Point mutations in the BICD2 gene have been identified in patients with a dominant form of spinal muscular atrophy , but how these mutations cause disease is unknown .
O O O O B-GeneOrGeneProduct O O O O O B-OrganismTaxon O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O O O O O O O O O O