Both GcgR knockout ( Gcgr ( -/- ) ) mice and db/db mice that were administered GcgR monoclonal antibody displayed lower blood glucose levels accompanied by elevated plasma ghrelin levels .
O B-GeneOrGeneProduct O O B-GeneOrGeneProduct O O O O B-OrganismTaxon O O B-OrganismTaxon O O O B-GeneOrGeneProduct O O O O B-ChemicalEntity I-ChemicalEntity O O O O O B-GeneOrGeneProduct O O