To our knowledge , there is no previous report regarding whether domperidone , a peripheral dopamine D2 receptor antagonist , can also induce or aggravate symptoms of RLS .
O O O O O O O O O O O B-ChemicalEntity O O O B-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct O O O O O O O O O B-DiseaseOrPhenotypicFeature O