Two coding polymorphisms , 55M/L and 192Q/R , and a promoter variant , -107C/T , has been extensively studied with respect to susceptibility to CHD .
O O O O B-SequenceVariant O B-SequenceVariant O O O O O O B-SequenceVariant O O O O O O O O O O B-DiseaseOrPhenotypicFeature O