The incidence of hypokalemia was lower with VAL/HCTZ combinations ( 1.8 % -6.1 % ) than with HCTZ monotherapies ( 7.1 % -13.3 % ) .
O O O B-DiseaseOrPhenotypicFeature O O O I-ChemicalEntity O O O O O O O O O B-ChemicalEntity O O O O O O O O