We conclude that mPGES-1-derived PGE ( 2 ) mediates lithium-induced polyuria likely via inhibition of AQP2 and NKCC2 expression .
O O O B-GeneOrGeneProduct B-ChemicalEntity I-ChemicalEntity I-ChemicalEntity I-ChemicalEntity O B-ChemicalEntity B-DiseaseOrPhenotypicFeature O O O O B-GeneOrGeneProduct O B-GeneOrGeneProduct O O