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Confronting Covid-19 by exploring the possibility of vaccinating with live SARS-CoV-2 virus itself, via a route that would reduce the incidence of pulmonary complications | This article proposes that one should explore whether the pulmonary complications of Covid-19 can be reduced or avoided by bypassing the airway entry of the SARS-CoV-2 virus. This could possibly be achieved by injecting live SARS-CoV-2 virus intradermal (ID), subcutaneous, intra-muscular (IM) or intra-peritoneal (IP), ... | Please summerize the given abstract to a title |
Review on Dynamics of Offshore Floating Wind Turbine Platforms | This paper presents a literature review of the dynamics of offshore floating wind turbine platforms. When moving further offshore, there is an increase in the capacity of wind power. Generating power from renewable resources is enhanced through the extraction of wind energy from an offshore deep-water wind resource. Mo... | Please summerize the given abstract to a title |
A rare case of macroprolactinoma in a patient with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome. | Summary A 17-year-old lady presented with primary amenorrhoea, headache, nausea and lethargy. She had delayed pubertal development that also includes under-developed breast (Tanner Stage 2). Hormonal investigations showed a high serum prolactin level of 1 680 000 mIU/L (normal value: 45-375 mIU/L), with low oestradiol,... | Please summerize the given abstract to a title |
Distinct Immune Response at 1 Year Post-COVID-19 According to Disease Severity | BACKGROUND: Despite the fact of ongoing worldwide vaccination programs for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), understanding longevity, breadth, and type of immune response to coronavirus disease-19 (COVID-19) is still important to optimize the vaccination strategy and estimate the risk of rei... | Please summerize the given abstract to a title |
Critically Ill Patients with Middle East Respiratory Syndrome Coronavirus Infection | The Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging virus that may lead to severe acute respiratory illness frequently associated with multiorgan failure and death. The objective of this chapter is to summarize the current state of knowledge regarding the pathogenesis, clinical manifestations, di... | Please summerize the given abstract to a title |
Design Performance and Frequency Response Analysis of SAW-Based Sensor for Dichloromethane Gas Sensing Amidst the COVID-19 | BACKGROUND: To avoid the risk of increase in the rate of human infection is a big challenge for healthcare staffs during the treatment of patients affected from corona virus disease-2019 (COVID-19). This work is intended to save COVID-19-infected patients from conveyed hazardous volatile gases (VOCs) by the gas stream.... | Please summerize the given abstract to a title |
A60 Revealing the evolution of virulence in RNA viruses | A combination of high rates of mutation and replication, coupled with strong natural selection, ensures that RNA viruses experience rapid genotypic and phenotypic evolution. Such a ‘fast-forward’ evolution enables viruses to rapidly adapt to new host species, evade host immune responses, and to develop resistance to an... | Please summerize the given abstract to a title |
It's a (vital) Sign: How Post-covidien Interagency Collaboration Can Prevent Future Medical Device Shortages | I feel like I'm trying to ventilate bricks instead of lungs," remarked one intensive care unit physician who has been treating COVID-19 patients for the last several months. The change in lung texture encountered by practitioners handling severe COVID-19 cases is caused by a potentially lethal presentation of acute res... | Please summerize the given abstract to a title |
COVID-19 Lockdown Measures: Impact On Older Adults With Dementia And Their Caregivers In Singapore | Family caregivers typically rely on community-based services and social support networks to supplement their caregiving of older adults with dementia (OAwD). In April 2020, the Singapore government implemented a partial lockdown to contain the spread of COVID-19. We assessed the policy's impact on the physical and ment... | Please summerize the given abstract to a title |
Taking a Health Perspective on Roller Derby: A Qualitative Exploration of Women’s Experiences | Although far fewer women exercise regularly than men, one women-dominated sport growing in popularity internationally is roller derby. A limited number of predominantly US-based and qualitative studies have explored roller derby. This Scotland-based qualitative study explored reasons for women starting, continuing, and... | Please summerize the given abstract to a title |
Central Nervous System Manifestations of COVID-19: A Critical Review and Proposed Research Agenda. | OBJECTIVE On March 11, 2020, the World Health Organization declared an outbreak of a new viral entity, coronavirus 2019 (COVID-19), to be a worldwide pandemic. The characteristics of this virus, as well as its short- and long-term implications, are not yet well understood. The objective of the current paper was to prov... | Please summerize the given abstract to a title |
Teachers in COVID-19 period: Psychological effects, practices and career needs | The purpose of the current study was to examine teachers' career needs and psychosocial experience during the COVID-19 pandemic within the phenomenological pattern of qualitative research methods. The data collection process included individual interviews and an online survey form. As a result of the research, four mai... | Please summerize the given abstract to a title |
ADHD symptoms in relation to depressive and sleep-related symptoms among university students during the COVID-19 outbreak in Japan | Background: The COVID-19 pandemic and its associated societal response are anticipated to have wide-ranging effects on youth development and mental health. The three most common mental health problems among university students are depression, anxiety, and attention-deficit hyperactivity disorder (ADHD). Many factors th... | Please summerize the given abstract to a title |
Influence of recent administration and type of oncological treatment (T) in survival of oncological patients (p) with COVID-19: Experience of Vall d'Hebron University Hospital | Background: SARS-CoV-2 outbreak has impacted on the management of oncological p, leading to treatment delays in a considerable number of cases The aim of this study was to evaluate if oncological T affected negatively COVID-19 outcome Methods: We retrospectively analyzed clinical data from p with solid tumors under act... | Please summerize the given abstract to a title |
COVID-19: Fear of pandemic and short-term IPO performance | This study analyzes the relationship between COVID-19 related fear and short-term IPO performance. Though the average market-adjusted initial return of IPOs in the year 2020 is higher than that of the last four decades, it decreases if fear of pandemic increases. The evidence is robust when we use matching firm-adjuste... | Please summerize the given abstract to a title |
A New Assessment of Bicycle Helmets: The Brain Injury Mitigation Effects of New Technologies in Oblique Impacts | New helmet technologies have been developed to improve the mitigation of traumatic brain injury (TBI) in bicycle accidents. However, their effectiveness under oblique impacts, which produce more strains in the brain in comparison with vertical impacts adopted by helmet standards, is still unclear. Here we used a new me... | Please summerize the given abstract to a title |
A Study of Dignity as a Principle of Service Design | This paper upholds the premise that dignity is a fundamental principle of human-centered design. I argue that consideration of dignity is particularly important in service design, as service concerns the collective participation of people with diverse backgrounds and needs. Service often starts with situations in which... | Please summerize the given abstract to a title |
Does healthcare system device volume correlate with price paid for spinal implants: a cross-sectional analysis of a national purchasing database | OBJECTIVES: Amid continuously rising US healthcare costs, particularly for inpatient and surgical services, strategies to more effectively manage supply chain expenses are urgently necessary. Across industries, the ‘economy of scale’ principle indicates that larger purchasing volumes should correspond to lower prices d... | Please summerize the given abstract to a title |
Identification and prediction of time-varying parameters of COVID-19 model: a data-driven deep learning approach | Data-driven deep learning provides efficient algorithms for parameter identification of epidemiology models. Unlike the constant parameters, the complexity of identifying time-varying parameters is largely increased. In this paper, a variant of physics-informed neural network is adopted to identify the time-varying par... | Please summerize the given abstract to a title |
Aspiration thrombectomy in ST-Elevation myocardial infarction: Further insights from a network meta-analysis of randomized trials | BACKGROUND: The initial enthusiasm for thrombectomy during percutaneous coronary intervention (PCI) of ST-elevation myocardial infarction (STEMI) patients has given way to restraint. There has been some limited interest whether it is beneficial in a few selected subgroups. Hence, we performed a network meta-analysis to... | Please summerize the given abstract to a title |
Creating healthful cultures through Critical Creativity: Working with the body senses, reflection, connection with Nature, ancient wisdom & creative imagination | During Covid lockdown in 2021, I was invited to offer a masterclass to masters students at Queen Margaret University, Edinburgh: 'In the leadership module we have a masterclass, groupwork, study time and a plenary that ties together. We even have a book club!!! The aim is to be generic, not nursing/health focused. The ... | Please summerize the given abstract to a title |
Staphylococcus aureus Bacteremia in Patients Infected With COVID-19: A Case Series | Background: Previous viral pandemics have shown that secondary bacterial infections result in higher morbidity and mortality, with Staphylococcus aureus being the primary causative pathogen. The impact of secondary S. aureus bacteremia on mortality in patients infected with severe acute respiratory syndrome coronavirus... | Please summerize the given abstract to a title |
Targeting the CCL2/CCR2 Axis in Cancer Immunotherapy: One Stone, Three Birds? | CCR2 is predominantly expressed by monocytes/macrophages with strong proinflammatory functions, prompting the development of CCR2 antagonists to dampen unwanted immune responses in inflammatory and autoimmune diseases. Paradoxically, CCR2-expressing monocytes/macrophages, particularly in tumor microenvironments, can be... | Please summerize the given abstract to a title |
Score-Level Fusion of 3D Face and 3D Ear for Multimodal Biometric Human Recognition | A novel multimodal biometric system is proposed using three-dimensional (3D) face and ear for human recognition. The proposed model overcomes the drawbacks of unimodal biometric systems and solves the 2D biometric problems such as occlusion and illumination. In the proposed model, initially, the principal component ana... | Please summerize the given abstract to a title |
Factors Related to Non-compliance With Non-pharmaceutical Interventions to Mitigate the Spread of SARS-CoV-2: Results From a Survey in the Swiss General Adult Population | BACKGROUND: Non-pharmaceutical interventions (NPI) play an important role in national efforts to control and contain the spread of SARS-CoV-2, but some people do not comply with these public health measures. The aim of this study was thus to describe this group of noncompliant people. METHODS: A random sample of 1,157 ... | Please summerize the given abstract to a title |
COVID-19 gender susceptibility and outcomes: A systematic review | BACKGROUND: Epidemiological differences between men and women have been reported with regards to sepsis, influenza and severe coronavirus infections including SARS-CoV and MERS-CoV. AIM: To systematically review the literature relating to men versus women on SARS-CoV-2 in order to seek differences in disease characteri... | Please summerize the given abstract to a title |
COVID-19 Stress and Mental Health of Students in Locked-Down Colleges | The impact of the COVID-19 pandemic on the mental health of students in locked-down colleges remains obscure. This study aimed to explore influencing factors for the psychological impact of COVID-19 on Wuhan college students, post-traumatic stress symptoms in particular, so as to inform evidence-based strategy developm... | Please summerize the given abstract to a title |
Mask use among pedestrians during the Covid-19 pandemic in Southwest Iran: an observational study on 10,440 people | BACKGROUND: Many countries have recommended the use of face masks for general population in public places to reduce the risk of COVID-19 transmission. This study aims to estimate the prevalence of face mask usage and investigate about different types of face mask and their distribution among pedestrians in southwest Ir... | Please summerize the given abstract to a title |
Covid-19: Do Medical Students Know, Bother About, and Practise Preventive Measures in Malaysia? | Since December 2019, a novel coronavirus disease (COVID-19) creates a global threat Medical students are more susceptible to be infected by the virus This study aimed to assess COVID-19 related knowledge, attitude towards COVID-19, and preventive behaviours against COVID-19 among medical students within the first month... | Please summerize the given abstract to a title |
Clinical Characteristics and Short-Term Outcomes of Chronic Dialysis Patients Admitted for COVID-19 in Metro Manila, Philippines | AIM: Data published on COVID-19 in the Filipino population, particularly those with end stage kidney disease (ESKD) are still lacking. METHODS: We performed a retrospective, observational study of 68 ESKD patients admitted with COVID-19 infection at a tertiary hospital in Metro Manila, Philippines from April 1, 2020 to... | Please summerize the given abstract to a title |
Differences between COVID-19 and suspected then confirmed SARS-CoV-2-negative pneumonia: A retrospective study from a single center | Coronavirus disease 2019 (COVID-19) broke out in Wuhan, Hubei, China in December 2019. Tens thousands of people have been infected with the disease. Our aim was to distinguish severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive patients from SARS-CoV-2-negative patients. We retrospectively compared th... | Please summerize the given abstract to a title |
Challenges Faced by Nursing Home Direct Care Workers During the COVID-19 Pandemic: A Comparison Across Care Settings | The COVID-19 pandemic has generated awareness of the value of the direct care workforce to provide care in settings serving those most at risk from the disease. However, few studies have gauged the impact of COVID-19 on this workforce and their pandemic-related challenges. The purpose of this study was to examine the c... | Please summerize the given abstract to a title |
The two-year deadline to complete the International Seabed Authority’s Mining Code: Key outstanding matters that still need to be resolved | The International Seabed Authority (ISA) is an autonomous international organization established under the UN Convention on the Law of the Sea 1982 (UNCLOS) to organize and control the exploration for and exploitation of seabed mineral resources in areas beyond the limits of national jurisdiction. A system for explorat... | Please summerize the given abstract to a title |
The future of non-financial businesses reporting: Learning from the Covid-19 pandemic | Abstract In this paper we conceptually identify the gap in the literature about lack of business's awareness in non -financial activities, especially biodiversity, which can be responsible for crisis like Covid-19 which can adversely affect the global economy We recommend approaches to existing business about how to en... | Please summerize the given abstract to a title |
The Gravitational Bending of Acoustic Schwarzschild Black Hole | Acoustic black hole is becoming an attractive topic in recent years, for it open-up new direction for experimental explorations of black holes. In this work, the gravitational bending of acoustic Schwarzschild black hole is investigated. The gravitational deflection angle of particles traveling along null geodesics, we... | Please summerize the given abstract to a title |
Rates of Acute Myocardial Infarction During the COVID-19 Pandemic | BACKGROUND: During the early phases of the COVID-19 pandemic pandemic, stay-at-home orders and fear of acquiring COVID-19 may have led to an avoidance of care for medical emergencies, including acute myocardial infarction (AMI). We evaluated whether a decline in rates of AMI occurred during the COVID-19 stay-at-home or... | Please summerize the given abstract to a title |
A Review of the Current Status of Clinical Management of COVID-19 in the Elderly | The high infectivity and severity of SARS-CoV-2 infection (COVID-19), and our limited understanding of the biology of the novel coronavirus, as well as the lack of an effective treatment for COVID-19, have created a global pandemic. Those most likely to become seriously ill with COVID-19 are adults, especially the elde... | Please summerize the given abstract to a title |
Stay-at-home orders, social distancing, and trust | A clear understanding of community response to government decisions is crucial for policy makers and health officials during the COVID-19 pandemic. In this study, we document the determinants of implementation and compliance with stay-at-home orders in the USA, focusing on trust and social capital. Using cell phone dat... | Please summerize the given abstract to a title |
Monitoring Re-Growth of Invasive Plants Using an Autonomous Surface Vessel | Invasive aquatic plant species, and in particular Eurasian Water-Milfoil (EWM), pose a major threat to domestic flora and fauna and can in turn negatively impact local economies. Numerous strategies have been developed to harvest and remove these plant species from the environment. However it is still an open question ... | Please summerize the given abstract to a title |
Heart Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 Gene Expression Associated With Male Sex and Salt-Sensitive Hypertension in the Dahl Rat | Angiotensin-converting enzyme 2 (ACE 2) in the heart including its sex dependency in the hypertensive heart, has not been much studied compared to ACE. In the present study, we used the Dahl salt-sensitive rat exposed to fructose and salt to model a hypertensive phenotype in males, females, and ovariectomized females. ... | Please summerize the given abstract to a title |
Optimal Control of a SIR Epidemic With ICU Constraints and Target Objectives | The aim of this paper is to provide a rigorous mathematical analysis of an optimal control problem with SIR dynamics. The main feature of our study is the presence of state constraints (related to intensive care units ICU capacity) and strict target objectives (related to the immunity threshold). The first class of res... | Please summerize the given abstract to a title |
Proven COVID‐19—associated pulmonary aspergillosis in patients with severe respiratory failure | BACKGROUND: An increasing number of reports have described the COVID‐19–associated pulmonary aspergillosis (CAPA) as being a further contributing factor to mortality. Based on a recent consensus statement supported by international medical mycology societies, it has been proposed to define CAPA as possible, probable, o... | Please summerize the given abstract to a title |
Causal Associations Between Blood Lipids and COVID-19 Risk: A Two-Sample Mendelian Randomization Study | OBJECTIVE: Coronavirus disease 2019 (COVID-19) is a global pandemic caused by the severe acute respiratory syndrome coronavirus 2. It has been reported that dyslipidemia is correlated with COVID-19, and blood lipids levels, including total cholesterol, HDL-C (high-density lipoprotein cholesterol), and LDL-C (low-densit... | Please summerize the given abstract to a title |
Uniting for adolescents in covid-19 and beyond | Adolescents and young adults are also experiencing a crisis of connection to family, community, and society, with increasing numbers living on the streets or dropping out of school 34 Between 2003 and 2015, development assistance for adolescent health accounted for only 1 6% of total development assistance for health,5... | Please summerize the given abstract to a title |
Augmented reality is human-like: How the humanizing experience inspires destination brand love | Drawing on humanizing experience theory, we examined the antecedents and consequences of humanizing the digital experience in a virtual tourism context. Using a scenario survey approach, we designed dynamic 360° augmented reality (AR) panorama and 360° spin-of-the-mouse environments to examine the research model and hy... | Please summerize the given abstract to a title |
Childhood Immunization and COVID-19: An Early Narrative Review | The COVID-19 pandemic has evolved into arguably the largest global public health crisis in recent history—especially in the absence of a safe and effective vaccine or an effective anti-viral treatment. As reported, the virus seems to less commonly infect children and causing less severe symptoms among infected children... | Please summerize the given abstract to a title |
COVID-19 induced ischemic stroke and mechanisms of viral entry in brain and clot formation: a systematic review and current update | Background: Coronavirus disease 2019, caused by SARS-CoV-2 (SCV-2) was stated as a pandemic on March 11 2020 by World Health Organization (WHO), and since then, it has become a major health issue worldwide. It mainly attacks the respiratory system with various accompanying complications, including cardiac injury, renal... | Please summerize the given abstract to a title |
Depressive symptoms in helping professions: a systematic review of prevalence rates and work-related risk factors | OBJECTIVE: The aim of this study is twofold. Our first aim is to provide an overview of the prevalence rate of depression in a wide array of helping professions. Our second aim is to identify work organization conditions that seem to be associated with this depression risk. METHODS: Four databases were searched (CINAHL... | Please summerize the given abstract to a title |
How leaders can manage the disruption caused by the pandemic (preprint)/ en | Organisations have over time adopted conservative, structured and controlled processes to manage and achieve goals set with their stakeholders. Contrary to that, an environment of disruption has emerged, that being a faster, less predictable and less certain environment than the previous fifty or more years. This envir... | Please summerize the given abstract to a title |
Epidemiological And Clinical Characteristics of The First 18 Patients with COVID-19 in Taiwan | To understand the epidemiological and clinical characteristics of patients with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in Taiwan, we analyzed data from the National Notifiable Disease Surveillance System and epidemiological case investigation reports We included all real-time reverse-tra... | Please summerize the given abstract to a title |
Performance of Three Measures of Comorbidity in Predicting Critical COVID-19: A Retrospective Analysis of 4607 Hospitalized Patients | BACKGROUND: Comorbidity burden has been identified as a relevant predictor of critical illness in patients hospitalized with coronavirus disease 2019 (COVID-19). However, comorbidity burden is often represented by a simple count of few conditions that may not fully capture patients’ complexity. PURPOSE: To evaluate the... | Please summerize the given abstract to a title |
Pre-vaccination frequency of circulatory Tfh is associated with robust immune response to TV003 dengue vaccine | It has been estimated that more than 390 million people are infected with Dengue virus every year; around 96 millions of these infections result in clinical pathologies. To date, there is only one licensed viral vector-based Dengue virus vaccine CYD-TDV approved for use in dengue endemic areas. While initially approved... | Please summerize the given abstract to a title |
The xenophobia virus and the COVID-19 pandemic | Summary The text addresses the risks involving xenophobia against the Chinese on the internet, and social networks, from the COVID-19 pandemic, in addition to demonstrating how irrational this manifestation is, especially the idea of virus creation in a laboratory For this purpose, historical examples of how xenophobic... | Please summerize the given abstract to a title |
Case Report: Importance of MRI Examination in the Diagnosis and Evaluation of COVID-19 mRNA Vaccination Induced Myocarditis: Our Experience and Literature Review | Acute myocarditis is a rare but serious complication associated with mRNA-based coronavirus disease 2019 (COVID-19) vaccination. In this article, four COVID-19 mRNA vaccination induced myocarditis cases managed at our tertiary Medical Center have been discussed. Three patients had typical myocarditis. One patient suffe... | Please summerize the given abstract to a title |
Psychological reactance and beliefs in conspiracy theories during the COVID-19 pandemic: Overview of the extended parallel process model (EPPM) | Compliance with health protocols plays an important role in minimizing the spread of COVID-19. However, Indonesia is still facing a robust challenge including non-compliance to persuasive recommendations or messages (psychological reactance) and belief in conspiracy theories. Issues related to conspiracy theories and t... | Please summerize the given abstract to a title |
Clinical and economic benefits of lenzilumab plus standard of care compared with standard of care alone for the treatment of hospitalized patients with Coronavirus Disease 19 (COVID-19) from the perspective of National Health Service England | Purpose: Estimate the clinical and economic benefits of lenzilumab plus standard of care (SOC) compared with SOC alone in the treatment of hospitalized COVID-19 patients from the National Health Service (NHS) England perspective. Methods: A cost calculator was developed to estimate the clinical benefits and costs of ad... | Please summerize the given abstract to a title |
What strategies are countries using to expand health workforce surge capacity during the COVID-19 pandemic? (Special Issue: COVID-19 health system response.) | Finding ways to increase the surge capacity and flexibility of the health workforce has been fundamental to delivering an effective COVID-19 response This article explores the strategies that 44 countries in Europe plus Canada have taken to maintain and increase the availability of health workers using data from the CO... | Please summerize the given abstract to a title |
Feasibility of community health workers as teleaudiology patient-site facilitators: a multilevel training study. | OBJECTIVE We evaluated the feasibility of a multi-level teleaudiology patient-site facilitator training program for Community Health Workers (CHWs) at a partnering health centre in southern Arizona. DESIGN Three levels were offered: Introductory, with basic information on hearing loss and teleaudiology; Intermediate, o... | Please summerize the given abstract to a title |
American Frontline Healthcare Personnel's Access to and Use of Personal Protective Equipment Early in the COVID-19 Pandemic | To quantify adequacy of personal protective equipment (PPE) for U.S. healthcare personnel (HCP) at the outset of the COVID-19 pandemic and its association with infection risk. METHODS: March–May 2020 survey of the national Nurses’ Health Studies and the Growing Up Today study regarding self-reported PPE access, use, an... | Please summerize the given abstract to a title |
Ventilation management and clinical outcomes in invasively ventilated patients with COVID-19 (PRoVENT-COVID): a national, multicentre, observational cohort study | BACKGROUND: Little is known about the practice of ventilation management in patients with COVID-19. We aimed to describe the practice of ventilation management and to establish outcomes in invasively ventilated patients with COVID-19 in a single country during the first month of the outbreak. METHODS: PRoVENT-COVID is ... | Please summerize the given abstract to a title |
Development of new SNP genotyping assays to discriminate the Omicron variant of SARS-CoV-2. | The World Health Organization (WHO) designated Omicron (B.1.1.529 lineage) of SARS-CoV-2 as a new variant of concern (VOC) on 26th of November 2021. The risk to public health conferred by the Omicron variant is still not completely clear, although its numerous gene mutations raise concern about its potential for increa... | Please summerize the given abstract to a title |
Infektionen | Die Meldung und Erfassung von Infektionskrankheiten ist in Deutschland durch das Infektionsschutzgesetz (IfSG) geregelt. In §6 sind meldepflichtige Krankheiten nach gewissen Vorgaben geregelt. | Please summerize the given abstract to a title |
The COVID-19 pandemic and paradigm change in global scientific research | The current pandemic has rocked the lives of human beings everywhere in ways never imagined, forcing us to question where our civilization is headed. In this article, we explore and discuss scientific evidence that helps explain recent events in the context of the COVID-19 pandemic. COVID-19 is caused by infection with... | Please summerize the given abstract to a title |
Targeting S1PR1 May Result in Enhanced Migration of Cancer Cells in Bladder Carcinoma | SIMPLE SUMMARY: Metastasis is critical to the prognosis of patients with bladder cancer, and it is important to understand the mechanism of its occurrence. S1PR1 expression is thought to be associated with poor prognosis, but it is unknown whether it is associated with tumor metastasis. Analysis of clinical gene expres... | Please summerize the given abstract to a title |
Infection, Sepsis and the Inflammatory Response: Mechanisms and Therapy | Sepsis secondary to bacterial infection remains a significant cause of morbidity and mortality globally. Recent decades have seen the evolution of international collaborations to improve care for these patients and identify areas for research. In this article we discuss the pathophysiology underlying the condition, rev... | Please summerize the given abstract to a title |
Saving the Diabetic Foot During the COVID-19 Pandemic: A Tale of Two Cities | Of all the late complications of diabetes, those involving the foot have traditionally required more face-to-face patient visits to clinics to treat wounds by debridement, offloading, and many other treatment modalities. The advent of the coronavirus disease 2019 (COVID-19) pandemic has resulted not only in the closing... | Please summerize the given abstract to a title |
Radiological Findings of COVID-19 in Children: A Systematic Review and Meta-Analysis | BACKGROUND: The majority of the children with SARS-CoV-2 infection present with respiratory symptoms, hence various chest imaging modalities have been used in the management. Knowledge about the radiological findings of coronavirus disease (COVID-19) in children is limited. Hence, we systematically synthesized the avai... | Please summerize the given abstract to a title |
Targeting Neutrophils Extracellular Traps (NETs) reduces multiple organ injury in a COVID-19 mouse model | COVID-19 is characterized by severe acute lung injury, which is associated with neutrophils infiltration and release of neutrophil extracellular traps (NETs). COVID-19 treatment options are scarce. Previous work has shown an increase in NETs release in the lung and plasma of COVID-19 patients suggesting that drugs that... | Please summerize the given abstract to a title |
Avoidance of oxidative‐stress perturbation in yeast bioprocesses by proteomic and genomic biostrategies? | Aims: Bioprocess oxidative stress caused by many reactive oxygen species (ROS) can lead to largely irreversible perturbation of yeast bioprocesses. These include the production of proteins derived from recombinant DNA yeast technology (aerobically grown Saccharomyces cerevisiae). These proteins include rennin, amyloglu... | Please summerize the given abstract to a title |
Nitrogen dioxide reductions from satellite and surface observations during COVID-19 mitigation in Rome (Italy) | Lockdown restrictions were implemented in Italy from 10 March 2020 to contain the COVID-19 pandemic. Our study aims to evaluate air pollution changes, with focus on nitrogen dioxide (NO2), before and during the lockdown in Rome and in the surroundings. Significant NO2 declines were observed during the COVID-19 pandemic... | Please summerize the given abstract to a title |
Condiciones médicas, síntomas de ansiedad y depresión durante la pandemia por COVID-19 en una muestra poblacional de Lima, Perú | Introducción: El objetivo de este estudio es determinar diferencias entre el número de condiciones médicas subyacentes, depresión y ansiedad, al controlar por las covariables edad, sexo y educación completa. Métodos: Los participantes (n = 484) indicaron el número de condiciones médicas presentes durante la encuesta, i... | Please summerize the given abstract to a title |
The Art of Prevention: COVID-19 Vaccine Preparedness for the Dermatologist | As COVID-19 vaccinations begin, dermatologists must be aware of the cutaneous adverse events reported in the clinical trials, including injection site and hypersensitivity reactions, and emerging evidence of dermal filler injection reactions following vaccination. The filler reaction may represent development of a dela... | Please summerize the given abstract to a title |
Preterm Infant Outcomes Following COVID-19 Lockdowns in Melbourne, Australia | Background Community lockdowns during the coronavirus disease 2019 (COVID-19) pandemic may influence preterm birth rates, but mechanisms are unclear. Methods We compared neonatal outcomes of preterm infants born to mothers exposed to community lockdowns in 2020 (exposed group) to those born in 2019 (control group). Mai... | Please summerize the given abstract to a title |
Internet-of-Things Devices and Assistive Technologies for Healthcare: Applications, Challenges, and Opportunities | Medical conditions and cases are growing at a rapid pace, where physical space is starting to be constrained. Hospitals and clinics no longer have the ability to accommodate large numbers of incoming patients. It is clear that the current state of the health industry needs to improve its valuable and limited resources.... | Please summerize the given abstract to a title |
Psychological distress in healthcare workers during COVID-19 pandemic | With the sudden outbreak of coronavirus disease of 2019 (COVID-19) pandemic, the Health Care Workers (HCWs) have claimed varying echelons of stress, anxiety and insomnia This is the first write up ever reported describing the numerous studies conducted globally to determine the mental health issues in HCWs throughout i... | Please summerize the given abstract to a title |
Japan's public health and culture, and the ongoing fight against COVID-19. (Special Issue: COVID-19: conventional therapies, fates, and mechanisms.) | The rising number of new cases or new waves of COVID-19 infections threaten to overwhelm or collapse the health care system in many countries The pandemic is likely to make the human sufferings worse However, unlike many other developed countries, the situation in Japan with respect to COVID-19 remains relatively very ... | Please summerize the given abstract to a title |
COVID-19: a qualitative chest CT model to identify severe form of the disease | Purpose – The purpose of this study was to identify clinical and chest computed tomography (CT) features associated with a severe form of coronavirus disease 2019 (COVID-19) and to propose a quick and easy to use model to identify patients at risk of a severe form. Materials and Methods – A total of 158 patients with b... | Please summerize the given abstract to a title |
Metformin therapy, severity and mortality of SARS-CoV-2 infection: A meta-analysis | Background. It has been postulated that metformin could have anti-SARS-CoV-2 action. This raises the hypothesis that people who take metformin may have lower SARS-CoV-2 severity and/or mortality. Objectives. To conduct a meta-analysis of the association between the use of Metformin and risk of severity and mortality in... | Please summerize the given abstract to a title |
Mechanism of the different metabolome responses between Plutella xylostella and Pieris rapae treated with the diamide insecticides. | Diamide insecticides, such as chlorantraniliprole, cyantraniliprole, and tetrachlorantraniliprole, are a new class of insecticides that selectively target insects by affecting calcium homeostasis. While this class of insecticides are effective on a wide range of insect pests, the toxicities of diamide insecticides vary... | Please summerize the given abstract to a title |
A history of biological disasters of animal origin in North America. | This paper examines past occurrences in North America relevant to the possibility of biological disasters with animal origins. With respect to naturally occurring animal disease outbreaks, North America, while not as adversely affected by epizootics as other regions, has had its fair share of such outbreaks of both 'tr... | Please summerize the given abstract to a title |
Supratherapeutic lithium levels in COVID‐19 infection | Lithium levels are often checked in the inpatient setting when a patient has clear indications of acute kidney injury. Lithium levels can become supratherapeutic in COVID‐19 infection even after normalization of creatinine. Lithium levels should be checked routinely in patients with COVID‐19 infection in order to avoid... | Please summerize the given abstract to a title |
COVID-19 pandemic and potential of artificial intelligence. | OBJECTIVE To evaluate the potential of artificial intelligence in combating COVID-19 pandemic. METHODS PubMed, Embase, Cochrane Library and Google Scholar were searched for the term "Artificial intelligence and COVID-19" up to March 31, 2021. RESULTS Artificial intelligence (AI) is a potential tool to contain the curre... | Please summerize the given abstract to a title |
Conceptualizing Cybersecurity Management Impact on Performance: Agility and Information Technology Governance | It is inevitable that the era of Industrial Revolution 4.0 is here, businesses are digitalizing their processes especially under the uncertainty inflicted by the COVID-19 pandemic to stay competitive. However, businesses and governing agencies soon realizes the potential pitfall of excessive digitalization without addr... | Please summerize the given abstract to a title |
Symptoms and immunoglobulin development in hospital staff exposed to a SARS-CoV-2 outbreak | BACKGROUND: Worldwide, the number of SARS-CoV-2 infections is increasing. Serological immunoglobulin tests may help to better understand the development of immune mechanisms against SARS-CoV-2 in COVID-19 cases and exposed but asymptomatic individuals. The aim of this study was to investigate exposure to SARS-CoV-2, sy... | Please summerize the given abstract to a title |
An Exploration of Geo-temporal Characteristics of Users' Reactions on Social Media During the Pandemic | During the outbreak of the COVID-19 pandemic, social networks become the preeminent medium for communication, social discussion, and entertainment. Social network users are regularly expressing their opinions about the impacts of the coronavirus pandemic. Therefore, social networks serve as a reliable source for studyi... | Please summerize the given abstract to a title |
Impact of operator experience on transcranial magnetic stimulation | OBJECTIVE: To determine the impact of an operator’s experience on transcranial magnetic stimulation (TMS) measurement. METHODS: Operator B (beginner), operator E (expert), and 30 healthy participants joined the study consisting of two experiments. In each experiment, each operator performed a TMS protocol on each parti... | Please summerize the given abstract to a title |
An mRNA-based vaccine candidate against SARS-CoV-2 elicits stable immuno-response with single dose | D614G genotype of SARS-CoV-2 virus is highly infectious and responsible for almost all infection for 2nd wave. However, there are currently no reports with D614G as vaccine candidate. Here we report the development of an mRNA-LNP vaccine with D614G variant and characterization in animal model. We have used special mRNA... | Please summerize the given abstract to a title |
Blood neurofilament light chain and total tau levels at admission predict death in COVID-19 patients | BACKGROUND AND AIMS: Patients infected with SARS-CoV-2 range from asymptomatic, to mild, moderate or severe disease evolution including fatal outcome. Thus, early predictors of clinical outcome are highly needed. We investigated markers of neural tissue damage as a possible early sign of multisystem involvement to asse... | Please summerize the given abstract to a title |
Machine learning to assist clinical decision-making during the COVID-19 pandemic | BACKGROUND: The number of cases from the coronavirus disease 2019 (COVID-19) global pandemic has overwhelmed existing medical facilities and forced clinicians, patients, and families to make pivotal decisions with limited time and information. MAIN BODY: While machine learning (ML) methods have been previously used to ... | Please summerize the given abstract to a title |
A Social Media Microinfluencer Intervention to Reduce COVID-19 Vaccine Hesitancy in Underserved Tennessee Communities: A Protocol Paper | Background Central to effective public health policy and practice is the trust between the population served and the governmental body leading health efforts, but that trust has eroded in the years preceding the pandemic. Vaccine hesitancy among adults is also a growing concern across the US. Recent data suggests that ... | Please summerize the given abstract to a title |
Recognition and management of depression in early psychosis. | AIMS AND METHOD Depression in first-episode psychosis (FEP) is highly prevalent and associated with poor outcomes; it has become increasingly recognised and adopted in national and international guidelines for psychosis. Using a 26-item questionnaire, this study aimed to explore if this shift has led to greater recogni... | Please summerize the given abstract to a title |
Modeling Reactive Species Metabolism in Colorectal Cancer for Identifying Metabolic Targets and Devising Therapeutics | Reactive species (RS) are known to play significant roles in cancer development as well as in treating or managing cancer. On the other hand, genome scale metabolic models are being used to understand cell metabolism in disease contexts including cancer, and also in planning strategies to handle diseases. Despite their... | Please summerize the given abstract to a title |
High-Throughput Activity Assay for Screening Inhibitors of the SARS-CoV-2 Mac1 Macrodomain | [Image: see text] Macrodomains are a class of conserved ADP-ribosylhydrolases expressed by viruses of pandemic concern, including coronaviruses and alphaviruses. Viral macrodomains are critical for replication and virus-induced pathogenesis; therefore, these enzymes are a promising target for antiviral therapy. However... | Please summerize the given abstract to a title |
Psychological and mental health impacts of COVID-19 pandemic on healthcare workers in China: A review | The coronavirus disease-19 (COVID-19) pandemic has put healthcare workers in an unprecedented situation, increasing their psychological and mental health distress. Much research has focused on the issues surrounding anxiety, depression, and stress among healthcare workers. The consequences of mental health problems on ... | Please summerize the given abstract to a title |
Preferences for Medical Consultations from Online Providers: Evidence from a Discrete Choice Experiment in the United Kingdom | BACKGROUND: In the UK, consultations for prescription medicines are available via private providers such as online pharmacies. However, these providers may have lower thresholds for prescribing certain drugs. This is a particular concern for antibiotics, given the increasing burden of antimicrobial resistance. Public p... | Please summerize the given abstract to a title |
Clinical and Epidemiological Characteristics of COVID-19 Mortality in Saudi Arabia: A Retrospective Multi-Center Study | Background: Coronavirus disease 2019 (COVID-19) has resulted in considerable morbidity and mortality worldwide since December 2019. This study highlights the significant burden of the COVID-19 outbreak, particularly in patients’ health and the healthcare system. This study's clinical implication provides insight into t... | Please summerize the given abstract to a title |
Dementia and Major Neurocognitive Disorders: Some Lessons Learned One Century after the first Alois Alzheimer’s Clinical Notes | Over 100 years ago, Alois Alzheimer presented the clinical signs and symptoms of what has been later called "Alzheimer Dementia" in a young woman whose name was Augustine Deter [...]. | Please summerize the given abstract to a title |
How to strengthen a health research system: WHO's review, whose literature and who is providing leadership? | BACKGROUND: Health research is important for the achievement of the Sustainable Development Goals. However, there are many challenges facing health research, including securing sufficient funds, building capacity, producing research findings and using both local and global evidence, and avoiding waste. A WHO initiative... | Please summerize the given abstract to a title |
A Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis. | BACKGROUND Antibiotic therapy has been proposed as an alternative to surgery for the treatment of appendicitis. METHODS We conducted a pragmatic, nonblinded, noninferiority, randomized trial comparing antibiotic therapy (10-day course) with appendectomy in patients with appendicitis at 25 U.S. centers. The primary outc... | Please summerize the given abstract to a title |
SP2-3 The impact of the COVID-19 global pandemic on oncology drug development, clinical research and R&D in Japan | The challenges due to the impact of the coronavirus disease 2019 (COVID-19) pandemic and the unprecedented public health crisis are severely affecting oncology clinical trials, early to late phase drug development and clinical research. There has been a decrease in the numbers of new trial initiations, site activations... | Please summerize the given abstract to a title |
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