The data indicate that phenylephrine-induced hypertension instituted 2 h after MCAO does not aggravate edema in the ischemic core , that it improves edema in the periphery of the ischemic territory , and that it reduces the area of histochemical neuronal dysfunction .
O O O O B-ChemicalEntity B-DiseaseOrPhenotypicFeature O O O O B-DiseaseOrPhenotypicFeature O O O B-DiseaseOrPhenotypicFeature O O B-DiseaseOrPhenotypicFeature O O O O O B-DiseaseOrPhenotypicFeature O O O O O B-DiseaseOrPhenotypicFeature O O O O O O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O