Expression of the master regulators of oxidative metabolism transcription factor A mitochondrial , PGC-1a , AMPK , and serine-threonine liver kinase B1 was altered by high glucose , as well as their downstream signaling networks .
O O O B-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct O B-GeneOrGeneProduct O B-GeneOrGeneProduct O O B-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct O O O O B-ChemicalEntity O O O O O O O O O