Similarly , the total protein abundance of the Na-K-2Cl cotransporter ( NKCC2 ) in the medulla but not in the cortex of the +/+ mice was significantly reduced by lithium treatment .
O O O O O O O O B-GeneOrGeneProduct I-GeneOrGeneProduct O B-GeneOrGeneProduct O O O O O O O O O O O O B-OrganismTaxon O O O O B-ChemicalEntity O O