The present study sought to characterize the cognitive-enhancing effects of the 5-HT ( 6 ) antagonist Ro4368554 ( 3-benzenesulfonyl-7- ( 4-methyl-piperazin-1-yl ) 1H-indole ) in a rat object recognition task employing a cholinergic ( scopolamine pretreatment ) and a serotonergic- ( tryptophan ( TRP ) depletion ) deficient model , and compared its pattern of action with that of the acetylcholinesterase inhibitor metrifonate .
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