Taken together , the results suggest that mutual interactions between these factors may be pivotal not only in enhancing the osteomimicry and metastatic potential of PC cells , but also in bone remodeling and in shifting the balance from osteoclastogenesis towards osteoblastogenesis .
O O O O O O O O O O O O O O O O O O O O O O O O O B-DiseaseOrPhenotypicFeature O O O O O O O O O O O O O O O O O