More than 20 DNA mutations with different inheritance pattern have been described in patients with Bernard-Soulier Syndrome ( BSS ) , leading to abnormal or absent synthesis and/or expression of GPIbalpha .
O O O O O O O O O O O O O B-OrganismTaxon O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O B-DiseaseOrPhenotypicFeature O O O O O O O O O O O B-GeneOrGeneProduct O