Quantitative cDNA expression of normal human VLCAD was performed in the patients fibroblasts , using vaccinia viral system , which demonstrated that the deficiency of the normal VLCAD protein causes impaired long-chain fatty acid beta-oxidation activity in the patients fibroblasts .
O O O O O B-OrganismTaxon B-GeneOrGeneProduct O O O O B-OrganismTaxon O O O O O O O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O O B-ChemicalEntity I-ChemicalEntity I-ChemicalEntity O O O O B-OrganismTaxon O O