The minor allele of SNP rs6232 was additionally associated with 15 % higher OGTT-derived and 19 % higher clamp-derived insulin sensitivity ( pdom < or= 0.0047 ) , 4.5 % lower HOMAIR ( pdom = 0.02 ) and 3.5 % lower 120-min glucose ( pdom = 0.0003 ) independently of BMI and proinsulin conversion .
O O O O O B-SequenceVariant O O O O O O O O O O O O O B-GeneOrGeneProduct O O O O O O O O O O O O O O O O O O O O O O B-ChemicalEntity O O O O O O O O O B-ChemicalEntity O O