To analyse the in vivo function of TAK1 in cartilage , we generated mice with a conditional deletion of Tak1 driven by the collagen 2 promoter .
O O O O O O O B-GeneOrGeneProduct O O O O O B-OrganismTaxon O O O O O B-GeneOrGeneProduct O O O B-GeneOrGeneProduct I-GeneOrGeneProduct O O