Knockdowns of NOTCH1 , SOX10 , and their common effector FABP7 had negative effects on each other , inhibited spheroidogenesis , and induced cell death pointing at their essential roles in CSC maintenance .
O O B-GeneOrGeneProduct O B-GeneOrGeneProduct O O O O O B-GeneOrGeneProduct O O O O O O O O O O O O O O O O O O O O O O O