We observed a time-dependent increase in mRNA and protein expression of the pro-apoptotic and pro-inflammatory HIF-1a target genes MCP1 , BNIP3 , Nix and Noxa during TD .
O O O O O O O O O O O O O O I-DiseaseOrPhenotypicFeature B-GeneOrGeneProduct O O B-GeneOrGeneProduct O B-GeneOrGeneProduct O B-GeneOrGeneProduct O B-GeneOrGeneProduct O B-DiseaseOrPhenotypicFeature O