Proprotein convertase subtilisin/kexin type 9 ( PCSK9 ) is at a locus for autosomal dominant hypercholesterolemia , and recent data indicate that the PCSK9 gene is involved in cholesterol biosynthesis .
B-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct O B-GeneOrGeneProduct O O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O O O O O O O B-GeneOrGeneProduct O O O O B-ChemicalEntity O O