Ten consecutive patients ( mean age , 58.4 +/- 6.8 years ; 7 men , 3 women ) with similar characteristics at the duration of disease ( mean disease time , 8.4 +/- 3.5 years ) , disabling motor fluctuations ( Hoehn _ Yahr stage 3-5 in off-drug phases ) and levodopa-induced dyskinesias were selected .
O O B-OrganismTaxon O O O O O O O O O O B-OrganismTaxon O O B-OrganismTaxon O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O B-ChemicalEntity B-DiseaseOrPhenotypicFeature O O O