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<TITLE> S-8 </TITLE>
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<P ALIGN=CENTER><FONT SIZE=3>As filed with the Securities and Exchange Commission on May 9, 2002<BR>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
Registration No. 333-_____</FONT></P>
<HR SIZE=1 NOSHADE>

<P ALIGN=CENTER><FONT SIZE=5><B>SECURITIES AND EXCHANGE COMMISSION</B></FONT><BR>
<FONT SIZE=3><B>Washington, D.C. 20549</B></FONT></P>

<P ALIGN=CENTER><FONT SIZE=3><B>FORM S-8<BR>
REGISTRATION STATEMENT UNDER<BR>
THE SECURITIES ACT OF 1933</B></FONT></P>

<P ALIGN=CENTER><FONT SIZE=4><B>ALLIANCE PHARMACEUTICAL CORP.</B></FONT><BR>
<FONT SIZE=1>(Exact Name of Registrant as Specified in Its Charter)</FONT></P>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=50%>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<B>New York</B><BR>
(State or Other Jurisdiction of<BR>
Incorporation or Organization)</TD>
<TD WIDTH=50%><P ALIGN=CENTER><B>14-1644018</B><BR>
(IRS Employer<BR>
Identification Number)</P></TD>
</TR>
</TABLE>
<BR>

<P ALIGN=CENTER><FONT SIZE=3><B>3040 Science Park Road<BR>
San Diego, CA 92121<BR>
(858) 410-5200</B><BR>
(Address, including zip code, and telephone number, including area code, of
registrant's principal executive offices)<BR>
<B>2001 STOCK OPTION PLAN OF ALLIANCE PHARMACEUTICAL CORP.<BR>
EMPLOYEES' 401(k) PLAN OF ALLIANCE PHARMACEUTICAL CORP.</B><BR>
(Full title of the plan)<BR>
<B>DUANE J. ROTH</B><BR>
Chief Executive Officer<BR>
Alliance Pharmaceutical Corp.<BR>
3040 Science Park Road<BR>
San Diego, CA 92121<BR>
(858) 410-5200<BR>
(Name, address, including zip code, and telephone number, including area code, of agent
for service)<BR>
<B>Copy to:</B><BR>
Melvin Epstein, Esq.<BR>
Stroock &amp; Stroock &amp; Lavan LLP<BR>
180 Maiden Lane<BR>
New York, NY 10038<BR>
CALCULATION OF REGISTRATION FEE</FONT></P>

<TABLE WIDTH=100% CELLPADDING=1 CELLSPACING=1 BORDER=1>
<TR VALIGN=TOP>
<TD WIDTH=20% ALIGN=LEFT><BR>
Title of Shares to be<BR>
Registered</TD>
<TD WIDTH=20% ALIGN=LEFT><BR>
Amounts to be<BR>
Registered</TD>
<TD WIDTH=20% ALIGN=LEFT>
Proposed Maximum<BR>
Aggregate Price per<BR>
Unit(1)</TD>
<TD WIDTH=20% ALIGN=LEFT>
Proposed Maximum<BR>
Aggregate Offering<BR>
Price</TD>
<TD WIDTH=20% ALIGN=LEFT><BR>
<B>Amount of<BR>
Registration Fee</B></TD>
</TR>
</TABLE>

<TABLE WIDTH=100% CELLPADDING=1 CELLSPACING=1 BORDER=1>
<TR VALIGN=TOP>
<TD WIDTH=20% ALIGN=LEFT>
Common Stock,<BR>
$.01 par value.</TD>
<TD WIDTH=20% ALIGN=LEFT><BR>
661,176 shares (2)</TD>
<TD WIDTH=20% ALIGN=LEFT><BR>
$1.93 per share</TD>
<TD WIDTH=20% ALIGN=LEFT><BR>
$1,276,069.68</TD>
<TD WIDTH=20% ALIGN=LEFT><BR>
$117.40</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0>
<TR VALIGN=TOP>
<TD WIDTH=5%><FONT SIZE=3>(1)</FONT></TD>
<TD WIDTH=95%><FONT SIZE=3>Estimated solely for the purpose of calculating
the registration fee pursuant to Rule 457(c) and (h) of the Securities Act of
1933, as amended, based on the average of the high and low prices of the common
stock on the Nasdaq National Market on May 7, 2002.</FONT></TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0>
<TR VALIGN=TOP>
<TD WIDTH=5%><FONT SIZE=3>(2)</FONT></TD>
<TD WIDTH=95%><FONT SIZE=3>Represents 600,000 shares of common stock being registered for issuance under
the 2001 Stock Option Plan and 61,176 shares of common stock being registered
for issuance under the Employees' 401(k) Plan. Pursuant to Rule 416(a)
under the Securities Act of 1933, this Registration Statement also covers an
indeterminate number of shares of Common Stock which may be issued by reason of
stock splits, stock dividends or similar transactions.</FONT></TD>
</TR>
</TABLE>
<BR>

<HR SIZE=1 NOSHADE>
<PAGE>
<P ALIGN=LEFT><FONT SIZE=3><B>PART I</B></FONT></P>

<P ALIGN=CENTER><FONT SIZE=3><B>INFORMATION REQUIRED IN THE SECTION 10(A) PROSPECTUS</B></FONT></P>

<P><FONT SIZE=3>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The
documents containing the information specified in Part I of Form S-8 will be
sent or given to employees as specified by Rule 428(b)(1) promulgated under the
Securities Act of 1933, as amended (the "Securities Act"). Such documents need
not be filed with the Securities and Exchange Commission (the "Commission")
either as part of this Registration Statement or as prospectuses or prospectus
supplements pursuant to Rule 424 under the Securities Act. These documents and
the documents incorporated by reference in the Registration Statement pursuant
to Item 3 of Part II of this Form S-8, taken together, constitute a prospectus
that meets the requirements of Section 10(a) of the Securities Act. See Rule
428(a)(1) under the Securities Act.</FONT></P>

<P><FONT SIZE=3>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;This
Registration Statement covers 600,000 shares of Alliance Pharmaceutical Corp.
(the "Registrant") Common Stock, $.01 par value per share, to be issued pursuant
to the Registrant's 2001 Stock Option Plan and 61,176 shares of Common Stock,
$.01 par value per share, of the Registrant (plus any additional shares of
Common Stock that may be issued by reason of stock splits, stock dividends or
similar transactions) reserved for issuance under the Employees' 401(k) Plan of
the Registrant.</FONT></P>

<P ALIGN=LEFT><FONT SIZE=3><B>PART II</B></FONT></P>

<P ALIGN=CENTER><FONT SIZE=3><B>INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</B></FONT></P>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=7%><B>Item 3.</B></TD>
<TD WIDTH=93%><B><U>Incorporation of Documents by Reference</U>.</B></TD>
</TR>
</TABLE>
<BR>

<P><FONT SIZE=3>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The
following documents filed by the Registrant with the Securities and Exchange
Commission (the "Commission") are incorporated herein by reference:</FONT></P>

<P><FONT SIZE=3>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a)
The Registrant's Annual Report on Form 10-K for the fiscal year ended June 30,
2001;</FONT></P>

<P><FONT SIZE=3>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b)
The Registrant's Quarterly Report on Form 10-Q for the quarterly period ended
September 30, 2001 and December 31, 2001;</FONT></P>

<P><FONT SIZE=3>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c)
All other reports filed by the Registrant pursuant to Sections 13(a) and 15(d)
of the Exchange Act since the fiscal year covered by the annual report referred
to in (a) above; and </FONT></P>

<P><FONT SIZE=3>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(d)
The description of the Registrant's Common Stock, $.01 par value, which is
contained in the Registrant's Registration Statement on Form&#160;8-A, declared
effective October 25, 1984, filed with the Commission to register such Common
Stock pursuant to Section 12(b) of the Securities Exchange Act of 1934, as
amended (the "Exchange Act"). </FONT></P>

<P><FONT SIZE=3>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;All
documents subsequently filed by the Registrant pursuant to Sections 13(a),
13(c), 14 and 15(d) of the Exchange Act, prior to the filing of a post-effective
amendment which indicates that all securities offered hereby have been sold or
which deregisters all securities then remaining unsold, shall be deemed to be
incorporated by reference herein and to be a part hereof from the date of filing
of such documents.</FONT></P>

<P><FONT SIZE=3>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Any
statement contained herein or in a document incorporated or deemed to be
incorporated by reference herein shall be deemed to be modified or superseded
for purposes of this Registration Statement to the extent that a statement
contained herein or in any other subsequently filed document which also is or is
deemed to be incorporated by reference herein modifies or supersedes such
statement. Any statement so modified or superseded shall not be deemed, except
as so modified or superseded, to constitute a part of this Registration
Statement.</FONT></P>

<PAGE>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=7%><B>Item 4.</B></TD>
<TD WIDTH=93%><B><U>Description of Securities</U>.</B><BR>
<BR>
Not Applicable.</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=7%><B>Item 5.</B></TD>
<TD WIDTH=93%><B><U>Interests of Named Experts and Counsel</U>.</B><BR>
<BR>
Not applicable.</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=7%><B>Item 6.</B></TD>
<TD WIDTH=93%><B><U>Indemnification of Directors and Officers</U>.</B></TD>
</TR>
</TABLE>
<BR>

<P><FONT SIZE=3>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The
Certificate of Incorporation and By-laws of the Registrant provide for the
Registrant to indemnify its officers, directors and employees to the fullest
extent permitted by the New York Corporation Law against certain liabilities and
expenses.</FONT></P>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=7%><B>Item 7.</B></TD>
<TD WIDTH=93%><B><U>Exemption From Registration Claimed</U>.</B><BR>
<BR>
Not applicable.</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=7%><B>Item 8.</B></TD>
<TD WIDTH=93%><B><U>Exhibits</U>.</B></TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=7%>&nbsp;&nbsp;</TD>
<TD WIDTH=13%>Exhibit<BR>
<U>Number</U></TD>
<TD WIDTH=80%><U>Description</U></TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=7%>&nbsp;&nbsp;</TD>
<TD WIDTH=13%>4.1</TD>
<TD WIDTH=80%>2001 Stock Option Plan (incorporated by reference to Exhibit
10(e) of the Registrant's Form 10-Q dated March 31, 2001).</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=7%>&nbsp;&nbsp;</TD>
<TD WIDTH=13%>4.2</TD>
<TD WIDTH=80%>Form of Common Stock Certificate (incorporated by reference to Exhibit 4 of the
Registrant's Form S-2 dated April 19, 1989).</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=7%>&nbsp;&nbsp;</TD>
<TD WIDTH=13%>5</TD>
<TD WIDTH=80%>Opinion of Stroock &amp; Stroock &amp; Lavan LLP.</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=7%>&nbsp;&nbsp;</TD>
<TD WIDTH=13%>23.1</TD>
<TD WIDTH=80%>Consent of Stroock &amp; Stroock &amp; Lavan LLP (included in Exhibit 5 hereto).</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=7%>&nbsp;&nbsp;</TD>
<TD WIDTH=13%>23.2</TD>
<TD WIDTH=80%>Consent of Ernst &amp; Young LLP, Independent Auditors.</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=7%>&nbsp;&nbsp;</TD>
<TD WIDTH=13%>24</TD>
<TD WIDTH=80%>Power of Attorney (included as part of the signature page of this Registration Statement).</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=7%><B>Item 9.</B></TD>
<TD WIDTH=93%><B><U>Undertakings</U>.</B><BR>
<BR>
The undersigned Registrant hereby undertakes:</TD>
</TR>
</TABLE>
<BR>


<P><FONT SIZE=3>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1)
To file, during any period in which offers or sales are being made, a
post-effective amendment to this Registration Statement:</FONT></P>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=5%></TD>
<TD WIDTH=95%>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(i) To
include any prospectus required by Section 10(a)(3) of the Securities Act of
1933;</TD>
</TR>
</TABLE>
<BR>


<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=5%></TD>
<TD WIDTH=95%>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(ii)
To reflect in the prospectus any facts or events arising after the effective
date of the Registration Statement (or the most recent post- effective amendment
thereof) which, individually or in the aggregate, represent a fundamental change
in the information set forth in the Registration Statement;</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=5%></TD>
<TD WIDTH=95%>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(iii)
To include any material information with respect to the plan of distribution not
previously disclosed in the Registration Statement or any material change to
such information in the Registration Statement; </TD>
</TR>
</TABLE>
<BR>


<P><FONT SIZE=3><I>provided, however</I>, that paragraphs (1)(i) and (1)(ii) do
not apply if the Registration Statement is on Form S-3 or Form S-8 and the
information required to be included in a post-effective amendment by those
paragraphs is contained in periodic reports filed with or furnished to the
Commission by the Registrant pursuant to Section 13 or 15(d) of the Securities
Exchange Act of 1934 that are incorporated by reference in the Registration
Statement. </FONT></P>

<P><FONT SIZE=3>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2)
That, for the purpose of determining any liability under the Securities Act of
1933, each such post-effective amendment shall be deemed to be a new
Registration Statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial
<I>bona fide</I> offering thereof. </FONT></P>

<P><FONT SIZE=3>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3)
To remove from registration by means of a post-effective amendment any of the
securities being registered which remain unsold at the termination of the
offering. </FONT></P>

<P><FONT SIZE=3>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(4)
If the Registrant is a foreign private issuer, to file a post-effective
amendment to the Registration Statement to include any financial statements
required by Rule 3-19 of Regulation S-X at the start of any delayed offering or
throughout a continuous offering. </FONT></P>

<P><FONT SIZE=3>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The
undersigned Registrant hereby undertakes that, for purposes of determining any
liability under the Securities Act of 1933, each filing of the Registrant's
annual report pursuant to Section 13(a) or 15(d) of the Securities Exchange Act
of 1934 (and, where applicable, each filing of an employee benefit plan's annual
report pursuant to Section 15(d) of the Securities Exchange Act of 1934) that is
incorporated by reference in the Registration Statement shall be deemed to be a
new Registration Statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.</FONT></P>

<P><FONT SIZE=3>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
Insofar as indemnification for liabilities arising under the Securities Act of
1933 may be permitted to directors, officers and controlling persons of the
Registrant pursuant to the foregoing provisions, or otherwise, the Registrant
has been advised that in the opinion of the Securities and Exchange Commission
such indemnification is against public policy as expressed in the Securities Act
of 1933 and is, therefore, unenforceable. In the event that a claim for
indemnification against such liabilities (other than the payment by the
Registrant of expenses incurred or paid by a director, officer or controlling
person of the Registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the Registrant will, unless in
the opinion of its counsel the matter has been settled by controlling precedent,
submit to a court of appropriate jurisdiction the question whether such
indemnification by it is against public policy as expressed in the Securities
Act of 1933 and will be governed by the final adjudication of such issue.</FONT></P>

<PAGE>

<P ALIGN=CENTER><FONT SIZE=3><B>SIGNATURES</B></FONT></P>

<P><FONT SIZE=3>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
Pursuant to the requirements of the Securities Act of 1933, the Registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of San Diego, State of California, on May 9, 2002.</FONT></P>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=50%>&nbsp;&nbsp;</TD>
<TD WIDTH=50%><B>ALLIANCE PHARMACEUTICAL CORP.</B><BR>
(Registrant)</TD>
</TR>
</TABLE>
<BR>
<BR>
<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=50%>Date: May 9, 2002</TD>
<TD WIDTH=50%>By: <U>&nbsp;/s/ Theodore D. Roth
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U><BR>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Theodore D. Roth<BR>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;President and Chief Operating Officer</TD>
</TR>
</TABLE>
<BR>

<P ALIGN=CENTER><FONT SIZE=3><B>POWER OF ATTORNEY</B></FONT></P>

<P><FONT SIZE=3>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;KNOW
ALL MEN BY THESE PRESENTS, that each person whose signature appears below
constitutes and appoints Duane J. Roth and Theodore D. Roth, or either of them,
his true and lawful attorney-in-fact and agent, with full power of substitution
and resubstitution, for him and in his name, place and stead, in any and all
capacities, to sign any and all amendments to this Registration Statement, and
to file the same, with all exhibits thereto, and other documents in connection
therewith, with the Securities and Exchange Commission, granting unto said
attorney-in-fact and agent full power and authority to do and perform each and
every act and thing requisite and necessary to be done in and about the
premises, as fully to all intents and purposes as he might or could do in
person, hereby ratifying and confirming all that said attorney-in-fact, agent,
or their substitutes may lawfully do or cause to be done by virtue
hereof.</FONT></P>

<P><FONT SIZE=3><B>Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed by the following persons in the
capacities and on the dates indicated.</B> </FONT></P>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=40%>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<U>Signature</U></TD>
<TD WIDTH=40%>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<U>Title</U></TD>
<TD WIDTH=20%><U>Date</U></TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=40%><U>&nbsp;/s/ Duane J. Roth
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U><BR>
Duane J. Roth</TD>
<TD WIDTH=40%>Chairman and Chief Executive Officer</TD>
<TD WIDTH=20%>May 9, 2002</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=40%><U>&nbsp;/s/ Theodore D. Roth
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U><BR>
Theodore D. Roth</TD>
<TD WIDTH=40%>Director, President and Chief<BR>
Operating Officer</TD>
<TD WIDTH=20%>May 9, 2002</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=40%><U>&nbsp;/s/ Tim T. Hart
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U><BR>
Tim T. Hart</TD>
<TD WIDTH=40%>Chief Financial Officer, Treasurer<BR>
and Chief Accounting Officer</TD>
<TD WIDTH=20%>May 9, 2002</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=40%><U>&nbsp;/s/ Pedro Cuatrecasas, M.D.
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U><BR>
Pedro Cuatrecasas, M.D.</TD>
<TD WIDTH=40%>Director</TD>
<TD WIDTH=20%>May 9, 2002</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=40%><U>&nbsp;/s/ Fred M. Hershenson, Ph.D.
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U><BR>
Fred M. Hershenson, Ph.D.</TD>
<TD WIDTH=40%>Director</TD>
<TD WIDTH=20%>May 9, 2002</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=40%><U>&nbsp;/s/ Carroll O. Johnson
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U><BR>
Carroll O. Johnson</TD>
<TD WIDTH=40%>Director</TD>
<TD WIDTH=20%>May 9, 2002</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=40%><U>&nbsp;/s/ Stephen M. McGrath
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U><BR>
Stephen M. McGrath</TD>
<TD WIDTH=40%>Director</TD>
<TD WIDTH=20%>May 9, 2002</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=40%><U>&nbsp;/s/ Donald E. O'Neill
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U><BR>
Donald E. O'Neill</TD>
<TD WIDTH=40%>Director</TD>
<TD WIDTH=20%>May 9, 2002</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=40%><U>&nbsp;/s/ Helen M. Ranney, M.D.
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U><BR>
Helen M. Ranney, M.D.</TD>
<TD WIDTH=40%>Director</TD>
<TD WIDTH=20%>May 9, 2002</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=40%><U>&nbsp;/s/ Jean G. Riess, Ph.D.
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U><BR>
Jean G. Riess, Ph.D.</TD>
<TD WIDTH=40%>Director</TD>
<TD WIDTH=20%>May 9, 2002</TD>
</TR>
</TABLE>
<BR>

<TABLE WIDTH=100% CELLPADDING=0 CELLSPACING=0 BORDER=0>
<TR VALIGN=TOP>
<TD WIDTH=40%><U>&nbsp;/s/ Thomas F. Zuck, M.D.
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U><BR>
Thomas F. Zuck, M.D.</TD>
<TD WIDTH=40%>Director</TD>
<TD WIDTH=20%>May 9, 2002</TD>
</TR>
</TABLE>
<BR>

</BODY>
</HTML>
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{"company-data": {"conformed-name": "ALLIANCE PHARMACEUTICAL CORP", "cik": "0000736994", "assigned-sic": "2835", "irs-number": "141644018", "state-of-incorporation": "NY", "fiscal-year-end": "0630"}, "filing-values": {"form-type": "S-8", "act": "33", "file-number": "333-87916", "film-number": "02639981"}, "business-address": {"street1": "6175 LUSK BLVD", "city": "SAN DIEGO", "state": "CA", "zip": "92121", "phone": "8584105200"}, "mail-address": {"street1": "617 LUSK BLVD", "city": "SAN DIEGO", "state": "CA", "zip": "92121"}, "former-company": [{"former-conformed-name": "OTISVILLE BIOTECH INC", "date-changed": "19861216"}, {"former-conformed-name": "OTISVILLE BIOPHARM INC", "date-changed": "19890310"}]}
S-8
As filed with the Securities and Exchange Commission on May 9, 2002
Registration No. 333-_____
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-8
REGISTRATION STATEMENT UNDER
THE SECURITIES ACT OF 1933
ALLIANCE PHARMACEUTICAL CORP.
(Exact Name of Registrant as Specified in Its Charter)
New York
(State or Other Jurisdiction of
Incorporation or Organization)
14-1644018
(IRS Employer
Identification Number)
3040 Science Park Road
San Diego, CA 92121
(858) 410-5200
(Address, including zip code, and telephone number, including area code, of
registrant's principal executive offices)
2001 STOCK OPTION PLAN OF ALLIANCE PHARMACEUTICAL CORP.
EMPLOYEES' 401(k) PLAN OF ALLIANCE PHARMACEUTICAL CORP.
(Full title of the plan)
DUANE J. ROTH
Chief Executive Officer
Alliance Pharmaceutical Corp.
3040 Science Park Road
San Diego, CA 92121
(858) 410-5200
(Name, address, including zip code, and telephone number, including area code, of agent
for service)
Copy to:
Melvin Epstein, Esq.
Stroock & Stroock & Lavan LLP
180 Maiden Lane
New York, NY 10038
CALCULATION OF REGISTRATION FEE
Title of Shares to be
Registered
Amounts to be
Registered
Proposed Maximum
Aggregate Price per
Unit(1)
Proposed Maximum
Aggregate Offering
Price
Amount of
Registration Fee
Common Stock,
$.01 par value.
661,176 shares (2)
$1.93 per share
$1,276,069.68
$117.40
(1)
Estimated solely for the purpose of calculating
the registration fee pursuant to Rule 457(c) and (h) of the Securities Act of
1933, as amended, based on the average of the high and low prices of the common
stock on the Nasdaq National Market on May 7, 2002.
(2)
Represents 600,000 shares of common stock being registered for issuance under
the 2001 Stock Option Plan and 61,176 shares of common stock being registered
for issuance under the Employees' 401(k) Plan. Pursuant to Rule 416(a)
under the Securities Act of 1933, this Registration Statement also covers an
indeterminate number of shares of Common Stock which may be issued by reason of
stock splits, stock dividends or similar transactions.
PART I
INFORMATION REQUIRED IN THE SECTION 10(A) PROSPECTUS
The
documents containing the information specified in Part I of Form S-8 will be
sent or given to employees as specified by Rule 428(b)(1) promulgated under the
Securities Act of 1933, as amended (the "Securities Act"). Such documents need
not be filed with the Securities and Exchange Commission (the "Commission")
either as part of this Registration Statement or as prospectuses or prospectus
supplements pursuant to Rule 424 under the Securities Act. These documents and
the documents incorporated by reference in the Registration Statement pursuant
to Item 3 of Part II of this Form S-8, taken together, constitute a prospectus
that meets the requirements of Section 10(a) of the Securities Act. See Rule
428(a)(1) under the Securities Act.
This
Registration Statement covers 600,000 shares of Alliance Pharmaceutical Corp.
(the "Registrant") Common Stock, $.01 par value per share, to be issued pursuant
to the Registrant's 2001 Stock Option Plan and 61,176 shares of Common Stock,
$.01 par value per share, of the Registrant (plus any additional shares of
Common Stock that may be issued by reason of stock splits, stock dividends or
similar transactions) reserved for issuance under the Employees' 401(k) Plan of
the Registrant.
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 3.
Incorporation of Documents by Reference
.
The
following documents filed by the Registrant with the Securities and Exchange
Commission (the "Commission") are incorporated herein by reference:
(a)
The Registrant's Annual Report on Form 10-K for the fiscal year ended June 30,
2001;
(b)
The Registrant's Quarterly Report on Form 10-Q for the quarterly period ended
September 30, 2001 and December 31, 2001;
(c)
All other reports filed by the Registrant pursuant to Sections 13(a) and 15(d)
of the Exchange Act since the fiscal year covered by the annual report referred
to in (a) above; and
(d)
The description of the Registrant's Common Stock, $.01 par value, which is
contained in the Registrant's Registration Statement on Form 8-A, declared
effective October 25, 1984, filed with the Commission to register such Common
Stock pursuant to Section 12(b) of the Securities Exchange Act of 1934, as
amended (the "Exchange Act").
All
documents subsequently filed by the Registrant pursuant to Sections 13(a),
13(c), 14 and 15(d) of the Exchange Act, prior to the filing of a post-effective
amendment which indicates that all securities offered hereby have been sold or
which deregisters all securities then remaining unsold, shall be deemed to be
incorporated by reference herein and to be a part hereof from the date of filing
of such documents.
Any
statement contained herein or in a document incorporated or deemed to be
incorporated by reference herein shall be deemed to be modified or superseded
for purposes of this Registration Statement to the extent that a statement
contained herein or in any other subsequently filed document which also is or is
deemed to be incorporated by reference herein modifies or supersedes such
statement. Any statement so modified or superseded shall not be deemed, except
as so modified or superseded, to constitute a part of this Registration
Statement.
Item 4.
Description of Securities
.
Not Applicable.
Item 5.
Interests of Named Experts and Counsel
.
Not applicable.
Item 6.
Indemnification of Directors and Officers
.
The
Certificate of Incorporation and By-laws of the Registrant provide for the
Registrant to indemnify its officers, directors and employees to the fullest
extent permitted by the New York Corporation Law against certain liabilities and
expenses.
Item 7.
Exemption From Registration Claimed
.
Not applicable.
Item 8.
Exhibits
.
Exhibit
Number
Description
4.1
2001 Stock Option Plan (incorporated by reference to Exhibit
10(e) of the Registrant's Form 10-Q dated March 31, 2001).
4.2
Form of Common Stock Certificate (incorporated by reference to Exhibit 4 of the
Registrant's Form S-2 dated April 19, 1989).
5
Opinion of Stroock & Stroock & Lavan LLP.
23.1
Consent of Stroock & Stroock & Lavan LLP (included in Exhibit 5 hereto).
23.2
Consent of Ernst & Young LLP, Independent Auditors.
24
Power of Attorney (included as part of the signature page of this Registration Statement).
Item 9.
Undertakings
.
The undersigned Registrant hereby undertakes:
(1)
To file, during any period in which offers or sales are being made, a
post-effective amendment to this Registration Statement:
(i) To
include any prospectus required by Section 10(a)(3) of the Securities Act of
1933;
(ii)
To reflect in the prospectus any facts or events arising after the effective
date of the Registration Statement (or the most recent post- effective amendment
thereof) which, individually or in the aggregate, represent a fundamental change
in the information set forth in the Registration Statement;
(iii)
To include any material information with respect to the plan of distribution not
previously disclosed in the Registration Statement or any material change to
such information in the Registration Statement;
provided, however
, that paragraphs (1)(i) and (1)(ii) do
not apply if the Registration Statement is on Form S-3 or Form S-8 and the
information required to be included in a post-effective amendment by those
paragraphs is contained in periodic reports filed with or furnished to the
Commission by the Registrant pursuant to Section 13 or 15(d) of the Securities
Exchange Act of 1934 that are incorporated by reference in the Registration
Statement.
(2)
That, for the purpose of determining any liability under the Securities Act of
1933, each such post-effective amendment shall be deemed to be a new
Registration Statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial
bona fide
offering thereof.
(3)
To remove from registration by means of a post-effective amendment any of the
securities being registered which remain unsold at the termination of the
offering.
(4)
If the Registrant is a foreign private issuer, to file a post-effective
amendment to the Registration Statement to include any financial statements
required by Rule 3-19 of Regulation S-X at the start of any delayed offering or
throughout a continuous offering.
The
undersigned Registrant hereby undertakes that, for purposes of determining any
liability under the Securities Act of 1933, each filing of the Registrant's
annual report pursuant to Section 13(a) or 15(d) of the Securities Exchange Act
of 1934 (and, where applicable, each filing of an employee benefit plan's annual
report pursuant to Section 15(d) of the Securities Exchange Act of 1934) that is
incorporated by reference in the Registration Statement shall be deemed to be a
new Registration Statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.
Insofar as indemnification for liabilities arising under the Securities Act of
1933 may be permitted to directors, officers and controlling persons of the
Registrant pursuant to the foregoing provisions, or otherwise, the Registrant
has been advised that in the opinion of the Securities and Exchange Commission
such indemnification is against public policy as expressed in the Securities Act
of 1933 and is, therefore, unenforceable. In the event that a claim for
indemnification against such liabilities (other than the payment by the
Registrant of expenses incurred or paid by a director, officer or controlling
person of the Registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the Registrant will, unless in
the opinion of its counsel the matter has been settled by controlling precedent,
submit to a court of appropriate jurisdiction the question whether such
indemnification by it is against public policy as expressed in the Securities
Act of 1933 and will be governed by the final adjudication of such issue.
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, the Registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of San Diego, State of California, on May 9, 2002.
ALLIANCE PHARMACEUTICAL CORP.
(Registrant)
Date: May 9, 2002
By:
/s/ Theodore D. Roth
Theodore D. Roth
President and Chief Operating Officer
POWER OF ATTORNEY
KNOW
ALL MEN BY THESE PRESENTS, that each person whose signature appears below
constitutes and appoints Duane J. Roth and Theodore D. Roth, or either of them,
his true and lawful attorney-in-fact and agent, with full power of substitution
and resubstitution, for him and in his name, place and stead, in any and all
capacities, to sign any and all amendments to this Registration Statement, and
to file the same, with all exhibits thereto, and other documents in connection
therewith, with the Securities and Exchange Commission, granting unto said
attorney-in-fact and agent full power and authority to do and perform each and
every act and thing requisite and necessary to be done in and about the
premises, as fully to all intents and purposes as he might or could do in
person, hereby ratifying and confirming all that said attorney-in-fact, agent,
or their substitutes may lawfully do or cause to be done by virtue
hereof.
Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed by the following persons in the
capacities and on the dates indicated.
Signature
Title
Date
/s/ Duane J. Roth
Duane J. Roth
Chairman and Chief Executive Officer
May 9, 2002
/s/ Theodore D. Roth
Theodore D. Roth
Director, President and Chief
Operating Officer
May 9, 2002
/s/ Tim T. Hart
Tim T. Hart
Chief Financial Officer, Treasurer
and Chief Accounting Officer
May 9, 2002
/s/ Pedro Cuatrecasas, M.D.
Pedro Cuatrecasas, M.D.
Director
May 9, 2002
/s/ Fred M. Hershenson, Ph.D.
Fred M. Hershenson, Ph.D.
Director
May 9, 2002
/s/ Carroll O. Johnson
Carroll O. Johnson
Director
May 9, 2002
/s/ Stephen M. McGrath
Stephen M. McGrath
Director
May 9, 2002
/s/ Donald E. O'Neill
Donald E. O'Neill
Director
May 9, 2002
/s/ Helen M. Ranney, M.D.
Helen M. Ranney, M.D.
Director
May 9, 2002
/s/ Jean G. Riess, Ph.D.
Jean G. Riess, Ph.D.
Director
May 9, 2002
/s/ Thomas F. Zuck, M.D.
Thomas F. Zuck, M.D.
Director
May 9, 2002