To this end , doxorubicin ( 15 mug/g body wt ) was injected intravenously into gene-targeted mice lacking SGK1 ( sgk1 ( -/- ) ) and their wild-type littermates ( sgk1 ( +/+ ) ) .
O O O O B-ChemicalEntity O O O O O O O O O O O B-OrganismTaxon O B-GeneOrGeneProduct O B-GeneOrGeneProduct O O O O O O O O O B-GeneOrGeneProduct O O O O O