PAK2 was activated by some pancreatic growth-factors [ EGF , PDGF , bFGF ] , by secretagogues activating phospholipase-C ( PLC ) [ CCK , carbachol , bombesin ] and by post-receptor stimulants activating PKC [ TPA ] , but not agents only mobilizing cellular calcium or increasing cyclic AMP .
B-GeneOrGeneProduct O O O O B-GeneOrGeneProduct I-GeneOrGeneProduct O B-GeneOrGeneProduct O B-GeneOrGeneProduct O B-GeneOrGeneProduct O O O O O B-GeneOrGeneProduct O B-GeneOrGeneProduct O O B-GeneOrGeneProduct O B-ChemicalEntity O B-ChemicalEntity O O O O O O B-GeneOrGeneProduct O B-ChemicalEntity O O O O O O O O B-ChemicalEntity O O B-ChemicalEntity I-ChemicalEntity O