Radiation modulates both tumor cells and immune cells in the tumor microenvironment to exert its anti-tumor activity ; however , the molecular connection between tumor cells and immune cells that mediates radiation-exerted tumor suppression activity in the tumor microenvironment is largely unknown .
O O O B-DiseaseOrPhenotypicFeature O O O O O O B-DiseaseOrPhenotypicFeature O O O O I-DiseaseOrPhenotypicFeature O O O O O O O O B-DiseaseOrPhenotypicFeature O O O O O O O B-DiseaseOrPhenotypicFeature O O O O B-DiseaseOrPhenotypicFeature O O O O O