OBJECTIVE : This study investigated the efficacy and tolerability of valsartan ( VAL ) or hydrochlorothiazide ( HCTZ ) -monotherapy and higher-dose combinations in patients with essential hypertension .
O O O O O O O O O O B-ChemicalEntity O B-ChemicalEntity O O B-ChemicalEntity O B-ChemicalEntity O O O O O O B-OrganismTaxon O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O