Whereas allele frequencies for the other two polymorphisms did not differ significantly between any of the groups , the 111G allele frequency was significantly higher in subjects with extreme morning preference ( 0.14 ) than in subjects with extreme evening preference ( 0.03 ) ( Fisher 's exact test , two-sided P value=0.031 , odds ratio=5.67 ) .
O O O O O O O O O O O O O O O O O O O B-SequenceVariant O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O