CONCLUSIONS : The symptoms of infertility observed in the DMC1 homozygote mutation carrier and in both patients with a heterozygous substitution in exon 2 of the MSH5 gene provide indirect evidence of the role of genes involved in meiotic recombination in the regulation of ovarian function .
O O O O O B-DiseaseOrPhenotypicFeature O O O B-GeneOrGeneProduct O O O O O O B-OrganismTaxon O O O O O O O O O B-GeneOrGeneProduct O O O O O O O O O O O O O O O O O O O O