We investigated the association between chronic ITP and the frequency of the single-nucleotide polymorphism rs763780 ( 7488T/C ) , which causes a His-to-Arg substitution at amino acid 161 .
O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O O O O O O O B-SequenceVariant O B-SequenceVariant O O O O O B-SequenceVariant I-SequenceVariant I-SequenceVariant I-SequenceVariant I-SequenceVariant I-SequenceVariant O