RESULTS : Direct sequencing of the encoding regions of the candidate genes revealed a heterozygous mutation c.592C -- > T in exon 2 of the gap junction protein , alpha 8 ( GJA8 ) gene .
O O O O O O O O O O O O O O O O B-SequenceVariant I-SequenceVariant I-SequenceVariant I-SequenceVariant O O O O O B-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct O B-GeneOrGeneProduct O O O