Both minor alleles , adjusted for sex , age , BMI and insulin sensitivity were associated with elevated AUCproinsulin and AUCproinsulin/AUCinsulin ( rs6235 : p ( additive ) model < or= 0.009 , effect sizes 8/8 % , rs6232 : pdominant model < or= 0.01 , effect sizes 10/21 % ) .
O O O O O O O O O O O O B-GeneOrGeneProduct O O O O O I-ChemicalEntity O I-ChemicalEntity O B-SequenceVariant O O O O O O O O O O O O O O O B-SequenceVariant O O O O O O O O O O O O O