Conversely , when podocytes were cultured in high glucose ( 20 mM ) , stepwise oxidative phosphorylation biogenesis was aborted , and a glycolytic switch occurred , with consecutive lactic acidosis .
O O O O O O O O B-ChemicalEntity O O O O O O O O O O O O O O O O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O