Proinflammatory cytokine gene polymorphisms have been demonstrated to associate with gastric cancer risk , of which IL1B-31T/C and -511C/T changes have been well investigated due to the possibility that they may alter the IL1B transcription .
B-GeneOrGeneProduct I-GeneOrGeneProduct O O O O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O O O O I-SequenceVariant O B-SequenceVariant O O O O O O O O O O O O O O B-GeneOrGeneProduct O O