Although treatment with the pancreatic b-cell toxin streptozotocin induced hyperglycemia and raised plasma ghrelin levels in wild-type mice , hyperglycemia was averted in similarly treated Gcgr ( -/- ) mice and the plasma ghrelin level was further increased .
O O O O O O O B-ChemicalEntity O B-DiseaseOrPhenotypicFeature O O O B-GeneOrGeneProduct O O O B-OrganismTaxon O B-DiseaseOrPhenotypicFeature O O O O O B-GeneOrGeneProduct O O O B-OrganismTaxon O O O B-GeneOrGeneProduct O O O O O