We conclude that defects in O-GlcNAc homeostasis and host cell factor 1 proteolysis may play roles in mediation of XLID in individuals with OGT mutations .
O O O O O B-GeneOrGeneProduct O O B-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct I-GeneOrGeneProduct O O O O O O O B-DiseaseOrPhenotypicFeature O O O B-GeneOrGeneProduct O O