P-21-activated kinases ( PAKs ) are serine/threonine kinases comprising six isoforms divided in two groups , group-I ( PAK1-3 ) /group-II ( PAK4-6 ) which play important roles in cell cytoskeletal dynamics , survival , secretion and proliferation and are activated by diverse stimuli .
B-GeneOrGeneProduct I-GeneOrGeneProduct O B-GeneOrGeneProduct O O B-GeneOrGeneProduct I-GeneOrGeneProduct O O O O O O O O O O B-GeneOrGeneProduct O O O B-GeneOrGeneProduct O O O O O O O O O O O O O O O O O O O O O O