We have analyzed skin lesions from RTRs with aggressive tumors for p53 gene modifications , the presence of Human Papillomas Virus ( HPV ) DNA in relation to the p53 codon 72 genotype and polymorphisms of the XPD repair gene .
O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O O O O B-DiseaseOrPhenotypicFeature O B-GeneOrGeneProduct O O O O O O B-OrganismTaxon I-OrganismTaxon I-OrganismTaxon O B-OrganismTaxon O O O O O O B-GeneOrGeneProduct O O O O O O O B-GeneOrGeneProduct O O O