Moreover , the abundance and proliferative index of lymph node , thymus and CNS CD4 ( + ) CD25 ( + ) FoxP3 ( + ) Tregs were strikingly reduced in VPAC2-deficient mice with EAE .
O O O O O O O O O O O O O O B-GeneOrGeneProduct O O O B-GeneOrGeneProduct O O O B-GeneOrGeneProduct O O O O O O O O B-GeneOrGeneProduct B-OrganismTaxon O B-DiseaseOrPhenotypicFeature O