A model of liver metastasis was developed by intrasplenic injection of mouse colon cancer ( CMT-93 ) into AT1a knockout mice ( AT1aKO ) and wild-type ( C57BL/6 ) mice ( WT ) .
O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O O O O O O B-OrganismTaxon B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O B-CellLine O O B-GeneOrGeneProduct O B-OrganismTaxon O B-GeneOrGeneProduct O O O O B-CellLine O B-OrganismTaxon O O O O