with open("E:/shpro/Output.txt", "a+", encoding='utf-8') as text_file:
    text_file.write('User_Name: '+str(1))
    text_file.write('User_Name: '+str(2))
    text_file.write('User_Name: '+str(3))
    text_file.write('User_Name: '+str(4))
with open("E:/shpro/Output.txt", "a+", encoding='utf-8') as text_file:
    text_file.write('User_Name: '+str(11))
    text_file.write('User_Name: '+str(21))
    text_file.write('User_Name: '+str(31))
    text_file.write('User_Name: '+str(41))
with open("E:/shpro/Output.txt", "a+", encoding='utf-8') as text_file:
    text_file.write('User_Name: '+str(111))
    text_file.write('User_Name: '+str(211))
    text_file.write('User_Name: '+str(311))
    text_file.write('User_Name: '+str(411))