Furthermore , p.A1369S was associated with a reduced risk of coronary heart disease ( OR 0.98 ; 95 % CI 0.96 , 0.99 ; P = 5.9 x 10 ( -4 ) ) .
O O B-SequenceVariant O O O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O O O O O O O O O O O O O O O O O O O O O