CONCLUSIONS : Overall , these results suggest that KCa3.1 is involved in the regulation of Ca2+ homeostasis in astrocytes and attenuation of the UPR and ER stress , thus contributing to memory deficits and neuronal loss .
O O O O O O O O B-GeneOrGeneProduct O O O O O O B-ChemicalEntity O O O O O O O O O O O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O