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Why Blood Group A Individuals Are at Risk Whereas Blood Group O Individuals Might Be Protected from SARS-CoV-2 (COVID-19) Infection: A Hypothesis Regarding How the Virus Invades the Human Body via Abo(H) Blood Group-Determining Carbohydrates
While the angiotensin converting enzyme 2 (ACE2) protein is defined as the primary severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor, the viral serine molecule might be mobilized by the host's transmembrane protease serine subtype 2 (TMPRSS2) enzyme from the viral spike (S) protein and hijack the ho...
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Point-of-care tests for influenza A and B viruses and RSV in emergency departments – indications, impact on patient management and possible gains by syndromic respiratory testing, Capital Region, Denmark, 2018
BACKGROUND: Point-of-care tests (POCT) for influenza A and B viruses and respiratory syncytial virus (RSV) were implemented in emergency departments of all hospitals in the Capital Region of Denmark in 2018. AIM: To establish whether POC testing for influenza viruses or RSV is based on a valid respiratory symptom indic...
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Implementation of Brain Breaks(®) in the Classroom and Its Effects on Attitudes towards Physical Activity in a Chinese School Setting
This study aimed to examine the effects of three-months of classroom-based Brain Breaks Physical Activity Solution (Brain Breaks(®)) on attitudes toward physical activity levels of primary school children in Henan Province, China. The participants were 704 children enrolled in grades 3–5 who were randomly assigned to e...
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Seroprevalence of hospital staff in a province with zero COVID-19 cases
BACKGROUND: COVID-19 seroprevalence data, particularly in less developed countries with a relatively low incidence, has been scant. We aimed to explore the seroprevalence of hospital staff in the area with zero confirmed COVID-19 case to shed light on the situation of COVID-19 infection in zero or low infection rate co...
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Bioactive compounds from marine resources against novel corona virus (2019-nCoV): in silico study for corona viral drug.
Present research reports the molecular docking analysis of 2019-nCoV inhibition by antiviral compounds from marine natural resources. For this study, the structure of ligand (antiviral compound) and 2019-nCoV main protease (Mpro) was received from the databases of PubChem and Protein Data Bank (PDB), respectively. Mole...
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Implementation of the cobas Liat influenza point-of-care test into an emergency department during a high-incidence season: a retrospective evaluation following real-world implementation
The cobas Liat influenza A/B and respiratory syncytial virus (RSV) assay (Liat) was used in the adult emergency department of a large London hospital from 21(st) January 2018 to 14(th) April 2018. Influenza was detected in 308 of 1027 (30%) samples tested; influenza A in 157 (15.3%), influenza B in 149 (14.5%) and RSV ...
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Wie ernähre ich mich am besten in Zeiten der Corona-Pandemie?: COVID-19 und Ernährungsmedizin
Die aktuelle Corona-Pandemie betrifft nahezu alle Bereiche der Medizin und des täglichen Lebens. Dementsprechend häufig tauchen Fragen zum Stellenwert der Ernährung auf, z. B. welche Ernährung einen Schutz vor der Corona-Infektion bieten kann und welche Bedeutung die Ernährung im Krankheitsverlauf hat.
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Psychological impact of COVID-19 lockdown in children and adolescents from San Carlos de Bariloche, Argentina: Parents' perspective./ Impacto psicológico del aislamiento por COVID-19 en jóvenes de San Carlos de Bariloche, Argentina: la mirada de los padres
INTRODUCTION: From an infectious perspective, children and adolescents were not highly affected by the COVID-19 pandemic. However, social isolation measures have deeply changed their lifestyle, which is believed to have a psychological impact on them. The objective was to assess the impact of COVID-19 lockdown on the e...
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Efficacy and safety of hydroxychloroquine as add-on therapy in uncontrolled type 2 diabetes patients who were using two oral antidiabetic drugs
OBJECTIVE: To evaluate the Safety and Efficacy of Hydroxychloroquine as add-on therapy in uncontrolled type 2 diabetes patients who were using two oral antidiabetic drugs. MATERIALS AND METHODS: This was a double blind, placebo controlled, parallel group study in 304 inadequately controlled type 2 diabetes (T2DM) subje...
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Qualitative study on the shifting sociocultural meanings of the facemask in Hong Kong since the severe acute respiratory syndrome (SARS) outbreak: implications for infection control in the post-SARS era
BACKGROUND: The clinical importance and efficacy of facemasks in infection prevention have been documented in the international literature. Past studies have shown that the perceived susceptibility, the perceived severity of being afflicted with life-threatening diseases, and the perceived benefits of using a facemask ...
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Confronting medication scarcity in the era of COVID-19
Over the past decade, US patients and clinicians have endured medication shortages of nearly every class, including many lifesaving medications These shortages have persisted despite determined efforts by federal, academic, and professional organizations Medication shortages have resulted in lost lives, medication erro...
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Modeling Shock Propagation on Supply Chain Networks: A Stochastic Logistic-Type Approach
Supply Chains have been more and more suffering from unexpected industrial, natural events, or epidemics that might disrupt the normal flow of materials, information, and money. The recent pandemic triggered by the outbreak of the new COVID-19 has pointed out the increasing vulnerability of supply chain networks, promp...
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Computational insight of dexamethasone against potential targets of SARS-CoV-2
The health sector has been on the race to find a potent therapy for coronavirus disease (COVID)-19, a diseases caused by severe acute respiratory syndrome coronavirus (SARS-CoV)-2. Repurposed anti-viral drugs have played a huge role in combating the virus, and most recently, dexamethasone (Dex) have shown its therapeut...
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COVID-19, recovery policies and the resilience of EU ETS
COVID-19 pandemic and its recovery bring opportunities and threats for global climate governance and further challenge climate related assets. In this study, we analyze the efficiency of government response policies and fiscal policies on green recovery by observing the variation characteristics of carbon allowance pri...
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Measles transmission during a large outbreak in California
A large measles outbreak in 2014–2015, linked to Disneyland theme parks, attracted international attention, and led to changes in California vaccine policy. We use dates of symptom onset and known epidemic links for California cases in this outbreak to estimate time-varying transmission in the outbreak, and to estimate...
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Tourism recovery strategy against COVID-19 pandemic
Travel is requisite for tourism activity, therefore, any factor that hinders traveling may have a profound impact on the tourism industry. This includes pandemics such as COVID-19. Therefore, it is important to have well thought out tourism crisis and disaster management (TCDM) to mitigate the impact and help with post...
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Implementation of a fracture liaison service for patients with hip fracture cared for on a hospital medicine service.
OBJECTIVE Hip fracture is a common and morbid condition. Prior studies have shown that the majority of patients with fragility fracture are not treated for underlying osteoporosis. Our hospitalist-led co-management service for patients with acute hip fracture had no system for evaluating and treating osteoporosis in th...
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Burnout among Portuguese radiographers during the COVID-19 pandemic
INTRODUCTION: The COVID-19 pandemic has had a global impact, including in health services, placing health professionals under enormous tension, pressure, and stress. Professionals involved in the care, diagnosis, and treatment of COVID-19-infected patients have been subject to emotional and physical distress that can p...
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From Zero to a National Data Set in 2 Weeks: Reflections on a COVID-19 Collaborative Survey Project
In March 2020, like much of the rest of the world, we went into lockdown A week into our new reality, we decided to do a survey study about how people were experiencing the COVID-19 pandemic In this piece, we describe what motivated us to do the study, how we went about it, and what others can learn from our experience...
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Prediction Models for the Clinical Severity of Patients With COVID-19 in Korea: Retrospective Multicenter Cohort Study
BACKGROUND: Limited information is available about the present characteristics and dynamic clinical changes that occur in patients with COVID-19 during the early phase of the illness. OBJECTIVE: This study aimed to develop and validate machine learning models based on clinical features to assess the risk of severe dise...
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Novel COVID-19 Screening Using Cough Recordings of A Mobile Patient Monitoring System
Since the COVID-19 pandemic began, research has shown promises in building COVID-19 screening tools using cough recordings as a convenient and inexpensive alternative to current testing techniques. In this paper, we present a novel and fully automated algorithm framework for cough extraction and COVID-19 detection usin...
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The relationship between new PCR positive cases and going out in public during the COVID-19 epidemic in Japan
The suppression of the first wave of COVID-19 in Japan is assumedly attributed to people’s increased risk perception after acquiring information from the government and media reports. In this study, going out in public amidst the spread of COVID-19 infections was investigated by examining new polymerase chain reaction ...
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Polio Virotherapy of Malignant Glioma Engages the Tumor Myeloid Infiltrate and Induces Diffuse Microglia Activation
Malignant gliomas commandeer abundant inflammatory infiltrates with glioma-associated macrophages and microglia (GAMM) actively promoting tumor progression. Like all cells in the mononuclear phagocytic system, macrophages and microglia constitutively express the poliovirus receptor, CD155. Besides myeloid cells, CD155 ...
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The road to a human-centred digital society: opportunities, challenges and responsibilities for humans in the age of machines
The growing adoption of intelligent technologies has brought us to a crossroad. The creators of intelligent technologies are acquiring the power to influence a wide variety of outcomes that are important to human end-users. In doing so, those same intelligent technologies are being used to undermine and even actively h...
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Using Student Insights for Ideas on Video Creation for Chemistry Classes
Creation of videos is one of the many ways faculty and teachers have had to cope with the limitations of teaching chemistry laboratory at this time of COVID-19 restrictions In this communication, I describe ideas for videos generated by students in a class I taught entitled Teaching of Biology The students were require...
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Using a genetic algorithm to fit parameters of a COVID-19 SEIR model for US states
Background: A Susceptible-Exposed-Infected-Removed (SEIR) model was developed to forecast the spread of the novel coronavirus (SARS-CoV-2) in the United States and the implications of re-opening and hospital resource utilization The model relies on the specification of various parameters that characterize the virus and...
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Understanding national trends in COVID-19 vaccine hesitancy in Canada: results from five sequential cross-sectional representative surveys spanning April 2020–March 2021
OBJECTIVE: To examine rates of vaccine hesitancy and their correlates among Canadian adults between April 2020 and March 2021. DESIGN: Five sequential cross-sectional age, sex and province-weighted population-based samples who completed online surveys. SETTING: Canada. PARTICIPANTS: A total of 15 019 Canadians aged 18 ...
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The folate antagonist methotrexate diminishes replication of the coronavirus SARS-CoV-2 and enhances the antiviral efficacy of remdesivir in cell culture models
The search for successful therapies of infections with the coronavirus SARS-CoV-2 is ongoing. We tested inhibition of host cell nucleotide synthesis as a promising strategy to decrease the replication of SARS-CoV-2-RNA, thus diminishing the formation of virus progeny. Methotrexate (MTX) is an established drug for cance...
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Natural Substances in the Fight of SARS-CoV-2: A Critical Evaluation Resulting from the Cross-Fertilization of Molecular Modeling Data with the Pharmacological Aspects
The recent pandemic due to SARS-CoV-2, the last isolated human beta-coronavirus, has revolutionized modern knowledge of the pathogenesis of viral pneumonia. The lack of specific antiviral drugs and the need to develop adequate research for new antiviral drugs capable of treating this new form of the disease undertook t...
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More eyes on COVID-19: Perspectives from Ethics The most powerful health-promoting forces in COVID-19 are social
As the COVID-19 pandemic rages through the world, all aspects of life globally are being disrupted by mounting death rates and governments' responses The first ethical lesson has been the realization that the increasing instability of the world, characterized by diverging trajectories of health and well-being, with a m...
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The decrease of CD4 T cell is associated with mortality in critical inpatients with COVID-19
Background: The 2019 novel coronavirus (SARS-CoV-2) has caused an outbreak in the world. The critically ill patients had a high mortality. However, the possible risk factors of critical patients with coronavirus disease 2019 (COVID-19) are not fully known. We aim to investigate the risk factors in critical patients wit...
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Modeling COVID-19 Dynamics in Illinois under Nonpharmaceutical Interventions
We present modeling of the COVID-19 epidemic in Illinois, USA, capturing the implementation of a stay-at-home order and scenarios for its eventual release We use a non-Markovian age-of-infection model that is capable of handling long and variable time delays without changing its model topology Bayesian estimation of mo...
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An Open-Source Modular Framework for Automated Pipetting and Imaging Applications
The number of samples in biological experiments are continuously increasing, but complex protocols and human experimentation in many cases lead to suboptimal data quality and hence difficulties in reproducing scientific findings. Laboratory automation can alleviate many of these problems by precisely reproducing machin...
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“‘Ninja’ levels of focus”: Therapeutic holding environments and the affective atmospheres of telepsychology during the COVID-19 pandemic
The COVID-19 crisis in Australia led to a rapid increase in the use of telehealth services to offer psychological therapy (often referred to as ‘telepsychology’). In this article, we discuss the intersection of the social psychology concepts of therapeutic holding spaces and containment with more-than-human theory as i...
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Shedding a new light on Huntington's disease: how blood can both propagate and ameliorate disease pathology.
Huntington's disease (HD) is a monogenic neurodegenerative disorder resulting from a mutation in the huntingtin gene. This leads to the expression of the mutant huntingtin protein (mHTT) which provokes pathological changes in both the central nervous system (CNS) and periphery. Accumulating evidence suggests that mHTT ...
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A Prediction Model for High Risk of Positive RT-PCR Tests in Discharged Patients with COVID-19 Based on Random Forest Model
Several recent studies have reported that a few patients had positive SARS-CoV-2 RNA tests after hospital discharge. The high-risk factors associated with these patients remain to be identified. A total of 463 patients with COVID-19 discharged from Leishenshan Hospital in Wuhan, China, between February 8 and March 8, 2...
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Acute abdominal pain due to internal herniation of the sigmoid colon, fallopian tube and left ovary, a rare presentation of Allen Masters syndrome.
In 1955, Allen and Masters describe a painful syndrome which associates traumatic delivery to laceration found on the posterior leaf of the broad ligament. Herniation through this defect is a rare entity, accounted for about 4-7% of all internal hernias. Normally, it involves the small bowel. The authors present the ca...
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COVID-19 and ECT - a Victorian perspective
OBJECTIVES: (i) to describe the operational strategies implemented to practise electroconvulsive therapy (ECT) safely, and (ii) to explore the effect of the lockdown and operational strategies on the characteristics of patients who received ECT during the initial 6 months of the COVID-19 lockdown. METHODS: At first, th...
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The Relationship between Suicidality and Socio-Demographic Variables, Physical Disorders, and Psychiatric Disorders: Results from the Singapore Mental Health Study 2016
Suicidality encompasses suicidal ideation, plans, and attempts. This paper aims to establish associations between suicidality and sociodemographic variables, physical disorders, and psychiatric disorders. The Singapore Mental Health Study 2016 was a population-level epidemiological survey, which determined the prevalen...
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Knowledge, Anxiety, Depression, and Sleep Quality Among Medical Staff in Central South Areas of China During the Break of COVID-19: Does the Level of Hospitals Make a Difference?
Purpose: To evaluate the knowledge, anxiety, depression, and sleep quality toward COVID-19 among Chinese medical staff from tertiary and basic-level hospitals in central south areas of China. Method: A structured questionnaire was composed of Demographic and clinical characteristics of medical staff, Knowledge toward C...
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Cyber-Physical Systems Security: Limitations, Issues and Future Trends
Typically, Cyber-Physical Systems (CPS) involve various interconnected systems, which can monitor and manipulate real objects and processes. They are closely related to Internet of Things (IoT) systems, except that CPS focuses on the interaction between physical, networking and computation processes. Their integration ...
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Vietnamese living habits, wellbeing and working adaptation in face of COVID-19's strictest lockdown
Purpose This study explores the impacts of COVID-19's strictest lockdown on Vietnamese citizens' living habits, wellbeing and work-from-home effectiveness. Design/methodology/approach The study uses a survey questionnaire to gather relevant data from Vietnamese adults during the most recent, strictest lockdown in their...
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Using Andersen’s model of health care utilization to assess factors associated with COVID-19 testing among adults in nine low-and middle-income countries: an online survey
BACKGROUND: This study aimed to investigate, using Andersen’s model of health care utilization, factors associated with COVID-19 testing among adults in nine low- and middle- income countries. METHODS: In between 10 December 2020 and 9 February 2021, an online survey was organized in nine low- and middle-income countri...
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SARS-CoV-2 encephalitis is a cytokine release syndrome: evidences from cerebrospinal fluid analyses
BACKGROUND: Recent findings indicated that SARS-CoV-2 related neurological manifestations involve cytokine release syndrome along with endothelial activation, blood brain barrier dysfunction, and immune‐mediated mechanisms. Very few studies have fully investigated the CSF correlates of SARS-CoV-2 encephalitis. METHODS:...
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Lessons and Recommendations from a Pentobarbital Shortage: US and Canada 2021
SIMPLE SUMMARY: Pentobarbital sodium is a common animal euthanasia drug in the United States and Canada, as well as in other countries with access to it. A shortage of the drug in 2021 created a dilemma for those needing to perform the euthanasia procedure in animals facing negative welfare conditions. The reason for t...
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Multinational Study to Assess Stress Levels Among the Health Care Workers of Radiation Oncology Community at the Outset of the COVID-19 Pandemic
PURPOSE: To evaluate stress levels among the health care workers (HCWs) of the radiation oncology community in Asian countries. METHODS: HCWs of the radiation oncology departments from 29 tertiary cancer care centers of Bangladesh, India, Indonesia and Nepal were studied from May 2020 to July 2020. A total of 758 eligi...
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Spatiotemporal Variation of Air Quality (PM and NO2) in Southern Paris during COVID-19 Lockdown Periods
In urban areas, road transportation is the main source of pollutants, and weather impacts spatiotemporal variation of air quality. In this paper, we demonstrate the spatiotemporal variabilities of particulate matter (PM10 and PM2.5) and NO2 in the south of Paris, with an emphasis on the comparison of air pollutant leve...
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Effects of COVID-19-related life changes on mental health in Syrian refugees in Turkey
BACKGROUND: Mental disorders are currently the greatest global health burden. The coronavirus diseases 2019 (COVID-19) pandemic is having an adverse impact on people's mental health, particularly in vulnerable populations, such as refugees. AIMS: The present study was designed to examine the association between COVID-1...
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Athletes and Coaches through the COVID-19 Pandemic: A Qualitative View of Goal Management
Since the end of 2019 and throughout 2020, the world has been devastated by the COVID-19 pandemic. The sports world suddenly had to deal with a massive reorganization of events with important implications for the physical and psychological preparation of athletes and coaches. The purpose of this study was to explore ho...
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Neural-IR-Explorer: A Content-Focused Tool to Explore Neural Re-ranking Results
In this paper we look beyond metrics-based evaluation of Information Retrieval systems, to explore the reasons behind ranking results. We present the content-focused Neural-IR-Explorer, which empowers users to browse through retrieval results and inspect the inner workings and fine-grained results of neural re-ranking ...
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High-resolution CT (HRCT) chest findings in PCR positive patients of covid-19 at combined military hospital Rawalpindi
Objective: To study High resolution computed tomography chest findings in polymerase chain reaction (PCR) positive patients of COVID-19. Study Design: Cross sectional study. Place and Duration of Study: Combined Military Hospital Rawalpindi, from May to Jun 2020. Methodology: Study included high resolution computed tom...
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Phonon-Induced Relocation of Valence Charge in Boron Nitride Observed by Ultrafast X-Ray Diffraction
The impact of coherent phonon excitations on the valence charge distribution in cubic boron nitride is mapped by femtosecond x-ray powder diffraction. Zone-edge transverse acoustic (TA) two-phonon excitations generated by an impulsive Raman process induce a steplike increase of diffracted x-ray intensity. Charge densit...
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COVIDOM : une expérience de télémédecine unique pour la gestion du COVID-19
Introduction Afin d’éviter l’engorgement du système de soin et de soulager les praticiens ainsi que d’éviter les contaminations hospitalières, le dispositif de télésuivi COVIDOM a été mis en place en urgence à l’échelle de l’Ile de France. Il permet le suivi des patients à domicile atteint du COVID-19. Il s’agit d’une ...
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Local Factors and the Spread of COVID-19 in Germany
Due to the high level of infectivity the spread of COVID-19 is closely related to the number of daily face-to-face contacts between humans Whereas the extent i
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Globalization and Regionalization: Empirical Evidence from Itinerary Structure and Port Organization of World Cruise of Cunard
Cruise tourism is an obviously global industry in different dimensions From a geographical perspective, cruise ships are mobile and capable of being repositioned at a company’s notice, which forms the inherent basis for its global spatial layout As a branch of the cruise industry, the world cruise is clearly globalizin...
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Curvature effects in charge-regulated lipid bilayers
We formulate a theory of electrostatic interactions in lipid bilayer membranes where both monolayer leaflets contain dissociable moieties that are subject to charge regulation. We specifically investigate the coupling between membrane curvature and charge regulation of a lipid bilayer vesicle using both the linear Deby...
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Elevated fasting blood glucose within the first week of hospitalization was associated with progression to severe illness of COVID-19 in patients with preexisting diabetes: A multicenter observational study
Highlights Fasting blood glucose < 10 mmol/L was proposed as a target of glycemic control during the first week of hospitalization in patients with preexisting diabetes. Poor HbA1c levels prior to coronavirus disease 2019 (COVID-19) might not be associated with severity among patients with preexisting diabetes. Mean bl...
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Innovation in an authoritarian society: China during the pandemic crisis
Purpose: This paper aims to understand the role of government played in the innovation process during the social crisis, and to investigate the innovation activities of the authoritarian state when dealing with social crisis Design/methodology/approach: Secondary data pertaining to eight impactful technological innovat...
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Countering social stigma and discrimination during the COVID-19 pandemic through solidarity
A recent article highlighted the difference between the attitude and mental health of domestic and overseas Chinese college students. It suggests that this difference is due to the social stigma and discrimination inflicted on overseas Chinese students. In this correspondence, the author proposes solidarity, analogous ...
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Economic thoughts on COVID-19 for Canadian food processors
In this paper, I explore the potential effects of the COVID-19 pandemic on Canadian food processors. First, COVID-19 may have an impact on food processing economic activities because of supply and demand shocks. Second, the impact of COVID-19 on food processing may depend on the type of products and the size of the pro...
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Effectiveness of lifestyle modification on quality of life among uncontrolled diabetics and hypertensives in India – Community based intervention study
BACKGROUND: Diabetes and hypertension contribute to more than half of morbidity, mortality and years lived with disability in developing countries like India. It impacts the quality of life (QoL) of patients and their family. Management of these diseases is in infancy and emphasis is laid on pharmacological interventio...
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Recomendaciones para el manejo de la faringoamigdalitis aguda del adulto()
Acute pharyngitis in adults is one of the most common infectious diseases seen in general practitioners’ consultations. Viral aetiology is the most common. Among bacterial causes, the main agent is Streptococcus pyogenes or group A β-haemolytic streptococcus (GABHS), which causes 5%-30% of the episodes. In the diagnost...
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Effectiveness of isolation, testing, contact tracing and physical distancing on reducing transmission of SARS-CoV-2 in different settings
Isolation of symptomatic cases and tracing of contacts has been used as an early COVID-19 containment measure in many countries, with additional physical distancing measures also introduced as outbreaks have grown. To maintain control of infection while also reducing disruption to populations, there is a need to unders...
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SARS-CoV-2 – Wie kann und muss sich medizinisches Personal schützen?
The SARS-CoV‑2 pandemic represents a great challenge worldwide not only under the aspect of treatment but also of prevention. The infection curve could be flattened by the rapid implementation of simple distance and hygiene measures. In order to ensure current and future patient care in conjunction with protection of m...
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Alemtuzumab in Covid era
BACKGROUND: The SARS-CoV-2 pandemic impact on people with Multiple Sclerosis (pwMS) continues to worry. The disease modifying therapies in pwMS can add a more severe risk of infection when compared to the general population. Alemtuzumab is an anti-CD52 monoclonal antibody and it is one of the most immunosuppressive dru...
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Childhood-onset systemic lupus erythematosus and immune thrombocytopenia: Prevalence and risk factors
BACKGROUND: There are few studies examining the prevalence and clinical risk factors for subsequent systemic lupus erythematosus (SLE) development after long-term follow-up in childhood immune thrombocytopenia (ITP). The aims of this study were to evaluate the prevalence and risk factors for subsequent SLE development ...
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The Pandemic of Productivity: A Narrative Inquiry into the Value of Leisure Time
This study explored narratives derived from in-depth interviews to demonstrate how an increase in leisure time could positively affect both our subjective well-being, through a better balance of work and "self", and the environment, through a change in consumption practices. Firstly, the analysis of the interviews prov...
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SARS-CoV-2 antibody persistence in COVID-19 convalescent plasma donors: Dependency on assay format and applicability to serosurveillance
BACKGROUND: Antibody response duration following severe acute respiratory syndrome coronavirus 2 infection tends to be variable and depends on severity of disease and method of detection. STUDY DESIGN AND METHODS: COVID-19 convalescent plasma from 18 donors was collected longitudinally for a maximum of 63-129 days foll...
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Fetal Gallstones in a Newborn after Maternal COVID-19 Infection
Fetal gallstones are rare incidental findings on ultrasound during pregnancy. We describe a newborn girl with gallstones that was born to a mother who had COVID-19 infection during her last trimester. The baby remained asymptomatic, and the stones resolved spontaneously without any treatment or complications within six...
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Comparison of the effects of platelet-rich or growth factor-rich plasma on intestinal anastomosis healing in pigs.
BACKGROUND The use of autologous platelet-rich plasma (PRP) and plasma rich in growth factors (PRGF) has been proposed for the treatment of several acute and chronic syndromes, such as corneal epithelial defects and dry eye syndrome, gum bleeding during oral surgery, and in orthopaedic surgery. We hypothesized that PRG...
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Management of hepatitis B virus reactivation due to treatment of COVID-19
The world has made significant progress in developing novel treatments for COVID-19 since the pandemic began. Some treatments target the patient’s dysregulated inflammatory response during COVID-19 infection and may cause hepatitis B reactivation (HBVr) in patients with current or past hepatitis B virus (HBV) infection...
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A computational methodology to diagnose sequence-variant dynamic perturbations by comparing atomic protein structures
MOTIVATION: The objective is to diagnose dynamics perturbations caused by amino acid mutations as prerequisite to assess protein functional health or drug failure, simply using network models of protein X-ray structures. RESULTS: We find that the differences in the allocation of the atomic interactions of each amino ac...
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Impact of Cannabinoid Compounds on Skin Cancer
SIMPLE SUMMARY: Recent research has suggested that the endocannabinoid system offers several pharmacotherapeutic targets for drug administration as new options for the treatment and prophylaxis of skin cancer. This review focused on the anticarcinogenic mechanisms of cannabinoids at the different levels of skin cancer ...
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Technology-based counselling in dementia (TeCoDem): study protocol of a mixed-methods systematic review with qualitative comparative analysis and meta-analysis
INTRODUCTION: Information technology can enhance timely and individual support for people with dementia and informal carers. There is some evidence that people with dementia and informal carers would benefit from technology-based counselling. However, it remains unclear which features of those interventions relate to b...
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The Economic Cost of Burnout in Veterinary Medicine
The purpose of this study is to estimate the economic cost of burnout in the veterinary profession and highlight the financial reasons why the industry should address the burnout crisis from an organizational perspective. Using data from 5,786 associate veterinarians in private practice, information was obtained using ...
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Good practices recommendations from the Brazilian Society of Nephrology to Peritoneal Dialysis Services related to the new coronavirus (Covid-19) epidemic
Considering the new coronavirus epidemic (Covid-19), the Brazilian Society of Nephrology, represented by the Peritoneal Steering Committee, in agreement with the and the Dialysis Department, developed a series of recommendations for good clinical practices for peritoneal dialysis (PD) clinics, to be considered during t...
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Insights From Veterinary Disciplinary Actions in California 2017–2019
There is increasing concern within the veterinary medical community (veterinarians and veterinary students) that disgruntled clients are unfairly leveraging various legal tools against veterinarians. Clinical veterinarians and veterinary students should be aware of the most common types of problems arising within the c...
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Principles and Algorithms for Forecasting Groups of Time Series: Locality and Globality
Forecasting groups of time series is of increasing practical importance, e.g. forecasting the demand for multiple products offered by a retailer or server loads within a data center. The local approach to this problem considers each time series separately and fits a function or model to each series. The global approach...
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Genome-wide analysis of 10664 SARS-CoV-2 genomes to identify virus strains in 73 countries based on single nucleotide polymorphism
Since the onslaught of SARS-CoV-2, the research community has been searching for a vaccine to fight against this virus. However, during this period, the virus has mutated to adapt to the different environmental conditions in the world and made the task of vaccine design more challenging. In this situation, the identifi...
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Antibody rapid test positive health care workers at a german university hospital: First wave characteristics
Background: Freiburg was among the most heavily affected German cities during the first wave of Sars-Cov-2 infections in spring 2020. Consequently, the University Medical Center Freiburg was one of the first hospitals in Germany to treat Covid19 patients. Objectives: To assess the proportion and characteristics of heal...
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Factors associated with nosocomial SARS-CoV transmission among healthcare workers in Hanoi, Vietnam, 2003
BACKGROUND: In March of 2003, an outbreak of Severe Acute Respiratory Syndrome (SARS) occurred in Northern Vietnam. This outbreak began when a traveler arriving from Hong Kong sought medical care at a small hospital (Hospital A) in Hanoi, initiating a serious and substantial transmission event within the hospital, and ...
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Non-Central Limit Theorem Statistical Analysis for the"Long-tailed"Internet Society
This article presents a statistical analysis method and introduces the corresponding software package"tailstat,"which is believed to be widely applicable to today's internet society. The proposed method facilitates statistical analyses with small sample sets from given populations, which render the central limit theore...
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Construct Dimensionality of Personal Energy at Work and Its Relationship with Health, Absenteeism and Productivity
Personal energy at work has become a popular topic among HRM scholars and practitioners because it has proven to impact performance. Based on the outcomes of previous research and the call for further exploration of the construct of personal energy at work, we executed this quantitative study. We explored the factor st...
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Addressing students’ emotional needs during the COVID-19 pandemic: a perspective on text versus video feedback in online environments
This paper reflects on the findings of Borup et al. (Educ Technol Res Dev 63:161–184, 2015) regarding the efficiency and affect of text and video feedback in the context of the rapid shift to online education due to the COVID-19 pandemic. Based on reports of diminished mental wellness, increased depression, and anxiety...
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Knowledge, Attitudes, and Practices Regarding COVID-19 Among Health Care Workers in Public Health Facilities in Eastern Ethiopia: Cross-sectional Survey Study
BACKGROUND: On March 13, 2020, Ethiopia reported the first confirmed case of COVID-19 in Addis Ababa. COVID-19 is likely to overwhelm an already-fragile health care delivery system and reduce the availability of essential health services. This analysis of data from the Somali Region of Eastern Ethiopia on health care w...
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Refundable income annuities: Feasibility of money-back guarantees
Refundable income annuities (IA), such as cash-refund and instalment-refund, differ in material ways from the life-only version beloved by economists. In addition to lifetime income they guarantee the annuitant or beneficiary will receive their money back albeit slowly over time. We document that refundable IAs now rep...
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Epidemiology and Treatment Options for COVID-19: A Review.
The Coronavirus disease 19 (COVID-19) is a highly transmittable and pathogenic viral infection caused by severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2), which emerged in Wuhan, China and spread around the world. As of 19 June 2020 data from the World Health Organization (WHO) have shown that more than 845...
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SARS-CoV-2 (COVID-19): Zoonotic origin and susceptibility of domestic and wild animals
Coronaviruses (CoVs) are responsible for causing economically significant diseases both in animals and humans. The Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), causing Coronavirus Diseases (COVID-19), outbreak has become the first pandemic of the 21st century and is the deadliest pandemic after the 191...
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The effects of the first national lockdown in England on geographical inequalities in the evolution of COVID-19 case rates: An ecological study
Background Socio-economic inequalities in COVID-19 case rates have been noted worldwide. Previous studies have compared case rates over set phases. There has been no analysis of how inequalities in cases changed overtime and were shaped by national mitigation strategies (e.g. lock downs). This paper provides the first ...
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Bacillus Calmette-Guerin vaccination Policy and Consumption of Ammonium Chloride-Enriched Confectioneries May Be Factors Reducing COVID-19 Death Rates in Europe
BACKGROUNDThe 2019 severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic continued into 2020, and the coronavirus disease-2019 (COVID-19) associated death toll increased OBJECTIVESTo analyze COVID-19 death rates in European countries or regions to determine whether there was a significant association be...
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Limitations of posterior spinal fusion to L5 for flaccid neuromuscular scoliosis focusing on pelvic obliquity.
STUDY DESIGN Retrospective comparison based on the degree of pelvic obliquity (PO). PURPOSE To assess the controversial indications for and limitations of ending the instrumentation for posterior spinal fusion (PSF) at L5 in patients with flaccid neuromuscular scoliosis (fNMS). METHODS We reviewed the cases of 45 patie...
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Performing gynecologic cancer surgery during the COVID-19 pandemic in Turkey: A multicenter retrospective observational study
OBJECTIVE: To report the perioperative outcomes of 200 patients with gynecologic cancer who underwent surgery during the Novel Coronavirus Disease (COVID-19) pandemic and the safety of surgical approach. METHODS: Data of patients operated between March 10 and May 20, 2020, were collected retrospectively. Data were stat...
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Antiviral Potential of Nanoparticles-Can Nanoparticles Fight Against Coronaviruses?
Infectious diseases account for more than 20% of global mortality and viruses are responsible for about one-third of these deaths. Highly infectious viral diseases such as severe acute respiratory (SARS), Middle East respiratory syndrome (MERS) and coronavirus disease (COVID-19) are emerging more frequently and their w...
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Organizing Pneumonias
Organizing pneumonia is a particular type of inflammatory and reparative reaction of the lung parenchyma characterized by fibroblast proliferation in the distal airspaces with overall preservation of the lung architecture. When microscopic, it is an asymptomatic and nonspecific reaction of little clinical significance ...
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Olfactory Dysfunction in Coronavirus Disease 2019 Patients: Observational Cohort Study and Systematic Review
Background: Olfactory dysfunction (OD) has been reported in coronavirus disease 2019 (COVID-19). However, there are knowledge gaps about the severity, prevalence, etiology, and duration of OD in COVID-19 patients. Methods: Olfactory function was assessed in all participants using questionnaires and the butanol threshol...
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A luciferase immunosorbent assay for quantitative detection of IgG antibodies against SARS-CoV-2 nucleoprotein
In this study, we developed and evaluated a luciferase immunosorbent assay (LISA) for quantitative detection of IgG antibody against SARS-CoV-2 nucleoprotein (NP). Anti-SARS-CoV-2 NP antibody in serum or plasma samples was captured by protein G-coated microtiter plate and detected using the crude cell lysates expressin...
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A Hybridized Stochastic SIR-Vasiček Model in Evaluating a Pandemic Emergency Financing Facility
In the context of the present global health crisis, we examine the design and valuation of a pandemic emergency financing facility (PEFF) akin to a catastrophe (CAT) bond. While a CAT bond typically enables fund generation to the insurers and re-insurers after a disaster happens, a PEFF or pandemic bond's payout is lin...
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LncRNA FGD5-AS1 promotes the malignant phenotypes of ovarian cancer cells via targeting miR-142-5p.
Long non-coding RNAs (lncRNAs) have been reported to participate in regulating gene expression and are related to tumor progression. FGD5 antisense RNA 1 (FGD5-AS1) facilitates the progression of various tumors. However, the expression and function of FGD5-AS1 in ovarian cancer (OC) and its mechanism of action are not ...
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COVID-19 during pregnancy: an overview of maternal characteristics, clinical symptoms, maternal and neonatal outcomes of 10,996 cases described in 15 countries
The objective of this review was to identify the most significant studies reporting on COVID-19 during pregnancy and to provide an overview of SARS-CoV-2 infection in pregnant women and perinatal outcomes. Eligibility criteria included all reports, reviews; case series with more than 100 individuals and that reported a...
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The Research of SEIJR Model with Time-Delay based on 2019-nCov
A global epidemic disease known as the novel coronavirus (2019-nCov) had seriously hit the most area around the whole world causing unpredictable loss of manpower and finance during the past one year. Modeling the spread and development of infectious diseases represented by new Coronavirus has become an important part ...
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