BACKGROUND : Increase of the expression of g-globin gene and high production of fetal hemoglobin ( HbF ) in b-thalassemia patients is widely accepted as associated with a milder or even asymptomatic disease .
O O O O O O O B-GeneOrGeneProduct O O O O O B-GeneOrGeneProduct I-GeneOrGeneProduct O B-GeneOrGeneProduct O O B-DiseaseOrPhenotypicFeature B-OrganismTaxon O O O O O O O O O O O O O