In an attempt to improve developmental delay and alleviate symptoms of hypothyroidism , patients are receiving varying doses and durations of T4 treatment , but responses have been inconsistent so far .
O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O O O O B-DiseaseOrPhenotypicFeature O B-OrganismTaxon O O O O O O O B-ChemicalEntity O O O O O O O O O O