A g-secretase inhibitor , DAPT , selectively depleted CD133 ( + ) cells , suppressed N1ICD and SKP2 , induced p27Kip1 , inhibited ACC growthin vivo , and sensitized CD133 ( + ) cells to radiation .
O B-GeneOrGeneProduct O O B-ChemicalEntity O O O B-GeneOrGeneProduct O O O O O O B-GeneOrGeneProduct O B-GeneOrGeneProduct O O B-GeneOrGeneProduct O O B-DiseaseOrPhenotypicFeature O O O O O B-GeneOrGeneProduct O O O O O O O