Comparison of the two biopsies showed that temsirolimus inhibited tumor cell proliferation through cell cycle arrest , but did not induce any change in the number of apoptotic tumor cells .
O O O O O O O B-ChemicalEntity O B-DiseaseOrPhenotypicFeature O O O O O O O O O O O O O O O O O O B-DiseaseOrPhenotypicFeature O O