There was a significant difference in insulin sensitivity index among groups ( F ( 33 ) = 10.66 ; P < .001 ) ( clozapine < olanzapine < risperidone ) , with subjects who received clozapine and olanzapine exhibiting significant insulin resistance compared with subjects who were treated with risperidone ( clozapine vs risperidone , t ( 33 ) = -4.29 ; P < .001 ; olanzapine vs risperidone , t ( 33 ) = -3.62 ; P = .001 [ P < .001 ] ) .
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