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Please summerize the given abstract to a title
INTRODUCTION: Infection with the new coronavirus responsible for Severe Acute Respiratory Syndrome (SARS-CoV-2) continues to spread worldwide. In Brazil, there are already more than 230 thousand dead, many of these older adults. OBJECTIVE: To present the clinical characteristics of older Brazilian adults infected by CO...
Clinical characteristics of 1544 Brazilians aged 60 years and over with laboratory evidence for SARS-CoV-2
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OBJECTIVE: To compare maternal and perinatal outcomes between randomized trials and observational studies in which conservative management was performed for more than 48 h in patients with early-onset severe preeclampsia. METHODOLOGY: We searched PubMed, LILACS, Cochrane and Google Scholar. The studies were divided in ...
Conservative management of early-onset severe preeclampsia: comparison between randomized and observational studies a systematic review
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Background:In recent years, an integrated programme of vector control, screening and treatment of gambiense human African trypanosomiasis (gHAT) infections has led to a rapid decline in cases in the Mandoul disease focus of Chad. In this study, we assess whether elimination of transmission has already been achieved in ...
Update of transmission modelling and projections of gambiense human African trypanosomiasis in the Mandoul focus, Chad
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Microanatomy of the vast majority of human organs at birth is characterized by marked differences as compared to adult organs, regarding their architecture and the cell types detectable at histology. In preterm neonates, these differences are even more evident, due to the lower level of organ maturation and to ongoing ...
Stem/progenitor cells in fetuses and newborns: overview of immunohistochemical markers.
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The current COVID-19 pandemic has increased the use of alcohol based hand sanitisers globally. These available alcohol based sanitisers cannot provide an antibacterial effect for an extended period of time, after the evaporation of ethanol. Hence, the need for a sanitiser with an anti-microbial activity combined with a...
Synthesis and characterization of a nano-formulation for long lasting sterilization effect
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The Covid-19 outbreak of 2020 has required many governments to develop mathematical-statistical models of the outbreak for policy and planning purposes. This work provides a tutorial on building a compartmental model using Susceptibles, Exposed, Infected, Recovered and Deaths status through time. A Bayesian Framework i...
SEIRD Model for Qatar Covid-19 Outbreak: A Case Study
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The coronavirus disease 2019 (COVID-19) pandemic is a global crisis, with devastating health, business and social impacts. Vaccination is a safe, simple, and effective way of protecting a person against COVID-19. By the end of August 2021, only 24.6% of the world population has received two doses of a COVID-19 vaccine....
COVID-19 vaccines: Current evidence and considerations
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This study aimed to investigate the relationship between socioeconomic status and COVID‐19 mortality in Iran. We performed a retrospective cohort study on data from the hospitalised COVID‐19 patients in Qazvin. We collected data on education, self‐reported socioeconomic status, and location of residence as a proxy for ...
Decomposition of socioeconomic inequality in COVID‐19 mortality in Iran: A retrospective cohort study
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The COVID-19 pandemic has significantly disrupted the delivery of healthcare services, including oncology. To ensure continuity of cancer genetic counseling at a large academic medical center while also promoting the safety of patients and staff, our team transitioned to fully remote telephone genetic counseling and te...
Transition to telephone genetic counseling services during the COVID-19 pandemic
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OBJECTIVE: This randomised controlled trial (RCT) aimed to investigate the effects of a simple cognitive task intervention on intrusive memories ("flashbacks") and associated symptoms following a traumatic event. Patients presenting to a Swedish emergency department (ED) soon after a traumatic event were randomly alloc...
A simple cognitive task intervention to prevent intrusive memories after trauma in patients in the Emergency Department: A randomized controlled trial terminated due to COVID-19
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INTRODUCTION: It is unclear whether smokers are more vulnerable to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. This study aimed to evaluate the association between smoking and the risk of SARS-CoV-2 infection. METHODS: A matched case-control study was conducted using a large nationwide datab...
Smoking and the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
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The nucleolus is a dynamic subnuclear structure involved in ribosome subunit biogenesis, cell cycle control and mediating responses to cell stress, among other functions. While many different viruses target proteins to the nucleolus and recruit nucleolar proteins to facilitate virus replication, the effect of infection...
Changes in nucleolar morphology and proteins during infection with the coronavirus infectious bronchitis virus
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The 3C-like proteinase (3CL(pro)) of severe acute respiratory syndrome (SARS) coronavirus is a key target for structure-based drug design against this viral infection. The enzyme recognizes peptide substrates with a glutamine residue at the P1 site. A series of keto-glutamine analogues with a phthalhydrazido group at t...
Synthesis and evaluation of keto-glutamine analogues as potent inhibitors of severe acute respiratory syndrome 3CLpro.
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Purpose>This paper explores the challenges of food security from source to consumption of agri-food value chain by considering urban–rural linkages in city region food systems (CRFSs) and proposes a strategic framework for CRFS identifying strategies to promote urban–rural linkages among multiple stakeholders.Design/me...
Challenges of agri-food supply in city region food systems: an emerging economy perspective
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BACKGROUND AND AIMS: Vaccine hesitancy is an ongoing major challenge. We aimed to assess the uptake and hesitancy of the COVID-19 vaccination. METHODS: A short online survey was posted between April 12 to July 31, 2021 targeted at health and social care workers (HCWs) across the globe. RESULTS: 275 from 37 countries re...
COVID-19 vaccine uptake and hesitancy opinions from frontline health care and social care workers: Survey data from 37 countries
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Introduction: As COVID-19 develops around the world, numerous publications have described the psychiatric consequences of this pandemic Although clinicians and healthcare systems are mainly focused on managing critically ill patients in an attempt to limit the number of casualties, psychiatric disease burden is increas...
Domestic violence and substance abuse during COVID19: A systematic review
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The youth sport system in the United States is not achieving its full potential. There is a need to reimagine this system in ways that are evidence-based, innovative, and coordinated to best safeguard and promote the well-being of young people. The purpose of this expert commentary, composed by the President's Council ...
Reimagining the Youth Sport System across the United States: A Commentary from the 2020-2021 President's Council on Sports, Fitness & Nutrition Science Board
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Spinal cord injury (SCI) can cause severe trauma to the central nervous system. Resveratrol has been widely studied for several of its medicinal properties, including anti-inflammatory, anti-aging and anti-oxidative effects. The regulation of SIRT-1 is thought to be related to the effects of resveratrol. As a downstrea...
Resveratrol inhibits inflammation after spinal cord injury via SIRT-1/NF-κB signaling pathway.
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Frontline COVID workers (doctors, nurses, paramedics, law enforcement officers, social workers) have been especially impacted by the pandemic (1). Stigma and fear of job loss often prevent help seeking (2,3). Evidence-based interventions exist but can be hard to navigate, limiting or delaying their timely uptake (4,5)....
Using a Chatbot to Address Psychological Distress Among First Responders
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It has been found that a domain composed of 330 amino acids of the N terminus of murine coronavirus spike protein [S1N(330)] is involved in receptor-binding activity (H. Kubo, Y.K. Yamada, and F. Taguchi, J. Virol. 68:5403-5410, 1994). To delineate the amino acid sequences involved in receptor-binding activity, we have...
Analysis of the receptor-binding site of murine coronavirus spike protein.
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Non-coding RNAs (ncRNAs) are key regulators of post-transcriptional gene expression in prokaryotic and eukaryotic organisms. These molecules can interact with mRNAs or proteins, affecting a variety of cellular functions. Emerging evidence shows that intra/inter-species and trans-kingdom regulation can also be achieved ...
Extracellular RNAs in Bacterial Infections: From Emerging Key Players on Host-Pathogen Interactions to Exploitable Biomarkers and Therapeutic Targets
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The essay analyses the COVID-19 impact on contracts, identifies the renegotiation as possible remedy, suitable only if combined with specific extrajudicial procedures that make it effective It focuses also on energy poverty in the emergencies regulatory framework © 2020 Ibero-American Law Institute All rights reserved
Economic vulnerability between emergency and contract law
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Diarrhea outbreaks in pig farms have raised major concerns in Europe and USA, as they can lead to dramatic pig losses. During a suspected outbreak in Belgium of porcine epidemic diarrhea virus (PEDV), we performed viral metagenomics to assess other potential viral pathogens. Although PEDV was detected, its low abundanc...
Identification of an enterovirus recombinant with a torovirus-like gene insertion during a diarrhea outbreak in fattening pigs
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Viruses are ubiquitous in the environment. While many impart no deleterious effects on their hosts, several are major pathogens. This risk of pathogenicity, alongside the fact that many viruses can rapidly mutate highlights the need for suitable, rapid diagnostic measures. This review provides a critical analysis of wi...
Virus Detection: A Review of the Current and Emerging Molecular and Immunological Methods
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Brucellosis is a zoonotic infection that is usually transmitted from cattle to humans through ingestion of animal milk, direct contact with animal parts, or inhalation of aerosolized particles. In Korea, brucellosis seem to be transmitted through close contact with blood, fetus, urine, and placenta of domestic cow that...
An Imported Case of Brucella melitensis Infection in South Korea
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Résumé La prise en charge des pathologies du sommeil a été fortement impactée par l’épidémie de COVID-19. La reprise des soins auprès de la population, à la sortie du confinement, va nécessiter des précautions visant à limiter les risques de contamination des patients et des soignants. L’Association Française du Sommei...
Modalités pratiques de prise en charge des patients apnéiques par l’ORL durant l’épidémie de COVID-19
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Background: Acute respiratory illness caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) involved the whole globe within no time Various studies published globally have shown variable severity of disease and mortality The objective of our study was to describe clinical and epidemiological characteri...
Clinical and virological course of SARS-CoV 2 infected patients in a tertiary care hospital in Pakistan
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With the emergence of new SARS-CoV-2 variants and the acquisition of novel mutations in exiting lineages, the need to implement methods capable of monitoring viral dynamics arises. We report the emergence and spread of a new SARS-CoV-2 variant within B.1.575 lineage containing the E484K mutation in the spike protein (n...
Emergence of SARS-CoV-2 variant B.1.575.2 containing the E484K mutation in the spike protein in Pamplona (Spain) May-June 2021
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This paper studies the sample complexity (aka number of comparisons) bounds for the active best-$k$ items selection from pairwise comparisons. From a given set of items, the learner can make pairwise comparisons on every pair of items, and each comparison returns an independent noisy result about the preferred item. At...
The Sample Complexity of Best-$k$ Items Selection from Pairwise Comparisons
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Anterior iliopsoas impingement and tendinitis is a poorly understood and likely underrecognized cause of groin pain and functional disability after total hip arthroplasty. The patient history and physical examination findings are usually only suggestive, and the symptoms frequently subtle. The diagnosis may be confirme...
Anterior iliopsoas impingement and tendinitis after total hip arthroplasty.
Please summerize the given abstract to a title
OBJECTIVE: To study maternal anxiety in pregnant women without comorbidities in the context of the COVID-19 outbreak in Brazil and to study maternal knowledge and concerns about the pandemic. METHODS: This is a secondary analysis from a national multicenter cross-sectional study performed in 10 cities, from June to Aug...
Increased Risk for Maternal Anxiety during the COVID-19 Outbreak in Brazil among Pregnant Women without Comorbidities
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Allergic rhinitis (AR) is one of the most common allergic diseases in children and it can lead to physical and mental health problems. Traditional Chinese medicine (TCM) plays an important role in understanding the phenotypes and treatment of AR. However, there are currently no normative clinical practice guidelines (C...
Clinical practice guidelines for the treatment of allergic rhinitis in children with traditional Chinese medicine.
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Background/Purpose In 2003, the severe acute respiratory syndrome (SARS) outbreak resulted in 8096 probable cases and 774 deaths in 26 countries. The purpose of this study was to explore the effect of the SARS outbreak on hospitalization for chronic ambulatory-care-sensitive conditions (ACSCs) in Taiwan. Methods We app...
Hospitalization for Ambulatory-care-sensitive Conditions in Taiwan Following the SARS Outbreak: A Population-based Interrupted Time Series Study
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Forensic laboratories are required to have analytical tools to confidently differentiate illegal substances such as marijuana from legal products (i.e., industrial hemp). The Achilles heel of industrial hemp is its association with marijuana. Industrial hemp from the Cannabis sativa L. plant is reported to be one of th...
Bridging Disciplines: Applications of Forensic Science and Industrial Hemp
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Both objective and perceived social isolations were associated with future cognitive decline and increase risk of Alzheimer’s disease (AD). However, the impacts of perceived social isolation depending on different clinical stages of AD have not been elucidated. The aim of this study was to investigate the influence of ...
Perceived social isolation is correlated with brain structure and cognitive trajectory in Alzheimer’s disease
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BACKGROUND Based on the Global Trends report from the United Nations High Commissioner for Refugee, in high-income countries, there are 2.7 refuges per 1000 national population, girls and women account for nearly 50% of this refuge population. In these high-income countries, compared with the general population refuge ...
Barriers and facilitators to access mental health services among refugee women in high-income countries: a systematic review.
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SARS-CoV-2 causes a severe pneumonia (COVID-19) that affects essentially elderly people. In COVID-19, macrophage infiltration into the lung causes a rapid and intense cytokine storm leading finally to a multi-organ failure and death. Comorbidities such as metabolic syndrome, obesity, type 2 diabetes, lung and cardiovas...
Age-related mitochondrial dysfunction as a key factor in COVID-19 disease
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The demands of high-performance sport are exacerbated during the lead up to the Major Games (i.e., Paralympics). The purpose of this study was to better understand the challenges experienced and strategies utilized by Australian athletes (n = 7) and coaches (n = 5) preparing for the Tokyo Paralympic Games using semi-st...
Challenges and stresses experienced by athletes and coaches leading up to the Paralympic Games
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We analyzed 221 COVID-19 cases identified between June 2020 and January 2021 in 6,074 individuals screened for IgG antibodies in May 2020, representing 77% of residents of five Italian municipalities. The adjusted relative risk of developing symptomatic infection in SARS-COV-2 seropositive participants was 0.055 (95%CI...
The risk of symptomatic infection during a second COVID-19 wave, in SARS-CoV-2 seropositive individuals
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Validation of key analytical and functional performance characteristics of in vitro immunogenicity risk assessment assays increases our confidence in utilizing them for screening biotherapeutics. Herein, we present a fit-for-purpose (FFP) validation of a dendritic cell (DC) activation assay designed to assess the immun...
Fit-for-Purpose Validation and Establishment of Assay Acceptance and Reporting Criteria of Dendritic Cell Activation Assay Contributing to the Assessment of Immunogenicity Risk.
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PURPOSE: Cholangiocarcinoma (CCA) is a malignant tumor with a high incidence. The therapeutic effect of conventional chemotherapy and radiotherapy is not obvious. Photodynamic therapy (PDT) is an ideal modality to fight cancer, and the nature of photosensitizer limits its application in clinical therapy. The aim of thi...
A Study on Mesoporous Silica Loaded With Novel Photosensitizers HCE6 and Oxaliplatin for the Treatment of Cholangiocarcinoma
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As the COVID-19 virus spread across the globe, sport leagues and mega-events succumbed to the pandemic, shuttering even the most high-profile activities, including the 2020 Tokyo Olympics. As the global crisis deepened and competitions returned in modified formats, sport’s political uses – viewed widely – became increa...
Sport in Times of Turmoil: Political Uses of Sport in Global Crises
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During lairage at slaughter plants, cattle can be exposed to extreme heat conditions from pen densities and holding pen microclimates. While research outlining heat mitigation strategies used in other sectors of the beef supply chain is available, there is no published data on the use of heat mitigation strategies at s...
Characterizing heat mitigation strategies utilized by beef processors in the United States
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INTRODUCTION: Since 2010, General Ophthalmic Services (GOS) legislation and Independent Prescribing (IP) enable community optometrists to manage primary eye conditions. No studies have assessed the effect of IP. We wished to determine the distribution of IP optometrists and associated hospital referral rates across Sco...
Assessing the effect of Independent Prescribing for community optometrists and referral rates to Hospital Eye Services in Scotland
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RNA nanotechnology is the bottom-up self-assembly of nanometer-scale architectures, resembling LEGOs, composed mainly of RNA. The ideal building material should be (1) versatile and controllable in shape and stoichiometry, (2) spontaneously self-assemble, and (3) thermodynamically, chemically, and enzymatically stable ...
Thermostability, Tunability, and Tenacity of RNA as Rubbery Anionic Polymeric Materials in Nanotechnology and Nanomedicine-Specific Cancer Targeting with Undetectable Toxicity
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An inactivated vaccine based on the Sal. abortus equi BN-12 strain with the Bac. subtilis TNP-3 strain filtrate used as immunomodulator has been developed in order to prevent salmonella-induced equine abortion. Preclinical and clinical trials with the white mice and the horses, respectively, are carried out. The lack o...
Developmental Results of a Vaccine against Salmonella-Induced Equine Abortion
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BACKGROUND Strategy to inhibit the virus replication is an attractive means in combating SARS-CoV-2 infection. OBJECTIVE We studied phyto-compounds from Strychnos nux-vomica (a poisonous plant) against SARS-CoV-2 RNA-dependent RNA polymerase by computational methods. METHOD Molecular docking, molecular dynamics (MD) si...
Phyto-compounds from a rather poisonous plant, Strychnos nux-vomica, show high potency against SARS-CoV-2 RNA-dependent RNA polymerase.
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COVID-19 has caused a global pandemic since December 2019 It has impacted not only the wellbeing of human society but also has been damaging to the global economy This has imposed severe threats and challenges on businesses The British government has launched aid schemes to combat the new scenarios developed as a resul...
Impact of COVID-19 Pandemic on British Foundries
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BACKGROUND The typical findings of COVID-19 pneumonia include multilobar ground-glass opacities and consolidation areas observed predominantly in the basal and peripheral parts of both lungs in computed tomography. OBJECTIVE The current study aimed to show the correlation of indeterminate lesions of COVID-19 pneumonia ...
Correlation of Indeterminate Lesiıons of Covid-19 Pneumonia Detected on Computed Tomography with RT-PCR Results.
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Abstract During the first few months of the COVID-19 pandemic, Canadian nursing homes implemented strict no-visitor policies to reduce the risk of introducing COVID-19 in these settings. There are now growing concerns that the risks associated with restricted access to family caregivers and visitors have started to out...
Finding the Right Balance: An Evidence-Informed Guidance Document to Support the Re-Opening of Canadian Nursing Homes to Family Caregivers and Visitors during the COVID-19 Pandemic
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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) surface spike glycoprotein - a major antibody target - is critical for virus entry via engagement of human angiotensin-converting enzyme 2 (ACE2) receptor. Despite successes with existing vaccines and therapies that primarily target the receptor binding domai...
Adaptation-proof SARS-CoV-2 vaccine design
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BACKGROUND: With a heightened increase in concern for an influenza pandemic we sought to better understand the 1918 Influenza pandemic, the most devastating epidemic of the previous century. METHODOLOGY/PRINCIPAL FINDINGS: We use data from several communities in Maryland, USA as well as two ships that experienced well-...
Transmissibility of the Influenza Virus in the 1918 Pandemic
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BACKGROUND/PURPOSE: In Japan, medical and dental care is provided by the universal health insurance system. The Ministry of Health, Labour, and Welfare (MHLW) in Japan sets the rules for health care services provided by health insurance. The MHLW issued a notice in 2020 permitting telemedicine and dental telemedicine f...
Effect of COVID-19 on dental telemedicine in Japan
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A nurse-midwife describes her experience being ill with COVID-19.
My Coronavirus Experience
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Machine Learning is a seeing gradual acceptance in every other field and hence healthcare is not an exception. Machine Learning in healthcare is useful for various works like suggesting judgments, presenting timely risk scores and specific resource allocation. Thus Machine Learning has become an important factor during...
Icu Admission Prediction Using Machine Learning for Covid-19 Patients
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During COVID-19 pandemic, a wide variety of stroke typologies have been described in patients affected by SARS-CoV-2. Investigating the case reports of acute stroke in COVID-19 patients, published since the beginning of the pandemic, we tried to trace the pathogenic mechanisms of stroke during SARS-CoV-2 infection. We ...
COVID-19 and stroke: from the cases to the causes.
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There is currently no proven effective therapy for COVID-19 Without wishing to be exhaustive, the drugs most studied in this regard are presented below Each of the listed therapeutic options is considered experimental at this stage However, given the severe public health implications of the epidemic and the potentially...
[Pharmacotherapeutic options for SARS-CoV-2 infection / COVID-19]
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BACKGROUND: In this study, the ability of antimicrobial photodynamic therapy (aPDT) as a treatment approach and adjuvant therapy using curcumin-poly (lactic-co-glycolic acid) nanoparticles (Cur@PLGA-NPs) to inactivate Coronavirus disease 2019 (COVID-19) in plasma was investigated. Furthermore, to verify whether the qua...
Robust antimicrobial photodynamic therapy with curcumin-poly (lactic-co-glycolic acid) nanoparticles against COVID-19: A preliminary in vitro study in Vero cell line as a model
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BACKGROUND: Limited evidence is available on the health effects of particulate matter (PM including PM2.5 with an aerodynamic diameter ≤ 2.5 µm; PM10, ≤ 10 µm; PM2.5-10, 2.5-10 µm) during the pandemic of COVID-19 in Italy. The aims of the study were to examine the associations between all-cause mortality an...
Vulnerability and Burden of All-Cause Mortality Associated with Particulate Air Pollution during COVID-19 Pandemic: A Nationwide Observed Study in Italy
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COVID-19 brought out the critical issues of public health messages and the relationship between health literacy, health promotion, and public health. The aim is to analyse these concepts to provide a framework in which mutual influences are ontologically analysed; more specifically this article will explore whether hea...
The paradox of the link between health literacy and health promotion: the case of COVID-19
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Case Presentation: A 74-year-old female nursing home patient with a history of ischemic stroke, hypertension, and obesity presented with fever, dyspnea, and hypoxemia to the emergency department. A chest radiograph demonstrated diffuse bilateral infiltrates and a rapid COVID-19 PCR was positive. She was emergently intu...
Right heart thrombus with high-risk pulmonary embolism in COVID-19 pneumonia, a pocus diagnosis
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This study was conducted to clarify the potential mechanisms of Troxerutin neuroprotection against Lipopolysaccharide (LPS) induced oxidative stress and neuroinflammation through targeting the SIRT1/SIRT3 signaling pathway. To establish a model, a single dose of LPS (500μg/kg body weight) was injected to male Wistar ra...
Troxerutin exerts neuroprotection against lipopolysaccharide (LPS) induced oxidative stress and neuroinflammation through targeting SIRT1/SIRT3 signaling pathway.
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A financial crisis creates substantial wealth losses. How these losses are allocated determines the magnitude of the crisis and the path to recovery. We study how institutions and technological factors that shape default and debt restructuring decisions affect the amplification of aggregate shocks. For sufficiently lar...
Resolution of financial crises
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Latin America has suffered disproportionately during the COVID-19 pandemic. The human impact has been chaotically and catastrophically evident across the three countries we examine here: Colombia, Chile, and México. Those nations were already creaking under the effect of generations of neoliberal ideology: their intell...
Citizenship and neoliberalism: pandemic horror in Latin America: Journal of Media & Cultural Studies
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Objective: This study examined the relationship between worry about COVID-19 infection in general, in the workplace and while commuting to work and psychological distress in the midst of a rapid outbreak of COVID-19 in Japan. Methods: This cross-sectional, internet monitor study was conducted on December 22-26, 2020. S...
Worries about COVID-19 infection and psychological distress at work and while commuting
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During the life cycle of the transmissible gastroenteritis coronavirus (TGEV), two types of virus-related particles are detected in infected swine testis cells: large annular viruses and small dense viruses. We have studied the relationships between these two types of particles. Immunoelectron microscopy showed that th...
Structural maturation of the transmissible gastroenteritis coronavirus.
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SARS-CoV2-induced direct cytopathic effects against type II pneumocytes are suspected to play a role in mediating and perpetuating lung damage. The aim of this study was to evaluate serum KL-6 behavior in COVID-19 patients to investigate its potential role in predicting clinical course. Sixty patients (median age IQR, ...
Serial KL-6 measurements in COVID-19 patients
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Introduction: We aim to estimate the impact of COVID-19 in Immokalee, FL and assess community experiences with workplace conditions, access to testing, sources of information, and contact tracing to inform and strengthen local public health sector efforts in reaching and providing high-quality care to the community. Me...
COVID-19 Pandemic Response in a Migrant Farmworker Community: Excess Mortality, Testing Access and Contact Tracing in Immokalee, Florida
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Coronavirus disease 2019 (COVID-19) has gained prominence as a global pandemic. Studies have suggested that systemic alterations persist in a considerable proportion of COVID-19 patients after hospital discharge. We used proteomic and metabolomic approaches to analyze plasma samples obtained from 30 healthy subjects an...
Plasma proteomic and metabolomic characterization of COVID-19 survivors 6 months after discharge
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The epidemic outbreak of severe acute respiratory syndrome (SARS) in 2003 was caused by a novel coronavirus (CoV), designated SARS-CoV. The RNA genome of SARS-CoV is complexed by the nucleocapsid protein (N) to form a helical nucleocapsid. Besides this primary function, N seems to be involved in apoptotic scenarios. We...
Cell Type-Specific Cleavage of Nucleocapsid Protein by Effector Caspases during SARS Coronavirus Infection
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Viral RNAs can perturb the miRNA regulatory network, competing with host RNAs as part of their infective process. An in silico competing endogenous RNA (ceRNA) analysis has been carried on SARS-CoV-2. The results suggest that, in humans, the decrease of microRNA activity caused by viral RNAs can lead to a perturbation ...
ceRNA analysis of SARS-CoV-2
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BACKGROUND Cuffed tracheal tubes have recently been recommended for selective endobronchial intubation to establish single-lung ventilation even in smaller children. This implies that, compared to uncuffed tracheal tubes, the cuffed tracheal tubes selected will be smaller and therefore have a shorter length. We hypothe...
Simulated dimensional compatibility of uncuffed and cuffed tracheal tubes for selective endobronchial intubation in children.
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COVID-19 has caused an unprecedented amount of mental and economic turmoil with ever increasing fatality and no vaccination in sight Here, feedback control theory based regulation of daily tests and quarantine is proposed to guarantee prescribed degree of exponential decay in number of infections A dynamic model of COV...
Stabilizing COVID-19 Infections in US by Feedback Control based Test and Quarantine
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The pandemic caused by SARS-CoV-2 has caused widespread infection and significant mortality across the globe Combined virology perspective of SARS-CoV-2 with a deep-rooted understanding of pathophysiological and immunological processes underlying the clinical manifestations of COVID-19 is of prime importance The charac...
Murine-β-coronavirus-induced neuropathogenesis sheds light on CNS pathobiology of SARS-CoV2
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COVID-19 caused large-scale, long-lasting lockdowns in many parts of the world, which resulted in many people in need for financial or other aids. Governments, charities, and communities rushed to provide help. To complement these efforts and to provide direct assistance to individuals who may not get sufficient and/or...
A Privacy-Preserving and Overhead-Free Protocol for Direct Donations to People Impacted by COVID-19 Lockdowns
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BACKGROUND: Psychosis, even in its early stages, is associated with significant disability, causing it to be ranked ahead of paraplegia and blindness in those aged 18–35 in terms of years lived with disability. Current pharmacological and psychological interventions intervention have focused primarily on the reduction ...
Cognitive Remediation and Social Recovery in Early Psychosis (CReSt-R): protocol for a pilot randomised controlled study
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Value-of-information analysis (VOI) is a decision-theoretic approach that is used to inform reimbursement decisions, optimise trial design and set research priorities. The application of VOI analysis for informing policy decisions in practice has been limited due, in part, to the perceived complexity associated with th...
A Review of Web-Based Tools for Value-of-Information Analysis.
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Humankind is facing its worst pandemic of the twenty-first century, due to infection of a novel coronavirus named as SARS-CoV2, started from Wuhan in China. Till now, 15 million people are infected, causing more than 600,000 deaths. The disease, commonly known as, COVID-19, was initially thought to be associated with A...
"Silent Hypoxemia" Leads to Vicious Cycle of Infection, Coagulopathy and Cytokine Storm in COVID-19: Can Prophylactic Oxygen Therapy Prevent It?
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Using a new survey conducted with Chinese households on the effects of the COVID-19 pandemic by the Survey and Research Center for China Household Finance, this study provides descriptive evidence on the impact of COVID-19 on household-owned businesses We use ordinary least squares and ordered probit regression methods...
Household-owned Businesses’ Vulnerability to the COVID-19 Pandemic
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BACKGROUND AND AIM: Hemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory syndrome that is induced by hyper-activated macrophages, cytotoxic T cells, and reduced natural killer cell activity. A 46-year-old gentleman presented to us with complaints of intermittent fever for the past 2 weeks associated w...
Inactivated COVID-19 vaccine triggering hemophagocytic lymphohistiocytosis in an immunocompetent adult - A case report
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Covid-19 continues to teach the global community important lessons about preparedness for research and effective action to respond to emerging health threats. We share the COVID-19 experiences of a pre-existing cross-site ethics network-the Global Health Bioethics Network-which brings together researchers and practitio...
A network of empirical ethics teams embedded in research programmes across multiple sites: opportunities and challenges in contributing to COVID-19 research and responses (preprint)/ en
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In the absence of any proper clinical solution, human civilization is only left with sophisticated intervention measures to contain the spread of COVID-19. However, the existing models to estimate the intervention does not take into account the realistic connectivity of the epicentres of the pandemic. We generalise our...
Dynamics of Interacting Hotspots - II
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The COVID-19 pandemic brought into stark relief the intimate nexus between health and housing. This extraordinary infectious disease outbreak combined with the astounding lack of a clear, coordinated, prompt, and effective public health response in the U.S. created conditions and introduced practical challenges that le...
Health, housing, and ‘direct threats’ during a pandemic
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PURPOSE: This study examined the impact of the COVID-19 pandemic on emergency department CT use for acute nontraumatic abdominal pain, to better understand why imaging volume so drastically decreased during the COVID-19 pandemic. METHODS: This was a retrospective review of emergency imaging volumes from January 5 to Ma...
Impact of the COVID-19 pandemic on emergency department CT for suspected diverticulitis
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AIM This study aimed to clarify the construct validity of the Questionnaire for medical checkup of old-old (QMCOO). METHODS In this cross-sectional study, questionnaires including the QMCOO were distributed to 1,953 older adults, and responses were returned by mail. We conducted an exploratory factor analysis (EFA) for...
[Construct validity in structural perspectives of the Questionnaire for medical checkup of old-old among community-dwelling older adults: A pilot study of a countermeasure against COVID-19].
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Transcriptionally active chromatin is marked by tri-methylation of histone H3 at lysine 4 (H3K4me3) located after first exons and around transcription start sites. This epigenetic mark is typically restricted to narrow regions at the 5`end of the gene body, though a small subset of genes have a broad H3K4me3 domain whi...
The dynamic broad epigenetic (H3K4me3, H3K27ac) domain as a mark of essential genes
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INTRODUCTION: With the accelerating pace of ageing, healthy ageing has become a major challenge for all societies worldwide. Based on that Healthy Ageing concept proposed by the WHO, the SoBeezy intervention has been designed through an older person-centred and integrated approach. The programme creates the environment...
Prospective pragmatic quasi-experimental study to assess the impact and effectiveness of an innovative large-scale public health intervention to foster healthy ageing in place: the SoBeezy program protocol
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OBJECTIVES: UK National Health Service/Health and Social Care (NHS/HSC) data are variably shared between healthcare organisations for direct care, and increasingly de-identified for research. Few large-scale studies have examined public opinion on sharing, including of mental health (MH) versus physical health (PH) dat...
Public opinion on sharing data from health services for clinical and research purposes without explicit consent: an anonymous online survey in the UK
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This book offers educators, counselors and parents of 3-16-year old gifted, talented, curious, and creative children and youths a new, original tool of assessing their interests and abilities. As this book has been published during the second wave of the COVID-19 pandemic, it concentrates on ways of assessment that can...
Dynamic on-line assessment of gifted children
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OBJECTIVES We present a case of transumbilical laparoendoscopic single-site surgery (LESS) for partial nephrectomy in a child. METHODS On May 22, 2009, we performed LESS partial nephrectomy on a 7-year-old girl with a 3.5-cm renal mass. The surgery was performed using a homemade single-port device inserted through a si...
Pediatric laparoendoscopic single-site partial nephrectomy: initial report.
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By 2030, more than 80% of Europe’s population will live in an urban environment. The urban exposome, consisting of factors such as where we live and work, where and what we eat, our social network, and what chemical and physical hazards we are exposed to, provides important targets to improve population health. The EXP...
Developing the building blocks to elucidate the impact of the urban exposome on cardiometabolic-pulmonary disease: The EU EXPANSE project
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OBJECTIVE: Involvement in the tracheostomy procedure for COVID-19 patients can lead to a feeling of fear in medical staff. To address concerns over infection, we gathered and analyzed experiences with tracheostomy in the COVID-19 patient population from all over Japan. METHODS: The data for health-care workers involved...
Management of tracheostomy in COVID-19 patients: The Japanese experience
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Hspb8 is a member of the small heat shock protein (sHSP) family. Its expression is known to be upregulated under heat shock. This protein interacts with different partners and can, therefore, be involved in various processes relevant to tissue integrity and functioning. In humans, mutations in the gene encoding Hspb8 c...
Characterization of Hspb8 in Zebrafish
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The causative agent of the COVID-19 pandemic, SARS-CoV-2, is steadily mutating during continuous transmission among humans. Such mutations can occur in the spike (S) protein that binds to the ACE2 receptor and is cleaved by TMPRSS2. However, whether S mutations affect SARS-CoV-2 cell entry remains unknown. Here, we sho...
SARS-CoV-2 D614G spike mutation increases entry efficiency with enhanced ACE2-binding affinity
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Home care for elderly people is an important part of the social welfare system. The sector employs many people, especially women, and work environment issues are common. This review explores the scientific literature on organizational interventions that target the home care work environment. Altogether, 16 studies of v...
Picking low hanging fruit - A scoping review of work environment related interventions in the home care sector.
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新冠肺炎疫情期间,如何在远程模式下完成并达到教学目标是课程学习的关键 我们设计了局部解剖学远程教学模式,并依据远程教学的特点,从课程准备到整体框架,从如何实施到注意的问题,进行了全面分析和总结
Design and practice of regional anatomy using online teaching during COVID-19 pandemic
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ABSTRACT Objectives To evaluate the potential impact of the COVID-19 pandemic on out-of-hospital cardiac arrest (OHCA) response and outcomes in two US communities with relatively low infection rates Background Studies in areas with high COVID-19 infection rates indicate that the pandemic has had direct and indirect eff...
Out-of-Hospital Cardiac Arrest Response and Outcomes During the COVID-19 Pandemic
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Wildfires produce smoke that can carry organic compounds to a vineyard, which are then absorbed by the grape berry and result in wines with elevated levels of smoke-related phenols. These phenols have been found to have a large impact on the flavor of wines, being the cause of a smokey flavor with a lasting ashy aftert...
Evaluation of Different Interstimulus Rinse Protocols on Smoke Attribute Perception in Wildfire-Affected Wines.
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The post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection-also referred to as Long COVID-have been described, but whether breakthrough SARS-CoV-2 infection (BTI) in vaccinated people results in post-acute sequelae is not clear. In this study, we used the US Department of Veterans...
Long COVID after breakthrough SARS-CoV-2 infection.
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INTRODUCTION: During an epidemic, screening processes can play a crucial role in limiting the spread of the infection. The aim of this study was to describe the epidemiological profile of COVID-19 suspected cases and to evaluate the performance of the triage process in predicting COVID-19 in Southern Tunisia. METHODS: ...
Epidemiological profile and performance of triage decision-making process of COVID-19 suspected cases in southern Tunisia
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CORD 19

Dataset Summary

In response to the COVID-19 pandemic, the White House and a coalition of leading research groups have prepared the COVID-19 Open Research Dataset (CORD-19). CORD-19 is a resource of over 1,000,000 scholarly articles, including over 400,000 with full text, about COVID-19, SARS-CoV-2, and related coronaviruses. This freely available dataset is provided to the global research community to apply recent advances in natural language processing and other AI techniques to generate new insights in support of the ongoing fight against this infectious disease. This is a processed version of the dataset, where we removed some empty entries and formated it to be compatible with the alpaca training. For more details on the data, please refer to the original publicatio.

Citation Information

@inproceedings{wang-etal-2020-cord,
    title = "{CORD-19}: The {COVID-19} Open Research Dataset",
    author = "Wang, Lucy Lu  and Lo, Kyle  and Chandrasekhar, Yoganand  and Reas, Russell  and Yang, Jiangjiang  and Burdick, Doug  and Eide, Darrin  and Funk, Kathryn  and Katsis, Yannis  and Kinney, Rodney Michael  and Li, Yunyao  and Liu, Ziyang  and Merrill, William  and Mooney, Paul  and Murdick, Dewey A.  and Rishi, Devvret  and Sheehan, Jerry  and Shen, Zhihong  and Stilson, Brandon  and Wade, Alex D.  and Wang, Kuansan  and Wang, Nancy Xin Ru  and Wilhelm, Christopher  and Xie, Boya  and Raymond, Douglas M.  and Weld, Daniel S.  and Etzioni, Oren  and Kohlmeier, Sebastian",
    booktitle = "Proceedings of the 1st Workshop on {NLP} for {COVID-19} at {ACL} 2020",
    month = jul,
    year = "2020",
    address = "Online",
    publisher = "Association for Computational Linguistics",
    url = "https://www.aclweb.org/anthology/2020.nlpcovid19-acl.1"
}
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