L1503R is a member of group I mutation and has dominant-negative effect on secretion of full-length VWF multimers : an analysis of two patients with type 2A von Willebrand disease .
B-SequenceVariant O O O O O O O O O O O O O O O B-GeneOrGeneProduct O O O O O O B-OrganismTaxon O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O