Top canonical pathways identified by Ingenuity Pathway Analysis ( IPA ) included `` Clathrin-mediated Endocytosis Signaling '' ( p = 5.14x10-4 ) , `` Virus Entry via Endocytic Pathways '' ( p = 6.15x 10-4 ) , and `` High Mobility Group-Box 1 ( HMGB1 ) Signaling ''
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