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<TITLE>S-8 Registration Statement</TITLE>
<META NAME="author" CONTENT="Justeene Blankenship">
<META NAME="date" CONTENT="10/12/2016">
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<P style="margin:0px" align=center><B>As filed with the Securities and Exchange Commission on October 14, 2016</B></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px" align=right>Registration No. &nbsp;333-____________</P>
<P style="margin:0px" align=center><B>___________________________________________________________________________________________________________</B></P>
<P style="margin:0px" align=center><BR></P>
<P style="margin:0px" align=center><B>UNITED STATES</B></P>
<P style="margin:0px" align=center><B>SECURITIES AND EXCHANGE COMMISSION</B></P>
<P style="margin:0px" align=center><B>WASHINGTON, D.C. 20549</B></P>
<P style="margin:0px" align=center><U>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U></P>
<P style="margin:0px" align=center><BR></P>
<P style="margin:0px; font-size:12pt" align=center><B>FORM S-8</B></P>
<P style="margin:0px" align=center><B>REGISTRATION STATEMENT</B></P>
<P style="margin:0px" align=center><B>UNDER</B></P>
<P style="margin:0px" align=center><B>THE SECURITIES ACT OF 1933</B></P>
<P style="margin:0px" align=center><U>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U></P>
<P style="margin:0px" align=center><BR></P>
<P style="margin:0px; font-size:14pt" align=center><B>VOLITIONRX LIMITED</B></P>
<P style="margin:0px; padding-left:48px" align=center>(Exact name of registrant as specified in its charter)</P>
<P style="margin:0px" align=center><BR></P>
<TABLE style="margin-top:0px; font-size:10pt" cellpadding=0 cellspacing=0 align=center><TR height=0 style="font-size:0"><TD width=355.2 /><TD width=283.2 /></TR>
<TR><TD style="margin-top:0px" valign=top width=355.2><P style="margin:0px" align=center><B>Delaware</B></P>
</TD><TD style="margin-top:0px" valign=top width=283.2><P style="margin:0px" align=center><B>91-1949078</B></P>
</TD></TR>
<TR><TD style="margin-top:0px" valign=top width=355.2><P style="margin:0px" align=center>(State or other jurisdiction of<BR>
incorporation or organization)</P>
</TD><TD style="margin-top:0px" valign=top width=283.2><P style="margin:0px" align=center>(I.R.S. Employer<BR>
Identification Number)</P>
</TD></TR>
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<P style="margin:0px" align=center><U>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U></P>
<P style="margin:0px" align=center><BR></P>
<P style="margin:0px" align=center><B>1 Scotts Road</B></P>
<P style="margin:0px" align=center><B>#24-05 Shaw Centre</B></P>
<P style="margin:0px" align=center><B>Singapore 228208</B></P>
<P style="margin:0px" align=center>(Address of Principal Executive Offices; Zip Code)</P>
<P style="margin:0px" align=center>____________________________</P>
<P style="margin:0px" align=center><BR></P>
<P style="margin:0px" align=center><B>VolitionRx 2015 Stock Incentive Plan, as amended</B></P>
<P style="margin:0px" align=center>(Full title of the plan)</P>
<P style="margin:0px" align=center>____________________________</P>
<P style="margin:0px" align=center><BR></P>
<P style="margin:0px" align=center><B>Agents and Corporations, Inc.</B></P>
<P style="margin:0px" align=center><B>1201 Orange Street, Suite 600</B></P>
<P style="margin:0px" align=center><B>Wilmington, Delaware 19899</B></P>
<P style="margin:0px" align=center>(Name and address of agent for service)</P>
<P style="margin:0px" align=center><BR></P>
<P style="margin:0px" align=center><B>+1 (646) 650-1351</B></P>
<P style="margin:0px" align=center>(Telephone number, including area code, of agent for service)</P>
<P style="margin:0px" align=center><U>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U></P>
<P style="margin:0px" align=center><BR></P>
<P style="margin:0px" align=center><B>Copies to:</B></P>
<P style="margin:0px" align=center><B>Marc G. Alcser</B></P>
<P style="margin:0px" align=center><B>Peter Dansie</B></P>
<P style="margin:0px" align=center><B>Stradling Yocca Carlson &amp; Rauth</B></P>
<P style="margin:0px" align=center><B>660 Newport Center Drive, Suite 1600</B></P>
<P style="margin:0px" align=center><B>Newport Beach, California 92660</B></P>
<P style="margin:0px" align=center><B>(949) 725-4000</B></P>
<P style="margin:0px" align=center><U>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px" align=justify>Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company.&nbsp;See the definitions of &#147;large accelerated filer,&#148; &#147;accelerated filer,&#148; and &#147;smaller reporting company&#148; in </P>
<P style="margin:0px" align=justify>Rule&nbsp;12b-2 of the Exchange Act. &nbsp;(Check one):</P>
<P style="margin:0px"><BR></P>
<P style="margin-top:0px; margin-bottom:-2px; text-indent:48px; width:216px; float:left">Large accelerated filer<FONT style="font-size:11.5pt"> </FONT><FONT style="margin-bottom:1.333px; padding-top:1.333px; font-size:6pt; border:1px solid #000000">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</FONT><FONT style="font-size:6pt; color:#FFFFFF">.</FONT></P>
<P style="margin-top:0px; margin-bottom:-2px; width:132px; float:left">Accelerated filer<FONT style="font-size:11.5pt"> </FONT><FONT style="margin-bottom:1.333px; padding-top:1.333px; font-size:6pt; border:1px solid #000000">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</FONT><FONT style="font-size:6pt; color:#FFFFFF">.</FONT></P>
<P style="margin-top:0px; margin-bottom:-2px; width:156px; float:left">Non-accelerated filer<FONT style="font-size:11.5pt"> </FONT><FONT style="margin-bottom:1.333px; padding-top:1.333px; font-size:6pt; border:1px solid #000000">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</FONT><FONT style="font-size:6pt; color:#FFFFFF">.</FONT></P>
<P style="margin:0px; padding-left:48px; text-indent:-2px">Smaller reporting company<FONT style="font-size:11.5pt"> </FONT><FONT style="margin-bottom:1.333px; padding-top:1.333px; font-size:6pt; border:1px solid #000000">&nbsp;X </FONT><FONT style="font-size:6pt; color:#FFFFFF">.</FONT></P>
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<BR></P>
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<P style="margin:0px" align=center><B>CALCULATION OF REGISTRATION FEE </B></P>
<P style="margin:0px" align=center><BR></P>
<TABLE style="margin-top:0px; font-size:10pt" cellpadding=0 cellspacing=0 align=center><TR height=0 style="font-size:0"><TD width=234 /><TD width=106.333 /><TD width=128.267 /><TD width=117.333 /><TD width=117.333 /></TR>
<TR><TD style="margin-top:0px; border:1px solid #000000" valign=bottom width=234><P style="margin:0px" align=center><B>Title of Each Class of Securities to be</B></P>
<P style="margin:0px" align=center><B>Registered</B></P>
</TD><TD style="margin-top:0px; border-top:1px solid #000000; border-right:1px solid #000000; border-bottom:1px solid #000000" valign=bottom width=106.333><P style="margin:0px" align=center><B>Amount to be </B></P>
<P style="margin:0px" align=center><B>Registered<SUP>(1)(2)</SUP></B></P>
</TD><TD style="margin-top:0px; border-top:1px solid #000000; border-right:1px solid #000000; border-bottom:1px solid #000000" valign=bottom width=128.267><P style="margin:0px" align=center><B>Proposed Maximum</B></P>
<P style="margin:0px" align=center><B>Offering</B></P>
<P style="margin:0px" align=center><B>Price Per Share<SUP>(3)</SUP></B></P>
</TD><TD style="margin-top:0px; border-top:1px solid #000000; border-right:1px solid #000000; border-bottom:1px solid #000000" valign=bottom width=117.333><P style="margin:0px" align=center><B>Proposed Maximum</B></P>
<P style="margin:0px" align=center><B>Aggregate Offering</B></P>
<P style="margin:0px" align=center><B>&nbsp;Price<SUP>(3)</SUP></B></P>
</TD><TD style="margin-top:0px; border-top:1px solid #000000; border-right:1px solid #000000; border-bottom:1px solid #000000" valign=bottom width=117.333><P style="margin:0px" align=center><B>Amount of </B></P>
<P style="margin:0px" align=center><B>Registration Fee<SUP>(3)</SUP></B></P>
</TD></TR>
<TR><TD style="margin-top:0px; border-left:1px solid #000000; border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=234><P style="margin:0px"><BR></P>
<P style="margin:0px">Common Stock, par value $0.001 per share</P>
</TD><TD style="margin-top:0px; border-right:1px solid #000000; border-bottom:1px solid #000000" valign=bottom width=106.333><P style="margin:0px" align=center>750,000</P>
</TD><TD style="margin-top:0px; border-right:1px solid #000000; border-bottom:1px solid #000000" valign=bottom width=128.267><P style="margin:0px" align=center>$4.87</P>
</TD><TD style="margin-top:0px; border-right:1px solid #000000; border-bottom:1px solid #000000" valign=bottom width=117.333><P style="margin:0px" align=center>$3,652,500</P>
</TD><TD style="margin-top:0px; border-right:1px solid #000000; border-bottom:1px solid #000000" valign=bottom width=117.333><P style="margin:0px" align=center>$423.32</P>
</TD></TR>
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<P style="margin:0px"><BR></P>
<P style="margin-top:0px; margin-bottom:-2px; width:48px; float:left">(1)</P>
<P style="margin:0px; padding-left:48px; text-indent:-2px" align=justify>Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the &#147;Securities Act&#148;), this Registration Statement shall also cover any additional shares of the registrant&#146;s common stock that become issuable under the registrant&#146;s 2015 Stock Incentive Plan, as amended (the &#147;Plan&#148;), by reason of any stock dividend, stock split, recapitalization or any similar transaction effected without the receipt of consideration that results in an increase in the number of the registrant&#146;s outstanding shares of common stock.</P>
<P style="margin:0px; clear:left" align=justify><BR></P>
<P style="margin-top:0px; margin-bottom:-2px; width:48px; float:left">(2)</P>
<P style="margin:0px; padding-left:48px; text-indent:-2px" align=justify>Represents 750,000 additional shares of the registrant&#146;s common stock reserved for issuance pursuant to the Plan.</P>
<P style="margin:0px; clear:left" align=justify><BR></P>
<P style="margin-top:0px; margin-bottom:-2px; width:48px; float:left">(3)</P>
<P style="margin:0px; padding-left:48px; text-indent:-2px" align=justify>Estimated pursuant to Rule 457(c) and Rule 457(h) of the Securities Act, solely for purposes of calculating the registration fee, which is the average of the high and low sales price of the registrant&#146;s common stock as reported on the NYSE MKT on October 11, 2016.</P>
<P style="margin:0px; clear:left"><BR></P>
<P style="margin:0px"><BR></P>
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<A NAME="_Toc330477780"></A><P style="margin:0px"><BR>
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<P style="line-height:10pt; margin:0px" align=center>2</P>
<P style="line-height:10pt; margin:0px"><BR></P>
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<P style="margin:0px" align=center><B>REGISTRATION OF ADDITIONAL SECURITIES PURSUANT TO GENERAL INSTRUCTION E</B></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px; text-indent:48px" align=justify>Pursuant to General Instruction E to Form S-8, this Registration Statement on Form S-8 (this &#147;Registration Statement&#148;) is being filed for the purpose of registering an additional 750,000 shares of VolitionRx Limited (the &#147;Registrant&#148;) common stock, par value $0.001 per share (&#147;Common Stock&#148;), reserved for issuance under the Registrant&#146;s 2015 Stock Incentive Plan, as amended (the &#147;Plan&#148;), which are the same class as those securities registered on the Registrant&#146;s prior registration statement on Form S-8 (File No. 333-208512), filed with the Securities and Exchange Commission (the &#147;Commission&#148;) on December 11, 2015. &nbsp;The contents of the foregoing registration statement on Form S-8 are incorporated herein by reference.</P>
<P style="margin:0px" align=center><BR></P>
<P style="margin:0px" align=center><B>PART II</B></P>
<P style="margin:0px" align=center><B>INFORMATION REQUIRED IN THE REGISTRATION STATEMENT </B></P>
<P style="margin:0px" align=justify><BR></P>
<P style="margin:0px" align=justify><B>Item 8<I>. &nbsp;</I>Exhibits.</B></P>
<P style="margin:0px" align=justify><BR></P>
<P style="margin:0px; text-indent:48px" align=justify>A list of exhibits filed with this Registration Statement is set forth in the Exhibit Index and is incorporated herein by reference.</P>
<P style="margin:0px" align=justify><BR></P>
<P style="margin:0px" align=justify><BR></P>
<P style="margin:0px" align=justify><BR>
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<P style="line-height:10pt; margin:0px" align=center>3</P>
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<P style="margin:0px" align=center><B>SIGNATURES</B></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px; text-indent:48px" align=justify>Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized in the City of Namur, Belgium, on October 14, 2016.</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px; padding-left:288px">VOLITIONRX LIMITED</P>
<P style="margin:0px"><BR></P>
<P style="margin-top:0px; margin-bottom:-2px; text-indent:288px; width:317.733px; float:left">By:</P>
<P style="margin:0px; padding-left:288px; text-indent:-2px"><I><U>/s/ Cameron Reynolds &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U></I></P>
<P style="margin:0px; padding-left:318px; clear:left">Cameron Reynolds</P>
<P style="margin:0px; padding-left:318px">President, Chief Executive Officer and Director</P>
<P style="margin:0px" align=center><BR></P>
<P style="margin:0px" align=center><B>POWER OF ATTORNEY</B></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px; text-indent:48px" align=justify>KNOW ALL PERSONS BY THESE PRESENTS that each individual whose signature appears below constitutes and appoints Cameron Reynolds and Rodney Rootsaert, and each of them, acting individually, his true and lawful attorneys-in-fact and agent with full power of substitution, for him and in his name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective amendments) to this Registration Statement, and to file the same, with all exhibits thereto and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite and necessary to be done in connection therewith, as fully to all intents and purposes as he might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or either of them, or his or their substitute or substitutes, may lawfully do or cause to be done or by virtue hereof. </P>
<P style="margin:0px"><BR></P>
<P style="margin:0px; text-indent:48px" align=justify>Pursuant to the requirements of the Securities Act, this Registration Statement has been signed by the following persons in the capacities and on the date indicated.</P>
<P style="margin:0px" align=justify><BR></P>
<TABLE style="margin-top:0px; font-size:10pt" cellpadding=0 cellspacing=0><TR height=0 style="font-size:0"><TD width=235.2 /><TD width=276 /><TD width=127.2 /></TR>
<TR><TD style="margin-top:0px" valign=top width=235.2><P style="margin:0px" align=center><U>Signature</U></P>
</TD><TD style="margin-top:0px" valign=top width=276><P style="margin:0px" align=center><U>Title</U></P>
</TD><TD style="margin-top:0px" valign=top width=127.2><P style="margin:0px" align=center><U>Date</U></P>
</TD></TR>
<TR><TD style="margin-top:0px" valign=top width=235.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=276><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=127.2><P style="margin:0px; padding:0px">&nbsp;</P></TD></TR>
<TR><TD style="margin-top:0px" valign=top width=235.2><P style="margin:0px"><I><U>/s/ Cameron Reynolds &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U></I></P>
<P style="margin:0px">Cameron Reynolds</P>
</TD><TD style="margin-top:0px" valign=top width=276><P style="margin:0px">President, Chief Executive Officer and Director</P>
<P style="margin:0px">(Principal Executive Officer)</P>
</TD><TD style="margin-top:0px" valign=top width=127.2><P style="margin:0px">October 14, 2016</P>
</TD></TR>
<TR><TD style="margin-top:0px" valign=top width=235.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=276><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=127.2><P style="margin:0px; padding:0px">&nbsp;</P></TD></TR>
<TR><TD style="margin-top:0px" valign=top width=235.2><P style="margin:0px"><I><U>/s/ David Kratochvil &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U></I></P>
<P style="margin:0px">David Kratochvil</P>
</TD><TD style="margin-top:0px" valign=top width=276><P style="margin:0px">Chief Financial Officer and Treasurer</P>
<P style="margin:0px">(Principal Financial and Accounting Officer)</P>
</TD><TD style="margin-top:0px" valign=top width=127.2><P style="margin:0px">October 14, 2016</P>
</TD></TR>
<TR><TD style="margin-top:0px" valign=top width=235.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=276><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=127.2><P style="margin:0px; padding:0px">&nbsp;</P></TD></TR>
<TR><TD style="margin-top:0px" valign=top width=235.2><P style="margin:0px"><I><U>/s/ Rodney Gerard Rootsaert &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U></I></P>
<P style="margin:0px">Rodney Gerard Rootsaert</P>
</TD><TD style="margin-top:0px" valign=top width=276><P style="margin:0px">Secretary</P>
</TD><TD style="margin-top:0px" valign=top width=127.2><P style="margin:0px">October 14, 2016</P>
</TD></TR>
<TR><TD style="margin-top:0px" valign=top width=235.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=276><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=127.2><P style="margin:0px; padding:0px">&nbsp;</P></TD></TR>
<TR><TD style="margin-top:0px" valign=top width=235.2><P style="margin:0px"><I><U>/s/ Dr. Martin Faulkes &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U></I></P>
<P style="margin:0px">Dr. Martin Faulkes</P>
</TD><TD style="margin-top:0px" valign=top width=276><P style="margin:0px">Director</P>
</TD><TD style="margin-top:0px" valign=top width=127.2><P style="margin:0px">October 14, 2016</P>
</TD></TR>
<TR><TD style="margin-top:0px" valign=top width=235.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=276><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=127.2><P style="margin:0px; padding:0px">&nbsp;</P></TD></TR>
<TR><TD style="margin-top:0px" valign=top width=235.2><P style="margin:0px"><I><U>/s/ Guy Innes &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U></I></P>
<P style="margin:0px">Guy Innes</P>
</TD><TD style="margin-top:0px" valign=top width=276><P style="margin:0px">Director</P>
</TD><TD style="margin-top:0px" valign=top width=127.2><P style="margin:0px">October 14, 2016</P>
</TD></TR>
<TR><TD style="margin-top:0px" valign=top width=235.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=276><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=127.2><P style="margin:0px; padding:0px">&nbsp;</P></TD></TR>
<TR><TD style="margin-top:0px" valign=top width=235.2><P style="margin:0px"><I><U>/s/ Dr. Alan Colman &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U></I></P>
<P style="margin:0px">Dr. Alan Colman</P>
</TD><TD style="margin-top:0px" valign=top width=276><P style="margin:0px">Director</P>
</TD><TD style="margin-top:0px" valign=top width=127.2><P style="margin:0px">October 14, 2016</P>
</TD></TR>
<TR><TD style="margin-top:0px" valign=top width=235.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=276><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=127.2><P style="margin:0px; padding:0px">&nbsp;</P></TD></TR>
<TR><TD style="margin-top:0px" valign=top width=235.2><P style="margin:0px"><I><U>/s/ Dr. Habib Skaff &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U></I></P>
<P style="margin:0px">Dr. Habib Skaff</P>
</TD><TD style="margin-top:0px" valign=top width=276><P style="margin:0px">Director</P>
</TD><TD style="margin-top:0px" valign=top width=127.2><P style="margin:0px">October 14, 2016</P>
</TD></TR>
<TR><TD style="margin-top:0px" valign=top width=235.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=276><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=127.2><P style="margin:0px; padding:0px">&nbsp;</P></TD></TR>
<TR><TD style="margin-top:0px" valign=top width=235.2><P style="margin:0px"><I><U>/s/ Dr. Edward Futcher &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U></I></P>
<P style="margin:0px">Dr. Edward Futcher</P>
</TD><TD style="margin-top:0px" valign=top width=276><P style="margin:0px">Director</P>
</TD><TD style="margin-top:0px" valign=top width=127.2><P style="margin:0px">October 14, 2016</P>
</TD></TR>
</TABLE>
<P style="margin:0px" align=justify><BR></P>
<P style="margin:0px" align=justify><BR></P>
<P style="margin:0px" align=justify><BR>
<BR></P>
<P style="line-height:10pt; margin:0px" align=center>4</P>
<P style="line-height:10pt; margin:0px"><BR></P>
<HR style="margin-bottom:9.6px; padding-top:9.6px" noshade size=1.333>
<P style="margin:0px; page-break-before:always"><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px" align=center><BR></P>
<P style="margin:0px" align=center><B>EXHIBIT INDEX</B></P>
<P style="margin:0px" align=center><BR></P>
<TABLE style="margin-top:0px; font-size:10pt" cellpadding=0 cellspacing=0 align=center><TR height=0 style="font-size:0"><TD width=63.867 /><TD width=5.2 /><TD width=275 /><TD width=16.933 /><TD width=50.133 /><TD width=5.133 /><TD width=77.533 /><TD width=5.133 /><TD width=58.067 /><TD width=5.133 /><TD width=78.8 /><TD width=0.4 /><TD width=4.733 /><TD width=70.533 /></TR>
<TR><TD style="margin-top:0px" valign=bottom width=63.867><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=bottom width=5.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=bottom width=275><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=bottom width=16.933><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px; border-bottom:1.333px solid #000000" valign=bottom width=280.333 colspan=8><P style="margin:0px" align=center><B>Incorporated by Reference</B></P>
</TD><TD style="margin-top:0px" valign=bottom width=75.267 colspan=2><P style="margin:0px; padding:0px">&nbsp;</P></TD></TR>
<TR><TD style="margin-top:0px; border-bottom:1.333px solid #000000" valign=bottom width=63.867><P style="margin:0px" align=center><B>Exhibit Number</B></P>
</TD><TD style="margin-top:0px" valign=bottom width=5.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px; border-bottom:1.333px solid #000000" valign=bottom width=275><P style="margin:0px" align=center><B>Exhibit Description</B></P>
</TD><TD style="margin-top:0px" valign=bottom width=16.933><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px; border-bottom:1.333px solid #000000" valign=bottom width=50.133><P style="margin:0px" align=center><B>Form</B></P>
</TD><TD style="margin-top:0px" valign=bottom width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px; border-bottom:1.333px solid #000000" valign=bottom width=77.533><P style="margin:0px" align=center><B>File No.</B></P>
</TD><TD style="margin-top:0px" valign=bottom width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px; border-bottom:1.333px solid #000000" valign=bottom width=58.067><P style="margin:0px" align=center><B>Exhibit</B></P>
</TD><TD style="margin-top:0px" valign=bottom width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px; border-bottom:1.333px solid #000000" valign=bottom width=78.8><P style="margin:0px" align=center><B>Filing Date</B></P>
</TD><TD style="margin-top:0px" valign=bottom width=5.133 colspan=2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px; border-bottom:1.333px solid #000000" valign=bottom width=70.533><P style="margin:0px" align=center><B>Filed Herewith</B></P>
</TD></TR>
<TR><TD style="margin-top:0px" valign=top width=63.867><P style="margin:0px" align=center>4.1</P>
</TD><TD style="margin-top:0px" valign=top width=5.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=275><P style="margin:0px" align=justify>Second Amended and Restated Certificate of Incorporation.</P>
</TD><TD style="margin-top:0px" valign=top width=16.933><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=50.133><P style="margin:0px" align=center>8-K</P>
</TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=77.533><P style="margin:0px" align=center>001-36833</P>
</TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=58.067><P style="margin:0px" align=center>3.1</P>
</TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=78.8><P style="margin:0px" align=center>10/11/16</P>
</TD><TD style="margin-top:0px" valign=top width=5.133 colspan=2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=70.533><P style="margin:0px; padding:0px">&nbsp;</P></TD></TR>
<TR><TD style="margin-top:0px" valign=top width=63.867><P style="margin:0px" align=center>4.2</P>
</TD><TD style="margin-top:0px" valign=top width=5.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=275><P style="margin:0px" align=justify>Amended and Restated Bylaws.</P>
</TD><TD style="margin-top:0px" valign=top width=16.933><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=50.133><P style="margin:0px" align=center>S-8</P>
</TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=77.533><P style="margin:0px" align=center>333-208512</P>
</TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=58.067><P style="margin:0px" align=center>4.2</P>
</TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=78.8><P style="margin:0px" align=center>12/11/15</P>
</TD><TD style="margin-top:0px" valign=top width=5.133 colspan=2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=70.533><P style="margin:0px; padding:0px">&nbsp;</P></TD></TR>
<TR><TD style="margin-top:0px" valign=top width=63.867><P style="margin:0px" align=center>5.1</P>
</TD><TD style="margin-top:0px" valign=top width=5.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=275><P style="margin:0px" align=justify>Opinion of Stradling Yocca Carlson &amp; Rauth, a Professional Corporation.</P>
</TD><TD style="margin-top:0px" valign=top width=16.933><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=50.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=77.533><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=58.067><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=78.8><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133 colspan=2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=70.533><P style="margin:0px">X</P>
</TD></TR>
<TR><TD style="margin-top:0px" valign=top width=63.867><P style="margin:0px" align=center>10.1</P>
</TD><TD style="margin-top:0px" valign=top width=5.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=275><P style="margin:0px" align=justify>2015 Stock Incentive Plan, as amended.</P>
</TD><TD style="margin-top:0px" valign=top width=16.933><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=50.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=77.533><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=58.067><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=78.8><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133 colspan=2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=70.533><P style="margin:0px">X</P>
</TD></TR>
<TR><TD style="margin-top:0px" valign=top width=63.867><P style="margin:0px" align=center>10.2</P>
</TD><TD style="margin-top:0px" valign=top width=5.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=275><P style="margin:0px" align=justify>Form of Notice of Stock Option Grant and Stock Option Agreement under the 2015 Stock Incentive Plan.</P>
</TD><TD style="margin-top:0px" valign=top width=16.933><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=50.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=77.533><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=58.067><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=78.8><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133 colspan=2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=70.533><P style="margin:0px">X</P>
</TD></TR>
<TR><TD style="margin-top:0px" valign=top width=63.867><P style="margin:0px" align=center>10.3</P>
</TD><TD style="margin-top:0px" valign=top width=5.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=275><P style="margin:0px" align=justify>Form of Notice of Restricted Stock Award and Restricted Stock Agreement under the 2015 Stock Incentive Plan.</P>
</TD><TD style="margin-top:0px" valign=top width=16.933><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=50.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=77.533><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=58.067><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=78.8><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133 colspan=2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=70.533><P style="margin:0px">X</P>
</TD></TR>
<TR><TD style="margin-top:0px" valign=top width=63.867><P style="margin:0px" align=center>10.4</P>
</TD><TD style="margin-top:0px" valign=top width=5.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=275><P style="margin:0px" align=justify>Form of Notice of Stock Bonus Award and Stock Bonus Award Agreement under the 2015 Stock Incentive Plan.</P>
</TD><TD style="margin-top:0px" valign=top width=16.933><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=50.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=77.533><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=58.067><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=78.8><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133 colspan=2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=70.533><P style="margin:0px">X</P>
</TD></TR>
<TR><TD style="margin-top:0px" valign=top width=63.867><P style="margin:0px" align=center>10.5</P>
</TD><TD style="margin-top:0px" valign=top width=5.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=275><P style="margin:0px" align=justify>Form of Notice of Stock Appreciation Right Award and Stock Appreciation Right Award Agreement under the 2015 Stock Incentive Plan.</P>
</TD><TD style="margin-top:0px" valign=top width=16.933><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=50.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=77.533><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=58.067><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=78.8><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133 colspan=2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=70.533><P style="margin:0px">X</P>
</TD></TR>
<TR><TD style="margin-top:0px" valign=top width=63.867><P style="margin:0px" align=center>10.6</P>
</TD><TD style="margin-top:0px" valign=top width=5.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=275><P style="margin:0px" align=justify>Form of Notice of Restricted Stock Unit Award and Restricted Stock Unit Agreement under the 2015 Stock Incentive Plan.</P>
</TD><TD style="margin-top:0px" valign=top width=16.933><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=50.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=77.533><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=58.067><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=78.8><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133 colspan=2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=70.533><P style="margin:0px">X</P>
</TD></TR>
<TR><TD style="margin-top:0px" valign=top width=63.867><P style="margin:0px" align=center>10.7</P>
</TD><TD style="margin-top:0px" valign=top width=5.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=275><P style="margin:0px" align=justify>Form of Notice of Performance Shares Award and Performance Shares Agreement under the 2015 Stock Incentive Plan.</P>
</TD><TD style="margin-top:0px" valign=top width=16.933><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=50.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=77.533><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=58.067><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=78.8><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133 colspan=2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=70.533><P style="margin:0px">X</P>
</TD></TR>
<TR><TD style="margin-top:0px" valign=top width=63.867><P style="margin:0px" align=center>23.1</P>
</TD><TD style="margin-top:0px" valign=top width=5.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=275><P style="margin:0px" align=justify>Consent of Stradling Yocca Carlson &amp; Rauth, a Professional Corporation (contained in Exhibit 5.1).</P>
</TD><TD style="margin-top:0px" valign=top width=16.933><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=50.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=77.533><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=58.067><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=78.8><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133 colspan=2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=70.533><P style="margin:0px">X</P>
</TD></TR>
<TR><TD style="margin-top:0px" valign=top width=63.867><P style="margin:0px" align=center>23.2</P>
</TD><TD style="margin-top:0px" valign=top width=5.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=275><P style="margin:0px" align=justify>Consent of Independent Registered Public Accounting Firm (Sadler, Gibb and Associates, LLC).</P>
</TD><TD style="margin-top:0px" valign=top width=16.933><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=50.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=77.533><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=58.067><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=78.8><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133 colspan=2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=70.533><P style="margin:0px">X</P>
</TD></TR>
<TR><TD style="margin-top:0px" valign=top width=63.867><P style="margin:0px" align=center>24.1</P>
</TD><TD style="margin-top:0px" valign=top width=5.2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=275><P style="margin:0px">Power of Attorney (contained on signature page).</P>
</TD><TD style="margin-top:0px" valign=top width=16.933><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=50.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=77.533><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=58.067><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=78.8><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=5.133 colspan=2><P style="margin:0px; padding:0px">&nbsp;</P></TD><TD style="margin-top:0px" valign=top width=70.533><P style="margin:0px">X</P>
</TD></TR>
</TABLE>
<P style="margin:0px"><BR></P>
<P style="margin:0px" align=right><BR></P>
<P style="margin:0px" align=right><BR>
<BR></P>
<P style="line-height:10pt; margin:0px" align=center>1</P>
<P style="line-height:10pt; margin:0px"><BR></P>
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{"company-data": {"conformed-name": "VOLITIONRX LTD", "cik": "0000093314", "assigned-sic": "2835", "irs-number": "911949078", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-214118", "film-number": "161937235"}, "business-address": {"street1": "1 SCOTTS RD #24-05 SHAW CENTRE", "city": "SINGAPORE", "state": "U0", "zip": "228208", "phone": "1 (646) 650-1351"}, "mail-address": {"street1": "1 SCOTTS RD #24-05 SHAW CENTRE", "city": "SINGAPORE", "state": "U0", "zip": "228208"}, "former-company": {"former-conformed-name": "STANDARD CAPITAL CORP", "date-changed": "19990812"}}
S-8 Registration Statement
As filed with the Securities and Exchange Commission on October 14, 2016
Registration No.  333-____________
___________________________________________________________________________________________________________
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
FORM S-8
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
VOLITIONRX LIMITED
(Exact name of registrant as specified in its charter)
Delaware
91-1949078
(State or other jurisdiction of
incorporation or organization)
(I.R.S. Employer
Identification Number)
1 Scotts Road
#24-05 Shaw Centre
Singapore 228208
(Address of Principal Executive Offices; Zip Code)
____________________________
VolitionRx 2015 Stock Incentive Plan, as amended
(Full title of the plan)
____________________________
Agents and Corporations, Inc.
1201 Orange Street, Suite 600
Wilmington, Delaware 19899
(Name and address of agent for service)
+1 (646) 650-1351
(Telephone number, including area code, of agent for service)
Copies to:
Marc G. Alcser
Peter Dansie
Stradling Yocca Carlson & Rauth
660 Newport Center Drive, Suite 1600
Newport Beach, California 92660
(949) 725-4000
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions of "large accelerated filer," "accelerated filer," and "smaller reporting company" in
Rule 12b-2 of the Exchange Act.  (Check one):
Large accelerated filer
.
Accelerated filer
.
Non-accelerated filer
.
Smaller reporting company
X
.
CALCULATION OF REGISTRATION FEE
Title of Each Class of Securities to be
Registered
Amount to be
Registered
(1)(2)
Proposed Maximum
Offering
Price Per Share
(3)
Proposed Maximum
Aggregate Offering
Price
(3)
Amount of
Registration Fee
(3)
Common Stock, par value $0.001 per share
750,000
$4.87
$3,652,500
$423.32
(1)
Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the "Securities Act"), this Registration Statement shall also cover any additional shares of the registrant's common stock that become issuable under the registrant's 2015 Stock Incentive Plan, as amended (the "Plan"), by reason of any stock dividend, stock split, recapitalization or any similar transaction effected without the receipt of consideration that results in an increase in the number of the registrant's outstanding shares of common stock.
(2)
Represents 750,000 additional shares of the registrant's common stock reserved for issuance pursuant to the Plan.
(3)
Estimated pursuant to Rule 457(c) and Rule 457(h) of the Securities Act, solely for purposes of calculating the registration fee, which is the average of the high and low sales price of the registrant's common stock as reported on the NYSE MKT on October 11, 2016.
2
REGISTRATION OF ADDITIONAL SECURITIES PURSUANT TO GENERAL INSTRUCTION E
Pursuant to General Instruction E to Form S-8, this Registration Statement on Form S-8 (this "Registration Statement") is being filed for the purpose of registering an additional 750,000 shares of VolitionRx Limited (the "Registrant") common stock, par value $0.001 per share ("Common Stock"), reserved for issuance under the Registrant's 2015 Stock Incentive Plan, as amended (the "Plan"), which are the same class as those securities registered on the Registrant's prior registration statement on Form S-8 (File No. 333-208512), filed with the Securities and Exchange Commission (the "Commission") on December 11, 2015.  The contents of the foregoing registration statement on Form S-8 are incorporated herein by reference.
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 8
.
Exhibits.
A list of exhibits filed with this Registration Statement is set forth in the Exhibit Index and is incorporated herein by reference.
3
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized in the City of Namur, Belgium, on October 14, 2016.
VOLITIONRX LIMITED
By:
/s/ Cameron Reynolds
Cameron Reynolds
President, Chief Executive Officer and Director
POWER OF ATTORNEY
KNOW ALL PERSONS BY THESE PRESENTS that each individual whose signature appears below constitutes and appoints Cameron Reynolds and Rodney Rootsaert, and each of them, acting individually, his true and lawful attorneys-in-fact and agent with full power of substitution, for him and in his name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective amendments) to this Registration Statement, and to file the same, with all exhibits thereto and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite and necessary to be done in connection therewith, as fully to all intents and purposes as he might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or either of them, or his or their substitute or substitutes, may lawfully do or cause to be done or by virtue hereof.
Pursuant to the requirements of the Securities Act, this Registration Statement has been signed by the following persons in the capacities and on the date indicated.
Signature
Title
Date
/s/ Cameron Reynolds
Cameron Reynolds
President, Chief Executive Officer and Director
(Principal Executive Officer)
October 14, 2016
/s/ David Kratochvil
David Kratochvil
Chief Financial Officer and Treasurer
(Principal Financial and Accounting Officer)
October 14, 2016
/s/ Rodney Gerard Rootsaert
Rodney Gerard Rootsaert
Secretary
October 14, 2016
/s/ Dr. Martin Faulkes
Dr. Martin Faulkes
Director
October 14, 2016
/s/ Guy Innes
Guy Innes
Director
October 14, 2016
/s/ Dr. Alan Colman
Dr. Alan Colman
Director
October 14, 2016
/s/ Dr. Habib Skaff
Dr. Habib Skaff
Director
October 14, 2016
/s/ Dr. Edward Futcher
Dr. Edward Futcher
Director
October 14, 2016
4
EXHIBIT INDEX
Incorporated by Reference
Exhibit Number
Exhibit Description
Form
File No.
Exhibit
Filing Date
Filed Herewith
4.1
Second Amended and Restated Certificate of Incorporation.
8-K
001-36833
3.1
10/11/16
4.2
Amended and Restated Bylaws.
S-8
333-208512
4.2
12/11/15
5.1
Opinion of Stradling Yocca Carlson & Rauth, a Professional Corporation.
X
10.1
2015 Stock Incentive Plan, as amended.
X
10.2
Form of Notice of Stock Option Grant and Stock Option Agreement under the 2015 Stock Incentive Plan.
X
10.3
Form of Notice of Restricted Stock Award and Restricted Stock Agreement under the 2015 Stock Incentive Plan.
X
10.4
Form of Notice of Stock Bonus Award and Stock Bonus Award Agreement under the 2015 Stock Incentive Plan.
X
10.5
Form of Notice of Stock Appreciation Right Award and Stock Appreciation Right Award Agreement under the 2015 Stock Incentive Plan.
X
10.6
Form of Notice of Restricted Stock Unit Award and Restricted Stock Unit Agreement under the 2015 Stock Incentive Plan.
X
10.7
Form of Notice of Performance Shares Award and Performance Shares Agreement under the 2015 Stock Incentive Plan.
X
23.1
Consent of Stradling Yocca Carlson & Rauth, a Professional Corporation (contained in Exhibit 5.1).
X
23.2
Consent of Independent Registered Public Accounting Firm (Sadler, Gibb and Associates, LLC).
X
24.1
Power of Attorney (contained on signature page).
X
1