CONCLUSIONS : As a potential explanation of our findings , we hypothesize that in b-thalassemia the Gg-globin-XmnI/Ag-globin- ( G- > A ) genotype is frequently under genetic linkage with b ( 0 ) -thalassemia mutations , but not with the b ( + ) -thalassemia mutation here studied ( i.e .
O O O O O O O O O O O O O O B-DiseaseOrPhenotypicFeature O B-GeneOrGeneProduct O B-SequenceVariant I-SequenceVariant I-SequenceVariant O O O O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O O O O O O