Recently , we identified the selenoprotein N gene ( SEPN1 ) as responsible for SEPN-related myopathy ( SEPN-RM ) , a unique early-onset myopathy formerly divided in two different nosological categories : rigid spine muscular dystrophy and the severe form of classical multiminicore disease .
O O O O O B-GeneOrGeneProduct I-GeneOrGeneProduct O O B-GeneOrGeneProduct O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O B-DiseaseOrPhenotypicFeature O O O O O B-DiseaseOrPhenotypicFeature O O O O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O