In patient fibroblasts , raising VLCAD activity to approximately 20 % of normal control fibroblast activity raised palmitic acid beta-oxidation flux to the level found in control fibroblasts , which may offer important information for the rational design of future somatic gene therapy for VLCAD deficiency ..
O B-OrganismTaxon O O O B-GeneOrGeneProduct O O O O O O O O O O O B-ChemicalEntity I-ChemicalEntity O O O O O O O O O O O O O O O O O O O O O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O