The antinociception after morphine ( 3.2 mg/kg ) was increased by co-administration with CNSB002 from 28.0 and 31.7 % to 114.6 and 56.9 % reversal of hyperalgesia in the inflammatory and neuropathic models , respectively ( P < 0.01 ; one-way analysis of variance-significantly greater than either drug given alone ) .
O O O B-ChemicalEntity O O O O O O O O O B-ChemicalEntity O O O O O O O O O O O O B-DiseaseOrPhenotypicFeature O O B-DiseaseOrPhenotypicFeature O B-DiseaseOrPhenotypicFeature O O O O O O O O O O O O O O O O O O O O