Normoxic cancer cells import and metabolize lactate , resulting in upregulation of mTOR signaling via glutamine metabolism enhanced by lactate catabolism .
B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O O O O B-ChemicalEntity O O O O O B-GeneOrGeneProduct O O B-ChemicalEntity O O O B-ChemicalEntity O O