"""Scoring functions for guideRNAs"""

MISMATCH_PENALTIES = [0, 0, 0.014, 0, 0, 0.395, 0.317, 0, 0.389, 0.079, 0.445, 0.508, 0.613, 0.851, 0.732, 0.828, 0.615, 0.804, 0.685, 0.583]
#penalties are determined experimentally in Hsu et al., Nature Biotechnology 2013

