In this study , 10 to 25 micromol/L curcumin inhibited 253JB-V and KU7 bladder cancer cell growth , and this was accompanied by induction of apoptosis and decreased expression of the proapoptotic protein survivin and the angiogenic proteins vascular endothelial growth factor ( VEGF ) and VEGF receptor 1 ( VEGFR1 ) .
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