There are differential effects of age , gender and smoking status on the association of the G-395A polymorphism with EH ; the G-395A polymorphism is significantly associated with EH in subjects over 60years old , in females and in nonsmokers .
O O O O O O O O O O O O O O O O B-SequenceVariant O O B-DiseaseOrPhenotypicFeature O O B-SequenceVariant O O O O O B-DiseaseOrPhenotypicFeature O O O O O O O O O O O O