Patients with essential hypertension ( mean sitting diastolic BP [ MSDBP ] , > or =95 mm Hg and < 110 mm Hg ) were randomized to 1 of 8 treatment groups : VAL 160 or 320 mg ; HCTZ 12.5 or 25 mg ; VAL/HCTZ 160/12.5 , 320/12.5 , or 320/25 mg ; or placebo .
B-OrganismTaxon O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O O O O O O O O O O O O O O O O O O O O O O O O O O O O O B-ChemicalEntity O O O O O B-ChemicalEntity O O O O O I-ChemicalEntity O O O O O O O O O O O