Adult male albino rats , treated with ISO ( 200 mg/kg , s.c. ) for 2 days at an interval of 24 h caused a significant ( P < 0.05 ) elevation of heart weight , serum marker enzymes , lipid peroxidation and Ca+2 ATPase level whereas there was a significant ( P < 0.05 ) decrease in body weight , endogenous antioxidants , Na+/ K+ ATPase and Mg+2 ATPase levels .
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