from sense_hat import SenseHat
import time

sense = SenseHat()

sense.show_letter("O",text_colour=[255, 0, 0])
time.sleep(1)
sense.show_letter("M",text_colour=[0, 0, 255])
time.sleep(1)
sense.show_letter("G",text_colour=[0, 255, 0])
time.sleep(1)
sense.show_letter("!",text_colour=[0, 0, 0], back_colour=[255, 255, 255])
time.sleep(1)
sense.clear()

Create omg.py