Here , Wistar Kyoto/spontaneous hypertensive ( WKY/SHR ) rats fed a high-salt diet developed severe proteinuria , resulting from pronounced renal inflammation , fibrosis and tubular epithelial cell apoptosis .
O O O O B-DiseaseOrPhenotypicFeature O O O B-OrganismTaxon O O I-ChemicalEntity O O O B-DiseaseOrPhenotypicFeature O O O O B-DiseaseOrPhenotypicFeature I-DiseaseOrPhenotypicFeature O B-DiseaseOrPhenotypicFeature O O O O O O