In contrast , CM of TNF-alpha-stimulate or BMP2-stimulated C4-2B cells induced in vitro mineralization of MC3T3-E1 osteoblast cells in a BMP-2-dependent and NF-kappaB-dependent manner , respectively .
O O O O O B-GeneOrGeneProduct O B-GeneOrGeneProduct B-CellLine O O O O O O B-CellLine O O O O B-GeneOrGeneProduct O B-GeneOrGeneProduct O O O O