of Part I of Form S-8 will be delivered to participants as specified by Rule 428(b)(1) under the
Securities Act. In accordance with the rules and regulations of the Commission and the instructions to Form S-8, such documents
are not being filed with the Commission either as part of this Registration Statement or as prospectuses or prospectus supplements
pursuant to Rule 424 under the Securities Act.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">PART II</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">INFORMATION REQUIRED IN THE REGISTRATION
STATEMENT</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0">Item 3. Incorporation of Documents by Reference.</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">The following documents are incorporated
herein by reference:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">(a)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The
Registrant&rsquo;s Annual Report on Form 20-F for the fiscal year ended December 31, 2016, filed with the Commission on March 14,
2017 (Registration File No. 001-36582).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">(b)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;All
reports filed pursuant to Section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended (the &ldquo;Exchange Act&rdquo;),
since December 31, 2016.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">(c)
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The description of the Registrant&rsquo;s Common Shares which is contained in the
Registrant&rsquo;s Exchange Act Registration Statement on Form 8-A (Registration File No. 001-36582), dated July 29, 2014 and
amended on June 1, 2016, including any amendments or supplements thereto or report filed for the purpose of updating such
description.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">In addition, all documents subsequently
filed by the Registrant with the Commission pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act, prior to the filing
of a post-effective amendment to this Registration Statement which indicates that all securities offered have been sold or which
deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference in this Registration Statement
and to be a part hereof from the date of the filing of such documents.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">Any statement contained in a document incorporated
or deemed to be incorporated by reference herein shall be deemed to be modified or superseded for purposes of this Registration
Statement to the extent that a statement contained herein (or in any other subsequently filed document which also is incorporated
or deemed to be incorporated by reference herein) modifies or supersedes such statement. Any such statement so modified or superseded
shall not be deemed, except as so modified or superseded, to constitute a part of this Registration Statement.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0">Item 5. Interests of Named Experts and Counsel.</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">Not applicable.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in"></P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0">Item 8. Exhibits.</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="5" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: bottom">
    <TD STYLE="width: 9%; border-bottom: Black 1pt solid; text-align: center; font-size: 8pt; font-weight: bold">Exhibit Number</TD>
    <TD STYLE="width: 91%; text-align: center; font-size: 8pt; font-weight: bold">&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: top; text-align: center">4.1</TD>
    <TD STYLE="vertical-align: bottom">Articles of Association of Auris Medical Holding AG (incorporated by reference to exhibit 4.1 of the Registration Statement on Form F-3 filed with the Commission on April 14, 2017)</TD></TR>
<TR>
    <TD STYLE="vertical-align: top; text-align: center">4.2</TD>
    <TD STYLE="vertical-align: bottom">Form of Registration Rights Agreement (incorporated herein by reference to Exhibit 4.1 to the Registrant&rsquo;s Registration Statement on Form F-1/A, filed with the Commission on July 21, 2014 (Registration File No. 333-197105))</TD></TR>
<TR>
    <TD STYLE="vertical-align: top; text-align: center">5</TD>
    <TD STYLE="vertical-align: bottom">Opinion of Walder Wyss Ltd., Swiss counsel to the Registrant (filed herewith)</TD></TR>
<TR>
    <TD STYLE="vertical-align: top; text-align: center">23.1</TD>
    <TD STYLE="vertical-align: bottom">Consent of Deloitte AG (filed herewith)</TD></TR>
<TR>
    <TD STYLE="vertical-align: top; text-align: center">23.2</TD>
    <TD STYLE="vertical-align: bottom">Consent of Walder Wyss Ltd., Swiss counsel to the Registrant (included in Exhibit 5) </TD></TR>
<TR>
    <TD STYLE="vertical-align: top; text-align: center">24</TD>
    <TD STYLE="vertical-align: bottom">Power of Attorney (included in the signature pages hereof)</TD></TR>
<TR>
    <TD STYLE="vertical-align: top; text-align: center">99.1</TD>
    <TD STYLE="vertical-align: bottom">Auris Medical Holding AG Equity Incentive Plan, as amended (filed herewith)</TD></TR>
</TABLE>

<P STYLE="margin-top: 0; margin-bottom: 0">&nbsp;</P>

<P STYLE="margin-top: 0; margin-bottom: 0">&nbsp;</P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase"><B>Signatures</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">Pursuant to the requirements of the Securities
Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing
this Registration Statement and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto
duly authorized, in Zug, Switzerland on this 14<SUP>th</SUP> day of April, 2017.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" ALIGN="RIGHT" STYLE="width: 35%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD COLSPAN="2">Auris Medical Holding AG</TD></TR>
<TR STYLE="vertical-align: top">
    <TD COLSPAN="2">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD COLSPAN="2">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 14%">By:</TD>
    <TD STYLE="width: 86%; border-bottom: Black 1pt solid">/s/ Thomas Meyer</TD></TR>
<TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD>Name:&#9;Thomas Meyer</TD></TR>
<TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD>Title:&#9;Chief Executive Officer</TD></TR>
</TABLE><BR STYLE="clear: both">

<P STYLE="margin-top: 0; margin-bottom: 0">&nbsp;</P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center; text-indent: 0.25in"><B>POWER OF ATTORNEY</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">KNOW ALL PERSONS BY THESE PRESENTS, that
each person whose signature appears below hereby constitutes and appoints Thomas Meyer, Hernan Levett and Anne Sabine Zoller and
each of them, individually, as his or her true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution,
for him or her and in his or her name, place and stead in any and all capacities, in connection with this Registration Statement,
including to sign in the name and on behalf of the undersigned, this Registration Statement and any and all amendments thereto,
including post-effective amendments and registrations filed pursuant to Rule 462 under the U.S. Securities Act of 1933, and to
file the same, with all exhibits thereto, and other documents in connection therewith, with the U.S. Securities and Exchange Commission,
granting unto such attorneys-in-fact and agents full power and authority to do and perform each and every act and thing requisite
and necessary to be done in and about the premises, as fully to all intents and purposes as he or she might or could do in person,
hereby ratifying and confirming all that said attorneys-in-fact and agents or either of them or their substitute or substitutes,
may lawfully do or cause to be done by virtue hereof.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">Pursuant to the requirements of the Securities
Act of 1933, as amended, this Registration Statement has been signed by the following persons in the capacities and on the dates
indicated:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font-size: 10pt; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 33%; padding-right: 3pt; padding-left: 3pt; text-align: center">
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; border-bottom: Black 0.5pt solid; margin-bottom: 0pt; text-align: center"><B>Name</B></P></TD>
    <TD STYLE="width: 42%; padding-right: 3pt; padding-left: 3pt">
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center; border-bottom: Black 0.5pt solid"><B>Title</B></P></TD>
    <TD STYLE="width: 25%; padding-right: 3pt; padding-left: 3pt">
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center; border-bottom: Black 0.5pt solid"><B>Date</B></P></TD></TR>
<TR>
    <TD STYLE="padding-right: 3pt; padding-left: 3pt; text-align: center">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: center; padding-right: 3pt; padding-left: 3pt">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: center; text-indent: 30.6pt; padding-right: 3pt; padding-left: 3pt">&nbsp;</TD></TR>
<TR>
    <TD STYLE="border-bottom: Black 1pt solid; padding-right: 3pt; padding-left: 3pt; text-align: center">
/s/ Thomas Meyer</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: center; padding-right: 3pt; padding-left: 3pt">Chief Executive Officer and Director</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: center; text-indent: 30.6pt; padding-right: 3pt; padding-left: 3pt">April
    14, 2017</TD></TR>
<TR>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: center; padding-right: 3pt; padding-left: 3pt">Thomas Meyer</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: center; padding-right: 3pt; padding-left: 3pt">(principal executive officer)</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: center; text-indent: 30.6pt; padding-right: 3pt; padding-left: 3pt">&nbsp;</TD></TR>
</TABLE>


<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font-size: 10pt; width: 100%; border-collapse: collapse">
<TR>
    <TD STYLE="border-bottom: Black 1pt solid; width: 33%; padding-right: 3pt; padding-left: 3pt; text-align: center">/s/ Hernan Levett</TD>
    <TD STYLE="width: 42%; font: 10pt Times New Roman, Times, Serif; text-align: center; padding-right: 3pt; padding-left: 3pt">Chief Financial Officer</TD>
    <TD STYLE="width: 25%; font: 10pt Times New Roman, Times, Serif; text-align: center; text-indent: 30.6pt; padding-right: 3pt; padding-left: 3pt">April
    14, 2017</TD></TR>
<TR>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: center; vertical-align: top; padding-right: 3pt; padding-left: 3pt">Hernan Levett</TD>
    <TD STYLE="padding-right: 3pt; padding-left: 3pt">
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"></P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(principal financial officer and</P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">principal accounting officer)</P></TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: center; text-indent: 30.6pt; vertical-align: top; padding-right: 3pt; padding-left: 3pt"></TD></TR>
</TABLE>


<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">&nbsp;&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
<TR>
    <TD STYLE="border-bottom: Black 1pt solid; text-align: center; vertical-align: top">/s/ Armando Anido</TD>
    <TD STYLE="text-align: center; vertical-align: top">Director</TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top">April
    14, 2017</TD></TR>
<TR>
    <TD STYLE="width: 33%; text-align: center; vertical-align: top">Armando Anido</TD>
    <TD STYLE="width: 42%; text-align: center; vertical-align: top"></TD>
    <TD STYLE="width: 25%; text-align: center; text-indent: 30.6pt; vertical-align: top"></TD></TR>
<TR>
    <TD STYLE="text-align: center; vertical-align: top">&nbsp;</TD>
    <TD STYLE="text-align: center; vertical-align: top">&nbsp;</TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top">&nbsp;</TD></TR>
<TR>
    <TD STYLE="border-bottom: Black 1pt solid; text-align: center; vertical-align: top">/s/ Oliver Kubli</TD>
    <TD STYLE="text-align: center; vertical-align: top">Director</TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top">April
    14, 2017</TD></TR>
<TR>
    <TD STYLE="text-align: center; vertical-align: top">Oliver Kubli</TD>
    <TD STYLE="text-align: center; vertical-align: top"></TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top"></TD></TR>
<TR>
    <TD STYLE="text-align: center; vertical-align: top">&nbsp;</TD>
    <TD STYLE="text-align: center; vertical-align: top">&nbsp;</TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top">&nbsp;</TD></TR>
<TR>
    <TD STYLE="border-bottom: Black 1pt solid; text-align: center; vertical-align: top">/s/ Berndt A.E. Modig</TD>
    <TD STYLE="text-align: center; vertical-align: top">Director</TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top">April
    14, 2017</TD></TR>
<TR>
    <TD STYLE="text-align: center; vertical-align: top">Berndt A.E. Modig</TD>
    <TD STYLE="text-align: center; vertical-align: top"></TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top"></TD></TR>
<TR>
    <TD STYLE="text-align: center; vertical-align: top">&nbsp;</TD>
    <TD STYLE="text-align: center; vertical-align: top">&nbsp;</TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top">&nbsp;</TD></TR>
<TR>
    <TD STYLE="border-bottom: Black 1pt solid; text-align: center; vertical-align: top">/s/ Antoine Papiernik</TD>
    <TD STYLE="text-align: center; vertical-align: top">Director</TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top">April
    14, 2017</TD></TR>
<TR>
    <TD STYLE="text-align: center; vertical-align: top">Antoine Papiernik</TD>
    <TD STYLE="text-align: center; vertical-align: top"></TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top"></TD></TR>
<TR>
    <TD STYLE="text-align: center; vertical-align: top">&nbsp;</TD>
    <TD STYLE="text-align: center; vertical-align: top">&nbsp;</TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top">&nbsp;</TD></TR>
<TR>
    <TD STYLE="border-bottom: Black 1pt solid; text-align: center; vertical-align: top">/s/ Calvin Roberts</TD>
    <TD STYLE="text-align: center; vertical-align: top">Director</TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top">April
    14, 2017</TD></TR>
<TR>
    <TD ROWSPAN="2" STYLE="text-align: center; vertical-align: top">Calvin Roberts</TD>
    <TD STYLE="text-align: center; vertical-align: top"></TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top"></TD></TR>
<TR>
    <TD STYLE="text-align: center; vertical-align: top">&nbsp;</TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top">&nbsp;</TD></TR>
<TR>
    <TD STYLE="text-align: center; vertical-align: top">&nbsp;</TD>
    <TD STYLE="text-align: center; vertical-align: top">&nbsp;</TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top">&nbsp;</TD></TR>
<TR>
    <TD STYLE="border-bottom: Black 1pt solid; text-align: center; vertical-align: top"></TD>
    <TD STYLE="text-align: center; vertical-align: top">Director</TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top">April
    14, 2017</TD></TR>
<TR>
    <TD ROWSPAN="2" STYLE="text-align: center; vertical-align: top">Mats Peter Blom</TD>
    <TD STYLE="text-align: center; vertical-align: top"></TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top"></TD></TR>
<TR>
    <TD STYLE="text-align: center; vertical-align: top">&nbsp;</TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top">&nbsp;</TD></TR>
<TR>
    <TD STYLE="text-align: center; vertical-align: top">&nbsp;</TD>
    <TD STYLE="text-align: center; vertical-align: top">&nbsp;</TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top">&nbsp;</TD></TR>
<TR>
    <TD STYLE="border-bottom: Black 1pt solid; text-align: center; vertical-align: top">/s/ Colleen A. DeVries</TD>
    <TD STYLE="text-align: center; vertical-align: top">SVP of National Corporate Research, Ltd.</TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top">April
    14, 2017</TD></TR>
<TR>
    <TD STYLE="text-align: center; vertical-align: top">Colleen A. DeVries</TD>
    <TD STYLE="text-align: center; vertical-align: top">
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Authorized Representative in the</P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">United States</P></TD>
    <TD STYLE="text-align: center; text-indent: 30.6pt; vertical-align: top"></TD></TR>
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<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">EXHIBIT INDEX</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="5" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: bottom">
    <TD STYLE="width: 9%; border-bottom: Black 1pt solid; text-align: center; font-size: 8pt; font-weight: bold">Exhibit Number</TD>
    <TD STYLE="width: 91%; text-align: center; font-size: 8pt; font-weight: bold">&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: top; text-align: center">4.1</TD>
    <TD STYLE="vertical-align: bottom">Articles of Association of Auris Medical Holding AG (incorporated by reference to exhibit 4.1 of the Registration Statement on Form F-3 filed with the Commission on April 14, 2017)</TD></TR>
<TR>
    <TD STYLE="vertical-align: top; text-align: center">4.2</TD>
    <TD STYLE="vertical-align: bottom">Form of Registration Rights Agreement (incorporated herein by reference to Exhibit 4.1 to the Registrant&rsquo;s Registration Statement on Form F-1/A, filed with the Commission on July 21, 2014 (Registration File No. 333-197105))</TD></TR>
<TR>
    <TD STYLE="vertical-align: top; text-align: center">5</TD>
    <TD STYLE="vertical-align: bottom">Opinion of Walder Wyss Ltd., Swiss counsel to the Registrant (filed herewith)</TD></TR>
<TR>
    <TD STYLE="vertical-align: top; text-align: center">23.1</TD>
    <TD STYLE="vertical-align: bottom">Consent of Deloitte AG (filed herewith)</TD></TR>
<TR>
    <TD STYLE="vertical-align: top; text-align: center">23.2</TD>
    <TD STYLE="vertical-align: bottom">Consent of Walder Wyss Ltd., Swiss counsel to the Registrant (included in Exhibit 5) </TD></TR>
<TR>
    <TD STYLE="vertical-align: top; text-align: center">24</TD>
    <TD STYLE="vertical-align: bottom">Power of Attorney (included in the signature pages hereof)</TD></TR>
<TR>
    <TD STYLE="vertical-align: top; text-align: center">99.1</TD>
    <TD STYLE="vertical-align: bottom">Auris Medical Holding AG Equity Incentive Plan, as amended (filed herewith)</TD></TR>
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[{"type": "S-8", "sequence": "1", "filename": "dp75080_s8.htm", "description": "FORM S-8", "secsgml_size_bytes": 39783}]
{"company-data": {"conformed-name": "Auris Medical Holding AG", "cik": "0001601936", "assigned-sic": "2834", "irs-number": "000000000", "state-of-incorporation": "V8", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-217306", "film-number": "17762153"}, "business-address": {"street1": "FALKNERSTRASSE 4", "city": "4001 BASEL", "state": "V8", "zip": "00000", "phone": "41 (0)61 201 13 50"}, "mail-address": {"street1": "FALKNERSTRASSE 4", "city": "4001 BASEL", "state": "V8", "zip": "00000"}, "former-company": {"former-conformed-name": "Auris Medical AG", "date-changed": "20140306"}}
As filed with the Securities and Exchange
Commission on April 14, 2017
Registration
No. 333-______
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-8
REGISTRATION STATEMENT
UNDER THE SECURITIES ACT OF 1933
Auris Medical Holding AG
(Exact Name of Registrant as Specified in
Its Charter)
Switzerland
Not Applicable
(State or Other Jurisdiction of
Incorporation or Organization)
(I.R.S. Employer
Identification Number)
Bahnhofstrasse 21
6300 Zug
Switzerland
(Address,
Including Zip Code of Principal Executive Offices)
Auris Medical Holding AG Equity Incentive Plan, as amended
(Full title of Plans)
National Corporate Research, Ltd.
10 East 40
th
Street
New York, New York 10016
(212) 947-7200
(Name, address and telephone number, including area code, of agent for service)
Copies to:
Sophia Hudson
Davis Polk & Wardwell LLP
450 Lexington Avenue
New York, New York 10017
(212) 450-4000
Indicate by check mark whether the registrant
is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions
of "large accelerated filer," "accelerated filer" and "smaller reporting company" in Rule 12b-2
of the Exchange Act.
Large accelerated filer
☐
Accelerated
filer
☐
Non-accelerated filer
☒
(Do not check if a smaller reporting company)	       Smaller reporting company
☐
CALCULATION OF REGISTRATION FEE
Title Of Securities To Be Registered
Amount To Be Registered(1)
Proposed Maximum Offering Price Per Share(2)
Proposed Maximum Aggregate Offering Price(2)
Amount Of
Registration Fee
Common Shares, nominal value CHF 0.40 per share
5,141,000
$0.72
$3,701,520
$429.01
(1)
This Registration Statement on Form S-8 (this "Registration Statement") covers (i) common shares, nominal value
CHF 0.40 per share ("Common Shares"), of Auris Medical Holding AG (the "Registrant"), issuable pursuant
to the Auris Medical Holding AG Equity Incentive Plan, as amended (the "EIP"); and (ii) pursuant to Rule 416(a) under
the Securities Act of 1933, as amended (the "Securities Act"), any additional Common Shares that become issuable under
the EIP by reason of any share dividend, share split or other similar transaction.
(2)
Estimated pursuant to Rule 457(h) and Rule 457(c) under the Securities Act, solely for the purpose of computing the registration
fee for Common Shares to be issued pursuant to the EIP, based on the average of the high and low prices reported for a Common Share
on the NASDAQ Global Select Market on April 7, 2017.
EXPLANATORY NOTE
This Registration Statement has been prepared
and filed pursuant to and in accordance with the requirements of General Instruction E to Form S-8 for the purpose of registering
an additional 5,141,000 Common Shares that are issuable at any time or from time to time under the EIP. Pursuant to General Instruction
E, the contents of the Registration Statement on Form S-8 filed for the EIP with the U.S. Securities and Exchange Commission (the
"Commission") on December 8, 2014 (Registration File No. 333-200805), including the documents incorporated by reference
therein, are incorporated by reference into this Registration Statement, except as supplemented by the information set forth below.
PART I
INFORMATION REQUIRED IN THE SECTION
10(a) PROSPECTUS
The documents containing the information
specified in Item 1 and Item 2 of Part I of Form S-8 will be delivered to participants as specified by Rule 428(b)(1) under the
Securities Act. In accordance with the rules and regulations of the Commission and the instructions to Form S-8, such documents
are not being filed with the Commission either as part of this Registration Statement or as prospectuses or prospectus supplements
pursuant to Rule 424 under the Securities Act.
PART II
INFORMATION REQUIRED IN THE REGISTRATION
STATEMENT
Item 3. Incorporation of Documents by Reference.
The following documents are incorporated
herein by reference:
(a)       The
Registrant's Annual Report on Form 20-F for the fiscal year ended December 31, 2016, filed with the Commission on March 14,
2017 (Registration File No. 001-36582).
(b)       All
reports filed pursuant to Section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended (the "Exchange Act"),
since December 31, 2016.
(c)
       The description of the Registrant's Common Shares which is contained in the
Registrant's Exchange Act Registration Statement on Form 8-A (Registration File No. 001-36582), dated July 29, 2014 and
amended on June 1, 2016, including any amendments or supplements thereto or report filed for the purpose of updating such
description.
In addition, all documents subsequently
filed by the Registrant with the Commission pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act, prior to the filing
of a post-effective amendment to this Registration Statement which indicates that all securities offered have been sold or which
deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference in this Registration Statement
and to be a part hereof from the date of the filing of such documents.
Any statement contained in a document incorporated
or deemed to be incorporated by reference herein shall be deemed to be modified or superseded for purposes of this Registration
Statement to the extent that a statement contained herein (or in any other subsequently filed document which also is incorporated
or deemed to be incorporated by reference herein) modifies or supersedes such statement. Any such statement so modified or superseded
shall not be deemed, except as so modified or superseded, to constitute a part of this Registration Statement.
Item 5. Interests of Named Experts and Counsel.
Not applicable.
Item 8. Exhibits.
Exhibit Number
4.1
Articles of Association of Auris Medical Holding AG (incorporated by reference to exhibit 4.1 of the Registration Statement on Form F-3 filed with the Commission on April 14, 2017)
4.2
Form of Registration Rights Agreement (incorporated herein by reference to Exhibit 4.1 to the Registrant's Registration Statement on Form F-1/A, filed with the Commission on July 21, 2014 (Registration File No. 333-197105))
5
Opinion of Walder Wyss Ltd., Swiss counsel to the Registrant (filed herewith)
23.1
Consent of Deloitte AG (filed herewith)
23.2
Consent of Walder Wyss Ltd., Swiss counsel to the Registrant (included in Exhibit 5)
24
Power of Attorney (included in the signature pages hereof)
99.1
Auris Medical Holding AG Equity Incentive Plan, as amended (filed herewith)
Signatures
Pursuant to the requirements of the Securities
Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing
this Registration Statement and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto
duly authorized, in Zug, Switzerland on this 14
th
day of April, 2017.
Auris Medical Holding AG
By:
/s/ Thomas Meyer
Name:	Thomas Meyer
Title:	Chief Executive Officer
POWER OF ATTORNEY
KNOW ALL PERSONS BY THESE PRESENTS, that
each person whose signature appears below hereby constitutes and appoints Thomas Meyer, Hernan Levett and Anne Sabine Zoller and
each of them, individually, as his or her true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution,
for him or her and in his or her name, place and stead in any and all capacities, in connection with this Registration Statement,
including to sign in the name and on behalf of the undersigned, this Registration Statement and any and all amendments thereto,
including post-effective amendments and registrations filed pursuant to Rule 462 under the U.S. Securities Act of 1933, and to
file the same, with all exhibits thereto, and other documents in connection therewith, with the U.S. Securities and Exchange Commission,
granting unto such attorneys-in-fact and agents full power and authority to do and perform each and every act and thing requisite
and necessary to be done in and about the premises, as fully to all intents and purposes as he or she might or could do in person,
hereby ratifying and confirming all that said attorneys-in-fact and agents or either of them or their substitute or substitutes,
may lawfully do or cause to be done by virtue hereof.
Pursuant to the requirements of the Securities
Act of 1933, as amended, this Registration Statement has been signed by the following persons in the capacities and on the dates
indicated:
Name
Title
Date
/s/ Thomas Meyer
Chief Executive Officer and Director
April
    14, 2017
Thomas Meyer
(principal executive officer)
/s/ Hernan Levett
Chief Financial Officer
April
    14, 2017
Hernan Levett
(principal financial officer and
principal accounting officer)
/s/ Armando Anido
Director
April
    14, 2017
Armando Anido
/s/ Oliver Kubli
Director
April
    14, 2017
Oliver Kubli
/s/ Berndt A.E. Modig
Director
April
    14, 2017
Berndt A.E. Modig
/s/ Antoine Papiernik
Director
April
    14, 2017
Antoine Papiernik
/s/ Calvin Roberts
Director
April
    14, 2017
Calvin Roberts
Director
April
    14, 2017
Mats Peter Blom
/s/ Colleen A. DeVries
SVP of National Corporate Research, Ltd.
April
    14, 2017
Colleen A. DeVries
Authorized Representative in the
United States
EXHIBIT INDEX
Exhibit Number
4.1
Articles of Association of Auris Medical Holding AG (incorporated by reference to exhibit 4.1 of the Registration Statement on Form F-3 filed with the Commission on April 14, 2017)
4.2
Form of Registration Rights Agreement (incorporated herein by reference to Exhibit 4.1 to the Registrant's Registration Statement on Form F-1/A, filed with the Commission on July 21, 2014 (Registration File No. 333-197105))
5
Opinion of Walder Wyss Ltd., Swiss counsel to the Registrant (filed herewith)
23.1
Consent of Deloitte AG (filed herewith)
23.2
Consent of Walder Wyss Ltd., Swiss counsel to the Registrant (included in Exhibit 5)
24
Power of Attorney (included in the signature pages hereof)
99.1
Auris Medical Holding AG Equity Incentive Plan, as amended (filed herewith)