This , together with our previous findings that allopurinol failed to prevent adrenocorticotrophic hormone induced hypertension , suggests that XO activity is not a major determinant of GC-HT in the rat .
O O O O O O O O B-ChemicalEntity O O O B-GeneOrGeneProduct I-GeneOrGeneProduct O B-DiseaseOrPhenotypicFeature O O O B-ChemicalEntity O O O O O O O B-ChemicalEntity O O B-OrganismTaxon O