This effect was dependent on the production of IL-10 from DCs , as neither DCs isolated from IL-10-/- mice nor IL-10-neutralized DCs generated tolerogenic DCs .
O O O O O O O O B-GeneOrGeneProduct O O O O O O O O B-GeneOrGeneProduct B-OrganismTaxon O B-GeneOrGeneProduct O O O O O