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Mood Sensitive Stocks and Sustainable Cross-Sectional Returns During the COVID-19 Pandemic: An Analysis of Day of the Week Effect in the Chinese A-Share Market
This study examines two stock market anomalies and provides strong evidence of the day-of-the-week effect in the Chinese A-share market during the COVID-19 pandemic. Specifically, we examined the Quality minus Junk (QMJ) strategy return on Monday and FridayQuality stocks mean portfolio deciles that earn higher excess r...
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Effective management of patients with diabetes foot ulcers: outcomes of an Interprofessional Diabetes Foot Ulcer Team.
A longitudinal observational study on a convenience sample was conducted between 4 January and 31 December of 2010 to evaluate clinical outcomes that occur when a new Interprofessional Diabetes Foot Ulcer Team (IPDFUT) helps in the management of diabetes-related foot ulcers (DFUs) in patients living in a small urban co...
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Teachers’ Perspectives on Cyberbullying: A Cross-Cultural Study
The aim of this work is to analyze the perceptions of Colombian, Spanish, and Ecuadorian teachers regarding cyberbullying from a cross-cultural perspective. A descriptive and analytical method was used with a quantitative approach and 240 teachers answered an ad hoc questionnaire. Most teachers in the three countries s...
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WHOOP, Inc.: Digital Entrepreneurship During the Covid-19 Pandemic
This case is about WHOOP, Inc , a digital startup in the fitness technology space, how it responded to the Covid-19 pandemic, and its evolving business model and opportunities in the competitive wearables industry WHOOP launched as a wearable device company Its business model evolved from selling a device to providing ...
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Primary sigmoidectomy and appendicostomy for chronic idiopathic constipation.
PURPOSE To present our experience in patients with chronic idiopathic constipation complicated by megarectosigmoid and fecal incontinence who underwent a primary sigmoidectomy and appendicostomy. METHODS We reviewed eight patients referred to the Colorectal Center from 2014 to 2016 with chronic idiopathic constipation ...
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Changes In Mental Health, Social Engagement, and Physical Activities During the COVID-19 Pandemic
The current COVID-19 pandemic has profoundly changed our behaviors and health, especially vulnerable community-dwelling older adults. This symposium includes three presentations that evaluated the pandemic’s impacts on mental health, social engagement and physical activity in healthy community-living older adults and t...
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Lipid-lowering therapy in high cardiovascular risk patients during COVID-19 pandemic: keep focused on the target.
To the Editor COVID-19 (COrona VIrus Disease) patients with cardiovascular (CV) disease, multiple CV risk factors or comorbidities (i.e., arterial hypertension and diabetes) were shown to be more prone to a worse prognosis. SARS-CoV-2 is a still unknown enemy and the role of concomitant cardiovascular therapies has bee...
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Evaluation of a new simultaneous anti-SARS-CoV-2 IgA, IgM and IgG screening automated assay based on native inactivated virus
In addition to molecular testing, there is evolving interest for anti-SARS-CoV-2 antibodies serologic assays. Majority of them focus on IgM/IgG despite IgA important role in mucosal immunity. A simultaneous anti-SARS-CoV-2 IgA/IgG/IgM immunoassay, performed on an automated instrument by ELISA kit coated with native ina...
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Surveillance of COVID-19 Pandemic using Hidden Markov Model
COVID-19 pandemic has brought the whole world to a stand-still over the last few months. In particular the pace at which pandemic has spread has taken everybody off-guard. The Governments across the world have responded by imposing lock-downs, stopping/restricting travel and mandating social distancing. On the positive...
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When a nightmare comes true: Change in obsessive-compulsive disorder over the first months of the COVID-19 pandemic
The outbreak of the COVID-19 pandemic has particularly affected people with obsessive-compulsive disorder (OCD). Exacerbation of obsessive-compulsive symptoms (OCS) has been suspected for those with contamination-related OCD (C-OCD). However, the course of OCS over the ongoing pandemic remains unclear. We assessed 268 ...
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Americans’ Perspectives on Online Media Warning Labels
Americans are pervasively exposed to social media, news, and online content. Some of this content is designed to be deliberately deceptive and manipulative. However, it is interspersed amongst other content from friends and family, advertising, and legitimate news. Filtering content violates key societal values of free...
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Racial and Ethnic Disparities in the Prevalence of Stress and Worry, Mental Health Conditions, and Increased Substance Use Among Adults During the COVID-19 Pandemic — United States, April and May 2020
In 2019, approximately 51 million U.S. adults aged ≥18 years reported any mental illness,* and 7.7% reported a past-year substance use disorder† (1). Although reported prevalence estimates of certain mental disorders, substance use, or substance use disorders are not generally higher among racial and ethnic minority gr...
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Clinically oriented Alzheimer's biosensors: expanding the horizons towards point-of-care diagnostics and beyond
The development of minimally invasive and easy-to-use sensor devices is of current interest for ultrasensitive detection and signal recognition of Alzheimer's disease (AD) biomarkers. Over the years, tremendous effort has been made on diagnostic platforms specifically targeting neurological markers for AD in order to r...
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Perceived Effectiveness, Restrictiveness, and Compliance with Containment Measures against the Covid-19 Pandemic: An International Comparative Study in 11 Countries
National governments took action to delay the transmission of the coronavirus (SARS-CoV-2) by implementing different containment measures. We developed an online survey that included 44 different containment measures. We aimed to assess how effective citizens perceive these measures, which measures are perceived as vio...
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Vertical integration of primary care practices with acute hospitals in England and Wales: why, how and so what? Findings from a qualitative, rapid evaluation
OBJECTIVES: To understand the rationale, implementation and early impact of vertical integration between primary care medical practices and the organisations running acute hospitals in the National Health Service in England and Wales. DESIGN AND SETTING: A qualitative, cross-comparative case study evaluation at two sit...
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Challenges for the Future and the Role of Industrial Policy
The chapter summarizes the key ideas and issues described in previous chapters. The chapter offers a description of the kind of future we can envisage in the world healthcare industry, based on China’s growing role. Challenges and issues to be solved by China are considered. Key aspects discussed include: accessibility...
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Treatment Outcomes of IL-17 Inhibitors in Hidradenitis Suppurativa: A Systematic Review.
The IL-17 pathway is a potential therapeutic target shown to be implicated in hidradenitis suppurativa (HS), however, it remains unclear whether evidence from mechanistic studies may translate into clinical practice. This systematic review summarizes available treatment outcomes of IL-17 inhibitors in patients with HS....
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Robotically-assisted laparoscopic biliopancreatic diversion with duodenal switch: the utility of the robotic system in bariatric surgery.
Biliopancreatic diversion with duodenal switch (BPD/DS) is considered the most effective surgical option for morbidly obese patients. Several techniques have been described: open, laparoscopic, and the combination of open and laparoscopic. Only a few centers in the world perform robotically-assisted laparoscopic BPD/DS...
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Reposition of Montelukast either alone or in combination with Levocetirizine against SARS-CoV-2
It has been hypothesised that antiallergic medications (AAMs) like montelukast and levocetirizine both the two bitter chloro compounds could be repurposed either alone or combinedly as an antiviral against SARS-CoV-2, like chloroquine/hydroxychloroquine (CQ/HCQ), anorher two bitter chloro compounds. Both AAMs and CQ/HC...
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Assessment of Somatosensory Function and Self-harm in Adolescents
IMPORTANCE: Self-harm is a risk factor for suicide in adolescents, with the prevalence highest in young people in group and residential care programs. Although no established risk factors for self-harm exist, adolescents who self-harm may have decreased pain sensitivity, but this has not been systematically investigate...
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Emergently planned exclusive hub-and-spoke system in the epicenter of the first wave of COVID-19 pandemic in Italy: the experience of the largest COVID-19-free ICU hub for time-dependent diseases
BACKGROUND: Lombardy was the epicenter in Italy of the first wave of COVID-19 pandemic. To face the contagion growth, from March 8 to May 8 2020, a regional law re-designed the hub-and-spoke system for time-dependent diseases to better allocate resources for COVID-19 patients. METHODS: We report the reorganization of t...
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The geographic spread of infectious diseases Lisa Sattenspiel
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A systematic review and meta-analysis of the safety and efficacy of remifentanil and dexmedetomidine for awake fiberoptic endoscope intubation
BACKGROUND: Awake fiberoptic endoscope intubation (AFOI) is the primary strategy for managing anticipated difficult airways. Adequate sedation, most commonly being achieved with remifentanil and dexmedetomidine, is integral to this procedure. This meta-analysis aimed to compare the safety and efficacy of these 2 sedati...
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Communicable disease outbreaks: What is a case?
This second article in a series on communicable disease outbreaks focuses on case definitions, testing and early phases of a public health response.
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Association of In-Ear Device Use With Communication Quality Among Individuals Wearing Personal Protective Equipment in a Simulated Operating Room
Importance: The COVID-19 pandemic has brought forth new challenges for health care workers, such as the daily use of personal protective equipment, including reusable facial respirators. Poor communication while wearing respirators may have fatal complications for patients, and no solution has been proposed to date. Ob...
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Coevolution spreading in complex networks
Abstract The propagations of diseases, behaviors and information in real systems are rarely independent of each other, but they are coevolving with strong interactions. To uncover the dynamical mechanisms, the evolving spatiotemporal patterns and critical phenomena of networked coevolution spreading are extremely impor...
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Immunosuppression practices during the COVID-19 pandemic: A multinational survey study of transplant programs
During the COVID-19 pandemic, there has been wide heterogeneity in the medical management of transplant recipients. We aimed to pragmatically capture immunosuppression practices globally following the early months of the pandemic. From June to September 2020, we surveyed 1267 physicians; 40.5% from 71 countries partici...
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Kinetics of single and dual simultaneous infection of pigs with swine influenza A virus and porcine reproductive and respiratory syndrome virus
BACKGROUND: Simultaneous viral infections exhibit the phenomenon of viral interference, but understanding of the effect of one virus on another is limited. OBJECTIVE: Evaluate and compare clinical characteristics, immune and acute phase response, viral shedding and viral load in pigs singly and doubly inoculated with s...
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Comparative performance of fully-automated and semi-automated artificial intelligence methods for the detection of clinically significant prostate cancer on MRI: a systematic review
OBJECTIVES: We systematically reviewed the current literature evaluating the ability of fully-automated deep learning (DL) and semi-automated traditional machine learning (TML) MRI-based artificial intelligence (AI) methods to differentiate clinically significant prostate cancer (csPCa) from indolent PCa (iPCa) and ben...
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Low risk of COVID-19 infection in an ambulatory gastrointestinal endoscopy center in Argentina
Background and Objectives. Since the onset of the COVID-19 pandemic, concerns have been raised regarding the risk of infection to both healthcare staff and patients during gastrointestinal endoscopy procedures. Given the im-portance of performing routine endoscopic procedures to an individual’s future health, we sought...
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An Intelligent Multicriteria Model for Diagnosing Dementia in People Infected with Human Immunodeficiency Virus
Hybrid models to detect dementia based on Machine Learning can provide accurate diagnoses in individuals with neurological disorders and cognitive complications caused by Human Immunodeficiency Virus (HIV) infection. This study proposes a hybrid approach, using Machine Learning algorithms associated with the multicrite...
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Impact of the first COVID-19 shutdown on patient volumes and surgical procedures of a Level I trauma center
PURPOSE: In Dec 2019, COVID-19 was first recognized and led to a worldwide pandemic. The German government implemented a shutdown in Mar 2020, affecting outpatient and hospital care. The aim of the present article was to evaluate the impact of the COVID-19 shutdown on patient volumes and surgical procedures of a Level ...
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Inferring the true number of SARS-CoV-2 infections in Japan
IntroductionIn Japan, as of December 31, 2021, more than 1.73 million laboratory-confirmed cases have been reported. However, the actual number of infections is likely to be under-ascertained due to the epidemiological characteristics such as mild and subclinical infections and limited testing availability in the early...
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The impact of lower strength alcohol products on alcohol purchases: ARIMA analyses based on 4 million purchases by 69 803 households, 2015-2019.
BACKGROUND Lowering the strength of alcohol products could lead to less alcohol being bought and drunk. In its prevention White Paper, the UK Government aims to promote a significant increase in the availability of alcohol-free and low-alcohol products by 2025. METHODS Through descriptive analysis and ARIMA modelling o...
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The effect of increasing operator experience on procedure-related characteristics in patients undergoing carotid artery stenting.
Objectives To evaluate the efficacy and safety of carotid artery stenting for the treatment of severe carotid artery disease in our department and to investigate the effect of increasing operator experience on perioperative and procedure-related characteristics. Methods From January 2007 to February 2015 200 patients u...
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Narrowband-Internet of Things Device-to-Device Simulation: An Open-Sourced Framework
Narrowband-Internet of Things (NB-IoT) displays high-quality connectivity underpinned by fifth-generation (5G) networks to cover a wide array of IoT applications. The devices’ development and integration into different smart systems require permanent control, supervision, and the study of power consumption models to de...
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Reducing contacts to stop SARS-CoV-2 transmission during the second pandemic wave in Brussels, Belgium, August to November 2020
To evaluate the effect of physical distancing and school reopening in Brussels between August and November 2020, we monitored changes in the number of reported contacts per SARS-CoV-2 case and associated SARS-CoV-2 transmission. The second COVID-19 pandemic wave in Brussels was the result of increased social contact ac...
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How do community pharmacies in Ontario manage drug shortage problems? Results of an exploratory qualitative study.
Background Pharmacists report spending a considerable amount of time dealing with drug shortages. There is no research in Canada identifying and describing the strategies and resources that pharmacists use to minimize disruption and continuity of care for patients. Methods An exploratory qualitative methodology was use...
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The impact of COVID-19 on the operations and management of NGOs: resilience and recommendations
Purpose The COVID-19 pandemic has made humanity contend with the negative footprint of its activities in which social justice, ecological integrity and economic stability are compromised. This study aims to investigate the impact of COVID-19 on the operation and management of non-governmental organisations (NGOs) in Ni...
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Forty years with coronaviruses
I have been researching coronaviruses for more than forty years. This viewpoint summarizes some of the major findings in coronavirus research made before the SARS epidemic and how they inform current research on the newly emerged SARS-CoV-2.
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Application of Deep Learning for Fast Detection of COVID-19 in X-Rays using nCOVnet
Presently, COVID-19 has posed a serious threat to researchers, scientists, health professionals, and administrations around the globe from its detection to its treatment. The whole world is witnessing a lockdown like situation because of COVID-19 pandemic. Persistent efforts are being made by the researchers to obtain ...
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Photocatalytic Degradation of Plastic Waste: A Mini Review
Plastic waste becomes an immediate threat to our society with ever-increasing negative impacts on our environment and health by entering our food chain. Sunlight is known to be the natural energy source that degrades plastic waste at a very slow rate. Mimicking the role of sunlight, the photocatalytic degradation proce...
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Cervical Cancer Screening with HPV Testing: Updates on the Recommendation.
The present update is a reassessment of the 2018 'Guidelines for HPV-DNA Testing for Cervical Cancer Screening in Brazil' (Zeferino et al.)9, according to the changes observed in new international guidelines and knowledge updates. The most relevant and recent guidelines were assessed. Questions regarding the clinical p...
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Hydroxychloroquine and chloroquine in COVID-19: should they be used as standard therapy?
The pandemic of the new coronavirus, known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has urged the nations to an unprecedented world-wide reaction, including an accelerated exploration of therapeutic options. In the absence of a vaccine and specifically designed antivirals, the medical community ...
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Symptomatic Carotid Artery Thrombosis in a Patient Recently Recovered From a COVID-19 Infection
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), was initially discovered in December 2019 in China and rapidly spread all over the world to become a pandemic. The most common symptoms of a disease are fever, cough, generalized body ache, weakness, dyspnoea, n...
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Is Gut Involvement a Cause or Effect of COVID-19?
Digestive disorder symptoms in COVID-19 may be similar in form to post-infectious functional gastrointestinal disorder (PI-FGID). To cause clinical effects, SARS-CoV-2 must reach the bowels and gastric hypochlorhydria may facilitate such transit. Asian elderly are predisposed to greater infection rate and severity of C...
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NCI Workshop on Artificial Intelligence in Radiation Oncology: Training the Next Generation
Abstract Artificial intelligence (AI) is about to touch every aspect of radiotherapy from consultation, treatment planning, quality assurance, therapy delivery, to outcomes modeling. There is an urgent need to train radiation oncologists and medical physicists in data science to help shepherd AI solutions into clinical...
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ProReal®: The ‘good enough’ online alternative to face-to-face Dramatherapy
The Covid-19 restrictions have limited the access of face-to face therapies for many people and continues to effect how Dramatherapists operate. The following article offers reflections around adapting to an on-line medium, focusing more specifically around the software of ProReal. Limitations and considerations are ac...
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Mitochondrial RNA, a new trigger of the innate immune system.
Mitochondria play a pivotal role in numerous cellular processes. One of them is regulation of the innate immune pathway. In this instance, mitochondria function in two different aspects of regulatory mechanisms. First, mitochondria are part of the antiviral signaling cascade that is triggered in the cytoplasm and trans...
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Screening for Dental Infections Achieves 6-Fold Reduction in Dental Emergencies During Induction Chemotherapy for Acute Myeloid Leukemia
PURPOSE: Patients with newly diagnosed acute myeloid leukemia (AML) are at risk of infection, including odontogenic infections, during induction chemotherapy. It is unknown whether clinical dental screening to diagnose and treat odontogenic disease in these patients can reduce the incidence of dental emergencies. METHO...
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SARS-CoV-2 RNA detection and persistence in wastewater samples: An experimental network for COVID-19 environmental surveillance in Padua, Veneto Region (NE Italy)
Background Clinical detection of SARS-CoV-2 RNA in stools supports the idea of wastewater-based epidemiology (WBE) as a precious tool for COVID-19 environmental surveillance. Successful detection of SARS-CoV-2 RNA in untreated wastewaters has been reported in several countries. This study investigated the presence and ...
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Healthcare-acquired clusters of COVID-19 across multiple wards in a Scottish health board
BACKGROUND: Healthcare-acquired COVID-19 has been an additional burden on hospitals managing increasing numbers of patients with SARS-CoV-2. One acute hospital (W) among three in a Scottish healthboard experienced an unexpected surge of COVID-19 clusters. AIM: To investigate possible causes of COVID-19 clusters at Hosp...
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Lung-resident memory B cells established after pulmonary influenza infection display distinct transcriptional and phenotypic profiles.
Recent studies have established that memory B cells, largely thought to be circulatory in the blood, can take up long-term residency in inflamed tissues, analogous to widely described tissue-resident T cells. The dynamics of recruitment and retention of memory B cells to tissues and their immunological purpose remains ...
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False sense of safety by daily QTc interval monitoring during methadone IVPCA titration in a patient with chronic pain.
It has been proposed that some deaths attributed to methadone are related to prolongation of the QTc interval; however, there are no clear recommendations on electrocardiogram (ECG) monitoring in patients undergoing intravenous methadone infusion. This is a report on a patient receiving methadone intravenous patient-co...
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View Point (Editorial)
Agile helps teams focus on developing team-oriented goals, reflecting on their work and making needed adaptations at regular intervals and using agile practices to have authentic group interactions which lead to improved team dynamics and fostering innovation (Smith and Sidky, 2009). According to a recent survey (Versi...
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Covid-19 telescreening in SUS users with risk conditions: case report
ABSTRACT This case report aims to describe the conception and preliminary data of the implementation of a telescreening and telemonitoring program of covid-19 for users of the Unified Health System with risk conditions A system of telerscreening was implemented through which undergraduate students in the health area co...
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Power Distance Belief and Workplace Communication: The Mediating Role of Fear of Authority
Power distance is the degree of acceptance of unequal distribution of power in societies. In a high power distance context, the acceptance of inequality conflicts with the operation of modern organizations, which causes obstacles to workplace communication or even triggers workplace accidents due to ineffective communi...
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Peptidyl Fluoromethyl Ketones and Their Applications in Medicinal Chemistry
Peptidyl fluoromethyl ketones occupy a pivotal role in the current scenario of synthetic chemistry, thanks to their numerous applications as inhibitors of hydrolytic enzymes. The insertion of one or more fluorine atoms adjacent to a C-terminal ketone moiety greatly modifies the physicochemical properties of the overall...
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An 11-Year-Old Saudi Arabian Girl Who Presented with Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with SARS-CoV-2 Infection with Coronary Artery Aneurysm and Cardiac Involvement: A Case Report
Patient: Female, 11-year-old Final Diagnosis: Pediatrics multisystem inflammatory syndrome Symptoms: Cough • fever • shortness of breath Medication: — Clinical Procedure: — Specialty: Infectious Diseases OBJECTIVE: Unusual clinical course BACKGROUND: Early in the COVID-19 pandemic, children who were infected with sever...
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Physical Activity and Depression in Adolescents: Evidence from China Family Panel Studies
Depression in adolescents is a major public health disorder. The relationship between physical activity and risk of depression in adolescents was examined using three waves of data from the China Family Panel Studies in 2020. The risk of depression was significantly higher among adolescents who reported lower frequency...
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The relation between knowledge and concern: A global study of children and COVID-19
COVID-19 messages vary around the world, and populations receive these messages in different ways. Children are a vulnerable audience, especially in terms of risk communication. As messages are being developed, communicated, and disseminated about this pandemic, it is important to know the relation between COVID-19 kno...
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COVID-19 and gynecological cancers: Asia and Oceania Federation of Obstetrics and Gynecology oncology committee opinion
Since the outbreak of COVID-19, there have already been over 26 million people being infected and it is expected that the pandemic will not end in near future. Not only the daily activities and lifestyles of individuals have been affected, the medical practice has also been modified to cope with this emergency catastro...
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Oral Health Conditions and COVID-19: A Systematic Review and Meta-analysis of the Current Evidence
BACKGROUND: : The coronavirus disease 2019 (COVID-19) pandemic has highlighted the importance of understanding the underlying conditions that lead to COVID-19. Oral health has systemic implications in the maintenance of a healthy state. This study aimed to summarize evidence on the prevalence of oral health conditions ...
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Evaluating the contribution of synthetic fungicides to cereal plant health and CO2 reduction targets against the backdrop of the increasingly complex regulatory environment in Europe
The global COVID pandemic has impacted the world in ways and at a scale that few could have predicted, with many industries severely disrupted. Despite this, crops were sown and harvested, food was produced and agriculture continued to function, albeit it with many logistical challenges. Plant health lies at the heart ...
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Who is watching? Refugee protection during a pandemic - responses from Uganda and South Africa
Both Uganda and South Africa were quick to respond to the global pandemic – Uganda for example imposing quarantine on foreign travellers after only a handful of cases before shutting off all international flights, and South Africa imposing one of the first lockdowns on the continent. Reflecting on the first 6 months of...
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Development of Learning Media for Android-Based during the COVID-19 Pandemic
Android-based learning media is expected to be the precise choice during the pandemic outbreak. Learning and teaching activity can still be conducted even if only through online learning. In accordance with the development of information technology which is growing rapidly around the world, especially among vocational ...
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Time of Bariatric Surgery and Hospitalization for SARS-CoV-2: a Nationwide Study
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Scientometrics analysis of recent trends in Global Corona virus Research
Background: The worldwide pandemic COVID-19 has produced a wealth of research more rapidly after the outbreak. In just a couple of months, there is a rise in several studies on Coronavirus, adding up to the scholarly literature. Method: The current study attempts to Scientometric analyze very recent literature on Coron...
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Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection
In this retrospective study, chest CTs of 121 symptomatic patients infected with coronavirus disease-19 (COVID-19) from four centers in China from January 18, 2020 to February 2, 2020 were reviewed for common CT findings in relationship to the time between symptom onset and the initial CT scan (i.e. early, 0-2 days (36...
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Insights into financial technology (FinTech): a bibliometric and visual study
This paper conducted a comprehensive analysis based on bibliometrics and science mapping analysis. First, 848 publications were obtained from Web of Science. Their fundamental characteristics were analyzed, including the types, annual publications, hot research directions, and foci (by theme analysis, co-occurrence ana...
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The impact of COVID-19 news, panic and media coverage on the oil and gold prices: An ARDL approach
This study investigates whether COVID-19 news, panic and media coverage affect oil and gold prices Using the ARDL approach over the period January 23, 2020 to June 23, 2020, we find that COVID-19 deaths and panic have negative effects on crude oil price However, the propaganda created by the media in the long term has ...
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[the Attitude of Young People to the New Coronavirus Infection: the Dynamics of Ideas and Practices of Health-saving Behavior]
The article examines the dynamics of the attitude of young people about the new coronavirus infection. The attitude of young people to the new coronavirus infection is formed in two types of reality: «online¼ and «offline¼. The views, assessments and knowledge of young people about the new coronavirus infection were si...
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Vaccination as a possible trigger for immune-mediated necrotising myopathy.
Immune-mediated necrotising myopathy is a rare autoimmune myopathy characterised by severe progressive muscle weakness, elevated levels of creatine kinase (CK), and necrosis with minimal inflammatory cell infiltration on muscle biopsy. We report a case of a previously healthy 42-year-old woman who presented with progre...
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A Veterinary Vaccine for SARS-CoV-2: The First COVID-19 Vaccine for Animals
As coronaviruses have a wide range of host species, many animals harbor these pathogens, however only a handful of them become severely infected [...].
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Effect of hepatitis C antiviral therapy on oral lichen planus and hyposalivation in inmates
BACKGROUND: Oral lichen planus (OLP) and hyposalivation have been reported as extrahepatic manifestations of hepatitis C virus (HCV) infection. Our study evaluated the effect of direct antiviral agents (DAAs) on OLP and hyposalivation in convicts with chronic hepatitis C, examining patients before, during and after the...
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Staffing and Capacity Planning for SARS-CoV-2 Monoclonal Antibody Infusion Facilities: A Performance Estimation Calculator Based on Discrete-Event Simulations
BACKGROUND: The COVID-19 pandemic has significantly stressed healthcare systems. The addition of monoclonal antibody (mAb) infusions, which prevent severe disease and reduce hospitalizations, to the repertoire of COVID-19 countermeasures offers the opportunity to reduce system stress but requires strategic planning and...
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The SARS-CoV-2 spike protein primes inflammasome-mediated interleukin-1- beta secretion in COVID-19 patient-derived macrophages
Innate immunity triggers responsible for viral control or hyperinflammation in COVID- 19 are largely unknown. Here we show that the SARS-CoV-2 spike protein primes inflammasome activation and interleukin 1-beta (IL-1β) secretion in macrophages derived from COVID-19 patients but not in macrophages from healthy SARS-CoV-...
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Temporal associations of B and T cell immunity with robust vaccine responsiveness in a 16-week interval BNT162b2 regimen
Spacing of the BNT162b2 mRNA doses beyond 3 weeks raised concerns about vaccine efficacy. We longitudinally analyzed B cell, T cell and humoral responses to two BNT162b2 mRNA doses administered 16 weeks apart in 53 SARS-CoV-2 naïve and previously-infected donors. This regimen elicited robust RBD-specific B cell respons...
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Variations In Spectrum Of Covid-19 Ct Findings And Its Severity Scoring In A Tertiary Care Hospital Of Bahawalpur, Southern Punjab Pakistan
BACKGROUND: Recently the Coronavirus pandemic presented with different manifestations in different parts of the world, both on clinical examinations and on imaging CT Scanning (CT Scan) chest is used for detailed evaluation of the different characteristic patterns determining the depth of disease The study is aimed to ...
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Predicting the Kidney Graft Survival Using Optimized African Buffalo-Based Artificial Neural Network
A variety of receptor and donor characteristics influence long-and short-term kidney graft survival. It is critical to predict the effectiveness of kidney transplantation to optimise organ allocation. This would allow patients to choose the best accessible kidney donor and the optimal immunosuppressive medication. Seve...
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Genetic Manipulation of Human Intestinal Enteroids Demonstrates the Necessity of a Functional Fucosyltransferase 2 Gene for Secretor-Dependent Human Norovirus Infection
Human noroviruses (HuNoVs) are the leading cause of nonbacterial gastroenteritis worldwide. Histo-blood group antigen (HBGA) expression is an important susceptibility factor for HuNoV infection based on controlled human infection models and epidemiologic studies that show an association of secretor status with infectio...
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Recommendations for head and neck surgical oncology practice in a setting of acute severe resource constraint during the COVID-19 pandemic: an international consensus
The speed and scale of the global COVID-19 pandemic has resulted in unprecedented pressures on health services worldwide, requiring new methods of service delivery during the health crisis. In the setting of severe resource constraint and high risk of infection to patients and clinicians, there is an urgent need to ide...
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COVID-19: Vaccine Delivery System, Drug Repurposing and Application of Molecular Modeling Approach
The acute respiratory syndrome coronavirus (SARS-CoV-2) has spread across the world, resulting in a pandemic COVID-19 which is a human zoonotic disease that is caused by a novel coronavirus (CoV) strain thought to have originated in wild or captive bats in the initial COVID outbreak region. The global COVID-19 outbreak...
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Emergent and urgent otologic surgeries during the SARS-CoV-2 pandemic: a protocol and review of literature
OBJECTIVE: To review guidelines for otologic procedures during the SARS-CoV-2 pandemic and to present a protocol for emergent or urgent mastoidectomy at our institution. DATA SOURCES: Guidelines regarding emergent and urgent otologic procedures from otolaryngologic societies are reviewed. We described a protocol for em...
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Recomendaciones sobre reanimación cardiopulmonar en pacientes con sospecha o infección confirmada por SARS-CoV-2 (COVID-19). Resumen ejecutivo
Resumen La pandemia por SARS-CoV-2 ha generado nuevos escenarios que requieren modificaciones de los protocolos habituales de reanimación cardiopulmonar. Las guías clínicas vigentes sobre el manejo de la parada cardiorrespiratoria no incluyen recomendaciones para situaciones aplicables a este contexto. Por ello, el Pla...
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Correction to: Inhaled nitric oxide in patients admitted to intensive care unit with COVID-19 pneumonia
An amendment to this paper has been published and can be accessed via the original article.
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Preoperative Noninvasive Mapping Allowed Targeted Concomitant Surgical Ablation and Revealed COVID-19 Infection
In March 2020, a 64-year-old female with mitral valve insufficiency and persistent atrial fibrillation underwent preoperative noninvasive mapping for developing an ablation strategy. In the computed tomography (CT) scan, typical signs of COVID-19 were described. Since the consecutive polymerase chain reaction (PCR) tes...
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An atypical case of COVID-19 and renal amyloidosis presenting with brash syndrome
INTRODUCTION: The syndrome of bradycardia, renal failure, atrioventricular nodal blockade (AVNB), shock and hyperkalemia (BRASH) represents a persistent cycle of pre-existing renal disease and hyperkalemia worsened by bradycardia, hypoperfusion and an AVNB agent We report a continuous cycle of BRASH triggered by COVID-...
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COVID-19 response in South-East Asia: promoting healthcare quality through political engagement
Coronavirus disease-2019 (COVID-19), a disease caused by coronavirus severe acute respiratory syndrome coronavirus 2, led to a pandemic that affected every region of the world. The World Health Organization South-East Asia Region (SEARO) is composed of 11 countries: Bangladesh, Bhutan, Democratic People’s Republic of K...
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Etanercept Ameliorates Cardiac Fibrosis in Rats with Diet-Induced Obesity
Diet-induced obesity (DIO) is considered the main risk factor for cardiovascular diseases. Increases in the plasma levels of tumor necrosis factor alpha (TNF-α) is associated with DIO. Etanercept, a TNF-α inhibitor, has been shown to alleviate cardiac hypertrophy. To investigate the effect of etanercept on cardiac fibr...
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Covid-19 virus diffusion in Italy: Data quality and methodological challenges
In early 2020, it emerged in Italy a large outbreak of Covid-19, the infectious disease caused by severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). In this context, producing as accurate as possible forecasting models was crucial both for the containment of the epidemic and for the planning of effective pol...
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Crisis as a chance. A digital training of social competencies with simulated persons at the Medical Faculty of RWTH Aachen, due to the lack of attendance teaching in the SARS-Cov-2 pandemic
Objective: The AIXTRA Competence Center for Training and Patient Safety at RWTH Aachen University has developed a concept to enable learning of communication skills with simulated persons (SP) digitally. Methodology: Existing SP cases in curricular teaching were checked for digital applicability and modified. Digital s...
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Association between vitamin D level and prognostic factors among patients infected with SARS-CoV-2.
OBJECTIVES The present study aimed to evaluate the presence of any relationship between vitamin D and prognostic factors among patients infected with SARS-CoV-2. METHODS This retrospective cross-sectional study was conducted among patients admitted from March to August 2020 in a referral hospital, Tehran, Iran. All pat...
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Polymeric surfaces with biocidal action: challenges imposed by the SARS-CoV-2, technologies employed, and future perspectives
The COVID-19 pandemic has demonstrated that hygiene habits reduce the spread of the SARS-CoV-2 virus on contaminated surfaces In this context, compounds with biocidal properties can act as surface coatings, especially in hospital environments, a source of pathogenic microorganisms Therefore, the purpose of this review ...
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Review the safety of Covid-19 mRNA vaccines: a review
The novel coronavirus disease 2019 (COVID-19) has infected more than 100 million people globally within the first year of the pandemic. With a death toll surpassing 500,000 in the United States alone, containing the pandemic is predicated on achieving herd immunity on a global scale. This implies that at least 70-80 % ...
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Interest in dentistry in early months of the COVID‐19 global pandemic: A Google Trends approach
BACKGROUND: In early the COVID‐19 pandemic, routine dental treatments have been delayed due to the risk of disease transmission. This delay may lead public to search for information on the Internet for a solution. OBJECTIVES: This study aims to evaluate the public interest in dentistry in the early months of the COVID‐...
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Willingness to Vaccinate Children against Influenza after the Coronavirus Disease 2019 Pandemic
OBJECTIVES: To determine factors associated with parents who plan to vaccinate their children against influenza next year, especially those who did not vaccinate against influenza last year using a global survey. STUDY DESIGN: A survey of caregivers accompanying their children aged 1-19 years old in 17 pediatric emerge...
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COVID-19 and liver transplantation
The effect of coronavirus disease 2019 (COVID-19) on liver transplantation programmes and recipients is still not completely understood but overall involves the risk of donor-derived transmission, the reliability of diagnostic tests, health-care resource utilization and the effect of immunosuppression. This Comment rev...
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Effectiveness and satisfaction of technology‐mediated learning during global crisis: understanding the role of pre-developed videos
Purpose: In today’s dynamic situation, innumerable challenges are posited in the education sector because of the COVID-19 pandemic. Higher educational institutes (HEIs) are compelled to adopt digital technologies and technology-mediated learning in the teaching-learning processes. The purpose of this paper is to unders...
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Retinal microvascular signs in COVID-19
BACKGROUND/AIMS: To explore if retinal findings are associated with COVID-19 infection. METHODS: In this prospective cross-sectional study, we recruited participants positive for COVID-19 by nasopharyngeal swab, with no medical history. Subjects underwent retinal imaging with an automated imaging device (3D OCT-1 Maest...
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