SSCP followed by DNA sequencing revealed TP53 mutations in 16 of 73 ( 22 % ) glioblastomas and PTEN mutations in 13 of 63 ( 21 % ) cases analyzed .
O O O O O O B-GeneOrGeneProduct O O O O O O O O O B-DiseaseOrPhenotypicFeature O B-GeneOrGeneProduct O O O O O O O O O O O O