In this work we used SF188 and SJ-GBM2 cell lines to study the function of the ubiquitin carboxyl-terminal esterase L1 ( UCHL1 ) , a deubiquitinase de-regulated in several cancers , in pediatric high-grade gliomas .
O O O O O B-CellLine O B-CellLine O O O O O O O O B-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct O B-GeneOrGeneProduct O O O O O O O B-DiseaseOrPhenotypicFeature O O O O B-DiseaseOrPhenotypicFeature O