Replication-competent HBV strains with sG145R or sP120T and LAM resistance ( rtM204I or rtL180M/rtM204V ) were generated on an HBeAg-positive and an HBeAg-negative background with precore ( PC ) and basal core promoter ( BCP ) mutants .
O B-OrganismTaxon O O I-SequenceVariant O I-SequenceVariant O B-ChemicalEntity O O I-SequenceVariant O I-SequenceVariant O O O O O B-ChemicalEntity O O B-ChemicalEntity O O B-GeneOrGeneProduct O B-GeneOrGeneProduct O O O O O O O O O O