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metadata
license: cc-by-nc-4.0
dataset_info:
  features:
    - name: graph_data
      struct:
        - name: edge_attr
          sequence:
            sequence: int64
        - name: edge_index
          sequence:
            sequence: int64
        - name: pos
          sequence:
            sequence: float64
        - name: solvent_class
          dtype: int64
        - name: x
          sequence:
            sequence: float64
    - name: c_peaks
      sequence:
        sequence: float64
    - name: h_peaks
      sequence:
        sequence: float64
    - name: filename
      dtype: string
  splits:
    - name: train
      num_bytes: 176931469
      num_examples: 21869
    - name: eval
      num_bytes: 3856453
      num_examples: 479
    - name: eval_zeroshot
      num_bytes: 1528168
      num_examples: 170
    - name: eval_fewshot
      num_bytes: 1636520
      num_examples: 188
  download_size: 44790710
  dataset_size: 183952610
configs:
  - config_name: default
    data_files:
      - split: train
        path: data/train-*
      - split: eval
        path: data/eval-*
      - split: eval_zeroshot
        path: data/eval_zeroshot-*
      - split: eval_fewshot
        path: data/eval_fewshot-*

2DNMRGym

This dataset contains more than 22,000 2D HSQC spectrum for atom-level graph learning tasks.

To use this data, please cite: [https://arxiv.org/abs/2505.18181]

Dataset Details

Dataset Description

HSQC is one important type of 2D NMR experiments, which is crucial in molecular discrimination and structure elucidation tasks. In 2DNMRGym, the train split is annotated by an established algorithm, which provides silver-standard labels for surrogated training. The evluation split is annotated by human experts with more than 10 years of training in organic chemistry, and provids high-quality gold-standard labels for model testing.

Dataset Sources [optional]

The raw data is sourced from HMDB and CH-NMR-NP.

Dataset Structure

Graph: dictionary presentation of pyg graph data. This is the molecular graph for each spectrum, containing node features and 3D coordinants.

C-peaks: the carbon chemical shift of the cross peaks in each HSQC spectrum, annotated to match the carbon indices in the molecular graph.

H-peaks: the proton chemical shifts of the cross peaks in each HSQC spectrum, annotated using the corresponding carbon indicies.

Who are the annotators?

Dr. Hao Xu - Harvard Medical School.

Dr. Wang Duosheng - Boston College.

Dr. Kumar Ambrish - University of Georgia.