A detailed analysis of the DNA breakpoints in the two genes , previously characterized by other groups , validated the observation that Alu-mediated unequal recombination is the main type of deletion in MSH2 ( n=34 ) , but not in MLH1 ( n=21 ) ( P < 0.0001 ) .
O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O B-GeneOrGeneProduct O O O O O O O B-GeneOrGeneProduct O O O O O O O O O