RESULTS : Maternal diabetes significantly increased the levels of CHOP , calnexin , phosphorylated ( p ) -eIF2a , p-PERK , and p-IRE1a ; triggered XBP1 mRNA splicing ; and enhanced ER chaperone gene expression in WT embryos .
O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O O O O O B-GeneOrGeneProduct O B-GeneOrGeneProduct O O O O O I-GeneOrGeneProduct O I-GeneOrGeneProduct O O I-GeneOrGeneProduct O O B-GeneOrGeneProduct O O O O O O O O O O O O O