The goal of this study was to define the identities , origins and frequencies of TMC1 mutations in an expanded cohort of 557 large Pakistani families segregating recessive deafness .
O O O O O O O O O O O O O O O B-GeneOrGeneProduct O O O O O O O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O