Homozygous mutations in PLCE1 ( also known as KIAA1516 , PLCE , or NPHS3 ) were identified following genome-wide mapping of single-nucleotide polymorphisms .
O O O B-GeneOrGeneProduct O O O O B-GeneOrGeneProduct O B-GeneOrGeneProduct O O B-GeneOrGeneProduct O O O O O O O O O O