We performed 2 sets of case-control comparisons using Japanese subjects ( first set : 830 patients with RA and 658 controls ; second set : 1112 patients with RA and 940 controls ) , and then performed a stratified analysis using human leukocyte antigen ( HLA ) -DRB1 shared epitope ( SE ) status .
O O O O O O O O O O O O O O O B-OrganismTaxon O B-DiseaseOrPhenotypicFeature O O O O O O O O B-OrganismTaxon O B-DiseaseOrPhenotypicFeature O O O O O O O O O O O O B-OrganismTaxon B-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct O O O O O O O