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   <TITLE>SIAL- Share Option Plan of 2000 Form S-8</TITLE>
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<center><font size=-1>As Filed with the Securities and Exchange Commission
on November 13, 2000</font></center>

<div align=right><font size=-1>Registration No. ___________</font></div>

<center><b><u><font size=-1>____________________________________________________________________________________________</font></u></b>
<p><b><font size=-1>SECURITIES AND EXCHANGE COMMISSION</font></b>
<p><b><font size=-1>Washington, D.C. 20549</font></b>
<p><b><font size=-1>___________________________________________________</font></b>
<p><b><font size=-1>FORM S-8</font></b>
<p><b><font size=-1>REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF
1933</font></b>
<p><b><font size=-1>__________________________________________________</font></b>
<p><b><font size=-1>SIGMA-ALDRICH CORPORATION</font></b>
<p><font size=-2>(Exact Name Of Registrant As Specified In Its Charter)</font></center>

<center><table CELLPADDING=6 WIDTH="688" >
<tr>
<td VALIGN=TOP WIDTH="22%">
<center><b><u><font size=-1>Delaware</font></u></b></center>
</td>

<td VALIGN=TOP WIDTH="48%">&nbsp;</td>

<td VALIGN=TOP WIDTH="30%">
<center><b><u><font size=-1>43-1050617</font></u></b></center>
</td>
</tr>

<tr>
<td VALIGN=TOP WIDTH="22%">
<center><font size=-2>(State or other jurisdiction of incorporation or
organization)</font></center>
</td>

<td VALIGN=TOP WIDTH="48%">
<dir>
<center><b><font size=-1>3050 Spruce Street</font></b>
<br><b><font size=-1>St. Louis, Missouri 63103</font></b>
<br><b><font size=-1>(314) 771-5765</font></b></center>
</dir>
</td>

<td VALIGN=TOP WIDTH="30%">
<center><font size=-2>(I.R.S. Employer&nbsp;</font>
<p><font size=-2>Identification No.)</font></center>
</td>
</tr>

<tr>
<td VALIGN=TOP WIDTH="22%">&nbsp;</td>

<td VALIGN=TOP WIDTH="48%">
<dir>
<center><font size=-2>(Address, including zip code, and telephone number,</font></center>
</dir>
</td>

<td VALIGN=TOP WIDTH="30%">&nbsp;</td>
</tr>

<tr>
<td VALIGN=TOP WIDTH="22%">&nbsp;</td>

<td VALIGN=TOP WIDTH="48%">
<dir>
<center><font size=-2>including area code, of registrant's principal executive
office)&nbsp;</font></center>
</dir>
</td>

<td VALIGN=TOP WIDTH="30%">&nbsp;</td>
</tr>

<tr>
<td VALIGN=TOP WIDTH="22%">&nbsp;</td>

<td VALIGN=TOP WIDTH="48%">&nbsp;</td>

<td VALIGN=TOP WIDTH="30%">&nbsp;</td>
</tr>
</TABLE></center>

<center>
<p>SIGMA-ALDRICH CORPORATION SHARE OPTION PLAN OF 2000
<p><font size=-1>(Full Title of the Plan)</font>
<p><font size=+0>KIRK A. RICHTER</font>
<br><font size=+0>Treasurer</font>
<br><font size=+0>Sigma-Aldrich Corporation</font>
<br><font size=+0>3050 Spruce Street</font>
<br><font size=+0>St. Louis, MO 63103</font>
<br><font size=+0>(314) 771-5765</font>
<br><font size=-1>(Name, Address, including Zip Code and Telephone Number,</font>
<br><font size=-1>including Area Code, of Agent For Service)</font>
<p><font size=+0>Copies of all correspondence to:</font>
<br><font size=+0>R. Randall Wang, Esq.</font>
<br><font size=+0>Bryan Cave </font><font size=-2>LLP</font>
<br><font size=+0>211 N. Broadway, Suite 3600</font>
<br><font size=+0>St. Louis, MO 63102</font>
<br><font size=+0>(314) 259-2000</font>
<p><font size=-1>CALCULATION OF REGISTRATION FEE</font></center>

<p><br>
<center><table BORDER CELLPADDING=8 WIDTH="645" >
<tr>
<td VALIGN=TOP WIDTH="31%">
<center><font size=-2>Title of securities to be registered</font></center>
</td>

<td VALIGN=TOP WIDTH="16%">
<center><font size=-2>Amount to be registered</font></center>
</td>

<td VALIGN=TOP WIDTH="19%">
<center><font size=-2>Proposed maximum offering price per share<sup>(3)</sup></font></center>
</td>

<td VALIGN=TOP WIDTH="20%">
<center><font size=-2>Proposed maximum aggregate offering price<sup>(3)</sup></font></center>
</td>

<td VALIGN=TOP WIDTH="15%">
<center><font size=-2>Amount of registration fee</font></center>
</td>
</tr>

<tr>
<td VALIGN=TOP WIDTH="31%">
<center><font size=-1>Common Stock, $1.00 par value per share, and associated
common stock purchase rights (2)</font></center>
</td>

<td VALIGN=TOP WIDTH="16%">
<center><font size=-1>4,500,000 shares</font><sup><font size=-2>(1)</font></sup></center>
</td>

<td VALIGN=TOP WIDTH="19%">
<center><font size=-1>36.40</font></center>
</td>

<td VALIGN=TOP WIDTH="20%">
<center><font size=-1>$163,814,047.88</font></center>
</td>

<td VALIGN=TOP WIDTH="15%">
<center><font size=-1>$43,246.91</font></center>
</td>
</tr>
</TABLE></center>

<dir>
<dir>&nbsp;
<br><font size=-2>(1)The registration statement also includes an indeterminable
number of additional shares that may become issuable pursuant to antidilution
provisions. In addition, pursuant to Rule 416(c) under the Securities Act
of 1933, this registration statement also covers an indeterminate amount
of interests to be offered or sold pursuant to the employee benefit plan(s)
described herein.</font>
<p><font size=-2>(2) Each share of common stock also represents one common
stock purchase right. Common stock purchase rights cannot trade separately
from the underlying common stock and, therefore, do not carry a separate
price or necessitate an additional fee.</font>
<p><font size=-2>(3) Estimated solely for the purpose of calculating the
registration fee pursuant to Rule 457(c) and Rule 457(h). The proposed
maximum offering price per share represents the weighted average exercise
price of currently outstanding options under the Share Option Plan of 2000
and the average of the high and low prices of the Common Stock on November
10, 2000, as reported by The Nasdaq National Market, for the shares reserved
for issuance under the remaining options under such plan.</font>
<p><font size=-2>(4) Omitted pursuant to Rule 457(o) under the Securities
Act of 1933.</font></dir>
</dir>

<center><b><font size=-1>PART II</font></b>
<p><font size=-1>INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</font></center>

<p><b><font size=-1>Item 3. Incorporation of Documents by Reference.</font></b>
<p><font size=-1>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The following
documents, which are on file with the Securities and Exchange Commission
under File No. 0-8135 are incorporated herein by reference:</font>
<dir>
<dir><font size=-1>(a) Sigma-Aldrich Corporation's ("Sigma-Aldrich" or
the "Company") Annual Report on Form 10-K for the year ended December 31,
1999 (File No. 0-8135);</font>
<p><font size=-1>(b) The Company's Quarterly Report on Form 10-Q for the
three months ended March 31, 2000, as amended on Form 10-Q/A filed on June
2, 2000, and June 30, 2000;</font>
<p><font size=-1>(c) The Company's Current Report on Form 8-K dated May
15, 2000 (filed May 15, 2000) and August 9, 2000 (filed August 11, 2000);</font>
<p><font size=-1>(d) The description of the Company's Common Stock contained
in the Company's registration statement on Form S-14 under the Securities
Act of 1933, dated May 16, 1975 (File No. 2-53698), as amended by the description
contained in the Company's proxy statements dated May 29, 1984 under the
caption "Proposal to Amend Certificate of Incorporation," dated March 29,
1991 under the caption "Proposal to Amend Certificate of Incorporation
to Increase Authorized Common Stock" and dated March 29, 1996 under the
caption "Proposal to Amend Certificate of Incorporation to Increase Number
of Shares of Authorized Common Stock"; and</font>
<p><font size=-1>(e) The description of the Company's Common Stock Purchase
Rights contained in the Company's registration statement on Form 8-A dated
August 9, 2000 (filed August 10, 2000).</font></dir>
</dir>
<font size=-1>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; All documents
subsequently filed by Sigma-Aldrich pursuant to Sections 13(a), 13(c),
14, and 15(d) of the Securities Exchange Act of 1934, prior to the filing
of a post-effective amendment which indicates that all securities offered
have been sold or which deregisters all securities then remaining unsold,
shall be deemed to be incorporated by reference and to be a part hereof
from the date of filing of such documents. Any statement contained herein
or in a document incorporated, or deemed to be incorporated, by reference
herein, shall be deemed to be modified or superseded for purposes hereof
to the extent that a statement contained herein or in any other subsequently
filed document which also is or is deemed to be incorporated by reference
herein modifies or supersedes such statement. Any such statement so modified
or superseded shall not be deemed, except as so modified or superseded,
to constitute a part hereof.</font>
<p><b><font size=-1>Item 4. Description of Securities.</font></b>
<p><font size=-1>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The authorized
capital stock of the Company consists of 200,000,000 shares of Common Stock,
$1.00 par value per share. Dividends may be paid on the Common Stock as
and when declared by the Board of Directors out of any funds legally available
therefor. The holders of Common Stock are entitled to one vote per share
in the election of directors and in respect of other matters submitted
to shareholders for a vote. Upon liquidation, the holders of the Common
Stock are entitled to receive all assets of the Company available for distribution
to stockholders pro rata in accordance with their holdings.</font>
<p><font size=-1>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The Company's
Certificate of Incorporation as amended requires that a merger or consolidation
of the Company with another corporation or which involves a subsidiary
of the Company when shares of the Company in excess of 35 percent of the
outstanding shares are issued; a sale of assets having an aggregate book
value of 20 percent of the Company's total assets; the adoption of a plan
of liquidation or dissolution; and certain related transactions must be
approved by the affirmative vote of two-thirds of the shares of voting
stock.</font>
<p><font size=-1>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The Common
Stock has no preemptive or conversion rights, redemption provisions or
sinking fund provisions. The outstanding Common Stock, including the Common
Stock offered hereby, is fully-paid and nonassessable.</font>
<p><font size=-1>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Pursuant to
the Rights Agreement between the Company and Computershare Investor Services,
LLC, as Rights Agent, dated August 8, 2000, the Board of Directors declared
a dividend of one common share purchase right for each outstanding share
of common stock held by stockholders on August 22, 2000. Each right entitles
the holder to purchase one share of the Company's Common Stock for $150.00,
subject to adjustment. A description of the rights is contained in the
Company's Registration Statement on Form 8-A dated August 9, 2000 (filed
August 10, 2000), which is incorporated herein by reference.</font>
<p><font size=-1>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The By-Laws
contain provisions requiring advance notice of nominations of directors
or of the proposal of other business to be conducted at meetings of stockholders.
Special meetings of stockholders, unless otherwise prescribed by statute,
may be called by the Chairman of the Board of Directors, the President
or the Board of Directors, or by the person designated in the written request
of holders of not less than a majority in amount of all shares of the Company
entitled to vote at the meeting (subject to any requirements or limitations
imposed by the Certificate of Incorporation, as amended, by the amended
By-Laws, or by law) which request must describe the purpose or purposes
for which the meeting is to be held.</font>
<p><b><font size=-1>Item 5. Interests of Named Experts and Counsel.</font></b>
<p><font size=-1>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Not applicable.</font>
<p><b><font size=-1>Item 6. Indemnification of Directors and Officers.</font></b>
<p><font size=-1>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Section 145(a)
of the Delaware General Corporation Law provides that a corporation may
indemnify any director, officer, employee or agent of the corporation in
any action, other than an action by or in the right of the corporation,
if such person acted in good faith and in a manner he reasonably believed
to be in or not opposed to the best interests of the corporation and, with
respect to any criminal action, had no reasonable cause to believe his
conduct was unlawful. Section 145(b) provides that the corporation may
indemnify any such person in an action by or in the right of the corporation
if he acted in good faith and in a manner he reasonably believed to be
in or not opposed to the best interests of the corporation, except that
such person may not be indemnified in respect of any matter in which he
has been judged liable to the corporation, unless authorized by the court.
Section 145(c) provides that the corporation shall indemnify any such person
against expenses actually and reasonably incurred in defense of any action
if he has been successful in the defense of such action and if such action
is one for which the corporation may indemnify such person under Section
145(a) or (b).</font>
<p><font size=-1>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The Company's
By-Laws provide that it shall indemnify and, in the Company's discretion,
may obtain insurance for the benefit of its officers and directors, to
the extent permitted by applicable Delaware law.</font>
<p><font size=-1>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The Company's
Certificate of Incorporation eliminates the personal liability of directors
to the Company or its shareholders for monetary damages for breach of fiduciary
duty as a director, except (i) for breaches of the duty of loyalty to the
Company or its shareholders, (ii) for acts or omissions not in good faith
or involving intentional misconduct or knowing violation of law, (iii)
for the payment of unlawful dividends or unlawful stock repurchases or
redemptions, or (iv) for transactions in which the director received an
improper personal benefit.</font>
<p><b><font size=-1>Item 7. Exemption from Registration Claimed.</font></b>
<p><font size=-1>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Not applicable.</font>
<p><b><font size=-1>Item 8. Exhibits.</font></b>
<p><font size=-1>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; See Exhibit
Index.</font>
<p><b><font size=-1>Item 9. Undertakings.</font></b>
<dir>
<dir><font size=-1>&nbsp;&nbsp;&nbsp; (a) The undersigned registrant hereby
undertakes:</font>
<p><font size=-1>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
(1) To file, during any period in which offers or sales are being made,
a post-effective amendment to this registration statement:</font>
<br>&nbsp;
<dir>
<dir><font size=-1>(i) To include any prospectus required by Section 10(a)(3)
of the Securities Act of 1933;</font>
<p><font size=-1>(ii) To reflect in the prospectus any facts or events
arising after the effective date of the registration statement (or the
most recent post-effective amendment thereof) which, individually or in
the aggregate, represent a fundamental change in the information set forth
in the registration statement. Notwithstanding the foregoing, any increase
or decrease in volume of securities offered (if the total dollar value
of securities offered would not exceed that which was registered) and any
deviation from the low or high end of the estimated maximum offering range
may be reflected in the form of prospectus filed with the Commission pursuant
to Rule 424(b) if, in the aggregate, the changes in volume and price represent
no more than a 20 percent change in the maximum aggregate offering price
set forth in the "Calculation of Registration Fee" table in the effective
registration statement;</font>
<p><font size=-1>(iii) To include any material information with respect
to the plan of distribution not previously disclosed in the registration
statement or any material change to such information in the registration
statement;</font>
<br>&nbsp;</dir>
</dir>
<font size=-1>provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii)
do not apply if the registration statement is on Form S-3, Form S-8, or
Form F-3, and the information required to be included in a post-effective
amendment by those paragraphs is contained in periodic reports filed with
or furnished to the Commission by the Registrant pursuant to Section 13
or Section 15(d) of the Securities Exchange Act of 1934 that are incorporated
by reference in the registration statement.</font>
<p><font size=-1>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
(2) That, for the purpose of determining any liability under the Securities
Act of 1933, each such post-effective amendment shall be deemed to be a
new registration statement relating to the securities offered therein,
and the offering of such securities at that time shall be deemed to be
the initial bona fide offering thereof.</font>
<p><font size=-1>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
(3) To remove from registration by means of a post-effective amendment
any of the securities being registered which remain unsold at the termination
of the offering.</font>
<p><font size=-1>&nbsp;&nbsp;&nbsp; (b) The undersigned Registrant hereby
undertakes that, for purposes of determining any liability under the Securities
Act of 1933, each filing of the Registrant's annual report pursuant to
Section 13(a) or 15(d) of the Securities Exchange Act of 1934 (and, where
applicable, each filing of an employee benefit plan's annual report pursuant
to Section 15(d) of the Securities Exchange Act of 1934) that is incorporated
by reference in the registration statement shall be deemed to be a new
registration statement relating to the securities offered therein, and
the offering of such securities at that time shall be deemed to be the
initial bona fide offering thereof.</font>
<p><font size=-1>&nbsp;&nbsp;&nbsp; (c) Insofar as indemnification for
liabilities arising under the Securities Act of 1933 may be permitted to
directors, officers, and controlling persons of the Registrant pursuant
to the foregoing provisions, or otherwise, the Registrant has been advised
that in the opinion of the Securities and Exchange Commission such indemnification
is against public policy as expressed in the Act and is, therefore, unenforceable.
In the event that a claim for indemnification against such liabilities
(other than the payment by the Registrant of expenses incurred or paid
by a director, officer, or controlling person of the Registrant in the
successful defense of any action, suit, or proceeding) is asserted by such
director, officer, or controlling person in connection with the securities
being registered, the Registrant will, unless in the opinion of its counsel
the matter has been settled by controlling precedent, submit to a court
of appropriate jurisdiction the question whether such indemnification by
it is against public policy as expressed in the Act and will be governed
by the final adjudication of such issue.</font>
<br>&nbsp;
<br>&nbsp;
<br>
<br>
<center>
<p><b><font size=-1>SIGNATURES</font></b></center>
</dir>
</dir>
<font size=-1>Pursuant to the requirements of the Securities Act of 1933,
the Registrant certifies that it has reasonable grounds to believe that
it meets all of the requirements for filing on Form S-8 and has duly caused
this registration statement to be signed on its behalf by the undersigned,
thereunto duly authorized in the City of St. Louis, State of Missouri on
November 13, 2000.</font>
<p><font size=-1>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
SIGMA-ALDRICH CORPORATION</font><font size=-1></font>
<p><font size=-1>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
By: <u>/s/ Kirk A. Richter</u></font>
<br><font size=-1>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
Kirk A. Richter, Treasurer</font>
<br><font size=-1></font>&nbsp;<font size=-1></font>
<center>
<p><b><font size=-1>POWER OF ATTORNEY</font></b></center>

<p><font size=-1>Each person whose signature appears below constitutes
and appoints Karen J. Miller, Michael R. Hogan and Kirk A. Richter, and
either of them, his or her true and lawful attorneys-in-fact and agents,
with full power of substitution and resubstitution, for him or her and
in his or her name, place and stead, in any and all capacities, to sign
any or all amendments to this registration statement and to file the same,
with all exhibits thereto and all other documents in connection therewith
with the Securities and Exchange Commission, granting unto said attorneys-in-fact
and agents full power and authority to do and perform each and every act
and thing requisite and necessary to be done in and about the premises,
as fully as he or she might or could do in person, hereby ratifying and
confirming all that said attorneys-in-fact and agents may lawfully do or
cause to be done by virtue hereof.</font>
<p><font size=-1>Pursuant to the requirements of the Securities Act of
1933, this registration statement has been signed by the following persons
in the capacities and on the date indicated.</font>
<table CELLSPACING=3 CELLPADDING=3 WIDTH="72%" >
<tr>
<td><u><font size=-1>Signature</font></u></td>

<td>
<center><u><font size=-1>Title</font></u></center>
</td>

<td></td>
</tr>

<tr>
<td></td>

<td></td>

<td></td>
</tr>

<tr>
<td><u><font size=-1>/s/ Carl T. Cori</font></u></td>

<td><font size=-1>Director and Chairman of the Board</font></td>

<td>
<center><u><font size=-1>November 13, 2000</font></u></center>
</td>
</tr>

<tr>
<td><font size=-1>Carl T. Cori</font></td>

<td></td>

<td>
<center><font size=-1>Date</font></center>
</td>
</tr>

<tr>
<td></td>

<td></td>

<td></td>
</tr>

<tr>
<td><u><font size=-1>/s/ David R. Harvey</font></u></td>

<td><font size=-1>Director, President and</font></td>

<td>
<center><u><font size=-1>November 13, 2000</font></u></center>
</td>
</tr>

<tr>
<td><font size=-1>David R. Harvey</font></td>

<td><font size=-1>Chief Executive Officer</font></td>

<td>
<center><font size=-1>Date</font></center>
</td>
</tr>

<tr>
<td></td>

<td></td>

<td></td>
</tr>

<tr>
<td><u><font size=-1>/s/ Michael R. Hogan&nbsp;</font></u></td>

<td><font size=-1>Chief Financial Officer</font></td>

<td>
<center><u><font size=-1>November 13, 2000</font></u></center>
</td>
</tr>

<tr>
<td><font size=-1>Michael R. Hogan</font></td>

<td></td>

<td>
<center><font size=-1>Date</font></center>
</td>
</tr>

<tr>
<td></td>

<td></td>

<td></td>
</tr>

<tr>
<td><u><font size=-1>/s/ Karen J. Miller</font></u></td>

<td><font size=-1>Controller (also functions as Chief</font></td>

<td>
<center><u><font size=-1>November 13, 2000</font></u></center>
</td>
</tr>

<tr>
<td><font size=-1>Karen J. Miller</font></td>

<td><font size=-1>Accounting Officer)</font></td>

<td>
<center><font size=-1>Date</font></center>
</td>
</tr>

<tr>
<td></td>

<td></td>

<td></td>
</tr>

<tr>
<td><u><font size=-1>/s/ Nina V. Fedoroff&nbsp;</font></u></td>

<td><font size=-1>Director</font></td>

<td>
<center><u><font size=-1>November 13, 2000</font></u></center>
</td>
</tr>

<tr>
<td><font size=-1>Nina V. Fedoroff</font></td>

<td></td>

<td>
<center><font size=-1>Date</font></center>
</td>
</tr>

<tr>
<td></td>

<td></td>

<td></td>
</tr>

<tr>
<td><u><font size=-1>/s/ David M. Kipnis&nbsp;</font></u></td>

<td><font size=-1>Director</font></td>

<td>
<center><u><font size=-1>November 13, 2000</font></u></center>
</td>
</tr>

<tr>
<td><font size=-1>David M. Kipnis</font></td>

<td></td>

<td>
<center><font size=-1>Date</font></center>
</td>
</tr>

<tr>
<td></td>

<td></td>

<td></td>
</tr>

<tr>
<td><u><font size=-1>/s/ Andrew E. Newman</font></u></td>

<td><font size=-1>Director</font></td>

<td>
<center><u><font size=-1>November 13, 2000</font></u></center>
</td>
</tr>

<tr>
<td><font size=-1>Andrew E. Newman</font></td>

<td></td>

<td>
<center><font size=-1>Date</font></center>
</td>
</tr>

<tr>
<td></td>

<td></td>

<td></td>
</tr>

<tr>
<td><u><font size=-1>/s/ William C. O'Neil, Jr.</font></u></td>

<td><font size=-1>Director</font></td>

<td>
<center><u><font size=-1>November 13, 2000</font></u></center>
</td>
</tr>

<tr>
<td><font size=-1>William C. O'Neil, Jr.</font></td>

<td></td>

<td>
<center><font size=-1>Date</font></center>
</td>
</tr>

<tr>
<td></td>

<td></td>

<td></td>
</tr>

<tr>
<td><u><font size=-1>/s/ Jerome W. Sandweiss</font></u></td>

<td><font size=-1>Director</font></td>

<td>
<center><u><font size=-1>November 13, 2000</font></u></center>
</td>
</tr>

<tr>
<td><font size=-1>Jerome W. Sandweiss</font></td>

<td></td>

<td>
<center><font size=-1>Date</font></center>
</td>
</tr>

<tr>
<td></td>

<td></td>

<td></td>
</tr>

<tr>
<td><u><font size=-1>/s/ D. Dean Spatz</font></u></td>

<td><font size=-1>Director</font></td>

<td>
<center><u><font size=-1>November 13, 2000</font></u></center>
</td>
</tr>

<tr>
<td><font size=-1>D. Dean Spatz</font></td>

<td></td>

<td>
<center><font size=-1>Date</font></center>
</td>
</tr>

<tr>
<td></td>

<td></td>

<td></td>
</tr>

<tr>
<td><u><font size=-1>/s/ Thomas N. Urban&nbsp;</font></u></td>

<td><font size=-1>Director</font></td>

<td>
<center><u><font size=-1>November 13, 2000</font></u></center>
</td>
</tr>

<tr>
<td><font size=-1>Thomas N. Urban</font></td>

<td></td>

<td>
<center><font size=-1>Date</font></center>
</td>
</tr>
</TABLE>

<br>&nbsp;
<p><b><u><font size=-1>EXHIBIT INDEX</font></u></b>
<br>&nbsp;
<table CELLSPACING=3 CELLPADDING=3 WIDTH="72%" >
<tr>
<td><u><font size=-1>Exhibit Number</font></u></td>

<td><u><font size=-1>Description</font></u></td>
</tr>

<tr>
<td><font size=-1>4.1</font></td>

<td><font size=-1>Certificate of Incorporation, as amended (incorporated
by reference to Exhibit 3(a) of the Company's Quarterly Report on Form10-Q
for the quarter ended September 30, 1996, File No. 0-8135)</font></td>
</tr>

<tr>
<td></td>

<td></td>
</tr>

<tr>
<td><font size=-1>4.2</font></td>

<td><font size=-1>By-Laws, as amended (incorporated by reference to Exhibit3.1
of the Company's Current Report on Form 8-K filed on December 22, 1999,
File No. 0-8135)</font></td>
</tr>

<tr>
<td></td>

<td></td>
</tr>

<tr>
<td><font size=-1>4.3</font></td>

<td><font size=-1>Rights Agreement between Sigma-Aldrich Corporationand
Computershare Investor Services, LLC, as Rights Agent (incorporated byreference
to Exhibit 1 of the Company's Registration Statement on Form8-A dated August
9, 2000 (filed August 10, 2000, File No. 0-8135)</font></td>
</tr>

<tr>
<td></td>

<td></td>
</tr>

<tr>
<td><font size=-1>5.1</font></td>

<td><font size=-1>Opinion of Counsel</font></td>
</tr>

<tr>
<td></td>

<td></td>
</tr>

<tr>
<td><font size=-1>23.1</font></td>

<td><font size=-1>Consent of Counsel (included in Exhibit 5.1)</font></td>
</tr>

<tr>
<td></td>

<td></td>
</tr>

<tr>
<td><font size=-1>23.2</font></td>

<td><font size=-1>Consent of Arthur Andersen LLP</font></td>
</tr>

<tr>
<td></td>

<td></td>
</tr>

<tr>
<td><font size=-1>24.1</font></td>

<td><font size=-1>Power of Attorney (included on signature page)</font></td>
</tr>
</TABLE>

</body>
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{"company-data": {"conformed-name": "SIGMA ALDRICH CORP", "cik": "0000090185", "assigned-sic": "5160", "irs-number": "431050617", "state-of-incorporation": "DE", "fiscal-year-end": "1231"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-49912", "film-number": "767127"}, "business-address": {"street1": "3050 SPRUCE ST", "city": "ST LOUIS", "state": "MO", "zip": "63103", "phone": "3147715765"}, "mail-address": {"street1": "3050 SPRUCE STREET", "city": "ST LOUIS", "state": "MO", "zip": "63103"}, "former-company": [{"former-conformed-name": "SIGMA INTERNATIONAL LTD", "date-changed": "19750925"}, {"former-conformed-name": "ALDRICH CHEMICAL CO INC", "date-changed": "19750908"}]}
SIAL- Share Option Plan of 2000 Form S-8
As Filed with the Securities and Exchange Commission
on November 13, 2000
Registration No. ___________
____________________________________________________________________________________________
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
___________________________________________________
FORM S-8
REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF
1933
__________________________________________________
SIGMA-ALDRICH CORPORATION
(Exact Name Of Registrant As Specified In Its Charter)
Delaware
43-1050617
(State or other jurisdiction of incorporation or
organization)
3050 Spruce Street
St. Louis, Missouri 63103
(314) 771-5765
(I.R.S. Employer
Identification No.)
(Address, including zip code, and telephone number,
including area code, of registrant's principal executive
office)
SIGMA-ALDRICH CORPORATION SHARE OPTION PLAN OF 2000
(Full Title of the Plan)
KIRK A. RICHTER
Treasurer
Sigma-Aldrich Corporation
3050 Spruce Street
St. Louis, MO 63103
(314) 771-5765
(Name, Address, including Zip Code and Telephone Number,
including Area Code, of Agent For Service)
Copies of all correspondence to:
R. Randall Wang, Esq.
Bryan Cave
LLP
211 N. Broadway, Suite 3600
St. Louis, MO 63102
(314) 259-2000
CALCULATION OF REGISTRATION FEE
Title of securities to be registered
Amount to be registered
Proposed maximum offering price per share
(3)
Proposed maximum aggregate offering price
(3)
Amount of registration fee
Common Stock, $1.00 par value per share, and associated
common stock purchase rights (2)
4,500,000 shares
(1)
36.40
$163,814,047.88
$43,246.91
(1)The registration statement also includes an indeterminable
number of additional shares that may become issuable pursuant to antidilution
provisions. In addition, pursuant to Rule 416(c) under the Securities Act
of 1933, this registration statement also covers an indeterminate amount
of interests to be offered or sold pursuant to the employee benefit plan(s)
described herein.
(2) Each share of common stock also represents one common
stock purchase right. Common stock purchase rights cannot trade separately
from the underlying common stock and, therefore, do not carry a separate
price or necessitate an additional fee.
(3) Estimated solely for the purpose of calculating the
registration fee pursuant to Rule 457(c) and Rule 457(h). The proposed
maximum offering price per share represents the weighted average exercise
price of currently outstanding options under the Share Option Plan of 2000
and the average of the high and low prices of the Common Stock on November
10, 2000, as reported by The Nasdaq National Market, for the shares reserved
for issuance under the remaining options under such plan.
(4) Omitted pursuant to Rule 457(o) under the Securities
Act of 1933.
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 3. Incorporation of Documents by Reference.
The following
documents, which are on file with the Securities and Exchange Commission
under File No. 0-8135 are incorporated herein by reference:
(a) Sigma-Aldrich Corporation's ("Sigma-Aldrich" or
the "Company") Annual Report on Form 10-K for the year ended December 31,
1999 (File No. 0-8135);
(b) The Company's Quarterly Report on Form 10-Q for the
three months ended March 31, 2000, as amended on Form 10-Q/A filed on June
2, 2000, and June 30, 2000;
(c) The Company's Current Report on Form 8-K dated May
15, 2000 (filed May 15, 2000) and August 9, 2000 (filed August 11, 2000);
(d) The description of the Company's Common Stock contained
in the Company's registration statement on Form S-14 under the Securities
Act of 1933, dated May 16, 1975 (File No. 2-53698), as amended by the description
contained in the Company's proxy statements dated May 29, 1984 under the
caption "Proposal to Amend Certificate of Incorporation," dated March 29,
1991 under the caption "Proposal to Amend Certificate of Incorporation
to Increase Authorized Common Stock" and dated March 29, 1996 under the
caption "Proposal to Amend Certificate of Incorporation to Increase Number
of Shares of Authorized Common Stock"; and
(e) The description of the Company's Common Stock Purchase
Rights contained in the Company's registration statement on Form 8-A dated
August 9, 2000 (filed August 10, 2000).
All documents
subsequently filed by Sigma-Aldrich pursuant to Sections 13(a), 13(c),
14, and 15(d) of the Securities Exchange Act of 1934, prior to the filing
of a post-effective amendment which indicates that all securities offered
have been sold or which deregisters all securities then remaining unsold,
shall be deemed to be incorporated by reference and to be a part hereof
from the date of filing of such documents. Any statement contained herein
or in a document incorporated, or deemed to be incorporated, by reference
herein, shall be deemed to be modified or superseded for purposes hereof
to the extent that a statement contained herein or in any other subsequently
filed document which also is or is deemed to be incorporated by reference
herein modifies or supersedes such statement. Any such statement so modified
or superseded shall not be deemed, except as so modified or superseded,
to constitute a part hereof.
Item 4. Description of Securities.
The authorized
capital stock of the Company consists of 200,000,000 shares of Common Stock,
$1.00 par value per share. Dividends may be paid on the Common Stock as
and when declared by the Board of Directors out of any funds legally available
therefor. The holders of Common Stock are entitled to one vote per share
in the election of directors and in respect of other matters submitted
to shareholders for a vote. Upon liquidation, the holders of the Common
Stock are entitled to receive all assets of the Company available for distribution
to stockholders pro rata in accordance with their holdings.
The Company's
Certificate of Incorporation as amended requires that a merger or consolidation
of the Company with another corporation or which involves a subsidiary
of the Company when shares of the Company in excess of 35 percent of the
outstanding shares are issued; a sale of assets having an aggregate book
value of 20 percent of the Company's total assets; the adoption of a plan
of liquidation or dissolution; and certain related transactions must be
approved by the affirmative vote of two-thirds of the shares of voting
stock.
The Common
Stock has no preemptive or conversion rights, redemption provisions or
sinking fund provisions. The outstanding Common Stock, including the Common
Stock offered hereby, is fully-paid and nonassessable.
Pursuant to
the Rights Agreement between the Company and Computershare Investor Services,
LLC, as Rights Agent, dated August 8, 2000, the Board of Directors declared
a dividend of one common share purchase right for each outstanding share
of common stock held by stockholders on August 22, 2000. Each right entitles
the holder to purchase one share of the Company's Common Stock for $150.00,
subject to adjustment. A description of the rights is contained in the
Company's Registration Statement on Form 8-A dated August 9, 2000 (filed
August 10, 2000), which is incorporated herein by reference.
The By-Laws
contain provisions requiring advance notice of nominations of directors
or of the proposal of other business to be conducted at meetings of stockholders.
Special meetings of stockholders, unless otherwise prescribed by statute,
may be called by the Chairman of the Board of Directors, the President
or the Board of Directors, or by the person designated in the written request
of holders of not less than a majority in amount of all shares of the Company
entitled to vote at the meeting (subject to any requirements or limitations
imposed by the Certificate of Incorporation, as amended, by the amended
By-Laws, or by law) which request must describe the purpose or purposes
for which the meeting is to be held.
Item 5. Interests of Named Experts and Counsel.
Not applicable.
Item 6. Indemnification of Directors and Officers.
Section 145(a)
of the Delaware General Corporation Law provides that a corporation may
indemnify any director, officer, employee or agent of the corporation in
any action, other than an action by or in the right of the corporation,
if such person acted in good faith and in a manner he reasonably believed
to be in or not opposed to the best interests of the corporation and, with
respect to any criminal action, had no reasonable cause to believe his
conduct was unlawful. Section 145(b) provides that the corporation may
indemnify any such person in an action by or in the right of the corporation
if he acted in good faith and in a manner he reasonably believed to be
in or not opposed to the best interests of the corporation, except that
such person may not be indemnified in respect of any matter in which he
has been judged liable to the corporation, unless authorized by the court.
Section 145(c) provides that the corporation shall indemnify any such person
against expenses actually and reasonably incurred in defense of any action
if he has been successful in the defense of such action and if such action
is one for which the corporation may indemnify such person under Section
145(a) or (b).
The Company's
By-Laws provide that it shall indemnify and, in the Company's discretion,
may obtain insurance for the benefit of its officers and directors, to
the extent permitted by applicable Delaware law.
The Company's
Certificate of Incorporation eliminates the personal liability of directors
to the Company or its shareholders for monetary damages for breach of fiduciary
duty as a director, except (i) for breaches of the duty of loyalty to the
Company or its shareholders, (ii) for acts or omissions not in good faith
or involving intentional misconduct or knowing violation of law, (iii)
for the payment of unlawful dividends or unlawful stock repurchases or
redemptions, or (iv) for transactions in which the director received an
improper personal benefit.
Item 7. Exemption from Registration Claimed.
Not applicable.
Item 8. Exhibits.
See Exhibit
Index.
Item 9. Undertakings.
(a) The undersigned registrant hereby
undertakes:
(1) To file, during any period in which offers or sales are being made,
a post-effective amendment to this registration statement:
(i) To include any prospectus required by Section 10(a)(3)
of the Securities Act of 1933;
(ii) To reflect in the prospectus any facts or events
arising after the effective date of the registration statement (or the
most recent post-effective amendment thereof) which, individually or in
the aggregate, represent a fundamental change in the information set forth
in the registration statement. Notwithstanding the foregoing, any increase
or decrease in volume of securities offered (if the total dollar value
of securities offered would not exceed that which was registered) and any
deviation from the low or high end of the estimated maximum offering range
may be reflected in the form of prospectus filed with the Commission pursuant
to Rule 424(b) if, in the aggregate, the changes in volume and price represent
no more than a 20 percent change in the maximum aggregate offering price
set forth in the "Calculation of Registration Fee" table in the effective
registration statement;
(iii) To include any material information with respect
to the plan of distribution not previously disclosed in the registration
statement or any material change to such information in the registration
statement;
provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii)
do not apply if the registration statement is on Form S-3, Form S-8, or
Form F-3, and the information required to be included in a post-effective
amendment by those paragraphs is contained in periodic reports filed with
or furnished to the Commission by the Registrant pursuant to Section 13
or Section 15(d) of the Securities Exchange Act of 1934 that are incorporated
by reference in the registration statement.
(2) That, for the purpose of determining any liability under the Securities
Act of 1933, each such post-effective amendment shall be deemed to be a
new registration statement relating to the securities offered therein,
and the offering of such securities at that time shall be deemed to be
the initial bona fide offering thereof.
(3) To remove from registration by means of a post-effective amendment
any of the securities being registered which remain unsold at the termination
of the offering.
(b) The undersigned Registrant hereby
undertakes that, for purposes of determining any liability under the Securities
Act of 1933, each filing of the Registrant's annual report pursuant to
Section 13(a) or 15(d) of the Securities Exchange Act of 1934 (and, where
applicable, each filing of an employee benefit plan's annual report pursuant
to Section 15(d) of the Securities Exchange Act of 1934) that is incorporated
by reference in the registration statement shall be deemed to be a new
registration statement relating to the securities offered therein, and
the offering of such securities at that time shall be deemed to be the
initial bona fide offering thereof.
(c) Insofar as indemnification for
liabilities arising under the Securities Act of 1933 may be permitted to
directors, officers, and controlling persons of the Registrant pursuant
to the foregoing provisions, or otherwise, the Registrant has been advised
that in the opinion of the Securities and Exchange Commission such indemnification
is against public policy as expressed in the Act and is, therefore, unenforceable.
In the event that a claim for indemnification against such liabilities
(other than the payment by the Registrant of expenses incurred or paid
by a director, officer, or controlling person of the Registrant in the
successful defense of any action, suit, or proceeding) is asserted by such
director, officer, or controlling person in connection with the securities
being registered, the Registrant will, unless in the opinion of its counsel
the matter has been settled by controlling precedent, submit to a court
of appropriate jurisdiction the question whether such indemnification by
it is against public policy as expressed in the Act and will be governed
by the final adjudication of such issue.
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933,
the Registrant certifies that it has reasonable grounds to believe that
it meets all of the requirements for filing on Form S-8 and has duly caused
this registration statement to be signed on its behalf by the undersigned,
thereunto duly authorized in the City of St. Louis, State of Missouri on
November 13, 2000.
SIGMA-ALDRICH CORPORATION
By:
/s/ Kirk A. Richter
Kirk A. Richter, Treasurer
POWER OF ATTORNEY
Each person whose signature appears below constitutes
and appoints Karen J. Miller, Michael R. Hogan and Kirk A. Richter, and
either of them, his or her true and lawful attorneys-in-fact and agents,
with full power of substitution and resubstitution, for him or her and
in his or her name, place and stead, in any and all capacities, to sign
any or all amendments to this registration statement and to file the same,
with all exhibits thereto and all other documents in connection therewith
with the Securities and Exchange Commission, granting unto said attorneys-in-fact
and agents full power and authority to do and perform each and every act
and thing requisite and necessary to be done in and about the premises,
as fully as he or she might or could do in person, hereby ratifying and
confirming all that said attorneys-in-fact and agents may lawfully do or
cause to be done by virtue hereof.
Pursuant to the requirements of the Securities Act of
1933, this registration statement has been signed by the following persons
in the capacities and on the date indicated.
Signature
Title
/s/ Carl T. Cori
Director and Chairman of the Board
November 13, 2000
Carl T. Cori
Date
/s/ David R. Harvey
Director, President and
November 13, 2000
David R. Harvey
Chief Executive Officer
Date
/s/ Michael R. Hogan
Chief Financial Officer
November 13, 2000
Michael R. Hogan
Date
/s/ Karen J. Miller
Controller (also functions as Chief
November 13, 2000
Karen J. Miller
Accounting Officer)
Date
/s/ Nina V. Fedoroff
Director
November 13, 2000
Nina V. Fedoroff
Date
/s/ David M. Kipnis
Director
November 13, 2000
David M. Kipnis
Date
/s/ Andrew E. Newman
Director
November 13, 2000
Andrew E. Newman
Date
/s/ William C. O'Neil, Jr.
Director
November 13, 2000
William C. O'Neil, Jr.
Date
/s/ Jerome W. Sandweiss
Director
November 13, 2000
Jerome W. Sandweiss
Date
/s/ D. Dean Spatz
Director
November 13, 2000
D. Dean Spatz
Date
/s/ Thomas N. Urban
Director
November 13, 2000
Thomas N. Urban
Date
EXHIBIT INDEX
Exhibit Number
Description
4.1
Certificate of Incorporation, as amended (incorporated
by reference to Exhibit 3(a) of the Company's Quarterly Report on Form10-Q
for the quarter ended September 30, 1996, File No. 0-8135)
4.2
By-Laws, as amended (incorporated by reference to Exhibit3.1
of the Company's Current Report on Form 8-K filed on December 22, 1999,
File No. 0-8135)
4.3
Rights Agreement between Sigma-Aldrich Corporationand
Computershare Investor Services, LLC, as Rights Agent (incorporated byreference
to Exhibit 1 of the Company's Registration Statement on Form8-A dated August
9, 2000 (filed August 10, 2000, File No. 0-8135)
5.1
Opinion of Counsel
23.1
Consent of Counsel (included in Exhibit 5.1)
23.2
Consent of Arthur Andersen LLP
24.1
Power of Attorney (included on signature page)