The majority of CXCR5 ( + ) PD1 ( + ) CD4 ( + ) T follicular helper ( Tfh ) cells ( > 90 % ) are CD25 ( - ) Bcl6 ( hi ) , while a small subpopulation ( < 10 % ) are CD25 ( + ) Bcl6 ( low ) but do not express FoxP3 and are not T regulatory cells .
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