In this report the distribution of the exonic G/A single nucleotide polymorphism ( SNP ) in purine nucleoside phosphorylase ( PNP ) gene , resulting in the amino acid substitution serine to glycine at position 51 ( G51S ) , was investigated in a large population of AD patients ( n=321 ) and non-demented control ( n=208 ) .
O O O O O O O O B-SequenceVariant O O O O O O O B-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct O B-GeneOrGeneProduct O O O O O O O O O B-SequenceVariant I-SequenceVariant I-SequenceVariant I-SequenceVariant I-SequenceVariant I-SequenceVariant O B-SequenceVariant O O O O O O O O O B-DiseaseOrPhenotypicFeature B-OrganismTaxon O O O O O O O O O O