The AS isoform lacks exon 8 , and is deduced to contain 49 amino acid changes in the membrane-distal portion of the extracellular domain , where considerable amino acid changes are known in CD72 ( c ) allele associated with murine SLE .
O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O B-GeneOrGeneProduct O O O O O O B-OrganismTaxon B-DiseaseOrPhenotypicFeature O