Materials and METHODS : A cohort of 1163 unrelated patients with IBD ( 874 Crohn 's disease , 259 ulcerative colitis , 30 indeterminate colitis ) and 312 controls were analysed for anti-Saccharomyces cerevisiae antibodies ( gASCA ) IgG , anti-laminaribioside antibodies ( ALCA ) IgG , anti-chitobioside antibodies ( ACCA ) IgA , anti-mannobioside antibodies ( AMCA ) IgG and outer membrane porin ( Omp ) IgA and were genotyped for variants in NOD2/CARD15 , TUCAN/CARDINAL/CARD8 , NOD1/CARD4 , TLR4 , TLR1 , TLR2 and TLR6 .
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