METHODS : The single nucleotide polymorphisms ( SNP ) at positions -1123 ( rs2488457 ) , +1858 ( rs2476601 , the R620W substitution ) , and +2740 ( rs1217412 ) were genotyped using TaqMan assays in 372 subjects with childhood-onset T1D , 130 subjects with JIA , and 400 control subjects of Czech origin , and in 160 subjects with T1D and 271 healthy controls of Azeri origin .
O O O O O O O O O O O O O B-SequenceVariant O O O O B-SequenceVariant O O B-SequenceVariant O O O O O O B-SequenceVariant O O O O O O O O O O O B-DiseaseOrPhenotypicFeature O O O O B-DiseaseOrPhenotypicFeature O O O O O O O O O O O O O O B-DiseaseOrPhenotypicFeature O O O O O O O O