As tranexamic acid is the only modifiable factor , its administration , particularly in doses exceeding 80 mg.kg ( -1 ) , should be weighed against the risk of postoperative seizures .
O B-ChemicalEntity I-ChemicalEntity O O O O O O O O O O O O O O O O O O O O O O O O O O O B-DiseaseOrPhenotypicFeature O