CONCLUSION : Our results suggest that use of high-dose TXA in older patients in conjunction with cardiopulmonary bypass and open-chamber cardiac surgery is associated with clinical seizures in susceptible patients .
O O O O O O O O O B-ChemicalEntity O O B-OrganismTaxon O O O O O O O O O O O O O B-DiseaseOrPhenotypicFeature O O B-OrganismTaxon O