The single base pair guanine insertion/deletion polymorphism ( 4G/5G ) within the promoter region of the PAI-1 gene influences PAI-1 synthesis and may modulate hepatic fibrogenesis .
O O O O O O O O O O O O O O O O B-GeneOrGeneProduct O O B-GeneOrGeneProduct O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O