'''
Moldoveanu Davide
Pangram
'''

alphabet = "abcdefghijklmnopqrstuvwxyz"
  
def IsPangram(str_):
    for char in alphabet:
        if char not in str_.lower():
            return False
  
    return True


def main():

    string = input("Inserisci una frase: ")
    if(IsPangram(string) == True):
        print("Yes")
    else:
        print("No")


if __name__ == "__main__":
    main()