The aim of this study was to investigate whether single nucleotide polymorphisms ( SNPs ) in the genes regulating insulin secretion ( SLC2A2 [ encoding GLUT2 ] , GCK , TCF1 [ encoding HNF-1alpha ] , HNF4A , GIP , and GLP1R ) are associated with the conversion from impaired glucose tolerance ( IGT ) to type 2 diabetes in participants of the Finnish Diabetes Prevention Study .
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