BACKGROUND : The aim of the study was to investigate the antihypertensive effects of angiotensin II type-1 receptor blocker , losartan , and its potential in slowing down renal disease progression in spontaneously hypertensive rats ( SHR ) with adriamycin ( ADR ) nephropathy .
O O O O O O O O O O O O O O B-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct O O B-ChemicalEntity O O O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O O O B-DiseaseOrPhenotypicFeature B-OrganismTaxon O O O O B-ChemicalEntity O B-ChemicalEntity O B-DiseaseOrPhenotypicFeature O