As the antioxidant function of the Hp 2-2 protein is impaired , we sought to test the pharmacogenomic hypothesis that antioxidant vitamin E supplementation would provide cardiovascular protection to Hp 2-2 DM individuals .
O O O O O O B-GeneOrGeneProduct O O O O O O O O O O O O O B-ChemicalEntity B-ChemicalEntity I-ChemicalEntity O O O O O O B-GeneOrGeneProduct O B-DiseaseOrPhenotypicFeature O O