Mutations of the steroid 5alpha-reductase type 2 ( SRD5A2 ) gene in 46 , XY subjects cause masculinization defects of varying degrees , due to reduced or impaired enzymatic activity .
O O O B-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct O B-GeneOrGeneProduct O O O O O O O O O O O O O O O O O O O O O O