We also detected p.R34X among normal control samples of African-American and northern European origins , raising the possibility that p.R34X and other mutations of TMC1 are prevalent contributors to the genetic load of deafness across a variety of populations and continents .
O O O B-SequenceVariant O O O O O O O O O O O O O O O B-SequenceVariant O O O O B-GeneOrGeneProduct O O O O O O O O B-DiseaseOrPhenotypicFeature O O O O O O O O