This generates a conformational shift in the p17 R76G mutant which enables a functional epitope ( s ) , masked in refp17 , to elicit B-cell growth-promoting signals after its interaction with a still unknown receptor ( s ) .
O O O O O O O B-GeneOrGeneProduct B-SequenceVariant O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O