CONCLUSIONS : While mutations were absent in non-GH-secreting adenoma patients , germline AIP mutations can be found in children and adolescents with GH-secreting tumours , even in the absence of family history .
O O O O O O O I-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature B-OrganismTaxon O O B-GeneOrGeneProduct O O O O O O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O O O O O O O O O