Inhibition of PRMT5 by EPZ015666 and siRNA-mediated knockdown reduced IL-6 and IL-8 production , and proliferation of RA FLSs .
O O B-GeneOrGeneProduct O B-ChemicalEntity O O O O B-GeneOrGeneProduct O B-GeneOrGeneProduct O O O O O B-DiseaseOrPhenotypicFeature O O