It was partially reduced by PKC- or Src-inhibition , but not with PI3K-inhibitors ( wortmannin , LY294002 ) or thapsigargin .
O O O O O B-GeneOrGeneProduct O B-GeneOrGeneProduct O O O O B-GeneOrGeneProduct O B-ChemicalEntity O B-ChemicalEntity O O B-ChemicalEntity O