Object of the present study was to study the influence of SLCO1B1 * 5 , * 15 and * 15+C1007G , a novel haplotype found in a patient with pravastatin-induced myopathy , on the functional properties of OATP1B1 by transient expression systems of HEK293 and HeLa cells using endogenous conjugates and statins as substrates .
O O O O O O O O O O O B-GeneOrGeneProduct O O O O O O O I-SequenceVariant O O O O O O O B-OrganismTaxon O B-ChemicalEntity B-DiseaseOrPhenotypicFeature O O O O O O B-GeneOrGeneProduct O O O O O B-CellLine O B-CellLine O O O O O O O O O