The pathogenesis of human type 1 diabetes , characterized by immune-mediated damage of insulin-producing b-cells of pancreatic islets , may involve viral infection .
O O O B-OrganismTaxon B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O O O O O O B-GeneOrGeneProduct O O O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O