The mutant receptor hGRalphaD401H did not exert a dominant positive or negative effect upon the wild-type receptor , it preserved its ability to bind to glucocorticoid response elements , and displayed a normal interaction with the glucocorticoid receptor-interacting protein 1 coactivator .
O O O B-GeneOrGeneProduct O O O O O O O O O O O O O O O O O O O O O B-ChemicalEntity O O O O O O O O O O B-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct O O