These results demonstrated that PCE could induce dysplasia of fetal kidneys as well as glomerulosclerosis of adult offspring , and the low functional programming of renal AT2R might mediate the developmental origin of adult glomerulosclerosis .
O O O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O O O B-DiseaseOrPhenotypicFeature O O O O O O O O O O O B-GeneOrGeneProduct O O O O O O O B-DiseaseOrPhenotypicFeature O