Although genomic studies suggest a link between MYC overexpression and B-cell receptor ( BCR ) signaling molecules in B-NHL , signaling pathways essential to Myc-mediated B-cell transformation have not been fully elucidated .
O O O O O O O B-GeneOrGeneProduct O O B-GeneOrGeneProduct I-GeneOrGeneProduct O B-GeneOrGeneProduct O O O O B-DiseaseOrPhenotypicFeature O O O O O B-GeneOrGeneProduct O O O O O O O O