Immunoblotting , immunohistochemistry , and quantitative ( q ) RT-PCR consistently detected a significant decrease in aquaporin-2 ( AQP2 ) protein expression in both the renal cortex and medulla of lithium-treated +/+ mice .
O O O O O O O O O O O O O O O O B-GeneOrGeneProduct O B-GeneOrGeneProduct O O O O O O O O O O O B-ChemicalEntity O B-OrganismTaxon O