Furthermore , EPZ015666 restrained the phosphorylation of IkB kinaseb and IkBa , as well as nucleus transsituation of p65 as well as AKT in FLSs .
O O B-ChemicalEntity O O O O B-GeneOrGeneProduct I-GeneOrGeneProduct O B-GeneOrGeneProduct O O O O O O O B-GeneOrGeneProduct O O O B-GeneOrGeneProduct O O O