RESULTS : Family-based TDT showed a significant association of SLE with a N673S polymorphism in the P-selectin gene ( SELP ) ( P = 5.74 x 10 ( -6 ) ) and a C203S polymorphism in the interleukin-1 receptor-associated kinase 1 gene ( IRAK1 ) ( P = 9.58 x 10 ( -6 ) ) .
O O O O O O O O O B-DiseaseOrPhenotypicFeature O O B-SequenceVariant O O O B-GeneOrGeneProduct O O B-GeneOrGeneProduct O O O O O O O O O O O O O B-SequenceVariant O O O B-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct O O B-GeneOrGeneProduct O O O O O O O O O O O O