We hypothesized that disrupting the cognate type I IFN receptor ( type I IFN a/b receptor [ IFNAR ] ) to interrupt IFN signaling would prevent or delay the development of virus-induced diabetes .
O O O O O O B-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct O B-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct O B-GeneOrGeneProduct O O O O B-GeneOrGeneProduct O O O O O O O O O B-DiseaseOrPhenotypicFeature O