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1-hop neighbor's text information: Title: Modifications of glucose storage and oxidation in nonobese diabetics, measured by continuous indirect calorimetry.
Abstract: A new application of continuous indirect calorimetry is described for measuring the disposal of a glucose load. In a group of 10 normal subjects, 3 h aft... | 2 | Diabetes Mellitus Type 2 | pubmed | 2,111 | test |
1-hop neighbor's text information: Title: A reappraisal of the blood glucose homeostat which comprehensively explains the type 2 diabetes mellitus-syndrome X complex.
Abstract: Blood glucose concentrations are unaffected by exercise despite very high rates of glucose flux. The plasma ionised calcium levels are even mor... | 2 | Diabetes Mellitus Type 2 | pubmed | 4,178 | test |
1-hop neighbor's text information: Title: Precursor frequencies of T-cells reactive to insulin in recent onset type 1 diabetes mellitus.
Abstract: T-cell mediated autoimmune beta-cell destruction is an important component of type 1 diabetes (T1D) and insulin is a critical antigen recognized by autoreactive T-cells. The... | 1 | Diabetes Mellitus Type 1 | pubmed | 11,839 | test |
1-hop neighbor's text information: Title: Misleading plasma electrolytes in diabetic children with severe hyperlipidaemia.
Abstract: Severe abnormalities of plasma electrolyte concentrations were observed in 4 children who had massive hyperlipidaemia secondary to poorly-controlled, insulin-dependent diabetes mellitus. ... | 1 | Diabetes Mellitus Type 1 | pubmed | 218 | test |
1-hop neighbor's text information: Title: Polyol pathway and modulation of ischemia-reperfusion injury in Type 2 diabetic BBZ rat hearts.
Abstract: We investigated the role of polyol pathway enzymes aldose reductase (AR) and sorbitol dehydrogenase (SDH) in mediating injury due to ischemia-reperfusion (IR) in Type 2 dia... | 0 | Experimental | pubmed | 8,827 | test |
1-hop neighbor's text information: Title: Intravenous intralipid-induced blood pressure elevation and endothelial dysfunction in obese African-Americans with type 2 diabetes.
Abstract: OBJECTIVE: Increased free fatty acids (FFAs) are leading candidates in the pathogenesis of insulin resistance and hypertension in obese... | 2 | Diabetes Mellitus Type 2 | pubmed | 2,937 | test |
1-hop neighbor's text information: Title: Epidemiology of Diabetes Interventions and Complications (EDIC). Design, implementation, and preliminary results of a long-term follow-up of the Diabetes Control and Complications Trial cohort.
Abstract: OBJECTIVE: The Diabetes Control and Complications Trial (DCCT) demonstrate... | 1 | Diabetes Mellitus Type 1 | pubmed | 12,938 | test |
1-hop neighbor's text information: Title: Effects of combined neutral endopeptidase 24-11 and angiotensin-converting enzyme inhibition on femoral vascular conductance in streptozotocin-induced diabetic rats.
Abstract: 1. The successive effects of the angiotensin-converting enzyme inhibitor captopril (CAP, 2 mg kg(-1)+1... | 0 | Experimental | pubmed | 2,235 | test |
1-hop neighbor's text information: Title: Combined effects of single-nucleotide polymorphisms in GCK, GCKR, G6PC2 and MTNR1B on fasting plasma glucose and type 2 diabetes risk.
Abstract: AIMS/HYPOTHESIS: Variation in fasting plasma glucose (FPG) within the normal range is a known risk factor for the development of type... | 2 | Diabetes Mellitus Type 2 | pubmed | 12,549 | test |
1-hop neighbor's text information: Title: Effect of insulin treatment on smooth muscle contractility and endothelium-dependent relaxation in rat aortae from established STZ-induced diabetes.
Abstract: 1. This study involved the chronic administration of low or high insulin to rats with established streptozotocin (STZ)-... | 0 | Experimental | pubmed | 5,934 | test |
1-hop neighbor's text information: Title: Brisk walking compared with an individualised medical fitness programme for patients with type 2 diabetes: a randomised controlled trial.
Abstract: AIMS/HYPOTHESIS: Structured exercise is considered a cornerstone in type 2 diabetes treatment. However, adherence to combined resi... | 2 | Diabetes Mellitus Type 2 | pubmed | 13,458 | test |
1-hop neighbor's text information: Title: Cardiac pathology in the hypertensive diabetic rat. Biventricular damage with right ventricular predominance.
Abstract: The hypertensive-diabetic rat is a new small animal model of cardiomyopathy characterized by ventricular damage. To determine the extent of pathology in this ... | 0 | Experimental | pubmed | 2,777 | test |
1-hop neighbor's text information: Title: Similar peptides from two beta cell autoantigens, proinsulin and glutamic acid decarboxylase, stimulate T cells of individuals at risk for insulin-dependent diabetes.
Abstract: BACKGROUND: Insulin (1) and glutamic acid decarboxylase (GAD) (2) are both autoantigens in insulin-de... | 1 | Diabetes Mellitus Type 1 | pubmed | 3,999 | test |
1-hop neighbor's text information: Title: Tuberculosis susceptibility of diabetic mice.
Abstract: Increased susceptibility to infections, including tuberculosis (TB), is a major cause of morbidity and mortality in patients with diabetes. Despite the clinical importance of this problem, little is known about how diabete... | 1 | Diabetes Mellitus Type 1 | pubmed | 4,634 | test |
1-hop neighbor's text information: Title: Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy.
Abstract: To reconstruct the mechanisms for the vasoobliteration that transforms diabetic retinopathy into an ischemic retinopathy, we compared the occurrence of cell death in situ ... | 1 | Diabetes Mellitus Type 1 | pubmed | 15,256 | test |
1-hop neighbor's text information: Title: Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
Abstract: Genome-wide association (GWA) studies have identified multiple loci at which common variants modestly but reproducibly influence ri... | 2 | Diabetes Mellitus Type 2 | pubmed | 6,366 | test |
1-hop neighbor's text information: Title: Prevention of severe hypoglycaemia in type I diabetes: a randomised controlled population study.
Abstract: AIMS: To investigate use of targeted self study material in type I diabetes patient education regarding dissemination, perceived patient benefit, and prevention of severe ... | 1 | Diabetes Mellitus Type 1 | pubmed | 10,769 | test |
1-hop neighbor's text information: Title: Insulin action in obese non-insulin-dependent diabetics and in their isolated adipocytes before and after weight loss.
Abstract: To determine the effects of weight loss on insulin action in patients with non-insulin-dependent diabetes mellitus (NIDDM) and in their isolated adip... | 2 | Diabetes Mellitus Type 2 | pubmed | 7,747 | test |
1-hop neighbor's text information: Title: Low plasma C4 concentrations: association with microangiopathy in insulin dependent diabetes.
Abstract: Plasma C4 concentrations were measured in insulin dependent diabetics with and without microangiopathy and in controls. The diabetics had significantly lower C4 values than c... | 1 | Diabetes Mellitus Type 1 | pubmed | 5,143 | test |
1-hop neighbor's text information: Title: Genetic analysis of type 1 diabetes using whole genome approaches.
Abstract: Whole genome linkage analysis of type 1 diabetes using affected sib pair families and semi-automated genotyping and data capture procedures has shown how type 1 diabetes is inherited. A major proportio... | 1 | Diabetes Mellitus Type 1 | pubmed | 9,226 | test |
1-hop neighbor's text information: Title: A review of pioglitazone HCL and glimepiride in the treatment of type 2 diabetes.
Abstract: Type 2 diabetes (T2D) is a progressive disorder with a consistent and steady increase in glycosylated hemoglobin (HbA1c) over time associated with enhanced risk of micro- and macrovascul... | 2 | Diabetes Mellitus Type 2 | pubmed | 16,130 | test |
1-hop neighbor's text information: Title: Effects of the PPARgamma agonist pioglitazone on lipoprotein metabolism in patients with type 2 diabetes mellitus.
Abstract: Elevated plasma levels of VLDL triglycerides (TGs) are characteristic of patients with type 2 diabetes mellitus (T2DM) and are associated with increased ... | 2 | Diabetes Mellitus Type 2 | pubmed | 9,273 | test |
1-hop neighbor's text information: Title: Apoptosis of CD4+ CD25(high) T cells in type 1 diabetes may be partially mediated by IL-2 deprivation.
Abstract: BACKGROUND: Type 1 diabetes (T1D) is a T-cell mediated autoimmune disease targeting the insulin-producing pancreatic beta cells. Naturally occurring FOXP3(+)CD4(+)CD... | 1 | Diabetes Mellitus Type 1 | pubmed | 9,495 | test |
1-hop neighbor's text information: Title: Impact of the individual components of the metabolic syndrome and their different combinations on the prevalence of atherosclerotic vascular disease in type 2 diabetes: the Diabetes in Germany (DIG) study.
Abstract: BACKGROUND: One of the major controversies surrounding the met... | 2 | Diabetes Mellitus Type 2 | pubmed | 14,954 | test |
1-hop neighbor's text information: Title: Prediction of the onset of disturbed eating behavior in adolescent girls with type 1 diabetes.
Abstract: OBJECTIVE: The purpose of this study was to identify predictors of the onset of disturbed eating behavior (DEB) in adolescent girls with type 1 diabetes. RESEARCH DESIGN AND... | 1 | Diabetes Mellitus Type 1 | pubmed | 15,821 | test |
1-hop neighbor's text information: Title: Predictors of health-related quality of life in type II diabetic patients in Greece.
Abstract: BACKGROUND: Diabetes Mellitus (DM) is a major cause of morbidity and mortality affecting millions of people worldwide, while placing a noteworthy strain on public health funding. The ... | 1 | Diabetes Mellitus Type 1 | pubmed | 18,289 | test |
1-hop neighbor's text information: Title: HLA antigens and necrobiosis lipoidica diabeticorum--a comparison between insulin-dependent diabetics with and without necrobiosis.
Abstract: To investigate whether HLA-A, -B, -C, and -DR alloantigen frequencies are different in diabetic patients with and without necrobiosis li... | 1 | Diabetes Mellitus Type 1 | pubmed | 11,820 | test |
1-hop neighbor's text information: Title: Multiple immuno-regulatory defects in type-1 diabetes.
Abstract: Susceptibility to immune-mediated diabetes (IMD) in humans and NOD mice involves their inherently defective T cell immunoregulatory abilities. We have followed natural killer (NK) T cell numbers in patients with I... | 2 | Diabetes Mellitus Type 2 | pubmed | 19,435 | test |
1-hop neighbor's text information: Title: Coffee consumption is associated with higher plasma adiponectin concentrations in women with or without type 2 diabetes: a prospective cohort study.
Abstract: To test whether the beneficial effects of coffee consumption in metabolism might be explained by changes in circulating... | 2 | Diabetes Mellitus Type 2 | pubmed | 18,864 | test |
1-hop neighbor's text information: Title: Blockade of RAGE suppresses periodontitis-associated bone loss in diabetic mice.
Abstract: Diabetes is associated with increased prevalence, severity, and progression of periodontal disease. To test the hypothesis that activation of RAGE (Receptor for Advanced Glycation End pro... | 0 | Experimental | pubmed | 11,830 | test |
1-hop neighbor's text information: Title: Evidence for the association of the SLC22A4 and SLC22A5 genes with type 1 diabetes: a case control study.
Abstract: BACKGROUND: Type 1 diabetes (T1D) is a chronic, autoimmune and multifactorial disease characterized by abnormal metabolism of carbohydrate and fat. Diminished car... | 1 | Diabetes Mellitus Type 1 | pubmed | 2,380 | val |
1-hop neighbor's text information: Title: Effect of diabetes mellitus on response of the basilar artery to activation of ATP-sensitive potassium channels.
Abstract: Our goal was to determine whether responses of the basilar artery to activation of ATP-sensitive potassium channels are altered during diabetes mellitus. W... | 2 | Diabetes Mellitus Type 2 | pubmed | 14,832 | test |
1-hop neighbor's text information: Title: Specific associations of insulin resistance with impaired health-related quality of life in the Hertfordshire Cohort Study.
Abstract: Insulin resistance is a metabolic abnormality that underlies Type 2 diabetes, the metabolic syndrome and cardiovascular disease, but it may also... | 2 | Diabetes Mellitus Type 2 | pubmed | 14,947 | test |
1-hop neighbor's text information: Title: Aminoguanidine prevents arterial stiffening and cardiac hypertrophy in streptozotocin-induced diabetes in rats.
Abstract: The formation of advanced glycation endproducts (AGEs) on collagen within the arterial wall may be responsible for the development of diabetic vascular inju... | 0 | Experimental | pubmed | 4,768 | test |
1-hop neighbor's text information: Title: Current therapeutic options in type 2 diabetes mellitus: a practical approach.
Abstract: The incidence of type 2 diabetes mellitus (DM) in the United States continues to grow rapidly, paralleling the overweight and obesity epidemic. For many years the only therapeutic options f... | 2 | Diabetes Mellitus Type 2 | pubmed | 12,134 | test |
1-hop neighbor's text information: Title: Assessment of insulin action and glucose effectiveness in diabetic and nondiabetic humans.
Abstract: Insulin concentrations in humans continuously change and typically increase only when glucose also increases such as with eating. In this setting, it is not known whether the se... | 2 | Diabetes Mellitus Type 2 | pubmed | 10,845 | test |
1-hop neighbor's text information: Title: Inosine protects against the development of diabetes in multiple-low-dose streptozotocin and nonobese diabetic mouse models of type 1 diabetes.
Abstract: Inosine, a naturally occurring purine, was long considered to be an inactive metabolite of adenosine. However, recently inos... | 0 | Experimental | pubmed | 11,315 | test |
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