To determine whether atorvastatin attenuated CIN , the inflammatory response and apoptosis in vivo and in vitro , a rat model of iopamidol-induced CIN was used , and human embryonic proximal tubule ( HK2 ) cell damage was assessed .
O O O B-ChemicalEntity O B-DiseaseOrPhenotypicFeature O O B-DiseaseOrPhenotypicFeature O O O O O O O O O O B-OrganismTaxon O O B-ChemicalEntity B-DiseaseOrPhenotypicFeature O O O O B-OrganismTaxon O O O O B-CellLine O O O O O O