It remains to be seen whether such pre-existing antiviral mutations could result in widespread emergence of HBV resistant strains when lamivudine-containing highly active antiretroviral ( ARV ) treatment ( HAART ) regimens become widely applied in South Africa , as this is likely to have potential implications in the management of HBV-HIV co-infected patients .
O O O O O O O O O O O O O O O O B-OrganismTaxon O O O B-ChemicalEntity O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature B-OrganismTaxon O