Both sporadic and inherited BCCs are associated with mutations in the tumor suppressor gene PTCH1 , but there is still uncertainty on the role of its homolog PTCH2 .
O O O O B-DiseaseOrPhenotypicFeature O O O O O O B-DiseaseOrPhenotypicFeature O O B-GeneOrGeneProduct O O O O O O O O O O O O B-GeneOrGeneProduct O